LOCUS       gnlProkkaPJDNGGHJ_10   13214 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PJDNGGHJ_10.
ACCESSION   gnlProkkaPJDNGGHJ_10
VERSION     gnlProkkaPJDNGGHJ_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:10:23
            Original ID  :: gnl|Prokka|PJDNGGHJ_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13214
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13214
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[616:3214]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      617..3214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..13214
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13214
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(80..211)
                     /gene="allorf_000080_000211"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_000080_000211"
                     /protein_id="allorf_000080_000211"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDEQMNEVLELQQLSKGSEVETAGWTLLTTLIGTSTISNSCNK"
     CDS_motif       complement(149..211)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MDEQMNEVLELQQLSKGSEVE"
                     /locus_tag="allorf_000080_000211_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(80..148)
                     /prepeptide="core"
                     /locus_tag="allorf_000080_000211_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.30"
                     /molecular_weight="2120.4"
                     /monoisotopic_mass="2119.2"
                     /core_sequence="TAGWTLLTTLIGTSTISNSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDEQMNEVLELQQLSKGSEVE"
                     /leader_location="[148:211](-)"
                     /alternative_weights="2138.4"
                     /alternative_weights="2156.4"
                     /alternative_weights="2174.4"
                     /alternative_weights="2192.5"
                     /alternative_weights="2210.5"
                     /alternative_weights="2228.5"
                     /alternative_weights="2246.5"
                     /alternative_weights="2264.5"
     CDS             complement(226..354)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGTEVEASKGKGGLLTLITTIVGSSTISNNC"
     CDS_motif       complement(283..354)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="ctg10_1_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(226..282)
                     /prepeptide="core"
                     /locus_tag="ctg10_1_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1724.0"
                     /monoisotopic_mass="1723.0"
                     /core_sequence="LLTLITTIVGSSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[282:354](-)"
                     /alternative_weights="1742.0"
                     /alternative_weights="1760.0"
                     /alternative_weights="1778.1"
                     /alternative_weights="1796.1"
                     /alternative_weights="1814.1"
                     /alternative_weights="1832.1"
     CDS             complement(406..525)
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MKEVLVLQQFDEKSEVEPTAWTVTLTTISVTLSTLSNHC"
     CDS             complement(617..3214)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 73.3;
                     E-value: 3.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_3"
                     /sec_met_domain="micKC (E-value: 9.8e-144, bitscore: 473.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.4e-17, bitscore: 57.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.2e-09, bitscore:
                     29.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLVYFQHMSEDSKYYIEKSPNAETDPYEVHNIPNYYTVSTEY
                     KSPWKFYNNPNHTLKEQGWKIHVSATMNNAQDILEVVSQIIFKHQIPFKHIKDKQSLFN
                     MNSKHGNRTSSGKFIAIYPSSNNMFFRLLNELYEELKHYENGPYILNDKSWKDSNIYYR
                     YGAFKNIYNERGELCIKDENGNLIPDNRQPYYKIPEFVSDFDQYLDSKNNLLDTQDVSN
                     FNDYEFQGVLRFNNGGGIYTGIRKLDGKKVVIKEGRPKVGLDGQFNDAIDRLNIEYEAL
                     NKLTDVEGVVNVLDYFKAWKHVFLVEEFVEGVTLQTWCAINYPFNVENDKNEYISKVKK
                     IINSLVKTIKLVHSKDVGMGDLQPQNIMITPESNVKIIDFEAASALSEENGALQTIGYT
                     NKKNKNHKERDWYALKKVLRFCILPIGPVADIEETIKKKHDMWIEDEFGKDVYQYVVNT
                     ENLCDKYLSDTKEKIFKNSYDSKIQKEMDMSKVIKGLRNSIESNILPNSSLIHGDVRQF
                     VMPSGKLNVLTGGTGAALALYRSGNVSKEVWDWIENVLLEKLNVLNDDVGLFTGRAGIA
                     ATLYELGYIEQAMDLFNNLSYEDMKDISLRSGLSGIGLSLISLYMEENNNDFLVTSEKI
                     ADQIEKRIIEDDKLSVTDFAAVPIGLIDGWSGISLFYAALYSVTKNEKYYLKSKEYIER
                     DLKHCKVDEETNTLQTYDDQNPRLLPYLSGGSIGIGIAIWYLNYVKNNNLFREELEQII
                     NLNKVRIAYSGGLFDGIGSFLLIPPMTKEKNEISQHIELALRKLELFLIRKDDQVLFPG
                     NFSFRLADDYYSGSAGIILGINSIQFSNPLYWLPIIKIDSFLRKTKKELLLNN"
     CDS             complement(3242..5014)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     266.6; E-value: 2.8e-81)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 342.3; E-value:
                     9.1e-104)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MMTNPNFKSKEFFFLLSKTRPNIRLFILAIFLSGLSAIASTLVPH
                     YLKSLIDYYNIHEKINLWDLLGLLGIFLSSGVIGAVGSYMLSVVGYNVVANLRNLLWEK
                     IVILPVEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQ
                     LTLVIVVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISAIRLVKSSTAEKL
                     QVEKGKEDVEALRSIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTF
                     IAFLTLMFYIMGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELAETNKDLV
                     IENLSFCYSNEDKAFSLKNINLIIKRGSVNALVGPSGSGKTTIISILERYYKPNSGNIY
                     FGDENIELFSLNSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPNEKRIVEACKKAYAW
                     QFISELPNSLETNIGEKGLNLSGGQRQRIAIARMFLKNPNIIFLDEATASLDSHSERIV
                     NEAMKKLMKDRTAIIIAHRLSTIINADNIIFMENGEITGQGNHWELKNSHKLYHQFCEQ
                     QFKEDSTDPLVLTN"
     CDS             5466..6848
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 235.6; E-value: 2.1e-71)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_5"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.5e-43, bitscore:
                     142.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRRISIVFIFVIVSSLQPVSSRAEESNHDESIIINLDSKISE
                     STINKVQEKYSNIETNYIKELDLLVINNIKPSQFSAIKDIAKEKLDANEIIEDKEISLP
                     EKSKQIPAKVASSSQFTEDNDTLYDSWLWNIKQVTNDYRSYQINKGSHNTKVGIIDSGI
                     DFNHPDLKKNIVDTGESFVPVEDNTQDFYGHGTSVAGIIAANGDVKGVGPNLGLVPYKV
                     FDKDGKSKRSWVISAIVKATEDDMDVINLSLSTFLSKKDKDDRETIKLFEKAFKFARKH
                     NTLIVAAAGNHGYDISNSKKLAQQLGKPKDNILHLPGGDNDVITVSATTAQNTKASYSN
                     YGKNISIAAPGGDLDTNKIDLYSLVWTTSPVNIPQTPLSKSLGFQKGYEPTLGTSVAAP
                     IVTATAALLKTEYYEKYGEEMPNRKVEENLYQNTDHVENLDKNEVGSGIVNAYESLLNI
                     ER"
     CDS             complement(8277..9677)
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MNQHQKKAPAELKIGQTFPLTIKRLGINGEGVGYFKKKVVFVPGA
                     LPGEEVVAEATNVQPKFSEARVKKIRKPSEHRVTPPCPVYDQCGGCQLQHLAYSQQLRE
                     KRDIVIQSLERHTRFNVEEMNIKETIGMDNPWNYRNKSQFQVGRSQSGSIIAGLYGLDS
                     HKIVPIKECIVQHPATNKTTGIVRRILEKHNVSVYNERTKKGDVRTIVTRVGFETGEVQ
                     VVLVTAKETLPNKDEIVKAIQNRLPEVKSIIQNINGARTSVIFGDKTKALAGSHAIQEV
                     LGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMWVSSGAK
                     EIRGMDVIKESIDDAKKNAKKHGIKNAAYVTGTAEHWLPKWTKEGFRPDVVIVDPPRTG
                     CDGTFLDTIKKVKPKRFVYVSCNPSTLAKDLQALSKDYRVEYIQPVDMFPQTAHVEAVA
                     KLVLKSSN"
     CDS             complement(9850..10713)
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MWEETVSVTPPYHFDKVLERLSLDPLNAVDLTARSIKVPLRTRDG
                     KLSVITVQAKGTAIDPVFLVSGETDREEMIERIKHIFQWEQPLQPVLDHFSKTNLSALF
                     EEHAGTPLVLEYDVYNCLMKCIIHQQLNLSFAFTLTERFVHAFGEQKDGVWCYPEPKTI
                     AALEYQDLRELQFSMRKAEYAIDLSRMIADGALNLAELPQLSDEDIMKKLITIRGIGPW
                     TVQNVLMFGLGRPNLFPLADIGLQNAVKRRFALEDKPSKDLMLQVSREWAPYLSYASLY
                     LWRSIE"
     CDS             10820..11779
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MIHITAITTHNEILDNIPLSRTEQPDIAWYWIDFFGAEMHETELL
                     RDYFHFHPLAIEDCFQHMQRPKIDHYDGYRFYVLHALNPDTLEMEEVDIFQSDRFIVSF
                     HLHESPGISRVRERFFASPGLAKKGPGHITYMIMDQLVDEYFPVLYKIEDRLNEIEDSR
                     THKSYGTLMNEVFELRTDLLNLRRTIIPMRDLMYRILSLDHVKESRETKAYFSDIYDHL
                     LKLAELIESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYGMNFDN
                     MPELHWKYGYFIVLGVMAALVAAMLFWFARKGWFNIFK"
     CDS             11843..12490
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MCAVTILSHKTISSALLLLSVMSIAPLYNGCTMSDYIFEWLGFSS
                     WSEDGAHISVIPGVVLYFAALIWCAASFRRTLPAVGLFLIFLSMGVSSSISPVTEYAAF
                     SLKQFAPERKAVEYLKHRSECSHLIERKKARMSCTIYINYYGKGEQTISITPDLSENVK
                     GVTFKSKTFTVKPRSKTIIKAQFTGFYKGKAASDSGWSSEPDLKVASLHTAE"
ORIGIN
        1 tttgaagctt ctacttcagt tccttcactc agttgttgaa gttccaatac atctctcatt
       61 caatttcacc tcctttttat tatttattac agctattgct aatagtagat gtaccgatga
      121 gtgttgttag aagtgtccac ccagctgttt ctacttctga acctttactc aattgttgca
      181 actctagtac ttcattcatt tgttcatcca ctcctcttaa atatcttaac agttgttgct
      241 aatagtagat gagccaacta tcgttgtgat tagtgtaagt aagccacctt tgccttttga
      301 agcttctact tcagttcctt cattcagttg ttgaagttcc aatacatctt tcatttagtt
      361 tcacctcctt tcaagtactc tttcttagat tatccttctc tctcattagc aatgattact
      421 aagggtagat aatgtaactg aaatagttgt tagagtaaca gtccatgccg taggctccac
      481 ttcagatttt tcatcaaatt gttgaagtac cagcacctct ttcattttct tttctcacct
      541 cccttcataa gttctgtata ttaactgctt taattctaat cttcaatgat tatcatcgaa
      601 tataagtgtt agagttttaa ttgtttaata acaattcttt ttttgtcttt cttaagaaac
      661 tatcaatttt tattattggc aaccaatata acggatttga aaactggata gagtttatgc
      721 ccaatattat gccagcactt ccggagtagt aatcatctgc taaacgaaag ctgaagtttc
      781 cagggaataa tacttgatca tctttgcgga taagaaacaa ttctagtttt ctcaatgcca
      841 gctcaatatg ctgactgatt tcattttttt ccttagtcat tggcgggatt aacaagaaac
      901 taccgatccc atcaaacaat ccaccgctat atgcgatcct tactttattt aaattgatta
      961 tttgctctaa ttcttctcta aataaattat tattttttac ataatttaaa taccaaatag
     1021 caattcctat tccgattgat cccccagata aatagggtaa taatcgaggg ttttgatcat
     1081 catatgtttg caaagtattc gtctcttcat ctaccttaca atgttttaaa tctcgctcaa
     1141 tatattcttt tgattttaaa taatattttt cattcttagt aactgaatat aatgccgcat
     1201 agaataaaga tattcctgac caaccatcaa tcaaacctat aggtactgct gcaaaatcag
     1261 tcactgataa tttatcatct tcaataatcc ttttttctat ctgatcagca attttttcag
     1321 aagtaaccaa aaaatcatta ttattttctt ccatgtataa gctaattaat gaaagaccta
     1381 ttcccgacaa tcctgacctt aatgaaatat ctttcatatc ttcatatgac agattattga
     1441 ataagtccat agcttgctct atgtatccca attcatacaa tgttgctgcg ataccagctc
     1501 gtcctgtaaa taacccaaca tcatcattaa gaacattcaa tttttcaagt aaaacatttt
     1561 caatccaatc ccaaacttcc ttgctgacgt ttccagatct gtacaatgcc aatgcagctc
     1621 cagttccccc agttagtaca tttaactttc cagatggcat tacaaattgc cgtacatcgc
     1681 catgaattag cgagctgttg ggcaaaatat tactctctat actgtttctc aatcctttta
     1741 ttacttttga catgtccatt tctttttgta ttttactgtc ataactattc ttgaatatct
     1801 tttctttggt gtcagataag tatttgtcac atagattttc tgtatttaca acatattgat
     1861 agacatcttt gccaaactcg tcctctatcc acatatcatg tttcttttta atggtttctt
     1921 ctatatcagc aaccggacct attggcagaa tacaaaatct taaaactttc tttagtgcat
     1981 accaatcacg ctctttatga ttcttatttt tcttatttgt gtagccaatt gtttgcaacg
     2041 ctccgttttc ttcagagaga gcactagcag cctcaaaatc aataatctta acatttgatt
     2101 cgggggttat cattatattt tggggttgta aatctcccat accaacatct ttactatgca
     2161 ctagtttaat tgttttgacc aagctattaa ttattttttt caccttacta atgtattcat
     2221 ttttatcatt ttcaacgttg aacggataat tgattgcaca ccaggtttga agagttacac
     2281 cttctacaaa ctcttcaact aaaaatacat gtttccaagc tttaaagtaa tcaagtacat
     2341 taacaacacc ttcaacatct gtaagtttat ttaatgcttc gtattctata ttcaatctat
     2401 caatcgcatc attaaattga ccatctaacc ctactttagg tcttccttct ttgattacta
     2461 cttttttccc atccaatttc cttattccag tatatatacc gccaccatta ttaaacctaa
     2521 ggactccttg gaactcataa tcattaaaat tacttacatc ttgagtatct aataagttat
     2581 tcttggaatc taaatactga tcaaaatcac ttacgaattc aggtatttta taatacggct
     2641 gtctattatc cggaattagg tttccatttt cgtctttaat acaaagttct cctctttcat
     2701 tgtaaatatt cttaaacgca ccatatcggt aatatatatt gctgtccttc cacgatttat
     2761 catttagtat gtatggtcca ttctcataat gttttaattc ttcataaagt tcattcaata
     2821 acctgaagaa catgttatta gaggaaggat agatagcgat aaattttcca gatgaagttc
     2881 gattaccatg cttcgaattc atattaaata gagattgttt atctttaata tgtttaaatg
     2941 gtatctgatg tttaaatata atttgactca caacttctaa tatatcctga gcattattca
     3001 ttgttgcact tacgtgtatt ttccagcctt gttctttgag ggtatgattt ggattattat
     3061 aaaacttcca tggtgatttg tattctgtac taacagtata gtaatttggt atattatgta
     3121 cttcatatgg atcagtctct gcatttgggc ttttctctat atagtatttt gaatcttcac
     3181 tcatgtgttg gaaataaact aattttttgt ccattttgtt ttcgcctctc ttaagccgct
     3241 cttaattggt taatactaat ggatcggtac tatcttcttt aaactgctgc tcacagaatt
     3301 gatgatacaa tttatgacta ttctttaact cccaatgatt cccttgacct gtgatctcac
     3361 cgttttccat aaaaatgata ttgtcagcat ttataatggt ggataaccta tgtgctatta
     3421 taatagcggt tctatccttc ataagcttct tcattgcttc gttcacaatt cgttcagaat
     3481 gactgtcaag acttgcagtt gcttcatcta aaaagattat atttggattc ttcagaaaca
     3541 ttctcgcaat agcaattctt tgtcgttgtc ctcctgataa gttcagacct ttttctccaa
     3601 tattagtttc taaactgtta ggcaattcac ttataaattg ccatgcatat gccttcttac
     3661 atgcttctac tattcttttt tcatttgggg gattttctaa accaaagatg agattgtctc
     3721 taatagtacc gcttattaaa tcatgattct gtgctacata tcctatttgg ctacgccatg
     3781 aatttaatga aaataactca atattctcgt caccaaaata aatatttccg ctgttgggct
     3841 tgtagtatct ctccagaata gagatgattg tggttttacc actaccacta ggacctacta
     3901 aggcattaac acttcctctt tttattatta aattaatatt tttcaaggaa aatgctttat
     3961 cctcattact gtagcaaaat gataaatttt caatcactaa atctttattg gtttccgcta
     4021 attcttttcc tttatgctga tcttctcctt gctcatatat caattgagaa attctttctg
     4081 ttgcacctat tgtcttttgt atttgagtaa agaatagccc aaagttatta agtggaccca
     4141 tgatatagaa cataagtgtc agaaatgcta taaacgttcc tggcgataaa cttccattgg
     4201 ctaatttaac ccctccgaat ccaattatgc taataatgat aagcatcatc attaaattaa
     4261 tgatagggtt taaaataacc atccattttg tctgctttag gcctatgctt cttaaagctt
     4321 caacatcttc ttttcctttt tctacttgta atttttctgc agttgaagat ttaaccagtc
     4381 ttattgcaga tattgtttca acagctctta catttaattc acctgttaag ctttgcgtca
     4441 ttttagataa tttagataaa attcttccta aaggtataaa aattaataaa taaactggaa
     4501 ttgctacgac aatcactagt gtcaattgcc aatcatagta aaacaaccaa aatccacaaa
     4561 aaagcactat taatatagca ttgataaatt gcgaaaaaga gttacttact aagttgtaaa
     4621 tcaccgtagt atcattaaca aatctacttg ctatatccgc agaacgattc ttatcgtaaa
     4681 attctacagg cagtataact atcttttccc ataataaatt tctgagattt gcgacaacat
     4741 tatatcctac tacacttaac atataactac caactgcccc aattactccg ctgcttaaaa
     4801 atatccctag cagtcctaat aggtcccaca aattgatctt ttcatgaata ttgtaatagt
     4861 ctattagact ttttaaataa tgaggcacta aggtagaagc tattgcgctt aatccactta
     4921 aaaatattgc caatataaat aatcttatat tcggtctggt tttactcagt aagaagaaaa
     4981 actctttcga tttaaaatta gggttggtca tcattttcac ctctttcgtt taattccaat
     5041 gtctcaactt tttatatcga atgactcttg aaatgacata cgccatatct ttcctgattt
     5101 tcctataaac aatatttcac actcaataac tgtaagtcaa tatataattt tacaaattat
     5161 aaaaaaacag gtctttggtt atacattatt ctacttttgt atattacgaa atgtatattc
     5221 actcttaata tttctgccca caaaaccata ggcgtagtat aaaagaataa aaagaaattt
     5281 aaattaatca tactaaaggg acgtttccgg ggataatcac ttctaattag aaaaatatgc
     5341 attgactgat ttacttatat tttataaaat tgaattaaat atacttatat ttcatttttt
     5401 ggaatgggag ggtgaattat atacaatctt ataatgaaat gtataaagag aaaggagtat
     5461 aaaaaatgaa gaatttaaga agaatttcga tagttttcat atttgtaatt gtatctagtt
     5521 tacaacctgt tagctctcgt gctgaagaat caaatcatga tgaatctatc ataattaacc
     5581 tcgactcaaa aattagtgaa tcgacaataa acaaggttca ggaaaagtat tcaaatatag
     5641 aaacaaatta tattaaagaa ctagatttat tggtaataaa taatataaaa ccaagccaat
     5701 tctcagcaat caaagatatt gctaaagaaa aattagacgc aaatgaaatt attgaggata
     5761 aagaaatttc tcttcctgaa aaaagtaaac agattcctgc taaagtggca tcttcatcac
     5821 aattcacgga agataatgac actctttatg acagttggtt atggaatatc aagcaagtta
     5881 caaatgatta tcgaagttat cagataaata aaggatctca taatacaaaa gtagggataa
     5941 tcgattcagg catagatttc aatcatccag acctcaaaaa aaatattgta gatactggag
     6001 agtcttttgt tccagttgaa gataatacac aagactttta tgggcatgga acttctgtgg
     6061 ctggaataat tgctgctaat ggggatgtaa aaggagttgg accaaatctt ggtttagtgc
     6121 cgtataaagt atttgataaa gacggtaaat ctaaaagaag ttgggttata agcgcaattg
     6181 ttaaagctac ggaagatgat atggacgtaa ttaatttaag tttatctact tttttatcaa
     6241 aaaaagataa agatgataga gagactataa aactttttga aaaagctttt aaattcgcta
     6301 gaaaacacaa tactttaatt gttgcagcag ctggaaacca tggatatgat atctcaaatt
     6361 caaaaaaact tgcacaacaa ttaggtaaac caaaggacaa tatcctacat cttcctggtg
     6421 gagataacga tgtaattact gtatctgcca ccacagcgca aaatacaaaa gcttcttact
     6481 caaattatgg aaaaaacatc tcaattgcag ccccaggtgg tgatctggat acaaataaga
     6541 ttgatctata tagcttggta tggactactt cccctgtcaa tatcccgcaa actccgctaa
     6601 gtaagtcact aggctttcaa aagggatatg aacctacttt agggacaagt gtagcagctc
     6661 caatagtaac tgctacagca gccctattaa agacagaata ctacgaaaaa tatggagagg
     6721 aaatgccaaa tcgtaaggtt gaagaaaact tatatcagaa cacagaccac gttgaaaact
     6781 tagataagaa tgaagtaggt agcggtatcg taaatgctta cgaatcattg cttaatattg
     6841 agagataaaa gatattaagc agttctcgaa cttcactaaa aatactttga ttaataaaaa
     6901 aagattacta gacgataatg atgatgaagt agagatgaaa taaattatat ttacgggata
     6961 ttgagaataa ctaaataagt taagttcaca agcaacttaa tattactaag ttgcttgtgt
     7021 catattttat ttcagcctga gtattcaatt ctttagctat tgttgatttc tttatcgcac
     7081 aaaacccagc atgtagcagc accttataaa cagaccaatt ctttcccttg ctttaatcta
     7141 tcttcaatag cccacttacc ttccttaccc taaatccctc tatacgattt tgtgtacgga
     7201 ctaaattttg attacggaac catgaaccga ctcataaagt tctcctaaaa tttaagggct
     7261 cactctagtt ggttttcttt ctgtttgtaa aacaattcat actattatta ctccttcttt
     7321 agcagtccca aacactcttt atctctcttc ccaatcaaca gtgcttttct cttgttattc
     7381 ggctttattc tcggtgttac tttgtaatac cattcccaat catacttaca aaatccacgt
     7441 atgcagccct tttgctgtcc tacccaatcc aacaattgtc tcatcaaaat agggacagcg
     7501 atacttgaag caagtaatgt aaactaaaac aagtcgctcc aataaatcca attatcagac
     7561 ctctttttat attgcttttc attcaaattc acccttaaca aaccatttca taatcatagt
     7621 gaacaattag ctaattaagc aaaatgtaac gatgccaact attattaata catgaaaaaa
     7681 tgcacctgtc ataggacagt tgcaaaggcc ttactagaac tagagcatca gcatgttgtc
     7741 tacgctaagc caaaaagtgg ttattacatt gttgactatt atcaaacccc tagtccaatt
     7801 aaagatcata ttgattttat ctgctgatcc ggataaacgc attgccttat cggcacttta
     7861 acattgtatg aatcaagcga tagatcatta taaggagcaa ttattcacgt atagttagca
     7921 acaggggctt tactctttaa aaaaggagtt tacaaaatat tcacaggagt tacaagtatt
     7981 cacgagactt gaacgagtcg ttattgctct tcatattttg tctgtaatac cgtttccaaa
     8041 cgaaaaaaag aatatgttta tggagcagca tgatagaact ttactgttga atcatgttac
     8101 agctttagga attgatctaa aaaatgaggg tttccgcacg ttttttcagc tcttttcgtc
     8161 agtgaaaata aagttctctg agaaaagaca gtcagggcaa aggctcccta tgaaaaagac
     8221 ccggaaatcg gcaaggttca ttctgccgaa atccagatct gatcaggaat cgttttttaa
     8281 ttagacgatt tcaatacaag cttcgccaca gcttccacat gagccgtctg cggaaacata
     8341 tccacaggct gaatatattc gacgcgatag tccttcgaca gcgcctgcaa gtctttcgcc
     8401 agtgtggaag gattgcagga tacgtagacg aagcgtttcg gttttacttt tttgatggta
     8461 tctaaaaatg ttccgtcgca gcccgttctc ggcgggtcga cgatgaccac gtctgggcgg
     8521 aagccttctt tcgtccattt cgggagccag tgttcagctg ttcctgtgac atatgccgcg
     8581 tttttgatgc cgtgtttttt ggcgttcttc ttcgcatcgt caattgattc tttaatgacg
     8641 tccatgccgc ggatctcttt cgccccgctt gagacccaca tgccgatcgt accgacgccg
     8701 caatatgcgt caacgacttt ttcttttccg gtcagctgcg ccgctttttt cacttcgtca
     8761 tacagcttga ccgtctgctc agggttgagc tggaagaaag cgcgggcgct taattcaaat
     8821 gacacgtcac caagtacctc ttgaatggca tggcttccgg ccagcgcttt tgttttgtcc
     8881 ccgaaaatga cggatgtgcg cgcgccgttg atgttttgaa taatcgattt cacttcgggc
     8941 agacgattct gaatggcttt gacgatctcg tctttattcg gaagtgtctc tttcgccgtg
     9001 acaagcacga cctgcacttc gcctgtttca aaaccgactc tcgtcacgat ggtgcggaca
     9061 tcgccttttt tggtccgttc gttataaaca gatacgttgt gtttttccaa tatgcggcgg
     9121 acaatacccg ttgttttgtt cgtcgccgga tgctggacaa tgcattcctt aatcggaaca
     9181 attttatggg aatcaagtcc gtataagccg gcaatgatgc tgccgctttg cgagcgtccg
     9241 acttgaaact ggcttttgtt ccggtaattc cacgggttgt ccattccgat cgtttcttta
     9301 atgttcattt cttcaacatt gaatctcgta tgacgttcca aagactgaat gacgatatcg
     9361 cgcttttcgc gaagctgctg actgtaggcc agatgctgaa gctggcagcc gccgcattga
     9421 tcgtataccg gacaaggcgg cgtgacgcgg tgttcagacg gcttgcggat ttttttgacg
     9481 cgtgcttctg aaaatttcgg ctgaacgttt gtcgcttcgg caacgacttc ttcgccgggc
     9541 agagcgccgg gaacgaagac aacctttttc ttaaaatagc cgacgccctc tccattaatg
     9601 ccgaggcgtt tgatggtcag cggaaatgtc tgtccgattt tcaattcggc aggcgccttt
     9661 ttttgatgtt gattcacgtt ttattctctc cgtttctata ataaagccat cctcatggga
     9721 aaacggctga tttgaaatat cacatctttt cagtataaca tgcagccggc ggttccttca
     9781 tgtttttcac cggaagtttc caaaaaatac tcggaagcga tcaaatgcca tcggtaagcc
     9841 atcttgtttt tattcaatac ttctccacaa atacaaggac gcgtagctta aatacggcgc
     9901 ccattccctg cttacttgaa gcatcaagtc ttttgacggt ttatcctcaa gggcgaagcg
     9961 gcgtttgacg gcgttttgca ggccgatatc tgccaaagga aacagattcg ggcggccgag
    10021 gccgaacatg aggacgtttt ggacggtcca tggcccgatg cctctgatgg tgatcagctt
    10081 tttcataatg tcttcatccg ataactgggg aagttccgca agattgagcg ctccgtctgc
    10141 aatcatccgt gaaaggtcaa tcgcatattc cgcttttctc atgctgaact gaagctcccg
    10201 caagtcctga tactcaagcg ccgcaatcgt tttcggctcg gggtagcacc agacgccgtc
    10261 tttttgttcg ccgaaggcat ggacgaaccg ttccgttaag gtaaaagcga aggacaggtt
    10321 gagctgctgg tggatgatgc atttcatgag acagttgtac acatcgtatt ccagcacgag
    10381 cggggttccc gcatgctctt caaaaagcgc agacagattt gtttttgaaa aatgatcaag
    10441 cacaggctga agcggctgct cccactgaaa aatgtgtttg atccgttcaa tcatctcctc
    10501 gcggtccgtt tcgccgctga cgaggaaaac cggatctatg gcggtgcctt tcgcttgaac
    10561 cgtgatgacc gacagtttgc cgtcccgtgt tctgagcgga actttaattg accttgctgt
    10621 aagatcgacc gcattcagcg gatcgagtga cagcctttca agcactttat caaaatgata
    10681 cggcggcgtg accgaaaccg tttcctccca catatgctcc accccttttt gtccaagtat
    10741 atcacgaagc gttccgacgg caattcgtat acttttcttc ataacgccgc atgatataat
    10801 ggcaggcgga gggttgttta tgatacatat aaccgcaatc acaacacata atgagatatt
    10861 agataatatc cccctatcac gtacagaaca accggacatc gcatggtact ggattgattt
    10921 tttcggagcc gagatgcatg aaaccgagct gctgcgggat tatttccatt ttcatccgct
    10981 cgcgattgag gattgctttc agcacatgca gcggccgaaa atcgaccatt atgacggcta
    11041 ccgtttttat gtgctccacg ccttgaaccc ggacacactg gaaatggaag aggtggacat
    11101 ttttcagtcc gaccgtttca tcgtcagctt ccatctgcac gaatcgcccg gcatctcgag
    11161 agtaagagaa cggtttttcg cttctccggg gttagccaaa aaagggcccg gacacataac
    11221 gtatatgatt atggatcagc ttgtcgatga atatttccct gtgctgtaca aaattgaaga
    11281 ccggctgaat gaaattgaag acagcagaac acataaatct tacggcactt taatgaatga
    11341 agtgtttgaa ttgcggactg atcttttgaa cctgaggcgg acgatcattc cgatgcgcga
    11401 tttaatgtac cggattttga gtcttgacca tgtaaaagaa agccgtgaaa caaaagcata
    11461 tttcagcgat atttacgacc acctgttaaa actggctgag ctgatcgagt caaaccgtga
    11521 tatgacgtca gatctgcggg acagctatgt aacactgaat tcaaaccgga tgaacgccat
    11581 catgatgacg ttaaccatcg tctcgaccat ttttattccg ctcacgttta tcgcgggagt
    11641 ttacggcatg aatttcgata acatgcctga gcttcattgg aaatacgggt attttatcgt
    11701 tttgggtgta atggccgctc ttgtggccgc catgctgttt tggttcgccc gcaaaggctg
    11761 gtttaatatt ttcaagtaag aacggctgcc ggctgttctt ttttttgtga aaacatgata
    11821 tgttggaaaa aaacgtaaag aggtgtgcgc cgttaccatt ctttctcaca aaaccatttc
    11881 ttccgccctt ctgcttctca gtgtcatgtc cattgccccg ctgtataacg gctgtacgat
    11941 gtctgattac atctttgagt ggctcggctt ttcttcttgg tctgaagatg gagcccatat
    12001 ctccgtcatt cccggggtcg tgctatattt tgcggcgtta atctggtgtg ccgcctcgtt
    12061 cagacggacg cttcccgctg tggggctgtt tctgatcttt ctcagcatgg gggtctcttc
    12121 cagcatcagt cctgtcactg aatatgccgc tttttcctta aaacagttcg cgcctgaaag
    12181 aaaagctgtc gaatatctga agcaccgcag tgaatgcagt catctgattg agcgcaaaaa
    12241 agcgagaatg agctgcacga tttatatcaa ttattatgga aaaggggaac aaaccatatc
    12301 tatcacacct gacctatctg agaacgtaaa gggcgtcaca ttcaaatcaa aaacattcac
    12361 tgtaaagccc cgatcgaaaa caatcatcaa ggcgcagttt accggctttt ataaagggaa
    12421 agccgcatca gacagcggat ggtcttcaga acctgaccta aaagttgcaa gcctgcacac
    12481 agcagaataa acgttttgca tgtataatga tggaaaacat ttcattggag ggactgcaaa
    12541 tgaaaatcgc catcgtcgga ctcggcaata tgggccgccc catcgccgaa aatatcatga
    12601 aagccggata cagtctgact gtctataacc ggacgaaaga aaaagcggct gatctgctgg
    12661 agaaaggggc cgaatatgcc aaaacgcccc gtcaggcagc tgaacatgcg gacattgtgc
    12721 tgtcaatgct gtcagacgat gaagccgtaa caggtgtgac tttcgggcct gacggcatta
    12781 ttgccgggtt atctgaaaaa ggcattcata tttcaatgag caccatcagc acggcgctgt
    12841 cagaacagct ttccgctgcg cattcgagca gaggacagtc ctttattgcc gctcccgtcc
    12901 tcggccgtcc cgatgcggct gagaaggccg agctccgcat catcacagcc ggccctcagg
    12961 aagcgaagaa aaaggccgaa ccgctgttta aaagcctggg tcagcaagta tttgacaccg
    13021 gtgaagagac caaaacagcc aacgcggcca aaatcagcat caatttcttg ctcgtttcta
    13081 tgctggaggc gttatctgaa tcattcttaa tgatggagaa gtacggcttg ggccaaaaac
    13141 aatttttaga aatcgccaac gcgctctttg gctctcccgt ctatcaaaat tacggaacca
    13201 tcatgtccga gcag
//
