LOCUS       gnlProkkaNNAPIBNL_2    12869 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NNAPIBNL_2.
ACCESSION   gnlProkkaNNAPIBNL_2
VERSION     gnlProkkaNNAPIBNL_2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:22:10
            Original ID  :: gnl|Prokka|NNAPIBNL_2
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12869
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12869
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[514:2869]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      515..2869
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..12869
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12869
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(124..252)
                     /gene="allorf_00124_00252"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_00124_00252"
                     /protein_id="allorf_00124_00252"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKDVLELQQLNEGTEVEASKGKGGLLTLITTIVGSSTISNNC"
     CDS_motif       complement(181..252)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="allorf_00124_00252_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(124..180)
                     /prepeptide="core"
                     /locus_tag="allorf_00124_00252_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1724.0"
                     /monoisotopic_mass="1723.0"
                     /core_sequence="LLTLITTIVGSSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[180:252](-)"
                     /alternative_weights="1742.0"
                     /alternative_weights="1760.0"
                     /alternative_weights="1778.1"
                     /alternative_weights="1796.1"
                     /alternative_weights="1814.1"
                     /alternative_weights="1832.1"
     CDS             complement(304..423)
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MKEVLVLQQFDEKSEVEPTAWTVTLTTISVTLSTLSNHC"
     CDS             complement(515..2869)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 73.5;
                     E-value: 3.3e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_2"
                     /sec_met_domain="micKC (E-value: 1.5e-130, bitscore: 428.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.3e-18, bitscore: 57.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-09, bitscore: 29.8,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQIIFKHQIPFKHIKDKQSLFNMNSKHGNRTSSGKFIAIYPSSN
                     NMFFRLLNELYEELKHYENGPYILNDKSWKDSNIYYRYGAFKNIYNERGELCIKDENGN
                     LIPDNRQPYYKIPEFVSDFDQYLDSKNNLLDTQDVSNFNDYEFQGVLRFNNGGGIYTGI
                     RKLDGKKVVIKEGRPKVGLDGQFNDAIDRLNIEYEALNKLTDVEGVVNVLDYFKAWKHV
                     FLVEEFVEGVTLQTWCAINYPFNVENDKNEYISKVKKIINSLVKTIKLVHSKDVGMGDL
                     QPQNIMITPESNVKIIDFEAASALSEENGALQTIGYTNKKNKNHKERDWYALKKVLRFC
                     ILPIGPVADIEETIKKKHDMWIEDEFGKDVYQYVVNTENLCDKYLSDTKEKIFKNSYDS
                     KIQKEMDMSKVIKGLRNSIESNILPNSSLIHGDVRQFVMPSGKLNVLTGGTGAALALYR
                     SGNVSKEVWDWIENVLLEKLNVLNDDVGLFTGRAGIAATLYELGYIEQAMDLFNNLSYE
                     DMKDISLRSGLSGIGLSLISLYMEENNNDFLVTSEKIADQIEKRIIEDDKLSVTDFAAV
                     PIGLIDGWSGISLFYAALYSVTKNEKYYLKSKEYIERDLKHCKVDEETNTLQTYDDQNP
                     RLLPYLSGGSIGIGIAIWYLNYVKNNNLFREELEQIINLNKVRIAYSGGLFDGIGSFLL
                     IPPMTKEKNEISQHIELALRKLELFLIRKDDQVLFPGNFSFRLADDYYSGSAGIILGIN
                     SIQFSNPLYWLPIIKIDSFLRKTKKELLLNN"
     CDS             complement(2908..3042)
                     /locus_tag="ctg2_3"
                     /transl_table=11
                     /translation="MQRLIHMKYIIYQITILLVQNTNHHGSFIIIQIIPSKNKAGKYT"
     CDS             complement(3140..4912)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     266.6; E-value: 2.8e-81)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 342.3; E-value:
                     9.1e-104)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MMTNPNFKSKEFFFLLSKTRPNIRLFILAIFLSGLSAIASTLVPH
                     YLKSLIDYYNIHEKINLWDLLGLLGIFLSSGVIGAVGSYMLSVVGYNVVANLRNLLWEK
                     IVILPVEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQ
                     LTLVIVVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISAIRLVKSSTAEKL
                     QVEKGKEDVEALRSIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTF
                     IAFLTLMFYIMGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELAETNKDLV
                     IENLSFCYSNEDKAFSLKNINLIIKRGSVNALVGPSGSGKTTIISILERYYKPNSGNIY
                     FGDENIELFSLNSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPNEKRIVEACKKAYAW
                     QFISELPNSLETNIGEKGLNLSGGQRQRIAIARMFLKNPNIIFLDEATASLDSHSERIV
                     NEAMKKLMKDRTAIIIAHRLSTIINADNIIFMENGEITGQGNHWELKNSHKLYHQFCEQ
                     QFKEDSTDPLVLTN"
     CDS             5367..6749
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 234.1; E-value: 6.3e-71)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_5"
                     /sec_met_domain="Peptidase_S8 (E-value: 4e-44, bitscore:
                     143.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLRRISIVFLFVIVSSLQPVSSRAEESNYDESIIINLDSKISE
                     STINKVQEKYSNIETNYIKELDLLVINNIKPSQFSAIKDIAKEKLDANEIIEDKEISLP
                     DKSKHIPAKVAPSSQFTEGNDTLYDSWLWNIKQVTNDYRSYHINKGSHNTKVGIIDSGI
                     DFNHPDLKKNIVDTGESFVPVEDNTQDFYGHGTSVAGIIAANGDVKGVGPNLGLVPYKV
                     FDKNGKSKRSWVISAIVKATEDDMDVINLSLSTFLSKKDKDDRETIKLFEKAFKFARKH
                     NTLIVAAAGNHGYDISNSKKLAEQLGKPKDNILHLPGGDNDVITVSATTAQNTKASYSN
                     YGKNISIAAPGGDLDTNKIDLYSLVWTTSPVNIPQTPLSKSLGFQKGYEPTLGTSVAAP
                     IVTATAALLKTEYYEKYGEEMPNRKVEENLYQNTDHVENLDKNEVGSGIVNAYESLLNI
                     ER"
     CDS             complement(7212..7388)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MRQLLDWVGQQKGCIRGFCKYDWEWYYKVTPRIKPNKKRKALLIV
                     KRDKECLGLLKKK"
     CDS             complement(8180..9580)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MNQHQKKAPAELKIGQTFPLTIKRLGINGEGVGYFKKKVVFVPGA
                     LPGEEVVAEATNVQPKFSEARVKKIRKPSEHRVTPPCPVYDQCGGCQLQHLAYSQQLRE
                     KRDIVIQSLERHTRFNVEEMNIKETIGMDNPWNYRNKSQFQVGRSQSGSIIAGLYGLDS
                     HKIVPIKECIVQHPATNKTTGIVRRILEKHNVSVYNERTKKGDVRTIVTRVGFETGEVQ
                     VVLVTAKETLPNKDEIVKAIQNRLPEVKSIIQNINGARTSVIFGDKTKALAGSHAIQEV
                     LGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMWVSSGAK
                     EIRGMDVIKESIDDAKKNAKKHGIKNAAYVTGTAEHWLPKWTKEGFRPDVVIVDPPRTG
                     CDGTFLDTIKKVKPKRFVYVSCNPSTLAKDLQALSKDYRVEYIQPVDMFPQTAHVEAVA
                     KLVLKSSN"
     CDS             complement(9753..10616)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MWEETVSVTPPYHFDKVLERLSLDPLNAVDLTARSIKVPLRTRDG
                     KLSVITVQAKGTAIDPVFLVSGETDREEMIERIKHIFQWEQPLQPVLDHFSKTNLSALF
                     EEHAGTPLVLEYDVYNCLMKCIIHQQLNLSFAFTLTERFVHAFGEQKDGVWCYPEPKTI
                     AALEYQDLRELQFSMRKAEYAIDLSRMIADGALNLAELPQLSDEDIMKKLITIRGIGPW
                     TVQNVLMFGLGRPNLFPLADIGLQNAVKRRFALEDKPSKDLMLQVSREWAPYLSYASLY
                     LWRSIE"
     CDS             10837..11682
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MHETELLRDYFHFHPLAIEDCFQHMQRPKIDHYDGYRFYVLHALN
                     PDTLEMEEVDIFQSDRFIVSFHLHESPGISRVRERFFASPGLAKKGPGHITYMIMDQLV
                     DEYFPVLYKIEDRLNEIEDSRTHKSYGTLMNEVFELRTDLLNLRRTIIPMRDLMYRILS
                     LDHVKESRETKAYFSDIYDHLLKLAELIESNRDMTSDLRDSYVTLNSNRMNAIMMTLTI
                     VSTIFIPLTFIAGVYGMNFDNMPELHWKYGYFIVLGVMAALVAAMLFWFARKGWFNIFK
                     "
     CDS             11746..12393
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MCAVTILSHKTISSALLLLSVMSIAPLYNGCTMSDYIFESLGFSS
                     WSEDGAHISVIPGVVLYFAALIWCAASFRRALPAEGLFLIFLSMGVSSSISPVTEYAAF
                     SLKQFAPERKAVEYLKHLSECSHLIERKKASMSCTIYINYYGKGEQTISVTPDLSENVK
                     GVTFKSKTFTVKPRSKTIIKTRFTGFYKGKAASDSGWSSEPDLKVASLHTAE"
ORIGIN
        1 tagtagatgt accgatgagt gttgttagaa gtgtccaccc agctgtttct acttctgaac
       61 ctttactcaa ttgttgcaac tctagtactt cattcatttg ttcatccact cctcttaaat
      121 atcttaacag ttgttgctaa tagtagatga gccaactatc gttgtgatta gtgtaagtaa
      181 gccacctttg ccttttgaag cttctacttc agttccttca ttcagttgtt gaagttccaa
      241 tacatctttc atttagtttc acctcctttc aagtactctt tcttagatta tccttctctc
      301 tcattagcaa tgattactaa gggtagataa tgtaactgaa atagttgtta gagtaacagt
      361 ccatgccgta ggctccactt cagatttttc atcaaattgt tgaagtacca gcacctcttt
      421 cattttcttt tctcacctcc cttcataagt tctgtatatt aactgcttta attctaatct
      481 tcaatgatta tcatcgaata taagtgttag agttttaatt gtttaataac aattcttttt
      541 ttgtctttct taagaaacta tcaattttta ttattggcaa ccaatataac ggatttgaaa
      601 actggataga gtttatgccc aatattatgc cagcacttcc ggagtagtaa tcatctgcta
      661 aacgaaagct gaagtttcca gggaataata cttgatcatc tttgcggata agaaacaatt
      721 ctagttttct caatgccagc tcaatatgct gactgatttc atttttttcc ttagtcattg
      781 gcgggattaa caagaaacta ccgatcccat caaacaatcc accgctatat gcgatcctta
      841 ctttatttaa attgattatt tgctctaatt cttctctaaa taaattatta ttttttacat
      901 aatttaaata ccaaatagca attcctattc cgattgatcc cccagataaa tagggtaata
      961 atcgagggtt ttgatcatca tatgtttgca aagtattcgt ctcttcatct accttacaat
     1021 gttttaaatc tcgctcaata tattcttttg attttaaata atatttttca ttcttagtaa
     1081 ctgaatataa tgccgcatag aataaagata ttcctgacca accatcaatc aaacctatag
     1141 gtactgctgc aaaatcagtc actgataatt tatcatcttc aataatcctt ttttctatct
     1201 gatcagcaat tttttcagaa gtaaccaaaa aatcattatt attttcttcc atgtataagc
     1261 taattaatga aagacctatt cccgacaatc ctgaccttaa tgaaatatct ttcatatctt
     1321 catatgacag attattgaat aagtccatag cttgctctat gtatcccaat tcatacaatg
     1381 ttgctgcgat accagctcgt cctgtaaata acccaacatc atcattaaga acattcaatt
     1441 tttcaagtaa aacattttca atccaatccc aaacttcctt gctgacgttt ccagatctgt
     1501 acaatgccaa tgcagctcca gttcccccag ttagtacatt taactttcca gatggcatta
     1561 caaattgccg tacatcgcca tgaattagcg agctgttggg caaaatatta ctctctatac
     1621 tgtttctcaa tccttttatt acttttgaca tgtccatttc tttttgtatt ttactgtcat
     1681 aactattctt gaatatcttt tctttggtgt cagataagta tttgtcacat agattttctg
     1741 tatttacaac atattgatag acatctttgc caaactcgtc ctctatccac atatcatgtt
     1801 tctttttaat ggtttcttct atatcagcaa ccggacctat tggcagaata caaaatctta
     1861 aaactttctt tagtgcatac caatcacgct ctttatgatt cttatttttc ttatttgtgt
     1921 agccaattgt ttgcaacgct ccgttttctt cagagagagc actagcagcc tcaaaatcaa
     1981 taatcttaac atttgattcg ggggttatca ttatattttg gggttgtaaa tctcccatac
     2041 caacatcttt actatgcact agtttaattg ttttgaccaa gctattaatt atttttttca
     2101 ccttactaat gtattcattt ttatcatttt caacgttgaa cggataattg attgcacacc
     2161 aggtttgaag agttacacct tctacaaact cttcaactaa aaatacatgt ttccaagctt
     2221 taaagtaatc aagtacatta acaacacctt caacatctgt aagtttattt aatgcttcgt
     2281 attctatatt caatctatca atcgcatcat taaattgacc atctaaccct actttaggtc
     2341 ttccttcttt gattactact tttttcccat ccaatttcct tattccagta tatataccgc
     2401 caccattatt aaacctaagg actccttgga actcataatc attaaaatta cttacatctt
     2461 gagtatctaa taagttattc ttggaatcta aatactgatc aaaatcactt acgaattcag
     2521 gtattttata atacggctgt ctattatccg gaattaggtt tccattttcg tctttaatac
     2581 aaagttctcc tctttcattg taaatattct taaacgcacc atatcggtaa tatatattgc
     2641 tgtccttcca cgatttatca tttagtatgt atggtccatt ctcataatgt tttaattctt
     2701 cataaagttc attcaataac ctgaagaaca tgttattaga ggaaggatag atagcgataa
     2761 attttccaga tgaagttcga ttaccatgct tcgaattcat attaaataga gattgtttat
     2821 ctttaatatg tttaaatggt atctgatgtt taaatataat ttgactcaca acttctaata
     2881 tatcctgagc attattcatt gttgcactta cgtgtatttt ccagccttgt tctttgaggg
     2941 tatgatttgg attattataa aacttccatg gtgatttgta ttctgtacta acagtatagt
     3001 aatttggtat attatgtact tcatatggat cagtctctgc atttgggctt ttctctatat
     3061 agtattttga atcttcactc atgtgttgga aataaactaa ttttttgtcc attttgtttt
     3121 cgcctctctt aagccgctct taattggtta atactaatgg atcggtacta tcttctttaa
     3181 actgctgctc acagaattga tgatacaatt tatgactatt ctttaactcc caatgattcc
     3241 cttgacctgt gatctcaccg ttttccataa aaatgatatt gtcagcattt ataatggtgg
     3301 ataacctatg tgctattata atagcggttc tatccttcat aagcttcttc attgcttcgt
     3361 tcacaattcg ttcagaatga ctgtcaagac ttgcagttgc ttcatctaaa aagattatat
     3421 ttggattctt cagaaacatt ctcgcaatag caattctttg tcgttgtcct cctgataagt
     3481 tcagaccttt ttctccaata ttagtttcta aactgttagg caattcactt ataaattgcc
     3541 atgcatatgc cttcttacat gcttctacta ttcttttttc atttggggga ttttctaaac
     3601 caaagatgag attgtctcta atagtaccgc ttattaaatc atgattctgt gctacatatc
     3661 ctatttggct acgccatgaa tttaatgaaa ataactcaat attctcgtca ccaaaataaa
     3721 tatttccgct gttgggcttg tagtatctct ccagaataga gatgattgtg gttttaccac
     3781 taccactagg acctactaag gcattaacac ttcctctttt tattattaaa ttaatatttt
     3841 tcaaggaaaa tgctttatcc tcattactgt agcaaaatga taaattttca atcactaaat
     3901 ctttattggt ttccgctaat tcttttcctt tatgctgatc ttctccttgc tcatatatca
     3961 attgagaaat tctttctgtt gcacctattg tcttttgtat ttgagtaaag aatagcccaa
     4021 agttattaag tggacccatg atatagaaca taagtgtcag aaatgctata aacgttcctg
     4081 gcgataaact tccattggct aatttaaccc ctccgaatcc aattatgcta ataatgataa
     4141 gcatcatcat taaattaatg atagggttta aaataaccat ccattttgtc tgctttaggc
     4201 ctatgcttct taaagcttca acatcttctt ttcctttttc tacttgtaat ttttctgcag
     4261 ttgaagattt aaccagtctt attgcagata ttgtttcaac agctcttaca tttaattcac
     4321 ctgttaagct ttgcgtcatt ttagataatt tagataaaat tcttcctaaa ggtataaaaa
     4381 ttaataaata aactggaatt gctacgacaa tcactagtgt caattgccaa tcatagtaaa
     4441 acaaccaaaa tccacaaaaa agcactatta atatagcatt gataaattgc gaaaaagagt
     4501 tacttactaa gttgtaaatc accgtagtat cattaacaaa tctacttgct atatccgcag
     4561 aacgattctt atcgtaaaat tctacaggca gtataactat cttttcccat aataaatttc
     4621 tgagatttgc gacaacatta tatcctacta cacttaacat ataactacca actgccccaa
     4681 ttactccgct gcttaaaaat atccctagca gtcctaatag gtcccacaaa ttgatctttt
     4741 catgaatatt gtaatagtct attagacttt ttaaataatg aggcactaag gtagaagcta
     4801 ttgcgcttaa tccacttaaa aatattgcca atataaataa tcttatattc ggtctggttt
     4861 tactcagtaa gaagaaaaac tctttcgatt taaaattagg gttggtcatc attttcacct
     4921 ctttcgttta attccaatgt ctcaactttt tatatcgaat gactcttgaa atgacatacg
     4981 ccatatcttt cctgattttc ctataaacaa tatttcacac tcaataactg taagtcaata
     5041 tataatttta caaattataa aaaaacaggt ctttggttat acattattct acttttgtat
     5101 attacgaaat gtatattcac tcttaatatt tctgcccaca aaaccatagg cgtagtataa
     5161 aagaataaaa agaaatttaa attaatcata ctaaagggac gtttccgggg ataatcactt
     5221 ctaattagaa aaatatgcat tgactgattt acttatattt tataaaattg aattaaatat
     5281 acttatattt catttttttg gaatgtgaag ggtgggttat atacaatctt ataatgaaat
     5341 gtataaagag aaaggagtat aaaaaaatga aggatttaag aagaatttcg atagttttct
     5401 tatttgtaat tgtatccagt ttacaacctg ttagctctcg tgctgaagaa tcaaattatg
     5461 atgaatctat cataattaac ctcgactcaa aaattagtga atcgacaata aacaaggttc
     5521 aggaaaagta ttcaaatata gaaacaaatt atattaaaga actagattta ttggtaataa
     5581 ataatataaa accaagccaa ttctcagcaa tcaaagatat tgctaaagaa aaattagacg
     5641 caaatgaaat tattgaggat aaagaaattt ctcttcctga taaaagtaaa catattcctg
     5701 ctaaagtggc accttcatca caattcacgg aaggtaatga cactctttat gacagttggt
     5761 tatggaatat caagcaagtt acaaatgatt atcgaagtta tcatataaat aaaggatctc
     5821 ataatacaaa agtagggata atcgattcag gcatagattt caatcatcca gacctcaaaa
     5881 aaaatattgt agatactgga gagtcttttg ttccagttga agataataca caagactttt
     5941 atgggcatgg aacttctgtg gctggaataa ttgctgctaa tggggatgta aaaggagttg
     6001 gaccaaatct tggtttagtg ccgtataaag tatttgataa aaacggtaaa tctaaaagaa
     6061 gttgggttat aagcgcaatt gttaaagcta cggaagatga tatggacgta attaatttaa
     6121 gtttatctac ttttttatca aaaaaagata aagatgatag agagactata aaactttttg
     6181 aaaaagcttt taaattcgct agaaaacaca atactttaat tgttgcagca gctggaaacc
     6241 atggatatga tatctcaaat tcaaaaaaac ttgcagaaca attaggtaaa ccaaaggaca
     6301 atatcctaca tcttcctggt ggagataacg atgtaattac tgtatctgcc accacagcgc
     6361 aaaatacaaa agcttcttac tcaaattatg gaaaaaacat ctcaattgca gccccaggtg
     6421 gtgatctgga tacaaataag attgatctat atagcttggt atggactact tcccctgtca
     6481 atatcccgca aactccgcta agtaagtcac taggctttca aaagggatat gaacctactt
     6541 tagggacaag tgtagcagct ccaatagtaa ctgctacagc agccctatta aagacagaat
     6601 actacgaaaa atatggagag gaaatgccaa atcgtaaggt tgaagaaaac ttatatcaga
     6661 acacagacca cgttgaaaac ttagataaga atgaagtagg tagcggtatc gtaaatgctt
     6721 acgaatcatt gcttaatatt gagagataaa agatattaag tagttctcga actttcacta
     6781 aaaatacttt gattaataaa aaaagattac tagacgataa tgatgatgaa gtagagatga
     6841 aataaattgt atttacggga tattgagaat aaccaaataa gttgagttca caagcaactt
     6901 aatattacta agttgcttgt gtcatatttt atttcagcct gagtattcaa ttctttagct
     6961 attgttgatt tctttatcgc acaaaaccca gcatgtagca gcaccttata aacagaccaa
     7021 ttctttccct tgctttaatc tatcttcaat agcccactta accttcctta gcctaaatcc
     7081 ctctatacga ttttgtgtac ggactaaatt ttgattacgg gaccatgaac caactcataa
     7141 agttctccta aaatttgcag ggctcactct agttggtttt ctttctgctt ctaaaataat
     7201 tcccgctatt cttacttctt ctttagcagt cccaaacact ctttatccct cttcacaatc
     7261 aacagtgctt ttctcttttt attcggcttt attctcggtg ttactttgta ataccattcc
     7321 caatcatact tacaaaatcc acgtatgcag cccttttgct gtcctaccca atccaacaat
     7381 tgtctcatca aaatagggac agcgatactt gaagcaagta atgtaaacta aaacaagtcg
     7441 ctccaataaa tccaattatc agacctcttt ttatattgct tttcattcaa attcaccctt
     7501 aacaaaccat ttcataatca tagtgaacaa ttagctaatt aagcaaaatg taacgatgcc
     7561 aactattatt aatacatgaa aaaatgcacc tgtcatagga cagttgcaaa ggccttacta
     7621 gaactagagc agcacatgtt gtctacgcta agccaaaaag tggttattac attgttgact
     7681 attatcaaac ccctagtcca attaaagatc atattgattt tatctgctga tccggataaa
     7741 cgcattgcct tatcggcact ttaacattgt atgaatcaag cgatagatca ttataaggag
     7801 caattattca cgtatagtta gcaacagggg ctttactctt taaaaaagga gtttacaaaa
     7861 tattcacagg agttacaagt attcacgaga cttgaacgag tcgttattgc tcttcatatt
     7921 ttgtctgtaa taccgtttcc aaacgaaaaa aagaatatgt ttatggagca gcatgataga
     7981 actttactgt tgaatcatgt tacagcttta ggaattgatc taaaaaatga gggtttccgc
     8041 acgttttttc agctcttttc gtcagtgaaa ataaagttct ctgagaaaag acagtcaggg
     8101 caaaggctcc ctatgaaaaa gacccggaaa tcggcaaggt tcattctgcc gaaatccaga
     8161 tctgatcagg aatcgttttt taattagacg atttcaatac aagcttcgcc acagcttcca
     8221 catgagccgt ctgcggaaac atatccacag gctgaatata ttcgacgcga tagtccttcg
     8281 acagcgcctg caagtctttc gccagtgtgg aaggattgca ggatacgtag acgaagcgtt
     8341 tcggttttac ttttttgatg gtatctaaaa atgttccgtc gcagcccgtt ctcggcgggt
     8401 cgacgatgac cacgtctggg cggaagcctt ctttcgtcca tttcgggagc cagtgttcag
     8461 ctgttcctgt gacatatgcc gcgtttttga tgccgtgttt tttggcgttc ttcttcgcat
     8521 cgtcaattga ttctttaatg acgtccatgc cgcggatctc tttcgccccg cttgagaccc
     8581 acatgccgat cgtaccgacg ccgcaatatg cgtcaacgac tttttctttt ccggtcagct
     8641 gcgccgcttt tttcacttcg tcatacagct tgaccgtctg ctcagggttg agctggaaga
     8701 aagcgcgggc gcttaattca aatgacacgt caccaagtac ctcttgaatg gcatggcttc
     8761 cggccagcgc ttttgttttg tccccgaaaa tgacggatgt gcgcgcgccg ttgatgtttt
     8821 gaataatcga tttcacttcg ggcagacgat tctgaatggc tttgacgatc tcgtctttat
     8881 tcggaagtgt ctctttcgcc gtgacaagca cgacctgcac ttcgcctgtt tcaaaaccga
     8941 ctctcgtcac gatggtgcgg acatcgcctt ttttggtccg ttcgttataa acagatacgt
     9001 tgtgtttttc caatatgcgg cggacaatac ccgttgtttt gttcgtcgcc ggatgctgga
     9061 caatgcattc cttaatcgga acaattttat gggaatcaag tccgtataag ccggcaatga
     9121 tgctgccgct ttgcgagcgt ccgacttgaa actggctttt gttccggtaa ttccacgggt
     9181 tgtccattcc gatcgtttct ttaatgttca tttcttcaac attgaatctc gtatgacgtt
     9241 ccaaagactg aatgacgata tcgcgctttt cgcgaagctg ctgactgtag gccagatgct
     9301 gaagctggca gccgccgcat tgatcgtata ccggacaagg cggcgtgacg cggtgttcag
     9361 acggcttgcg gatttttttg acgcgtgctt ctgaaaattt cggctgaacg tttgtcgctt
     9421 cggcaacgac ttcttcgccg ggcagagcgc cgggaacgaa gacaaccttt ttcttaaaat
     9481 agccgacgcc ctctccatta atgccgaggc gtttgatggt cagcggaaat gtctgtccga
     9541 ttttcaattc ggcaggcgcc tttttttgat gttgattcac gttttattct ctccgtttct
     9601 ataataaagc catcctcatg ggaaaacggc tgatttgaaa tatcacatct tttcagtata
     9661 acatgcagcc ggcggttcct tcatgttttt caccggaagt ttccaaaaaa tactcggaag
     9721 cgatcaaatg ccatcggtaa gccatcttgt ttttattcaa tacttctcca caaatacaag
     9781 gacgcgtagc ttaaatacgg cgcccattcc ctgcttactt gaagcatcaa gtcttttgac
     9841 ggtttatcct caagggcgaa gcggcgtttg acggcgtttt gcaggccgat atctgccaaa
     9901 ggaaacagat tcgggcggcc gaggccgaac atgaggacgt tttggacggt ccatggcccg
     9961 atgcctctga tggtgatcag ctttttcata atgtcttcat ccgataactg gggaagttcc
    10021 gcaagattga gcgctccgtc tgcaatcatc cgtgaaaggt caatcgcata ttccgctttt
    10081 ctcatgctga actgaagctc ccgcaagtcc tgatactcaa gcgccgcaat cgttttcggc
    10141 tcggggtagc accagacgcc gtctttttgt tcgccgaagg catggacgaa ccgttccgtt
    10201 aaggtaaaag cgaaggacag gttgagctgc tggtggatga tgcatttcat gagacagttg
    10261 tacacatcgt attccagcac gagcggggtt cccgcatgct cttcaaaaag cgcagacaga
    10321 tttgtttttg aaaaatgatc aagcacaggc tgaagcggct gctcccactg aaaaatgtgt
    10381 ttgatccgtt caatcatctc ctcgcggtcc gtttcgccgc tgacgaggaa aaccggatct
    10441 atggcggtgc ctttcgcttg aaccgtgatg accgacagtt tgccgtcccg tgttctgagc
    10501 ggaactttaa ttgaccttgc tgtaagatcg accgcattca gcggatcgag tgacagcctt
    10561 tcaagcactt tatcaaaatg atacggcggc gtgaccgaaa ccgtttcctc ccacatatgc
    10621 tccacccctt tttgtccaag tatatcacga agcgttccga cggcaattcg tatacttttc
    10681 ttcataacgc cgcatgatat aatggcaggc ggagggttgt ttatgataca tataaccgca
    10741 atcacaacac ataatgagat attagataat atccccctat cacgtacaga acaaccggac
    10801 atcgcatggt actggattga ttttttcgga gccgagatgc atgaaaccga gctgctgcgg
    10861 gattatttcc attttcatcc gctcgcgatt gaggattgct ttcagcacat gcagcggccg
    10921 aaaatcgacc attatgacgg ctaccgtttt tatgtgctcc acgccttgaa cccggacaca
    10981 ctggaaatgg aagaggtgga catttttcag tccgaccgtt tcatcgtcag cttccatctg
    11041 cacgaatcgc ccggcatctc gagagtaaga gaacggtttt tcgcttctcc ggggttagcc
    11101 aaaaaagggc ccggacacat aacgtatatg attatggatc agcttgtcga tgaatatttc
    11161 cctgtgctgt acaaaattga agaccggctg aatgaaattg aagacagcag aacacataaa
    11221 tcttacggca ctttaatgaa tgaagtgttt gaattgcgga ctgatctttt gaacctgagg
    11281 cggacgatca ttccgatgcg cgatttaatg taccggattt tgagtcttga ccatgtaaaa
    11341 gaaagccgtg aaacaaaagc atatttcagc gatatttacg accacctgtt aaaactggct
    11401 gagctgatcg agtcaaaccg tgatatgacg tcagatctgc gggacagcta tgtgacgctg
    11461 aattcaaacc ggatgaacgc catcatgatg acgttaacca tcgtctcgac catttttatt
    11521 ccgctcacat tcatcgcggg agtttacggc atgaatttcg ataacatgcc tgagcttcat
    11581 tggaaatacg ggtattttat cgttttgggc gtaatggccg ctcttgtggc cgccatgctg
    11641 ttttggttcg cccggaaagg ctggtttaat attttcaagt aagaacggct gccggctgtt
    11701 cttttttttg tgaaaacatg atatgttgga aaaaaacgta aagaggtgtg cgccgttacc
    11761 attctttctc acaaaaccat ttcttccgcc cttctgcttc tcagtgtcat gtccattgcc
    11821 ccgctgtata acggctgtac gatgtctgat tacatctttg agtcgctcgg cttttcttct
    11881 tggtctgaag atggagccca tatctccgtc attcccgggg ttgtgctata ctttgcggcg
    11941 ttaatctggt gtgccgcctc gttcagacgg gcgcttcccg ctgaggggct gtttctgatc
    12001 tttctcagca tgggggtctc ttccagcatc agtcctgtca ctgaatatgc cgctttttcc
    12061 ttaaaacagt tcgcgcctga aagaaaggct gtcgaatatc tgaagcacct cagtgaatgc
    12121 agtcatctga ttgagcgcaa aaaagcgagc atgagctgca cgatttatat caattattat
    12181 ggaaaagggg aacaaaccat atctgtcaca cctgatctat ctgagaacgt aaagggcgtc
    12241 acatttaaat caaaaacatt cactgtaaag ccccggtcga aaacaatcat caagacgcgt
    12301 tttaccggct tttataaagg gaaagccgca tcagacagcg gatggtcttc agaacctgac
    12361 ctaaaagttg caagcctgca cacagcagaa taaacgtttt gcatgtataa cgatggaaaa
    12421 catttcattg gagggtctgc taatgaagat cgccatcgtc ggactcggca atatgggacg
    12481 ccccatcgcc gaaaatataa tgaaagccgg atacagtctg actgtctata accggacgaa
    12541 agaaaaagcg gctgatctgc tggagaaagg ggccgaatat gccaaaacgc cccgtcaggc
    12601 agctgaacat gcggacattg tgctgtcaat gctgtcggac gatgaagccg taacaggtgt
    12661 gactttcggg gctgacggca ttattgccgg gttatctgaa aacgacattc atatttcaat
    12721 gagcaccatc agcacggcgc tgtcagaaca gctttccgct gcgcattcga gcagaggaca
    12781 gtcctttatt gccgctcccg tcctcggccg tcccgatgcg gctgagaagg ccgagctccg
    12841 catcatcaca gccggtcctc aggaagcga
//
