LOCUS       gnlProkkaAAKNCBCF_18   28309 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AAKNCBCF_18.
ACCESSION   gnlProkkaAAKNCBCF_18
VERSION     gnlProkkaAAKNCBCF_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 19:42:34
            Original ID  :: gnl|Prokka|AAKNCBCF_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28309
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..28309
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:8309]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..8309
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..28309
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..28309
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="betalactone"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     protocluster    1..26476
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4490:16476]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      4491..16476
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     aSDomain        2..769
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-96"
                     /label="ctg18_1_Condensation_LCL.1"
                     /locus_tag="ctg18_1"
                     /protein_end="256"
                     /protein_start="0"
                     /score="315.1"
                     /tool="antismash"
                     /translation="MEGKLNPERMDRAFQELIKRHESLRTSFEQDEGGDPVQRIHDEVP
                     FTLQTTVLGARTEQEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVS
                     VNILIQEFGELYNNRKLPALRIQYKDYAVWQEGFKTGDAYKMQEAYWLKQLEGELPVLD
                     LPADHARPPVRSFAGDKVSFTLEPEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQ
                     EDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRP"
     aSModule        2..4438
                     /complete
                     /domains="nrpspksdomains_ctg18_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg18_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg18_1_PCP.1"
                     /domains="nrpspksdomains_ctg18_1_Epimerization.1"
                     /domains="nrpspksdomains_ctg18_1_TIGR01720.1"
                     /locus_tags="ctg18_1"
                     /monomer_pairings="Tyr -> D-Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS             2..4462
                     /NRPS_PKS="Domain: Condensation_LCL (0-256). E-value:
                     1.2e-96. Score: 315.1. Matches aSDomain:
                     nrpspksdomains_ctg18_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (421-815). E-value:
                     1.2e-112. Score: 368.4. Matches aSDomain:
                     nrpspksdomains_ctg18_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (922-989). E-value: 2.2e-27. Score:
                     87.0. Matches aSDomain: nrpspksdomains_ctg18_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (999-1311). E-value:
                     1.9e-154. Score: 507.2. Matches aSDomain:
                     nrpspksdomains_ctg18_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1323-1479). E-value: 8.3e-46.
                     Score: 147.5. Matches aSDomain:
                     nrpspksdomains_ctg18_1_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     369.3; E-value: 4.3e-112)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="Condensation (E-value: 7.3e-86, bitscore:
                     280.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-123, bitscore:
                     404.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore:
                     53.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGKLNPERMDRAFQELIKRHESLRTSFEQDEGGDPVQRIHDEVP
                     FTLQTTVLGARTEQEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVS
                     VNILIQEFGELYNNRKLPALRIQYKDYAVWQEGFKTGDAYKMQEAYWLKQLEGELPVLD
                     LPADHARPPVRSFAGDKVSFTLEPEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQ
                     EDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQN
                     YPFEELVDKLELTRDMSRNPVFDAMLVVQNNDYEPLHLHDLQMKPAQVSHLVSKFDLTL
                     QASEGDGNIHFLFEYSTALFEKTTIERWASHLTNVLSIIGKNPKVTLNHIDILTQEERH
                     QLLNEFNTGQANQYGVQTISQLFEQQAARTPKASALVSGDKTLTYQELDEWSNGIARAL
                     RSRGVKPDTPVGIMMHRSFSMIASILGVWKAGGCYVPIDPEYPKERKRYILSDSGTKLL
                     MTINEADLGVLADFEGEILTIESVEEDDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMV
                     EHKGIANTLQWRRNAYAFNETDTILQLFSFSFDGFITSMFTPLLSGAKAVLLHEEEAKD
                     ILAIKHQLSRQRITHMIIVPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIARSLAI
                     CPHTELANEYGPTENSVATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGE
                     LCIAGTGLARGYVNLPELTERAFTQNPFKPEARMYRTGDAARWMADGTLEYLGRIDDQV
                     KIRGYRVETKEIESVIRCIKGVKDAAVVAHVTASGQTELSAYVVTKPGLSTNAVRSELQ
                     NKLPVFMHPAFIEKLDSLPLSPNGKLDRGALPKPVYNHEGERPFLPPSSKMEQILADIW
                     KEVLGAEKIGTADSFFELGGDSIKALQVSARLHRIGKQMAVKDLFSHPTIQELAAYIRD
                     SDTSSSQAAVEGDVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTLKAIT
                     CHHDALRMVFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLSAPDGTDGNRPYEPLIKRH
                     VLDIQQKMDLKNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYRQAAG
                     GEDIKLPPKTSSFKAYAKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDQIDGTRAHE
                     GQRSTISFTLNDKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSLEGHG
                     REDVLKGIDVSRTIGWFTAIYPLLIKLNADLPDSEESMVHVLKTTKDTLRRVPDKGFGY
                     GVIKYLTPPGKKDINFTGAPEISFNYLGQFESGRTAEVPEEDAFSFSPLGAGGDISTTW
                     NREQSLDISAIAAEGKLTVNMTYDNARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEK
                     TISDFDDQELTEDALQEIADMLSFH"
     CDS_motif       5..85
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0001"
                     /evalue="1.30E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg18_1"
                     /protein_end="28"
                     /protein_start="1"
                     /score="36.9"
                     /tool="antismash"
                     /translation="EGKLNPERMDRAFQELIKRHESLRTSF"
     CDS_motif       284..349
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0002"
                     /evalue="7.20E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg18_1"
                     /protein_end="116"
                     /protein_start="94"
                     /score="31.3"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIQEFGELY"
     CDS_motif       380..409
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0003"
                     /evalue="1.40E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg18_1"
                     /protein_end="136"
                     /protein_start="126"
                     /score="14.5"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       671..760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0004"
                     /evalue="1.70E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg18_1"
                     /protein_end="253"
                     /protein_start="223"
                     /score="49.3"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       809..925
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0005"
                     /evalue="5.30E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg18_1"
                     /protein_end="308"
                     /protein_start="269"
                     /score="60.6"
                     /tool="antismash"
                     /translation="RETALEAFEHQNYPFEELVDKLELTRDMSRNPVFDAMLV"
     aSDomain        1265..2446
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_AMP-binding.1"
                     /evalue="1.20E-112"
                     /label="ctg18_1_AMP-binding.1"
                     /locus_tag="ctg18_1"
                     /protein_end="815"
                     /protein_start="421"
                     /score="368.4"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="FEQQAARTPKASALVSGDKTLTYQELDEWSNGIARALRSRGVKPD
                     TPVGIMMHRSFSMIASILGVWKAGGCYVPIDPEYPKERKRYILSDSGTKLLMTINEADL
                     GVLADFEGEILTIESVEEDDKSPLPQMSSAHHLAYIIYTSGTTGRPKGVMVEHKGIANT
                     LQWRRNAYAFNETDTILQLFSFSFDGFITSMFTPLLSGAKAVLLHEEEAKDILAIKHQL
                     SRQRITHMIIVPVLYRALLDVVQPEDVKTLRVVTLAGEAADRELIARSLAICPHTELAN
                     EYGPTENSVATTVMRHMEKQAYVSIGQPIDGTQVLILNSNHQLQPIGVAGELCIAGTGL
                     ARGYVNLPELTERAFTQNPFKPEARMYRTGDAARWMADGTLEYLGRIDDQVKIR"
     CDS_motif       1451..1492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0006"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg18_1"
                     /protein_end="497"
                     /protein_start="483"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGVWKAGGCYVPID"
     CDS_motif       1676..1735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0007"
                     /evalue="3.60E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg18_1"
                     /protein_end="578"
                     /protein_start="558"
                     /score="34.7"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGRPKGVMVEH"
     CDS_motif       2240..2329
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0008"
                     /evalue="3.30E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg18_1"
                     /protein_end="776"
                     /protein_start="746"
                     /score="48.1"
                     /tool="antismash"
                     /translation="PIGVAGELCIAGTGLARGYVNLPELTERAF"
     CDS_motif       2411..2476
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0009"
                     /evalue="4.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg18_1"
                     /protein_end="825"
                     /protein_start="803"
                     /score="34.8"
                     /tool="antismash"
                     /translation="YLGRIDDQVKIRGYRVETKEIE"
     aSDomain        2768..2968
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_PCP.1"
                     /evalue="2.20E-27"
                     /label="ctg18_1_PCP.1"
                     /locus_tag="ctg18_1"
                     /protein_end="989"
                     /protein_start="922"
                     /score="87.0"
                     /tool="antismash"
                     /translation="EQILADIWKEVLGAEKIGTADSFFELGGDSIKALQVSARLHRIGK
                     QMAVKDLFSHPTIQELAAYIRD"
     aSDomain        2999..3934
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_Epimerization.1"
                     /evalue="1.90E-154"
                     /label="ctg18_1_Epimerization.1"
                     /locus_tag="ctg18_1"
                     /protein_end="1311"
                     /protein_start="999"
                     /score="507.2"
                     /tool="antismash"
                     /translation="EGDVQWSPVQKWFLSQDIKEKHHFNQSVMLHRSTSVQEDALRKTL
                     KAITCHHDALRMVFTQNEQGKWDQYNRPLSHSDDALYGLQMIDLSAPDGTDGNRPYEPL
                     IKRHVLDIQQKMDLKNGPLLQAGLFHTIDGDFLFLSAHHLVVDGISWRVLLEDLALGYR
                     QAAGGEDIKLPPKTSSFKAYAKKLSDYAESQQLMKQLKYWREAEEYQTEALPFDQIDGT
                     RAHEGQRSTISFTLNDKETAALLKDANSAYNTDTQDMLLASVILALRHWTNQSAFKLSL
                     EGHGREDVLKGIDVSRTIGWFTAIYPLLIKL"
     CDS_motif       3149..3190
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0010"
                     /evalue="1.30E-03"
                     /label="Cy2"
                     /locus_tag="ctg18_1"
                     /protein_end="1063"
                     /protein_start="1049"
                     /score="11.5"
                     /tool="antismash"
                     /translation="HHDALRMVFTQNEQ"
     CDS_motif       3407..3472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0011"
                     /evalue="2.70E-11"
                     /label="NRPS-E2"
                     /locus_tag="ctg18_1"
                     /protein_end="1157"
                     /protein_start="1135"
                     /score="35.6"
                     /tool="antismash"
                     /translation="LFLSAHHLVVDGISWRVLLEDL"
     CDS_motif       3878..3925
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0012"
                     /evalue="6.10E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg18_1"
                     /protein_end="1308"
                     /protein_start="1292"
                     /score="24.8"
                     /tool="antismash"
                     /translation="DVSRTIGWFTAIYPLL"
     aSDomain        3971..4438
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_1_TIGR01720.1"
                     /evalue="8.30E-46"
                     /label="ctg18_1_TIGR01720.1"
                     /locus_tag="ctg18_1"
                     /protein_end="1479"
                     /protein_start="1323"
                     /score="147.5"
                     /tool="antismash"
                     /translation="HVLKTTKDTLRRVPDKGFGYGVIKYLTPPGKKDINFTGAPEISFN
                     YLGQFESGRTAEVPEEDAFSFSPLGAGGDISTTWNREQSLDISAIAAEGKLTVNMTYDN
                     ARFQRKTIEQLSETCRQFLLQLIEHCQNKSETEKTISDFDDQELTEDALQEI"
     CDS_motif       3986..4048
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0013"
                     /evalue="1.20E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg18_1"
                     /protein_end="1349"
                     /protein_start="1328"
                     /score="30.3"
                     /tool="antismash"
                     /translation="TKDTLRRVPDKGFGYGVIKYL"
     CDS_motif       4088..4117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_1_0014"
                     /evalue="4.90E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg18_1"
                     /protein_end="1372"
                     /protein_start="1362"
                     /score="9.5"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     CDS             4491..8309
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (1-29). E-value: 3.5e-15.
                     Score: 46.9. Matches aSDomain:
                     nrpspksdomains_ctg18_2_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (8-309). E-value:
                     2.4e-119. Score: 389.8. Matches aSDomain:
                     nrpspksdomains_ctg18_2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (474-867). E-value:
                     2.1e-110. Score: 361.0. Matches aSDomain:
                     nrpspksdomains_ctg18_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (973-1040). E-value: 7.5e-23. Score:
                     72.4. Matches aSDomain: nrpspksdomains_ctg18_2_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1060-1264). E-value:
                     3.8e-41. Score: 133.8. Matches aSDomain:
                     nrpspksdomains_ctg18_2_Thioesterase.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     340.5; E-value: 2.3e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="Condensation (E-value: 4.2e-90, bitscore:
                     294.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-114, bitscore:
                     374.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.2e-17, bitscore:
                     54.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSL
                     SYDWFQRSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLNSEDISHLPTNDQN
                     EYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFM
                     QIYQSIHAGKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSAPSPLPRVSDKE
                     TKESYHREDLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAV
                     VSGRPSEIPGVEQMIGLFINTIPIRIKTHQDETFHELLIRCQKEMLEAEPFTCQPLFDI
                     QANTALKQELIDHIIVFENYPLQQKIADSADQTDSPLQIDQVQVSEQSGYNFNLVVAPG
                     EELVIKFSYNAFVYDAAWISCIKRQFTQALSTAAQHPHMPIADFSFLDATEKEQIVTQF
                     NNTKTEYPKNHTIIDLFREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFR
                     KNETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVSFMLEETQAKMLIVQKGL
                     EQNAAFSGTCIISDAQGLMEENDIPINISSSPDDLAYIMYTSGSTGRPKGVMITNRNVV
                     SLVRNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLNGASLHIIDKSTMLTPDRFGAY
                     LLENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHN
                     IYGPTENTTFSTFFEMKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDG
                     VAKGYLNRVDLTNAVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIRGKRI
                     EPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYVGDHKKTDTDFRADLARVLPDYMI
                     PQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQNIILPRNLVEEELANIWKQVLGVNT
                     ISIDDDFFAIGGHSLRALQVIHTLKHQQNIDIPIDFLFEHPTIAQLAEKLYSKQLTAAN
                     EQHVIKLNQHGAQNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYVNC
                     MTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGNDE
                     SAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIHPETSGHTGLTKWEG
                     ACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITSNQVILHKR"
     aSDomain        4494..4577
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_2_NRPS-COM_Nterm.1"
                     /evalue="3.50E-15"
                     /label="ctg18_2_NRPS-COM_Nterm.1"
                     /locus_tag="ctg18_2"
                     /protein_end="29"
                     /protein_start="1"
                     /score="46.9"
                     /tool="antismash"
                     /translation="NTIKKIKNIYPLSHMQEGMLFHSFLRKE"
     aSDomain        4515..5417
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.40E-119"
                     /label="ctg18_2_Condensation_DCL.1"
                     /locus_tag="ctg18_2"
                     /protein_end="309"
                     /protein_start="8"
                     /score="389.8"
                     /tool="antismash"
                     /translation="NIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSLSYDWFQRS
                     IQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLNSEDISHLPTNDQNEYIERFKE
                     KDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHA
                     GKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSAPSPLPRVSDKETKESYHRE
                     DLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEI
                     PGVEQMIGLFINTIPIRIKT"
     aSModule        4515..8282
                     /complete
                     /domains="nrpspksdomains_ctg18_2_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg18_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg18_2_PCP.1"
                     /domains="nrpspksdomains_ctg18_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg18_2"
                     /monomer_pairings="Ile -> Ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4521..4562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0001"
                     /evalue="3.90E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg18_2"
                     /protein_end="24"
                     /protein_start="10"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YPLSHMQEGMLFHS"
     CDS_motif       4581..4697
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0002"
                     /evalue="1.20E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg18_2"
                     /protein_end="69"
                     /protein_start="30"
                     /score="49.7"
                     /tool="antismash"
                     /translation="GAYVEQSLFTIKGSLSYDWFQRSIQAIIDRHDIFRTVFL"
     CDS_motif       4923..4988
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0003"
                     /evalue="1.00E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg18_2"
                     /protein_end="166"
                     /protein_start="144"
                     /score="40.4"
                     /tool="antismash"
                     /translation="HHHILMDGWCLGIVMQEFMQIY"
     CDS_motif       5313..5408
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0004"
                     /evalue="1.30E-21"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg18_2"
                     /protein_end="306"
                     /protein_start="274"
                     /score="69.0"
                     /tool="antismash"
                     /translation="DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIR"
     CDS_motif       5457..5573
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0005"
                     /evalue="1.40E-16"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg18_2"
                     /protein_end="361"
                     /protein_start="322"
                     /score="52.9"
                     /tool="antismash"
                     /translation="QKEMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYP"
     aSDomain        5913..7091
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_2_AMP-binding.1"
                     /evalue="2.10E-110"
                     /label="ctg18_2_AMP-binding.1"
                     /locus_tag="ctg18_2"
                     /protein_end="867"
                     /protein_start="474"
                     /score="361.0"
                     /specificity="substrate consensus: Ile"
                     /tool="antismash"
                     /translation="FREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFRKN
                     ETAGILAAHSPEFMISVLAVLKAGGAYLPLDAELPPERVSFMLEETQAKMLIVQKGLEQ
                     NAAFSGTCIISDAQGLMEENDIPINISSSPDDLAYIMYTSGSTGRPKGVMITNRNVVSL
                     VRNSNYTSASGDDRFIMTGSISFDAVTFEMFGALLNGASLHIIDKSTMLTPDRFGAYLL
                     ENDITVLFLTTALFNQLAQVRADMFRGLHTLYVGGEALSPALMNAVRHACPDLALHNIY
                     GPTENTTFSTFFEMKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDGVA
                     KGYLNRVDLTNAVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIR"
     CDS_motif       6099..6140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0006"
                     /evalue="8.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg18_2"
                     /protein_end="550"
                     /protein_start="536"
                     /score="18.9"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       6324..6380
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0007"
                     /evalue="4.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg18_2"
                     /protein_end="630"
                     /protein_start="611"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGRPKGVMIT"
     CDS_motif       6885..6974
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0008"
                     /evalue="3.80E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg18_2"
                     /protein_end="828"
                     /protein_start="798"
                     /score="47.9"
                     /tool="antismash"
                     /translation="PIGVPGELCVGGDGVAKGYLNRVDLTNAVF"
     CDS_motif       7056..7121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0009"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg18_2"
                     /protein_end="877"
                     /protein_start="855"
                     /score="30.2"
                     /tool="antismash"
                     /translation="YISRIDRQMKIRGKRIEPAEIE"
     aSDomain        7410..7610
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_2_PCP.1"
                     /evalue="7.50E-23"
                     /label="ctg18_2_PCP.1"
                     /locus_tag="ctg18_2"
                     /protein_end="1040"
                     /protein_start="973"
                     /score="72.4"
                     /tool="antismash"
                     /translation="EEELANIWKQVLGVNTISIDDDFFAIGGHSLRALQVIHTLKHQQN
                     IDIPIDFLFEHPTIAQLAEKLY"
     aSDomain        7671..8282
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_2_Thioesterase.1"
                     /evalue="3.80E-41"
                     /label="ctg18_2_Thioesterase.1"
                     /locus_tag="ctg18_2"
                     /protein_end="1264"
                     /protein_start="1060"
                     /score="133.8"
                     /tool="antismash"
                     /translation="QNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYV
                     NCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGN
                     DESAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIHPETSGHTGLTKW
                     EGACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITS"
     CDS_motif       7824..7895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_2_0010"
                     /evalue="3.10E-13"
                     /label="NRPS-te1"
                     /locus_tag="ctg18_2"
                     /protein_end="1135"
                     /protein_start="1111"
                     /score="42.0"
                     /tool="antismash"
                     /translation="QPEGPYVLLGYSAGGNLAFEVAQA"
     CDS             8420..8812
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MDRLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRIVDQ
                     NGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQAIL
                     ETAVGVGVKLIDVLKSLQTMMNDKKS"
     CDS             8948..10480
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASVL
                     NIDWPSKKGLSVKEQKQEYIKLLDDVQKMGMNAVIVQIKPTADAFYPSAYGPWSEYLTG
                     VQGKDPGYDPLAFMIEETHKRNLEFHAWFNPYRITMNHTDLNKLSEDHPARKHPDWVAA
                     YGNQLYYHPGIPEARDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQYEQY
                     GKDAFSNIDDWRRDNVNQLVKQINQTIKAAKPYVKFGISPFGVWRNAADDPTGSNTKAG
                     VRNYDDLYADTRHWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRPVHLYIG
                     QAAYKINNNFDPPWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLGIKDSLSTDL
                     YSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNQKTKETAYYAIYRAEG
                     KKQRTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRTTK"
     CDS             11147..12289
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 459.4; E-value:
                     1.6e-139)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.3e-40, bitscore:
                     129.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-28, bitscore:
                     91.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.4e-56, bitscore:
                     181.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFKKM
                     GELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTE
                     EQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYA
                     RTVIVTAVTGKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPA
                     ANLLGDPTKGFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPISSFQA
                     IQFKLADMAMEIDLARQMVLKAAWLKDHNRPFTKEAAYAKLFASEMATRACNQAIQIHG
                     GSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK"
     CDS             12333..13982
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 9.5e-105.
                     Score: 342.3. Matches aSDomain:
                     nrpspksdomains_ctg18_6_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     456.8; E-value: 1.3e-138)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_6"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-115, bitscore:
                     377.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCR
                     QTAKGLMRMGIGKGDHVAIWASNISEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQ
                     SDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLSGMY
                     HWDDTEILAKTVTDAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANI
                     AECMALTSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCT
                     VLHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQ
                     TEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVM
                     KGYYKDKDATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEF
                     LYQHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDELKAYCKGKIARHKIPRYVI
                     FTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ"
     aSDomain        12372..13667
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_6_AMP-binding.1"
                     /evalue="9.50E-105"
                     /label="ctg18_6_AMP-binding.1"
                     /locus_tag="ctg18_6"
                     /protein_end="445"
                     /protein_start="13"
                     /score="342.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGK
                     GDHVAIWASNISEWLAVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYR
                     GTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLSGMYHWDDTEILAKTVT
                     DAELEERMNSLDKDNVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMALTSQDRMC
                     IPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTVLHGVPTMFIAEL
                     HHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRAN
                     DSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVMKGYYKDKDATRKA
                     INHDGWLFTGDLAVMDEDGYCRITGRLKDMLIR"
     CDS_motif       12918..12968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_6_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg18_6"
                     /protein_end="212"
                     /protein_start="195"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS_motif       13488..13565
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_6_0002"
                     /evalue="5.00E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg18_6"
                     /protein_end="411"
                     /protein_start="385"
                     /score="12.5"
                     /tool="antismash"
                     /translation="GMQGELCTRGYHVMKGYYKDKDATRK"
     CDS             13992..15326
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     656.4; E-value: 9e-199)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.6e-17,
                     bitscore: 55.2, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.2e-10, bitscore:
                     32.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDAPHTKAA
                     TEAYLIGESRVSESYLNIERIIKTAKKAKADAIHPGYGLLSENSRFAERCKQENIVFIG
                     PSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTASQIGYPVMLKASAGG
                     GGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTV
                     HLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEFIVDQK
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHAIEVRIY
                     AEDPKTFFPSPGTITAFSLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAI
                     EKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL"
     CDS             15341..15562
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADRS
                     GIVKEVKKKEGDFVNEGDVLLELSNSTQ"
     CDS             15577..16476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 266.8;
                     E-value: 6.3e-81)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_9"
                     /sec_met_domain="HMGL-like (E-value: 1.3e-50, bitscore:
                     164.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYI
                     EITSFVHPKWIPALRDAIDVAKGIDREKGVTYAALVPNQRGLENALEGGINEACVFMSA
                     SETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVIRLS
                     EALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTA
                     LQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIE
                     EKMGKPLPSRNLQVFKSS"
     CDS             16497..17279
                     /NRPS_PKS="Domain: ECH (10-252). E-value: 2.2e-69. Score:
                     225.3. Matches aSDomain: nrpspksdomains_ctg18_10_ECH.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 263.3; E-value:
                     2.8e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MGDSILFTVKNEHMALITLNRPQAANALSAEMLRNLQMIIQEIEF
                     NSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAI
                     NGSALGGGLELALACDLRIATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIY
                     TGRRVTAHEAKEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDL
                     ATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI"
     aSDomain        16527..17252
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_10_ECH.1"
                     /evalue="2.20E-69"
                     /label="ctg18_10_ECH.1"
                     /locus_tag="ctg18_10"
                     /protein_end="252"
                     /protein_start="10"
                     /score="225.3"
                     /tool="antismash"
                     /translation="NEHMALITLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILT
                     GTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLE
                     LALACDLRIATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEA
                     KEIGLVEHVTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKA
                     YEQTIPTKDRREGLQAFQEK"
     CDS             17296..18825
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 544.9; E-value: 3.6e-165)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDD
                     IELEDAFFAECMSDGLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQ
                     EIAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSA
                     AGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDIL
                     AETEEEAIQLVRAYLSYFPANFQEKAPIHEKRPPKHFETPLADVIPQNQNAPFDMHELI
                     ERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFIT
                     LCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAG
                     LYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREEYK
                     EDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV"
     CDS             18995..20194
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEIRYNSVNGLNAQVQYFL
                     EKAKESNRQDALFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFVQV
                     EYDDGRLTSATSLLYGYLIENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRLNDL
                     FFLLSIDEFEAKMIQRLSTHDEFFFDDFEEKLLDLEDEKIERYLRRKKREMVQTFVHEH
                     CVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDYIDVSEIAGRYGGG
                     GHAKASGCSITDEVYELFVAEAFRIDPVRPDAFRNIYNLKGSANGSLYENRAQMRFFLF
                     PLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLKLANQHRK
                     "
     CDS             complement(20243..20839)
                     /gene_functions="other (smcogs) SMCOG1188:hypothetical
                     protein (Score: 144.2; E-value: 4.6e-44)"
                     /gene_kind="other"
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MGSLISEILTWLTNMGYAGIAIGLMIEIIPSEIVLAYGGYMVSEG
                     TIGFIGAIIAGVIGGTIAQIFIYWIGRYGGRPFLDKYGKYLLIKKHHIDMSENWFQKYG
                     AGVVFSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQWDD
                     VENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR"
     CDS             complement(20912..21805)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 231.4; E-value:
                     2.2e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_14"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.1e-11, bitscore:
                     36.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEE
                     AAESGIEDILIITGRNKRSIEDHFDRSAELEFNLREKGKTETLKEMQQIADLANIHYIR
                     QKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSV
                     LPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIG
                     RGAGNEIQLTDALREVCRKEPIHARLLEGNRYDIGDKLGCFKASTEIGLMRPEMRSQLL
                     AYLEDVIKRETKEMLR"
     CDS             22853..24394
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MRKKCSVCLWILVLLLSCLSGKSAYAATSTTIAKHIGNSNPLIDH
                     HLGADPVALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNRVFVISSADMVNWTDHGA
                     IPVAGANGANGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADSPIG
                     PWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGVSNPTQGQWANP
                     KTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPADKPPG
                     EIGYMTSSSPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQTVSSALF
                     GAGKGYRSPHINKLVHNADGSIQEVAANYAGVTQISNLNPYNRVEAETFAWNGRILTEK
                     STAPGGPVNNQHVTSIQNGDWIAVGNADFGAGGARSFKANVASTLGGKIEVRLDSADGK
                     LVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFNFDYWQFTQR"
     CDS             24525..25793
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEKQ
                     VIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAKSA
                     VKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYNKYAAYAQHLNDFVTFMKNNGVNL
                     YAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPILNDPQ
                     ALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDTNSADRWPEALDVS
                     QHIHNAMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVRIDATKN
                     PNANVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSNLQPGTNL
                     TVSGNHFWAHLPAQSVTTFVVNR"
     CDS             complement(26052..26315)
                     /locus_tag="ctg18_17"
                     /transl_table=11
                     /translation="MDEILKQYMVLYKKMSNMINGPDYPGKEKDIQHQKDQIEVYEKQL
                     QQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF"
     CDS             complement(26383..27882)
                     /locus_tag="ctg18_18"
                     /transl_table=11
                     /translation="MKRSISIFITCLLITLLTMGGMIASPASAAGTKTPVAKNGQLSIK
                     GTQLVNRDGKAVQLKGISSHGLQWYGEYVNKDSLKWLRDDWGITVFRAAMYTADGGYID
                     NPSVKNKVKEAVEAAKELGIYVIIDWHILNDGNPNQNKEKAKEFFKEMSSLYGNTPNVI
                     YEIANEPNGDVNWKRDIKPYAEEVISVIRKNDPDNIIIVGTGTWSQDVNDAADDQLKDA
                     NVMYALHFYAGTHGQFLRDKANYALSKGAPIFVTEWGTSDASGNGGVFLDQSREWLKYL
                     DSKTISWVNWNLSDKQESSSALKPGASKTGGWRLSDLSASGTFVRENILGTKDSTKDIP
                     ETPSKDKPTQENGISVQYRAGDGSMNSNQIRPQLQIKNNGNTTVDLKDVTARYWYKAKN
                     KGQNFDCDYAQIGCGNVTHKFVTLHKPKQGADTYLELGFKNGTLAPGASTGNIQLRLHN
                     DDWSNYAQSGDYSFFKSNTFKTTKKITLYDQGKLIWGTEPN"
ORIGIN
        1 gctcgaaggg aagctcaacc ctgaaaggat ggacagagct ttccaagagc tgatcaagcg
       61 ccacgagtcg cttcgaacct ccttcgaaca ggacgaagga ggcgatccgg tgcagcgcat
      121 ccatgacgag gtgccgttta cgttacagac tacagttctc ggcgcacgaa ccgaacagga
      181 ggccgcagcc gcatttatca aaccgtttga tctcagccaa gcgccgctgt tccgtgccca
      241 aatcgtaaag gtatcagatg agcggcacct attgctggtt gatatgcatc acatcatttc
      301 agacggtgtt tccgtcaaca ttctgattca agaattcggc gagctgtaca ataatcggaa
      361 gcttccggcg ctgcgcattc aatataaaga ttatgccgta tggcaagaag gattcaaaac
      421 aggagacgcg tacaaaatgc aggaggcgta ctggctgaag cagctcgagg gcgagctgcc
      481 tgtgctggat ctccccgctg atcatgcccg cccgccggtg cgaagcttcg cgggtgacaa
      541 ggtctcattt acgctggaac cagaggttgc atcaggcctt cacaagctgg cacgagaaaa
      601 cggaagcaca ctgtacatgg tgctccttgc ggcttacacc gcgttcttgt cacgcttaag
      661 cggacaggaa gatatcatcg tcggctcgcc aatcgccggc cggccgcaca aggatcttga
      721 gccgatactc ggcatgtttg tgaacacgct ggcgcttcgg acgcgcccgg agggcgggaa
      781 gccattcgta cagtatttgc aggaagtgcg tgagacagca ttggaagcct ttgagcacca
      841 gaattacccg ttcgaagagc ttgtcgataa gcttgaattg acacgagata tgagccggaa
      901 cccagtgttt gatgcgatgt tagttgttca aaataatgat tacgagccat tgcatcttca
      961 tgatttgcaa atgaagccgg cacaagtttc tcatctcgtt tctaaattcg atttgacact
     1021 acaggcatct gagggcgacg gaaacattca tttccttttt gaatattcaa ccgcattgtt
     1081 cgagaaaacc accattgaac gctgggcatc gcatttaaca aatgtactta gcatcatcgg
     1141 caaaaacccg aaggtgacac tcaaccatat cgacatcctg acccaagaag agcggcacca
     1201 gctgcttaat gagtttaaca ccgggcaagc gaatcaatac ggagttcaaa caatcagtca
     1261 attgtttgag cagcaagctg cacgaacacc aaaagcttct gcacttgtca gcggagacaa
     1321 aacactcact tatcaggagc ttgacgagtg gtccaatgga atcgcacgtg cattgcgcag
     1381 ccgaggtgtt aagccggaca caccagtagg catcatgatg catcgttcgt tcagtatgat
     1441 agcatccata cttggtgtgt ggaaagccgg aggctgttac gttcccattg atcctgaata
     1501 cccgaaagaa cggaaacgct atatcctcag cgacagcgga acgaaactgc tgatgacaat
     1561 aaatgaagcg gatctgggag tacttgctga ctttgaagga gagatcttga cgatagaaag
     1621 cgtagaggaa gacgacaaat cgccgctgcc gcaaatgtcg tctgcccatc atttggctta
     1681 tatcatttat acttcaggaa cgacgggccg tccaaaaggg gtaatggtcg agcataaagg
     1741 gattgctaac actcttcagt ggcggcgaaa cgcttatgca ttcaacgaga cagataccat
     1801 tctgcagctc ttttctttct catttgacgg ctttataact agtatgttta caccgctttt
     1861 gtcaggtgca aaagccgttt tgcttcatga agaggaagcg aaggatattc tggccattaa
     1921 gcatcagctg tctcgtcaac ggattacaca tatgattatt gtgcctgttt tatatcgagc
     1981 gcttttggac gtagtgcagc cggaagatgt aaagacgctt agagtcgtca cactggcggg
     2041 agaagcggct gaccgcgaat tgatcgcccg cagcttagct atatgtccgc ataccgaact
     2101 cgccaacgaa tatggaccga cagaaaacag cgtggcgact accgtcatga gacatatgga
     2161 aaagcaggca tacgtaagca tcggccagcc gattgacgga actcaagtgc tgattttaaa
     2221 tagcaatcat cagcttcagc caatcggtgt tgcgggagag ctttgtatag caggaacagg
     2281 gcttgcaaga gggtacgtta atcttccaga actgacagag agagcattca cgcagaatcc
     2341 atttaaaccc gaagcacgaa tgtaccgaac aggagacgcc gccagatgga tggccgacgg
     2401 tacactcgaa tatctcggaa gaatcgatga tcaagtcaaa atcagaggat accgtgtaga
     2461 aacgaaagaa attgaatcgg tcatccggtg tataaagggt gtaaaagacg ccgcagtagt
     2521 tgctcatgta acagcgtcag gacaaaccga attaagcgct tatgtggtga caaaaccagg
     2581 gttgagcaca aatgctgtac gctcagaatt acaaaacaag ctgccggtgt ttatgcaccc
     2641 tgcgtttatt gaaaaactgg actcacttcc attgtcacca aacggcaagc tggatcgcgg
     2701 agcacttcca aaacctgtat acaaccacga aggtgaacgt ccattcctcc cgccatccag
     2761 caaaatggaa caaatactgg cagatatatg gaaagaagta ctgggggcag aaaagatcgg
     2821 aacagctgat tcgttctttg aacttggcgg agattcaatc aaagcgttac aggtatctgc
     2881 gcggcttcac cggataggca agcaaatggc agtgaaagat ttgtttagcc atccgaccat
     2941 tcaagaattg gcagcttata tccgtgattc agatacaagt tccagccaag ctgcggttga
     3001 gggagacgta caatggtcgc ctgttcaaaa atggtttctt tctcaagata taaaagaaaa
     3061 acaccatttt aatcagtccg taatgctgca tcgaagcacc tctgtacaag aagacgcact
     3121 gcgaaaaacg ttaaaagcaa taacgtgtca tcatgatgcg ctgcgaatgg tgtttacaca
     3181 gaatgaacaa ggaaagtggg atcaatataa tcggccgctc agtcattcgg acgacgcgtt
     3241 gtacggcctt cagatgattg atttgtcagc tccggacggc actgatggaa atagaccgta
     3301 tgaacctctt atcaagcgcc atgtacttga tattcagcag aaaatggatt tgaagaatgg
     3361 tccgctgctg caagccggtc ttttccacac aattgacggt gatttcttat ttttatctgc
     3421 tcatcacctc gtcgttgacg gcatctcatg gcgggttctg cttgaagatt tggctttagg
     3481 gtatcgccaa gctgctggcg gggaggatat caaactgccg cctaaaacaa gctcgtttaa
     3541 agcgtatgcg aaaaagctct ctgactacgc tgaaagccag cagctaatga aacagctcaa
     3601 gtattggcgc gaagccgaag agtatcaaac agaggcattg ccttttgatc aaatcgatgg
     3661 aactagagca cacgagggac aacggtccac aatttcgttt accttaaacg ataaagagac
     3721 agcagcactc ttaaaagacg ccaacagcgc atataacact gatacgcagg acatgctgct
     3781 cgcttctgtc attcttgcgc tgcgccattg gaccaatcaa tccgccttca aactatcatt
     3841 agagggccac gggcgagagg atgtattaaa aggaatagat gtgagccgga cgattggatg
     3901 gtttaccgcc atttatccgt tattgattaa actgaacgca gacttgccag attcggaaga
     3961 aagcatggtt catgtgctaa aaacaacaaa agatacactg agacgtgtac ctgacaaagg
     4021 attcggctac ggtgtcatca aatatttgac tccgcctggc aaaaaagaca tcaatttcac
     4081 aggtgcacca gaaatcagct ttaattatct tggtcaattt gaaagcggcc gcacagctga
     4141 agtacctgag gaggacgcct tctcattctc tccgctgggt gccggaggtg atatcagcac
     4201 aacatggaac cgtgaacagt cgctggatat cagcgcaatc gctgcagaag gaaaattgac
     4261 tgtcaatatg acttatgaca atgcccgctt tcagcgcaaa accatcgaac agcttagcga
     4321 aacatgccgt caatttttat tacagctgat cgaacactgc cagaacaaaa gcgaaacaga
     4381 aaagacgatc agtgattttg atgatcaaga actgaccgag gacgccctgc aagagatcgc
     4441 tgatatgctc agttttcact aatgaatccg tgaagaaagg tgcagacact atgaatacca
     4501 ttaaaaaaat caagaacatt tatcctctga gtcatatgca ggaagggatg ctgtttcatt
     4561 ccttcctccg taaagaggag ggggcgtatg ttgagcagtc gctcttcacc attaaaggaa
     4621 gcctcagcta tgactggttc cagcgcagca ttcaagccat tatcgaccgc catgatattt
     4681 tcagaaccgt gtttttgccg cacgtcccgc atttgtcggg acctcggcaa gtcgtgatga
     4741 cagaacgtga attccatttg aacagcgaag acatttctca tctgccgaca aacgaccaga
     4801 atgagtatat tgaacgcttt aaagagaagg acaagcaaaa aggctttgat ctgcaaaaag
     4861 acatgctgat gcggatttct ctattcaaaa cagctaaaga tgagcatgtc tgtatctgga
     4921 gtcaccatca cattttaatg gacggatggt gcctaggtat cgttatgcag gaatttatgc
     4981 aaatttatca atcgattcat gcaggaaaac cgctttcatt agaccctgtc cgtccgtaca
     5041 gcacctatat ttcatggctg acaaaccgag acaaagaaaa agcagcggcc tactgggata
     5101 cctatttaaa aaactacagc gctccatcac ctctgcctcg tgtgtctgat aaagaaacaa
     5161 aagaaagtta tcaccgtgaa gatttgatat tttcattaaa taaaccactg acagacaagc
     5221 tgaaagagac tgccaaacaa cacggcgtca cgctcgctac ccttattcag gcagtctggg
     5281 gtgtgatgct gcagcaatat aaccgcacag acgacgttgt gtttggcgca gttgtatcag
     5341 gaagaccgtc agaaatccca ggcgtggagc aaatgatagg gttgtttatc aataccatac
     5401 cgattcgaat taaaacacac caagacgaaa cgtttcacga gctgctcata cgctgccaga
     5461 aagaaatgct ggaagctgag ccgtttacct gccagccttt atttgatatt caggcaaaca
     5521 ccgcattaaa acaggaactg attgatcaca ttatcgtctt tgaaaactat ccgttacagc
     5581 agaaaatcgc cgattccgct gatcaaaccg attcaccgct gcaaatcgat caagttcaag
     5641 tatccgagca atcaggatat aactttaatc ttgtcgttgc tcctggcgaa gagcttgtca
     5701 tcaagttcag ctataatgca ttcgtttacg atgctgcctg gatcagctgt atcaagaggc
     5761 aatttacgca agcgcttagc acagctgcac agcaccctca tatgccaatt gctgattttt
     5821 cttttcttga tgcaacagaa aaagagcaga ttgtcacaca gttcaacaat acaaaaacgg
     5881 agtatccaaa gaatcataca attatcgatt tatttcgcga acaagcagaa aagacgccag
     5941 accataccgc acttgtgtat ggcaatatgt ctatttcgta taaagagctt gataaacgct
     6001 ctaatgcgct cgccagagag ttaattcaaa agggatttcg gaaaaacgag acagccggaa
     6061 tattggctgc acattctccc gaattcatga tcagtgtgct tgccgtatta aaagcagggg
     6121 gagcatacct cccgcttgat gcggagcttc cgcctgaacg agtcagcttt atgcttgagg
     6181 aaacgcaggc aaaaatgctg attgttcaaa agggattgga gcaaaacgct gcgttctcag
     6241 gaacatgtat catttcagat gcgcagggat tgatggaaga gaacgatatc cctattaata
     6301 tcagctccag cccggatgat cttgcgtaca tcatgtatac ctcaggatca acaggccggc
     6361 cgaaaggggt catgatcacg aatcgcaatg tcgtgtccct tgtcagaaac agcaattaca
     6421 cgtctgcgtc cggtgatgac cggtttatta tgactggatc tatcagcttt gacgccgtca
     6481 cctttgaaat gttcggggca cttttaaatg gcgcaagcct tcatatcatt gataaatcga
     6541 caatgctgac acctgatcgg tttggagcgt atttgcttga aaatgacatt acagtgctat
     6601 ttttaacgac agctcttttt aatcagctgg cacaggtacg agctgacatg tttcgcggac
     6661 tccatacgtt atatgtcgga ggagaagcac tctctcctgc cctgatgaat gccgtcagac
     6721 acgcctgtcc agatctcgcg cttcataata tttacgggcc aacggaaaac acgacttttt
     6781 caaccttttt tgaaatgaag agagactatg cggggccgat tccgattgga aaaccaatca
     6841 gtaatagcac cgcttacatc ttagatacaa aaggacgtct tttgccaata ggcgttcccg
     6901 gcgagctttg tgttggcggt gatggagtcg ctaaaggcta tttgaacaga gtagatctga
     6961 caaatgctgt gttttctcct catcctttct tgcctggaga aagaatatac cgtactggtg
     7021 atttggcgcg ctggctgcct gatggaaact tagaatacat cagcagaatt gacaggcaaa
     7081 tgaaaatccg cggaaaacga attgagcctg ccgaaataga agcgcgcctg ttagaaatgg
     7141 aaggcgttca agaagcagca gtgacattga gagaaaaaga tggagaggcg cagctgtaca
     7201 ctcattacgt cggtgatcac aaaaaaacag atacggattt tcgcgccgat ttggcgcgtg
     7261 tgcttccaga ctatatgatc ccgcagcact gggtgcgtgt ggagcggatg ccgcttaccg
     7321 gaaacggaaa aatagaccgc agcgcgctgc ctattccaga aaataagcct gccaaacgac
     7381 agaacatcat attgccaaga aacttggttg aagaagaatt ggcgaacatt tggaagcaag
     7441 tcctcggtgt taacacaatc agtattgatg atgacttctt tgctattggc ggacattcac
     7501 taagagcact gcaagtcata catacactaa aacatcagca gaacattgac ataccgattg
     7561 atttcttgtt cgaacatccg acaatcgctc agcttgccga aaaactttat tctaaacagc
     7621 tgacagcagc aaatgaacag catgtgatca aactgaacca gcacggcgcg caaaatcttt
     7681 tctgcttccc gccgatatcg ggatttggca tttattttaa agaccttgct ttattgctga
     7741 atgagaaggc agccgtatac gggtttcact ttattgaaca agacacccgc attgaacaat
     7801 atgttaattg catgacggac atacagcctg agggcccata cgttttatta ggctactctg
     7861 caggcggaaa cctggctttt gaagtggcac aggctatgga gcgcaaagga ttagaagtca
     7921 gcgacttcat tatcgtggac gcttatctaa aagaacagcc tttgcctatc gataccggta
     7981 atgacgaatc tgcagcatat ctgcctgaag cagtcagaga aaaggtgatg aagaaaaaaa
     8041 gaaactatca ggaatattgg gcacaattgc tgaatgaagg ccacatcaaa gcaagcattc
     8101 atttcatcga agctggaatc caccccgaaa ccagcgggca tacaggctta acgaaatggg
     8161 aaggcgcctg cggaaactat agtgagtaca cgggttttgg cgctcataaa gacatgctgg
     8221 aaggaacata tgctgaaaag aatgccgaca tcatcctcga cattttagaa aagatcactt
     8281 caaatcaagt aatactgcac aaacgataaa gcggattagc ggacagaggc cattctctgt
     8341 ccgtctttct ttttgtatca agaatggata agggacactt gggaatgata acatcatcct
     8401 ttttcttgga ggcttctcaa tggaccgtct ttcttttcta acttttatca tgctgattct
     8461 agccagttac aggctgacac atttgattgt atttgacaaa atcacagaat ttatccgaaa
     8521 accttttatg aaaaagaaaa ggattgttga tcaaaacggg catgtagatg aaaaaagcgt
     8581 gccggcttct aactttggat acatgctcaa ttgctactgg tgtgccggtg tttggtgtgc
     8641 catcttgatc ggacttggct atcttttttt gcctcgtatt gcaataccgc tgatctttat
     8701 tttagccatt gccggagcac aagcgatcct tgaaacggct gtcggtgtcg gcgtaaaact
     8761 tattgatgtg ttaaaaagtc tgcaaaccat gatgaatgat aaaaagtcct aaaagcggtt
     8821 cacaacatgc tttaggactt ttttcgttta tttagtgaga tagacattct gttaatcacc
     8881 cttttatagc ccgggaatac cgtaatagcg aatagtgaaa gtgatgtaat gggggagaag
     8941 aaacagaatg aaggtttgcc aaaagtcgat tgtccgtttc cttgtcagct tgatcatcgg
     9001 aacgtttgtc atttccgttc cgtttatggc caatgcgcag tctgacaggg agctgagagc
     9061 cgtatggatt gcttccgtat taaatattga ttggccgtcc aaaaaagggt tatctgtgaa
     9121 agagcaaaaa caggagtata tcaaactgct ggacgatgtg caaaaaatgg gaatgaatgc
     9181 cgttatcgtt cagattaaac cgacggctga tgccttttat ccgtcagctt acgggccttg
     9241 gtcggaatac ttaaccggtg tccaagggaa ggaccccggc tatgatcctc ttgcatttat
     9301 gattgaagaa acccataaac gaaatttgga atttcacgcg tggtttaatc cttaccgtat
     9361 tacaatgaat catacagatc ttaataaatt gtctgaggat cacccggcaa gaaaacatcc
     9421 agattgggtt gccgcctatg gaaaccagct gtattatcat ccaggcattc cagaagcgag
     9481 agattttatc gtcaaaggca ttgaagaagt cgtaaaacat tatgatatcg atgctgttca
     9541 tatggatgat tatttttacc cttataaaat agcgggacag gaatttcctg atcaagcaca
     9601 gtacgaacaa tacggaaaag acgctttttc taatatcgat gactggcggc gggacaatgt
     9661 gaaccagctt gtcaaacaaa tcaaccaaac aattaaagct gcaaaaccgt atgtcaaatt
     9721 cggcatcagt ccctttggag tatggagaaa cgccgcagat gacccgaccg gatcgaatac
     9781 aaaagcaggc gtcagaaatt atgacgatct atatgcagac acaaggcatt ggatccaaga
     9841 aggcgacatc gattatattg ctccgcaaat ttattggagt atcggcttta acgcagcggc
     9901 ttacgacgtg ctggctgatt ggtggagcaa tgaagtcaaa aataggcctg ttcacttata
     9961 tattggccag gcagcatata aaatcaataa caattttgat ccgccttggt ccgatcctga
    10021 ggaatatgtg cggcaaatca ctttgaaccg ccagcttgaa ctggtgaaag gaagcatgca
    10081 tttcagcctc aaggacctca acaaaaatcc gcttggcatc aaagacagtc tcagcaccga
    10141 tctttacagc aagccggcac tggttccgca aatgccttgg cttgacaata ccgccccaaa
    10201 aaaaccgaag cttacgaaag tcaccgaaga caaaaacggc aatcttctgc agattaaaga
    10261 tcacccatca aatcaaaaaa cgaaagaaac agcctattat gcgatataca gagccgaagg
    10321 gaaaaagcag agaacattgc tggcaacgca aagaaaaaca catgagcagc aaaccttctt
    10381 agataacacg gcagatccca acaagaaata tacgtattat gtcacttcag cagaccggct
    10441 tcataacgaa agcaaagctt ccaaacgaac aacaaaataa gaaatgagaa ggacggcttt
    10501 ctaagtcgtc tttttttaaa aagtgatttt gggacaggaa acgatggtaa accgctgaat
    10561 tttttaaaaa acaaaggtga gattcacatg aatatggagg cggtgtttgg acatttacca
    10621 ttattggaat ctgagaaact agtactaaat aaaaataaaa tcgaagagaa acacgtacag
    10681 gacgtgtttt acgttttcat ttctagtctg gttaggtgcc acattatttt ttgtgctgtt
    10741 cggagatgct gtgttgactg atccggctga agaagccttt ttgccgaact ttcttctctt
    10801 gggagcgggc actgctcttg ttttatgcct tgtgttcttt ctctatcaaa aactcgatca
    10861 atcacagttc gcggtgatca agctaggtat atggggatca gcggtcggtt tattgatgga
    10921 tacgatttcc ctttggaatc ttcccctcat cttcccggct ttatcaaagg gccaagttat
    10981 tgcgtttacg atatggatgg tatgcgccta ctgcatgtat ttgctcatcc cgctgatatt
    11041 atcacataaa aaatgattca gttttaattt tcagactttt cttgtcaggg aatgattata
    11101 gaactcgcct aataggatgt tacaaagatg tgaaggagga aacgatgtga attttgagct
    11161 gacaaaagaa caacaaatgg tgcgtgaaat ggtaaaagat tttgcgaaaa aagaaattgc
    11221 tcctcacgct gaacatgtag atcaaacagg cgagttcccg atgcaaacat ttaaaaaaat
    11281 gggtgaactc ggtctgatgg gtattccatt tccagaagaa tacggcggat ctggcggtga
    11341 tacgatttca tatgccttag cggttgaaga agtcggcaaa gcctgcggca gtactggatt
    11401 aagctatgct gcagcggtct cgctaggcgc aagccctctt tactacttcg gaacagaaga
    11461 gcaaaaacag acgcatttga cgccgctggc ttcaggcaca gcactcggat cattcggcct
    11521 gacggagcca aatgccggct cagatgcagg aggcactcaa acaaaagcga tttcaaatgg
    11581 tgacgagtat gtaatcaacg gcgaaaagtg ctggatcact aatgcaagct acgcacgcac
    11641 agttattgta accgccgtaa caggcaaaaa caaagacgga aaaaacatca tctccgcatt
    11701 aatcgtgcca actgacacac caggacttac gattacgagc ccgtacgata aaatgggcgt
    11761 ccgcggttcg aatacagcgg aaatcttgct tgaagatgta agagtgcctg cggccaactt
    11821 acttggcgat ccaacaaaag ggtttaaaca gtttctatat acgctggatg gtggtcgaat
    11881 ctccatcgct gctcttgcag tcggcattgc ccaagcggcc cttgacgcat cattggcata
    11941 tgcgaaagag cgaaagcagt ttggacagcc gatttcttcc tttcaagcga ttcaatttaa
    12001 gcttgctgac atggcgatgg aaattgatct ggcacggcaa atggtgttaa aagccgcctg
    12061 gctgaaagat cataaccgcc cgttcaccaa agaagcggcg tacgccaagc tattcgcatc
    12121 tgaaatggcg acaagagctt gcaatcaagc cattcaaatc catggaggtt caggctatat
    12181 gaaagagtat ggggtggaac ggatgctgcg ggacgcaaaa ttaatggaaa tcggtgaagg
    12241 cacatctgaa attcagcgtc tcgtgatcgc cagacagctt ttaaaataaa aatgtaaacg
    12301 ctttcctatc attaagaaag gaggaacaat gaatggctga actcatccat tccacaatcg
    12361 gcaggctgct ggaacaaaca gctgatgcgt atcccgatcg agatgctgtt gtgtatccag
    12421 accgaaatat ccgctatacg tacgctcaat ttgacagtct gtgccgtcaa accgctaaag
    12481 gtctcatgcg gatggggatt ggaaaaggag accacgtcgc catatgggct tctaatatct
    12541 ctgaatggct tgccgtccag ttcgcaactg cgaagatcgg agccgtgctc gtgaccgtca
    12601 ataccaatta tcaagcacat gagcttgatt acttgttaaa gcaatcggat gccgcggcgc
    12661 ttattatcat ggattcatac aggggcactt cttatccaga catcgtgaac agtttaattc
    12721 cagaactgca agaagcaaag cccggccaac tgaaatctga acgctatccc tttttaaaaa
    12781 cgctgatcta tattggcaat aaacgattgt ctggcatgta tcattgggac gatacagaga
    12841 tattggcgaa aacagtgaca gatgctgagc ttgaagagag aatgaacagc ctggataaag
    12901 acaatgtgat taatatgcaa tacacatcag gaacgacagg gtttccaaaa ggcgtgatgc
    12961 tgacccattt caatgtcatc aataacgctg ctaatatcgc tgaatgtatg gctttaacct
    13021 ctcaagaccg catgtgcatc cctgttccgt tttttcactg ctttggatgc gtccttgggg
    13081 ttttggcatg tgtatccgtc ggggcagcca tgatacccgt gcaagaattt gatcccgtta
    13141 ccgtccttaa aacggtagaa aaagagaaat gcacagtgct ccatggtgtg cctaccatgt
    13201 ttatcgccga gctgcatcat ccggattttg atgcatatga tctatcgacg ctccgaacag
    13261 gaatcatggc cggctctccc tgtccaagtg aagtgatgaa agctgtgatt gaaaggatgg
    13321 gcatgaaaga cattacgatc gcctatggac aaaccgaagc ctcgccagtc attacacaaa
    13381 cgagagcaaa tgattccttc ataagaagag tcgaaacaac cggccgtgcc ctgccacata
    13441 ctgaggtgaa aattgtagaa cccgggacat gtcaagaagt tcaaagaggc atgcagggag
    13501 aactgtgcac ccgtggctat cacgtcatga aaggctatta taaagacaaa gatgcgacca
    13561 gaaaagcaat caatcatgac ggatggctgt ttaccggaga tcttgctgtc atggatgaag
    13621 acgggtactg ccgcatcacc ggaagattaa aagatatgct catcagaggc ggcgagaaca
    13681 tttatccgcg ggaaattgaa gaatttttat accagcatcc cgctgtttta gatgtacagg
    13741 tggttggtgt gcctgacgcc aaattcgggg aggaagctgc agcctggatt aaactgaaag
    13801 acggtaaaag cgtttcacct gatgagctta aagcctattg caaagggaaa atcgcccgcc
    13861 acaaaattcc gcgttatgtt atttttacgg atgactatcc gatgacggcc tcaggcaaaa
    13921 ttcaaaaata taaactgcga gaaaaaacga ttgaaatgtt caacttatca tcaagtcaat
    13981 gaggtgaaat catgtttaca aaagtactga tcgccaaccg cggtgaaatt gcaatgagaa
    14041 ttatccgaac atgcagccgt ctcggcatta aaacggtcgc tgtttattca gaagcagaca
    14101 aggacgcgcc ccatacaaaa gccgctacag aggcatattt gatcggggaa tcgagagtca
    14161 gtgaaagtta tttaaatata gagagaatca taaagacggc gaaaaaagca aaagccgacg
    14221 cgatccaccc gggatatgga ttgttatcag aaaacagccg gttcgctgaa cgctgcaagc
    14281 aagaaaacat cgtgtttatc ggaccttccc ctgatatcat cgcaaagatg ggcagcaaaa
    14341 ttgaagcgcg aaaagcaatg gaggctgcag gtgtccctgt ggtgccgggc gtttctgaat
    14401 ccctcggaga tatagaggca gcctgccgca ccgcaagtca aatcggctat cctgtcatgc
    14461 tgaaagcttc agcgggcgga ggcggcatcg gaatgcagcg tgttgaaaat gaagaagcat
    14521 taaaaaaagc gtacgaggga aacaaaaagc gcgcagcaga ttttttcggt gacgggtcta
    14581 tgtatataga aaaagttatt gaacatgcgc gccacatcga ggttcagctt ttggccgatc
    14641 aacacggcca tacagtacat ctgtttgaac gtgattgctc tgttcagagg cgccaccaaa
    14701 aagtcattga agaagcaccg tctccatttg tagacgatga actaagaatg aagatcggtc
    14761 aaacagcggt aaaagcagcg aaggcaatcg gctatacgaa cgcaggcacc atcgaattta
    14821 tagttgacca gaaacaaaat ttttatttcc tcgaaatgaa tacgagactg caagttgaac
    14881 accccgtgac tgaagaaata acaggcctgg acttagttga gcagcagctg cggattgctg
    14941 cgggccatac actcacattc tcccaaaaag acatccaacg gaacgggcat gcgatagagg
    15001 ttcgaatata cgcggaagat cccaagacct tcttcccgtc accaggtacg atcactgcgt
    15061 tttcacttcc tgaccaaaaa ggagtcagac acgaatgtgc ggtagcaaaa gacagcaccg
    15121 ttaccccttt ttatgacccg atgatcgcta agatgattgt caaaggccaa accagaacag
    15181 aagcaattga aaaactagag acagcgcttc gcgactatcg tgtagaggga atcaaaacaa
    15241 accttccgct cctcatacag gctgcggcaa caaaggcatt taaagaaggg gatgtcacga
    15301 ctgacttttt gaaacagcac ctataaagga ggcagttgtc atgacggtta gcatacaaat
    15361 ggcaggaaac ctgtggaaag tccacgtcaa agccggcgac caaatcgaaa agggccagga
    15421 ggtagccatt ttggaatcga tgaaaatgga aatcccgatc gttgcagata gaagcggaat
    15481 cgtaaaagaa gtcaaaaaaa aggaaggcga ctttgtaaat gaaggagacg tactgctcga
    15541 actgagcaat tccactcaat aatttggagg aagaccatgc catatcctaa aaaagtgaca
    15601 atcaaagaag tcggcccgcg tgatggctta caaaacgagc ccgtttggat cgcaacagag
    15661 gataaaataa cctggatcaa ccagctttcc cggacagggc tgtcgtatat tgaaatcaca
    15721 tccttcgttc acccgaaatg gattccggcg cttcgagatg ctatcgatgt agcaaaaggc
    15781 atcgaccgag aaaaaggggt aacgtacgcg gcacttgtcc cgaatcaaag aggactggag
    15841 aatgcacttg aaggaggcat taacgaggct tgcgttttta tgtccgccag cgagacgcac
    15901 aacagaaaaa acatcaataa atccacttct gaatccctcc atatactcaa acaagtaaac
    15961 aacgacgcac aaaaagcaaa cctcacaaca agagcctacc tctcgactgt tttcggctgt
    16021 ccgtacgaaa aagatgtccc cattgaacaa gtcattcgcc tttcagaagc tctatttgaa
    16081 tttgggattt ctgaactgtc gcttggagat acgattggag cagctaatcc cgcccaagtg
    16141 gaaactgtac ttgaagctct tttggcacga ttcccggcta atcaaattgc cctgcatttt
    16201 catgatacga gaggaaccgc tctggccaac atggtcacag cactccaaat gggcatcacg
    16261 gtgttcgacg gctcggcagg cgggcttggg ggatgcccat atgcgccagg ttcatcagga
    16321 aacgccgcaa ctgaggatat cgtgtacatg cttgaacaga tggatatcaa aacaaatgta
    16381 aagctagaaa aactgctatc tgcggccaaa tggattgaag aaaaaatggg caaaccgctg
    16441 ccgagcagaa atttacaggt gtttaaatca tcttgataaa agggaggacg catacaatgg
    16501 gagattctat tctttttact gttaaaaatg aacatatggc gttgatcacc ttaaacaggc
    16561 ctcaggcagc aaatgctctt tcagcggaaa tgcttagaaa cctgcaaatg attatccagg
    16621 aaattgaatt taactcaaac atccgttgcg tcatcctcac aggcaccggt gaaaaagcgt
    16681 tttgtgcagg ggcagacctg aaggaacgga taaaactgaa agaagatcag gttctggaaa
    16741 gtgtatctct cattcaaaga acggcggctt tacttgatgc cttgccgcag ccggtcatag
    16801 ctgcgataaa tggaagcgca ttaggcggcg gactagaatt ggcattggca tgcgaccttc
    16861 gaatcgcaac tgaagcagct gtgctgggac ttccggaaac agggttagct attatcccgg
    16921 gcgctggagg gacccaaagg ctgccccggc tgattggcag aggaaaagca aaagaattca
    16981 tttatacagg cagacgcgtg accgcacacg aagcaaaaga aatcggcctt gtagagcatg
    17041 tcacggctcc ttgtgacctt atgccaaaag cagaggaact ggccgcagcc atttctgcca
    17101 acggaccgat cgctgtccgt caggctaaat ttgcaatcaa taaaggattg gagacagatc
    17161 ttgctacagg ccttgcgatt gaacaaaaag cgtatgaaca aaccatcccg acaaaagaca
    17221 ggagagaagg gcttcaggcc tttcaagaaa aaagacgggc cgtatacaag ggaatataaa
    17281 agggaggcaa tgctgatgga ttatgaaaag gaacgaacag aacgggctga acggattcga
    17341 aaaggcggag cggaaaagta tcatcaaagc aatcgggaaa aaggcaagct ctttgtcaga
    17401 gagcggcttt cccttctctt tgacgatgac attgagctag aagacgcttt ttttgcggaa
    17461 tgtatgtcag acgggcttcc cgctgacgga gttgtaaccg ctatcggcaa aatcggcggc
    17521 caaaccgttt gcgtcatggc gaatgattca acagtgaaag cggggtcatg gggagcaaaa
    17581 acagttgaaa aaatcatcag aattcaagaa atcgccgaaa aattaaactg tccgctcatt
    17641 tatttagtcg attcggcagg cgcccgaatt accgaccaaa tcaatgtctt tccagggaga
    17701 cgcggtgcag gaagaatttt ttacaatcaa gtcaaattat cgggacgcat tccgcaaatc
    17761 tgtctgcttt tcggaccatc tgcggcagga ggcgcttata ttccggcctt ctgtgatatc
    17821 gtcgttatgg tagacggtaa cgcctccatg tatttaggtt cgccaaggat ggcggaaatg
    17881 gttattggag aaaaagtgtc tctcgaagaa atgggtggcg cccgtatgca ttgctcaatc
    17941 tccggctgcg gagatattct tgcagaaact gaagaagaag ccatacagct ggtgcgggct
    18001 tatttgtctt actttccggc aaattttcaa gaaaaagcgc ccattcatga gaaacgcccg
    18061 ccaaaacact tcgaaactcc gcttgccgac gtcattccgc aaaatcaaaa cgcacctttt
    18121 gatatgcatg agctcattga gcgggtcata gatgaagact cattttttga gatcaaagcc
    18181 ttatttgcac cggaattatt gacgggcctc gcacgaatcc acggacagcc tgtcggcatt
    18241 gttgcaaacc agccgaaggt aaaaggaggc gtcttattcc acgattcagc agacaaagcg
    18301 gctaagttta ttaccttatg tgacgctttt catatcccat tgctgttctt agccgatatc
    18361 cccggtttta tgattggcac aaaagtagaa caggctggga ttatcagaca cggagcgaaa
    18421 atgatttctg cgatgtcgga ggcaactgtt ccaaaactct ctgtcattgt ccgaaaagct
    18481 tacggggcgg ggttgtatgc aatggcaggg ccggcatttg aaccggattg ctgtctagcg
    18541 ctcccaaccg cccaaatcgc cgtcatgggc cctgaggccg ctgtaaacgc tgtctacgct
    18601 aaaaaaatcg ccgagctgcc agaagaagag agagccgcat ttatcagcag caaacgggag
    18661 gaatacaaag aggacatcaa tatctaccgt ctggcttcag aaatgatcat tgatgctgtt
    18721 atcccagcca attcgctgcg tgatgagctg gccaaacggc tcaaggcata catgacaaag
    18781 gaaatgacat ttaccaatcg aaagcatccg gtttatccgg tgtaaaagca agaacttagg
    18841 agcgcaaaaa aagcgctcct ttatatattt acaataacaa cattatgtca actaattacc
    18901 attgcataaa acgcttggtt ttttagaata gtaaataaag gctgccgcac ctctagcggc
    18961 aattgtcagt ttatcataaa aaggggccta cattatgtat catttatatt cacataacga
    19021 cttggacgga gtaggatgcg gaatcgtagc aaaattggcg ttcggaaaag acgtagagat
    19081 ccggtataac tctgtcaacg gcttaaacgc acaggtgcag tactttttag aaaaagcgaa
    19141 ggagagcaac agacaggacg cgttattcat caccgatctc gccgtcaatg aagaaaacga
    19201 agagagattg aatgagtatg ttcatgcagg gggcaaagtg aagctcattg accatcataa
    19261 aacagccctt catttgaatg agcatgaatg gggatttgtc caggtggaat acgatgatgg
    19321 aaggctcaca tccgcgacat cgcttttata tggctatctc attgaaaatg gcttcatgaa
    19381 accgacaaac gccttagatc aattcacaga gctcgtccgc caatacgata catgggagtg
    19441 ggagcggtac gatcaaaaac aggcgaagcg gcttaatgat cttttctttt tgctgtcaat
    19501 cgatgaattt gaagcaaaaa tgatccagcg cctttccacg catgacgaat ttttcttcga
    19561 tgattttgaa gaaaaactgc ttgatttaga agacgaaaaa atcgagcgct acctccgcag
    19621 aaagaaaagg gaaatggtac aaacctttgt tcacgaacac tgtgtaggca tcgttcacgc
    19681 tgaatcgtac cattcagagc tggggaacag gctagggaaa gataacccgc acctcgatta
    19741 cattgcgatt ttgagcatgg ggtcaaaacg agtcagtctc cgcaccattc atgattacat
    19801 cgatgtgtca gaaatcgccg gccgatatgg cggcggaggg catgcaaaag cgtccggctg
    19861 ttcaataacc gatgaagtat acgagttgtt tgtagctgaa gctttccgta ttgatcctgt
    19921 acggccggat gccttccgta acatctataa tctaaaggga tctgcgaatg gatcattata
    19981 tgaaaatcgc gcacaaatga gattttttct tttcccttta gacaacgaat ggaatattca
    20041 aattaacgga gaaacccaag acgaaacatt cgcagcgttt gaagaggcag aatggtttat
    20101 taagagaaat tatgccgcat cgctcgtgcg ggatgaagtg tttgtcgcat ttttagcgga
    20161 gaatctgaag ctggcaaatc aacatcgcaa gtaaaaaaat atgcataggg gagcgtcagt
    20221 cacccctatg catatccgct agctatcgtt taaatatggc tgtacgtttc ttaatcacaa
    20281 aataaagggc tatcacgaca acagccaata tcataatcgg tgttgtataa gtgcctgcta
    20341 tattctcaac atcatcccac tggcttccta gctgtatgcc taaataaaca aacaggatag
    20401 accatggaat gatagcaagc acagtcagta ccacaaattt gagaaaaggc attctggcaa
    20461 tacctgccgg aatggatatg gcatgtctga caaccggtat aaaacgagcc gagaagacaa
    20521 ctccggcgcc gtatttctga aaccagtttt ccgacatatc gatatgatgc tttttaatca
    20581 ataaatactt cccgtatttg tccagaaatg gcctgccgcc atagcgaccg atccagtaaa
    20641 taaagatctg ggcaatggtg cccccgataa cacccgcaat aattgcgcca ataaatccaa
    20701 tcgtgccctc cgataccata tagccgccat aagctaatac aatctcactc ggaatgattt
    20761 caatcattaa cccaatcgca atacccgcat atcccatgtt cgtcagccat gttaaaattt
    20821 cgcttatcaa actgcccaca ttcttcacaa cctgtcctaa tctttttcac tattatatga
    20881 ctgattgacg agcaagatgg ttacaatttt tttaccgcag catttctttc gtttcccgtt
    20941 tgatcacatc ttctaaatag gccaaaagct gagatctcat ttcgggacgc attaagccga
    21001 tttcggtgct cgctttaaaa cagcccagct tatcgccaat gtcatatcga tttccttcca
    21061 gcagccgggc atggatcggc tccttacggc aaacctcacg aagcgcatct gtcagctgaa
    21121 tttcgttgcc cgcgcctctg ccaattgtct tcaaaacgga gaagatcgaa gaattcagca
    21181 cataacgtcc cattactgcg atttccgaag gtgcttcttc aggagaaggc ttttccacta
    21241 aatcgttcac ttcatataca tgcccttgag accctgatgt atttataata ccatatttgc
    21301 tgacatcctc agggagaact gactgtacac cgacaacctc tgtgccataa acgtcatata
    21361 catccattaa ttgccgaaga gccggtgttt cagacaccat aatatcatca cctaagagaa
    21421 cagcaaaagg ctcatctccg ataaaatgct ccgcacacag caccgcatgg cctaatccga
    21481 gcggttcttt ctggcggatg taatgaatgt tggccaaatc ggcaatctgc tgcatttcct
    21541 taagtgtctc cgtcttgcct ttttcccgga gattgaattc caattccgcc gaccgatcaa
    21601 aatgatcttc aatcgagcgt ttgtttctcc ctgtaataat cagtatatct tcaattcctg
    21661 actctgcggc ctcttctaca atatattgga ttgctggttt gtcgacgatt ggaagcattt
    21721 ctttaggctg cgcctttgtc gccggcagaa atctcgttcc taaacccgct gcgggtataa
    21781 ccgcttttct cacttttttt ctcattcatc ttcactcctg atcctgtatg tttttcagcg
    21841 aatctccaaa tacccagatt cggtttccga taaaattcat catcattccg ccgatagtgg
    21901 cggcgagctt actcaccaaa agcgagcagc cgcaattttg aaacaaataa agcagcaaaa
    21961 aggtgatccc tgacgcggca atattaatca tgagaaaacg cacgatctct ttcccgtcag
    22021 ccttacgttt cacacaaaac gtccaattcc ggttccacac atagctgttg acgatacctg
    22081 cagtatagga gcagatctgc gccggcagat aagagacatg acaagcggta agaagaaaga
    22141 agacaccaaa atctatcagc gtattgccga cgcctacggt gcaaaaacgg cctaatgtct
    22201 ttattttttc tttcagcgta acgaacctcc cttcataaaa gatgcgagtg gcagtcatat
    22261 ttgttgatat ggattactat agcggacagt gttgaataaa caattaataa aatatgaaca
    22321 aaacatgaaa aagcgggtat accgctcaat agtcttatac tcttgaaaaa aacagccgca
    22381 ttgaacggct gttttttgtg tctgaaaaca tacaaatata aacggagtgt tagccccatc
    22441 ttatcaatga ataaatgtat ccagttcctt tgtagaatcg aacactaact cctccaaaag
    22501 tttctataca caattttttt aatgatgtag gatgttagat aaagggatat cttggataat
    22561 gatgtaatct ccgttcaatg tgattagtgg gaggccatga acaatcctgt ctttttattt
    22621 tctggacaat ggtcgctagg aatggggaag tttttttgaa caattttgaa ggagtggtgc
    22681 gatctcctcg aagaaaagag agaatggaga cacatgaaga tgagctttca gaacaactgg
    22741 gaacattgct aaacagcttc cggctacttt atgcgtgcaa tcttcgtgac ctgttgttat
    22801 caaattccaa aagaaaatcc cccattttaa ggaaaaagga ggatgtgaag tgatgaggaa
    22861 aaagtgtagc gtatgtttat ggattctagt tttattattg agctgcttat ctgggaagtc
    22921 tgcgtatgct gccactagta ctacaattgc aaaacatata gggaattcaa atccgcttat
    22981 cgaccatcat ttgggagcgg atccggttgc gctgacctat aacggaagag tctacatcta
    23041 tatgtcaagt gatgactatg aatataatag caacggaaca attaaagata attcatttgc
    23101 caatttgaat agagtattcg tcatatcttc agcggatatg gtgaactgga cagaccacgg
    23161 agccattccg gtagcaggtg ccaatggagc taatggaggc cgtggaattg caaaatgggc
    23221 aggtgcgtca tgggcaccgt caatcgcagt taaaaaaatt aatggcaagg ataaattctt
    23281 cctttatttc gcaaacagcg gcggaggtat cggggttctc accgcagaca gcccgattgg
    23341 tccatggacc gacccaatcg gaaaaccgct cgtaacgcca agtacgccag gaatgtctgg
    23401 tgttgtatgg ctttttgatc cggcagtatt tgtagatgac gacggaaccg gttacctgta
    23461 tgccggcgga ggcgttcctg gcgtttcaaa tccaacgcag ggacaatggg ccaatcctaa
    23521 aacggctaga gtcataaaat tggggcctga tatgacgagt gttgttggaa gtgcatctac
    23581 aattgatgcg cctttcatgt ttgaagattc gggattgcac aagtataacg gaacatatta
    23641 ttactcctat tgcatcaatt tcggcggcac gcacccggcc gataaacccc cgggtgagat
    23701 cggctacatg accagttcaa gtcccatggg tccctttaca tatagagggc acttcctgaa
    23761 aaatccgggt gcatttttcg gaggtggcgg aaacaaccat catgctgttt tcaattttaa
    23821 aaacgagtgg tatgtggtgt accatgcgca aactgtcagt tccgctctgt tcggggccgg
    23881 caaaggatac cgctctcccc atattaataa gctggtgcat aatgcagatg gatctattca
    23941 agaggtagcg gcaaattatg caggtgtaac acaaatttcc aatttaaacc catataaccg
    24001 ggtagaagct gaaacgtttg cttggaatgg acgcattttg acagagaagt ccacagcacc
    24061 cggcgggcca gtaaataatc agcatgtaac aagcattcaa aatggagact ggattgctgt
    24121 aggaaatgca gacttcggag cgggcggtgc caggtcattt aaagcaaatg tagcatccac
    24181 tttaggcggg aaaatagaag tgcgcctcga cagtgcagac ggtaagcttg ttggaactct
    24241 gaatgtgcct tcaacaggcg gagcgcaaac gtggagggaa atagaaactg cggtaagcgg
    24301 ggcaaccggt gtgcacaaag tattctttgt atttaccgga acaggtacag gaaacttgtt
    24361 taattttgat tactggcagt ttacgcaaag atagtactcg taatgggacc gcttaaaaac
    24421 gaggcgggtg aagtacgggc cagcaccgga acagcccgcc attatggata tgccatgcag
    24481 attttttaat accgtaaaag acacatgacg aaggagagga ataaatgatt ccacgcataa
    24541 aaaaaacaat ttgtgtacta ttagtatgtt tcactatgct gtcagtcatg ttagggccag
    24601 gcgctactga agttttggca gcaagtgatg taacagttaa tgtatctgca gagaaacaag
    24661 tgattcgcgg ttttggaggg atgaatcatc cggcttgggc tggggatctt acagcagctc
    24721 aaagagaaac tgcttttggc aatggacaga accagttagg attttcaatc ttaagaattc
    24781 atgtagatga aaatcgaaat aattggtata aagaggtgga gactgcaaag agtgcggtca
    24841 aacacggagc aatcgttttt gcttctcctt ggaatcctcc aagtgatatg gttgagacct
    24901 ttaatcggaa tggtgacaca tcggctaaac ggctgaaata caacaagtac gcagcatacg
    24961 cgcagcatct taacgatttt gttaccttca tgaagaataa tggtgtgaat ctttacgcga
    25021 tttcggtcca aaacgagcct gattacgctc acgagtggac gtggtggacg ccgcaagaaa
    25081 tacttcgctt tatgagagaa aacgccggct cgatcaatgc ccgcgtcatt gcgcctgagt
    25141 catttcaata cttgaagaat ttgtcggacc cgatcttgaa cgatccgcag gctcttgcca
    25201 atatggatat tctcggaact cacctgtacg gcacccaggt cagccaattc ccttatcctc
    25261 ttttcaaaca aaaaggagcg gggaaggacc tttggatgac ggaagtatac tatccaaaca
    25321 gtgataccaa ctcggcggat cgatggcctg aggcattgga tgtttcacag catattcaca
    25381 atgcgatggt agagggggac tttcaagctt atgtatggtg gtacatccga agatcatatg
    25441 gacctatgaa agaagatggt acgatcagca aacgcggcta caatatggct catttctcaa
    25501 agtttgtgcg tcccggctat gtaaggattg atgcaacgaa aaaccctaat gcgaacgttt
    25561 acgtgtcagc ctataaaggt gacaacaagg tcgttattgt tgccatcaat aaaagcaaca
    25621 caggagtcaa ccaaaacttt gttttgcaga atggatctgc ttcaaacgta tctagatgga
    25681 tcacgagcag cagcagcaat ctacaacctg gaacgaatct cactgtatca ggcaatcatt
    25741 tttgggctca tcttccagct caaagcgtga caacatttgt tgtaaatcgt taagagcaca
    25801 aagacacaca taaataatag agtgtctgaa ttggcgattt tccgattggg aaatcgcttt
    25861 tttattttgt tgctgaatta caggaagaag aaaggatgta cataaaaaca gcaaagcttt
    25921 attcttcatc ttttctagtt tacataatat atattctagg aagtaaacaa aataaataaa
    25981 tttctgtctc aatatcaaag tatacttaag ttagtgagac agaaattgaa attttactgc
    26041 tgaatgacaa atcaaaaaaa tggtgttgtc aatccataat aaacggcttc taaatcttcc
    26101 agcgtcatat cgccatatgc gcatttgata acagaatcag caaacacatc atagtcataa
    26161 tctgtagaaa atccttgctg cagctgtttt tcgtaaactt cgatctgatc tttttgatgc
    26221 tggatgtctt tttccttacc tggatagtcg ggaccattta tcatattact cattttttta
    26281 tacagcacca tatactgttt cagtatttca tccacaacgc aaacctccta ttagatgata
    26341 aaaacggaca tcgttactga tgtccgccaa aaaaaagctt aactaatttg gttctgttcc
    26401 ccaaatcagt tttccttgat catataatgt gatttttttc gttgttttaa acgtatttga
    26461 tttgaaaaag gaataatcgc cgctttgtgc ataattgctc cagtcatcat tgtgaagacg
    26521 gagctgaata ttccctgtgc ttgctcccgg tgccaacgtt ccgtttttaa atccaagttc
    26581 cagataggta tctgcacctt gctttggttt atgcaacgtc acaaacttgt gtgtcacatt
    26641 gccgcatcca atctgcgcgt agtcacagtc aaagttttgg cctttgtttt tcgctttata
    26701 ccagtaacgg gcagtgacat cttttaaatc aaccgtggta ttgccgttat tttttatttg
    26761 aagctgcgga cggatttggt tgctgttcat actcccatcc cctgctctgt actgtacaga
    26821 aataccattt tcctgtgtgg gtttatcttt tgatggcgtt tcaggaatgt ccttcgtcga
    26881 atctttggtg ccgagaatgt tttctctaac gaatgttcct gaagcagata aatctgacaa
    26941 ccgccagccg cctgttttag atgcccccgg ctttaaagct gaggatgatt cctgcttatc
    27001 agaaagattc cagttcaccc agctaatggt cttgctgtcg agatatttca gccattccct
    27061 cgattgatca aggaatacac cgccattgcc agacgcgtcg cttgttcccc actctgtcac
    27121 aaaaataggt gctcctttgc tgagtgcata gtttgcttta tcccgtaaaa attggccgtg
    27181 tgtgccggca taaaaatgaa gtgcgtacat aacgtttgca tcttttagct ggtcatcggc
    27241 agcatcattc acatcctggc tccatgtacc ggttccgaca atgatgatgt tgtctggatc
    27301 atttttgcgg ataactgaaa tcacttcttc cgcatatggt ttaatatcac gcttccagtt
    27361 cacatcaccg tttggttcgt ttgcaatttc ataaatgacg tttggcgtgt ttccgtaaag
    27421 gcttgacatt tccttgaaga attcttttgc cttctcttta ttttggtttg gattaccgtc
    27481 atttaagata tgccagtcaa tgatgacata tatcccaagc tcttttgccg cttcaaccgc
    27541 ttcttttact ttatttttca cggacgggtt gtcaatataa ccgccatctg ccgtatacat
    27601 cgctgcacgg aaaacggtga taccccaatc atctctcagc cattttaagc tgtctttatt
    27661 gacatattct ccataccatt gcaatccgtg tgaactgatc cccttcagct gtaccgcttt
    27721 accgtctcgg ttaacgagct gtgtaccttt tatgctaagc tggccattct tggctactgg
    27781 cgtttttgtc cctgctgctg atgccggcga agctatcatg ccgcccattg tcaataacgt
    27841 aatcaataaa cacgtaataa aaatagagat tgaccgtttc atatctgatc ttttcctcct
    27901 tcgcatcatt ttggctctac acttcttatg agcacgaact cattgtaaaa atctttctca
    27961 tgattgtcta tcaacctaat ttcttgtttt ggggaggttt aaaagcctgt caatttgctc
    28021 tacctccaat gaataagaca cacatgacac atatagaaca aagaaaactg gactgaattg
    28081 ggactttaca cgtcattttt cattcgagtc gaaaaattaa atttatttcc aataatgaaa
    28141 aagctgcatt caactattga atgcagcttt gttttatatt tatattatgc ttcttgtttc
    28201 tcatcttccc atgtttcagc gtttttcagc cctgggatgt ttttcgcttt aaacacagga
    28261 tcaagtcctt gcttacgctg tttcgcgtaa tctttataca ctttgtaag
//
