LOCUS       gnlProkkaGKAFKPJL_24   21612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GKAFKPJL_24.
ACCESSION   gnlProkkaGKAFKPJL_24
VERSION     gnlProkkaGKAFKPJL_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:33:48
            Original ID  :: gnl|Prokka|GKAFKPJL_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 8619
            Orig. end    :: 30231
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11612]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(421..540)
                     /locus_tag="ctg24_9"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
     CDS             complement(524..1669)
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             1899..3254
                     /locus_tag="ctg24_11"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLISFIPNHEFAYVFTGTVVYVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQEF
                     FFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSPNGAGVIGN
                     VPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     CDS             3293..4669
                     /locus_tag="ctg24_12"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDFPEGFKVDTAEAS
                     AAVTWSTDNLSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGDGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDVNTGQLVESIIDTFEFPSLITTPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(4675..5376)
                     /locus_tag="ctg24_13"
                     /transl_table=11
                     /translation="MKQSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPAFSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(5373..6653)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_14"
                     /sec_met_domain="Peptidase_M16 (E-value: 1.3e-14, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLAIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     CDS             complement(6658..7842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_15"
                     /sec_met_domain="Peptidase_M16_C (E-value: 3e-06, bitscore:
                     21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKT
                     FADLSFPSSLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIKAIHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             complement(7808..9118)
                     /locus_tag="ctg24_16"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVVYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             complement(9111..9830)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.5; E-value:
                     1.1e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_17"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYMS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             complement(9827..9988)
                     /locus_tag="ctg24_18"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             complement(10001..11347)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_19"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1080.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.7e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.8e-23, bitscore: 76.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.2e-11, bitscore:
                     35.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.4e-10, bitscore: 33.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKAYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYVSIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(11481..11612)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_20"
                     /sec_met_domain="Subtilosin_A (E-value: 4.8e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(11583..11612)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg24_20_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11481..11582)
                     /prepeptide="core"
                     /locus_tag="ctg24_20_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[11582:11612](-)"
     CDS             11925..12353
                     /locus_tag="ctg24_21"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             12350..14020
                     /locus_tag="ctg24_22"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             14156..15343
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 105.7; E-value: 3.7e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_23"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     CDS             15442..16158
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 124.1;
                     E-value: 8.2e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_24"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     CDS             complement(16190..16909)
                     /locus_tag="ctg24_25"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     CDS             17053..17529
                     /locus_tag="ctg24_26"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             17723..21409
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 80; E-value: 1.9e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_27"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYSYVRGVLINLWREALQEHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPCLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNG
                     EETYITTVFDLILANYGVNRGIGKRSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKQRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
ORIGIN
        1 tcataagcca aaccaaaggg gcaaactcct ccaatttcat ggcctgtctg ctccagtacc
       61 tcattaggag agagcattct tgctttaaag ccaaatgttt gcctgaacgt tttgttgtcg
      121 atcttggcat cgccggctgc cacaatcaga atcgcctgat atccttcccc tctgaaggac
      181 agggacttgg cgattctagc cgggtttacg ccgatcgtct cagctgcctg ttcaactgtc
      241 gcactcgacg tttcgaactc cgtcacatca ttttctcgat tccactgtgt aaagtgggtt
      301 ctcacacttt acagagacat gctgcatttc cactctcttc aagattattg aaaaaaaatc
      361 atagcatgaa ttgggagatt gggtaaagag gggacaaaaa aaaccgccga tggacggcgg
      421 ttaaatcatt cctcgttgtg caacttcaat ttggtgtgta ggtgcatttg caatagttgt
      481 tgccacgaac acagtgctta gagccagaca agagagtaat agtttagact tcaatttcat
      541 acaaactcac tcctccttga ataagttgcc ttacttgttc caccttcaaa aaataagcag
      601 aagctttttg aaaattttta cgttcatgat aatattttgc cacatcaata gcgaaatctt
      661 caagatcagc atacaacatt ttactttcga gaaaatcaaa aaatccttga attgcttctt
      721 catccgggcc tgataagtat aaagatttca aaaattcaaa ctctgataaa tatattacat
      781 ctccggcctt ttgtgaataa gccattccct tactatgata ttcatgagct ttatccattt
      841 ttcctaattt ataatggatc tgtgtaatta aaaaatacgc ttgaggtaag gaaggaagaa
      901 tatttgattc ttcaaaaaca gctattgctc ttttgaaata tgttatggca tcctcatatt
      961 ggctttggct gtttttacaa agcccgatat tgtacaaagt tcttcccatt aattggggct
     1021 gcttttcagc ttctgccata gaataagctt tttgaaaatg tgagacggca tcctcatact
     1081 gttttaaatc taaaaaattg gtggcaaata aagaatgaca ctgcagcaat cttatattat
     1141 aagcttcatt ttctttgtat atttcatatg cttgccgtgc atagtccatt gaaaaatacg
     1201 tttgtttcat atagtaataa gattcagaca tcttaaagaa aaactcagct ttctctatcc
     1261 gatccttaac gaatatcagc ttgctttcgg cctttttgaa aaatttaata gccgacagat
     1321 attcccgctg atccagctca tacatgcctc tgaagaaatt aaaatagtac tcaagcagac
     1381 cagttaaacg agcctgtttt ttatcaatct caagcagcag atcagacagt ctcggctgtt
     1441 cctcaatcct cattttttct aacggttcaa ggtactcaag cattaggttg tgccgaaact
     1501 ccatcagtga atagtacaaa tgaaggtctt gatcttcttc catttgatcc agctcttgct
     1561 tgatttctcg tcgcaaatat tctgcatcgg gtatgctgaa tcggcgtatg tacatatacc
     1621 attcgttaat cttttctccg atggaagaag aagatatgac acctgtcacg tttgcaaatc
     1681 cctcccttca taattctata tatgtcatat tttatcatca acattcttgt gagaagcgca
     1741 aaaaaaccgc aattttttct ttcgttacac cgcatgtttg gagatatatt ttcaaaaaga
     1801 agcgtttacc ctcagcaatt tgtacaagca aacacgttaa ccttccatat tctgttatat
     1861 ctgcgtgagc agtgtatgtc tgaaaaggaa gtgaaggaat gagaaaaaac aagctttcct
     1921 ttaaagaaaa agcaggagca gaacaagaag aatgcttatg tttttgtgag ggagaagcaa
     1981 gccgagaagc catgtttcaa gcgccgattg aattacctga agggtttgtc gttgatccgg
     2041 ctgaagctgt tgcaaacgtg acgtggaatg cagacagcct ttcttgtgtc agtgaccgtt
     2101 gcttaattca aacggggcca gagcctgatg aggtcggtgt tcaatttgca gtgcgcctgc
     2161 agggaaccgt tacgctactc gtcagtgtct cacctgtgcg aaatcaatat ggacaagggg
     2221 acggggctgt ttccgtcatt cacaatgcag aaatcgatca agtcgtctat tattccgatg
     2281 aaccggatga ttgcccggat atcagtgaca tcacgattga gaaccttgtt gttgttccgc
     2341 cgttttacgg cagtccttta tcggtgacgg ggacgattgt gcttgtaccg gagccggaac
     2401 ccgtctacgc gtttacagcg aatccaaatg atcaatcagt ttctgtgatt gatacaaaca
     2461 cccatactgt tgtgacaacg attgctcttc cgtacaatcc ggcaggtatt gaaattacgc
     2521 cagataaaag cgctgtgttt gtcttacatc ccaacaataa tgtgatttct gtcatcgatt
     2581 atgacacatt aacagtgaca gcaactatat tgctggatca gccgcctcga ttgattagtt
     2641 ttatccctaa tcatgagttt gcttatgttt tcaccggtac tgtggtttat gtgattggaa
     2701 ttgatacgtt aactgtggat aggtcgattc ctgtggaagg atatgatgtt gcaatcgatc
     2761 ccaatgggtt attcgcctat gttctgaatt ttggaatagt gcaaaaagtg gacctaacta
     2821 ccggtgaagt cacaggaaca attgaacgag agcttatcgt atcaaccata gaaacaaatt
     2881 ggccggagcg gtatgcctat gtattagaac aagaattctt ttttaattat ttgacggtta
     2941 ttgatttaaa tacgtttacc atcagcagca cccaagagct ggagtatgaa ggggaatatc
     3001 gaatgtttac gagtggagca gaggtgtatt tatatgacgg cttcactggc aatttatatt
     3061 ctgtcagtcc aaatggagca ggcgttatag gaaatgttcc gcaatcagca acagactatg
     3121 cgtttacccc gaatggcgat tttctgtatg caactcgttt tatagagcag agcatcattg
     3181 tttacaacac agatgattat tctgaggaaa ctgtgatatc tcttggggtt tcaccgggtg
     3241 ccattacgat ttaaccgctg catgttgtgc atttctaaaa ggacgtgaaa tcatgaaaaa
     3301 gaatgatctt tctgctttac aggaaaattg tttctgtttt tgtgatgagg aaattagccg
     3361 ggaagcgccg tttcaagtgc cgatagattt ccctgagggc ttcaaggttg atacggccga
     3421 agcgtcagcg gctgttacat ggagtacaga caatttgtcc tgtatcagtg agccttgctt
     3481 aatccagact gggccggaac cagaagatat cggtgttcga tatgctgtga gagtacaagg
     3541 gaccattacg cttcttgtca gtgtgtcgcc tgtacgaaat caatatggac aaggagacgg
     3601 ggctgtttct gtgattcata ctgaagagat tgatcaagtt gtttattatg cagcacagtc
     3661 tggccgctgt cctgatttca gtcaaataac agtggaagat ctgctcattg taccgccttt
     3721 ctacggcagt ccgcttacgg tggccgggac acttgtttta ccgccatcac cagaccctca
     3781 atcgtatgtg tttactgcca atactggaga cagcacggtt tcggttattg atgcagattt
     3841 aaacactgtt gtaaaaacaa tccctttttc tgacgtgcca actaatctag gcgttacttt
     3901 cgataaagca ttcacgtatg tcctccatgg aaataccaac cttgtctcag tgattgataa
     3961 taaaacatta accatcataa ataccattac tgttggagga gggccgagaa aaatcgaatt
     4021 tgatccaaca gatgagttcg catacgtgat ggccgccgga tctatatatg tgattaacac
     4081 ggcctctcaa tcggtcattg atgtcattcc gatacccggc gctttagact ttgctcttga
     4141 tccgaatgga cagtatgtct ataccgctaa tggaagcagt tggtcggttg ataaatatga
     4201 tgtaaatact gggcagttgg tagaaagtat catagataca tttgaatttc ccagtttaat
     4261 tacaactcct tacgctggaa attttgcgta cgtattgaat ggtgagctgt ggccgaaagg
     4321 tgtaacggag attagtttgt caccattaag caggggaggg gacttcagcc gtttatttga
     4381 aacgctgagg acgattgtat tttctctcga tagtactaga gcttattttc tagagccata
     4441 tagtgaaccg tttctcatta ataacttata cgtagttaat acggccagac agaggatcat
     4501 tgcaaacgtg tctctccccg gcgcctttga cctcgccgta acgccggaca aacagtatat
     4561 ttatgcggca cagcccaacg acaatgctgt gaccgtgtac cgcacaagtg attatacagc
     4621 cgtgacggtg attccggttg gcgcgggtcc gtctgcgatt gcgatgtagc tattttatag
     4681 atcaagagaa gcggtgctgc gataagagaa tcgtttataa ataaatgatc cgatttgctg
     4741 aatggcagcc aggataatca gaaacagcag ttcacttata gagaaactga gcatccacca
     4801 aatcccggct gctgccagtg ctcccgcaaa cacttttctg aacaggctgc cgtgccggaa
     4861 aagctgccgc aaatacgttc gcatgcaaaa caataaatac aggatcagta gcatcgcaag
     4921 tcccattgaa aaggcagggg gcgtatgaag gcggaaaggg acggctttaa cgatttcgaa
     4981 catgcagccg aatatgatga cttggcacaa cacggcagcc atcacgtatg tttggcggac
     5041 gtttttatag ctgtcacgca gcgatttgac gtcttctgca tatcggctgc acaagttgtg
     5101 ttgctgaaag tcacagcagc tttgatgaga ctgtgtgagt ttctgaaaag ctgctgtcat
     5161 gtttttcacg gattgggtga catagtgaag atagagaaaa gcaggcagca tcaggagggc
     5221 agcggtacaa gccagcagtc cgagccgcac agcatcattg ttgatcatct gtacatattg
     5281 ggcggcggct tcggcaacgg cctgaaccca gccgaaggaa taagccgcca tacctataag
     5341 cagcaataaa agggtaaaga cagtgctttg tttcattgtc tgatcgcctc tttctgagaa
     5401 acgtgaatga tcgctttgtt agaagatgcc attgcatcaa tgagagacaa gaaaacctgc
     5461 gcatccatat cttgaatgat gtggtacatg tcaagaaacg agcaatcgca cctgtcacac
     5521 tcggctgccc actcgaagca tttacgcaca taatcgctgt cataaatgat cgcgtctgtc
     5581 aaagagtcct tgccgtattg aagccaggcg gcaacctgtt ctttcttctg tgtgacatag
     5641 tatgaagcca catcgatata agctgaagaa tgggtccctt gactgtgaag gatcaagaaa
     5701 ccgccatcct catagatata agtctcggct gacaaacgat cgatttccag acggtacgtt
     5761 tgctgaatct cttgaaaaaa cggtgaatct aattgaaata gaatacgagc cgcgatatcc
     5821 caataaagct ttatcgccaa cagatcgttt tgcccgggaa gtgcgccgat ctgtaatccg
     5881 gtccatgtat cttccatccg ctcctcatca cccagcacca ttttttgtga gagggctgga
     5941 gggcatgccg ggatgatttt tctttcagca tgataatccg gacgcttttc cagctggagg
     6001 tgaggaggca aaagcgtttc tgtattttct gagcccccaa tcaaaaacag cgtcatccga
     6061 tgggcttggt aggcagcctt ataggctttt tgtaaatcac tgatgtccag cgcctcaata
     6121 tcttcgattc tgcctgcggg gaaaacggca gctggtgagg agggagaaag catgctgatc
     6181 agctgataat gatatgagag ctgatggtta aggtgtgctg tttgaatttc gcttgtaatc
     6241 acagcttttt cctgagcgac aatcttcttg tcaaatgagt ggttccataa agcatcaagc
     6301 aggatgggga tcgtttgtct gagccgatcc ggtaatgagg taaacatgaa attggtatcg
     6361 gtgtaggtag tgaatgcgtt taaaagcgcg ccatgcgcaa aaaaatcact gtacagattg
     6421 cggccgttat gccagaagag aagatgctct aaaaaatgcg ctgtgccata cggaagcagt
     6481 gtatcaccgg attctgcccg tatacataca tcccggcttc caaaatcaat ttttacattg
     6541 cacagccgca ggtgggcgcg ggggaatttc aatctgaata tttttagtcc gctgtctgtg
     6601 tatctgatat cggttcgttc atccagttgt tgaaaaaagg ctttcttttc catctcttca
     6661 tccccttact acatgagctc cgatataatt gatggtcgct atgaattgca atacatcacg
     6721 gcatgtaacc gctgagatgc catccagcaa ggcttctttc gtgcaggaga agcggcgcag
     6781 gatccccata taggccaata gaccttcggg agaatcgaat tgcagcagca attcattgcg
     6841 taaaaactgc tttgcctgtt ctagttcccg ctcatctgta tgaaaagctg agacagcttc
     6901 caaaacgcgc gggggaatgt ctatctcatg aagctgatct gtacatattg aaacaagcag
     6961 caaattgttc atgacatcgt aacgggtgat aacgtgatag actgccagat ccttctctct
     7021 gaagtgcttg aataaagcgg aatggccgta ctttcccagt aatccgtcta ttagctgtat
     7081 tttgatataa tcgctggcat ctttcatctc tccgcagtca aatccgagtg tcaagacgga
     7141 aggacctgca gcgctgcgtg tctctgtttc aaacacatgc cggtttacgg gtattctttc
     7201 ggacgttaca gcggacgttt gcggggcatg tccccgaaca tcacatgctt gtacttgtcc
     7261 caatatgttc agctgttttt gctgggacac taaatcaacg ataaagtccg ttgcgtcgag
     7321 aaaccgttta ggatgaatcg cctttatcct gtctttccgg ccaaacatgc ctgtgccgta
     7381 catcgggttt ccgaagacct cctcagccaa gcgcgccgcc gagtaggaga aaggatcagt
     7441 gaatttcttt tcgattctca gcagcagctc attcctggcc ttttcaactg cttcgaatga
     7501 aagagaagaa gggaaagaca agtctgcaaa agttttcagc agggcgtcaa catgaagatt
     7561 cccgttatat aatgggtgaa tcaaacgggt cccgcaggtt ttcagctgct gatcaaaaaa
     7621 gagattcgct gagtacatga aacggctgcc ggcagcacaa ccgaaagcgt caataatttg
     7681 ctccttcagg tatgcggcgg cgccgtaaaa ataaatcgtt tcttcctcag gttccgccgc
     7741 gctttcgatc ggtttcagaa agctcgcggc gattgaaata gttgaaaatt gatgagtctt
     7801 cagcaggtta acttccaagc cgttctcttt tgcttgtatc aaagaaacca ccatcctgtt
     7861 tttgcaggta atagactatg accagaccgg ctatcggaat gaccgccaag gatacagcgg
     7921 tgccggctaa tgtggctaag aataggggaa gacaaaacag ataagaccga tattttgaga
     7981 aaccgctcca tagctgctgc tccgtctgcc agctgaagga gggccttttt tcatccgcag
     8041 ttaacctgat aaaagctccc gccagcagca actcaatgca ctgcaaaaaa gtgagaactg
     8101 aaatcggacg gccgctgatg aaacccacaa tcatcacgac aaggagaaat ccgcctgcca
     8161 ataggcctga ataaaagcga tatttcgccc aaaacatcgt tttccgcttg atcggaagcg
     8221 tgataagcag catccggtca tttttttcaa tcgaatacaa aagggcgatc ggcgagcaga
     8281 tgagcaaaag cgcggaaatc acgatataaa ccacttgctg attgaagatg ccggtattca
     8341 tcatctggaa cgaaaagaag ccgctgaacg ccgccattac cgcgtaattt aacagcatcg
     8401 ctttagaaga gataaatcgg ttccattctc ttttgtaaaa cgaaaattca gatcgccgca
     8461 taaatgaatg catcttgctc tgctgcggag gcgcctgcag aaagacagga aagtcaatga
     8521 tcaccgccca cagcatatgc accgcgcaaa gcggaagcgt ggcggccggc atcaaagcgg
     8581 cgctgataca tacacaggcg aatatcgccg catgcagcag aaacatcaag ttcttctttt
     8641 tgacgaagtg gttgcttagc acaactccga aaataatgga gtaaacggta aaaaacgaaa
     8701 acctgccgag ccaaaacaat gtttgcgccc ctgacagcgt tccgtttcca aataagaaca
     8761 gcggtaaaat aaaaaagaat aaagttcttc tcaaacaggt atcgacaaac aaaacgacac
     8821 tctgggcgag ccaaaagctc cgtgaagaaa tcggcagcag gcagctcagt ttcatataag
     8881 attccttcca ttgagatgtc acagaaagaa acaccatata tgcgttcatt aagagaagcg
     8941 cgagtatgat atacgttttg cgcaacaccg attcatcaat gccggcctgg cgaatcagcc
     9001 cgatttcaaa cacggccaga atgacaaggc ctgcggcaat gcggatggcg tcctttttcc
     9061 cttgccggct gtaaagctgt ttgaacagca aagacatgat ggggattatg ttattcatgg
     9121 ccgatcacct cgaaaaattc ccgccgcaga tcggtctcct ctccaatcgg aatgaccttt
     9181 tggatctgtt tgttgtgaag aatagccgcg taatcacaaa atctttgcac gacatcgagc
     9241 agatgagaag aaaacaaaat ggtcccgcct gcttcacagt actcgcgcat tttctgataa
     9301 aaaacctcta tcgattccac atccaaaccg acgagcggct catccaaaat aaacagggga
     9361 gcgcgcagca ataagcctgt catcaataca actttttgcc tgttccccaa ggacagctcc
     9421 gaaattctcc tgttgatgta ttttgaaaaa tgaaaggcct cggccaaact ggcaaactgc
     9481 tgctctgaaa aatccttttg ataaagcgaa tggacgaaag acatatagtc cttcgccgta
     9541 atttctgtaa atagcagcgg ataatcggcg gcgaagtaac ggtgagtctt cagctgatct
     9601 gatgttttct gcggcatgcc ggcctccgct tcaattccgc acagtgtaaa gcgcccgctg
     9661 aaattgcggt tcacgcctgt cagcgtatta atcagtgtcg tttttccggc gccgtttacc
     9721 ccaagcaacc cgtaaacggc gcctttttct aaatgtaaat ccacttgttc taagatgacg
     9781 ttgtcccgtt cataccaaac ggatacatcg tgtatatcca aaatgctcat cgcgagtcag
     9841 ccttccgcgc gcgcattccg aacagaatgg caatggcaat gaaaatcagc gtaaacagat
     9901 agtcgctttt gacaaaatag acgactgcgc cgatgacaaa gataaatgaa aggatataca
     9961 gtaaaattct tctttgtgct ggtgacaaat cgtttccctc ctaaataagc tggaccacgt
    10021 cttctaattg ttcatttttc gcccaagagc aaatgttttt ccggtgatat ttgttagagt
    10081 tcagcccttt taagtaacag cctccgcaat agccgctgaa cgggcatttg tctttcatgc
    10141 aatgttcgct gaaccgcggc gcttgcgctt gccacagttt atggacgaga ggggagttaa
    10201 agatgcttac ataggaatca tgaaaaatat ttcccaatga aaattccttt ggaaagaggg
    10261 cgcaaggacg tacttcgccg aacgggctga tcacaatgga cttccagcca gcgccgcaat
    10321 ttgccgcgcg ttttctctca tagggaataa tcggaatcag atctttaaac tcatcaatca
    10381 cattttgctc gtattccata aacttgcggt gctgctcggc gtctttcgtt ggatggacaa
    10441 tatctctgcc tcttccgaaa tcatcaaccc aattgtaaga aaacgccttc gccccgagat
    10501 cccgaacctt ttgggccata tcgtggattt cccacatgtt tttttcgaag acagacatgg
    10561 cgactctgac aaatataccg tggtcactca acaattttat cgttttacaa gtttgggcaa
    10621 aagagccttt tctccctcta aaggagtcat ggacctcgga attgacacta tcaagagaaa
    10681 tgccgacgat gattttttgc ttgtaagcct tcaaaagctc caaactctct tttcgcatga
    10741 gtgttccgtt tgttaagaca gcgacttttt tgaacttttt acacacatag tcaagaatct
    10801 cattggcatt tggatggaca aaaatttccc cacccgtgat ttcgcatgtc aatacaccgt
    10861 tatcaaacag catatcagcc gtttttttga attgctcaat cgacacggtg ccgagcgctt
    10921 caggtgagct ttccaaataa cagtgggcgc atttcaaatt acagcggtgc gtcagttcaa
    10981 aggtggcgtg caggggcatc ggaaattcat tgcttccgct cgtggtgatt gtatggcggc
    11041 tggcccggtt tccaagctgg atcacctgct tgttctggag catgttgagc atgtcgtaat
    11101 accaatcttt atggtcttcc ggtgattcat catacactgc acattgctca gctaaaatct
    11161 gctcagctgt tttttggcca tccatgcgca tgcagagctc gtaagccgtt ttgttgagat
    11221 ccaaatactc aaagtcagaa atggagacat tatcgcgcaa gtagtcgatt tctaacacgc
    11281 caccctcagg aagctggtga acccttacac tttcattaat aaatggaaac atctgctcta
    11341 taaacaaaat accatcccct atacatatga ttcaaatgaa aaacggttgt gtatgtatat
    11401 ccaagaggta gattttagtt aaaaattgta atttacttaa aaagggcata gtagaatgac
    11461 tatgcccttt tgggagatcc ttacccccat agaccgaata gacctgttgc accggcaatt
    11521 tcaaaatcag ggataggacc gtccactaga caagcggctc cgatcgagca tgttgcacaa
    11581 cctttgtttt ctacaatgac agcttttttc ataattgaat cctccctttt tttgtttttc
    11641 tagcagatct atgttgtact tttatcttaa aactatcaaa ttactaattc aatacatata
    11701 ttttgaaaaa aatgtgaaaa ggaaatgata gatttcggaa aaatgtaaca tttcctaaag
    11761 gtaattagtg atatgatttt ctcttctata taaggaaatg ctttttatga ggtttatctt
    11821 caaatctgat gagcaatgat ggtaagatag aagcagttga agtttacaaa ccgaatgatt
    11881 atactattca agtcaaagtg gaatgatgaa aaggacgtgt cagaatgaag caagagacac
    11941 cgataacact ccatgtgaag tctgtgatcg aggatgacgg aaaccaagaa gtcatcgaat
    12001 tccgcaccac cggattttac tatgtaaaac aaaataaagt gtatctatct tattatgaag
    12061 aacacgactt aggcaaagtc aaaacgattg tgaaagtaag cgaaggcgaa gtcctggtca
    12121 tgaggtcagg cgctgtcaaa atgaatcagc gtttcgtaac gggagcttcc acaattgcta
    12181 aatataaaat gtcatttggt gagcttgagc tgaaaacaag cacaaaatcg attcaatctg
    12241 atctcgatga agaaaaaggc cgtatcagca tcgcatatga catgcatgtc ggagacgagc
    12301 aggagcattt acataatatg acgatcacgt atgagggagg aactcacgca tgaacattgc
    12361 ggaacaaatg aaggacgtgc tgaaagaaga aatcaaagcg gccgttctga aagcgggact
    12421 ggctgaagaa agccagattc ccaatgttgt tttagaaaca ccgaaagata aaacacacgg
    12481 cgactactca acgaatatgg cgatgcagtt ggcaagagtg gcaaaaaaag cgccgcgtca
    12541 aatcgctgaa gagattgtcg ctcattttga taaaggaaag gcttcgattg aaaaactgga
    12601 tatcgccggc ccgggtttta tcaatttcta tatgaacaat caatatttaa caaagctgat
    12661 tccgtctgta ctggaagcag gggaagcata cggggaaacg aacatcggaa acggtgaacg
    12721 agttcaggta gaattcgtat cagcgaatcc gacgggagac cttcacctcg ggcatgcgcg
    12781 cggggcggct gtcggcgatt ccttgtgcaa cgtgctttca aaagcgggtt acgatgtaag
    12841 ccgcgaatac tacattaacg atgcgggaaa ccaaatcaac aatctggcgc tttctgttga
    12901 agtccgttac tttgaagcac tcggattgga aaaaccgatg ccggaggatg gctaccgcgg
    12961 tgaggatatc attgcgatcg gaaagcgtct cgctgaggaa tacggtgatc gtttcgttaa
    13021 cgaagaggaa agtgaacgcc tcgcgttttt ccgtgaatac ggcctgaaat acgagctgga
    13081 aaagcttcgc aaggacttgg aaaacttccg tgtgccgttt gatgtgtggt attcagaaac
    13141 ttcactgtac caaaatggaa aaatcgacaa ggcgcttgaa gcgctccgcg aaaaaggcca
    13201 tgtctatgaa gaagacggcg cgacttggtt ccgttccacg actttcggcg atgataaaga
    13261 ccgcgtattg atcaagaagg acggcacgta cacgtacctt cttcctgata tcgcgtatca
    13321 taaggacaag cttgaccgcg gctttgataa gctgatcaac gtttggggcg ccgatcacca
    13381 cggctacatc ccgcgtatga aagcggcaat cgaagcgctg ggctatgaaa aaggaacgct
    13441 tgaagtagaa atcattcagc tcgttcacct ttacaaaaac ggcgagaaaa tgaaaatgag
    13501 caaacggacc ggtaaagccg taacgatgcg tgacctgatt gaagaagtcg gcttggatgc
    13561 cgtgcgttac ttctttgcaa tgcgaagtgc agacacccat atggattttg acttagatct
    13621 tgctgtatca acatctaacg aaaaccctgt gtattatgca caatacgcgc atgcccgtat
    13681 ttgcagcatg cttcgccaag gggaagagca gggacttaaa ccggcggcag atcttgattt
    13741 cagccatatt caatcagaaa aagaatatga tctgctgaaa acgatcggcg gcttcccaga
    13801 ggcagtggcg gaagcagcgg aaaaacgaat tccgcaccgt gtcactaact atatttatga
    13861 tctggcttct gctctgcaca gcttctacaa cgcagagaaa gtcatcgacc ctgaaaatga
    13921 agagaaaagc cgcgcgcgcc tggctttaat gaaggcaacg caaattacgc tgaacaatgc
    13981 gcttcagctg atcggcgtat cggctccgga aaaaatgtaa tcacgatcaa aaggacaaag
    14041 tcttcgggct ttgtcctttt tttatgagaa aaacgtgtga tgtaattcac aatcctgttt
    14101 ggctagtttt tgtatgataa gactgattat tgaatcattg aaaggggcaa gccaaatgat
    14161 caaccgtcaa cacattcaat tatcgttaca gtcattaagc ttggtggcag ggtttatggt
    14221 ttgggtgctg atttcatcac tcatttccca aatcacatta gatattcatt taagcaaggg
    14281 tgagatttct ttggtgacgg cgattcctgt gatcctcggg tcgcttctcc gcattccttt
    14341 agggtattta acgaacaggt ttggcgcgcg gctcatgttt atggttagct tcatcctgct
    14401 tttatttcct gtattttgga tcagtatcgc ggattctctg tttgatttaa tcgcaggcgg
    14461 ctttttctta gggatcgggg gagcggtgtt ttccattggg gtgacctccc tcccgaaata
    14521 ttatccgaaa gaaaagcacg gtgtcgtcaa tgggatttac ggtgcaggaa atatcgggac
    14581 agccgttacg acatttgcag cgccggttat cgctcaagcc gtcgggtgga aatcaaccgt
    14641 gcagatgtat ctggttttgc tggctgtctt tgccttactg cacgttttgt tcggtgacag
    14701 gcatgagaag aaggtcaaag tttctgttaa gactcaaatc aaagccgttt accggaatca
    14761 tgtgctatgg tttctgagcc tgttttattt tattacgttc ggtgcctttg tcgccttcac
    14821 tatctatctg ccgaactttc tggtggagca ttttgggctg aatcctgcag atgccggctt
    14881 gcggacggct ggctttattg cggtttctac gctgctcagg cctgcaggcg gattcctggc
    14941 tgataaaatg agcccgctcc gcatcttgat gtttgttttt gccgggctta cattatcagg
    15001 cattatccta tcgttctcgc cgacaatcgg cctttatacg tttggatcat taaccgtggc
    15061 cgtctgctca ggcataggaa acgggactgt ttttaaactg gtgcctttct atttttcgaa
    15121 gcaagcgggg attgccaatg ggattgtgtc tgccatgggc ggattaggcg gcttttttcc
    15181 tccgctcata ttggcgagtg tatttcaggc aacaggccag tacgcgatcg ggtttatggc
    15241 gctttcagag gtggcgttag ccagttttgt ccttgtcata tggatgtatt ggcaggaaag
    15301 aatgaaaaca cacacggaga gaaacagcca gagcatcaac taacactggg gcattcacaa
    15361 gattgttagt tttttctcga tgggtacaaa tcaattcacg ttacaataaa cacacaacgt
    15421 gactttcttc gaggtgagct catgaatttt ctctctgttc gaccatctga tagtgatctt
    15481 atatccagcg atctgcatga actgctggaa tcgatcagca cgaaaagaaa aatggaaaaa
    15541 cacacgtatt tgtttcgaga aggaatggat gcagaagagc tttatctgat tcaatcagga
    15601 ctcattgaaa tcggcaagct gacatctgac ggaaaagacc tgacgcttag aatctgccaa
    15661 aagcatgata tcgtcggaga attaacactt ttcactgaag aaccgaggta tatgctcagt
    15721 gcaaaagtgc tagaggatgg cgaggtgctc gtcattaata aaaataagct ggaaaaagaa
    15781 ttaatccaaa acggcgcttt gacatttgag ttcatgaaat ggatgagcac gcacctccgg
    15841 aagattcagt ccaaaatcag ggatctgctt cttcatggca aaaagggggc gctctattcc
    15901 acccttatcc gtttatcaaa cagctacgga gtggagcgaa gcgacggcat tctgattaac
    15961 attgtcctga caaatcagga tttggcaaag ttttgcgcgg ctgcacggga aagcgtcaat
    16021 cgtatgctcg gagatctccg caaaaaaggg gttatttcga tagacgaatc cggaaaaatt
    16081 attttgcaca agcgggacta tttacgatgt gagattgagt gtgaaaattg cccgctggag
    16141 atttgcaata ttgactgaaa aaaacaagga cagcggtgtc cttgtttttt taccttgtga
    16201 taaacaggca catgacggca agaaagaagc aggcattcac gatttccaga atgccaatcg
    16261 tttttacggg ccaatccctt ccatgaaaaa accatgcccg caagctgctc gggataaaag
    16321 cgagaaacgc ccatcctgct ccgaaaagag cggataaaaa ggggagcagc aggtgatatc
    16381 cccatgacca gtatgcaaat gccctgtttt ttctctcgcg gatcaccgat ttcacataaa
    16441 aggaactccc gataaaaaat aaagcagact gcaagaaaat aaaccaagcc cagccgtcaa
    16501 gggttcccat ccccagccag cagctcgcaa acccgcccga acaaaagaac aagacacctg
    16561 caacatcatt caataaggct cgttcgtttt ttctgcgggc aaaatacata tgtatgagaa
    16621 acagcggcag taaagaaacg cccacccaga tgagaggcgg cttatgaaag accgagatca
    16681 tcaaaaagca gcaggcggga aaaccgtaat aacacatcca cttttgatat ggtttgcttt
    16741 gtttcttttt taaggcaagc gtaacgggat aaaccgctaa gtataggaaa agccaaccaa
    16801 ggaagagcgg aatatgccaa ataacggggc ctcccttgac catgccgagt aaaaatggga
    16861 tcagcagcat cgcccacgcc ccgtgctgct tcggaatcag cgccttcatc gaaatcctcc
    16921 ttttttcttt cattataaat gcattcaccc tcctgataag tgacattcat catacaggct
    16981 gtgaaataca tcactgctgt acaggctcag tcgagctaca ctaaagctat ccttagcaca
    17041 ggaggttttc ctatgaatca gtgtgactat ttattatttc tgaaacaact tcctatgttt
    17101 aatgaagtgc ctctatccat tgtcgaaacc ttgctgaaaa acggcacgtt tatccgcggt
    17161 tcatgtgatc agtctccatc ttttcttcat tctcaatctg tttatattgt attaaaaggc
    17221 agtgtccgtt ttatggacac aaggctccct gaagggtcga aaaccgttgc gctgtgggaa
    17281 aaaggcgatg tgtttccgat tgatgaaaaa ggcgggcttt atttatcgcc ctttatctca
    17341 gtcaatgcca cttcagacat tctgattctc aacatcccat attacatatt taagaaaatg
    17401 atgtcttatc atccgcagct gcaaatgaac tttttggcta tgcttcagca aaatgttttt
    17461 tgttcctatc aattattttt gcggtatctg catacatcac aggatgaaaa cgctgagccc
    17521 ggttcttaaa tagagccggt ttttttgtct ttgaatgaaa ggcagctaat gacccaagcg
    17581 tcctgcctga acgcagcctt ccttctcctt tgtgtggaca ttttgtgaaa aaagcagagt
    17641 gtgtgacata gttcacaagg aaacgcgctg tctctgttta tagtgaactt agcatcacct
    17701 gactcggaag gagtgaactc tcatgaagaa aaagaaaagg agtccgttgt ttaggagatt
    17761 gaattatttc tctcctatcg aacaccattc aaataaacat agccaaacca cccgcgaaga
    17821 tcgcgattgg gagaatgtat acagaaacag atggcagtac gacaaagtcg ttcgctccac
    17881 ccacggcgtt aactgtacag ggtcttgcag ctggaatatt tatgtgaaaa acggaattgt
    17941 cacgtgggaa gggcaaaatt tgaattatcc ttcaacaggc ccggatatgc ctgattttga
    18001 accgagaggc tgcccgcggg gggccagttt ttcatggtat atctacagcc cgctgcgtgt
    18061 gaaatattca tacgtgcgcg gtgtactgat taatttatgg cgggaggcac tgcaagaaca
    18121 tcaaaatcca ttggaagcct ggaaatcgat cgtcgaaaac cctgaaaaag cgaagtccta
    18181 taaacaggcg agagggaaag gcggttttgt gcgcgctgaa tggccggagg tgctgaagct
    18241 gatttcagcc tctctgctgt atacagtgat gaaatacggg cctgacagaa acgtcggttt
    18301 ttctccgatt ccggccatgt ccatgatcag ccatgcatca ggctcccggt ttatgtcgtt
    18361 aatcggaggc cctatgctca gtttttatga ctggtatgcg gatcttcctc cggcatcccc
    18421 gcaaatttgg ggtgaccaga cggacgttcc ggaaagcagt gattggtaca attccggcta
    18481 tatcatcaca tggggctcca acgttccgtt aacgagaacg cctgacgcgc attttttggc
    18541 ggaggcccgc tataaaggcg ctaaggtcat ttcgatcagt ccggattttg cggaatcctc
    18601 aaagttcgcg gatgactggc tgagtattcg ccaagggact gacggggcgc ttgcgatggc
    18661 gatgggtcac gtcattctgc aggaatttta cgtgaaccaa gaaactgaac gttttattga
    18721 gtacgcgaag caatacactg attttccatt tctcgtcacc ctgtcaaaag aaaatggcgt
    18781 atacacagcg ggacggtttc tgcatgcgaa ggacatcggg cggaagacaa agcatgatca
    18841 gtggaagcct gcggtttggg atgaacagac aagttcattt gccatacccc aagggacaat
    18901 gggctcgcgc tgggacgggc agcagaaatg gaacctgcac atgattgatg aagaaaccgg
    18961 ggaaccgatt gaaccctgtc tctctgtgct gggaatagag gacgaaatcg gcacggtgcg
    19021 catcccgtat ttttcaaatg acggaaacaa agtgctcgag cgggatcttc ctattaaaaa
    19081 aatgaacctg aacggtgaag aaacgtacat cacgaccgtg tttgacttga tattggctaa
    19141 ctacggcgtg aaccggggca tcggtaaacg atcggctgtc tcctatgatg atcctgagcc
    19201 gtttacgcct gcctggcagg aacaaatgac aggaatcaaa aaagaagctg tcgttaagat
    19261 tgccagagag tttgcccaaa atgcgatcga tacagacggc cggtccatga ttatcgtagg
    19321 ggccggcatt aaccactggt tcaactccga cacgatctac cgagcggtgt taaatcttgt
    19381 tttacttgta ggcgcccaag gcgtaaacgg cggaggctgg gcccattacg tggggcagga
    19441 aaagctccga cctgctgaag ggtggcagac gattgcaact gcaaaggact gggagggcgt
    19501 gcctaagctg caaaacggca cctcattttt ctactttgcg acagatcagt ggcgttatga
    19561 ggaccagccg atcagtgatt tggcatcgcc gattgctgcg tcatcccgct acaagcacca
    19621 cgctgattac aatgtgctgg ccgcgcggct ggggtggctt ccgtcttacc cgactttcaa
    19681 tcaaaatggc atcgatctgt ataaagaagc tgaaaaagca ggggcagcaa cacctgaaga
    19741 cgttggtgcg tacgtggcct cacagctcca agagaaaaaa ctgaaattcg cgattgaaga
    19801 tcctgataat gaagtgaatt ttccaagaaa tctcttcgta tggcgggcaa atctgatctc
    19861 aagctcagga aaagggcatg aatattttct caagcatttg ctggggacga cgaacggttt
    19921 aatgaatgac gatagcgaca gcatccgccc tgaagaaatc aaatggcggg agcaggcgcc
    19981 ggaaggaaag ctcgacttgt taatcaatct tgacttccga atggccggta cggcgctgta
    20041 ttccgatatc gtgctgccgg cggcgacatg gtatgaaaaa cacgatctca gcagcacaga
    20101 tatgcacccg ttcattcatc catttgctcc ggcgatctcg gctccgtggg aatcgaagtc
    20161 agactgggat attttcaagg cgctgtcaaa agccgtttcc gatctggcag aagaagtcga
    20221 tatggagccc gtgaaagaag tggttgcgac gccgctcctc cacgacacca tgcaggaatt
    20281 ggcccagcca ttcggcaaaa tcaatgactg gagcaaaggc gaatgtgaag ccattccggg
    20341 aaaaacgatg ccgaacatcc aagtcgttga acgggattac aaacacattt ttcataaaat
    20401 gactgcactt ggtccgaacg ttgctttaaa gccgagcgga acaaaaggga tgagctggtc
    20461 aatagccgat gaatatgaat cactcaaaca gagattggga gaaatcacct cggacagtgt
    20521 cgcaaaggga tgtccaaata taagtgaagc aaagcaggca gcagaagcga ttttaaccct
    20581 atcatccact tcgaatggaa aggtcgccgt caaagcatgg gaatcacttg aaaacatcac
    20641 gaacctgaag ctgaaagacc tggcggaaga acgcgaggaa gaatgcttta cgttcgaaca
    20701 aattacagcc cagccgaaaa cggtgatcac gtctccagcg ttttccggct ctgaaaaagg
    20761 agggcgcagg tattcgccgt ttacgacgaa tgttgaaaaa ttaatcccgt ggcggacgct
    20821 gacaggcaga caatcctatt atgtcgatca tgaactgatg atggaattcg gtgaaacgat
    20881 ggcgacattc aaaccgatcc tccagcatcg cccgtttctg agcaagcggc ctgatcaaga
    20941 gggaaaagaa atcgtcctca attatttgac gccgcataat aaatggtctg tccacagcat
    21001 gtattttgat tctctgccaa tgctgacgct gttccgcggt gggccaaccg tgtggatgaa
    21061 taaagatgat gcagaggaca cggatatcaa agacaacgat tggattgaat gctttaaccg
    21121 aaacggtgtt gttgtcgcga gagccgtttt gtctcatcgg attcctaaag gaatggcgtt
    21181 tatgcaccat gcccaggacc gccacatcaa cgtgcccggc acaaagctga cgaataaccg
    21241 cggaggcacc cataacagcc cgacaaggat tcacgtcaag ccgacacaga tgatcggtgg
    21301 ctacgcccag ctcagctacg gctttaatta ttacggtcca acggggaatc agcgcgacct
    21361 gaacgtcgtc atccgcaagc tgaaggaggt cgattggctt gaagattaaa gcgcaaatcg
    21421 gtatggtcat gaacttggat aaatgcatcg gctgccacac gtgcagcgtc acctgcaaaa
    21481 acacgtggac aaaccgttcc ggtgcggaat atatgtactt caataatgta gaaacaaagc
    21541 cgggcatcgg ctacccgaag caatgggagg accaggacaa atataaaggc ggctggacat
    21601 tgaaaaaagg aa
//
