LOCUS       gnlProkkaGKAFKPJL_63    3849 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GKAFKPJL_63.
ACCESSION   gnlProkkaGKAFKPJL_63
VERSION     gnlProkkaGKAFKPJL_63
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:33:48
            Original ID  :: gnl|Prokka|GKAFKPJL_63
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3849
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..771)
                     /NRPS_PKS="Domain: PP-binding (166-232). E-value: 2.5e-14.
                     Score: 45.5. Matches aSDomain:
                     nrpspksdomains_ctg53_1_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_1"
                     /sec_met_domain="PP-binding (E-value: 9.1e-16, bitscore:
                     45.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGLTTLYRHVCNEPLQFFVLFSSVSAIIPELSAGQADYAMANSY
                     MDYFAEAHQKHVPIISVQWPNWKETGMGEVTNQAYRESGLFSITNSEGLRFLDQIVSKM
                     FGPVVLPAMANQTNWEPELLMKRRKPHEGGLQEAALQSPPARDFEEADEVSKCDGLLSE
                     TQSWLVDLFTEELRIDREDFEIDGVFQDYGVDSIILAQVLQRINRKLEAALDPSILYEY
                     PTIQRFADWLIGSYSERLSALFGGRISDASAPLEN"
     protocluster    1..3849
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[796:3847]"
                     /cutoff="45000"
                     /detection_rule="cds(ATd and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS) and not PKS_AT)"
                     /neighbourhood="20000"
                     /product="transAT-PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      797..3847
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="45000"
                     /detection_rule="cds(ATd and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS) and not PKS_AT)"
                     /neighbourhood="20000"
                     /product="transAT-PKS-like"
                     /protocluster_number="1"
     cand_cluster    1..3849
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(ATd and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS) and not PKS_AT)"
                     /kind="single"
                     /product="transAT-PKS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3849
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="transAT-PKS-like"
                     /region_number="1"
                     /rules="cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS
                     or itr_KS or tra_KS) and not PKS_AT)"
                     /tool="antismash"
     aSDomain        complement(76..273)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg53_1_PP-binding.1"
                     /evalue="2.50E-14"
                     /label="ctg53_1_PP-binding.1"
                     /locus_tag="ctg53_1"
                     /protein_end="232"
                     /protein_start="166"
                     /score="45.5"
                     /tool="antismash"
                     /translation="WLVDLFTEELRIDREDFEIDGVFQDYGVDSIILAQVLQRINRKLE
                     AALDPSILYEYPTIQRFADWL"
     aSModule        complement(76..3625)
                     /complete
                     /domains="nrpspksdomains_ctg53_2_PKS_KS.1"
                     /domains="nrpspksdomains_ctg53_2_Trans-AT_docking.1"
                     /domains="nrpspksdomains_ctg53_1_PP-binding.1"
                     /locus_tags="ctg53_1"
                     /locus_tags="ctg53_2"
                     /monomer_pairings="mal -> mal"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(616..726)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg53_1_0001"
                     /evalue="3.10E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg53_1"
                     /protein_end="52"
                     /protein_start="15"
                     /score="45.4"
                     /tool="antismash"
                     /translation="LQFFVLFSSVSAIIPELSAGQADYAMANSYMDYFAEA"
     CDS             complement(797..3847)
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (74-513). E-value:
                     4.5e-172. Score: 564.5. Matches aSDomain:
                     nrpspksdomains_ctg53_2_PKS_KS.1"
                     /NRPS_PKS="Domain: Trans-AT_docking (526-681). E-value:
                     2.7e-65. Score: 211.3. Matches aSDomain:
                     nrpspksdomains_ctg53_2_Trans-AT_docking.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS-like: tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS-like: ATd"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 244.3; E-value:
                     4e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_2"
                     /sec_met_domain="tra_KS (E-value: 1.7e-194, bitscore:
                     633.5, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ATd (E-value: 9.8e-67, bitscore: 211.3,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFFEYGSIQSLAEYLTAEHEDTLVQEREKPEGQEELQTKSPEAPK
                     ITSRRKRRFTQPVIAKAERNKKQAADFEPVAIVGISGRFPGAMDIDEFWKNLEEEKDSI
                     TEVPKDRWDWREHYGNPDTDVNKTDIKWGGFIDGVAEFDPLFFGISPREADYVDPQQRL
                     LMTYVWKALEDAGCSPQSLSGTGTGIFIGTGNTGYKDLFHRANLPIEGHAATGHMIPSV
                     GPNRMSYFLNIHGPSEPVETACSSSLVAIHRAVTAMQNGDCEMAIAGGVNTILTEEAHI
                     SYSKAGMLSKDGRCKTFSADANGYVRGEGVGMVMLKKLEDAERDGNHIYGVIRGTAENH
                     GGRANTLTSPNPKAQADLLVRAYRQAGIDPSTVTYIEAHGTGTELGDPIEINGLKAAFK
                     ELSNMRGESQPDVPDHRCGIGSVKSNIGHLELAAGISGLIKVLLQMKHKTLVKSLHCET
                     LNPYLQLTDSPFYIVQEKQEWKSVTDRDGNELPRRAGISSFGIGGVNAHIVIEEYMPKA
                     NSEHTATEQPNVIVLSAKNKSRLIDRASQLLEVIRNKKYTDQDLHRIAYTLQVGREEMD
                     ERLACVAGTMQELEEKLQAFVDGKEETDEFFRGQSHRNKETQTIFTADEDMALALDAWI
                     RKRKYAKLADLWVKGVSIQWNTLYGETKPRLISLPSYPFAKDYYWVPAKEHSERDKKEL
                     VNAIEDRAACFLTKQWSLSPIGSAVPGTRTVAILCNQETADLAAELSSYFPNHLLLDVS
                     RIENDQSDIDWKEFDGLVDVIGCGRDDEGRLDWIEWVQRLVEFGHKEGLRLLCVTKGLE
                     SFQNTSVRMAGASRAGLYRMLQCEYSHLISRHMDAEEVTDHPRLAKLIADEFYSESYDA
                     EVCYRDGLRYQAFLKAHPETGKATEQSTVFPKDHVLLITGGTRGIGLLCARHFAECYGV
                     KKLVLTGREQLPPREEWARFKTSNTSLAEKIQAVRELEAKGVQXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXSDGYGYAGIYPKNFR"
     CDS_motif       complement(1034..1126)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg53_2_0005"
                     /evalue="6.30E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg53_2"
                     /protein_end="938"
                     /protein_start="907"
                     /score="28.4"
                     /tool="antismash"
                     /translation="LITGGTRGIGLLCARHFAECYGVKKLVLTGR"
     aSDomain        complement(1805..2269)
                     /aSDomain="Trans-AT_docking"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg53_2_Trans-AT_docking.1"
                     /evalue="2.70E-65"
                     /label="ctg53_2_Trans-AT_docking.1"
                     /locus_tag="ctg53_2"
                     /protein_end="681"
                     /protein_start="526"
                     /score="211.3"
                     /tool="antismash"
                     /translation="PNVIVLSAKNKSRLIDRASQLLEVIRNKKYTDQDLHRIAYTLQVG
                     REEMDERLACVAGTMQELEEKLQAFVDGKEETDEFFRGQSHRNKETQTIFTADEDMALA
                     LDAWIRKRKYAKLADLWVKGVSIQWNTLYGETKPRLISLPSYPFAKDYYWV"
     aSDomain        complement(2309..3625)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg53_2_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /domain_subtypes="red/shDB"
                     /evalue="4.50E-172"
                     /label="ctg53_2_PKS_KS.1"
                     /locus_tag="ctg53_2"
                     /protein_end="513"
                     /protein_start="74"
                     /score="564.5"
                     /specificity="transATor: red/shDB"
                     /tool="antismash"
                     /translation="VAIVGISGRFPGAMDIDEFWKNLEEEKDSITEVPKDRWDWREHYG
                     NPDTDVNKTDIKWGGFIDGVAEFDPLFFGISPREADYVDPQQRLLMTYVWKALEDAGCS
                     PQSLSGTGTGIFIGTGNTGYKDLFHRANLPIEGHAATGHMIPSVGPNRMSYFLNIHGPS
                     EPVETACSSSLVAIHRAVTAMQNGDCEMAIAGGVNTILTEEAHISYSKAGMLSKDGRCK
                     TFSADANGYVRGEGVGMVMLKKLEDAERDGNHIYGVIRGTAENHGGRANTLTSPNPKAQ
                     ADLLVRAYRQAGIDPSTVTYIEAHGTGTELGDPIEINGLKAAFKELSNMRGESQPDVPD
                     HRCGIGSVKSNIGHLELAAGISGLIKVLLQMKHKTLVKSLHCETLNPYLQLTDSPFYIV
                     QEKQEWKSVTDRDGNELPRRAGISSFGIGGVNAHIVIEEY"
     CDS_motif       complement(2546..2590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg53_2_0004"
                     /evalue="6.80E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg53_2"
                     /protein_end="434"
                     /protein_start="419"
                     /score="12.1"
                     /tool="antismash"
                     /translation="GSVKSNIGHLELAAG"
     CDS_motif       complement(2678..2725)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg53_2_0003"
                     /evalue="6.40E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg53_2"
                     /protein_end="390"
                     /protein_start="374"
                     /score="14.7"
                     /tool="antismash"
                     /translation="YIEAHGTGTELGDPIE"
     CDS_motif       complement(2918..2956)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg53_2_0002"
                     /evalue="9.50E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg53_2"
                     /protein_end="310"
                     /protein_start="297"
                     /score="15.3"
                     /tool="antismash"
                     /translation="FSADANGYVRGEG"
     CDS_motif       complement(3098..3145)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg53_2_0001"
                     /evalue="3.00E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg53_2"
                     /protein_end="250"
                     /protein_start="234"
                     /score="16.2"
                     /tool="antismash"
                     /translation="GPSEPVETACSSSLVA"
ORIGIN
        1 gttctccaaa ggtgctgatg catccgatat cctgcctccg aataaagcgg acagcctttc
       61 ggaataagaa ccgatcagcc aatctgcgaa cctttgaatt gtcgggtatt catatagaat
      121 cgatggatcg agcgctgcct ctaatttgcg gtttatacgc tggagcacct gtgccaaaat
      181 gatcgaatcc acgccataat cctgaaacac cccgtcaatc tcgaagtctt cacgatctat
      241 tctcagctct tcggtaaaca gatcaacaag ccaggactgt gtttcagata ataatccatc
      301 acatttggaa acttcatcgg cctcttcaaa gtctctggct ggcgggctct gtaaagcagc
      361 ttcctgcaaa ccgccctcat gcggtttcct cctcttcatc agcagttccg gctcccagtt
      421 tgtttgattc gccattgcag ggagaacaac cggtccgaac attttcgata caatttgatc
      481 tagaaaacgt aagccttctg aattcgtaat gctgaacaag ccgctttccc gatacgcttg
      541 atttgtcact tcacccatac cggtttcttt ccagttcggc cactgaacac tgatgatcgg
      601 cacatgtttc tgatgtgctt ctgcaaaata atccatatag ctattggcca tcgcatagtc
      661 agcttgtccc gccgaaagct ccggaataat ggctgaaaca gaagaaaata agacaaaaaa
      721 ctgtaaaggc tcgttacaca catggcgata taacgttgta agacctgaca ccttaggttc
      781 catcacccgc tggatatcat ctgaagtttt tcggataaat gccagcgtat ccatatccgt
      841 cagaccnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      901 nnnnnnnnnn nnnnnnnnnn nnnnnnncct gtacaccctt cgcttccagc tccctcactg
      961 cctggatttt ctctgccaat gatgtgtttg atgtcttaaa acgcgcccac tcctctcgcg
     1021 gaggaagctg ttctcgtccg gtcagcacca gttttttcac tccatagcac tctgcaaaat
     1081 gacgggcgca taatagtccg atgcctcgtg tgccgcctgt aatgagaagt acatgatctt
     1141 tcgggaagac cgtgctttgt tccgtggcct tacctgtttc cggatgagct tttagaaaag
     1201 cttggtaccg taaaccatcc ctgtagcaaa cctccgcatc ataagattcg gaataaaact
     1261 catcagcgat caacttcgcg agacggggat gatcagtaac ctcctcagca tccatatgcc
     1321 ttgatataag atggctgtac tcgcattgga gcattcgata caacccagcc cgtgaggcgc
     1381 cagccatccg gacagatgtg ttttgaaacg attcgagccc cttcgtcaca caaagcagcc
     1441 tgagcccctc tttatgcccg aattcaacca gtctttgcac ccattcaatc caatccagcc
     1501 ggccctcatc atccctaccg catccgatga catccactag gccgtcaaac tctttccaat
     1561 caatgtctga ctgatcattt tctatccggc tcacatctaa taagagatga ttcggaaaat
     1621 acgaagacaa ttctgctgct aaatctgctg tctcttgatt gcacaggatg gcaacggttc
     1681 ttgtccccgg cactgctgag ccaattggac tcaaactcca ttgtttcgtc aaaaagcatg
     1741 cagcccgatc ttcaatcgca ttaaccagtt cttttttgtc tctttctgaa tgttcctttg
     1801 ccggcaccca atagtaatcc ttcgcaaacg gatatgaagg gaggctgatc aggcgcggtt
     1861 tggtctctcc gtataatgtg ttccactgga ttgagacccc tttgacccat aaatcagcaa
     1921 gtttggcgta ttttcttttt ctgatccaag catcaagtgc caacgccata tcttcatctg
     1981 ctgtaaaaat agtctgggtc tctttatttc gatgagactg tccccggaaa aattcgtctg
     2041 tttcttcctt accgtcaaca aacgcctgca gtttctcttc aagctcctgc attgtccccg
     2101 caacacacgc cagacgctca tccatttctt cgcgcccgac ctgcagggtg taagcgatgc
     2161 ggtgcaaatc ctgatctgta tattttttat tgcgaatcac ctcaagcaat tgcgaagcac
     2221 gatctatcag cctgctttta tttttagccg acagcacaat tacgtttggc tgttctgtag
     2281 ccgtgtgttc tgaattggct tttggcatat attcttcaat cacaatatgc gcgtttactc
     2341 cgccaatccc aaacgaactg attccggcac ggcgcggaag ctcgtttccg tcacgatctg
     2401 tgacagactt ccattcctgt ttttcctgaa cgatgtaaaa cggactgtca gtcagctgaa
     2461 gataaggatt aagcgtctcg caatgcaggc ttttcactaa cgttttatgc ttcatttgca
     2521 aaagcacctt gatcaaaccg gaaataccgg ctgctagctc taaatgaccg atattgcttt
     2581 taactgagcc gatgccgcaa cggtgatccg gaacatccgg ctggctctcg cctctcatat
     2641 tggatagttc cttaaacgcg gctttcagcc catttatttc aatcggatcg cccaattccg
     2701 tccctgttcc atgtgcttcg atatatgtga cagtgcttgg atctatgcct gcttggcgat
     2761 atgcacgcac caacaaatca gcttgtgctt tcggattagg cgatgtcagg gtattggctc
     2821 ttccgccgtg attttccgcc gtcccccgaa taacgccgta aatatgattt ccgtcgcgct
     2881 cggcatcttc cagctttttc aacatgacca ttccgacccc ttcgcctctg acatagccat
     2941 tcgcatcggc agagaaggtt ttacacctgc cgtctttgct gagcatcccc gccttgctgt
     3001 agctaatatg cgcctcctcg gttaagatcg tattcacgcc tccagcgatc gccatctcac
     3061 aatcaccgtt ttgcatcgca gtcacagcac ggtgaatggc tacaagagaa ctggaacaag
     3121 ccgtctctac tggctcgctc ggaccatgaa tatttaaaaa ataactcatt ctattcgggc
     3181 ctaccgaagg aatcatatga cctgtagcag catggccttc aattggaaga ttcgctctat
     3241 ggaatagatc tttataaccg gtgtttcccg taccgataaa gataccagtc cctgtacccg
     3301 aaaggctttg cggcgagcaa cccgcatctt ccagtgcctt ccacacgtat gtcattaaca
     3361 agcgctgctg agggtctaca taatcagctt ctcgcggcga aataccaaaa aacaacggat
     3421 caaactctgc gacaccatca ataaacccgc cccatttgat gtcagtttta ttgacgtcag
     3481 tgtctgggtt tccataatgc tcccgccaat cccatcgatc ttttggtact tctgtgatgc
     3541 tgtctttttc ttcttctagg tttttccaaa attcgtctat atccatagcg ccagggaatc
     3601 ggccgctgat gccgacaatt gcaaccggct caaaatcggc agcctgcttt ttgtttcttt
     3661 ctgcttttgc aataacaggc tgtgtaaagc ggcgctttct acgtgatgtg attttcggcg
     3721 cttcagggga ttttgtctgt aactcttcct gtccctctgg tttttcgcgc tcctgaacca
     3781 gggtgtcctc atgttcagca gtcaaatact cagccaggct ttggatgctt ccatattcaa
     3841 agaaaatgg
//
