LOCUS       c00002_gnlPro..        22166 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MANCPEPA_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 20:57:02
            Original ID  :: gnl|Prokka|MANCPEPA_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 657107
            Orig. end    :: 679273
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..846
                     /locus_tag="ctg2_692"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     protocluster    1..22166
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[666780:670017]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9674..12910
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..22166
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22166
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="fatty_acids-unassigned"
                     /region_number="2"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             944..1393
                     /locus_tag="ctg2_693"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEMMGTICGDDTILIICRTPEDTEGVKNRLLELL"
     CDS             1430..3160
                     /locus_tag="ctg2_694"
                     /transl_table=11
                     /translation="LLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQQISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKMSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAENVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     CDS             3334..4614
                     /locus_tag="ctg2_695"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQTSESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYGKEKAS"
     CDS             4890..5693
                     /locus_tag="ctg2_696"
                     /transl_table=11
                     /translation="VEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     CDS             6002..6115
                     /locus_tag="ctg2_697"
                     /transl_table=11
                     /translation="MKKKKARKREGFFLDFLFEVGGELFLLLFRCVHKLFI"
     CDS             complement(6158..7306)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_698"
                     /sec_met_domain="Oxidored_FMN (E-value: 5e-123, bitscore:
                     407.7, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRIQTKEDDQMNPKYKPLFEPFTFKSGVTINNRIAVAPMTHYASN
                     EDGTISEAELDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLTQAI
                     QAQGAKAVVQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALKEEEVENIVKAFGE
                     ATRRAIEAGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKA
                     ASEHAKGAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRG
                     ADPTRTRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPDWTVK
                     VKEGREKQIETVIKGTDKEKYHLPEPLWQAIVNTPGWVPYKD"
     CDS             7809..8102
                     /locus_tag="ctg2_699"
                     /transl_table=11
                     /translation="VKQTVLLLFTALFLSGCSVASADDSVPRFTEEGKYIGSADPHTIA
                     VSLNGEETMIQVPKDKRDECESLPDQTHVLVKYTKKDNGTLQLEDIQLRKNS"
     CDS             8123..8737
                     /locus_tag="ctg2_700"
                     /transl_table=11
                     /translation="MLWRSLALCGLALTLAPCAQAAEPIEGKTVYIDAGHGGEDSGAVG
                     NGLFEKDINLSVSEHVTDKLKEEGANPVASRSDDHFLTLEERVAKASANQADLFVSIHV
                     NSGVASASGTETYFQSDYEGESSRRLASDIQSELVSSLQTRDRGVKESDFYVITYSQMP
                     SVLAELGFITNSSDADKLGSEEYQQKAADAIVNGIDSYYDQ"
     CDS             8816..9547
                     /locus_tag="ctg2_701"
                     /transl_table=11
                     /translation="MTKIFAHRGASGQFPENTMLAFEKGIEAGADGIELDVQLTKDGRI
                     VVIHDERLNRTTSLKGFVKDTAYDEVKTANAAAGHDQAYSDIKVPLLEDVLSWAVKKDF
                     LINIELKNSVIRYEGMEEKVLEAVKRFNVEDRVILSTFNHDSLALCARLAPHIERAVLT
                     SDVLYQADRYIASIPASGYHPKLNSPGVTDEVLKKMRNGLIKVRPYTVNRPEDMKRLIE
                     AGADGMFTDFPEKASALLKNE"
     CDS             9674..10855
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_702"
                     /sec_met_domain="Thiolase_N (E-value: 9.4e-103, bitscore:
                     340.0, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 9.5e-50, bitscore:
                     164.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQRAGVSG
                     DDVEGNVMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRA
                     QDADILVAGGMESMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNT
                     AAKEYAISRREQDEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRR
                     DTSLDQLAKLAPIYASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFST
                     TGMPAHELAAAPGFAINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNV
                     NGGAIALGHPIGASGARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQVH"
     CDS             10880..11743
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_703"
                     /sec_met_domain="HCDH (E-value: 5.3e-38, bitscore: 126.5,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.6e-67, bitscore: 223.9,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQIMVAGAGQMGSGIAQTAADAGFYVRMYDVNPEAAEAGLKR
                     LKKQLARDAEKGKRTETEVKSVINRISISQTLEEAEHADIVIEAIAENMAAKTEMFKTL
                     DRMCPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFMNPVPVMKLVEVIRGLATSEET
                     ALDVMALAEKMGKTAVEVNDFPGFVSNRVLLPMINEAIYCVYEGVAKPEAIDEVMKLGM
                     NHPMGPLALADFIGLDTCLSIMEVLHSGLGDSKYRPCPLLRKYVKAGWLGKKSGRGFYD
                     YEEKTS"
     CDS             11771..12910
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_704"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.4e-56, bitscore:
                     186.2, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.5e-28, bitscore:
                     94.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.4e-39, bitscore:
                     129.6, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGK
                     HGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQ
                     KMKYIPKLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADI
                     YITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANL
                     LGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISF
                     KLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYG
                     YMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT"
     CDS             12944..14062
                     /locus_tag="ctg2_705"
                     /transl_table=11
                     /translation="MEEKQHYSPGLDGVIAAETHISYLDTQSSQILIRGYDLIELSETK
                     SYLELVHLLLEGRLPEESEMETLERKINSASSLPADHLRLLELLPEDTHPMDGLRTGLS
                     ALAGYDRQIDDRSPSANKERAYQLLGKMPALTAASYRIINKKEPILPLQTLSYSANFLY
                     MMTGKLPSSLEEQIFDRSLVLYSEHEMPNSTFAARVIASTHSDLYGALTGAVASLKGNL
                     HGGANEAVMYLLLEAKTTSDFEQLLQTKLKRKEKIMGFGHRVYMKKMDPRALMMKEALQ
                     QLCDKAGDHRLYEMCEAGERLMEKEKGLYPNLDYYAAPVYWMLGIPIPLYTPIFFSART
                     SGLCAHVIEQHANNRLFRPRVSYMGPRYQTKS"
     CDS             14077..15495
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MmgE_PrpD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_706"
                     /sec_met_domain="MmgE_PrpD (E-value: 2.7e-151, bitscore:
                     501.0, seeds: 231, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKTDRVIEEITDYVLEKEITSAEAYTTAGHVLLDTLGCGILALR
                     YPECTKLLGPIVPGTTVPNGSKVPGTSYVLDPVRAAFNIGCMIRWLDYNDTWLAAEWGH
                     PSDNLGGILAAADYVSRVRLSEGKEPLTVRDVLEMMIKAHEIQGVLALENSLNRVGLDH
                     VLFVKVATTAVAAKLLGGGREEIKNALSNAWIDNAALRTYRHSPNTGSRKSWAAGDATS
                     RGVHLALMSLKGEMGYPTALSAPGWGFQDVLFNKKEIKLARPLDAYVMENVLFKVSYPA
                     EFHAQTAAESAVILHPQVKNRIDEIDRVVIRTHESAIRIIDKKGPLHNPADRDHCLQYI
                     TAIGLLFGDITAQHYEAETASDPRIDKLRDKMEVTENKTYTEDYLKPDKRSISNAVQVH
                     FKDGTSTEMVECEFPLGHRFRREEAVPKLLEKFSDNLKTHFPDKQHKHIYERCTSYETL
                     QTMRVNEFVDMFCM"
     CDS             15512..16417
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_707"
                     /sec_met_domain="PEP_mutase (E-value: 6.4e-55, bitscore:
                     183.2, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEA
                     GFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAA
                     RTAREMLEARVAAVQIEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQAAPSLIVVART
                     DARAQEGLAAAIKRSEAYIEAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTP
                     YYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTI
                     SYYDYEALDKTIAKTVLPDE"
     CDS             complement(16459..16695)
                     /locus_tag="ctg2_708"
                     /transl_table=11
                     /translation="MSRLLALLILVIPGAISALGIKLMRDTLFGHTIKPFSALWLQGLS
                     GFIFFAIGLYVLAGFILYRDRKRNQVSPRFRKR"
     CDS             16848..18926
                     /locus_tag="ctg2_709"
                     /transl_table=11
                     /translation="MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDSEAPGLKEAE
                     QYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLMEE
                     KQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGRPIK
                     EVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAV
                     ELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPA
                     NTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVS
                     EIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESG
                     TGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFE
                     EANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAM
                     ADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRA
                     LSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFDFPDI
                     EGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ"
     CDS             19051..19950
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_710"
                     /sec_met_domain="PTA_PTB (E-value: 1.5e-49, bitscore:
                     166.0, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDLIGKASIHKNKTIAVAHAEDEEVIRAVKLAAEHLSARFLL
                     TGDSTKLNELTSFMQGHQVEIVHADTPEESAKLAVRAVHHKTADVLMKGNVPTSVLLKA
                     VLNRQEGLRSASVLSHVAVFDIPDFDRLMFVTDSAMNIAPSLEELRQILQNAVHVAHAV
                     GNNMPKAAALAAVETVNPKMEATVNAAALAQMYKRGQIKGCIVDGPLALDNAVSQIAAA
                     QKKISGDVAGNADILLVPTIEAGNILYKSLIYFAKASVAAVITGAKAPIALTSRADSAE
                     NKLYSIALAICASEEYTH"
     CDS             19962..21056
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ELFV_dehydrog_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_711"
                     /sec_met_domain="ELFV_dehydrog (E-value: 2e-10, bitscore:
                     37.7, seeds: 97, tool: rule-based-clusters)"
                     /sec_met_domain="ELFV_dehydrog_N (E-value: 2.3e-29,
                     bitscore: 98.9, seeds: 410, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRM
                     WTYENEEAAIEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRYIQ
                     GLNGRYITAEDVGTTVEDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAK
                     AAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGARAVD
                     PDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEMGIVYA
                     PDYVINAGGVINVADELYGYNAERALKKVEGIYGNIERVLEISQRDGIPAYLAADRLAE
                     ERIERMRRSRSQFLQNGHSVLSRR"
     CDS             21081..22166
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Butyrate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_712"
                     /sec_met_domain="Butyrate_kinase (E-value: 1.5e-153,
                     bitscore: 507.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLHDEKRILTINPGSTSTKIGVFHNERSIFEKTLRHNIEELQRFD
                     RIIDQYEFRKNHILETLHEQGINISKFDAVCARGGLLRPIEGGTYVVNDEMIEDLKSGY
                     AGQHASNLGGIIAREIADGLNIPSYIVDPVVVDEMSVLAKVSGMPEIERKSIFHALNQK
                     AVARKAAASLGKRYENMKMIITHMGGGITIGVHDRGRVVDVNNGLHGEGPFSPERAGTV
                     PAGDLVDLCFSGEYTKEEIMKKLVGTGGLLGYLGTNDAVKVEQMIQGGDEKARFIYDAM
                     AYQVAKEIGAASAALKGEVEAIVLTGGLAYGKSFVSAIRSYIDWISDVLVYPGENELQS
                     LAQGALRVLQGEEQSKQYRIE"
ORIGIN
        1 atgacgtcaa agaaagaacg attagatgta ttattagtgg aaagagggct ggcggaaacg
       61 cgtgaaaaag ccaaaagagc cattatggcg gggatcgtct actcaaacga aaaccgcttg
      121 gacaagcctg gtgaaaaaat tgaccgcgac cttccgttaa ccgtcaaagg aaacccgctg
      181 aggtatgtga gcaggggcgg cttaaagctc gaaaaagcgt tgaaagagtt tcccgtctct
      241 gtcaaagata aaattatgat tgatattggc tcctccaccg gcggttttac ggactgcgct
      301 ttgcaaaatg gagctaaaca gtcatacgct gtggatgtag gctataatca gcttgcatgg
      361 aagcttagac aggatgaacg ggtcgtcgtg atggaacgga cgaactttcg ttatgcaaca
      421 ccggcagact ttacaaaggg catgccggag tttgccacaa ttgatgtgtc ctttatttca
      481 ctgcggctca tcctgcctgt cctaaggact ttgcttgtac cgggcagcga ctgcatggct
      541 ctagttaagc ctcagtttga agcgggacgg gaatccgtcg gcaaaaaagg gattgttaga
      601 gatcctaaag tgcatgctga tgtgctcaag cgaatgatca gtttttctgc cgctgaaggc
      661 tatatctgta aaggcttgtc attttctcca atcacgggag gagacggaaa tattgagttt
      721 ctccttcatt tgcattggcc gggagaggga caggaaggcc aggagctgcc ggaagaagag
      781 atcatgcgcg ttgtagaaga agcacataag acgttaaaag aaaaaaaagc agatgtaccg
      841 gaataatagg gcgctattat tccttttttc tgcattcatg tacaatgtgc agagaatcat
      901 ataacataaa agaacagata agcttggaaa tagaggtgct tacatgaaca aaggccagag
      961 gcatattaaa atcagagaga tcattacaag caatgaaatc gaaacgcagg atgaattggt
     1021 cgacatgcta aagcaggatg gatacaaagt aacgcaggcc acggtatcac gggatattaa
     1081 agaacttcac cttgtgaaag tgcctacgaa taatggttct tacaaataca gtcttccggc
     1141 ggaccagcgt ttcaatccgc tgtcaaagct aaagcgggca ttgatggacg catttgtgaa
     1201 aatagactca gcaagccata tgattgtgct gaaaacgatg ccgggcaatg cccaggcaat
     1261 cggggcgctg atggacaatt tggactggga tgaaatgatg gggaccattt gcggagatga
     1321 tacgatttta attatttgcc ggactcctga agatacagaa ggcgtaaaaa acaggctcct
     1381 tgaactgctg taacagaaaa tctaacaaag ataagaggtg taatgctgtt tgttagctga
     1441 actatcgatt aaaaactttg ccattattga ggaactgacg gtttcttttg aacgcgggct
     1501 tacggtttta acaggagaaa ccggagccgg caaatccatc atcatagatg ccatttctct
     1561 tttagtcgga ggccgcggat catctgaatt tgttagatat ggggaagcaa aagccgaact
     1621 tgaagggctg tttctgttgg agagcggcca tcctgtttta ggcgtatgcg ctgagcaggg
     1681 aatcgacgtt tcagacgaaa tgatcgtcat gagaagggat atcagcacga gcgggaaaag
     1741 cgtttgccgt gtcaatggca agcttgtcac gattgcttcg ctaagagaga tcggcaggct
     1801 tttattagat attcacgggc agcacgataa ccagctgtta atggaagacg aaaatcatct
     1861 ccagcttttg gacaagtttg ccggggccga agtggaaagc gcgcttaaaa cgtatcagga
     1921 agggtaccag cggtatatga agctgctcaa aaagcttaag cagctttctg aaagcgaaca
     1981 ggaaatggcc catcgtcttg atcttattca atttcagctc gaagaaatcg aatcggcaaa
     2041 gcttgagctt aacgaagatg aacagctcca agaagagcgc cagcaaattt caaactttga
     2101 gaagatatat gagtcgctgc aaaatgcata taacgcgctt cgcagtgagc agggcggatt
     2161 ggactgggtt ggaatggcat cagcgcagct tgaagatata tctgatataa acgaaccgct
     2221 gaaaaaaatg tctgaaagtg tttcgaactc ctactatttg cttgaggatg ccacatttca
     2281 gatgagaaat atgctggatg agcttgaatt tgatccggaa cgcctgaact atattgagac
     2341 gcgacttaat gaaatcaaac agctgaaacg aaaatacggt gccactgttg aagacatttt
     2401 ggaatatgct tctaaaattg aagaagagat tgaccaaatt gaaaacaggg acagccatct
     2461 tcaaagcttg aaaaaggagc ttgactccgt cggcaaagat gtcgcagtgg aagcggaaaa
     2521 tgtgtcacaa atccgaaaaa catgggcgaa aaagctggct gatgagattc atcgggaatt
     2581 aaaaagcctg tacatggaaa aatcaacttt tgatacggaa tttaaggtca gaacagcgtc
     2641 acgcaatgaa gaggcgccgc ttgtaaacgg ccagcccgtt cagctgactg aacaagggat
     2701 tgacctggtg aagtttttaa tttcaaccaa tacaggcgag ccgctgaaat ccctttcgaa
     2761 agtcgcttca ggtggagagc tgtcacgggt gatgcttgcc ataaaaagca ttttttcctc
     2821 acaacaggat gtgacatcga tcatttttga tgaggttgat accggtgtaa gcggcagggt
     2881 cgcacaggca atcgctgaga agatccataa ggtgtcaata ggttcacaag tgctgtgcat
     2941 tacacacctg cctcaggtgg ctgccatggc cgatacgcat ctttatattg cgaaggagtt
     3001 aaaagacggc agaacgacga cacgtgttaa gccgctctct aagcaggaaa aggtagcgga
     3061 aatcgggcgc atgattgcag gtgtcgaggt aaccgattta acgaaacgcc atgcgaaaga
     3121 acttttaaaa caagcggatc aagtcaaaac aactgggtaa gctgcgcgaa aagcgcagct
     3181 tatttttttg tttacatcca ttcgttcatc agtatatcca atgtttttct tcatatgaca
     3241 gttataaata agccgtcaga aggcaaaatt aaatgatgta gcagcaagtc ataaagaagg
     3301 tgtgggatag gagcgaggag agtgaagtag tgaatgcccg ataacatcag aaaagcagta
     3361 ggtttaattc tccttgtttc gttattaagt gtaggtttat gcaaaccgct aaaagaatat
     3421 ttactgattc caacgcaaat gagagtattt gaaacccaaa cacaagcgat tgaaacgagt
     3481 ttatcggtaa acgctcagac atcagaatcc tcagaagcgt ttacagtaaa gaaagatccg
     3541 catgaaatca aggtgacggg caaaaaatca ggtgagtcag aattagtata tgatcttgcc
     3601 ggatttccaa ttaaaaaaac aaaagtgcat gttcttcctg atttaaaggt tatacctggc
     3661 ggacaatcaa tcggtgtaaa acttcattcc gtcggtgttc ttgtcgtcgg atttcatcaa
     3721 atcaatacaa gtgaaggcaa aaaatctccg ggagaaacgg ccggaattga agcgggcgac
     3781 atcattattg agatgaatgg acagaaaatt gaaaaaatga atgatgtagc cccatttatt
     3841 caaaaggctg ggaaaactgg tgaatcttta gatttactga tcaaacgtga taaacagaaa
     3901 atcaaaacga agctgatccc agaaaaggat gaaggagaag gcaaatacag aatcgggtta
     3961 tatatcagag attctgctgc cggcatcggc actatgacct tttatgaacc gaaaacaaaa
     4021 aaatacggag cacttggcca cgtgatttcc gatatggata caaagaaacc aattgtagtg
     4081 gagaatggag aaattgttaa atccactgta acatcaattg aaaaagggac aggcggtaat
     4141 ccgggagaaa aactggcgcg attttcctca gaacgcaaaa cgatcgggga tattaacaga
     4201 aacagcccat ttggaatttt tggcacgctg catcagccga ttcaaaacaa catatcagat
     4261 caagcattgc cggttgcgtt ttctaccgaa gtcaaaaaag ggccggctga aattttaacg
     4321 gttattgatg atgacaaagt agaaaaattc gatattgaaa tcgtcagcac aacgccgcaa
     4381 aaattccctg cgacaaaagg aatggtgttg aaaattaccg atccaaggct gttgaaagaa
     4441 acaggaggca tcgtccaggg gatgagcgga agcccgatta ttcaaaatgg aaaagtgatc
     4501 ggtgctgtca cccatgtatt cgtaaatgac ccgacaagcg gctacggtgt tcatattgaa
     4561 tggatgctgt cagaagcagg aatcgatatt tatggaaaag aaaaagcaag ctgactgccg
     4621 gagtttccgg cagttttttt attttgatcc ctcttcactt ctcagaatac atacggtaaa
     4681 atatacaaaa gaagattttt cgacaaattc acgtttcctt gtttgtcaaa tttcattttt
     4741 agtcgaaaaa cagagaaaaa catagaataa caaagatatg ccactaatat tggtgattat
     4801 gattttttta gagggtatat agcggttttg tcgaatgtaa acatgtagca agggtgaatc
     4861 ctgttaacta catttgggga ggaagaaacg tggagaaaat taaagtttgt gttgctgatg
     4921 ataatcgaga gctggtaagc ctgttaagtg aatatataga aggacaggaa gacatggaag
     4981 tgatcggcgt tgcttataac ggacaggaat gcctgtcgct gtttaaagaa aaagatcccg
     5041 atgtgctcgt attagatatt attatgccgc atttagacgg acttgcggtt ttagagaggc
     5101 tgagggaatc agatctgaaa aaacagccga atgtcattat gctgacagcc tttgggcagg
     5161 aagatgtcac gaaaaaggcc gtcgatttag gcgcgtccta ctttattctc aaaccgtttg
     5221 atatggaaaa ccttgtcggc catatccgcc aggtcagcgg aaatgccagc agtgtgacgc
     5281 atcgtgcgcc atcatcgcaa agcagtatta tacgcagcag ccagcctgaa ccaaagaaga
     5341 aaaatctcga cgcgagcatc acaagcatta tccatgaaat cggcgtccca gcccatatta
     5401 aaggctatct ctatctgcgc gaagcaatct caatggtata caatgacatc gaattgctcg
     5461 gcagcattac aaaagtcctc tatccggaca tcgccaaaaa atttaacaca accgcaagcc
     5521 gtgtagaaag agcgatccgc catgcaattg aagtggcatg gagcagagga aacattgatt
     5581 ccatttcctc gttgttcggt tatactgtca gcatgacaaa agctaaaccg acaaattcgg
     5641 aattcattgc aatggttgcg gataagctga gattagaaca taaagcttct taaacatgag
     5701 cttattaagt ggtcattaaa ccaaacgtct tttatttatt agtttgcgct gataaatagg
     5761 aggcgttttg ttttggggac atttgtagta tgggagaaga atattaagta tccgcatata
     5821 gtaaaggata ggtttgaaaa gtaaggaaag caaatggcgg tattacctgc actcttggtc
     5881 cattcataca tcttatagga tcacgaagca tgatcgaccc tagatgtttc cgttataaaa
     5941 tgaaaccttt ctcctgcaaa atcgtaagta aggcgtattc atgtaaaaag gagacgtacg
     6001 aatgaaaaag aaaaaagcaa gaaagcgtga ggggtttttc ctggattttc ttttcgaagt
     6061 tggcggggag ctctttcttt tgctgtttag atgtgtacac aaactattta tataaaggga
     6121 aaaaagactg ccgaatcgtt tcggcagtct ttgcacatta atctttataa ggcacccagc
     6181 ctggcgtgtt cacaattgct tgccatagcg gttcaggcaa atgatatttt tctttatctg
     6241 tgcctttgat cactgtttcg atttgctttt cacggccttc ttttactttt accgtccagt
     6301 cagggtcaac tagaatttcg cgtcccatag cgaccagcgg aataccgttt tcgatgacgg
     6361 caagcgcgtc atcagcggaa tggatggaac cgacggcgat cagcggcact ttgtttccga
     6421 cacgttcatt caataagtcc atgcgtgtgc gagtcggatc tgcaccgcgg cgcgcttttg
     6481 agttcacgtc catcagtgag atatgaagat aatccaattc tttatcccct aaagcatcaa
     6541 caagcgtata agtttcagtc attgtcaatc ccggtgtctc aggttcttcc ggagacaggc
     6601 ggtatccgac taagaacgca cccttcgcat gttctgaagc ggcttttttc acttcatcga
     6661 caatagcgag cgggaaggct aatcgttttt catcgcttcc tccccagcga tccgtgcgct
     6721 ggttggtttt cggagaataa aactgctgaa ttaagtagcc gtttgcaccg tgaatttcga
     6781 caccgtcaaa gccggcttca atggcgcgtc ttgtcgcttc tccaaacgcc ttcacaatgt
     6841 tttccacttc ttcttctttt aatgcgcgag caatttgttt gccgttatca aacacgtcac
     6901 ttggccccac aacatcctgt tgaggaacga gctcagacgg gcactcaata ccgccgtgat
     6961 gaatttgtac aacagcttta gcgccttgtg cctgaatggc ttgtgttaac ttttttaaac
     7021 ctggaatgtt ggaatcgtca tggatggccg gctgcccggg gaatgctttt ccgtccggtg
     7081 taacatttgc gcaggctgta atcaccattc ccatctcttt tgaacggggg atgatgtagt
     7141 cgagctccgc ttcagatatt gtaccgtctt cattagaagc gtaatgagtc atcggtgcta
     7201 ctgcgatccg gttgttgatt gtaacgccgc ttttaaacgt aaatggttca aaaagtggct
     7261 tatacttagg attcatttga tcatcttctt tcgtttggat tcgcacatat tctagcctat
     7321 atgtaaaaat taatgcaatt gatctgcttt accgactgaa tatcttgagt gcagagtgat
     7381 gttttcgccg ctctttttcg gggcctttgt agccgccgct gatttggtgg ccgatggagc
     7441 atgtgatgac agctgccgcc agcagcagaa cgaatttttt catggcttta acttctttca
     7501 ataaagtaaa tatcctttaa aaggttacgc ttggctgacc cacccgtcaa acgatttgct
     7561 caccctattc tcaaattttt taaaatgaat aaaaagttgc ttctttccgc taattttttc
     7621 taattggcgc ctcaattaga gccatcctca tagacaaatc tgctcgttat ctttctaaca
     7681 acaggaaatg atcgggtcgt atagcccttt tgaaaatcat ggaacttgct cgcctgcatt
     7741 cgcgttgtct ttacaaattc gccattctgg tcaaagataa aagccaaaca tcaggaagag
     7801 gtggtcatgt gaaacaaacg gttcttttgc tgtttactgc gctctttctt tcggggtgca
     7861 gtgttgcaag tgcggatgac tcagtgccaa ggtttaccga agagggaaaa tacattggct
     7921 cggctgatcc tcatacgatt gcggtttctc ttaatggaga agaaaccatg atacaagttc
     7981 cgaaggataa acgtgatgaa tgtgaatcac tgccagatca gacacatgtc ctggtgaaat
     8041 atacaaagaa ggataatgga actttacagc tggaagatat tcagctgcga aagaactcgt
     8101 gaccggaggg agtaagttga gaatgttatg gaggagcttg gcgctgtgcg gattggcttt
     8161 gacgctcgcg ccttgtgcac aggcagcaga gccgatagaa gggaaaacag tgtatattga
     8221 tgccggacac ggcggtgaag atagtggagc ggtcggaaac gggctctttg aaaaggatat
     8281 taatttgtct gtctcagagc atgtgacaga caaactaaaa gaggagggag ccaatcctgt
     8341 tgcatcccgg tctgacgatc attttctgac cttggaggaa agagtggcta aggcaagtgc
     8401 caatcaggct gacctttttg tcagcattca tgtgaattca ggggttgctt cagcttcagg
     8461 aacagaaacg tattttcaat ctgattatga aggggagagc agccggcgtc tcgcatccga
     8521 tattcagtca gagctcgttt cttccttaca aacgagagac aggggcgtga aagaatcaga
     8581 cttttacgtc attacatatt cacaaatgcc aagtgtgttg gcggagcttg ggtttatcac
     8641 taacagctct gacgcggaca agctgggaag tgaagaatac cagcaaaagg ccgcagatgc
     8701 gattgtcaac ggcattgatt cttattatga tcagtagatt gatacagcct taatcctaga
     8761 gtggaaccga caaaataagt ataatggaga aaactttagg gtttgaggtg aaacgatgac
     8821 aaagattttt gcccaccggg gggcatcagg tcaatttccc gaaaatacaa tgcttgcatt
     8881 tgaaaaagga attgaagccg gagcggatgg gatagagctt gatgtacagc tgacgaaaga
     8941 cggacgcatt gttgtaattc atgatgaaag acttaatcgc acgacatcac ttaaaggatt
     9001 cgtgaaggat acagcctatg atgaggtaaa gactgcgaat gcggccgctg gtcacgatca
     9061 agcgtacagc gatataaaag tgccgctgct agaagatgtg ctctcgtggg cggtaaaaaa
     9121 ggattttctc atcaacattg aattaaaaaa cagcgtgatc cgctatgagg gaatggaaga
     9181 aaaagtgctg gaggcagtga agcgatttaa tgtagaggac agagtcatcc tatccacgtt
     9241 taatcatgac agcttggcgc tgtgcgcccg gcttgcaccg catatcgaac gggcagtatt
     9301 aacttcagat gtgctttatc aggcagatcg atatatcgcg tctattccgg cttccggcta
     9361 tcacccgaag ttaaacagcc caggggtcac agatgaagta ctgaagaaaa tgaggaacgg
     9421 tttgattaag gtaaggccgt atacagtcaa tcgtccggaa gatatgaagc gtctcattga
     9481 agcgggagca gacggcatgt ttaccgactt tccagaaaag gcttcggcat tgctgaaaaa
     9541 tgaatagttg ttagaaggag gctgtttgac gcagccttct tttttcattc attcatgccc
     9601 gtttcaaagc atacattcat agaagacaac tagaaattgt aagcgctgtc tatcttctga
     9661 atgaggtgaa accatgagga aaacagtcat tgtaagtgct gcaagaacgc catttggcaa
     9721 attcggcgga gtattgaaag aggtgaaagc tgctgagctt gggggcattg tgatgaagga
     9781 ggcgctgcaa cgggctggag tctctggaga tgatgtagaa ggaaacgtca tgggcatggt
     9841 tgtccaggcc ggctcagggc agataccttc ccgtcaagct gcccgtctgg cgggaatgcc
     9901 ttggagtgtg ccgtcagaaa cactgaataa agtctgtgct tccggccttc gcgctgtcac
     9961 tttatgtgat caaatgattc gggcgcagga tgcggacata cttgttgcgg gggggatgga
    10021 aagcatgagc aatattccgt atgccgttcc cgccgggcgc tggggagcac ggatggggga
    10081 cggcgagctt agggacttaa tggtgtatga cggattaacg tgcgcatttg acgaggtgca
    10141 catggctgtt cacggaaata cagctgccaa ggaatatgca atctcacgaa gagagcagga
    10201 cgaatgggcg ttgagaagtc atgcaagggc agctaaggcc gccgatgaag ggaagtttca
    10261 ggatgaaatt gttcccgtca actggatcgg ccgaaaagga aaaccaaacg ttgttgataa
    10321 agatgaagcg attcgccgtg acacaagtct ggatcagctc gcgaaacttg ctccgattta
    10381 tgcaagtgac ggttctatca cagccggcaa tgctcccggg gtcaatgacg gagccggcgc
    10441 gttcgtgctg atgtctgagg aaaaagctgc tgagcttggc aaacggcctc tggctacaat
    10501 tcttggtttt tcaactacgg gaatgccagc gcacgagctg gcggcagcgc cggggtttgc
    10561 cattaacaag ctcctgaaaa agaacggttt gactgtccaa gatattgact tgtttgaagt
    10621 aaatgaagct tttgcttcag ttgttttgac atgtgaaaaa atcgtaggtt tcgatcttga
    10681 aaaagtaaat gtgaatggcg gtgcgatcgc gctcggccac ccgatcggcg cgagcggtgc
    10741 gagaattctc atgacgcttg tttatgaatt aaagcgacgg ggagggggtc tgggcgttgc
    10801 cgctatttgc agcggggcag cacagggaga cgccgtctta gtgcaggttc attaaaacat
    10861 gatgaaaaag gggatttgaa tggaaatcaa acaaatcatg gtagctggcg caggtcagat
    10921 ggggagcgga attgctcaaa cagccgccga cgcgggcttt tatgtgcgga tgtatgatgt
    10981 gaatccagag gccgcggagg caggattgaa acggctgaag aaacagctgg cccgtgatgc
    11041 tgagaaagga aaaaggaccg agacggaagt gaagagcgta atcaaccgca tttcgatttc
    11101 tcaaacgctt gaggaggcag agcatgcgga cattgtgatt gaggctatcg cagaaaacat
    11161 ggcggcaaaa actgagatgt ttaaaacact tgatcgcatg tgcccgcctc atacgatttt
    11221 ggccagcaat acatcttcct tgcctattac agaaatcgct gctgtaacaa accggcctca
    11281 acgggttatt ggcatgcatt ttatgaatcc cgtccctgta atgaagctgg tagaagtgat
    11341 tcgaggcttg gctacatcag aagaaacggc cttagatgtt atggcattag cggaaaagat
    11401 ggggaaaaca gcggtagaag tcaatgattt tcctgggttt gtttccaacc gtgtgcttct
    11461 tccaatgatt aatgaagcca tctattgcgt gtatgaggga gtggcgaagc cggaggcaat
    11521 agatgaagtg atgaagctgg gcatgaatca tccgatgggt ccgcttgcat tagcggattt
    11581 tatcggactg gatacgtgtt tatcaattat ggaagtcctt cactcaggcc ttggcgattc
    11641 caaataccgt ccttgcccgc tgctccgcaa gtatgtcaaa gcaggctggc ttggcaaaaa
    11701 gagcggacgc ggtttttatg actatgagga gaagacttcc tgaagtctat tccatccggg
    11761 ggtggccgag ttgcatgtaa cccaagagca agtcatgatg cgaaaaatgg tgcgtgattt
    11821 tgcacgaaaa gaaattgctc ccgctgcgga aatcatggag aaaacggacg aatttccctt
    11881 tcagctgatc aaaaaaatgg gtaaacacgg actgatggga ataccggtgc cggaacaata
    11941 cggcggtgct ggagcggacg ttgtttctta tattttggca attcatgaga tttctagaat
    12001 cagcgcggct gtcggcgtga ttctctccgt tcatacctca gtcggcacga atccgattct
    12061 gtatttcggc aacgaagaac agaagatgaa atatatacca aagctcgcgt caggagacca
    12121 tttgggcgca tttgcactaa cggagcctca ctcggggtcg gatgccggga gcctccgcac
    12181 aacagcaatc aaaaagaacg gcaaatacct attaaacgga tcgaaaatat tcataacgaa
    12241 tggcggagca gctgatatct atatcacatt tgctttaaca gctccagatc aaggcaggca
    12301 cgggatttcg gcttttattg ttgaaaaaaa cacacccggt tttaccgttg gaaaaaaaga
    12361 aagaaagctg gggctttatg gctccaatac tacggaactg atttttgata atgcagaagt
    12421 gcctgaagcc aatttgcttg gcaaagaggg ggatggcttt cacattgcca tggcgaattt
    12481 aaatgtcggc cggatcggca ttgcggcaca ggccctcgga attgcagagg cggctcttga
    12541 gcatgccgtt gattatgcga agcagcgagt gcaatttgga aggccgattg cagccaatca
    12601 aggcatatca tttaagctgg ctgatatggc gactagagct gaggcggcaa gacatcttgt
    12661 ctaccacgct gcagaccttc ataaccgcgg cctaaactgt ggaaaagaag cgtctatggc
    12721 taaacaattt gcttccgatg cagccgtaaa ggcggcgtta gacgccgttc aaatttatgg
    12781 gggatatggc tatatgaagg attatccagt tgagcgcctg cttcgcgatg caaaggtgac
    12841 gcaaatttat gaagggacga acgagattca aagactgatt atttccaagt atttgcttgg
    12901 cggaacctga tagacaaaaa acgcaaaaac ggaggttgag gatatggagg agaaacagca
    12961 ttattctcca gggttggacg gtgtgattgc ggcagaaact catatttctt atcttgacac
    13021 gcagtccagc cagattttga taagaggcta tgatttaata gaactttctg aaacaaaaag
    13081 ctatctggag cttgtccatt tattgctgga gggcaggctg ccagaagaaa gtgaaatgga
    13141 aacgctggaa cgtaaaataa acagtgcctc aagcctgcct gctgatcatc tccgtctgct
    13201 tgagctgctc cctgaggaca ctcatccaat ggatggtctg cgtaccggcc tgtcggcact
    13261 tgctggctat gatcggcaaa ttgatgatcg gtctccttcc gcaaacaaag aacgcgccta
    13321 tcagcttctt gggaaaatgc ctgccctcac tgctgccagc tacaggatca ttaataagaa
    13381 agaaccgatt cttccgcttc aaaccctatc ctacagtgcg aattttctct acatgatgac
    13441 agggaaattg ccgtcttcat tggaagaaca gatttttgac cggtcgctcg tcctgtacag
    13501 tgagcatgag atgccgaatt caacctttgc ggccagggtc attgcatcta cacattcaga
    13561 tctttatggg gctttgactg gggctgtcgc ttccctgaaa gggaatcttc acggaggagc
    13621 aaacgaagct gtgatgtatt tgcttttgga ggcaaaaacg acatctgatt ttgagcagct
    13681 tttgcaaaca aaactgaaaa gaaaagaaaa aatcatgggc ttcggccacc gggtgtatat
    13741 gaaaaaaatg gacccgagag cactcatgat gaaagaggcg ctgcagcaat tatgcgataa
    13801 agccggtgac catcgtttat atgagatgtg cgaagcgggt gagcggctga tggagaagga
    13861 aaaagggctt tacccgaatt tggattacta tgctgcccca gtgtattgga tgctcggcat
    13921 accgattcct ttatatacgc cgatcttttt cagcgcgaga acgtccggtt tatgcgccca
    13981 tgtgatcgaa cagcatgcca ataatcggct cttccgtccc cgtgtcagtt acatgggccc
    14041 gcgatatcaa acaaaatcat gaaaggagct ggtagaatgc cgaaaacgga tcgtgttatc
    14101 gaagaaatca cagactatgt gcttgagaaa gagattacta gtgccgaagc gtatacaaca
    14161 gcggggcatg tattgctgga taccctgggc tgcggaatct tggcgctacg gtatccggaa
    14221 tgcacaaagc tgcttggccc gattgttcca ggaacgactg tgccgaatgg aagcaaagtg
    14281 ccgggaacgt catatgttct cgatcctgtg agggcagcgt ttaatattgg ctgcatgatt
    14341 cgctggctcg attacaacga tacgtggctg gcggcggagt gggggcatcc atccgataac
    14401 ttgggaggaa tccttgccgc tgctgattat gtatcaagag tgaggctgtc tgaaggaaaa
    14461 gagccgttaa cggtacgcga cgtacttgag atgatgatca aagcacacga gatccaaggt
    14521 gtgctggcgt tagaaaacag cttaaatcga gttggccttg accatgtgct gtttgtcaaa
    14581 gttgcgacaa ctgctgttgc agcaaagctt ttgggcggcg gaagagaaga aatcaaaaat
    14641 gcgctttcga atgcatggat tgacaatgca gcattgagga cataccgcca ttcaccgaat
    14701 acaggctcgc gtaaatcatg ggcggcagga gatgcaacga gcagaggtgt tcatttggcg
    14761 ctgatgtcgt taaaagggga aatgggttat ccgacagcct tgagtgcacc gggttggggg
    14821 ttccaagacg ttttattcaa taagaaagag atcaagcttg cccgtccgct cgacgcttat
    14881 gtcatggaaa atgtgttatt taaagtgtct tatcctgcgg aatttcacgc ccagacagcg
    14941 gcggagtccg ccgtcattct tcacccgcag gtaaagaacc ggattgacga gattgaccga
    15001 gttgtcatca gaacgcatga atcagctatc cgaatcattg ataaaaaagg cccgctccac
    15061 aatccggcag accgtgatca ctgcctccaa tacattacag caatcggttt gctttttggt
    15121 gatatcaccg cacagcatta tgaagctgaa acagcgagtg atccgaggat agataaactt
    15181 cgtgataaaa tggaagtgac tgaaaataaa acatataccg aggattattt aaaacctgat
    15241 aaacgttcca tctcaaatgc cgttcaggtt cattttaaag acggaacgag cacggaaatg
    15301 gtggaatgtg agtttcccct cggccatcgt tttcgaagag aggaagcagt gccgaaactg
    15361 ctggaaaagt tttctgacaa tctcaaaacc cattttcctg ataaacagca caaacacatt
    15421 tatgagcgct gtaccagcta tgagacatta caaacgatgc gcgtaaatga attcgtagac
    15481 atgttctgca tgtaaaaggg ggatttgttt catgtcgtgg atcgtcaata agcaatcgtc
    15541 acaagaggag cttgccgggc gtttccgcaa gctgatgtca gcaccggaca ttcttcaaat
    15601 tcccggcgcc catgacggga tggccgcttt gcttgcgaaa gaagccggtt tttctgctat
    15661 ttatttgtcc ggtgctgcct atacagccag cagggggctg cctgatttag ggatcatcac
    15721 atcggcagag atagctgaac gggccaaaga tcttgtgcgt gcagctgatc tgcctctgct
    15781 tgtggatatc gatacgggat ttggcggtgt cttaaatgcc gcccgaacag cccgggagat
    15841 gcttgaagca agggtagcag ccgttcaaat agaagaccag cagctcccaa aaaaatgcgg
    15901 acatttaaat ggcaaacagc tagttccgat aaaggaaatg gcgcaaaaaa taaaagccat
    15961 taaacaagcg gcaccctccc ttattgttgt tgcccgtact gatgccaggg cgcaggaagg
    16021 gcttgctgcc gcaataaaac gttcagaggc ttacattgag gcgggagcgg acgcaatttt
    16081 cccggaagcg ctacaggcgg agaatgaatt ccgccagttt gctgagcgta tccccgttcc
    16141 gctccttgcg aatatgactg aatttgggaa aacgccatat tatcgtgccg atgaattcga
    16201 agatatgggg tttcacatgg tgatatatcc tgtcacctcg cttcgagcgg cggcaaaagc
    16261 ttgtgagcgg atgtttggtt tgatgaagga gcacggctca caaaaagaag gacttcatga
    16321 tatgcagaca cgaaaagaac tgtacgatac gatttcttat tatgactatg aagcgttaga
    16381 caaaacgatt gccaagaccg ttttgcctga cgaataatgc aacaaaaaaa gccggagcat
    16441 tctccggctt tttttcagct atcgttttct gaatcgcggg ctgacttgat tgcgttttct
    16501 gtctctgtat aaaatgaacc cggccagcac atagaggccg atcgcaaaaa agatgaatcc
    16561 tgacaaccct tggagccaaa gagctgaaaa tggcttgatt gtatgaccga aaagtgtatc
    16621 tctcatcagt ttaatgccta aagcagaaat agccccgggg atgactaata ttaaaagcgc
    16681 aagaagtcgg ctcatcttca gaaaacccct ttatcttttc atttccttta ttgtccagcg
    16741 gaaaaaatat tttgtcaaga gaagaaaacg tggtaacata gggttgtgca aattattgca
    16801 acggaataaa taggtatgca aattttttca tacaaagggg tatcgggatg caaaaggtac
    16861 tgatagtagg tgccggcaaa aggggaacgg cgttattaca tattctgatt aaaacagcca
    16921 tcatagatat aattgccgta gttgacaaag actccgaggc gccgggattg aaagaagcag
    16981 aacagtatgg gattgccgtt tcatctgatt ggaaacctta catacaacaa aaaccggata
    17041 tcgtcattca tactaccggc gatcaagccg tgtttgacga gctccttcaa agaaagcatg
    17101 aagataccat tgtcatgccg ggaaaaatgg catacatcgt ttttcagctg atggaagaaa
    17161 agcagcacct gattcaaatg ctaaaagagc aaacctataa atatgacaga atttttaatt
    17221 ccacccatga tggaatgatt tttattgata tcaatgaaga aatcattctc tttaaccata
    17281 tggccgaaaa aatggtcggg aaaaaacgtg aggaagtcat tgggcgccca ataaaagaag
    17341 tgattccgag cactaagatg ccgcggattt taaaaacaag agtgcctgaa tacaaccaga
    17401 agcagctgtt aggcgatcat ttgcaaattg tgaccacaag gctgccgatt attgatgaag
    17461 gcggacgtct gctcggggct ctttgtgtgt ttaaagatat cactgatgcg gtcgagctgg
    17521 cagaggaagt gaccaactta aagcaggtcc gtacgatgct ggaggcgatt attcaatcct
    17581 ccgatgaggc gatttctgtc gttgatgaaa acggcatcgg cctgctaatc aataaagcgt
    17641 atacgaaaat gacggggctt tctgaaaaag aagtcatcgg caagcctgca aacactgata
    17701 tttccgaagg cgaaagcatg catttaaagg tgcttgaaac aagacgtcct gtccgcggtg
    17761 tcagaatgaa ggtcggcccg aatgaaaaag aggtcatcgt taatgtagca ccggtgattg
    17821 tggacgggat tttgaaaggc agcgtcggcg tgattcacga tgtttccgaa attaaaatgc
    17881 tgacagcgga gcttaatcgc gccagacaaa ttattcgcac gcttgaagcg aaatacacgt
    17941 ttgacgacat tatcggcaaa agcgagcaaa tgctggttgc gcttgagcag gcgaagctcg
    18001 gtgcgaaaac accggcaacc atcttgctgc gcggggaatc aggaacagga aaagaactgt
    18061 tcgcccatgc catccataac gaaagtgacc ggaaatacaa taaatttatt cgcgtgaatt
    18121 gtgcagccct ttctgaaaac ctgctcgaat cagaattgtt cggctatgag gatggcgcgt
    18181 tttcaggagc gaagcgcggc ggtaaaaagg gtttatttga ggaagcaaat aacggcagta
    18241 ttttcttaga tgaaatcggt gagctgacac aaaatatgca ggccaaattg ctacgcgtcc
    18301 ttcaagaaaa ggaaatcgtc agagtgggcg gcacgaaagc gatccctgtc aacgtcagag
    18361 tgatcgcggc gacaaatgta aatattgaaa aggcgatggc ggacggaacg ttccgggaag
    18421 acctgtatta ccggatcaac cgctatccga tctccatccc gcctttgcgt cagcggttgg
    18481 aggacattga agcactgagc gtcagactta tccaaaagat caaccgggat tacggcagga
    18541 atgtaaaagg gctctcacag caagccttgc gcgccttatc tgcctaccat tggcctggga
    18601 atgtccggga gcttgaaaat gtccttggac gagccatgat ttttctgaat ccgcatatgg
    18661 aatggattga aaaagatcac ttgcctgtat tcgaacttga gcaaaaagaa aatgacacag
    18721 accagggaac aggttttgat tttccggata ttgaaggcga aaagctgtct gtcgcagtag
    18781 aaaaatttga agcacatttg atccagcaaa cgcttgaaaa gcatcatttt aaccggacaa
    18841 aaacagcaaa agctctcggt gtcagcattc ggaacttata ttacaaaatg gataaatatg
    18901 gccttgcaaa tgaaggcatg caataatttg cagaataaac gcaaacatct gcacgaatgt
    18961 ttcaatatac ctggtatgac agcaccctta agagctggca tggaacttgc ataataaaag
    19021 gcggagtcga aacaagaaag gtggtaacag atgaagctga aagatttaat cggcaaagcg
    19081 tcgatacaca aaaataagac cattgcggtt gctcatgctg aggatgagga agtgatccgg
    19141 gctgtaaagc tggcagccga gcacctatct gcccgtttct tgttaacggg cgacagcaca
    19201 aaactgaacg agctgacatc attcatgcaa gggcatcaag tggaaatcgt ccatgccgat
    19261 actcctgagg aatcggcgaa attagcggtt cgtgctgtgc atcataaaac agcggacgtt
    19321 ttaatgaaag gcaatgtgcc gacttctgtt ttgcttaaag cggtattgaa cagacaggag
    19381 gggcttcggt cagcaagtgt cctttctcac gtggctgtat tcgatatacc ggattttgac
    19441 cggctgatgt ttgtgacaga ttcggcaatg aatattgctc cttcgctgga agagcttcgg
    19501 cagattttgc aaaatgccgt tcatgtggcc catgcagtgg ggaacaatat gccaaaagca
    19561 gctgcccttg cagcggtcga aacggtgaac ccaaaaatgg aagcaaccgt gaatgcagct
    19621 gctctagctc aaatgtacaa aaggggacag atcaaaggct gcattgttga tggaccgctt
    19681 gctttggata acgcagtttc acaaattgcc gcggctcaga aaaaaatttc gggagacgta
    19741 gcgggcaacg cagatatcct tctcgtccca acaattgagg ccggcaatat tttatataaa
    19801 tcactgattt attttgccaa ggccagcgtg gcggctgtca ttacaggagc aaaagcaccg
    19861 attgctttaa caagcagagc ggactctgct gaaaataaac tgtattccat tgcgctggca
    19921 atatgcgcat ctgaagaata cacacattag gaggaacgaa catggaactt tttaaatata
    19981 tggagaaata cgattacgaa caattggtat tctgccagga tgaacaatct ggattaaaag
    20041 cgattatcgc gattcatgat acaacgcttg gtccggcgct tggcggaacg agaatgtgga
    20101 catatgaaaa tgaagaagcg gcaattgaag atgcgctcag attggctaga ggcatgacct
    20161 ataaaaacgc ggcggccggc ttaaaccttg gcggcggaaa aacagtcatt atcggcgatc
    20221 cgcgcaaaga caaaaatgaa gaaatgttcc gcgcgtttgg ccgctatatt caagggctga
    20281 acggcagata catcacggct gaagatgtgg gcacaacggt cgaggatatg gatatcattc
    20341 atgatgagac agactatgtc acagggattt ctcctgcttt cggctcttct ggaaatccgt
    20401 ccccagtcac agcgtacggg gtgtacagag gaatgaaggc agcagctaaa gctgctttcg
    20461 gaaccgactc tcttgaagga aaaaccattg ctgtacaggg tgttgggaac gtagcctata
    20521 acctttgccg ccacctgcat gaagaaggag caaacttaat cgttacggat atcaacaaac
    20581 aatctgtaca gcgtgcagtt gaagattttg gcgcccgtgc ggtagatcct gatgacattt
    20641 attcacaaga ctgcgatatt tatgcgccgt gtgcccttgg tgcgactatt aacgacgata
    20701 ccattaaaca gctgaaggcg aaagtgatcg caggtgcggc taacaaccaa ttaaaagaga
    20761 cacgccatgg tgatcaaatt cacgaaatgg gcatcgttta tgcaccggat tacgtgatta
    20821 acgcgggtgg tgtcatcaac gtggcagatg agctttacgg ctataatgca gaacgtgcat
    20881 tgaaaaaagt tgaaggcatt tacggcaata tcgagcgtgt acttgagatt tctcagcgtg
    20941 acggcattcc tgcatattta gcggctgacc gcttagcaga ggaacggatt gaacgcatgc
    21001 gccgctcaag aagccagttt ttgcaaaacg gccacagtgt attaagcaga cgttaagaaa
    21061 ttgatctgga ggttatgaaa gtgctacatg acgaaaaacg cattctcaca attaatccag
    21121 gctcaacttc aacgaaaatc ggtgtttttc ataacgaaag aagcattttt gaaaaaacat
    21181 tgagacacaa catagaagag ctgcagcgat ttgaccgaat tattgatcag tatgaatttc
    21241 gtaaaaacca tattctcgaa acgcttcatg aacagggaat caatatttca aagtttgatg
    21301 cagtctgcgc aagaggcggc cttctccggc caattgaagg cgggacctac gtagtgaatg
    21361 atgagatgat tgaggatttg aaaagcggct acgccggtca gcatgcttct aatctcggcg
    21421 gcattatcgc gcgggaaatc gctgacggcc tgaatatccc ttcgtatatc gtcgaccctg
    21481 ttgtcgtaga cgaaatgtca gtgcttgcga aagtttcagg catgcctgaa attgaaagga
    21541 aaagcatttt ccatgcgtta aaccaaaaag ctgtcgctcg taaagcggca gcctcccttg
    21601 gcaaacgata tgagaacatg aaaatgatta ttacccatat gggcggaggt attacaattg
    21661 gcgtccatga ccgcgggcga gtggtggatg tcaataacgg cctgcacggc gagggaccat
    21721 tcagtcctga acgagcagga acagtgcctg cgggagatct tgttgatcta tgtttttcag
    21781 gggaatatac aaaagaagaa atcatgaaaa agcttgttgg caccggcgga cttttaggct
    21841 atctcggtac aaatgatgca gtaaaagtgg aacagatgat tcaagggggc gatgaaaaag
    21901 cccgcttcat ttatgatgcc atggcatatc aggtagcaaa ggaaatcggg gcagccagcg
    21961 cggcgttaaa aggcgaagtt gaagcgattg tgctgacggg aggccttgcg tacggaaaaa
    22021 gctttgtttc tgctatcaga tcatacatag attggatttc agacgtttta gtttatccgg
    22081 gtgaaaatga actgcagtct cttgcccaag gggcgctaag agtattgcag ggcgaagagc
    22141 aatccaaaca atatcgtatt gaatag
//
