LOCUS       c00004_gnlPro..        25404 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONCKDIPA_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 20:56:55
            Original ID  :: gnl|Prokka|ONCKDIPA_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 41801
            Orig. end    :: 67205
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25404
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[51801:57205]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15404
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /neighbourhood="10000"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protocluster_number="1"
     cand_cluster    1..25404
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(3, [Amidohydro_1, Amidohydro_3,
                     Arginase, FGase, Urocanase]) and Lyase_aromatic and
                     Urocanase_C)"
                     /kind="single"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..25404
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="histidine2glutamate_hutHGIU_operon"
                     /region_number="1"
                     /rules="(minimum(3, [Amidohydro_1, Amidohydro_3, Arginase,
                     FGase, Urocanase]) and Lyase_aromatic and Urocanase_C)"
                     /tool="gutsmash"
     CDS             851..1243
                     /locus_tag="ctg4_40"
                     /transl_table=11
                     /translation="MLITKRGNWWEVLHSWWLLLTLVPFALTAFLAFFYIGYRAKNNKW
                     LKYGLIYFIILAIAFVLPSTPGVYIVLPLWVISIIHGLKVRAAYLIQLDVFKQNVEARA
                     YEAVRHEAEAKFGRKPAHRIDLTKQR"
     CDS             complement(1295..1660)
                     /locus_tag="ctg4_41"
                     /transl_table=11
                     /translation="MMYQNQYSGNQLQQCRQTAQQLIQQTQQSSQQYKQMLQQEQQNIQ
                     MLQQMLNHEQHAVHTIQQALQGHEMAIQKCQQIVNVCNQLQQDVSGHMPSPMTNTNVSS
                     FPQTQHHTPFQQHSYQQ"
     CDS             1723..1899
                     /locus_tag="ctg4_42"
                     /transl_table=11
                     /translation="MQAGDSNIYLLCTERNTRLGNGLSSFVFRPFFSEAAFCSVKRDIE
                     SVFNRAQALIQAV"
     CDS             complement(1819..2199)
                     /locus_tag="ctg4_43"
                     /transl_table=11
                     /translation="MNPYQYYTPPAYFPQQQEFEVNRVEYEPYQQEAYYAPYQPEDRQP
                     TALERRVAQLERQNAEQTRELTRLSNEDQRQNREITRMSEQVRRLSQAIEIHSRRLNRL
                     NQRLRAVENRLNIPFHATEGGF"
     CDS             2310..2729
                     /locus_tag="ctg4_44"
                     /transl_table=11
                     /translation="MLRNIRIFIMPILVFGCVMMTGCQLKKADDTPFYYGTWDAGLEPG
                     PMDGVRSETVTFTKDRVLTKQVIKGRGEVDMPSDAYKVISQNTDGTIEIEYLGHPHPVK
                     STLKRGKNNTLIWKIYGGTKTMTRIKTGGEDAHAK"
     CDS             2719..3240
                     /locus_tag="ctg4_45"
                     /transl_table=11
                     /translation="MRNKAADRLVLTGVIVHIIQWFSVLWLFFMLLDQFGHFTIYNPNV
                     VNGSMQSFSFFDMMRALLFSGTLRNTLLLFLFAALLIYLWVNALFILLEIVSYIMIRRN
                     SRSLWAYFPAAMGIKLALLDIAAVPFFAAGLILLKQKTENGEQADKRKRRPRIRKQARY
                     MKRRRRNPSV"
     CDS             3310..4122
                     /locus_tag="ctg4_46"
                     /transl_table=11
                     /translation="MYKLIAIDMDGTLLNDHHEVTAEVRGALDAAKAEGVNIVLCTGRP
                     IGGVRRYLEELNLQEEGDFVIAYNGALVQNTYTNGVVAEQSLGFEDLEALHELSLQLDT
                     PMHYFDTANLYTPNRDISEYTVYESYITKVPLHFRTIDEVPKDILIPKIMFIDDPDKLE
                     KTIASIPESFKEKYTMVKSAPFFHEILHPEVSKGNAVKLLAEKLGIEQKDVMAIGDNGN
                     DMSMIQWAGCGVAMANAIPEVRDIANFETKSNNEHGVAHAIQELVLKK"
     CDS             4193..5134
                     /locus_tag="ctg4_47"
                     /transl_table=11
                     /translation="MDREKQQLSIEAAKLYYQSDYSQQQIAERLNLSRPTVSRLLQYAK
                     EKGYVQIRVMDPFEDLDELGAKLEEKYGLLEAHVVFSPSDDYPAITHYLSRYGADYMHK
                     TVKDGDILGVSWGTTMYQIASRMEPKQVKSVEVVQLKGGISHSNVNTYSSETIQLFAEA
                     FQTMPRYLPLPVIFDSADVKQMVERDRHIKRIIEMGRQANIALFTVGTVRDEALLFRLG
                     YFREEEKQLLKARGVGDICSRFFDAEGRICSSSINGRTIGVELSDLKMKERSILVAGGS
                     RKCKAIHGALTGKYANVLITDQHTAKKLVQEL"
     CDS             5225..5893
                     /locus_tag="ctg4_48"
                     /transl_table=11
                     /translation="MSIASQIDHTALKPHTQKADILQLIKEAKEYKFASVCVNPTWVKL
                     AAEELKGTGVDVCTVIGFPLGATTSETKAFETKDAISKGATEVDMVINIGALKDGDDEA
                     VEADIRAVVEAADKKALVKVIIETCLLTDEEKERACRLAVSAGADFVKTSTGFSTGGAT
                     AEDIALMRKTVGPDIGVKASGGIRTKADVDSMIAAGASRIGASAGVSIVSGGDSGSSDY
                     "
     CDS             5986..7167
                     /locus_tag="ctg4_49"
                     /transl_table=11
                     /translation="MKYFIGIIGIIVFLGLAWLASNGKKRIRIRPIAVMLVLQLILGYI
                     LLNTGIGNFLVGGFAKGFNYLLEYASEGINFVFGGLVNAKQTTFFMSVLLPIVFISALI
                     GILQHWKVLPFITKYIGLALSKVNGMGKIESYNAVASAILGQSEVFISLKKQLGYLTEQ
                     RLYTLCASAMSTVSMSIVGSYMMMLKPEYVVTALVLNLFGGFIIASIINPYTVSKDEDL
                     IVVPEEEKQSFFEVLGEYIMDGFRVAVVVAAMLIGFVALIALVNGVFNAVFGITFQALL
                     GYVFAPFAFLTGIPWNEAVSAGSIMATKMVSNEFVAMQTLSSGDFHFSAHTQAVVSVFL
                     VSFANFSSIGIITGAVKGLHEKQGNVVARFGLKLLYGATLVSFLTAAIVGLIH"
     CDS             7195..8496
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_trans_3N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_50"
                     /sec_met_domain="Glycos_trans_3N (E-value: 1.2e-21,
                     bitscore: 72.2, seeds: 1422, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_3 (E-value: 1.4e-52,
                     bitscore: 174.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMVDLIVKKQNGKELTTEEIQFFVKGYTDGSIPDYQASALAMAI
                     YFQDMTDQERADLTMAMVNSGETIDLSAIEGIKVDKHSTGGVGDTTTLVLAPLVAALGV
                     PVAKMSGRGLGHTGGTIDKLEAIEGFHVELSKDEFIKLVNRDKVAVIGQSGNLTPADKK
                     LYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTDEDAVNLAKAMV
                     RIGNNVGRQTMAVISDMSQPLGFAIGNALEVQEAIDTLRGEGPEDLNELVLTLGSQMVV
                     LAKKAETLEEARTKLQEVMKNGKALEKFKEFLSNQGGDASVVDDPSKLPQAAYKIDVPA
                     KEAGVVSEIVADEIGVAAMLLGAGRATKEDEIDLAVGIMLRKKVGDKVEKGEPLVTLYA
                     NRENVDDVTSKVYDNIRISEKAEAPKLIHTLITE"
     CDS             complement(8535..9953)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_51"
                     /sec_met_domain="AA_permease (E-value: 2e-131, bitscore:
                     434.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVDKGGSQLKRTMKSRHLFMISLGGVIGTGLFLSTGYTLSQAGP
                     GGTIAAYLIGGLMMYLVMQCLGELSVAMPVTGSFQTYATTFIGPSTGFMVGIMYWVNWV
                     VTVGSEFTASGILMQRWFPHSSVWMWSAIFAALLFAANAFSVKLFAETEFWFSSVKIVT
                     ILLFIILGGAAMFGLISLHGSAEAPMLSNFTSHGGLFPNGFLAVFIAMISVSFAFSGTE
                     LIGITAGETANPEKDIPRSIRNVAWRTVIFFIGAIFVLSGLISWKEAGVIESPFVAVFS
                     QIGIPYAADIMNFVILTALLSVANSGLYASTRMLWSLANENMISARFKKVTPKGIPLNA
                     LLASMAVSCISLISSIAAPGTVYVVLVAIAGFAGVVVWMSIALSQLLFRKHYVKNGGRL
                     TDLTFRTPLYPLVPIAAMILCFASCVGLAFDPNQRIALFCGVPCMILCYLIRFLRRKQP
                     KQPVRDIHLDKTMP"
     CDS             complement(10001..10951)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Arginase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_52"
                     /sec_met_domain="Arginase (E-value: 2.8e-64, bitscore:
                     213.1, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDKYPFLQKAGSLFNDRHVTRIGDVTEAWAGQPLKGPALIGAPLS
                     KSSISHSGACFAPGAIRKALGGISAYSAELREHVIDHLYDAGDIQIHVTDIVKSHEHIY
                     QTIHGILADQPDWVPVILGGDNSISYSTIKAIAETKGTAAVFQFDAHHDVRNTEDGGPT
                     NGTPFRRLLDDNIISGQNLIQLGIREFSNSLAYEEYVKDRQAEVHTMEMIREKGLLRTI
                     QDALPAVQKRADSIFISVDMDVLDQAHAPGCPAIGPGGLYTEELLQAVRFLAQEADISG
                     IEIVEVDPTLDFRDMTSRAAAHVILHALKGFKQSR"
     CDS             complement(10944..12209)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Amidohydro_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_53"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.1e-21, bitscore:
                     72.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQIDTILTNIGQLLTMESGGPRAGGSMQDLQVTEDAVIGIHDG
                     HIVFAGHKGAEEGYEARDMIDCGGRLVTPGLVDPHTHLVFGGSREKELNLKIQGISYLD
                     ILAQGGGILSTVIDTKAASEEELIEKGLFHLGRMLSYGITTAEVKSGYGLDKDTELKQL
                     TAAKKLGERQPVDLVTTFMGAHAIPPEYRNSPDEFLDRMLQLLPEIKEKGLAQFADIFT
                     ETGVFTVSQSRDYLQKAAEAGFGLKIHADEIDPLGGAELAAELDAVSADHLVGASDEGI
                     RKLAESGTIAVLLPGTTFYLGKHTYARAREMIDAGVRVSLATDFNPGSSPTENLQLIMS
                     IAALHLKMTAEEIWHAVTVNAAYAIGKGEEAGQIKAGRLADIVIWEAPNYMYIPYHYGV
                     NHVHRVIKNGKTVISREGAALG"
     CDS             complement(12211..13875)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Urocanase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_54"
                     /sec_met_domain="Urocanase (E-value: 8.4e-91, bitscore:
                     299.1, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 1.1e-96, bitscore:
                     317.8, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 3.6e-62, bitscore:
                     203.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEVKKSIRASRGTELECLGWEQEAVLRMLRNNLDPEVAEKPEDL
                     IVYGGIGKAARNWDAFHAIERSLKTLKDDETLLIQSGKPVGLFRTHSRAPRVLLANSVL
                     VPKWADWEHFHDLEKKGLMMYGQMTAGSWIYIGSQGILQGTYETFAELARQHFGGSLKG
                     TVTLTAGLGGMGGAQPLSVTMNDGVVIAVEADEKRIDKRIETNYCDRKTASIDEALRWA
                     ESAKQAGKPLSIGLLGNAAEVHHELLSRGVHIDIVTDQTSAHDPLIGYIPAGYSLEEAD
                     RLRREQPELYVRLSKQSMKKHVEAMLAFKKKGAIVFDYGNNIRQAAKDEGLADAFDFPG
                     FVPAYIRPLFCEGKGPFRWAALSGDPEDIYRTDALLKELFPENKALHRWIDMAQKKVTF
                     QGLPSRICWLGYGEREKMGLAINELVRNGELKAPIVIGRDHLDCGSVASPNRETEAMKD
                     GSDAVGDWAVLNALVNTASGASWVSFHHGGGVGMGYSLHAGMVAVADGTRLAEERLARV
                     LTSDPGMGIIRHADAGYEKAAQVAEEQDIMIPMKKER"
     CDS             complement(13872..15404)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     histidine2glutamate_hutHGIU_operon: Lyase_aromatic"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_55"
                     /sec_met_domain="Lyase_aromatic (E-value: 4e-194, bitscore:
                     641.4, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTLDGSSLTTADAQRVLFDFEEAQASAESMERVKKSRAAVERIV
                     QEEKTIYGITTGFGKFSDVLIQKEDAADLQLNLILSHACGVGDPFPESVSRAMLLLRAN
                     ALLKGFSGVRTELIDQLLAYLNHRIHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFY
                     EGDQMPTAHALEKANLQPVVLTSKEGLALINGTQAMTAMGLIAYLEAEKLAYQSERIAS
                     LTIEGLQGIMDAFDEDIHAARGYQEQMDVAERIRYYLSDSKLTTVQGELRVQDAYSIRC
                     IPQVHGASWQTLAYVKEKLEIEMNAATDNPLIFEDGAKIISGGNFHGQPIAFAMDFLKV
                     AAAELANISERRIERLVNPQLNDLPPFLSPQPGLQSGAMIMQYAAASLVSENKTLAHPA
                     SVDSIPSSANQEDHVSMGTIASRHAYQIIANTRRVLAVEAICALQAVEYRGAEHCASYT
                     KQLYLEMRNIVPSIQEDRVFSIEHLSDWLKKESFLSNEHHQKLMTNEGGLTR"
     CDS             complement(15517..15963)
                     /locus_tag="ctg4_56"
                     /transl_table=11
                     /translation="MTLHKDRRIGRLSVLLLLHESEESQQISRLERDGWKVCLGRVGSM
                     DAHKVVAAIETASKKSGVIQSEGYRESHALYHATMEALHGVTRGEMLLGSLLRTVGLKF
                     AVLRGNPYESEAEDDWIAVSLYGTIGAPIKGLEHETFGVGINHI"
     CDS             16205..17611
                     /locus_tag="ctg4_57"
                     /transl_table=11
                     /translation="MKTSFFRVCLISAAVIGFTLPQAKAQHPVFSEVSVHDPSVIKTGD
                     TYYVFGSHLASAKSKNLMQWQQISSSVNNNNPLIPNVYTELKETFDWAQSDTLWAPDVA
                     QLADGKFYMYYNACKGDSPRSALGVAVSDKIEGPYKNKGIFLKSGMEGKSEDGTTYHAN
                     VHPNVVDPQTFFDHKGKLWMVYGSYSGGIFILKMNPKTGFPLPNQGYGKKLLGGNHSRI
                     EGPYISYNPETKYYYLYLSFGGLDASGGYNIRAARSKYPDGPYYDAAGHNMLDAKGKDG
                     SFFDDKAIEPYGVKLMGSYTFASQSEKGKGYVSPGHNSVFYDGKTKRSYLIFHTRFPNR
                     GEEHEVRVHELYMNKDGWPAAAPYRYAGEPDTHISAAAAPGTYKLIQHGKDITAAIKTP
                     KTIRLNNDGTISGEMTGTWTITGSSKAKINLNGTNYDGVFLKEWDSAREKEVVTFSVLS
                     GDGEAVWGVE"
     CDS             complement(17695..19506)
                     /locus_tag="ctg4_58"
                     /transl_table=11
                     /translation="MLERQLERNFLGNLLNIVLEKAAKEGNFQNVFLNEMLKYIDSEND
                     PNILYPPYKNTHKKILVNAYSNIKEESRLQLYVVDYDSEQSEDEMLTITMSEINSIAEK
                     AKRFYTNAKLLFNNIDPSQESHSLARTIIENDINNIDIIVVTNRFYRSNKMVKLNIPGI
                     NEVHVHVWDVERAYQLYSADNGDQLTFIDFKSQFDETFEMMYVPDNKAKNFECYIGFIP
                     AELLAKIYNFWGPKLVERNVRSFLQARAQTNRGIRDTLKNPEERKMFVAYNNGISSVAR
                     SGDIEKSAEGINLYTIKGLDGWQIVNGGQTTASIHRAYLEGIDLSDVYIQTKLTILKVS
                     SKNEDERIKLEDNMVAKISEFANTQNKINKSDLLANTRFMSEIEMFSRSTWIPVHDGRK
                     AGEKWYFERTRGQYMVDVNRFKKDKGSNNFKKQNPSDKVLSKVDLAKYFMSWEGFPHIS
                     SKGGEAAFKEFMEHNSLYWKTEKNEDGRKSLSLDDYKKLIARVIINMRVHEIVSEQKLK
                     GYRANVVYYSVAILKEIYGDQISLIKVWENQKLSDVWNPIIATIANVTLNYLRDSAGER
                     NVTQWAKQEACWDEFKKEHKSTLQYLR"
     CDS             complement(19515..20534)
                     /locus_tag="ctg4_59"
                     /transl_table=11
                     /translation="VVSIKNEFTEMFNESMHPVQPAPLKLRLVLVDPVAVFAGINPSSE
                     QRILFITAGKKAWGKEQIISLPKWKGMTISFDFHFKIGPFENEYVVAISQEKGYDTDVF
                     VSVLQNILETITLKAETEELYPLLYRTLDKWKAFFSKGGYKKLTEEQQKGLFGELYYIK
                     KWIEKNPGIPPTLINCWEGPLTGRLDFNMLHHCIEIKTVTEKIGKKVKISNETQLTLTE
                     AVQSIYLYVCFIENSQTHGTSLDSMVNTIRDLIESMSQEILLVFNELLIKAGYRDGEYA
                     ENLFAINSVEVYDANENFPRILPESLHSAVSHVSYSIDLKACEEFLLQENRAYNTKWS"
     CDS             complement(20515..23196)
                     /locus_tag="ctg4_60"
                     /transl_table=11
                     /translation="MNINFNLLDFHFQTIHSSMEAHGHNRDQAAEEAFDYALNILNIKE
                     ISQTEREKAKAKIFFKYKIGMELPNKISVLDGKNRDNWYSPSKKVTFYFWNRYRRYLLD
                     KKQWDFETVDSIDKSTDKILEFLGNPENPNPFDKRGLVLGYVQSGKTANFTGLINKAFD
                     VGYKLIIVLAGIHNDLRTQTQIRLEEEVVGNRTDKSGCPVGVAEIRPNNDDHIIGTWTT
                     EKHDISARTTPQVSHLNKPTLMVVKKNKSVLETLIEQLINHRRLYQLDIPVLIIDDEAD
                     QASIDTADKIKEEEPKTINKLIRQLLDIFPRRNYVGYTATPFANLLIDVTSETEAEGKD
                     LYPKDFLIGLPKPTGYCGPEEFFNTEENSNYSKPSLIKYLDSDEEKLIGSIKKVDDLEI
                     FDSVPSQMKKAILSFLITIAIRNLRGQKKKHNSMLIHISRLKGVQTYIKDVIAEEFASY
                     TDSILYDQYSPIIDELKFIYDHEITKTTEEWDNSIKTFEWNTVLKEIKKSIITVQLFAI
                     NGDSSDALDYHSYKEDGLNVIAIGGDKLSRGLTLEGLSITYYTRNTLMYDTLMQMGRWF
                     GYREGYIDLCRIYTSKTIANHFEHLAIAMQKLREELDYMAEKNKTPMQYAVRMLSHETM
                     RLTSLLKMKMATNYNARFDASLQQTRVFNASETFFRNNMKAVSDLVSNLTFSTIQRKKS
                     LYHLAKNVNIHTILKFFQKYQTSEHATIVKSNLLSNYIALANKENNELENWTVAVFEGQ
                     MSNHIVPNHPVKLGSLYLSNTVMRGEKAHEYNKSRELVDIRAIVADNQEFLDLDEKKLV
                     TSKSKRKMREERDKTQGFLMIYPLNPNVKIFSDLEIKFSEELVPIGVALSFPGTNIEND
                     KVYQINSTVPQVQGEQSGFNKK"
     CDS             complement(23193..24650)
                     /locus_tag="ctg4_61"
                     /transl_table=11
                     /translation="MNIILTRPSAAPVLHALRSIGYKAKTAIADIVDNAIDAQASKITL
                     HFEYDKLNGYIKIEDNGNGMSEEEIQTAMNIGAKDPRTKRSPNELGRFGMGLKTASFSL
                     GKRLSVITKKDGVYHERCWDLDYVSECNEWNLLTSIPTPVKEVAGEINGSSGTVIIIDK
                     LDRYMRNKKIQRKTFFSKTAQIQKHLEFVFHDLIDNNKIIISINDVELTPWDPFMTEHP
                     SIIEGEETLWKLDGHKMKVKYTILPHASKLTRTEFKKAGGERGWRDHQGLYIYRENRLL
                     HYGDWRNLFPKDTQSQLARVRIDISNEADSDWHVDVKKSMVTIPEQAIKILRPIAKEAR
                     DISREISYFRTQSSIAGSKIKGSLNTWEQSGKDSESPFVLNKSHPIYLELLKMLNEEQA
                     RMLNFFLKLIEIGSPVNIIAVPQLEDEIQNFTDQQLEMVHRFAETMTQLGLLNTKKEII
                     EALMTQPGFEMFNKSTLKYILEKESKE"
ORIGIN
        1 tgacctcttg agaaatctgt ttcatggcac ccgatttgat gatgtctttt tcaattttag
       61 ccggcgcttt taatccgagc gcgttataaa cggcctggcc gccgcggccg gaattgtcat
      121 tgaaaatcca gatctcgcct ttgtccgtcg tttcataaag gccgactgtc gtatctttgc
      181 cgatcacatc tttgagccgc tttcgatcgg cttcagcttt tttgttgaag tctgccataa
      241 agcttttggc tttatccttc gctccggtaa tgtcaccgaa taggctgacc gtatctttcg
      301 tattttttgc ggtgttaaaa ggaatgacaa tcgttggcgc gattttcgat agtttctcgt
      361 attggtcatc cttcatcagt acgattaaat ctggcttcag ctgcatcact ttctccacat
      421 tgacgggatt gccgacgtcc gtgatgtgtt tcagctgtgt tttgataaac ggatttttga
      481 aagcccatga gcccgccccg acgacatttg cgtcaacgga cagcagctca cccgcataaa
      541 agtcagtgac gatccgcttc gggtgtgcgg gtatatcaat atttcctttt gccgattgat
      601 atgtacgcat gtctgtcttc tctttacctg atgctgatcc gctgttttcc ttcgcgccgc
      661 tgcaggcgct taaggcaaaa acgagcagaa gtgccaggcc gatcagccat gattgtttct
      721 tcatcatgat ccccctcatt aaatgataat gattatcatt attaatatag caggaagacc
      781 tcattccgtc tatgtttttt atagaaaacc ttccttgatt atccatgtta tagtagtaaa
      841 ggagggatga atgttgatta cgaaaagagg gaactggtgg gaagtgctgc acagctggtg
      901 gctgctgctg actctcgtac catttgcgct caccgctttc ttggcctttt tctatatcgg
      961 ctaccgggcc aagaacaata aatggctgaa atacggtctt atctatttta ttattttagc
     1021 aattgctttt gtgctgccga gcacacccgg cgtgtatatc gtgctgcctt tatgggtcat
     1081 ctccatcatc cacggtctga aggtgcgggc ggcttatttg atacagcttg atgtgtttaa
     1141 acaaaatgtc gaagcaagag cgtatgaagc ggtaagacat gaggcggaag caaaattcgg
     1201 cagaaagccc gctcatcgca ttgatctgac aaaacaacga taaaaacaaa tgacaaagcc
     1261 gatatccttg cgctttgtca tttgcatgat cgggctactg ctggtatgaa tgctgttgga
     1321 acggtgtgtg atgctgggtt tgcgggaatg aagaaacatt cgtgtttgtc atcggtgaag
     1381 gcatgtgtcc gcttacgtcc tgctgcagct gattgcacac attcacgatc tgctgacatt
     1441 tttgaatggc catttcatgc ccctgaagcg cttgctgaat ggtatgaacg gcatgctgct
     1501 catggttaag catctgctga agcatttgaa tattttgctg ttcctgctga agcatttgct
     1561 tgtactgctg gctgctttgc tgtgtctgct gaatcagctg ctgtgctgtc tggcggcatt
     1621 gctggagctg atttccgctg tattggtttt ggtacatcat gaaaacctcc tggaatgatt
     1681 gattttacat atttatcatg tgaaagaatg tgggaggcat tcatgcaagc aggggattca
     1741 aatatttacc tgttatgtac agagcggaat acaaggctcg ggaatggcct gtcgagcttt
     1801 gtattccggc cctttttctc agaagccgcc ttctgtagcg tgaaaaggga tattgagtct
     1861 gttttcaacc gcgcgcaggc gctgattcaa gcggtttaag cggcgggaat ggatctcaat
     1921 tgcctggctc agccgtctga cctgctcgct catccgtgtg atttcccggt tttggcgctg
     1981 gtcttcattt gagagacggg tgagctctct cgtttgctca gcgttttgtc tttcaagctg
     2041 ggcgactctc cgttctaaag ccgtcggctg ccggtcttca ggctggtagg gcgcataata
     2101 agcttcctgc tgatacggct catactcaac acggttcact tcgaattcct gctgctgagg
     2161 gaaataggca ggaggggtat agtactgata tgggttcatt catcattctc cttatctagt
     2221 gaagtcttta tacactatgt agtcaattgc acagtgccac ggcacccgcc taacttacag
     2281 gcgtaaaaaa gcttcgaagg aaggtgatca tgttgcggaa tatacggatt tttatcatgc
     2341 cgattcttgt tttcggatgc gtcatgatga cgggctgcca gctaaagaaa gcagacgata
     2401 ccccttttta ttacgggaca tgggatgcag ggcttgagcc gggaccgatg gacggggtca
     2461 gatctgaaac cgtcacgttt acgaaagaca gagtcctgac aaagcaggtc atcaaaggcc
     2521 gcggcgaggt tgacatgccc tcagatgctt acaaggtgat atcacaaaac acggacggaa
     2581 cgatcgaaat tgaatacctc ggacatccgc atcccgtcaa aagcacgttg aaaagaggaa
     2641 aaaataatac gctcatttgg aagatatacg gaggaacaaa aacaatgaca agaataaaaa
     2701 ccggcgggga ggatgcacat gcgaaataag gctgccgaca gactcgtttt gacgggtgtc
     2761 atcgtacata tcattcaatg gttttcagtg ttatggttat tctttatgct tttagaccag
     2821 tttgggcatt ttactattta taatcccaat gtcgtaaacg gcagcatgca gtcattttca
     2881 ttctttgata tgatgcgcgc tcttctgttt tccggcacgc tgcggaatac gctgctgctg
     2941 tttttattcg cggcactgct catttactta tgggtgaacg ctctgtttat cctgttagaa
     3001 atcgtttcat atatcatgat cagacggaac agccgttcat tgtgggcata ctttcccgca
     3061 gcgatgggaa taaagcttgc ccttctggac atagcggctg tccctttctt tgcggcgggg
     3121 ctgattctct taaagcagaa aacagagaac ggcgaacaag ccgacaagag gaaaagacgg
     3181 ccgcgtatcc ggaaacaagc ccggtatatg aagagaaggc ggagaaatcc gtccgtttga
     3241 tttttcattg aaaagaaaaa acgatatgat gaaagtataa gaagaaaagg atcacaaagg
     3301 agatgcagga tgtacaagtt aatcgcaata gatatggacg gaacactatt aaacgatcat
     3361 catgaagtaa cggctgaagt ccgcggggcg cttgatgccg ccaaagcgga aggggtcaat
     3421 atcgtcctgt gcacgggacg gccgatcggc ggcgtgcggc ggtatttgga agagctgaat
     3481 ttacaggaag aaggcgactt tgtgattgct tataacggcg ccctcgtcca aaatacgtat
     3541 acaaacggtg tcgtggccga gcagtcatta ggctttgaag atttagaggc gcttcacgag
     3601 ctgagcttac agctggatac cccgatgcat tactttgaca cagccaatct gtacacgccg
     3661 aaccgggata tcagtgaata cacggtatac gaatcataca ttacaaaagt gccgcttcat
     3721 ttccgcacga tcgatgaggt gccgaaggat attctcattc cgaaaatcat gttcatcgac
     3781 gatccggaca agctggagaa aacgatcgct tccattccgg aatcattcaa ggaaaaatac
     3841 acaatggtca aaagcgcgcc gttcttccat gagattcttc accctgaagt gagtaaagga
     3901 aacgcggtca agctgctggc tgaaaaactt ggcattgaac aaaaagatgt catggcaatc
     3961 ggcgataacg gcaacgacat gtccatgatt cagtgggccg gctgcggtgt ggcaatggcc
     4021 aatgccatcc cggaagtaag ggacattgca aattttgaaa caaaatcaaa caacgaacac
     4081 ggcgtagcgc atgcgattca ggagcttgtg ctgaaaaaat aggcacccca tcagagggtg
     4141 cttttttacc gtgtgttttg gtgatatgat aagcggagag gggaggcgcg atatggatcg
     4201 tgaaaaacag cagctcagca tagaagcggc aaaattatat tatcaatcag attacagcca
     4261 gcagcagatc gccgagcggc ttaatctgtc acgccccacc gtttcaaggc tgcttcagta
     4321 cgcaaaggaa aaaggatatg tccaaattcg cgtcatggat ccgtttgagg atttggatga
     4381 actcggcgcg aagctggaag aaaaatacgg gctgcttgag gcgcacgtcg tcttttctcc
     4441 aagtgacgat tacccggcca ttacacatta cttaagccgc tatggcgcag actatatgca
     4501 taaaaccgta aaggacggcg atatactcgg cgtaagctgg gggacgacga tgtaccagat
     4561 cgcaagccgt atggaaccga agcaggtaaa gagcgttgaa gtcgtgcagc tgaaaggcgg
     4621 catcagccat tccaacgtca atacgtattc gtctgagaca attcagctgt tcgccgaagc
     4681 atttcagacc atgccgaggt atttgccgct gcctgttata tttgacagcg ccgatgtgaa
     4741 acagatggtc gagcgggaca gacatattaa gcggatcatt gaaatgggca gacaagccaa
     4801 tatcgccctg tttacggtgg gaaccgtccg ggatgaggcg ctgcttttca gactcggcta
     4861 tttccgggaa gaagaaaaac aattgctgaa agcgcgcgga gtcggcgata tttgttcgcg
     4921 cttttttgac gcggaaggca ggatttgcag cagcagcatt aacggccgga ccatcggagt
     4981 ggagctcagc gacttgaaaa tgaaagagcg ttccattttg gtggcgggcg gcagcagaaa
     5041 atgcaaggcc attcacggtg ccctgacagg taaatacgca aacgtgttga ttaccgatca
     5101 gcatacggcc aagaaactcg ttcaagaatt gtgacaatta atgaacataa tttcaattac
     5161 caatttacat atgttcaaaa ttcggttatt ctaaacgtat cctaggaaaa aggaagtgca
     5221 tacaatgtca attgcaagtc aaatagacca tactgctttg aaaccgcata cacaaaaagc
     5281 ggatatatta caactgataa aagaagcaaa agaatataaa ttcgcttccg tttgtgtgaa
     5341 cccgacttgg gtcaaactcg cagcggagga gctgaagggt acgggagttg acgtttgcac
     5401 cgttatcggg tttcctctcg gcgcaacgac ttcggaaaca aaagcatttg aaacgaagga
     5461 tgccatctca aaaggagcca ctgaggttga catggtcatc aatatcggcg cattaaaaga
     5521 cggcgatgat gaagcggttg aggctgatat ccgcgcggtg gttgaagcag ccgataaaaa
     5581 agcgctcgtc aaagtgatca ttgaaacatg tcttttgaca gatgaagaaa aagagcgcgc
     5641 atgccgctta gcggtatccg cgggcgcaga cttcgtcaaa acgtctaccg gtttctctac
     5701 aggcggggca acggctgaag atatcgctct tatgagaaaa acagtcggac cggacatcgg
     5761 ggtcaaagca tcaggcggca tcagaacaaa agctgatgtt gacagcatga ttgctgcggg
     5821 cgcaagccgg atcggcgcaa gcgccggcgt ctctatcgtg agcggcggag acagcggcag
     5881 cagcgactat taagcagcag tgcggaagcc gaaagcttcc gcaatcctct ttctttgttg
     5941 atgcataaaa aattgtaagc gaatacaaac aaaaggagaa cacatatgaa gtatttcatc
     6001 ggaattatcg gaatcattgt gtttttaggt cttgcctggc tcgccagcaa cggcaaaaaa
     6061 agaatcagaa tccggccgat cgccgtcatg ctcgttttgc agctgattct cggttacatt
     6121 ctcctcaata ccgggatcgg gaattttctt gtcggcggat ttgccaaagg atttaactac
     6181 ttgctggaat atgcatcaga agggattaac tttgtattcg gcggacttgt gaatgcgaaa
     6241 cagacgacat tcttcatgag cgtgctcctg ccgatcgtct ttatatccgc tttaatcgga
     6301 atattgcagc attggaaggt tctccctttc atcacgaagt atatcggtct tgcattaagc
     6361 aaggtgaacg gaatggggaa aatcgaatct tacaacgctg tcgcatccgc gattttgggt
     6421 cagtcggaag tttttatcag cttgaaaaaa cagctcggct atcttactga acagcgctta
     6481 tacacgcttt gcgcatccgc aatgtcgacg gtctcaatgt caatcgtcgg ttcttacatg
     6541 atgatgctga agcctgaata cgtcgtgacg gcgcttgtgc tgaacttatt cggcggattt
     6601 atcattgctt ctatcatcaa cccgtacacc gtcagcaaag atgaggattt gatcgttgtt
     6661 cctgaagaag aaaaacaatc ctttttcgaa gtgctcggtg agtatataat ggatggattc
     6721 agagtcgccg ttgtcgtagc ggcgatgctg atcggatttg tcgcactcat tgccctggtc
     6781 aatggcgttt ttaacgcggt cttcggcatt acattccagg cgctgctcgg ctatgtattt
     6841 gcgccattcg cgtttttaac cggtattccg tggaatgaag cggtgagtgc cggaagcatt
     6901 atggcgacga aaatggtatc gaatgaattt gtggcgatgc agacgctctc atccggcgat
     6961 ttccatttca gtgcgcatac tcaggcagtg gtatctgtat tccttgtctc atttgcgaat
     7021 ttctcttcta tcggaatcat tacgggtgcg gtgaaagggc tgcatgaaaa acaaggaaac
     7081 gtcgtcgcgc ggttcgggct gaagctgctg tacggggcaa cgctcgtcag cttcctgaca
     7141 gcggcgatcg tgggattgat tcactgaaca taattgaagg acaggtgata tatcatgaga
     7201 atggtagatc ttattgtaaa aaaacaaaac ggtaaagaac tgacaacaga agaaattcaa
     7261 ttttttgtaa agggatatac ggacggaagc attcctgatt atcaggcaag cgcgctggct
     7321 atggcgattt actttcagga tatgacggat caggagcgcg ccgatctgac aatggcgatg
     7381 gtgaattcag gggaaacgat tgatctctcc gccatcgagg gcattaaggt cgacaaacac
     7441 tctacgggcg gagtcggcga cacaacaact ctcgtactcg caccgcttgt cgcggcgctc
     7501 ggcgttcccg tcgctaaaat gtccggccgc ggccttggcc atacgggagg aaccattgat
     7561 aaactggaag cgatcgaagg ctttcacgtg gaattgtcaa aagatgaatt catcaagcta
     7621 gtgaaccgtg acaaggtagc cgtcatcgga caaagcggca acttgacgcc cgccgataaa
     7681 aagctgtatg cccttcgtga tgtaacgggt acggtaaact ccatcccgct gatcgcaagc
     7741 tcaattatga gtaaaaaaat cgctgccgga gcagatgcca tcgtgcttga cgtcaaaacg
     7801 ggagccggcg cgtttatgaa gacggatgaa gacgccgtga acctcgccaa agcaatggtc
     7861 cgtatcggaa acaacgtcgg ccgccaaacg atggctgtta tttctgacat gtcgcagccg
     7921 ctcggttttg cgatcggaaa cgccttggaa gttcaagaag ccattgatac gttaagaggg
     7981 gaaggccctg aagacttaaa cgaactcgtc ctcacgctcg gcagtcaaat ggtcgttctg
     8041 gcgaaaaaag ccgagacatt ggaagaagcg agaacgaagc tgcaggaagt catgaaaaac
     8101 ggcaaagcgc ttgaaaagtt caaagagttc ctgagcaatc agggagggga cgcttccgtc
     8161 gttgacgatc cgtccaaact tccgcaggcg gcgtacaaaa ttgacgtccc ggcaaaagaa
     8221 gcgggtgtcg tttcagaaat cgtcgctgac gaaatcggcg tcgcagcgat gctgttaggc
     8281 gcgggacgtg cgacaaaaga ggacgaaatc gaccttgccg tcggtatcat gctccgcaaa
     8341 aaagtcggtg acaaagtcga aaaaggagag ccgctcgtca ccctttacgc caaccgcgaa
     8401 aacgttgacg acgtgacctc caaagtctat gacaacatcc gcatctcaga aaaagcggaa
     8461 gcgccgaagc tgattcatac gctgattacg gaataagaaa agaaaggcac atacctcatc
     8521 agtatgtgcc ttttttatgg catggtttta tccaaatgaa tgtcacggac gggctgtttc
     8581 ggctgttttc ttctcaaaaa acgaatgagg tagcacaaga tcatacatgg aactccgcag
     8641 aagagggcga ttctttgatt gggatcaaat gcaaggccta cgcatgaagc gaaacacaag
     8701 atcatggcag cgatcggaac gagagggtat aacggcgtgc ggaaggtcag atccgtgaga
     8761 cggccgccgt tttttacata atgttttcga aataacagct gagacagggc gatgctcatc
     8821 cacaccacga cgcctgcaaa tccggctatt gccacaagca ccacgtagac cgttcccggg
     8881 gcggcgatgc ttgagatcaa ggatatgcag gaaacggcca tgctggcgag caaggcgttc
     8941 agcggaatgc ctttaggcgt gacttttttg aaccgggcgc tgatcatgtt ttcattagca
     9001 agtgaccaca gcatccgggt ggaagcgtac agtccagaat tggcgacaga aagcaaagcc
     9061 gttaaaatca cgaagttcat gatatccgcg gcgtaaggga ttccgatctg agaaaagacc
     9121 gcgacaaacg ggctttcaat cacacctgct tccttccatg agatcagtcc ggacagcaca
     9181 aaaatggcgc cgataaaaaa gatgaccgtt ctccaggcga catttcggat cgaacgcgga
     9241 atatcttttt ccggattggc ggtttcaccc gcggtaatgc cgatcagctc cgtccctgaa
     9301 aaggcgaagc ttacggaaat cattgcgatg aaaaccgcaa gaaagccatt cggaaacagt
     9361 ccgccgtgtg aggtgaaatt tgacagcatc ggagcttccg ccgaaccgtg caacgaaatc
     9421 aggccgaaca tcgcggcgcc gcctaagatg ataaataaaa ggatggtaac gattttgacg
     9481 ctggaaaacc aaaactccgt ttctgcaaac agtttaacgg agaatgcatt ggcggcaaaa
     9541 agaagggccg cgaaaatcgc gctccacatc cagacgctgc tgtggggaaa ccagcgctgc
     9601 ataagaatac ccgaagctgt aaattctgag cctaccgtca ccacccaatt cacccaatac
     9661 atgataccga ccataaagcc cgtagacggc ccgataaacg ttgtcgcata cgtttgaaaa
     9721 gaaccggtca caggcatggc tactgacaat tctccgagac actgcatgac aagatacatc
     9781 atcaagccgc cgattaagta ggcggcgatc gtcccgcccg gcccggcctg gcttaacgta
     9841 taccctgtgc tcaaaaaaag ccccgtgccg atgacgcccc ctaatgaaat cataaataag
     9901 tgcctgcttt tcatcgtgcg cttcaattga ctgccgcctt tatcaacatc cattgtgatc
     9961 tccccctttt ttcgtggcat gagaatacgc cggtagcctg ttaacgtgac tgtttaaatc
    10021 cctttaatgc atgtaagatc acgtgtgcgg ctgcccggct tgtcatatcg cgaaaatcaa
    10081 gtgtcggatc aacctcaacg atctcaatac cggagatgtc agcctcctgc gctaaaaatc
    10141 tgaccgcctg aagcagttcc tcggtataca ggcctccggg gccgatcgca ggacagcctg
    10201 gcgcatgggc ttgatccagc acatccatat caaccgaaat gaaaatggaa tccgctcttt
    10261 tttgaacggc cggcaaggcg tcttgtatcg ttcggagaag ccctttctcc cggatcattt
    10321 ccattgtatg cacttctgcc tgccgatctt ttacatattc ttcatatgcc aagctgttgc
    10381 tgaactctct gattccaagc tgaatcaggt tttggccgct tatgatgtta tcatctaaca
    10441 gccggcggaa tggggtgccg tttgtcggcc ctccgtcttc tgtgttgcgg acgtcgtggt
    10501 gggcgtcgaa ttgaaagacg gccgctgttc ctttcgtttc cgcaatggct ttgatggtgg
    10561 aataactgat ggagttgtcg cccccgagaa tgacgggcac ccagtcaggc tggtccgcca
    10621 gaatgccatg aatggtctga taaatgtgct catgagattt gacgatatcg gtgacatgaa
    10681 tctgaatatc gccggcatcg tataaatggt caatgacatg ctcccgcagc tccgcggaat
    10741 aagcggaaat gccgccgagc gccttgcgga tcgcaccggg agcaaagcag gcgccggaat
    10801 ggctgattga cgacttagaa agcggagcgc cgatcaaagc cggcccttta agcggctggc
    10861 ccgcccacgc ttccgtcaca tcgccgatcc ttgtcacatg ccggtcgttg aagagcgagc
    10921 cggctttttg caaaaacgga tacttatcca agagcggctc cctcccttga aatgaccgtc
    10981 tttccgttct tgatgacacg gtgcacatga ttgacgccgt aatgatacgg aatatacata
    11041 tagttcggcg cttcccaaat gacaatgtca gccagccggc cggctttaat ttgtccggcc
    11101 tcttcgcctt tcccgatcgc ataagcggcg ttaacggtga cggcgtgcca gatttcttct
    11161 gcggtcattt ttaaatgaag tgcggcaatc gacatgatga gctggaggtt ttccgtcggt
    11221 gagctgcccg gattgaagtc agtcgccaaa ctgacccgca cgcccgcatc aatcatctca
    11281 cgggctctgg cataggtgtg tttgccaaga tagaaagttg tgcccggcag caggacggcg
    11341 atcgtcccgg actctgcaag cttgcggatg ccttcgtcag atgcccccac cagatgatcg
    11401 gctgaaactg cgtccagctc tgccgccaat tccgcgccgc cgagcgggtc aatctcatca
    11461 gcatggattt tcaggccgaa gcccgcttca gccgcttttt gcaggtagtc ccgcgactgg
    11521 ctgacggtaa agacgcctgt ttccgtgaaa atatcggcaa attgcgcgag gcctttttct
    11581 tttatttcag gtaaaagctg cagcatacga tccaggaatt cgtcagggct gttccggtac
    11641 tcaggcggaa tggcatgtgc tcccataaag gtcgtgacaa ggtcgaccgg ctggcgctca
    11701 cccagttttt tcgccgcggt cagctgtttc agttcagtgt ctttgtcgag tccgtatccg
    11761 ctttttactt ccgccgtcgt gatgccgtat gacagcatgc gtccgaggtg aaaaagccct
    11821 ttttcaatca gttcttcttc ggaagcggct ttcgtatcta tgaccgttga caaaatgccg
    11881 ccgccttgcg ccaaaatatc caaataggat ataccctgaa tttttaaatt caattccttt
    11941 tcgcgggagc cgccgaatac aagatgggta tggggatcga cgaggccggg ggtgacgagc
    12001 cttcccccac agtcgatcat gtctcttgcc tcgtatcctt cctccgctcc tttatgtccg
    12061 gcaaaaacaa tgtgcccgtc gtgaatgccg ataacggcat cttccgtgac ttgaagatcc
    12121 tgcatgcttc cgcctgcgcg ggggccgccg gattccatcg ttaacagctg gccgatgttg
    12181 gtgagaatcg tatcaatctg tttcggcatg ttaccgctcc tttttcatcg gtatcataat
    12241 gtcttgttcc tcggcgactt gagccgcttt ttcatatccc gcgtccgcat ggcggataat
    12301 acccattccc ggatcgcttg tcagaacccg ggcaagccgt tcttccgcaa gccgggtgcc
    12361 gtcagcgacc gcaaccattc ccgcgtgaag ggaatacccc atgccgacgc ccccgccgtg
    12421 gtggaaagaa acccagcttg cgcctgaggc cgtgttgaca agcgcgttca gcaccgccca
    12481 atcgccgact gcgtcacttc cgtctttcat cgcttctgtt tcacggttcg gggaggcgac
    12541 tgatccgcag tccaaatggt ctcttccgat gacgatcggg gctttcagct cgccgtttct
    12601 gaccaattca ttgatggcga ggcccatctt ttcccgttcg ccatagccaa gccagcaaat
    12661 gcgggacggc aggccttgga atgtgacttt tttctgcgcc atgtcaatcc agcggtgcag
    12721 agctttattt tcgggaaaca gctcttttaa taaagcgtcc gtgcggtaaa tatcttctgg
    12781 gtccccagac agcgcggccc agcggaacgg cccttttcct tcacaaaata aaggccggat
    12841 gtaggcgggg acgaatcccg gaaaatcaaa agcatcggcg aggccttcat ctttggcagc
    12901 ctggcggata ttgttgccgt aatcaaagac gatggcccct tttttcttga aagcaagcat
    12961 ggcttccaca tgctttttca tactctgttt agagagtctc acgtataatt cgggctgctc
    13021 ccggcgcaga cggtcggcct cttcaagtga gtatccggcc ggaatatagc cgatcagcgg
    13081 gtcatgggcg gaagtctgat cggtcacgat gtcaatatgg actccgcggc tcagaagctc
    13141 atgatgcacc tctgccgcat tgccgagaag gccgatggac aaaggctttc cggcttgttt
    13201 ggctgactcg gcccagcgca gcgcttcgtc aatggacgcc gttttccggt cgcaatagtt
    13261 tgtttcaatc cgcttatcga tccgtttttc atccgcttca acggcgatga cgacgccatc
    13321 attcatcgtg acggacagcg gctgtgcgcc gcccattccg ccaagtccgg ctgtcagcgt
    13381 aacggttcct ttcagactgc cgccgaaatg ctgtctcgca agttctgcaa aggtttcata
    13441 agtgccctgc aaaatacctt gggagccgat ataaatccag ctgccggccg tcatttgccc
    13501 gtacatcatc agcccttttt tctcaaggtc atggaaatgc tcccaatccg cccatttcgg
    13561 cacgagaacc gaattggcca aaaggacgcg gggcgcgcgg ctgtgcgtgc ggaacagtcc
    13621 gaccggtttc ccggattgaa tcagcagtgt ttcatcatct tttaacgttt tgagggagcg
    13681 ctcaatcgcg tgaaaagcat cccagtttcg cgcggccttg cctatgccgc cgtatacgat
    13741 cagatcctcc ggcttttcgg caacctccgg gtcaaggttg tttcggagca tgcggagcac
    13801 agcttcctgt tcccatccta agcattcaag ttcggtgccg cggctggcgc ggattgattt
    13861 ctttacttca gtcatcttgt aagtccccct tcattggtca tcagtttttg gtgatgctca
    13921 ttcgacagaa aagactcttt cttcagccag tcactcagat gctcgataga aaacacgcgg
    13981 tcttcttgta tggacggaac gatgtttctc atttcgagat agagctgctt tgtgtacgaa
    14041 gcgcaatgtt ctgcgccacg gtattccacg gcttgcagcg cgcaaatggc ttcaacggca
    14101 agcacccgtc tcgtattcgc gatgatctgg taggcgtgcc ttgaggcgat ggtccccatg
    14161 ctgacgtgat cctcctggtt tgccgacgaa gggatcgaat cgacactggc gggatgggcc
    14221 agggttttat tttccgacac gagggaggcc gccgcatatt gcatgatcat cgctccggac
    14281 tgtaagccgg gctgagggct cagaaagggc ggcaggtcat tcagctgcgg gttcacaagc
    14341 cgttcgatac gccgttcaga aatattcgca agctcggcag ccgccacttt gagaaaatcc
    14401 atggcaaagg cgatcggctg tccgtgaaag tttccgccag agatgatttt ggcgccgtcc
    14461 tcgaaaatga gcgggttatc cgtcgcggca ttcatctcga tttctaattt ttcttttaca
    14521 tacgctaatg tctgccacga tgcgccatgg acttgaggaa tacagcggat cgaataggcg
    14581 tcctggacac gcagctctcc ttggacagtc gtcagtttgc tgtcagacag gtaatagcgg
    14641 attcgttctg caacatccat ttgctcctga tagccgcggg cggcatgaat atcttcgtca
    14701 aacgcatcca tgatgccttg aagcccttcg atcgttaagc tcgcaatccg ttctgactga
    14761 taggccagct tttccgcctc gaggtaagcg atcagcccca tcgcggtcat ggcctgtgtt
    14821 ccgttgatca gcgcgaggcc ttccttagag gtcaggacga ccggctgaag atttgccttt
    14881 tctaaagcgt gcgccgtcgg catctggtcc ccttcgtaaa agacttcgcc ttgaccgatg
    14941 agcgccagcg cgagatgaga aagcggcgcc aaatctccgc ttgcccccag tgacccttgc
    15001 tgcgggatga ccggatgaat gcgatgattg agatacgcga gcagctgatc aatcagctca
    15061 gtccgcacgc cggaaaagcc tttcagcaag gcattggcgc gcaaaagcag catggcccgt
    15121 gatacagatt cgggaaacgg atcaccgacg ccgcacgcgt gggaaagaat cagattcagc
    15181 tgcagatcag cggcgtcttc cttttgaatc agcacgtcgc tgaacttgcc gaaccccgtc
    15241 gtgatcccgt aaatggtctt ttcttcttga acaatccgtt caaccgcagc cctgcttttt
    15301 ttcacccttt ccatgctttc agcagatgct tgagcctctt caaaatcaaa taaaacacgc
    15361 tgggcatctg cggttgtcag tgaggaaccg tctaacgtta ccatcatttc aacccctttt
    15421 tctttacttt gataaagcgc ccatacaaaa aggagctatg ccatgaaaat gatttttcac
    15481 gcatagcccc ctatcgtcta aaatctatgg gctgattcat atgtgattaa ttcctactcc
    15541 gaatgtttcg tgctcaagcc ccttaatcgg agctccgatc gtgccgtaaa gtgaaacggc
    15601 gatccaatcg tcttccgcct cgctttcata agggtttccc cgcaaaacgg caaatttaag
    15661 gccgacggta cgaagcagcg agccaagcag catttcgccc cgcgtcactc catgcaaagc
    15721 ttccattgtg gcatgataaa gcgcgtgtga ttcacgataa ccctctgatt gaatgacacc
    15781 gctctttttg gaagcggttt caattgcggc taccacttta tgcgcatcca tcgaaccgac
    15841 cctgccgaga cagactttcc agccatcccg ttccagccgg ctgatctgct ggctctcttc
    15901 agactcatga agcagaagaa ggacggacaa tcgcccgatg cggcggtctt tgtgtaaggt
    15961 catatatgct tcactcaatt cttaaatatt ctgataacta gtaactgttt tttatattaa
    16021 gtgtttgcga atcagaagtc aaaacttttt ttccattctt ttgcaaatca gattattatc
    16081 gcagtaaagc ggtacatcac gaagccggcg ctgttgatca catattcccg ccatccccat
    16141 cataaaatgg aacgttgtct tgaaagcgtt tttaagaaag aggagagcga ggagatttca
    16201 gaaaatgaaa accagtttct ttcgtgtgtg cctgatttca gcagcggtca tcgggttcac
    16261 cctgccgcag gcaaaagccc agcatccggt tttttcagag gtcagcgtcc atgatccgtc
    16321 cgttatcaaa acaggcgata cgtattatgt attcggctcg catttggctt ccgccaagtc
    16381 gaaaaacctg atgcagtggc agcaaatatc ttcaagcgtc aataacaata atccgctgat
    16441 cccgaacgtc tatactgaat taaaagagac gttcgactgg gcccaatctg atacgctgtg
    16501 ggcgccggac gtcgcccagc tggctgacgg gaaattttac atgtactaca acgcctgtaa
    16561 aggggactcg ccgcgatccg ctctcggtgt cgccgtgagt gacaagattg aagggcccta
    16621 caaaaacaaa ggcatctttt tgaaatcggg aatggaagga aaaagcgagg acggcacgac
    16681 gtatcatgca aacgtccacc cgaacgtcgt agacccgcaa acgttttttg accataaagg
    16741 caagctctgg atggtgtacg gctcttactc cggcgggatt tttatactaa aaatgaatcc
    16801 gaaaaccggc ttccccctcc cgaaccaagg ctacggaaaa aaactgctcg gcggaaatca
    16861 cagccggatc gaaggcccgt acatcagcta caatccggaa acgaaatatt actatctgta
    16921 tctgtcattc ggcgggcttg acgcatcagg cggttataat atccgtgcgg cccgctccaa
    16981 atatccggac ggaccgtatt atgacgccgc aggtcataac atgcttgacg ccaaaggaaa
    17041 agacggcagc ttcttcgatg acaaagcaat tgaaccgtac ggggtcaaac tcatgggcag
    17101 ctataccttc gcctcacaat ctgaaaaagg caaaggctac gtctcaccgg ggcacaactc
    17161 tgtgttttac gacgggaaaa cgaaacgatc atacctcatt ttccacaccc gtttcccgaa
    17221 cagaggcgag gagcacgaag tcagagtgca tgagctgtac atgaacaaag acggatggcc
    17281 ggctgcagcc ccgtaccgct atgcggggga accggataca cacatatcgg cagccgccgc
    17341 acccggaacc tacaaactca tccagcacgg aaaagacatc acagctgcca tcaaaacccc
    17401 aaaaaccatc cggcttaaca acgacggcac catttccggg gaaatgaccg gaacctggac
    17461 aataaccggc agcagcaaag ccaaaatcaa cctgaacggc acaaattacg acggcgtctt
    17521 cctgaaagaa tgggactcag caagagagaa agaagtcgtg acgtttagtg tgctgagcgg
    17581 tgatggggag gctgtttggg gagtggagta gtttaatcag agacgttatt tagaataaaa
    17641 aaactctttt tcgttgatat cttcctcacg taaaagagtt tttcaaattg ttatctatct
    17701 tagatattgt agtgtggact tatgttcctt tttgaattca tcccaacagg cttcttgttt
    17761 agcccactgt gtaacatttc gttctccagc agaatccctt aaataattta aagtaacatt
    17821 cgcgatagtt gcaatgatag ggttccaaac atctgataat ttttggtttt cccaaacttt
    17881 aattaggctt atttgatcac catatatttc ttttaggatt gctacggaat aataaacaac
    17941 gttagctcta taccctttaa gtttttgttc agatacaatt tcatgtactc gcatgttaat
    18001 aataactcgc gctattaatt ttttataatc atcaaggctt aagctttttc taccatcttc
    18061 atttttttca gttttccaat aaagcgaatt gtgttccata aattctttaa aagctgcttc
    18121 ccctccttta cttgaaatgt gagggaaacc ttcccaagac ataaaatact ttgccaggtc
    18181 tactttggaa agcactttat ctgaaggatt ttgttttttg aagttatttg atcctttatc
    18241 tttcttgaat ctgttaacat caaccatata ttggcctcta gtacgttcaa aataccattt
    18301 ttcacccgct ttacgtccat catggacagg tatccatgtg cttctggaga acatttcaat
    18361 ctctgacata aatcgagtgt tggctagaag atccgactta ttaattttgt tttgagtgtt
    18421 ggcaaattcc gatattttag caaccatgtt atcttctaat ttaattcgct cgtcttcatt
    18481 tttactgctt accttcaata ttgttaattt agtttgtatg tagacatcac ttaaatcaat
    18541 accttccaag taagctcggt gaatagaagc cgtagtctgt ccgccgttta caatctgcca
    18601 cccatcaagc ccttttatag tatagaggtt gatgccctca gcagattttt caatgtctcc
    18661 gcttctggcc acagaagata tcccattgtt ataggctaca aacattttac gctcctcggg
    18721 atttttgagt gtatctctaa ttcctctatt tgtttgtgca cgtgcctgca ggaaggaacg
    18781 aacgtttctt tcaactaatt ttggtcccca aaaattgtaa attttagcta aaagttctgc
    18841 agggataaag ccaatataac attcaaaatt cttagcctta ttgtccggta catacatcat
    18901 ctcaaaagtt tcgtcaaact gacttttaaa atcaataaaa gttagctgat ctccattatc
    18961 ggcagagtac agttgataag ctctttcgac gtcccataca tgaacatgca cttcattaat
    19021 acccggtatg tttaacttga ccattttatt tgatctgtaa aacctgtttg ttacaactat
    19081 aatatcaata ttatttatat cattctctat aattgttctt gcgagagaat gggattcttg
    19141 agacggatct atattgttaa aaagcaattt tgcatttgta tagaaacgtt ttgctttttc
    19201 agctatagaa tttatttcag acatagttat agtcagcatc tcatcttcac tttgttcact
    19261 atcataatct actacataca actgaagcct gctttcctcc ttaatgttgg aataagcatt
    19321 tactaaaatt tttttatgtg tatttttata gggaggatat aaaatattag ggtcattttc
    19381 gctatcaatg tacttaagca tttcatttag aaaaacattc tggaaattcc cttcttttgc
    19441 ggctttttct agtactatat ttaatagatt acctaaaaaa tttctttcta gctgtcgttc
    19501 caacatatta atattcagct ccattttgta ttgtaggcac ggttttcttg taataaaaac
    19561 tcttcacaag cttttaaatc tatagaataa ctaacatgag atacagcaga gtgaagagat
    19621 tccggtaaaa tacggggaaa attctcattt gcatcataga cttcaacgct gttaattgca
    19681 aagagattct cagcatactc cccatcacga taaccggctt ttatcagtag ttcattaaat
    19741 accagtaata tttcttgaga catgctttca attaagtctc taatagtatt aaccattgaa
    19801 tcgagtgatg taccatgggt ttggctattc tcaataaagc aaacatacaa gtatatagat
    19861 tgtacggcct ctgttaaggt tagttgcgtc tcattggaaa tcttcacttt cttacctatt
    19921 ttttctgtta ctgtttttat ttcaatacag tggtgtaaca tattaaaatc caaacgacct
    19981 gttaagggac cttcccagca atttattaaa gttggaggaa ttccagggtt tttttcaatc
    20041 cattttttta tatagtaaag ttcgccgaaa agtccttttt gttgttcctc tgttaatttt
    20101 ttatacccac ctttagaaaa gaaagctttc cacttatcta aagttcgata taataaagga
    20161 tataattctt ctgtttcagc ctttaaagtg attgtttcta gaatattttg taaaacagac
    20221 acaaatacat ctgtgtcata ccctttttct tggctgatag ctacaacata ttcgttttca
    20281 aaaggtccaa tcttaaagtg gaaatcaaag ctaatagtca tgcctttcca cttaggtaaa
    20341 gatataattt gttcttttcc ccatgctttt ttaccagcag taataaataa aatcctttgt
    20401 tctgaacttg gattgattcc tgcaaaaaca gcaacaggat cgaccaaaac aagccttagt
    20461 tttaatggag caggctgaac aggatgcatt gattcattaa acatttctgt aaattcattt
    20521 tttattgaaa ccactttgtt ctccttgaac ctgcggtacc gtgctgttta tttgatagac
    20581 tttatcattt tcaatattag tcccgggaaa agaaagggca actcctatcg gtacgagttc
    20641 ttcgctaaat tttatttcta aatcactaaa tatttttacg tttggattta aaggataaat
    20701 cataagaaag ccttgagttt tgtctctttc ttcacgcatt ttcctctttg atttcgaggt
    20761 gacaagtttt ttttcatcca aatctagaaa ttcttggtta tctgctacaa ttgcccgtat
    20821 atctactagc tctctggatt tattgtattc atgtgctttc tctccacgca taacggtatt
    20881 tgatagatat aaacttccta atttaacagg atggttaggt acaatatgat ttgacatttg
    20941 accttcaaat actgctactg tccaattttc cagttcatta ttttctttat tggcaagggc
    21001 tatataattt gatagtaaat ttgatttaac tattgttgca tgctcactag tttggtactt
    21061 ttgaaagaat ttcaatatag tatgtatatt cacattttta gctaggtgat ataaagactt
    21121 ttttctctga attgtagaaa aagtaaggtt agaaacaaga tctgacacag ccttcatgtt
    21181 attgcgaaag aaagtttcag aagcattaaa aactcttgtc tgctgcagac ttgcatcaaa
    21241 acgagcatta taattagtcg ccattttcat ttttaataaa cttgttaatc tcattgtttc
    21301 atgacttaac atgcgtactg catattgcat tggcgttttg tttttttctg ccatataatc
    21361 aagttcctca cgcaactttt gcatagcaat agccagatgt tcaaaatggt ttgctattgt
    21421 ctttgatgta taaatccggc aaaggtctat ataaccttct cgataaccaa accaacggcc
    21481 catttgcatt aatgtatcat acataagagt attgcgtgta tagtatgtaa tgcttaatcc
    21541 ttcaagggta aggccccttg aaagtttgtc tcctccaatt gcaataacat ttagcccgtc
    21601 ttctttatag ctgtgataat ctaaagcatc gctactgtcg ccattaattg caaataattg
    21661 tactgttata atgctttttt ttatctcttt taatacagtg ttccattcaa aggtcttgat
    21721 actgttatcc cattcttccg ttgttttagt tatttcatga tcataaataa atttaagttc
    21781 atctattata ggactgtatt ggtcataaag tatagaatct gtataagacg cgaattcttc
    21841 agcgattaca tctttaatat aggtttgaac accctttaat ctggagatat ggatgagcat
    21901 tgaattatgc ttttttttct ggcctcttag atttcttatc gcaatagtga ttaaaaagga
    21961 taaaatcgct tttttcattt gacttggaac ggaatcaaat atttctaagt cgtccacttt
    22021 ttttattgac ccaatgagtt tctcttcatc actatctaaa tacttaatta aactaggttt
    22081 actataatta gagttttctt cagtgttaaa aaactcttca ggcccacaat atcctgttgg
    22141 ttttggcaga ccaattagaa aatctttagg ataaagatcc ttgccttcag cctctgtttc
    22201 agaagttaca tcgattaaca agtttgcaaa aggagtagca gtataaccga cataatttct
    22261 gcgtggaaaa atatctaata gctgtctaat taatttatta attgtttttg gttcttcttc
    22321 ttttatcttg tccgccgtat caattgaggc ttggtctgct tcatcatcaa ttattaagac
    22381 cggtatatct aattgataaa gtcttctatg attgattaat tgttcaataa gtgtttccaa
    22441 tactgacttg tttttcttaa cgaccattaa agttggctta ttcagatggg acacttgagg
    22501 ggttgtgcga gcagatatat catgcttttc ggtagtccat gttccaataa tatgatcatc
    22561 attatttggt ctgatttcag ctacgccaac tgggcacccg ctcttatctg tacgattacc
    22621 aacaacttct tcttctaatc ttatttgggt ctgagtccgc agatcgttat gaattcctgc
    22681 gaggacaatg attaatttat aaccgacatc aaatgcttta tttataagac ctgtaaaatt
    22741 tgcagttttt cctgattgaa catatcctaa aaccagccct cttttgtcaa aaggatttgg
    22801 gttctcagga ttaccgagga attctagtat cttatcagtt gatttatcaa tagaatccac
    22861 agtttcaaaa tcccattgtt ttttatcgag caaatatctt ctatatcgat tccaaaagta
    22921 aaaagttact ttctttgatg gtgaatacca gttatctctg ttttttccgt ctaacacact
    22981 aattttattt ggcaactcca tcccaatttt atatttgaaa aagatttttg cttttgcttt
    23041 ttctctctca gtttgagaga tttcttttat attaagaatg tttaaggcat aatcaaaagc
    23101 ttcttccgca gcttgatctc gattatggcc gtgagcttcc atactggagt gaattgtctg
    23161 gaaatgaaaa tccaataagt tgaaatttat attcattctt tgctctcctt ttctagaata
    23221 tatttcagtg tgcttttatt aaacatctca aaaccaggtt gagtcattag tgcttcgata
    23281 atttcttttt ttgtatttaa aaggccaagt tgagtcattg tttcagcaaa gcgatgaacc
    23341 atttctaact gttggtctgt aaaattttga atttcatctt ctaattgtgg tactgctata
    23401 atatttacag gtgaacctat ttcaattaat ttcaaaaaaa agttcagcat tcgcgcttgt
    23461 tcttcattca acatctttaa taactctaaa taaattggat gacttttatt taaaacaaaa
    23521 ggggattctg aatctttccc agactgttcc caagtattta agctgccttt aattttgctt
    23581 ccagctattg aagactgtgt cctgaagtaa gatatctctc tagagatatc tcttgcttct
    23641 ttggcaattg gacgtaagat ttttatggct tgttcgggta ttgtaaccat tgacttctta
    23701 acatcaacgt gccaatcaga atccgcttca ttagagatgt caattcgtac tctggctaat
    23761 tgagattgag tatcttttgg gaaaaggttt ctccaatctc catagtgtaa taagcgattt
    23821 tccctatata tgtataaacc ttggtgatct ctccatcctc tttcgccgcc tgctttttta
    23881 aattcagtgc gagtaagttt ggaggcatgg ggaagaattg tatacttgac tttcatttta
    23941 tgtccatcca atttccatag tgtttcttct ccttcaatta ttgagggatg ctcagtcata
    24001 aaagggtccc aaggagttaa ttcaacatcg tttatagaaa taataatctt gttattgtct
    24061 ataagatcat gaaaaacaaa ttcaagatgt ttttgaattt gagcggtttt tgaaaaaaaa
    24121 gtttttcgtt gtattttttt attgcgcata taacgatcaa gtttatcaat tattatgaca
    24181 gtaccactag atccattaat ttcgcccgcc acttctttaa ccggagtagg tatagaagtc
    24241 aacagattcc attcgttgca ttcagatacg taatcgagat cccagcatct ctcatggtat
    24301 actccatctt tctttgttat aacgcttaag cgttttccta atgaaaatga ggcagttttt
    24361 aaccccattc caaaacggcc taattcattt ggtgatcttt tagttctagg atcttttgct
    24421 cctatattca ttgcagtctg tatttcttct tcgctcatac cgttcccatt atcttcaatt
    24481 ttaatatagc cattaagttt atcatattca aagtgtaatg tgatttttga ggcttgagca
    24541 tcaattgcat tatcaactat atctgcaatt gcagtttttg ctttataacc tattgatctg
    24601 agtgcatgaa gtactggtgc agctgatggc cgtgttagta taatgttcat aaatccccct
    24661 gtttttcaat tttttaatat aactataata aaataagttc attccaaacg tatatctttc
    24721 taaaaagatt taacaagaat tatcaaaaaa gcttgacgat atactgattt tatcgtcaag
    24781 cttgttgtta ttctaaatct aataattcat ttttaagtga gatagtaggc tcaacaccca
    24841 tagcatttaa taatgcctcg gctgctgcac gtccaagcaa agggggaact gcattcccta
    24901 cttgttgata ttgctgatct tttgtccctc taaatttaaa attatctgga aatgattgca
    24961 gacgggctgc ctcgcgaata cttattgctc tagctttttc tggatgactc cacattgatt
    25021 tccttacgtt aacgactgta ggagatggac tgccatagtc tagtcttaaa tagattgtat
    25081 tctgtgttct agacacatca gagtaggttg tttttaactc atcattaaga ctgtggaaat
    25141 ttttaccttt caattgaagt attgcttcaa aacgagtttt acttagctga cggctttcag
    25201 tatttatatg attatcaatc aaccctttat cagcatcttt tctgaaatat cgaagcatag
    25261 gcgatgcctg cgcatctgat tctatataat ctaatggttt agctttttcc atatctgtaa
    25321 ggggcgttat atcggctaaa tcctgtattg catcccttac tgtaaaaggt gttgagtgta
    25381 ccaacgcatc gggaagtttc ggac
//
