LOCUS       gnlProkkaEFAHGJHA_1    13831 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFAHGJHA_1.
ACCESSION   gnlProkkaEFAHGJHA_1
VERSION     gnlProkkaEFAHGJHA_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:47:18
            Original ID  :: gnl|Prokka|EFAHGJHA_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1367478
            Orig. end    :: 1381309
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13831
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:13078]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13078
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..13831
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13831
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(358..1002)
                     /locus_tag="ctg1_1365"
                     /transl_table=11
                     /translation="MRKISYKDMFLRHVKDHLSLYIFVSVLFFMGVIFGAIIVNSMTIS
                     QKEDLYYYLSQFFGQLSDGKQASSADMFGQSIFHNAKYLGLMWILGISVIGMPIIFIMI
                     FLKGIVVGFTVGFLVNQMGVSGFFLSFVSVLPQNVLLIPAYLIMGTCAIAFSLKLIRQL
                     FVKRSLHDAPIQWFGRYAFVLLVILFLALISSLFEAYLSPVLMEKLTSRLF"
     CDS             complement(1105..1320)
                     /locus_tag="ctg1_1366"
                     /transl_table=11
                     /translation="MAKSRARKKREHLLRNGGRDVLLSRGSSPSFSTHERMTKSKKEIL
                     NKRKCKNPYDHTVFDDKDFFVPAKTA"
     CDS             2849..2992
                     /gene="allorf_1370327_1370470"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_1370327_1370470"
                     /protein_id="allorf_1370327_1370470"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAILKLFMFQSFYGDGFLSKAVYIGSTPIFHCWKIPIDFIRFYFH
                     YE"
     CDS_motif       2849..2890
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAILKLFMFQSFYG"
                     /locus_tag="allorf_1370327_1370470_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2891..2992
                     /prepeptide="core"
                     /locus_tag="allorf_1370327_1370470_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="3957.5"
                     /monoisotopic_mass="3955.0"
                     /core_sequence="DGFLSKAVYIGSTPIFHCWKIPIDFIRFYFHYE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAILKLFMFQSFYG"
                     /leader_location="[2848:2890](+)"
                     /alternative_weights="3975.6"
                     /alternative_weights="3993.6"
     CDS             3470..3916
                     /locus_tag="ctg1_1367"
                     /transl_table=11
                     /translation="MRYFKEKQFKKDIILVAVGYYCRYSLSYRDVSEILKERGVSVHPT
                     TIMRWVHEYGNLIYQIWKKKNKNVQLSWKLDETYIKVKEIWCYLYRAIDKDGHTLDIQL
                     CKKRDHHAAYAFMKRLVKTFGEPAVLTTDKAPALLCAFNKLREI"
     CDS             complement(3808..4218)
                     /locus_tag="ctg1_1368"
                     /transl_table=11
                     /translation="MFSFAVSTILDGTSSSTSRCILEHPILPPDYKGVLTAKRGFCTLI
                     YFLGDEALIFIGTLLRSFVKVKWCQQKDEHFMRLLVAPVIHCMSKNRSLSQDFGFVYIS
                     LNLLNAQSNAGALSVVRTAGSPNVLTNLFIKA"
     CDS             complement(4484..4603)
                     /gene="allorf_1371962_1372081"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_1371962_1372081"
                     /protein_id="allorf_1371962_1372081"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSIQVSVKNTDADDLYMGCIHVAAVAEQIKEQQRMKKAS"
     CDS_motif       complement(4550..4603)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MSIQVSVKNTDADDLYMG"
                     /locus_tag="allorf_1371962_1372081_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4484..4549)
                     /prepeptide="core"
                     /locus_tag="allorf_1371962_1372081_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="2350.8"
                     /monoisotopic_mass="2349.3"
                     /core_sequence="CIHVAAVAEQIKEQQRMKKAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSIQVSVKNTDADDLYMG"
                     /leader_location="[4549:4603](-)"
     CDS             complement(4600..5199)
                     /locus_tag="ctg1_1369"
                     /transl_table=11
                     /translation="MSFSQFNIDIFLAINDLGKQYSFLNSAMVFLAEYMVYILALIIIA
                     YWFTGSRKSRMMVIQAIVAFVIAEVIGKIAGKFHLNYQPFAVLPDVNKLVDHAVDNSFP
                     SDHTILFFSICFSFWLVRKKTGWLWLILAFCVAISRIWVGVHYPFDVAIGALIGCVSAL
                     FSYWLVPKFSFIKQLLTLYERVERRVLPSKNKSKEF"
     CDS             complement(5384..5476)
                     /locus_tag="ctg1_1370"
                     /transl_table=11
                     /translation="MMFSQLAFKNISRNIRTYAAYFSSENVMLE"
     CDS             complement(6058..6798)
                     /locus_tag="ctg1_1371"
                     /transl_table=11
                     /translation="MLWNECLKIVNKRIFILSHIGFIVMTVLFSWAYTSNLKADDTVAQ
                     MVNALLGLSGMLVILPWAIVLSPLIWTDEYQYGTLKQLFLHTSSRSRLYVAKIAAMILL
                     IITSVVNIFIVSLLVNLLMAPKNIQWGDMTDVIYSIGAIVLQCCLYASLASLIGVWTRS
                     AAIAVGGSLVLYFLQMIFGGSLLSTSWTHILFIHHDDLSVYWSMSQYKSELVGVPISLA
                     IDIGYILFFFAIGLWLFVKERGAD"
     CDS             complement(6800..7750)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 179.9; E-value:
                     1e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1372"
                     /transl_table=11
                     /translation="MKTVLSVQHLTKEIKGKLIVQDISFDVVEGEIIGLLGANGAGKTT
                     TMKMIVGLSTISSGDVQIAGYSIKSQFSKALLNVGAVIEAPAFYPYLSGYENLRQYQRL
                     HKNASKDWLLEVASLTGIEHALKQRVGTYSMGMKQRLGIAQALLRKPKLLVLDEPMNAL
                     DPSGVRETRNYLNRIAADLGVAIVISSHQLSEIEQMARRVVIMQNGCLVTEQRIDDGLN
                     DGKFCITLHIDNVELTSEVVVNLFGDDYHALDYMQTQKLSNGLHTMTVAIDEGQVPKLI
                     RALCDAGVEVHRVLSAHTSLEDKFLKWTTARGEVG"
     CDS             complement(7826..9961)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 267.4; E-value:
                     4.2e-81)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1373"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.7e-40, bitscore:
                     134.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARRRIPYVEQMHQSECGLCCLAMISAYYQKEVSLSRLRERADVG
                     RDGTTLLQLKRIAESLGFGVKAYRIEHIDQLKQVSLPAILHWNQDHFVVLEKIDNNYAR
                     IVDPRFGRIKLSLKSFSEQFTGFLMTVDLTERLDVEKDQNVWLNSLVYVKSHKNLFVYV
                     FLITLALQVIIVGMPLFMKHVIDEIMIPKNSSLSITVFISIISFLLAYMLITFARSRVL
                     VRLHNALDYEMQTSFFSHLLKLPLPFFLLRSYGDMLFRMNSLATIRNQLSGTLITGILD
                     GFMLFVLSGYMLFISPLLAMVVFLLVSINILLVIFTKRYVAEINQQQVVATTEVQAVQT
                     EMLYGIMGVKISGTEQQVYSQWLNKFKHLLRVYRRKENLNSYITTTSNGLQFMSPLIVL
                     SIGVLLVTGKYSSMTVGELVSFQAIATLLFTTSSSLMNTINSYILTTTILKRTHDVLES
                     PIEQNEGKLQVKVRGDIRLSHVSFSYSKYSPKVINDISLHIKLGQKIAIIGQSGSGKST
                     LAHLMIGLFTPTSGEIYYDNHETSDLDMQYVRKQMGIVPQDISLLNRSIYDNIVLHQDG
                     VTMDEVVRVAKAANIHDEIMAMPMKYQTVLAEMGRNISGGQRQRIALARALLNNPTVLV
                     LDEATSALDHISEARVDEYLSSINCTRIVIAHRLSTVMNSDMIIVLENGKVCDVGNHSQ
                     LLHTSNYYQYYYKEMSS"
     CDS             complement(10001..13078)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     978.5; E-value: 6.4e-296)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1374"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-109, bitscore:
                     361.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.6e-63, bitscore:
                     209.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINTSEKLKYWSKFFYDKEEYLEKSLKEVSNLEVGTIINLQKNDL
                     TWKYQWEELLKGSVEDYFSTTPPVFSGFVERFLLLAIDLLEKQGTIRGLDSHILHTGKS
                     FFKSLLPSLFQRIIDFSYKTLILELNVLSDQGLLQGETSEKRYQYFENLLHDKEYLRQL
                     ANEYPELIRSLLRITEKWAVHVSEVLNRFTADYSKIVSHMPEVKQFGKLVRLHIGAGDT
                     HDGRSVTILEFTTGCKLVYKPRSLKVDKGYYRILSWMRQFGVPYMKIIENIDCGSYGWT
                     EFVEFSECKSLEEISEFYKNMGVNLAMMYMFNATDFHYENIIAHGSSPVVIDLESLFHR
                     HISTKKFEHDANGHAYEILYYSVMSSGMLPQYIYNSETYSGFDISGIFGSGGKKVPNAV
                     SLVDRGTDRMRLERSMGESGKTHNLPHYNNEVVDSYRYINDIEQGFAQAYRIMMENKHR
                     LKEMIREFDDVRVRVIVRNTRAYGELMRTLYHPDLLRDELDRKVVLHRLWLQCLADPKH
                     LKFVPYEMRDIEDGDIPIFYTCPSERDAWASNGERIPQLFEQSGIDIVINKIDKMGEKD
                     LKEQLQLLNMSVLASKPDLYSYRIPEIQLKDSNDVLGSNWKAEYVRLATSIGESLVQSA
                     IIPSNNAADDITWIGLVASGDDERKLRLIPVGNDLYNGNSGIALFLGYLSELTANNQYK
                     NMARKALQPLLEIMRDKCRSNAVSLNIGAFEVGSIGGGVFATYQLSRLWNDEELLQTVK
                     EYLPYYCELVDKDTAFDYIGGAAGAIDVLLHIYHGTGWTEALQGAEKCAEHLLQNAQTL
                     PDGSMAWFTTPNRKLYVGYSHGVSGIIASLSSLYRVTQRAEYIEYIEKGLQYERANYCA
                     ELKNWVTPNDTARVTWCHGAPGILLSRLRLLENGYWDVHIDQEINIALETTLKLGFGTE
                     PVYCHGDFGQLEILLYANSVLDRNEDTINVVRAYLLRLLNDQPWNNTGVHRAFDIKGLM
                     GGLSGIGFGLLKQAFPEEVPNILNLENDKFFSSISG"
     CDS             13398..13568
                     /gene="allorf_1380876_1381046"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_1380876_1381046"
                     /protein_id="allorf_1380876_1381046"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTQLHGERRAFQAIYSASTIYNASIILAECPPIESMSNLNGSPLR
                     YYCELTCSRIK"
     CDS_motif       13398..13523
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MTQLHGERRAFQAIYSASTIYNASIILAECPPIESMSNLNGS"
                     /locus_tag="allorf_1380876_1381046_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13524..13568
                     /prepeptide="core"
                     /locus_tag="allorf_1380876_1381046_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="1709.0"
                     /monoisotopic_mass="1707.9"
                     /core_sequence="PLRYYCELTCSRIK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTQLHGERRAFQAIYSASTIYNASIILAECPPIESMSNLNG
                     S"
                     /leader_location="[13397:13523](+)"
     CDS             complement(13588..13776)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1375"
                     /transl_table=11
                     /translation="MQWKNQMENLNAATYNPVGSVLSELTDTEMDTVAGGAQALGFTDG
                     NCLVSITADCTPWIWGC"
     CDS_motif       complement(13669..13776)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MQWKNQMENLNAATYNPVGSVLSELTDTEMDTVAGG"
                     /locus_tag="ctg1_1375_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13588..13668)
                     /prepeptide="core"
                     /locus_tag="ctg1_1375_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.60"
                     /molecular_weight="2671.0"
                     /monoisotopic_mass="2669.2"
                     /core_sequence="AQALGFTDGNCLVSITADCTPWIWGC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MQWKNQMENLNAATYNPVGSVLSELTDTEMDTVAGG"
                     /leader_location="[13668:13776](-)"
                     /alternative_weights="2689.0"
ORIGIN
        1 gacacaccgt ctccaaagtt aattttatca acgactttta attcagttaa taattcaagc
       61 gtacggtata ctgtagcgag accgatctca ggagatttct cttttacgag gaggtataca
      121 tcttctgcgc ttaaatggtc ttcttcgttt tcaagcagca ctcttactgt cgcttcacgc
      181 tgtggcgtaa gtttatagct ggatgagtgc agttgtttct taattcgatc aatacggttt
      241 tccatgtctt tccctcctac gccgcattcc atgactcatt ataacaaaat acgcgcagag
      301 ttccaactat aattattata aactgataaa taaaacggtt ttcttttaat aatgatttta
      361 aaaaagtcta gatgtaagct tttccattaa aacaggagat aagtatgctt caaagagaga
      421 tgagatcagc gctaaaaaca gaatgaccag cagcacaaag gcataccgcc cgaaccattg
      481 aatcggcgcg tcatgcaggc ttcttttcac gaacagctgt ctgattaact ttaaagaaaa
      541 cgcaattgca catgtgccca taataagata agccggaatc agcagcacat tttgcggcaa
      601 aacggagaca aatgatagga aaaacccgct cactcccatc tgattgacaa ggaacccgac
      661 agtaaagccg acgacgatcc ctttcagaaa gatcatgatg aaaataatcg gcattccaat
      721 gacggaaatt cccagtatcc acatcaggcc taaatacttt gcattatgaa agatactttg
      781 cccaaacata tcagctgaac ttgcctgttt tccatccgaa agctgtccaa aaaattgact
      841 taaatagtag tataaatctt ctttctggct gatggtcata ctattgacaa taatcgcgcc
      901 aaagatgaca cccatgaaaa acagcactga cacaaatata taaagagaga gatgatcttt
      961 tacatgcctg agaaacatgt ccttataaga gatttttcgc ataccgtttc ctcccgcccg
     1021 ctctagtgat tttttactta atagattgta tgaaagaaac agaaaaacat gccccttttc
     1081 aaaaagaaac gatagagaag gatactaggc ggtttttgcg ggcacaaaaa aatccttatc
     1141 atcaaatacc gtatgatcat aaggattctt acactttctt ttattcaaaa tctctttttt
     1201 gctttttgtc attctttcat gtgtgctgaa agatggtgaa cttcctcttg ataataaaac
     1261 atcacgtccg ccgttcctca gcagatgctc ccgtttcttt ctcgctcggc tttttgccat
     1321 gatgatcact ccctttataa ttttatatta aaacatctca aaacacaatt atcccctgtt
     1381 ctgacaaggg ataaaggcac ttgttacaca agatactgca tccgttcagc atttgtcata
     1441 ttctttagat tattgttata cgctaataat tctatatata ttataggtca aaacccaatc
     1501 actttttaac ataatgttat caaatgcaaa tacctctcaa cagagagctt taaatcaagt
     1561 ttaatgataa gtgtagcatt attatataaa gtaaggataa aaacaacaaa attagaacag
     1621 ttccaagagt tccaacaaaa cacaaagaat tagacataga gtattatata tattgagata
     1681 acctagaaaa attttaagcg aacttagaaa atttaatgac tatttttgaa tttagtttat
     1741 gattcctgat ttgagtatgt ataggctctt tttttagttg gtggtacaga tgccgattta
     1801 tttattgatg taactctata cggttttaaa aaacaaaata aaaggttttt gaactaagga
     1861 tagccttcat tcaactaata ggctatttct ttttagatga attggttata gcaactgaac
     1921 gaaaggaatt agattttaat ataaacaaat gaaaatgaaa ggttggcttt ttacaaagga
     1981 agatttggtg aagttgaata ctttgaagaa aaattcgcta agcgaaagta acattaaaac
     2041 aaagctaaga aaacttacag attatttccg aatcaatata agacatttat ctctgtactc
     2101 taacataaaa aagcaaaaga gcgtttatag cacctaacgg aaagacttta tgacaatagg
     2161 ttacttaagt actttctcta ctcctcaagg aatcttagtt aaaatcagaa tatcataaaa
     2221 gtctcctttc cagagtggag ggagattaaa cagagttttg tttatcttcc ctctagtctt
     2281 gactataatt taataaaaag cctttttaag gttcatcgtt aaggtagtat gaacttggtg
     2341 tattcagtta aaaaataaat agtatagctt tgattagacg taatacggtg gaatagttaa
     2401 accctcacca gacttatcta agtcagacag agttaaagct actaatacaa ttaatctcgt
     2461 cggattaaat aaaattgtta ctgatgatct aaaaaagaat cctcaaatag ctgacagacg
     2521 ttctttagaa cgtcgtgaaa aatgggagct agctaatact cttaaaagtc aactactatc
     2581 ccaagcaaaa gtagagagtc tagcattaga gatgtttaag cttcttgtag aatagagtgg
     2641 gatgttttcg gtttggatgt ctgtatttaa agaacttaaa ttcttcttga aagaaatttt
     2701 agatgtgttt ccaggtactg atttactaag gttaccattg aattcaatat ataacaagcc
     2761 tgtcaaggat gaatgatatc cttgtctttt tttatattaa gagacaaatt gatacgaata
     2821 tccgaattcc gtctgaaatt aacttaattt ggctatactt aagctgttta tgtttcaatc
     2881 tttttatgga gatggttttt tgtcaaaagc agtttatatt ggatcaacac ctatctttca
     2941 ctgttggaaa atccccattg acttcatacg attttacttt cactatgaat agtcccctcc
     3001 aaaaagttta atcacacatt acccaataaa cagaaaaaat tatgcgtcga tgagaatcct
     3061 cttttttcta taaatggaat aaataatgta aattattctt cagagcttcc tattcccctc
     3121 cctcattgtt tgaactcttt ttctgcaagc atcccccgaa aaggaatatt aagacaaaat
     3181 attccatatt agttatagac gaatttaggg ttcagcctta gttgttcgat ttgtaacatt
     3241 ttttcttttt aaattctaaa ctagattgta ttgaaatcag atgtaagaaa atactgtccc
     3301 aaaaataatt tgtcacaata taaaatttct gtatttttat tacattgatt gtttattgat
     3361 ttataacatt ctattttcta ttcaacatac aattggtgtt ttcggttctg ttgcaaagat
     3421 ttttaaactg agataacctg tagaaaaagt gtgagcagga gaatgatata tgaggtattt
     3481 taaagaaaaa cagtttaaaa aggatattat tttggtagcc gtcggctact attgccgtta
     3541 ttctttaagc tatcgtgatg tatccgaaat cttgaaagag cgtggtgttt cggttcaccc
     3601 aacaaccatc atgcgttggg ttcatgaata cggaaacctt atctatcaaa tttggaagaa
     3661 gaaaaataaa aacgttcaat tatcttggaa actagatgaa acctatataa aagtcaaaga
     3721 aatatggtgt tatttatatc gtgcaattga taaagacggg cacacattgg atattcaact
     3781 ttgtaaaaaa cgggatcatc atgctgccta tgcctttatg aaaagattgg ttaaaacgtt
     3841 tggagaacca gcggttctca ctacagacaa agcaccagca ttactttgcg catttaacaa
     3901 attaagagaa atataaacga aaccgaagtc ttggctcaga cttcggtttt tcgacataca
     3961 atgaattaca ggagctacta acaatcgcat aaaatgttca tctttttgtt gacaccactt
     4021 aaccttaaca aaacttcgca acagagtccc tataaaaatc agagcttcat ctcctagaaa
     4081 atatattaac gtacaaaatc cgcgttttgc cgtcagtacc cctttgtaat cgggaggaag
     4141 aattggatgt tctaaaatac accgtgaggt gctagaggaa gtgccatcaa gtatggtgga
     4201 aactgcaaaa gagaacactc taagtcccta tcattatatt cattatttgt ttgaaacgct
     4261 gcttaacatc aatttaaaca ctaaagaaga aattgataaa gtcttgctgt ggtcaaaata
     4321 attgccatct agctgtagag tgccgaaaaa agtgaagtaa acaaaaaact ccaaaatcaa
     4381 cttttattgt atattttgga atcaattgac gtttactttg tgaagaaaga gaaccgcaac
     4441 acttcctaac ctgggtgctt atcacatcca caaacacaaa agattaagaa gccttcttca
     4501 ttcgttgttg ctctttaatt tgttcagcaa cagctgcaac atgaatacat cccatatata
     4561 ggtcgtcagc atctgtattt ttcacgctaa cttgtatact caaaattcct ttgatttgtt
     4621 tttggatggt aaaacacgtc tctctactct ttcatataga gtaagcaatt gcttgataaa
     4681 agaaaattta ggtactaacc aatacgaaaa taacgcagaa acacacccta ttaaagcccc
     4741 tattgcaaca tcaaaaggat aatgaactcc tacccaaata cgagagatcg ctacacaaaa
     4801 tgcaagtata agccataacc atccagtctt tttacgaaca agccaaaacg aaaaacaaat
     4861 cgaaaaaaag agaatcgtat ggtcactagg aaatgaatta tctacagcat gatcgacaag
     4921 tttattaaca tcaggcaata ctgcaaacgg ttgataattc aaatgaaatt tccctgctat
     4981 ttttccaatc acctcagcaa tcacaaaagc aactatcgct tgaataacca tcatcctact
     5041 ttttctggat ccggtaaacc aataagctat aattattaaa gccaaaatat ataccatata
     5101 ttctgccaaa aataccatgg cagagtttag gaatgaatat tgtttaccta aatcattaat
     5161 tgctagaaaa atatcaatat tgaattgaga aaaagacatt tttcaaatcc ctcctttata
     5221 gtaaggtgta taactgattg ccatatacct tcattacatg aatagttttg attattgtac
     5281 tcatctaaaa ataccaacct tcttgtacat ttataatttt attatggaaa aaaaggttta
     5341 aatgagactt aactacttct taaatatgtg aatgtactgt tttttactct aacatgacgt
     5401 tttcacttga aaaataagcg gcatacgtac gtatatttcg actaatgttt ttaaacgcga
     5461 gctgagaaaa catcatctta cttcccctcc cacgcttttt ttactttcat aaaaataggt
     5521 atcaccatga gtatgacatt tccatctcct tcttctttct tttttttcat tataataaaa
     5581 aaagaaaaag gaaaacatcg aacttcctta caaacattcg tgtattctta caattttgtc
     5641 atttttctcg tcattttgta aatgtgttca tcgccttgcc tttcgctatt ttcaaaaact
     5701 cttgtaactc tgggtttata ttcttctttc tgtatgcaac gcctagtttc gcagcaattt
     5761 tagaatcaca tatttctttg taaacaactt ctgattgata taatttattt gcagacacct
     5821 atccgctatt aattaagtta gactgactta aatttaaaac cagcggcagt ctttgacaaa
     5881 aataaagtca tagactgccg ctggtttatt ggactagcgt aatcaattgt cacttatcat
     5941 tattggctac tttcagtttc acattcatta ttttgtcttc catacagtta tcccgagtat
     6001 cgccataaat gacataactg tatcctaata ttgctcattc ttagctccgt tttatgttta
     6061 gtctgctcct ctctctttga cgaacaacca taatccaatt gcaaagaaaa acaaaatata
     6121 gccgatatct atcgctaacg atataggtac gccaactaat tccgatttat attgtgacat
     6181 gctccaataa acacttaaat catcatgatg aatgaataga atgtgtgtcc atgatgtaga
     6241 taagagacta cctccaaata tcatttgtaa aaagtatagc actaagctac cgcctactgc
     6301 gatagcagct gatctcgtcc acacgccaat caaggatgct agacttgcat ataggcaaca
     6361 ttgcaatacg attgctccga tagagtatat aacatccgtc atgtcgcccc attgtatgtt
     6421 ttttggagcc atcagaagat tcactaacaa agaaacaatg aatatattaa caacactcgt
     6481 aatgatgagc aaaatcatcg cagcaatttt tgcaacatac aaccgtgagc gcgaagacgt
     6541 atgcagaaac agttgtttca gagtaccata ttgatactca tccgtccaaa taagaggtga
     6601 caaaacaatc gcccaaggta gaataacaag cattcccgat aggccaagca aagcatttac
     6661 catttgagcc accgtatcat cagccttgag attactggtg tatgcccaag agaacagtac
     6721 cgtcatcaca ataaaaccaa tgtgtgaaag aataaagatt cttttattta ctatcttcaa
     6781 acattcattc cataacaatt taacccacct caccgcgcgc agttgtccat tttaaaaact
     6841 tatcctctaa actcgtatgt gccgacaaca cccgatgaac ttccaccccg gcatcacaca
     6901 atgctcgaat cagctttgga acttgacctt catcaatagc tactgtcata gtatgcaaac
     6961 cgttagataa tttctgtgtc tgcatataat ccaatgcatg ataatcatcc ccaaacaagt
     7021 taaccacaac ttcgcttgta agctcaacat tatcaatgtg gagagtgata cagaattttc
     7081 catcatttaa cccatcatca atccgctgct ctgtcactaa gcagccattc tgcataataa
     7141 ccactcggcg tgccatctgc tcaatctcag acagttgatg actggaaatc acaattgcta
     7201 cgcccaaatc tgccgcaatt ctatttaaat agttccgggt ttcacggaca ccagaaggat
     7261 caagtgcatt cataggctca tctaacacaa gcaactttgg ctttcgcagt agtgcttgtg
     7321 caattcccaa gcgttgtttc attcccatgg agtacgtgcc tactcgctgc ttaagcgcat
     7381 gttctatacc agttagactg gctacctcca gcaaccaatc cttactcgca tttttgtgca
     7441 aacgctgata ttgacgtaaa ttttcgtatc cactcaaata aggatagaat gcaggtgctt
     7501 caatcactgc ccctacattt aagagtgctt tagaaaactg actcttaata ctgtaacctg
     7561 caatctgcac gtccccggaa cttattgtgc ttagaccaac tatcatcttc atagtggttg
     7621 tcttgcccgc tccgttcgca ccaagtagtc caataatctc tccctctacc acatcgaatg
     7681 atatgtcttg cacaatcaac ttgcccttaa tttctttcgt taggtgttgc accgatagta
     7741 ccgttttcaa ttgtcccact ccttacaata taagtacagc ctcatttcat gaattcatta
     7801 agaacagcct gtaaagaaaa atcagctatg aactcatttc tttatagtaa tattgataat
     7861 aatttgaagt atgtaacaac tgactgtgat ttcctacatc gcaaaccttc ccattctcca
     7921 aaacaatgat catgtcgcta ttcatcaccg tcgataaccg atgggctatc actattcgtg
     7981 tgcaattaat actagataaa tattcatcta cccgcgcttc acttatatga tccaaagcgc
     8041 tcgttgcttc atccaatact agtacggttg gattattaag tagtgccctg gccaaagcta
     8101 ttcgttgtct ttgccctcct gaaatattcc tgcccatttc agccaaaact gtctgatatt
     8161 tcatcggcat cgccataatt tcatcgtgaa tattcgctgc ttttgccacc cgcactactt
     8221 catccatagt tacaccatcc tggtgcagga caatgttatc ataaatacta cgattgagta
     8281 atgatatatc ctgtggcact attcccatct gtttacgcac atattgcata tccaaatccg
     8341 aggtttcatg attatcatag tatatttccc ccgaggttgg tgtaaataac ccaatcatca
     8401 aatgagctaa agtcgatttc ccagaaccag attgtccaat aatggctatc ttttgcccta
     8461 gctttatatg taaagaaatg tcgtttatca ccttcggact atacttcgaa taggagaagc
     8521 tgacatgtga tagtctaata tctcctctta cttttacttg caatttacct tcattctgct
     8581 caattggaga ttccagcacg tcatgtgttc ttttcagaat agtagtcgta agaatatatg
     8641 agtttatcgt attcataaga cttgatgatg tagtgaaaag tagcgtcgca attgcttgaa
     8701 atgagacaag ctcaccaacc gtcatagaac tgtatttacc agtaactaac agaacgccga
     8761 tacttagcac aatgagtggt gacataaact gcaatccatt gctagttgtt gtaatgtagc
     8821 tattcaaatt ttccttacgg cggtacaccc gcaataaatg cttgaattta ttaagccatt
     8881 gggagtaaac ttgctgttct gtccctgata tttttactcc cataataccg tacaacatct
     8941 ctgtctgcac agcttgcacc tctgtcgttg ccaccacttg ttgctgatta atctctgcta
     9001 catagcgttt agtgaaaatg accaacaaaa tatttatgct taccagcaaa aatacaacca
     9061 tcgcaagcaa tggagatatg aacaacatat aaccagataa tacaaataac atgaagccat
     9121 ccaatatacc tgtaatcaga gtgcctgaga gctgatttcg gattgtggcc aagctattca
     9181 ttcgaaaaag catgtcccca tacgaacgta ataagaagaa cggtaaaggc aacttcaata
     9241 aatgtgagaa aaagcttgtc tgcatctcat aatccaaagc attgtgcaat cgaaccaaaa
     9301 cacgactacg cgcgaatgta attaacatgt atgcaagtag aaagctgatt atagatataa
     9361 aaaccgttat agataaactc gaatttttcg gaatcataat ttcgtcaata acatgtttca
     9421 tgaataacgg catacctact attatgactt gcaaagccag tgtaataaga aaaacatata
     9481 cgaacagatt tttatgtgat tttacataga ctaaagaatt taaccaaaca ttctgatctt
     9541 tctcaacgtc gagtcgttct gttaaatcca ctgtcatcaa aaatccagta aattgctcgc
     9601 tgaagctctt taatgacagc ttgattcttc caaaacgtgg gtcaacaata cgagcataat
     9661 tgttatctat cttttcaaga actacaaaat gatcttggtt ccaatgtaga attgctggta
     9721 aagaaacctg ctttaattga tcaatatgtt caattcgata agctttaaca ccaaagccta
     9781 ggctctcagc aattctcttt aattgcaata gtgttgtacc atcccgtcca acgtccgccc
     9841 tttcacgtag tctagataat gaaacctcct tttgatagta ggctgatatc atagcaaggc
     9901 aacaaagtcc acattccgac tgatgcatct gctcgacata cggtatacgc cgacgagcca
     9961 ttacattctc tcccttctac attatttatg atcacacaat ttatccagaa atagaagaga
    10021 agaatttatc attctccaag tttaaaatgt taggaacttc ttccggaaat gcctgcttta
    10081 atagaccaaa tccaataccc gacaggccac ccattaatcc tttaatatca aaagcgcgat
    10141 ggacccccgt gttattccat ggttggtcat ttagaagtct gagcagatac gctctgacta
    10201 cattgatagt atcctcatta cgatcaagaa ctgaattagc ataaagtaat atttctaatt
    10261 gtccaaaatc gccgtgacaa taaacaggtt ctgtcccaaa acctaattta agagttgttt
    10321 caagagcaat attaatttct tgatcaatat gtacgtccca atatccattt tccaacaatc
    10381 gtagtcgaga taataatatc cccggcgcac catgacacca agtaaccctt gcagtatcat
    10441 taggagtaac ccaatttttc aattcagcac aatagtttgc acgctcatac tgtaatccct
    10501 tttcaatata ttcaatgtac tctgcacgtt gagttaccct gtataacgat gataatgaag
    10561 caataattcc agatacgccg tgagaatacc ccacatagag cttacgattc ggtgtcgtaa
    10621 accaagccat actaccatct ggcaatgttt gtgcattctg aagcaaatgc tccgcacatt
    10681 tctccgcacc ttgcaacgcc tctgtccaac ccgttccatg atatatatgt aaaagtacat
    10741 caatagctcc agctgcacca cctatataat cgaatgcggt gtctttatca acgagttcac
    10801 aataataagg aaggtattct ttaacagttt gtagtaactc ttcatcattc cataagcgtg
    10861 acaactgata agtagcaaat acgccaccac cgatgctacc aacttcaaat gctccaatgt
    10921 ttaacgatac agcatttgat ctgcacttat ccctcataat ttctaacaac ggctgcaatg
    10981 cttttcgagc catattttta tattggttat ttgcagtcag ttcagataaa taacccaaaa
    11041 acaaagcaat tccactattc ccattataaa ggtcatttcc tactggaatt agtctcagtt
    11101 ttctctcatc atcgccactg gctactaaac caatccatgt tatatcatca gctgcattat
    11161 tcgaaggtat aattgccgat tgaaccaaac tttctccaat tgaagtagct aatcggacat
    11221 actcggcttt ccaattagac cctagcacat cgtttgaatc ttttaattga atttcaggaa
    11281 tacgatagga ataaaggtca ggcttagatg ctaaaacaga catatttagt aattgcaact
    11341 gttcttttaa gtccttttcg cccattttat cgattttgtt tattacaatg tctatacctg
    11401 attgctcaaa taactgcgga attcgttcac cattagatgc ccaagcatct ctttcagacg
    11461 gacaggtgta aaagataggg atatccccgt cttcaatatc gcgcatctcg tagggaacaa
    11521 attttaaatg tttaggatca gctaagcatt gcaaccataa tcgatgcaaa acaactttac
    11581 gatctaattc gtctcgcaat aaatcaggat gatatagcgt acgcattagt tcaccatatg
    11641 ctctagtatt tcgcactatc actctaactc taacgtcatc aaactctcga atcatttctt
    11701 tcagtctgtg cttattctcc atcataatcc tgtatgcttg agcaaaaccc tgttcaatgt
    11761 cattaatata tcgataacta tctacaactt cgttattata atgtggaaga ttatgagttt
    11821 ttcctgattc ccccatactt ctttctaacc tcattcgatc cgttcctctg tcaacgagac
    11881 tcactgcatt cggtactttt tttccaccgg atccaaaaat accgctaata tcaaaacctg
    11941 agtacgtctc tgagttataa atatactgtg gtaacatgcc agaagacata acagaataat
    12001 atagaatttc ataggcatga ccattggcgt catgttcaaa tttcttcgta cttatatgac
    12061 gatgaaataa agattctaga tcaattacaa cagggctaga tccatgcgca ataatattct
    12121 cataatggaa gtccgtagcg ttaaacatgt acatcatagc caagtttacg cccatatttt
    12181 tatagaattc actaatttct tcaagggatt tgcactcaga aaactccaca aactctgtcc
    12241 aaccgtaact tccacaatct atattttcta ttattttcat atacggaaca ccaaactgtc
    12301 gcatccacga caggattcga taatatcctt tatcaacctt tagtgaacgg ggtttatata
    12361 ccaatttgca tcctgttgta aactctaaaa tcgttacact tcgtccatcg tgagtatcgc
    12421 ctgcaccaat atgtagccga acaagcttgc caaactgctt gacctcaggc atatgtgaaa
    12481 caattttcga atagtcagcc gtgaacctat ttaacacttc actaacatgg actgcccatt
    12541 tttcagttat acgaagcaat gaacgaatta actcagggta ttcattggcc aattgtctta
    12601 aatactcttt gtcatgtagc aaattttcaa agtactggta tctcttttct gaagtttctc
    12661 cttgtagaag tccctgatca ctcaatacat ttaattccaa tattaaagtt ttgtaactaa
    12721 aatctatgat tctttgaaat aaagaaggta gcagactttt aaaaaaagat ttacctgtat
    12781 gtaaaatatg agaatctaaa ccacgaattg ttccctgctt ttccaataaa tcaatagcca
    12841 gtaataaaaa acgttcaacg aatcccgaaa atacgggcgg agtagtagaa aagtagtctt
    12901 ccactgagcc tttcaacaac tcttcccact gatatttcca tgttaaatca tttttctgca
    12961 aatttataat ggtcccaact tctagattgg acacctcttt gaggctcttt tccaaatact
    13021 cttctttatc atagaaaaat tttgaccaat attttaactt ttcactagta tttatcacta
    13081 tataaaacaa cctttcaatt taggtataca tccgagatac gtgtaaaaat aggtcataga
    13141 cttacttttt atttctagag gcgatttagt gagcttataa atattgtttc gtctattttt
    13201 attaaagaat ttgtctatta tgggttaacc ttaatcatcc attagttagc tactgaaaac
    13261 acttcgtttc aattttataa aaataagttc aaaatttata gagaaaatct tgattttaag
    13321 tcagtttgaa aatataatta aggttatgac tcaaaattac atgtatctcg gctgtatccc
    13381 aatttagaag cagataattg acacaactac atggagaaag gagggcattt caagctatat
    13441 actcagcaag caccatttac aatgcttcga taatattagc agaatgccct ccgatagaat
    13501 ccatgtcaaa cctaaacgga tcaccactcc gttactactg tgaattaact tgctctagaa
    13561 taaagtaagg tatcccgtaa gattacacta acatccccat atccaaggcg tacaatcagc
    13621 cgtaatggaa actagacaat taccatccgt aaagcctagc gcttgagcac caccagctac
    13681 tgtatccatc tcagtatctg tcaattcaga taatacacta cctacaggat tatatgtagc
    13741 tgcattaaga ttttccattt gatttttcca ttgcatagtt atcacctcct tgttactact
    13801 gtgaatcaac ttgctctaga ataaagtaag g
//
