LOCUS       c00033_gnlPro..        13773 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FLKJMJPB_37.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 21:54:28
            Original ID  :: gnl|Prokka|FLKJMJPB_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 24111
            Orig. end    :: 37884
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13773
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[34111:36495]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12384
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13773
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13773
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             36..212
                     /locus_tag="ctg33_24"
                     /transl_table=11
                     /translation="MTVWLFRAGKQGEFENKFLEDGRVYLTWDDLNINLKEITSKEDLY
                     KRLIEHYDLKRWP"
     CDS             complement(381..1478)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sugar_tr"
                     /gene_functions="transport (smcogs) SMCOG1007:sugar and
                     other transporter (Score: 55.5; E-value: 1.6e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg33_25"
                     /sec_met_domain="Sugar_tr (E-value: 9.8e-18, bitscore:
                     55.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTGTAAGLLTLSVAIMALGSLVIACTPGYSRIGVLSPVILVLAR
                     LVQGISLGGEYGTSATYLSEMASSGRRGFYSSFQYVTLVSGQLIALGVQIVLQLALNES
                     EMTSWGWRIPFVIGAIGALVVLWLRRTMDESEQFEEMGSETRKNAGTLKVLLNYPKAVL
                     TVVGLTLGGTVAFYTFTTYLQKFMVNTSGIDKETVSWINFIALFIFVVFQPLAGKLSDR
                     IGRRPLLIGFGILGTLLTVPIFLWLRETQNPVFAFLLMMAGLIIVTGYTSINAIVKAEL
                     FPTEIRALGVGFPYSLTVAIFGGTAEFIALWLKNAGVESAFFYYVAGCIAISLLTYLFM
                     AESSKHSRIEAELQSRPDSKNKIIT"
     CDS             1953..3563
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_26"
                     /sec_met_domain="DAO (E-value: 9.1e-11, bitscore: 33.2,
                     seeds: 522, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILRLVKRFPGDCLVLKKRQCVRNNISKYRDKEKVIMSIRQGKTD
                     VILIGAGIMSATLGTLLKELTPDWEITVYEKLAKPGEESSNEWNNAGTGHSALCELNYT
                     PEKPDGSIDITKAVNVNEQFQLSRQFWSYLVSKGLIRNPQDFIRPIPHMSFVEGEENVA
                     FLKKRFKALSAHPLFEGMAFSDDPGQLKEWIPLVMEGRKSNEPVAATKSDAGTDVNFGA
                     LTRMLFDHLQRQNVEINYKHAVQDIKRTPEGNWEVKVHDIEHNRIEYHTAKFIFIGAGG
                     GSLPLLQKTGIPESKHIGGFPVSGLFMVCNNPEVTSRHHAKVYGKAKVGAPPMSVPHLD
                     TRYIDHKKCLLFGPFAGFSPKFLKTGSNLDLIGSVKPNNVVTMLASGAKNVPLVKYLIG
                     QLLLSDEKRLETLQEFIPDARLEDWDVVVAGQRVQVIKDTEAGGKGTLQFGTEVVTAAD
                     GSVAALLGASPGASTAVHVMLEVIEKCFPDRKKAWAPKIKEMIPSYGVRLAENPDLLHQ
                     IHAETAETLGLTEKEPAYR"
     CDS             4069..4728
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 61.7; E-value: 2.5e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg33_27"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-19, bitscore:
                     61.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWTVVQNSLPMFEKGFWLTLRLSFFGIIGAGVLGLICSFIQYFK
                     VPVLRKLVSAYVELSRNTPLLIQLFFLFYGLPQVGIKFSAEVCGIIGIIFLGGSYMAEG
                     FSGGLAGVSKTQIESGLAIGLSRFQLARYVIFPQGLMLSVPAFAANVIFLIKETSIFTV
                     LAIPELTNTALDLIGMYYNTNEYLFMLVVAYAIILIPLSILLTWLEKKVRYGTFGN"
     CDS             4832..5398
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 61.2; E-value: 3.7e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg33_28"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.3e-19, bitscore:
                     61.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLGVLRTLHNPLLRLLLRLYLEFFRIVPTIVLLFLFYYILPQSFN
                     INYKADTVGTIVFSLWMAAEMSDIVRGALISVPRHQVESGKAVGLSTVQLYRYVLLPQS
                     VHLMIPATINLMTRIIKTTSLLLLISVVDVINVGQQIIEANSHRYQDGAFWIYGFIFIL
                     YFILCYPLSRLARQLERRGKAGANG"
     CDS             5391..6128
                     /locus_tag="ctg33_29"
                     /transl_table=11
                     /translation="MAEPLLKVEHLKKSYGEKQVLEDISFEVEEGSVVVLLGPSGSGKS
                     TLIRCLNGLEAFQGGTILFNGETVRPSPKNWRRLRQQIGMVFQSYDLFPNMTVLENILL
                     GAVKVQKRKKDEAARQAMGLLKEVGMEQYANAYPRQLSGGQKQRVAIVRALELNPKLML
                     FDEVTASLDPEMVRGVLEIILRLAREKMTMIVVTHEMNFARKIGDKILFLEDGKILEET
                     PGRQFFTKPQTERAKNFLESMDF"
     CDS             6156..6998
                     /locus_tag="ctg33_30"
                     /transl_table=11
                     /translation="MKKHRLFGLVSAFLLILSLALAGCGKSSGNSSSSNPSSVSAIKKN
                     GTIKIAVFGDLPPYGWVDKNGQRQGYDVALAKQVAKDLGVKVKFVQVNANNRVDALKSN
                     KVDLVLANFTVTPERKQVVDFAKPYMKVSIGVVSPKKKPVTSVSQLKGKSLIVNKGTTA
                     ENYFTSKQKDVKLQKYDSKTEQFNALKNGRAVALADDNSYLYAWVKNHPDYTVGIKTLG
                     PNQYIAPAVKKGNQSLLNWMNKEITKLNNNGFFKSDYNKNLAPYFGSDIRAEDIIITK"
     CDS             complement(7036..8196)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_31"
                     /sec_met_domain="Ala_racemase_N (E-value: 1.8e-30,
                     bitscore: 97.5, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLPRVEINLEKIRHNAKTLKQLFGRKGISITGVVKGVAADLKI
                     AGTLVDAGIKSLADSKIANIEKMRKAGIKADLILLRAPGISEAEKTVRFADISMNTELD
                     TIRALSAEAVRQQKTHKIILMVEMGDLREGILLKDAPAVIREILTCPGIELAGIGTNFA
                     CFGGVLPTEQKMQAFSRFVHAMQELFSLKLPYVSGGNSANYNWAVKTKDAGAVNNVRLG
                     ESILLGRETSGGHTIPSLYQDAFCFVAEVIESKIKPSVPYGTIGKNAFGEQVTFIDRGN
                     RRRTIVSAGRHDVLVSGLTPVRPFHIIGSSSDHIILDTQNAVLVPGDEVRFYMDYGAML
                     RAMTSPYVYKTYVHGAATTEPYKQQFLLLRGTKQSRPAETEKSPAN"
     CDS             complement(8196..9272)
                     /locus_tag="ctg33_32"
                     /transl_table=11
                     /translation="MKKRAIVYCENQFGTTDGKTANGLIREPGNYTITAVIDSSKHGQD
                     AGMLLDNKWSGIPVCKDLEDALSHSGPKPDDFIFGIAPANAFLKPEERKVILQAMEAGL
                     NIINPLQEFLTDDEEMAAHAKACGVTIRDIRKPRPKKEWTLFTGEILKMNTPVVAVLGT
                     DGACGKRTTAKCIEKAFMEKGYRPAFIATGQTGLIQGAKYGFAMDAFPLQYLIGELERE
                     ILRANKQEHPDIIIVEGQGALSHPAYASSTGILKGARPQAVILQHAPKRKYLSDFPFAE
                     VPKVEDEISLIEHFGKTKVIGITLNHDGMADSELEDTIRRYEETYHLPVTDVLKTGTDK
                     IINALIDFFPSLKKAVVS"
     CDS             9367..9585
                     /locus_tag="ctg33_33"
                     /transl_table=11
                     /translation="LRMGMPETPGYWKLPNIIITMLWKKGKPEACNQDSKGGHSAASPA
                     LEKPPCVWKRRARDSVSYPALIPAGFF"
     CDS             complement(9660..9830)
                     /locus_tag="ctg33_34"
                     /transl_table=11
                     /translation="VLDAIKEWENLSANRENKVLYEARLKFYATSSRISAVKERKGSEK
                     GFKKELKKGYK"
     CDS             complement(9834..10004)
                     /locus_tag="ctg33_35"
                     /transl_table=11
                     /translation="VNTCITRAKWKQYRRGRKAKPPAAYPWLMMLSAADYRKKTVNTDI
                     LQELEEWAMNG"
     CDS             complement(10001..11128)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_36"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.2e-14,
                     bitscore: 45.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFEELPTPCYVVDEQKLEDNLKILNGVMKRTGCKIVLAQKAFSM
                     FALYPLIGKYLSGTTASGLYEARLGHEEMGKENHIFSAAYREDEIDEIVSICDHVIFNS
                     FSQLEKFKGRVIAGGKKAGLRINPECSTQTGHAIYDPCSPGSRFGVTQEQFRPDLLDGV
                     TGLHFHTLCQQNADDLETTLNAVEEKFGEWLPQMEWINFGGGHHITREGYDIPLLEKCI
                     KRMQDKYGLEVYLEPGEAVALNAGYLVTTVLDTVKNGMDIAILDTSASCHMPDVLEMPY
                     RPPLIGAGEPGEKPYTYRLGGQTCLAGDTIGDYSFDKPLKEGVRLVFGDMAIYTMVKNT
                     TFNGMPLPAIAIQYKNGDCAIVREFGYHDFKMRLG"
     CDS             complement(11128..12384)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_37"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.6e-44, bitscore:
                     144.2, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 4.6e-40,
                     bitscore: 128.3, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIALAFYYAKILFEGDRRMGKALIIGAGGVASVAAHKCVQNSEV
                     FEEICIASRTKSKCDALKAKLDGGKTKVTTAQVDANHVDELVALIEKVKPDVVMNLALP
                     YQDLTIMEACLQTKTNYLDTANYEPEDTAKFEYKWQWAYRERFEEAGITALLGSGFDPG
                     VTGVFSAYALKHHFDEINYIDILDCNAGDHGYPFATNFNPEINIREVSANGSYWENGKW
                     IETKPMEIKRVYDFPEIGERDMYLLHHEELESLAANIPGIKRIRFFMTFGESYLTHLKC
                     LENVGMTSIEPIEFEGKQIVPLQFLKAVLPDPASLGPRTKGKTNIGCIFRGKKDGKDKT
                     YYLYNVCDHEACYKEVGSQAVSYTTGVPAMIGAMMLIQGKWDRKGVYNVEEFDPDPFME
                     ALNKWGLPWKESYNPELVD"
     CDS             complement(12802..12900)
                     /locus_tag="ctg33_38"
                     /transl_table=11
                     /translation="MMAFFQPSGHTVLENRDPGRSPPLKRSRPDMV"
     CDS             complement(12897..13703)
                     /locus_tag="ctg33_39"
                     /transl_table=11
                     /translation="LHQFFLEKTWQLTEDWYASLDKSTVQGVYASTDPEVVAKLKEQNH
                     EFHVQFCEVFLKDEDTFLHHFEKWVMNVAQDEEHLSTPNHFILREFFHTQEQYLDLFDS
                     FVAAHEGKYTYEELNFWRRAIIRTFEHVMLRFMKENHHYSLKRLESQQEMIKELSSPVI
                     MVGKNTALLPLVGEIDSNRAKIILEKTLEQCAEKSVLLLYIDLSGVVVIDTMVAQQIFR
                     LIETLRLIGVKCILSGIRPEVAQTAIQLGIDFNDVTIHSKLELMPE"
ORIGIN
        1 aattattatg ctacgtcaaa gaaaggagtt acataatgac tgtttggtta tttcgtgcag
       61 gaaaacaagg ggagttcgaa aacaaatttt tagaagatgg aagggtatat cttacttggg
      121 atgatttaaa tattaatcta aaagagatta cttccaaaga ggatttatat aaacgactaa
      181 tcgaacacta tgatttaaag cgatggccat aatgccggtg caccaggcaa gcgcggtcca
      241 aatatcatcc ttcattcagg agggcccgaa tcgtattcac gattgaattt acgggctggt
      301 ttttgggtat tcccggtctt tcatcttgca aggaaaaata aaacagctgc agcctgccac
      361 gctgcagctg tttggcattt tcaggtgata attttgtttt tcgaatccgg gcgggattga
      421 agttctgctt cgatccggga atgcttcgag gattcggcca tgaataaata agtgagcagg
      481 ctgatggcaa tacagccggc aacgtagtag aaaaaggcgg attccacgcc ggcatttttc
      541 agccaaagcg cgataaactc ggctgttccg ccaaagattg cgacagttaa tgaataggga
      601 aacccgacac caagcgcgcg gatttcagtc gggaacagct cagcttttac aatggcatta
      661 atggaagtat agccggttac aatgatcagc cctgccatca tgagaagaaa agcaaaaacc
      721 gggttctgcg tttctctcaa ccataaaaat atcggtacgg tcaaaagggt cccgagaatg
      781 ccgaagccga ttaacagcgg cctgcgcccg atccggtcgg acagctttcc ggcaagcggc
      841 tggaaaacaa caaagatgaa aagggcaata aagttgatcc agctgacggt ttctttatca
      901 attccggacg tgttcaccat aaatttttgc agataggtgg tgaatgtgta gaatgcgaca
      961 gtgccgccaa gtgtaaggcc gacaacggtc agcaccgctt tcggataatt caataggacc
     1021 ttcagcgttc cggcattttt ccgcgtttcc gatcccatct cctcgaattg ttcggactcg
     1081 tccatcgtac ggcgcagcca caagaccacc aatgcgccaa tcgcgccgat cacaaacggg
     1141 atccgccatc cccacgaggt catttcgctt tcatttaatg cgagttggag cacaatttgg
     1201 acaccaagtg cgatcaactg ccccgataca agcgtgacat attggaaact ggaatagaag
     1261 ccgcggcggc cgctgcttgc catttcggac aaataggtag cagaagtgcc gtattccccg
     1321 cccagcgaga tcccctgcac aagccgggcc aggaccaaaa taaccggtga cagcacacca
     1381 atcctgctgt atcccggtgt acaggcaatg acaagcgaac cgagcgccat aatggcaacg
     1441 gaaagggtca gtagccctgc ggccgtaccg gtctgcatac cggcccatga tcaggctccc
     1501 gagcggccgc atcagaaaac caatagcaaa aatcccggct gtattcaata actggacagt
     1561 ttggttcccc tccggaaaaa actctgatga aaaataaacc gcaaacgcag aataaacata
     1621 ccaatcatac cattcgatca gattgccaag tgatccttta aagatgttag cagtcacatg
     1681 tctggatgtg cgtccggttg tttgtgccaa tttgtcttcc ccctttgtaa aatgaaaatt
     1741 cccgtcttca atccgtgaaa aatatctcct ggcatccccc ttttggcaaa tgaaagaaat
     1801 ataccagtaa aatttctatt tacaagattc attatattat atttttaggc aaaatgaaga
     1861 atgaatcatt cagcaaataa aaaggtttcc tgatatttcc attgtcaaat tgtgtatcat
     1921 tattctaaag aattatcata aaatatgata ttatgatatt aagacttgta aaacgttttc
     1981 ccggggactg ccttgttctg aaaaagaggc agtgtgtccg gaataatatt agcaaatata
     2041 gggataagga gaaggtaatc atgagcatca gacagggaaa gacagacgtc atcttaattg
     2101 gtgccggcat tatgagcgca acgctgggca ccttgctgaa agaactgact ccggattggg
     2161 aaatcaccgt atatgagaag ctggcaaaac caggggaaga aagttcgaat gaatggaaca
     2221 atgcggggac cgggcactcg gcattatgtg agctgaatta tacgcctgaa aaaccggacg
     2281 gctcaataga cattacaaaa gctgtaaatg taaatgaaca attccagctt tcaaggcagt
     2341 tctggtccta cctggtcagc aaggggctga tccgcaatcc gcaggacttt atccggccga
     2401 tcccgcatat gagctttgta gaaggggagg agaacgttgc ttttctaaaa aagcgattta
     2461 aagcgctgtc agcccatccg ctttttgaag gaatggcgtt ttccgacgat cccgggcaat
     2521 taaaggaatg gattccgctt gtgatggaag gcaggaagtc caatgaaccg gttgcggcga
     2581 caaaaagcga tgcagggacg gacgtcaact ttggtgcctt gacccgcatg ctgtttgatc
     2641 atttgcaacg ccaaaatgtc gaaatcaact acaagcatgc cgttcaggat attaaacgca
     2701 ccccagaagg aaactgggaa gtgaaagtgc atgatattga gcacaacagg atcgaatacc
     2761 atacggcgaa atttattttt atcggtgccg gtggcggaag cttgccgttg ctccaaaaaa
     2821 ccggcattcc ggagtccaaa catattggag ggtttccggt aagcgggtta tttatggtgt
     2881 gcaacaatcc tgaagtcacc agccgccacc atgcaaaagt gtacggcaaa gcgaaagtcg
     2941 gcgcgccgcc gatgtccgtg ccgcatttgg atacaagata tattgaccat aaaaagtgtt
     3001 tgctgttcgg cccgtttgcc ggcttctcgc cgaagttttt aaaaacaggg tcaaatttag
     3061 acctgattgg ttctgtgaag ccgaataatg tcgtaacgat gcttgcgtcc ggggcaaaaa
     3121 atgtaccgct tgttaaatat ttgatcgggc agcttctatt gtcagacgaa aaacgcctgg
     3181 agacactgca ggaattcatt ccggatgcga gattggaaga ctgggatgtt gtcgtagccg
     3241 ggcagcgtgt ccaggtgatt aaagatacgg aagcaggcgg aaaaggcacg ctccagttcg
     3301 gtacagaggt ggtaacagct gctgacggtt cagtcgcggc attgctcggc gcttcgccgg
     3361 gtgcttctac tgctgtccat gttatgctcg aagtcattga aaaatgcttc ccggaccgga
     3421 aaaaagcatg ggcaccaaaa ataaaagaaa tgattccttc ttatggcgtg cggctcgcag
     3481 aaaacccgga tctgctgcat caaattcacg ctgaaacggc agagacgctc ggcctgacgg
     3541 aaaaagaacc ggcctaccgg taacgcgtgg agcgctaaaa tgaagggcct ttgatcctaa
     3601 agcggattga aggccttttt ttggctgtaa cgcgtcttaa ccggcattca ttttgcaggc
     3661 agccggaaag cagtacgggt gcaagcggag gaacaacttt ggcatgctgt tttttttggg
     3721 tgctatgcaa agaaaaccct atcaagtcga taggaatata ttgatttttg tcccggcgtt
     3781 cagtaaaata aagatgttgc taaaatgctg aaaatttctt atcccgggcg gcggaagggc
     3841 tgtccttgga aaccggcatc ataatagtac agttcatgat cgtctatcaa gataagaaaa
     3901 ctgcagcaat acctgaaaaa ggacagtcgt tttcttagga aacggctttt tgtcgtccgg
     3961 cctttaaacg cgcaagcacc tgattcggga cagcaacgcc atacataccg gacggctggc
     4021 gcaagcccgc ctggattgaa gagaattttc caaaatagga ggggtgagat ggactggacc
     4081 gttgtgcaaa acagcttgcc catgtttgaa aaaggattct ggctcacttt gcggctttcc
     4141 tttttcggca ttatcggggc tggtgttctt ggcttgatat gcagttttat ccagtatttt
     4201 aaggtgccgg ttttacggaa gcttgtatcg gcctatgtgg aactgtcccg caatacgcct
     4261 ttattgatcc agttattttt ccttttttac gggcttccgc aagtcgggat caaattttct
     4321 gccgaggttt gcgggattat cgggattatt tttcttggcg gcagttatat ggcagaaggg
     4381 ttttccggag ggcttgcagg cgtttcgaaa acgcagattg aatccgggct tgcgatcggt
     4441 ctgagcaggt tccagctggc acgctacgtc atctttccgc agggattgat gctcagtgtc
     4501 ccggcattcg ccgcaaatgt cattttttta atcaaggaaa cctctatctt taccgtgttg
     4561 gcgattccgg aactgaccaa cacggcactt gacttgatcg ggatgtatta caacacgaat
     4621 gagtatctgt ttatgctcgt tgtggcttat gccatcattt taattccatt gtccatcttg
     4681 ctgacatggc tggagaagaa ggtgcgttat gggacatttg ggaattaata tcttttttga
     4741 aggagccaac tttttacgtt tactgggtgg attatacgta tcggcaaaaa ttgcttttct
     4801 gtccatcgtt ttcggcggta tcctcggcat cgtgctgggg gttttaagga cattgcacaa
     4861 tccgttgctc cgccttttac tcaggctgta tttggagttt tttcgcatcg tgccgacgat
     4921 tgtcctgtta tttttgtttt actatattct gccgcaaagc tttaacatca actataaggc
     4981 ggatacggtc gggacgattg tcttcagcct gtggatggct gccgaaatga gcgatattgt
     5041 ccgtggtgcg ctgatttctg tcccaaggca tcaggtggaa tccggaaaag cggtcggttt
     5101 aagcacggtt cagctttacc ggtacgtgct gctgccgcaa tcggtccact taatgattcc
     5161 ggcgaccatt aacctgatga ccagaataat taagacgact tcccttttgc tattgatcag
     5221 cgtagtggat gtcatcaatg tcggccagca aatcatcgaa gcgaatagcc accgctatca
     5281 ggatggcgcg ttttggatat acggttttat atttatcctg tatttcattt tatgctatcc
     5341 gctttcccgg ctggcaaggc agttagaaag gaggggcaaa gcaggggcta atggctgaac
     5401 ctttactgaa agtcgaacat ttaaaaaaat cgtacggcga aaaacaagtg ctggaggata
     5461 tctctttcga agtggaggaa ggcagtgttg ttgttctcct cgggccgtcg ggatcgggaa
     5521 aaagtacatt gatccgctgc ttaaacggtc tcgaagcctt ccagggcggc accattctgt
     5581 ttaatgggga aaccgtgcgg ccgtcgccga aaaattggcg caggctcagg cagcagatcg
     5641 gaatggtttt ccagagctat gatctgtttc cgaatatgac ggtgttggaa aacatcctgc
     5701 tcggtgcagt gaaagtccag aaacggaaaa aagacgaagc ggcgcgccag gcaatgggcc
     5761 tgttaaagga agtcggcatg gagcagtatg ccaatgccta tccgcgccag ctttccggcg
     5821 ggcagaaaca gcgggtggcg attgtccgcg cgcttgagct gaacccgaag ctgatgctgt
     5881 ttgatgaagt gaccgcctcg cttgacccgg aaatggtgcg cggcgtgctc gagatcatcc
     5941 tgcggttggc aagagaaaag atgacgatga ttgtcgtcac gcatgaaatg aattttgccc
     6001 ggaaaatcgg ggataaaatc ttgtttttgg aagacgggaa gattctcgaa gaaacccccg
     6061 ggcgccaatt tttcacaaaa ccgcagacag agcgggcgaa aaattttctg gaaagcatgg
     6121 atttttaaaa gaaaaatatt ttggagggtt agaccatgaa gaagcatcgt ttgtttggtt
     6181 tggtttcagc atttttatta attttgtcgc tggcgcttgc aggctgcggc aaaagttccg
     6241 gcaattcttc aagcagcaat ccgtccagtg tttcagccat taagaaaaac ggcacgatca
     6301 aaattgccgt attcggcgat cttccgccat acggatgggt cgataaaaac gggcaacgcc
     6361 agggatatga tgttgcgctc gccaaacaag ttgccaaaga tcttggcgta aaagtgaaat
     6421 tcgtgcaagt gaatgccaac aaccgtgtgg atgcattgaa atcgaataaa gtggatctgg
     6481 ttctggcgaa ttttacagtc acaccggaac ggaagcaagt tgttgatttt gccaagccgt
     6541 acatgaaagt ttccatcggt gtcgtttcac cgaagaaaaa gccggtcaca agtgtcagcc
     6601 aattaaaagg caagtctttg atcgtcaaca agggcaccac tgcggaaaac tattttacaa
     6661 gcaaacaaaa agatgtgaaa ttgcaaaagt acgattccaa aacagaacag ttcaatgcgc
     6721 ttaaaaacgg gcgggccgtt gcactggcgg acgacaattc ctacctatat gcctgggtga
     6781 aaaaccatcc ggattatacg gttggcatta aaacgctcgg gccgaaccaa tatattgccc
     6841 ctgctgtgaa aaaagggaat caatcgctcc tcaattggat gaacaaagaa attacgaagt
     6901 taaacaacaa tggctttttc aaaagtgatt acaacaaaaa tctggcgcca tattttggca
     6961 gtgatatccg tgcggaagac atcattataa cgaagtaaaa aaggcaggct gccgtttttg
     7021 cagcctgcct tttctttaat tggcggggct tttttcggtt tccgcgggcc ggctttgctt
     7081 tgttccgcgc aaaagcagaa actgttgttt gtaaggctcg gttgtggccg caccatggac
     7141 gtacgtttta taaacatacg gagacgtcat ggctctcagc atcgcgccgt agtccatata
     7201 aaatctcacc tcatcgcccg gcacgagaac cgcattttgt gtatccaaaa tgatatggtc
     7261 gctgcttgag ccaatgatat ggaacggccg gacaggggta aggcctgaaa caagcacatc
     7321 atgccgccct gcactgacaa tcgtccgcct tctgttgccc ctgtcgataa aggtgacctg
     7381 ttccccgaat gcatttttgc cgattgtccc atacggcacg gaaggtttga tttttgattc
     7441 gatgacttcg gcaacaaagc aaaaggcatc ctgatataaa gacggaatgg tatgcccgcc
     7501 tgatgtttcg cggcccagca aaatggactc gccgagccgc acattgttta cggccccggc
     7561 gtcttttgtt tttacggccc agttgtagtt ggcggagttg ccgccggaaa cataaggaag
     7621 tttgagggaa aacagctcct gcatggcatg gacaaaccgg gaaaacgcct gcatcttctg
     7681 ttcggtcggg agcacgcctc caaagcaggc aaaatttgtc ccgattccgg ccagttcaat
     7741 cccggggcag gttaatattt ctctgatcac agcaggggca tcttttaata atatgccttc
     7801 cctcaaatct cccatttcca ccatcaggat gattttatgg gttttctgtt gccgcaccgc
     7861 ttcagcggat aatgcgcgga tcgtatccag ctccgtgttc atgctgatat ccgcaaaccg
     7921 gaccgttttt tccgcttcgc tgatcccggg ggcacggagc aaaatcaaat ctgccttgat
     7981 tcccgctttt ctcatttttt cgatatttgc aattttcgag tctgcgaggc ttttgatgcc
     8041 tgcatccacc agggtgccgg caatttttaa atcggctgcg acacctttca caacgcctgt
     8101 aatgctgatt cctttcctcc cgaataattg ttttaatgtt ttcgcattat gccggatctt
     8161 ctccagattg atttccaccc gtggcagaac ggccatcagg aaaccactgc ctttttcagg
     8221 gaagggaaga aatcgatcag ggcgtttatg attttgtctg tgccggtttt taaaacatcc
     8281 gtaaccggaa gatggtaagt ttcttcatag cggcggatgg tgtcttccag ttcgctgtct
     8341 gccattccat catggttgag cgtaatgccg atgacttttg tctttccgaa atgttcaatc
     8401 aggctgattt catcttccac tttcggcact tcggcaaatg gaaaatcgga taaatatttt
     8461 cgtttcgggg cgtgctgtaa aatgactgct tgcggccttg ctccttttaa aatgccggtt
     8521 gagcttgcat atgccgggtg gctgagcgcg ccctggcctt ccacgatgat aatatccggg
     8581 tgttcttgtt tattggcccg caaaatttcg cgctccagtt cgccgattaa atattggagc
     8641 gggaaagcat ccatcgcaaa cccgtacttg gcgccctgga tcaaacctgt ctgcccggtt
     8701 gcgataaatg ccgggcggta gcctttttcc atgaatgcct tttcaatgca tttggcggtt
     8761 gtccgttttc cgcaggcccc gtctgtcccg agcacggcaa cgacaggggt gttcattttc
     8821 aaaatttctc cggtaaacaa agtccattct tttttcggcc gcggtttacg gatatcgcgg
     8881 atcgtgacac cgcaagcctt tgcatgggcc gccatttctt catcatcggt taagaattcc
     8941 tggagcgggt taatgatgtt caatccggct tccattgcct gcaggatgac ttttctttct
     9001 tccggcttta aaaaggcgtt cgccggcgcg atgccgaaaa tgaagtcatc cggtttcggg
     9061 ccggagtggc tgagcgcgtc ttccaggtct ttgcaaaccg gaatgccgct ccatttgttg
     9121 tcgaggagca tgccggcatc ctgcccgtgt ttgctgctgt caatgacggc agtaatggtg
     9181 taattcccgg gttcacggat gagcccgttt gctgttttgc catctgttgt gccaaattgg
     9241 ttttcgcaat acacaattgc ccgctttttc attgctatcc ctccatttat tgaaatttag
     9301 gcaacacaaa aagaacacct agtggcttca aatagtaaaa atactaaaga agatagctgt
     9361 ccgggtttgc gtatgggcat gccggaaacc ccaggttatt ggaagcttcc aaatattatt
     9421 ataacaatgt tgtggaaaaa agggaagccg gaagcatgca accaagatag caaagggggc
     9481 cattccgccg ccagtccggc attggaaaag cccccttgcg tttggaagcg gcgggcgcgc
     9541 gattcagtta gctaccccgc tctaattccc gctgggtttt tttgatttct tcaagcggat
     9601 aatcaagcat atctgcgatc gtttcgggtg aggtgccttt gctcagcatt ttttgattgc
     9661 tatttgtacc ccttcttcaa ttcctttttg aatcccttct ctgagccctt cctctctttc
     9721 accgcggata ttcgcgagct ggtcgcgtaa aatttcagcc gggcttcgta caatactttg
     9781 ttttcccgat tggcactcaa attctcccac tctttgattg cgtcaagcac ttcctaccca
     9841 ttcatcgccc attcctccag ttcctgcaaa atgtccgtgt taaccgtctt tttccggtaa
     9901 tctgcagcag aaagcatcat cagccacgga taggctgccg gcggtttcgc ttttctccct
     9961 cgtctatatt gtttccactt agcccgggta atgcaggtat tcacccgagt ctcattttaa
    10021 agtcgtgata gccgaattca cggacaattg cgcagtcgcc gtttttatat tggatcgcga
    10081 tggccggaag cggcatgcca ttaaaggtgg tatttttcac catggtgtag atggccatat
    10141 cgccaaatac aaggcgaacg ccttctttaa gcggcttatc gaaggaataa tcgccgatcg
    10201 tatcgccggc gaggcatgtc tggccgccaa gccggtacgt atacggtttt tcgcccggct
    10261 ccccggcccc gatgagcggc gggcggtacg gcatttccag cacatccggc atatggcacg
    10321 aggcggacgt atcgaggatc gcgatgtcca tgccgttttt caccgtgtca agcactgtcg
    10381 tgacaagata gccggcattt aaagcaacag cttcgcccgg ctcaaggtag acttccaaac
    10441 cgtacttgtc ctgcatccgc ttgatgcatt tttcgagcaa gggaatgtca tagccttccc
    10501 tcgtaatatg gtggccgccg ccgaaattga tccattccat ttgcggcagc cattccccga
    10561 acttttcttc aacggcattc agcgttgtct ccagatcgtc cgcattttgc tggcagagcg
    10621 tgtggaaatg gaggccggtt acgccgtcca gaagatcagg gcggaactgt tcctgcgtca
    10681 caccgaagcg cgagcccggc gaacaagggt cataaattgc atgcccggtc tgtgtcgagc
    10741 attccggatt gatgcgcagg cccgcctttt tcccgcctgc aatcacgcgg cctttaaatt
    10801 tctcaagctg tgaaaatgaa ttaaaaataa catgatcgca aatcgagacg atctcatcga
    10861 tttcatcttc acggtaagcg gcggaaaaaa tatggttttc tttccccatt tcctcatgcc
    10921 cgaggcgcgc ttcatacaag ccgcttgctg ttgtcccgct caagtatttg ccgatgagcg
    10981 ggtacaaagc aaacatcgaa aaagcttttt gcgccaaaac aattttgcat ccggtccgtt
    11041 tcatcacgcc gtttaaaatt ttcaaattgt cttcgagctt ttgttcatca actacatagc
    11101 aaggcgtcgg cagttcttca aatcgcatca gtcgacaagc tccggattat agctttcttt
    11161 ccacggcagg ccccatttgt tcagagcttc catgaacgga tcaggatcga actcttccac
    11221 attataaacg ccttttctgt cccatttgcc ctggatcagc atcatcgcgc cgatcatcgc
    11281 cggcacgccg gttgtgtacg ataccgcctg cgagccgact tctttgtagc aggcttcatg
    11341 gtcgcacaca ttgtaaaggt aataggtttt gtccttgccg tcttttttgc cgcggaaaat
    11401 gcagccgata ttcgttttcc cttttgtgcg cgggccgagg gaagccggat ccggcagcac
    11461 agctttcaga aattgcagcg gcacgatttg tttaccttca aattcaatcg gctcaattga
    11521 agtcatgccg acgttttcca ggcatttcaa atgtgtcagg taactttcgc caaacgtcat
    11581 gaagaaacgg atccgtttaa tgccagggat atttgcggca agcgactcca gctcttcatg
    11641 gtgcagcagg tacatgtcgc gttcgccgat ttcaggaaaa tcatacacgc gtttgatctc
    11701 catcggtttt gtttcgatcc atttgccgtt ttcccagtag ctgccgttgg cggaaacttc
    11761 gcggatattg atttccgggt tgaagtttgt tgcgaacgga tagccatggt cgccggcatt
    11821 gcagtccaaa atatcaatat aattgatttc atcaaaatgg tgtttcaggg cataagcgga
    11881 aaatacgcct gttacgcccg ggtcaaagcc gctgccgaga agggcggtaa tgccggcttc
    11941 ttcaaaacgt tcgcggtatg cccattgcca tttgtattca aattttgccg tgtcttccgg
    12001 ctcatagttc gcggtgtcga gatagtttgt ttttgtttga aggcaggctt ccatgatggt
    12061 taaatcctgg taaggcagcg ccagattcat gacgacatcc ggtttcactt tttcaattaa
    12121 agcaaccagt tcatcgacgt gattggcatc gacctgtgca gtcgtcactt tcgtttttcc
    12181 gccgtcaagc tttgctttta acgcatcgca ttttgatttc gtgcggcttg cgatgcagat
    12241 ttcttcaaag acttcgctgt tttggacaca tttatgcgca gcgaccgatg ctacgccgcc
    12301 ggccccgata atcaacgctt ttcccattct tctgtctcct tcaaatagaa tttttgcata
    12361 ataaaaagca agtgcaatcc gcatacgtgc gcacaacact tgcttgaaat catcatccta
    12421 aaaaagcatg catatccgca taaacagata tatgcctgcc ataaaagtcc gtggacaata
    12481 tggaagaaag ctttatattc ttataggatc agagtctata tagcaaataa ttacttttac
    12541 cactcttatt gatcgtttca caagttgatg tgcacaagca ccggttgtaa agtaaccaac
    12601 ttataaaatt tgagtttccc actcaatcaa taaggcaacc aaaagttgcc gattcggcat
    12661 ttggcccggc acaccgatgc ctttactcca ctggccaaaa ttatctgctt ggaaagactc
    12721 ctgatgctga atatatgctt tccaaatcat gctcttctat cgtatcagca cggacttaaa
    12781 atagcaagaa gaaaaatttt cttaaaccat atcgggacgg ctgcgtttca aaggggggct
    12841 cctccccgga tctctatttt ccaaaacggt atgcccggat ggctgaaaaa acgccatcat
    12901 tccggcatga gttccagttt tgagtggatc gttacgtcat taaaatcaat gcccaattga
    12961 atggcagttt gcgccacctc cggacggatg ccggaaagaa tgcattttac cccgattaac
    13021 cgcagcgtct caatcagccg gaaaatttgc tgggcgacca tcgtatcgat gacgaccacg
    13081 ccggataaat caatgtacag aaggagaacg cttttttctg cgcattgttc gagtgttttt
    13141 tccagaataa ttttcgcacg gttggaatca atttccccga caagcggcag cagcgcggta
    13201 tttttgccga ccataatgac gggggaactc agctctttaa tcatttcctg ctgggactcc
    13261 aaccgcttta aggaataatg gtggttttct ttcataaacc tgagcatgac atgttcgaat
    13321 gtccggatga tcgcccttct ccaaaaattc agttcctcgt atgtatattt tccctcgtgg
    13381 gctgcaacaa atgaatcaaa cagatcgaga tattgttcct gcgtgtggaa gaactcgcgc
    13441 aaaataaagt ggttcggtgt ggaaagatgc tcttcatcct gtgcaacgtt cattacccac
    13501 ttttcaaaat ggtgtaaaaa tgtatcttca tcttttaaaa acacttcaca aaactggacg
    13561 tggaactcgt ggttttgctc tttcagtttt gcaaccactt cggggtcggt ggacgcataa
    13621 accccctgca cggtgctttt gtcgagcgat gcgtaccagt cttccgtcaa ttgccatgtt
    13681 ttttcaagga aaaattgatg caatgcctgt cttagctcca ttttatcacc cgcatgatgt
    13741 aagatttaac ggttttccga aagaagtctc cca
//
