LOCUS       c00057_gnlPro..        14294 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENGLCLCE_61.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 20:39:49
            Original ID  :: gnl|Prokka|ENGLCLCE_61
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14294
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14294
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1702:4294]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1703..4294
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14294
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14294
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..152
                     /locus_tag="ctg57_1"
                     /transl_table=11
                     /translation="RKAVKLRCLRINLLISPENMRRLAFILLLVPHSFGMGVCLQIWVQ
                     QRLI"
     CDS             complement(549..773)
                     /locus_tag="ctg57_2"
                     /transl_table=11
                     /translation="LKDNDFTHKPLLTKREKEVFELLVQDKTTKEIASELFISEKTVRN
                     HISNAMQKLGVKGRSQAVVELLRMGELKL"
     CDS             complement(1128..1604)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_3"
                     /sec_met_domain="HBT (E-value: 2.3e-17, bitscore: 55.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 7.4e-17, bitscore: 54.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKKHISYIDDWEAWEEGFSFYLPVTVRFSETDMFGHMNNTVPFIY
                     FEQARIEFLQQLGFMGDWAKRGTGSIPVVADLQCDFLQQVFFNDKLRIYVKVSKIGNSS
                     VDLHYMAKNEADEICFTGRGTMVQISAATGKGKPWTAEEKARFADPQAYVSSGN"
     CDS             complement(1703..2470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 100.1; E-value: 2.2e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_4"
                     /sec_met_domain="Fer4_10 (E-value: 2e-11, bitscore: 36.2,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.7e-31, bitscore: 100.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00037, bitscore: 13.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEQKTVTFIIQRQDNPESEPYDETFEVPYRPNMNVISALMEIRR
                     NPVNAKGEKTTPVVWEMNCLEEVCGACSMVINGKPRQACSALVDKLEQPIRLAPMRTFP
                     VVRDLQIDRSRMFDSLKKVKAWIPIDGTYDLGEGPRMPEKKRQWAYELAKCMTCGVCLE
                     ACPNVNSRSNFIGPAPLSQVRLFNAHPTGHMNRDERLEAIMVDGGLANCGNSQNCVQVC
                     PKGIPLTTSIAALNRETTIYMFKKFFGSDHTVD"
     CDS             complement(2543..4294)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 300.3; E-value:
                     8.6e-92)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.1e-91, bitscore:
                     300.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-47, bitscore:
                     153.6, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LANGKIIVVGGGLAGLMATVKIAEAGRQVDLFSLVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMCEAAPGIIHLFDRMGVMFN
                     RTSEGLLDFRRFGGTQHHRTAFAGATTGQQLLYALDEQVRRHEVDGLVTKYEGWEFLGI
                     IKDDEGICRGIVSQNLTTMEIKAFPADAVIMASGGLGIIFGKSTNSMINTGSAASIVYQ
                     QGATYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFHVCVDLKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFVGDDP
                     HKVPMKVFPAVHYSMGGLWVDYKQHTSIPGLFAAGECDYSMHGANRLGANSLLSAIYGG
                     MVAGPEAVNYIDGLEKSANALPSTVFERAVQEQEKKWNDILSLDGTENAYVLHKELGEW
                     MTDNVTVVRYNDRLKKTDEKIQELMERWKNINVVDTSKWSNQAASFTRQLYNMLQLARV
                     ITIGALNRNESRGAHYKPDFPDRNDEEWLKTTMANYDPVNNEPVFSYEDVDVSLIKPRV
                     RDYTKKH"
     CDS             complement(4366..4974)
                     /locus_tag="ctg57_6"
                     /transl_table=11
                     /translation="VAGNREFYNRKLHSLLGVVPIGLFLVIHLTVNHYAVNGAAAFNKA
                     AGFMENLPFLLFVEVVFIYLPLLFHAIYGLYISFTASSNVGTMGYFRNWMYLLQRISGV
                     LVLIFLVFHIYETRIQMALGKELNFDLMANLLANRWMLAWYIIGTVAAIFHFANGLWSF
                     LVSWGITQSRRSQQISTYVMIVVFVLLSVVGVRALLAFA"
     CDS             5403..5861
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="VKSSGGNEQTVAEQLMVPTFGYELLRNILIPDILGKETPDILYWA
                     GKHLARKFQLLTYEEMVSFFKEAGWGTLSIKKEEKYHIEFELSGPMIERQLDMGAGAEP
                     TFKLEAGFLAEQYQMQKKLITEAVEEVAKKAKKIRITVQWDAKDPAEE"
     CDS             complement(5901..7130)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_8"
                     /sec_met_domain="AA_kinase (E-value: 7.8e-58, bitscore:
                     188.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGIIVQKFGGTSVGNVERIRNTVDRIIEEKEKGHDVVVVVSAMGK
                     TTDQLVGLANELSAYPAKREMDMLLSTGEQVTISLVAMALIDRGYDAVSYTGWQAGIIT
                     EPVHGNARITEIRTEKIKSRLAAGQIVVVAGFQGITPEGEIATLGRGGSDTTAVALAAA
                     LHADRCLIYTDVTGVFTSDPRYIPTARKLKAVSYDEMLELASLGAGVLHARAVEFAKNA
                     AVPLIVCSSLEREEGTLIEEEVSVEKNLIVRGVAFEDGITRVTIFGLENGFRNLPDIFT
                     TLAEHHIDVDIIIQNRTADHKTYLSFSIKDKDLKETADLLEAGKEALSIDHFETETGLA
                     KVSIIGSGMVSNPGVAAKMFQVLADHGIAIKMISTSEIKVSTVVDAKEMVRAARCLHEA
                     FELDAVEQNI"
     CDS             complement(7548..9320)
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="LNETIRNKLALLPAQPGCYLMKDRQGTIIYVGKAKILKNRVRSYF
                     SGSHDAKTQRLVSEIEDFEYIVTSSNIEALILEINLIKKHDPKYNIMLKDDKTYPYIKL
                     THERHPRLITTRKVKKDKGKYFGPYPNVQAANETKKLLDRLYPLRKCTNMPDRVCLYYH
                     LGQCLAPCVNEVKEETYKEITDQITRFLNGGYTEIKKELEEKMHEAAEKLEFERAKEYR
                     DQIANIEMTMEKQKITMTDFTDRDIFGYAVDKGWMCVQVFFMRQGKLIERDVSLFPSYD
                     EPEEEFLSYLGQFYAKPEHIKPKEVLITEKADRELAEQLLEIKVLQPKKGQKRELVLMA
                     EKNAKIALKEKFALIERDEERTIKAVENLGEKLGIYTPHRIEAFDNSNIQGTNPVSAMV
                     VFVDGKPAKKEYRKYKIKTVEGPDDYESMREVIRRRYIRALRENLPLPDLIIIDGGKGQ
                     IDAARDVLENELGLEIPLGGLAKDEKHNTSQLLFGNPLEVVPLGRNSQEFYLLQRIQDE
                     VHRFAITFHRELRGKSAFQSALDDIPGIGPKRKKQLLRHFGSLKKMKQAKLEEFVEAGI
                     PRPVSETLIKKLQE"
     CDS             complement(9425..9739)
                     /locus_tag="ctg57_10"
                     /transl_table=11
                     /translation="MAITHATDATFDQEVSQGLVLTDFWATWCGPCKMIAPVLEEIDAE
                     MGDKVKIVKVDVDENQETASKFGIMSIPTLVLMKDGKPVDKVIGYQPKEALQELVNKHL
                     "
     CDS             complement(9925..10905)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 147.9;
                     E-value: 9.8e-46)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg57_11"
                     /sec_met_domain="ETF (E-value: 1.2e-45, bitscore: 147.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 2.5e-38, bitscore:
                     122.4, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKVLVVGEVRDGSLRNVSYETIAAGKTVAEGGEVVGVLIGDAV
                     KDLGKDMIQYGADRVAVVEDEKLKSYSSDGFSQALLAVVESEKPDGILIGHTALGKDLA
                     PKVAAKLDAGLISDATAVESAGEHVVFTRPIYSGKAFEKKIVTDGIIFATIRPNNISPL
                     EKDESRTGDIETVQAEIKDLRTVIKEVVRKVSEGVDLSEAKVIVSGGRGVKSADGFKPL
                     KELADVLGGAVGASRGACDAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEANIFNVADYGIVGDLFEVVPLLTEEIKKLKVTSA"
     CDS             complement(10936..11709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 170.7;
                     E-value: 9.7e-53)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg57_12"
                     /sec_met_domain="ETF (E-value: 1.2e-52, bitscore: 170.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIFVLLKRTFDTEEKIAIANGRIQDDGAEYIINPYDEYAVEEAI
                     QVRDAQGGEVTVVTVGNEDAEKQLRTALAMGVDKAVLINIEDDVEASDQVTTSKVLAAY
                     LKEQEPDLIIGGNVAIDNASGQVGPRVAELLGIPYVTTITNLEIDGGKATVTRDVEGDS
                     EIIETDLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLEEEDVEPKTKTIE
                     VYLPPKKEAGKVLEGEIADQVKELVQLLHAEAKVI"
     CDS             complement(11771..12544)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_13"
                     /sec_met_domain="ECH_1 (E-value: 5.8e-68, bitscore: 221.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFITIKRENAVACIEMNRPPANALAQALLKELAQAFGQLENDPE
                     TRVVLLYGKGRFFSAGADIKEFVQLRESGGSDAIAVSGQELFEKVEAFPKPVIAAIHGA
                     ALGGGLELAMACHIRLVTENAKLGLPELSLGLVPGFAGTQRLPKYIGRGKAFEMLWTSE
                     PLTGTEAVQQGLANHAYKEEELLPKAKALAEKIAKKSPLALKASIELVNYAKTNDYEKG
                     LEQESARFLELFGSKDAEEGIKAFIEKREPRFTGA"
     CDS             complement(12579..13172)
                     /locus_tag="ctg57_14"
                     /transl_table=11
                     /translation="VRKNRPKYKQIIDAAVVVIAQHGYHQAQVSKIAKQAGVADGTIYL
                     YFKNKEDILISLFEEKMQLFIEKVSEYIAGDLSPSEKLLKMIENHFKVLAADHHLAVVT
                     QLELRQTNLDLRLKINSVLKEYLTLFDQIIREGMEKGEFDSGLDVRLVRQMIFGTVDET
                     VTTWVMNKEKYDLVSLAAPVHQLIINGCGKKTAV"
ORIGIN
        1 ttcggaaagc cgttaaattg cgatgtttgc ggataaatct attaatctct cctgaaaata
       61 tgcgccggct ggctttcatc cttctgctgg tgccgcattc attcggcatg ggcgtctgtt
      121 tgcaaatttg ggtgcagcag cgtttgattt aaagccaaat cgtccaacgt ctttggagaa
      181 aacttcacac tgcctcatga gggctttgga aaaaatttta atgccgtctt ttgagataac
      241 aacgccgttt gttttcgtaa gcctcgtgat tttttatacg gtatccggcg tctggacgcc
      301 ccgcctttta ctaacatgat cgattgtcgg ccggagtttc atttaaaggc accattgaaa
      361 acgattccgt gtcgtgagct tgtggccatt ttactaaaac cgccggcaaa tttccagctt
      421 catctaaaaa tatgaaaaat gtaaaaatcg gagtcaaaaa gagtaaacgc tttatccgca
      481 gatccttccg tttctctccc ccctctttaa accacaaaat cgactgcaac attgcagccg
      541 attttgtttc aaagctttaa ttcccccatg cggagtaatt caacaacagc ttgcgagcgc
      601 cccttgactc ccaatttctg catggcattg gaaatatgat ttcgaactgt tttttcgctg
      661 ataaacaatt cgcttgcgat ttcttttgtt gtcttgtctt gtactaacag ctcgaatact
      721 tctttttctc tttttgtcag cagcggttta tgtgtgaaat cgttgtcctt caactatgat
      781 aaccctcctt gccttcgcca gctctaaacc gcggggatgg gtattttggt tgtcacaata
      841 tcttatgttt tagcgcagcc gggagtgact tggcgaggca aggaacagca caaatcagca
      901 aaaaagggcg gataccggaa atcccttctg tgcaaaagaa gaatgaagca ttatccggca
      961 ttgtaaactg gcagttatgg attctgttta tggcctgtac gaagacggca aagcaggcaa
     1021 gcaattgttg taaaaaatac cacgtattgc cgctcttttc tccgctcgaa ttaatcccca
     1081 acgcacgcac ttaagtttat attatacggc gggatggact ctttcgttca gttgccggat
     1141 gagacataag cttgcgggtc ggcgaatctc gctttttctt ccgccgtcca cggttttcct
     1201 tttccggttg cggccgaaat ttgcaccatt gtcccgcgcc cggtaaaaca gatttcatcc
     1261 gcttcatttt tcgccatata gtgcaagtca acggacgaat tgccgatttt cgagactttt
     1321 acataaatgc ggagcttgtc attgaaaaaa acctgctgca aaaaatcaca ctgcaaatcc
     1381 gccacgaccg ggatggatcc ggtgcctctt tttgcccagt cgcccataaa cccgagctgc
     1441 tggagaaatt caatccgcgc ttgttcaaaa taaataaacg gaacggtatt gttcatatgg
     1501 ccgaacatat cggtttcgga aaaacggacc gtcaccggga gataaaacga aaatccttct
     1561 tcccaggcct cccagtcatc aatataagag atatgttttt tcaatggaat gcctcctttt
     1621 aatgagtgaa cagccattca ttttttgttt gaaaaagagc gccacatcgt actgtttccg
     1681 ctttgatgtg gcactttcgg cattagtcaa ccgtatggtc actgccaaag aattttttaa
     1741 acatataaat ggttgtttca cggtttaacg ctgcgatgga tgttgtcagc gggatacctt
     1801 tcgggcagac ttgcacacag ttttgcgagt tgccacaatt ggcaaggccg ccgtcaacca
     1861 tgatcgcttc aagccgttca tcacggttca tatgaccggt cgggtgcgca ttaaataacc
     1921 gtacttgcga aagcggggcc ggcccgataa agtttgaacg gctgttgaca ttcgggcagg
     1981 cttccaaaca tacgccgcac gtcatgcatt ttgccagttc ataagcccac tgcctttttt
     2041 tctccggcat gcgcggccct tcccctaagt cgtaagtgcc gtcaatcgga atccaggctt
     2101 tcactttttt cagcgagtcg aacatgcggc tgcggtcaat ttgcaaatct cttacaaccg
     2161 ggaaggtccg catcggggca aggcggatcg gctgctccag tttgtccaca agcgctgaac
     2221 aagcctggcg cggcttgccg ttaatcacca tggaacaggc gccgcaaact tcttccaaac
     2281 agttcatttc ccaaacaaca ggtgttgttt tttccccttt ggcattgacc ggattccggc
     2341 ggatttccat cagggccgaa atgacattca tattcggccg gtacggaact tcaaacgttt
     2401 cgtcgtatgg ttctgattcc ggattatcct ggcgttgtat gataaatgta acggtttttt
     2461 gttcacccat ccttattctc ctctttcctt atgaaatcac ccgggcaaaa gccggaaaaa
     2521 gtccgctttc gcccgatccg aatcagtgct tcttcgtgta gtcgcgcacg cgcggcttga
     2581 tcagcgatac atccacatct tcatagctga aaaccggctc attgttcaca gggtcataat
     2641 ttgccatcgt cgttttcagc cattcttcgt cgttgcggtc cggaaaatca ggtttatagt
     2701 gggcgccgcg gctttcatta cggttcaggg cgccgatcgt aatgacgcgc gccagctgca
     2761 gcatgttata cagctgccgt gtaaacgaag ccgcctggtt gctccatttc gatgtatcta
     2821 caacattaat atttttccat ctttccatta attcctgaat cttttcgtcc gttttcttca
     2881 gacggtcatt gtaacggaca accgtcacat tgtctgtcat ccattcgccc agttccttat
     2941 gcaacacata ggcattttcg gttccgtcaa gcgacaatat atcgttccat tttttctcct
     3001 gttcctggac agcacgttca aagacggttg acggcagtgc attcgcgctc ttttcaagcc
     3061 cgtcgatgta gttgacagct tcaggcccgg ctaccatccc gccatagatg gcagaaagca
     3121 gggagtttgc ccctaagcgg ttcgcgccgt gcatcgagta gtcgcattcg cctgctgcga
     3181 acagccccgg aatgctcgta tgctgcttat agtccaccca taatccgccc atggaatagt
     3241 ggacggccgg gaatactttc atcggcactt tatgcgggtc atcgccgaca aatttttcat
     3301 agatttcaat aatcccgccc agtttaacgt ccagttcatg cggatctttg tgcgacaaat
     3361 cgagatagac catgttctcg ccgttaattc cgagtttcaa gtccacgcag acatggaaaa
     3421 tttcacgggt tgcaatatcg cgcggcacga ggttcccgta tgccggatat ttttcttcca
     3481 ggaaatacca cggtttgccg tctttgtacg tccagatgcg cccgccttcc ccgcgtgcgg
     3541 attcactcat cagccgcagt ttgtcatcac ctgggatagc agtcgggtgg atctggataa
     3601 attcgccgtt cgcatacgtt gcgccctgct ggtatacaat agaagccgcc gagccggtat
     3661 tgatcatcga gttggtcgac ttcccgaaaa taatgccaag gccgcctgat gccataatga
     3721 cagcatccgc aggaaaagct ttgatttcca ttgtggtcag gttttgcgaa acaatgccgc
     3781 ggcagatgcc ttcatcgtct ttgataatgc cgagaaattc ccagccttcg tatttcgtga
     3841 caagcccgtc cacttcatgg cgccttacct gttcatccaa tgcgtataaa agctgctggc
     3901 cggttgtcgc gcctgcaaat gctgtgcggt ggtgctgggt gccgccgaaa cgcctgaagt
     3961 ccaaaagccc ttccgacgtg cggttgaaca tgacacccat ccggtcaaac aagtggataa
     4021 tccccggcgc cgcttcgcac atcgctttta ccggcggctg gttggcaagg aagtcgcccc
     4081 cgtataccgt atcgtcaaag tggatccatg gcgaatcccc ttcccctttt gtattgacag
     4141 cgccgttaat gccgccctgt gcgcaaacag agtgcgacct ttttaccggc actaaagaaa
     4201 acagatcaac ctgccggcct gcttctgcaa tttttacagt cgccatcaaa ccggcaagcc
     4261 ctccgccgac aacaatgatt ttgccattag ccaacttgat tcactccctt ttcatacttg
     4321 atgcctctta caaaccagta gactgctatt tttcgagtct tttcattatg caaatgctaa
     4381 taaagccctg acgccgacaa cggaaagcag cacaaagacc acgatcatca catatgtgga
     4441 aatttgctgt gaccggcgtg actgtgtaat gccccagctg accaggaacg accagagacc
     4501 gttggcaaag tggaaaatgg cagccactgt cccaattatg taccaggcga gcatccaacg
     4561 atttgctaaa agatttgcca tcagatcaaa attcaattcc ttgccaagcg ccatttgaat
     4621 gcgtgtttca tagatgtgaa atacgagaaa gatcaggacc agcacaccgc tgattctttg
     4681 caataggtac atccagttcc ggaagtagcc catcgtgccg acattgctcg atgccgtaaa
     4741 cgaaatgtat aagccgtaaa ttgcatggaa cagaagcggc agataaatga atactacttc
     4801 cacaaaaagc aggaacggca ggttttccat aaaaccggct gctttattga aggcagcagc
     4861 accgtttacc gcatagtggt ttacggtcaa gtggatgact aaaaataagc cgatgggtac
     4921 aacacccagc aaagaatgca gtttgcggtt ataaaactct cgatttccag ccacattgta
     4981 tccccctttg tagtgtgaat ttatgcaaag aagacaaatt ttgcatggct tcctcccgca
     5041 taaatatttt ataacaatta tgtgacagtt ttattgtact cccgacaaat gggcacgtca
     5101 aggaaacgca ttcatgaatt tgcgctgaaa atgccgttta tttgtcatat ttgtcagtct
     5161 ttcttccatt tttttaaaat tttttcagta tagctctttt gccatatgct tttgcataaa
     5221 aaaggaattt ttatccaagg cttgtctttt ttcatcggat tttaccgcaa ccggtaccac
     5281 ttccccgtat aacgcggaaa ccggcggaaa aagttccttt tatttttgtg tatacttaaa
     5341 aaatgctttt aagtccggtt ttattttgta tataatatag catatagaaa gaggggaatt
     5401 gcgtgaaatc ttctggcgga aatgaacaaa ccgttgcgga acagctgatg gtacccacat
     5461 tcggatatga gctgttgcgc aatatattaa ttccggatat actcggcaag gaaacgccgg
     5521 atattctgta ctgggcggga aaacatttgg caagaaaatt ccagttgctt acctatgaag
     5581 aaatggtttc ttttttcaaa gaggccggct ggggaacgtt gtcaatcaaa aaagaagaga
     5641 aatatcatat tgaatttgag ttatccgggc cgatgattga acggcagctg gatatgggcg
     5701 caggcgcaga accgacattc aagcttgaag ccgggttttt ggccgagcag taccagatgc
     5761 agaaaaaact gatcacggaa gctgtggaag aagttgcgaa aaaggcaaaa aaaatccgga
     5821 tcaccgtgca gtgggatgcg aaagacccgg ccgaggaata aatatgaaaa agcagggggc
     5881 tcccctgctt tttcatattt tcatatattt tgttccactg catccagttc aaatgcttca
     5941 tgcaggcacc gggcggcccg gaccatttct tttgcatcga caacggtgga tactttgatc
     6001 tcggacgtgc tgatcatttt aatcgcaatg ccgtggtcgg ccagaacctg gaacattttt
     6061 gccgcaacgc ctgggttgga aaccatgccc gagccgatga tggacacttt tgcgaggccg
     6121 gtttccgttt caaaatggtc gatgctgagg gcttctttcc cggcttccaa aagatcggcc
     6181 gtttctttta gatctttatc ttttatcgaa aatgataaat atgttttatg gtccgccgtc
     6241 cggttctgga tgatgatatc gacatcaata tggtgttccg ccagtgtcgt gaatatatcc
     6301 ggcaaattcc ggaagccgtt ttccagcccg aaaatggtta cccttgtaat gccgtcttca
     6361 aatgcaacgc cgcggacaat taaatttttt tccaccgaaa cttcctcctc tattaacgtg
     6421 ccttcctccc tttcaaggct cgaacaaacg atcagcggca cagccgcatt tttggcaaac
     6481 tccaccgccc ttgcatgcag gacgcccgcc ccgaggctcg ccagttcaag catctcatcg
     6541 taggatacag ccttaagctt ccgggcagtc ggaatatagc gcgggtcgga cgtaaacacg
     6601 ccggttacat ccgtgtagat caggcagcgg tcggcatgaa gcgctgctgc aagcgccact
     6661 gccgttgtat ccgagccgcc cctgccgagc gtcgcaattt cgccttccgg ggtaatgccc
     6721 tgaaacccgg cgacaacgac aatttgcccg gctgccagac gggatttgat tttttcagtc
     6781 cggatttccg tgatccgggc gtttccgtgc acgggttccg ttataatgcc ggcctgccaa
     6841 ccggtataag aaacggcatc gtagccgcga tcgatcagcg ccatggcgac aagcgaaatc
     6901 gtcacctgtt cgccggttga aagcagcata tccatttcgc gttttgcagg atacgccgaa
     6961 agttcatttg caagcccgac aagctggtcc gttgttttgc ccatcgcgga gacaacgacg
     7021 acaacatcat ggcctttttc cttttcttca ataatccggt cgaccgtatt ccggatcctt
     7081 tccacatttc caaccgaagt tcccccgaat ttctgaacaa tgattcccaa taactccgcc
     7141 accttctgca gtttataagt aagatgaggc tgtcagattg aaagcaaagc aacttggcgc
     7201 ccatttaaaa aaaagcaatg agaacggata tctcatcgct tttgcatacg cgggtacgca
     7261 gttattcctg tgagatagcg ctccaagaca tttcatcctg acagttccgg acttcttcag
     7321 tacagaacca gcaaaaacgg cattgaggcc atttccactt cggcaaaact tcctttcagg
     7381 aacgatcccg gaagcccaat cttctcccgt tccttactct taagttttgc gcctctatca
     7441 tgtaacggct ttgccggacg ccgggatatc cgctcccgaa agtctgaaac aaagcctgcc
     7501 atatgaaatt atcatgatta taccatatac ggaaaaaccc tgctaggtta ttcttgtaat
     7561 tttttgatta atgtttcgga taccgggcgc gggatgcccg cttccacaaa ttcttccaac
     7621 ttcgcttgct tcattttctt taaggaacca aagtggcgga gcagttgttt tttccgtttc
     7681 ggtccgatgc ccggaatatc gtcaagcgcc gattgaaatg cggattttcc gcgcaattcc
     7741 ctgtggaacg taatcgcaaa ccggtgcact tcatcctgga tgcgctggag caggtaaaat
     7801 tcctggctgt tccgcccgag cggcacgact tccagcgggt tgccgaacaa aagctgcgat
     7861 gtattgtgct tctcatcctt tgccaggccg ccgagcggaa tctcaagccc gagctcattt
     7921 tcgagcacat cccttgccgc gtcaatttgc ccttttccac cgtcaatgat gatgaggtcc
     7981 ggaagcggca agttttccct cagggcacgg atgtaacggc ggcggatcac ttcgcgcatc
     8041 gattcataat catccggccc ttccaccgtt ttgattttat atttgcggta ttcttttttt
     8101 gccggcttgc cgtccacaaa cacgaccatc gccgaaaccg ggtttgtccc ctggatattc
     8161 gaattatcga acgcttcaat ccggtgcggc gtatagatgc cgagcttttc gcctagattt
     8221 tcaacggctt tgatcgtccg ttcctcgtcc cgttcaatca acgcaaattt ttctttcaaa
     8281 gcaatctttg cgtttttctc ggccattaac acaagttccc gtttctggcc tttttttggc
     8341 tggagcactt tgatttccag cagttgttct gccagttccc ggtctgcttt ttccgtaatc
     8401 agcacttctt tcggcttaat atgctccggt ttggcgtaaa actgccccaa atagctcaaa
     8461 aattcctctt ccggctcatc gtaagacgga aaaagcgaga catcccgttc aatcagcttt
     8521 ccttggcgca tgaaaaacac ctggacacac atccagcctt tatccactgc gtagccgaaa
     8581 atgtcgcggt ccgtaaaatc cgtcatggta attttctgtt tttccatcgt catttcaata
     8641 ttggcgatct ggtcgcggta ttcttttgcc cgctcaaatt caagtttttc agcagcctca
     8701 tgcatttttt cttccagttc ttttttgatt tccgtgtagc ccccgttcaa aaagcgggta
     8761 atttggtcgg tgatctcttt gtatgtttct tctttcacct cattgacaca cggcgcaagg
     8821 cactggccca aatggtaata aaggcagacg cggtccggca tattggtgca tttccgcaaa
     8881 ggatacaacc ggtccagcag cttttttgtt tcattggccg cctgcacgtt cggatacggg
     8941 ccaaaatatt ttcccttatc tttcttcact ttccgggtgg tgatcagacg cgggtggcgt
     9001 tcatgggtca gcttaatata cgggtatgtt ttatcatctt ttagcatgat gttgtatttc
     9061 gggtcatgct ttttgattaa gttgatttca agaataaggg cttcaatatt ggaagaagtg
     9121 acaatatact caaagtcttc gatctcgctg acaagccgct gcgtttttgc gtcatgcgaa
     9181 ccggaaaagt aagagcggac acggtttttt aaaattttgg ccttcccgac ataaatgatg
     9241 gtcccctgtc tgtctttcat taagtagcag ccgggctggg cgggcaggag ggcaagttta
     9301 ttgcggatcg tttcgttcaa tttttcttca cctcaaaatc ctgcgttctg taaaaaaccc
     9361 ggaccacagc cggtccggat tttaaatgca tttgctcacg gcttgaagcc gcgcgtttat
     9421 tgtattataa atgtttgttc actaattctt gcaaagcttc tttcggctgg taaccgatca
     9481 ctttgtcgac cggtttgccg tctttcatga gaacaagggt cggaatgctc atgatgccga
     9541 atttgctggc tgtttcctgg ttctcgtcaa cgtccacttt gacaattttc accttgtcgc
     9601 ccatttcagc atcgatttct tcaagtaccg gtgcaatcat tttgcacggg ccgcaccatg
     9661 ttgcccaaaa atccgttaat accaaacctt ggctgacttc ctgatcgaaa gtcgcgtcgg
     9721 tagcatgtgt aattgccata ttgaaagaac cctcctaaat caaactatta ctgcttggga
     9781 ttagtatatc atcctttatc atatgttgcg aacaatttgt ccggtccagg taagcagtaa
     9841 tgattttatt attttatacc ctttttccgc gaatatccaa cagaaaacag gcccggaacg
     9901 atttttttcg tccgggcccg ggatttacgc cgatgtgact ttcagttttt tgatttcttc
     9961 cgtgagaagc gggaccactt caaacaggtc gccgacgatg ccgtagtccg ctacgttgaa
    10021 gatgtttgct tccggatctt tgttaatggc cacaatgact tttgagttgg acatgccggc
    10081 caaatgctgg atggcgccgg aaatgccgca tgcgatatac aaatccggtg tcaccacttt
    10141 gcccgtctgc ccgatttgca gggaataatc gcagtatccg gcgtcacatg cgccgcgcga
    10201 agccccaacc gcgccgccga gcacatcggc aagctctttc agcggtttga agccgtccgc
    10261 gcttttcacg ccgcggccgc ctgaaacgat gactttcgct tccgaaaggt caaccccttc
    10321 acttactttc cggactactt ctttgatgac cgtgcgcaaa tctttaattt ccgcctggac
    10381 ggtttcgata tcccctgtcc gcgattcatc tttttcaagc gggctgatgt tgttcggccg
    10441 gatggtcgca aagatgatcc cgtctgttac gatctttttc tcaaacgctt tgccggagta
    10501 aatcgggcgg gtaaagacga catgttctcc ggctgattcc actgcggtcg catccgaaat
    10561 caggccggca tccaatttag ccgctacttt tggggccagg tctttgccaa gcgccgtatg
    10621 gccgattaag atgccgtccg gcttttcaga ttcgacaacc gcaagcaatg cttgggaaaa
    10681 accgtctgaa gaatagcttt tcagcttctc gtcttccacc acggcaacac ggtcagcacc
    10741 gtattgaatc atgtctttcc ccaaatcttt cacagcgtcc ccgatcaaaa cgccgactac
    10801 ttccccgcct tccgctaccg tttttccggc ggcaatggtt tcatatgata cattgcggag
    10861 cgacccgtca cggacttcgc ccactactaa tacttttcga ctcatgctga tcccctccat
    10921 ttccggtttc ttcgcttaaa tcacttttgc ttcggcatgc aataattgga caagttcttt
    10981 tacctggtcg gcgatttcgc cttcaagcac ttttcctgct tcttttttcg gcggcaggta
    11041 aacctcgata gttttggttt tcggctccac gtcttcttct tcaaggtcaa gatcatccag
    11101 ttccagttct tcaagcggtt ttttcttcgc tttcatgatc cccggtagcg aaggataacg
    11161 cggctcattt aagccctgct gcgctgtgac gagaagcgga aggtccgttt caatgatttc
    11221 ggaatcccct tcgacatctc ttgtgaccgt cgctttgccg ccgtcaattt ccagattggt
    11281 aattgtcgtt acatacggga tgccgagcaa ctccgccacc cgcggtccga cctgtccgga
    11341 agcgttgtca atggcgacat tcccgccgat aatgaggtct ggttcctgct ctttcaaata
    11401 agcggcaagc acttttgacg ttgtgacctg gtcgcttgct tccacatcgt cttcaatatt
    11461 aatgaggact gctttatcca cacccatcgc aagcgccgtc cgcaattgct tttcggcatc
    11521 ttcattgccg actgtgacca ctgtgacttc gccgccctgg gcatcccgca cctggatggc
    11581 ctcttcaacg gcgtattcat cgtacgggtt gatgatatat tccgccccgt catcctggat
    11641 gcggccgttt gcaattgcaa tcttttcttc tgtgtcaaag gtccgtttta ataatacgaa
    11701 gatattcatg ccgttccctc cctgaatcgt taaaaaataa aatcatttaa gcgcatacaa
    11761 aataaaaatg ttatgcccct gtaaaacgcg gttccctttt ttcaataaaa gctttgatac
    11821 cttcctctgc atcttttgag ccgaacagct caagaaaacg tgcggattcc tgctccaagc
    11881 ctttttcgta atcatttgtt tttgcataat tgacgagttc aatagaggct ttcagggcca
    11941 gcgggctttt ctttgcaatt ttttcagcca gcgcctttgc tttcgggagc agttcctctt
    12001 ccttataagc atggtttgca agcccctgct gcacggcctc cgttccggtc agcggttcgc
    12061 ttgtccacag catttcaaac gctttgccgc gcccgatata ctttggcagc cgctgcgttc
    12121 cggcaaaacc cggcacaagc ccgaggctca gttccggaag gccgagcttc gcattttctg
    12181 tgacaagccg gatatggcat gccatcgcaa gttcgagccc gccgccaagt gccgcgccgt
    12241 ggattgcggc gatgaccggt ttcgggaacg cttccacttt ttcgaacaat tcctggccgg
    12301 aaaccgctat cgcatcggag ccgccggatt cccttaattg gacaaattct ttaatatccg
    12361 ctcccgccga gaaaaatctt cctttcccgt aaaggagcac gacccgggtt tcaggatcgt
    12421 tttcaagctg gccaaacgct tgcgcaagtt cttttaaaag ggcctgcgca agcgcgttgg
    12481 cgggcggcct gttcatttca atgcaggcaa ccgcattttc ccgtttgatc gtaataaatt
    12541 ccatcccgtc tccaaccccc ttgtgaaagc tgcggcaatt aaaccgccgt ttttttgccg
    12601 cagccgttaa tgatcaattg atggacggga gcagccagtg aaacgaggtc gtatttttct
    12661 ttattcatca cccatgtcgt caccgtttca tcgactgtcc cgaaaatcat ctgtcggacg
    12721 agccggacgt caagcccgga atcgaattcg cctttttcca tgccttcgcg gataatttgg
    12781 tcaaagagcg tcaaatattc tttcagcacg ctgttgattt taagccgcag gtctaaattt
    12841 gtctgccgca gttccagctg ggtcacgacc gccaaatggt ggtcggcggc aaggactttg
    12901 aagtggtttt cgatcatctt gagcaacttt tcggaagggg aaaggtcccc tgcaatatat
    12961 tcggaaacct tttcgataaa cagctgcatt ttttcttcaa acaaagaaat caggatatct
    13021 tctttgtttt taaaatacaa ataaattgtg ccgtccgcta cgcccgcctg ttttgcaatt
    13081 tttgaaacct gtgcctgatg atagccgtgt tgtgcgataa ccaccactgc tgcatcaata
    13141 atttgtttgt actttggcct gtttttcctc acgggctatc acctttcaat ctcatgatct
    13201 gtcaatttgg ccggccggtt tgatggcggc cggaaaatga atgaccattc attcatattt
    13261 tcatattata caggaatgca gcatttgtca agtcctgttt ataaaaaatt ttccttaacc
    13321 gatcttctct ccttcatttt ccatcttttc tttttcttct gcaaccaatg agcgccgcaa
    13381 aattttcccg acggccgttt tcggcagttc atcccggaat tcgtaaatgc gcgggacttt
    13441 ataggccgcc agatattggc gcgcaaaccg gtccagttct tcttccgtta ctgccatatt
    13501 ctctttcagc acaatatagg ctttgacggt ttccccgcgg tacgggtgcg gcacgccggc
    13561 caccacggct tcctggacgg cagggtgctc atacagcact tcttctactt cgcgcggata
    13621 aatattatag ccgcctgcaa tgatgatgtc ttttttccgg tcgacaatat aaaaataacc
    13681 ttcttcgtcc atataagcca ggtcccccgt aaacagccac ccgtctttca gcacttcctg
    13741 cgtttcttcc gggcggttcc agtagccttt catcacttgc ggccctttta ccgccagctc
    13801 gccgacttca ccgggcggca acggcctgcc gtcttcgagc gaccggattt cgcagtccgt
    13861 atccggccat ggcacgccga tgctaccttt gacgcgtttt ccccatacaa aattggcatg
    13921 ggtgacggga gacgattcac tgaggccata cccttccaca agcttgccgc cggttacctc
    13981 ttcaaatttc tgctggactt ctaccggcag cggggcagaa ccgctgatgc atgcttcaat
    14041 cgatgacaaa tcatattcct tgattttcgg gtggtttaaa agcccgatat aaatggttgg
    14101 cgcacccgga aacagggtcg gccgctgttt ttcgatcgtc ttcagcagcg actccgcatc
    14161 aaaacgcgga attaaaatca ttttaaagcc ctgcatgaca gaaagaatca gcacggtcgt
    14221 catgccatac acgtggaaaa acggaagcat gccgagcacc acttcttctc cttttttggt
    14281 cctgtacatc cagg
//
