LOCUS       c00026_gnlPro..        14294 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|INOCIFIG_28.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 21:30:56
            Original ID  :: gnl|Prokka|INOCIFIG_28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 65406
            Orig. end    :: 79700
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14294
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[75406:77998]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12592
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14294
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14294
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1123..1716
                     /locus_tag="ctg26_64"
                     /transl_table=11
                     /translation="VRKNRPKYKQIIDAAVVVIAQHGYHQAQVSKIAKQAGVADGTIYL
                     YFKNKEDILISLFEEKMQLFIEKVSEYIAGDLSPSEKLLKMIENHFKVLAADHHLAVVT
                     QLELRQTNLDLRLKINSVLKEYLTLFDQIIREGMEKGEFDSGLDVRLVRQMIFGTVDET
                     VTTWVMNKEKYDLVSLAAPVHQLIINGCGKKTAV"
     CDS             1751..2524
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_65"
                     /sec_met_domain="ECH_1 (E-value: 5.8e-68, bitscore: 221.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFITIKRENAVACIEMNRPPANALAQALLKELAQAFGQLENDPE
                     TRVVLLYGKGRFFSAGADIKEFVQLRESGGSDAIAVSGQELFEKVEAFPKPVIAAIHGA
                     ALGGGLELAMACHIRLVTENAKLGLPELSLGLVPGFAGTQRLPKYIGRGKAFEMLWTSE
                     PLTGTEAVQQGLANHAYKEEELLPKAKALAEKIAKKSPLALKASIELVNYAKTNDYEKG
                     LEQESARFLELFGSKDAEEGIKAFIEKREPRFTGA"
     CDS             2586..3359
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 170.7;
                     E-value: 9.7e-53)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg26_66"
                     /sec_met_domain="ETF (E-value: 1.2e-52, bitscore: 170.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIFVLLKRTFDTEEKIAIANGRIQDDGAEYIINPYDEYAVEEAI
                     QVRDAQGGEVTVVTVGNEDAEKQLRTALAMGVDKAVLINIEDDVEASDQVTTSKVLAAY
                     LKEQEPDLIIGGNVAIDNASGQVGPRVAELLGIPYVTTITNLEIDGGKATVTRDVEGDS
                     EIIETDLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLEEEDVEPKTKTIE
                     VYLPPKKEAGKVLEGEIADQVKELVQLLHAEAKVI"
     CDS             3390..4370
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 147.9;
                     E-value: 9.8e-46)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg26_67"
                     /sec_met_domain="ETF (E-value: 1.2e-45, bitscore: 147.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 2.5e-38, bitscore:
                     122.4, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKVLVVGEVRDGSLRNVSYETIAAGKTVAEGGEVVGVLIGDAV
                     KDLGKDMIQYGADRVAVVEDEKLKSYSSDGFSQALLAVVESEKPDGILIGHTALGKDLA
                     PKVAAKLDAGLISDATAVESAGEHVVFTRPIYSGKAFEKKIVTDGIIFATIRPNNISPL
                     EKDESRTGDIETVQAEIKDLRTVIKEVVRKVSEGVDLSEAKVIVSGGRGVKSADGFKPL
                     KELADVLGGAVGASRGACDAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEANIFNVADYGIVGDLFEVVPLLTEEIKKLKVTSA"
     CDS             4655..4870
                     /locus_tag="ctg26_68"
                     /transl_table=11
                     /translation="MIAPVLEEIDAEMGDKVKIVKVDVDENQETASKFGIMSIPTLVLM
                     KDGKPVDKVIGYQPKEALQELVNKHL"
     CDS             4975..6747
                     /locus_tag="ctg26_69"
                     /transl_table=11
                     /translation="LNETIRNKLALLPAQPGCYLMKDRQGTIIYVGKAKILKNRVRSYF
                     SGSHDAKTQRLVSEIEDFEYIVTSSNIEALILEINLIKKHDPKYNIMLKDDKTYPYIKL
                     THERHPRLITTRKVKKDKGKYFGPYPNVQAANETKKLLDRLYPLRKCTNMPDRVCLYYH
                     LGQCLAPCVNEVKEETYKEITDQITRFLNGGYTEIKKELEEKMHEAAEKLEFERAKEYR
                     DQIANIEMTMEKQKITMTDFTDRDIFGYAVDKGWMCVQVFFMRQGKLIERDVSLFPSYD
                     EPEEEFLSYLGQFYAKPEHIKPKEVLITEKADRELAEQLLEIKVLQPKKGQKRELVLMA
                     EKNAKIALKEKFALIERDEERTIKAVENLGEKLGIYTPHRIEAFDNSNIQGTNPVSAMV
                     VFVDGKPAKKEYRKYKIKTVEGPDDYESMREVIRRRYIRALRENLPLPDLIIIDGGKGQ
                     IDAARDVLENELGLEIPLGGLAKDEKHNTSQLLFGNPLEVVPLGRNSQEFYLLQRIQDE
                     VHRFAITFHRELRGKSAFQSALDDIPGIGPKRKKQLLRHFGSLKKMKQAKLEEFVEAGI
                     PRPVSETLIKKLQE"
     CDS             7165..8394
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_70"
                     /sec_met_domain="AA_kinase (E-value: 7.9e-58, bitscore:
                     188.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGIIVQKFGGTSVGNVERIRNTVDRIIEEKEKGHDVVVVVSAMGK
                     TTDQLVGLANELSAYPAKREMDMLLSTGEQVTISLVAMALIDRGYDAVSYTGWQAGIIT
                     EPVHGNARITEIRTEKIKSRLAAGQIVVVAGFQGITPEGEIATLGRGGSDTTAVALAAA
                     LHADRCLIYTDVTGVFTSDPRYIPTARKLKAVSYDEMLELASLGAGVLHARAVEFAKNA
                     AVPLIVCSSLEREEGTLIEEEVSVEKNLIVRGVAFEDGITRVTIFGLENGFRNLPDIFT
                     TLAEHHIDVDIIIQNRTADHKTYLSFSIKDKDLKETADLLEAGKEALSIDHFETETGLA
                     KVSIIGSGMVSNPGVAAKMFQVLADHGIAIKMISTSEIKVSTVVDAKEMVRAARCLHEA
                     FELDAVEQNI"
     CDS             complement(8434..8892)
                     /locus_tag="ctg26_71"
                     /transl_table=11
                     /translation="VKSSGGNEQTVAEQLMVPTFGYELLRNILIPDILGKETPDILYWA
                     GKHLARKFQLLTYEEMVSFFKEAGWGTLSIKKEEKYHIEFELSGPMIERQLDMGAGAEP
                     TFKLEAGFLAEQYQMQKKLITEAVEEVAKKAKKIRITVQWDAKDPAEE"
     CDS             9321..9929
                     /locus_tag="ctg26_72"
                     /transl_table=11
                     /translation="VAGNREFYNRKLHSLLGVVPIGLFLVIHLTVNHYAVNGAAAFNKA
                     AGFMENLPFLLFVEVVFIYLPLLFHAIYGLYISFTASSNVGTMGYFRNWMYLLQRISGV
                     LVLIFLVFHIYETRIQMALGKELNFDLMANLLANRWMLAWYIIGTVAAIFHFANGLWSF
                     LVSWGITQSRRSQQISTYVMIVVFVLLSVVGVRALLAFA"
     CDS             10001..11752
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 300.3; E-value:
                     8.6e-92)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_73"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.1e-91, bitscore:
                     300.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-47,
                     bitscore: 153.6, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LANGKIIVVGGGLAGLMATVKIAEAGRQVDLFSLVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMCEAAPGIIHLFDRMGVMFN
                     RTSEGLLDFRRFGGTQHHRTAFAGATTGQQLLYALDEQVRRHEVDGLVTKYEGWEFLGI
                     IKDDEGICRGIVSQNLTTMEIKAFPADAVIMASGGLGIIFGKSTNSMINTGSAASIVYQ
                     QGATYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFHVCVDLKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFVGDDP
                     HKVPMKVFPAVHYSMGGLWVDYKQHTSIPGLFAAGECDYSMHGANRLGANSLLSAIYGG
                     MVAGPEAVNYIDGLEKSANALPSTVFERAVQEQEKKWNDILSLDGTENAYVLHKELGEW
                     MTDNVTVVRYNDRLKKTDEKIQELMERWKNINVVDTSKWSNQAASFTRQLYNMLQLARV
                     ITIGALNRNESRGAHYKPDFPDRNDEEWLKTTMANYDPVNNEPVFSYEDVDVSLIKPRV
                     RDYTKKH"
     CDS             11825..12592
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 100.1; E-value: 2.2e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_74"
                     /sec_met_domain="Fer4_10 (E-value: 2.1e-11, bitscore: 36.2,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.8e-31, bitscore: 100.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00038, bitscore: 13.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEQKTVTFIIQRQDNPESEPYDETFEVPYRPNMNVISALMEIRR
                     NPVNAKGEKTTPVVWEMNCLEEVCGACSMVINGKPRQACSALVDKLEQPIRLAPMRTFP
                     VVRDLQIDRSRMFDSLKKVKAWIPIDGTYDLGEGPRMPEKKRQWAYELAKCMTCGVCLE
                     ACPNVNSRSNFIGPAPLSQVRLFNAHPTGHMNRDERLEAIMVDGGLANCGNSQNCVQVC
                     PKGIPLTTSIAALNRETTIYMFKKFFGSDHTVD"
     CDS             12691..13167
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_75"
                     /sec_met_domain="HBT (E-value: 2.4e-17, bitscore: 55.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 7.5e-17, bitscore: 54.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKKHISYIDDWEAWEEGFSFYLPVTVRFSETDMFGHMNNTVPFIY
                     FEQARIEFLQQLGFMGDWAKRGTGSIPVVADLQCDFLQQVFFNDKLRIYVKVSKIGNSS
                     VDLHYMAKNEADEICFTGRGTMVQISAATGKGKPWTAEEKARFADPQAYVSSGN"
     CDS             13522..13746
                     /locus_tag="ctg26_76"
                     /transl_table=11
                     /translation="LKDNDFTHKPLLTKREKEVFELLVQDKTTKEIASELFISEKTVRN
                     HISNAMQKLGVKGRSQAVVELLRMGELKL"
     CDS             complement(14143..14292)
                     /locus_tag="ctg26_77"
                     /transl_table=11
                     /translation="RKAVKLRCLRINLLISPENMRRLAFILLLVPHSFGMGVCLQIWVQ
                     QRLI"
ORIGIN
        1 cctggatgta caggaccaaa aaaggagaag aagtggtgct cggcatgctt ccgtttttcc
       61 acgtgtatgg catgacgacc gtgctgattc tttctgtcat gcagggcttt aaaatgattt
      121 taattccgcg ttttgatgcg gagtcgctgc tgaagacgat cgaaaaacag cggccgaccc
      181 tgtttccggg tgcgccaacc atttatatcg ggcttttaaa ccacccgaaa atcaaggaat
      241 atgatttgtc atcgattgaa gcatgcatca gcggttctgc cccgctgccg gtagaagtcc
      301 agcagaaatt tgaagaggta accggcggca agcttgtgga agggtatggc ctcagtgaat
      361 cgtctcccgt cacccatgcc aattttgtat ggggaaaacg cgtcaaaggt agcatcggcg
      421 tgccatggcc ggatacggac tgcgaaatcc ggtcgctcga agacggcagg ccgttgccgc
      481 ccggtgaagt cggcgagctg gcggtaaaag ggccgcaagt gatgaaaggc tactggaacc
      541 gcccggaaga aacgcaggaa gtgctgaaag acgggtggct gtttacgggg gacctggctt
      601 atatggacga agaaggttat ttttatattg tcgaccggaa aaaagacatc atcattgcag
      661 gcggctataa tatttatccg cgcgaagtag aagaagtgct gtatgagcac cctgccgtcc
      721 aggaagccgt ggtggccggc gtgccgcacc cgtaccgcgg ggaaaccgtc aaagcctata
      781 ttgtgctgaa agagaatatg gcagtaacgg aagaagaact ggaccggttt gcgcgccaat
      841 atctggcggc ctataaagtc ccgcgcattt acgaattccg ggatgaactg ccgaaaacgg
      901 ccgtcgggaa aattttgcgg cgctcattgg ttgcagaaga aaaagaaaag atggaaaatg
      961 aaggagagaa gatcggttaa ggaaaatttt ttataaacag gacttgacaa atgctgcatt
     1021 cctgtataat atgaaaatat gaatgaatgg tcattcattt tccggccgcc atcaaaccgg
     1081 ccggccaaat tgacagatca tgagattgaa aggtgatagc ccgtgaggaa aaacaggcca
     1141 aagtacaaac aaattattga tgcagcagtg gtggttatcg cacaacacgg ctatcatcag
     1201 gcacaggttt caaaaattgc aaaacaggcg ggcgtagcgg acggcacaat ttatttgtat
     1261 tttaaaaaca aagaagatat cctgatttct ttgtttgaag aaaaaatgca gctgtttatc
     1321 gaaaaggttt ccgaatatat tgcaggggac ctttcccctt ccgaaaagtt gctcaagatg
     1381 atcgaaaacc acttcaaagt ccttgccgcc gaccaccatt tggcggtcgt gacccagctg
     1441 gaactgcggc agacaaattt agacctgcgg cttaaaatca acagcgtgct gaaagaatat
     1501 ttgacgctct ttgaccaaat tatccgcgaa ggcatggaaa aaggcgaatt cgattccggg
     1561 cttgacgtcc ggctcgtccg acagatgatt ttcgggacag tcgatgaaac ggtgacgaca
     1621 tgggtgatga ataaagaaaa atacgacctc gtttcactgg ctgctcccgt ccatcaattg
     1681 atcattaacg gctgcggcaa aaaaacggcg gtttaattgc cgcagctttc acaagggggt
     1741 tggagacggg atggaattta ttacgatcaa acgggaaaat gcggttgcct gcattgaaat
     1801 gaacaggccg cccgccaacg cgcttgcgca ggccctttta aaagaacttg cgcaagcgtt
     1861 tggccagctt gaaaacgatc ctgaaacccg ggtcgtgctc ctttacggga aaggaagatt
     1921 tttctcggcg ggagcggata ttaaagaatt tgtccaatta agggaatccg gcggctccga
     1981 tgcgatagcg gtttccggcc aggaattgtt cgaaaaagtg gaagcgttcc cgaaaccggt
     2041 catcgccgca atccacggcg cggcacttgg cggcgggctc gaacttgcga tggcatgcca
     2101 tatccggctt gtcacagaaa atgcgaagct cggccttccg gaactgagcc tcgggcttgt
     2161 gccgggtttt gccggaacgc agcggctgcc aaagtatatc gggcgcggca aagcgtttga
     2221 aatgctgtgg acaagcgaac cgctgaccgg aacggaggcc gtgcagcagg ggcttgcaaa
     2281 ccatgcttat aaggaagagg aactgctccc gaaagcaaag gcgctggctg aaaaaattgc
     2341 aaagaaaagc ccgctggccc tgaaagcctc tattgaactc gtcaattatg caaaaacaaa
     2401 tgattacgaa aaaggcttgg agcaggaatc cgcacgtttt cttgagctgt tcggctcaaa
     2461 agatgcagag gaaggtatca aagcttttat tgaaaaaagg gaaccgcgtt ttacaggggc
     2521 ataacatttt tattttgtat gcgcttaaat gattttattt tttaacgatt cagggaggga
     2581 acggcatgaa tatcttcgta ttattaaaac ggacctttga cacagaagaa aagattgcaa
     2641 ttgcaaacgg ccgcatccag gatgacgggg cggaatatat catcaacccg tacgatgaat
     2701 acgccgttga agaggccatc caggtgcggg atgcccaggg cggcgaagtc acagtggtca
     2761 cagtcggcaa tgaagatgcc gaaaagcaat tgcggacggc gcttgcgatg ggtgtggata
     2821 aagcagtcct cattaatatt gaagacgatg tggaagcaag cgaccaggtc acaacgtcaa
     2881 aagtgcttgc cgcttatttg aaagagcagg aaccagacct cattatcggc gggaatgtcg
     2941 ccattgacaa cgcttccgga caggtcggac cgcgggtggc ggagttgctc ggcatcccgt
     3001 atgtaacgac aattaccaat ctggaaattg acggcggcaa agcgacggtc acaagagatg
     3061 tcgaagggga ttccgaaatc attgaaacgg accttccgct tctcgtcaca gcgcagcagg
     3121 gcttaaatga gccgcgttat ccttcgctac cggggatcat gaaagcgaag aaaaaaccgc
     3181 ttgaagaact ggaactggat gatcttgacc ttgaagaaga agacgtggag ccgaaaacca
     3241 aaactatcga ggtttacctg ccgccgaaaa aagaagcagg aaaagtgctt gaaggcgaaa
     3301 tcgccgacca ggtaaaagaa cttgtccaat tattgcatgc cgaagcaaaa gtgatttaag
     3361 cgaagaaacc ggaaatggag gggatcagca tgagtcgaaa agtattagta gtgggcgaag
     3421 tccgtgacgg gtcgctccgc aatgtatcat atgaaaccat tgccgccgga aaaacggtag
     3481 cggaaggcgg ggaagtagtc ggcgttttga tcggggacgc tgtgaaagat ttggggaaag
     3541 acatgattca atacggtgct gaccgtgttg ccgtggtgga agacgagaag ctgaaaagct
     3601 attcttcaga cggtttttcc caagcattgc ttgcggttgt cgaatctgaa aagccggacg
     3661 gcatcttaat cggccatacg gcgcttggca aagacctggc cccaaaagta gcggctaaat
     3721 tggatgccgg cctgatttcg gatgcgaccg cagtggaatc agccggagaa catgtcgtct
     3781 ttacccgccc gatttactcc ggcaaagcgt ttgagaaaaa gatcgtaaca gacgggatca
     3841 tctttgcgac catccggccg aacaacatca gcccgcttga aaaagatgaa tcgcggacag
     3901 gggatatcga aaccgtccag gcggaaatta aagatttgcg cacggtcatc aaagaagtag
     3961 tccggaaagt aagtgaaggg gttgaccttt cggaagcgaa agtcatcgtt tcaggcggcc
     4021 gcggcgtgaa aagcgcggac ggcttcaaac cgctgaaaga gcttgccgat gtgctcggcg
     4081 gcgcggttgg ggcttcgcgc ggcgcatgtg acgccggata ctgcgattat tccctgcaaa
     4141 tcgggcagac gggcaaagtg gtgacaccgg atttgtatat cgcatgcggc atttccggcg
     4201 ccatccagca tttggccggc atgtccaact caaaagtcat tgtggccatt aacaaagatc
     4261 cggaagcaaa catcttcaac gtagcggact acggcatcgt cggcgacctg tttgaagtgg
     4321 tcccgcttct cacggaagaa atcaaaaaac tgaaagtcac atcggcgtaa atcccgggcc
     4381 cggacgaaaa aaatcgttcc gggcctgttt tctgttggat attcgcggaa aaagggtata
     4441 aaataataaa atcattactg cttacctgga ccggacaaat tgttcgcaac atatgataaa
     4501 ggatgatata ctaatcccaa gcagtaatag tttgatttag gagggttctt tcaatatggc
     4561 aattacacat gctaccgacg cgactttcga tcaggaagtc agccaaggtt tggtattaac
     4621 ggatttttgg gcaacatggt gcggcccgtg caaaatgatt gcaccggtac ttgaagaaat
     4681 cgatgctgaa atgggcgaca aggtgaaaat tgtcaaagtg gacgttgacg agaaccagga
     4741 aacagccagc aaattcggca tcatgagcat tccgaccctt gttctcatga aagacggcaa
     4801 accggtcgac aaagtgatcg gttaccagcc gaaagaagct ttgcaagaat tagtgaacaa
     4861 acatttataa tacaataaac gcgcggcttc aagccgtgag caaatgcatt taaaatccgg
     4921 accggctgtg gtccgggttt tttacagaac gcaggatttt gaggtgaaga aaaattgaac
     4981 gaaacgatcc gcaataaact tgccctcctg cccgcccagc ccggctgcta cttaatgaaa
     5041 gacagacagg ggaccatcat ttatgtcggg aaggccaaaa ttttaaaaaa ccgtgtccgc
     5101 tcttactttt ccggttcgca tgacgcaaaa acgcagcggc ttgtcagcga gatcgaagac
     5161 tttgagtata ttgtcacttc ttccaatatt gaagccctta ttcttgaaat caacttaatc
     5221 aaaaagcatg acccgaaata caacatcatg ctaaaagatg ataaaacata cccgtatatt
     5281 aagctgaccc atgaacgcca cccgcgtctg atcaccaccc ggaaagtgaa gaaagataag
     5341 ggaaaatatt ttggcccgta tccgaacgtg caggcggcca atgaaacaaa aaagctgctg
     5401 gaccggttgt atcctttgcg gaaatgcacc aatatgccgg accgcgtctg cctttattac
     5461 catttgggcc agtgccttgc gccgtgtgtc aatgaggtga aagaagaaac atacaaagag
     5521 atcaccgacc aaattacccg ctttttgaac gggggctaca cggaaatcaa aaaagaactg
     5581 gaagaaaaaa tgcatgaggc tgctgaaaaa cttgaatttg agcgggcaaa agaataccgc
     5641 gaccagatcg ccaatattga aatgacgatg gaaaaacaga aaattaccat gacggatttt
     5701 acggaccgcg acattttcgg ctacgcagtg gataaaggct ggatgtgtgt ccaggtgttt
     5761 ttcatgcgcc aaggaaagct gattgaacgg gatgtctcgc tttttccgtc ttacgatgag
     5821 ccggaagagg aatttttgag ctatttgggg cagttttacg ccaaaccgga gcatattaag
     5881 ccgaaagaag tgctgattac ggaaaaagca gaccgggaac tggcagaaca actgctggaa
     5941 atcaaagtgc tccagccaaa aaaaggccag aaacgggaac ttgtgttaat ggccgagaaa
     6001 aacgcaaaga ttgctttgaa agaaaaattt gcgttgattg aacgggacga ggaacggacg
     6061 atcaaagccg ttgaaaatct aggcgaaaag ctcggcatct atacgccgca ccggattgaa
     6121 gcgttcgata attcgaatat ccaggggaca aacccggttt cggcgatggt cgtgtttgtg
     6181 gacggcaagc cggcaaaaaa agaataccgc aaatataaaa tcaaaacggt ggaagggccg
     6241 gatgattatg aatcgatgcg cgaagtgatc cgccgccgtt acatccgtgc cctgagggaa
     6301 aacttgccgc ttccggacct catcatcatt gacggtggaa aagggcaaat tgacgcggca
     6361 agggatgtgc tcgaaaatga gctcgggctt gagattccgc tcggcggcct ggcaaaggat
     6421 gagaagcaca atacatcgca gcttttgttc ggcaacccgc tggaagtcgt gccgctcggg
     6481 cggaacagcc aggaatttta cctgctccag cgcatccagg atgaagtgca ccggtttgcg
     6541 attacgttcc acagggaatt gcgcggaaaa tccgcatttc aatcggcgct tgacgatatt
     6601 ccgggcatcg gaccgaaacg gaaaaaacaa ctgctccgcc actttggttc cttaaagaaa
     6661 atgaagcaag cgaagttgga agaatttgtg gaagcgggca tcccgcgccc ggtatccgaa
     6721 acattaatca aaaaattaca agaataacct agcagggttt ttccgtatat ggtataatca
     6781 tgataatttc atatggcagg ctttgtttca gactttcggg agcggatatc ccggcgtccg
     6841 gcaaagccgt tacatgatag aggcgcaaaa cttaagagta aggaacggga gaagattggg
     6901 cttccgggat cgttcctgaa aggaagtttt gccgaagtgg aaatggcctc aatgccgttt
     6961 ttgctggttc tgtactgaag aagtccggaa ctgtcaggat gaaatgtctt ggagcgctat
     7021 ctcacaggaa taactgcgta cccgcgtatg caaaagcgat gagatatccg ttctcattgc
     7081 ttttttttaa atgggcgcca agttgctttg ctttcaatct gacagcctca tcttacttat
     7141 aaactgcaga aggtggcgga gttattggga atcattgttc agaaattcgg gggaacttcg
     7201 gttggaaatg tggaaaggat ccggaatacg gtcgaccgga ttattgaaga aaaggaaaaa
     7261 ggccatgatg ttgtcgtcgt tgtctccgcg atgggcaaaa caacggacca gcttgtcggg
     7321 cttgcaaatg aactttcggc gtatcctgca aaacgcgaaa tggatatgct gctttcaacc
     7381 ggcgaacagg tgacgatttc gcttgtcgcc atggcgctga tcgatcgcgg ctacgatgcc
     7441 gtttcttata ccggttggca ggccggcatt ataacggaac ccgtgcacgg aaacgcccgg
     7501 atcacggaaa tccggactga aaaaatcaaa tcccgtctgg cagccgggca aattgtcgtt
     7561 gtcgccgggt ttcagggcat taccccggaa ggcgaaattg cgacgctcgg caggggcggc
     7621 tcggatacaa cggcagtggc gcttgcagca gcgcttcatg ccgaccgctg cctgatctac
     7681 acggatgtaa ccggcgtgtt tacgtccgac ccgcgctata ttccgactgc ccggaagctt
     7741 aaggctgtat cctacgatga gatgcttgaa ctggcgagcc tcggggcggg cgtcctgcat
     7801 gcaagggcgg tggagtttgc caaaaatgcg gctgtgccgc tgatcgtttg ttcgagcctt
     7861 gaaagggagg aaggcacgtt aatagaggag gaagtttcgg tggaaaaaaa tttaattgtc
     7921 cgcggcgttg catttgaaga cggcattaca agggtaacca ttttcgggct ggaaaacggc
     7981 ttccggaatt tgccggatat attcacgaca ctggcggaac accatattga tgtcgatatc
     8041 atcatccaga accggacggc ggaccataaa acatatttat cattttcgat aaaagataaa
     8101 gatctaaaag aaacggccga tcttttggaa gccgggaaag aagccctcag catcgaccat
     8161 tttgaaacgg aaaccggcct cgcaaaagtg tccatcatcg gctcgggcat ggtttccaac
     8221 ccaggcgttg cggcaaaaat gttccaggtt ctggccgacc acggcattgc gattaaaatg
     8281 atcagcacgt ccgagatcaa agtatccacc gttgtcgatg caaaagaaat ggtccgggcc
     8341 gcccggtgcc tgcatgaagc atttgaactg gatgcagtgg aacaaaatat atgaaaatat
     8401 gaaaaagcag gggagccccc tgctttttca tatttattcc tcggccgggt ctttcgcatc
     8461 ccactgcacg gtgatccgga ttttttttgc ctttttcgca acttcttcca cagcttccgt
     8521 gatcagtttt ttctgcatct ggtactgctc ggccaaaaac ccggcttcaa gcttgaatgt
     8581 cggttctgcg cctgcgccca tatccagctg ccgttcaatc atcggcccgg ataactcaaa
     8641 ttcaatatga tatttctctt cttttttgat tgacaacgtt ccccagccgg cctctttgaa
     8701 aaaagaaacc atttcttcat aggtaagcaa ctggaatttt cttgccaaat gttttcccgc
     8761 ccagtacaga atatccggcg tttccttgcc gagtatatcc ggaattaata tattgcgcaa
     8821 cagctcatat ccgaatgtgg gtaccatcag ctgttccgca acggtttgtt catttccgcc
     8881 agaagatttc acgcaattcc cctctttcta tatgctatat tatatacaaa ataaaaccgg
     8941 acttaaaagc attttttaag tatacacaaa aataaaagga actttttccg ccggtttccg
     9001 cgttatacgg ggaagtggta ccggttgcgg taaaatccga tgaaaaaaga caagccttgg
     9061 ataaaaattc cttttttatg caaaagcata tggcaaaaga gctatactga aaaaatttta
     9121 aaaaaatgga agaaagactg acaaatatga caaataaacg gcattttcag cgcaaattca
     9181 tgaatgcgtt tccttgacgt gcccatttgt cgggagtaca ataaaactgt cacataattg
     9241 ttataaaata tttatgcggg aggaagccat gcaaaatttg tcttctttgc ataaattcac
     9301 actacaaagg gggatacaat gtggctggaa atcgagagtt ttataaccgc aaactgcatt
     9361 ctttgctggg tgttgtaccc atcggcttat ttttagtcat ccacttgacc gtaaaccact
     9421 atgcggtaaa cggtgctgct gccttcaata aagcagccgg ttttatggaa aacctgccgt
     9481 tcctgctttt tgtggaagta gtattcattt atctgccgct tctgttccat gcaatttacg
     9541 gcttatacat ttcgtttacg gcatcgagca atgtcggcac gatgggctac ttccggaact
     9601 ggatgtacct attgcaaaga atcagcggtg tgctggtcct gatctttctc gtatttcaca
     9661 tctatgaaac acgcattcaa atggcgcttg gcaaggaatt gaattttgat ctgatggcaa
     9721 atcttttagc aaatcgttgg atgctcgcct ggtacataat tgggacagtg gctgccattt
     9781 tccactttgc caacggtctc tggtcgttcc tggtcagctg gggcattaca cagtcacgcc
     9841 ggtcacagca aatttccaca tatgtgatga tcgtggtctt tgtgctgctt tccgttgtcg
     9901 gcgtcagggc tttattagca tttgcataat gaaaagactc gaaaaatagc agtctactgg
     9961 tttgtaagag gcatcaagta tgaaaaggga gtgaatcaag ttggctaatg gcaaaatcat
    10021 tgttgtcggc ggagggcttg ccggtttgat ggcgactgta aaaattgcag aagcaggccg
    10081 gcaggttgat ctgttttctt tagtgccggt aaaaaggtcg cactctgttt gcgcacaggg
    10141 cggcattaac ggcgctgtca atacaaaagg ggaaggggat tcgccatgga tccactttga
    10201 cgatacggta tacgggggcg acttccttgc caaccagccg ccggtaaaag cgatgtgcga
    10261 agcggcgccg gggattatcc acttgtttga ccggatgggt gtcatgttca accgcacgtc
    10321 ggaagggctt ttggacttca ggcgtttcgg cggcacccag caccaccgca cagcatttgc
    10381 aggcgcgaca accggccagc agcttttata cgcattggat gaacaggtaa ggcgccatga
    10441 agtggacggg cttgtcacga aatacgaagg ctgggaattt ctcggcatta tcaaagacga
    10501 tgaaggcatc tgccgcggca ttgtttcgca aaacctgacc acaatggaaa tcaaagcttt
    10561 tcctgcggat gctgtcatta tggcatcagg cggccttggc attattttcg ggaagtcgac
    10621 caactcgatg atcaataccg gctcggcggc ttctattgta taccagcagg gcgcaacgta
    10681 tgcgaacggc gaatttatcc agatccaccc gactgctatc ccaggtgatg acaaactgcg
    10741 gctgatgagt gaatccgcac gcggggaagg cgggcgcatc tggacgtaca aagacggcaa
    10801 accgtggtat ttcctggaag aaaaatatcc ggcatacggg aacctcgtgc cgcgcgatat
    10861 tgcaacccgt gaaattttcc atgtctgcgt ggacttgaaa ctcggaatta acggcgagaa
    10921 catggtctat ctcgatttgt cgcacaaaga tccgcatgaa ctggacgtta aactgggcgg
    10981 gattattgaa atctatgaaa aatttgtcgg cgatgacccg cataaagtgc cgatgaaagt
    11041 attcccggcc gtccactatt ccatgggcgg attatgggtg gactataagc agcatacgag
    11101 cattccgggg ctgttcgcag caggcgaatg cgactactcg atgcacggcg cgaaccgctt
    11161 aggggcaaac tccctgcttt ctgccatcta tggcgggatg gtagccgggc ctgaagctgt
    11221 caactacatc gacgggcttg aaaagagcgc gaatgcactg ccgtcaaccg tctttgaacg
    11281 tgctgtccag gaacaggaga aaaaatggaa cgatatattg tcgcttgacg gaaccgaaaa
    11341 tgcctatgtg ttgcataagg aactgggcga atggatgaca gacaatgtga cggttgtccg
    11401 ttacaatgac cgtctgaaga aaacggacga aaagattcag gaattaatgg aaagatggaa
    11461 aaatattaat gttgtagata catcgaaatg gagcaaccag gcggcttcgt ttacacggca
    11521 gctgtataac atgctgcagc tggcgcgcgt cattacgatc ggcgccctga accgtaatga
    11581 aagccgcggc gcccactata aacctgattt tccggaccgc aacgacgaag aatggctgaa
    11641 aacgacgatg gcaaattatg accctgtgaa caatgagccg gttttcagct atgaagatgt
    11701 ggatgtatcg ctgatcaagc cgcgcgtgcg cgactacacg aagaagcact gattcggatc
    11761 gggcgaaagc ggactttttc cggcttttgc ccgggtgatt tcataaggaa agaggagaat
    11821 aaggatgggt gaacaaaaaa ccgttacatt tatcatacaa cgccaggata atccggaatc
    11881 agaaccatac gacgaaacgt ttgaagttcc gtaccggccg aatatgaatg tcatttcggc
    11941 cctgatggaa atccgccgga atccggtcaa tgccaaaggg gaaaaaacaa cacctgttgt
    12001 ttgggaaatg aactgtttgg aagaagtttg cggcgcctgt tccatggtga ttaacggcaa
    12061 gccgcgccag gcttgttcag cgcttgtgga caaactggag cagccgatcc gccttgcccc
    12121 gatgcggacc ttcccggttg taagagattt gcaaattgac cgcagccgca tgttcgactc
    12181 gctgaaaaaa gtgaaagcct ggattccgat tgacggcact tacgacttag gggaagggcc
    12241 gcgcatgccg gagaaaaaaa ggcagtgggc ttatgaactg gcaaaatgca tgacgtgcgg
    12301 cgtatgtttg gaagcctgcc cgaatgtcaa cagccgttca aactttatcg ggccggcccc
    12361 gctttcgcaa gtacggttat ttaatgcgca cccgaccggt catatgaacc gtgatgaacg
    12421 gcttgaagcg atcatggttg acggcggcct tgccaattgt ggcaactcgc aaaactgtgt
    12481 gcaagtctgc ccgaaaggta tcccgctgac aacatccatc gcagcgttaa accgtgaaac
    12541 aaccatttat atgtttaaaa aattctttgg cagtgaccat acggttgact aatgccgaaa
    12601 gtgccacatc aaagcggaaa cagtacgatg tggcgctctt tttcaaacaa aaaatgaatg
    12661 gctgttcact cattaaaagg aggcattcca ttgaaaaaac atatctctta tattgatgac
    12721 tgggaggcct gggaagaagg attttcgttt tatctcccgg tgacggtccg tttttccgaa
    12781 accgatatgt tcggccatat gaacaatacc gttccgttta tttattttga acaagcgcgg
    12841 attgaatttc tccagcagct cgggtttatg ggcgactggg caaaaagagg caccggatcc
    12901 atcccggtcg tggcggattt gcagtgtgat tttttgcagc aggttttttt caatgacaag
    12961 ctccgcattt atgtaaaagt ctcgaaaatc ggcaattcgt ccgttgactt gcactatatg
    13021 gcgaaaaatg aagcggatga aatctgtttt accgggcgcg ggacaatggt gcaaatttcg
    13081 gccgcaaccg gaaaaggaaa accgtggacg gcggaagaaa aagcgagatt cgccgacccg
    13141 caagcttatg tctcatccgg caactgaacg aaagagtcca tcccgccgta taatataaac
    13201 ttaagtgcgt gcgttgggga ttaattcgag cggagaaaag agcggcaata cgtggtattt
    13261 tttacaacaa ttgcttgcct gctttgccgt cttcgtacag gccataaaca gaatccataa
    13321 ctgccagttt acaatgccgg ataatgcttc attcttcttt tgcacagaag ggatttccgg
    13381 tatccgccct tttttgctga tttgtgctgt tccttgcctc gccaagtcac tcccggctgc
    13441 gctaaaacat aagatattgt gacaaccaaa atacccatcc ccgcggttta gagctggcga
    13501 aggcaaggag ggttatcata gttgaaggac aacgatttca cacataaacc gctgctgaca
    13561 aaaagagaaa aagaagtatt cgagctgtta gtacaagaca agacaacaaa agaaatcgca
    13621 agcgaattgt ttatcagcga aaaaacagtt cgaaatcata tttccaatgc catgcagaaa
    13681 ttgggagtca aggggcgctc gcaagctgtt gttgaattac tccgcatggg ggaattaaag
    13741 ctttgaaaca aaatcggctg caatgttgca gtcgattttg tggtttaaag aggggggaga
    13801 gaaacggaag gatctgcgga taaagcgttt actctttttg actccgattt ttacattttt
    13861 catattttta gatgaagctg gaaatttgcc ggcggtttta gtaaaatggc cacaagctca
    13921 cgacacggaa tcgttttcaa tggtgccttt aaatgaaact ccggccgaca atcgatcatg
    13981 ttagtaaaag gcggggcgtc cagacgccgg ataccgtata aaaaatcacg aggcttacga
    14041 aaacaaacgg cgttgttatc tcaaaagacg gcattaaaat tttttccaaa gccctcatga
    14101 ggcagtgtga agttttctcc aaagacgttg gacgatttgg ctttaaatca aacgctgctg
    14161 cacccaaatt tgcaaacaga cgcccatgcc gaatgaatgc ggcaccagca gaaggatgaa
    14221 agccagccgg cgcatatttt caggagagat taatagattt atccgcaaac atcgcaattt
    14281 aacggctttc cgaa
//
