LOCUS       c00037_gnlPro..        14701 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNEOGEMI_39.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 21:03:46
            Original ID  :: gnl|Prokka|LNEOGEMI_39
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 19793
            Orig. end    :: 34494
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14701
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[29793:30621](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..10828
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14701
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14701
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             63..572
                     /locus_tag="ctg37_23"
                     /transl_table=11
                     /translation="VLHDHLNVLTLFALSGEIVGRKKLQKMVYIAKQMGYPFNERYHFH
                     RYGPYSDELTVRLEELCNLGFLIESEEDKGHYSQYRYTLSPQGQAFLEMYHPPVAGYKD
                     LCQALNNQSARFLELLSTILYFSDLEEGARREKIRQLKKKQNYSDDDFDEAHTYLQKLA
                     QLVASA"
     CDS             678..881
                     /locus_tag="ctg37_24"
                     /transl_table=11
                     /translation="VEPLVLSFVLMLLLFAAGIPLLLILILHYPLIGACVIAFISINWF
                     IAARLHRKHERMQHAGHDKNGL"
     CDS             complement(980..1513)
                     /locus_tag="ctg37_25"
                     /transl_table=11
                     /translation="MSYQTHEPYGTNSQSARTPTQHLAWRETLELHELTAFQSIVLMRC
                     KLSLAKVSDPVLQNLYLESIQLLEKNLKELLPFFSYAPRHENVAAPHPDSGFWAGDLLG
                     AAKTAVRNYAIAITETATPVLRNVLSKQLQGAIQWHANVYSYMNERSYYPSYNLGQLLE
                     NDITNAHRAIQMDY"
     CDS             complement(1802..2026)
                     /locus_tag="ctg37_26"
                     /transl_table=11
                     /translation="MYSRKERGFFMPIVTVQLLEGRTDEQKRALVEKVTDAVSETTGAP
                     KERVSIIISEMKPNDYGVAGKRPSDQNEQ"
     CDS             complement(2058..2741)
                     /locus_tag="ctg37_27"
                     /transl_table=11
                     /translation="VALRKSNGKQGRFKKTALLFVAAAFIAFGLWLTTTTGFKLAYGYF
                     LYKIGAHSETETVAAPVEEAPEAIPAYENDRQDVASWQPEIGEQMGTLTIPKIDATLPI
                     IHGTNEDELDKGVGHFADSVLPGEKDNSVLSGHRDTVFRKLGEVGEGDELIVETRSGVY
                     TYKVHTVRIVDEDDRTVIVPTEEAQLTVITCYPFDFIGAAPDRYVLVADLIDQDVYETL
                     ALFPK"
     CDS             complement(2744..3877)
                     /locus_tag="ctg37_28"
                     /transl_table=11
                     /translation="MKKSLFTAIFTLLFLFSAPAASLAHGFDNEEFTAYLEDVGVSEKD
                     LAEHLMYWWEGTTFYDFTDVSELAEFLGPRLTEEGINEIAAEFDLTRQELDELLEEWLG
                     LPPSDLLFYNTFYMVVHVIITLEDEWGNEPYYPDFSGFLSEFSLSDEEEWALYEHFWYI
                     QETNPNLSAELDDLKQRAYAFDGFESIRELSAADVAELFAIGEKAISVLDLHPKYYLDR
                     VGEDPKPISYKELMSGNAIKGYDLLVELYDADGSFLADFYITAEMFNSHFVKKIVDDVT
                     QIDKGLKDKPKKPSLESALPGKDEAPLPAKAGNDANHNDGGKKAERDENGKVTKTANGA
                     KMPKTATNYPLYMLIGIGMSLAGVLIFRRLLREKKVA"
     CDS             4152..4709
                     /locus_tag="ctg37_29"
                     /transl_table=11
                     /translation="VDLLNNDNLKKAKKKSSSFTILSNDSTDGHGGYGAGVINLDNVTP
                     LFIDIEEKEAFVDMGALHARSAVEKRVKFIADEEAVPKEGLKRYWLVWVTIDTKDKKPY
                     YSGVAACYMTVNKQAKRGYKSMPEHVNHMDKSLKGKLVVSQMDDSSRQVLKAFLKNHNE
                     EMWNHSSQELHEALESSENVNN"
     CDS             complement(4836..6623)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_30"
                     /sec_met_domain="Peptidase_M3 (E-value: 1.1e-71, bitscore:
                     233.6, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSTYKSRKDVPEHEKWDLTDLYADEQAWQADVDECYQLADTLSQF
                     DGAIQDAKSLLDFLETQEKLSFTLRKVFAYTMFLSDIDTRDAHAQKLSAKATQLSVKVS
                     ESTSFFMPFLLSLSEETLRAYISAEKKLGYFEDELWKSFRFKKHVLTKEKEELLSQLGA
                     TFQAPGDTYNMLNNADIQFGTVTDDNGQQVQLTRGMYSKLIEDEDRNKRKEAYKAYYKP
                     YVELNNTIATTLSAEIKTNVTLAKVRQYESALHKALFADNIEQSVYDQLIDAAKANIAP
                     LHEYARLRKQKLGLDELRQYDLNAPIVPGVKAEISYEEAYETMLKALKPLGDDYIAKLK
                     EFKEKRYIDVRETPGKRSGAYNMGVYGVHPFVLLNHHDDLNSLFTLVHEMGHAMHSYYS
                     SKYQPQITANYRIFVAEVASTVNEVLLINYLLKETSDKKMRAYLLNHFIEQFRGTFFTQ
                     VMFADFEKQTHERAEAGEPLNAESLNELYEQLFRTYNGPDIVFDDEVKYGWSRIPHFYR
                     AFYVYQYATGFASAIKIATAILDGEEGALDAYMTFLQSGSSDEPLELLKKAGVDLTTPE
                     PVQAAMARFSALVEELKQL"
     CDS             6800..7618
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_31"
                     /sec_met_domain="Acetyltransf_1 (E-value: 1.1e-15,
                     bitscore: 49.3, seeds: 223, tool: rule-based-clusters)"
                     /sec_met_domain="Acetyltransf_10 (E-value: 1e-07, bitscore:
                     23.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSEQKKAIQSLQEKVEQADGIKLKLNWDLLEGERSLNGTEDYF
                     YYNEKGELLGYLAVYFFGNKMECCGMVDPAARRRGIGRMLLDQAASDWQGKTKQFLLNS
                     PTDSESGIAFMKAVGAEYAFTEKQLVCREVPIPYTKKGIRIRPAVSNDEERIYELDAEG
                     FHMTKDEAKALHHNNPTWVTYMIEEDNHPVGKLSISRQDQESWIYAFVLTKEKRGQGIG
                     RAALTDIVHREVSNGKTVWLDVVCTNEAALTLYHTCGFTEVGSQTYYTLK"
     CDS             complement(7714..9840)
                     /locus_tag="ctg37_32"
                     /transl_table=11
                     /translation="MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGP
                     PPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLAEMSPYLLQATIAIEDRKFYSHYGFD
                     LKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMNFSK
                     DEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDL
                     EKAKSRQELILDSMVGEGMIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLH
                     NEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPDNGLQVALIAMDPRNGEVKAL
                     VGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGRED
                     YAPSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSL
                     ALGAQPVTVLDIANAYAALADGGKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAF
                     VLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRDSWMVGYTPQLVTAVWV
                     GFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDA
                     CPNGRTTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSG
                     PTILDEGEESPATE"
     CDS             10001..10828
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_33"
                     /sec_met_domain="Spermine_synth (E-value: 9.9e-74,
                     bitscore: 238.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 4.5e-23,
                     bitscore: 72.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFTEKQTERFGITMKIKRTLHTEKTDFQQLDMVETEEFGNML
                     LLDGMVMTTEKDEFVYHEMVTHVPLFTHPNPKHVLVVGGGDGGAIREILKHPSVEKATL
                     VDIDGKVIEYSKTYLPTIACALEDERVDVKVADGFMHIAQSANEYDVIMVDSTEPVGPA
                     AKLFERGFYEGIFKALKEDGIFVAQTDNPWFHQELVSNVYKDVKEIFPITRLYTANIPT
                     YPSGMWTFTIGSKKHDPLAVEATRFHDVQTKYYTPDIHRAAFVLPKFVQDLLK"
     CDS             10840..11718
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_34"
                     /sec_met_domain="Arginase (E-value: 2.2e-81, bitscore:
                     264.6, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIMSRASYEEADAVIYGMPMDWTVSFRPGSRFGP
                     ARIREASLGLEEYSPYADKHLEEINYFDAGDIPLPFGNAARSLDIVEEYVDSLLADGKF
                     PLGLGGEHLLSWPIFKAMYRKYPDLAIIHIDAHADLREQYEGEALSHSTPIRKACELIG
                     AENVYSFGIRSGMREEFAYAKEAGMHLYKFDVAEPLKNVLPHLSGRPVYITIDIDVLDP
                     AHAPGTGTAEAGGITSKELLEAQMLLSQADIQIVGADLVEVAPAYDPTEQTAIAASKFV
                     REMLLGWVHKR"
     CDS             11834..12265
                     /locus_tag="ctg37_35"
                     /transl_table=11
                     /translation="MKRKVKISFQTTTFIQGQQPDAFSFDTEGDLYIKGSASYLRFKET
                     HAHKQDVFSTMKWDGRELMLIRQGTIIMRQSFLAKEETYGRYVTPEASWETKARTDTLL
                     VQLPTGAKQKGRIYVRYQFFLQGQLTGEHEIRLAVERIE"
     CDS             12477..14147
                     /locus_tag="ctg37_36"
                     /transl_table=11
                     /translation="MNHMERKKEQLRVEVRRAVLQAELATESEVPSVLLEAPKDKAHGD
                     FATNIAMQLARIAKKAPRAIAEELVANFDRKQAGIEKIEIAGPGFINFFLDNGYLRELI
                     PQVLTEKDDYGSSDVGQGEKVLIEFVSANPTGDLHLGHARGAAVGDTIANIMDKAGYKV
                     SREYYINDAGNQIENLAASLNARYLQVLGEDQPMPEDGYHGQDIIDIAKQLVDEAGDQY
                     RQLDEKERLAFMREYGLKKELEKIKQDLNAYRVEFDKWFSETSLYESGQVERGLQVLKD
                     KNETYEKDGATWLRSTAYGDDKDRVLVKQDGTYTYLTPDISYHLDKFDRGHDRLIDVLG
                     ADHHGYIPRMRAAIQALGYDPARFNVQIIQMVSLFQGGEKVKMSKRTGKAVTLRELMEE
                     VGVDATRYFFAMRSPDTHLDFDMDLAVSKSNENPVYYIQYAHARVCSILRQGEELGIPY
                     SANTDLSPIASEKEYELLKAIGEFPGAVAEAATKQIPQRIANYAYDLAQALHSFYNVTR
                     VIDTENKDLSAARLALMKATQMTIKNALALLGVEAPEKM"
     CDS             14150..14626
                     /locus_tag="ctg37_37"
                     /transl_table=11
                     /translation="MDTLWWLVIAVFFIASFVGLIVPIIPSVLVLWGGFLVYVFALEGS
                     LSVVFWVGMAVLTVFLLVVDLLANMAFVKRTGGSKWGERAALVGVIVGAFVVPPFGLII
                     VPFVLVLIAELLQKQPFEKAVRIAFASFLAFISGTLAKAVVQIVMIAWFLIEVL"
ORIGIN
        1 ataaggacat ccgagacagc attcaatcat tacttgcgac tacataaagg aggaagactg
       61 ccgtgctgca tgaccattta aatgttctga cgctgtttgc gctgtcaggt gaaattgttg
      121 gcagaaagaa attgcaaaag atggtctata tcgcaaaaca gatgggctat ccatttaatg
      181 agcgttacca ctttcatcgg tacggccctt attcggacga gctgacagtg cgattagaag
      241 agttgtgcaa ccttggtttt ttaatcgaga gcgaagaaga caaaggccat tattcacaat
      301 atcgctatac gctttcgccc caagggcaag cgtttttgga aatgtaccat ccccctgttg
      361 ccggctacaa agacttgtgc caagcattga acaaccaatc agctcgtttt ttagagctat
      421 tgtctaccat cctttatttt agcgatttag aagaaggggc aaggcgtgag aaaatacgtc
      481 agctcaaaaa aaagcaaaat tatagcgatg atgattttga tgaagcccat acatacttgc
      541 aaaaactggc ccaacttgta gccagtgctt aaatagaatc gctcatagat tttacatgtt
      601 gtttgacaag gattttgtag atatggcgcc ggtttagcgc tacactagaa aagtgaaagg
      661 aattcaagga aagaagggtg gaaccactcg tgctcagctt tgttctcatg ctccttttat
      721 ttgcggctgg gattccgttg cttctcattt tgatactcca ttatccgttg atcggcgctt
      781 gtgtaatcgc ctttatttct ataaattggt tcattgccgc acgcctccac cgtaaacacg
      841 agcggatgca gcatgcaggc catgacaaaa acggactgta atccgatgat acagcccgtc
      901 ggccatgcgt tttgattgca tggctttttt cttgttttgt cttggaccac aacatgagag
      961 caaagatgtg attacaccat taatagtcca tttgtatcgc gcggtgagcg ttggtaatgt
     1021 cgttttccag caattggcca aggttgtaag acgggtaata actgcgctcg ttcatataag
     1081 agtaaacatt ggcatgccac tgtattgccc cttggagttg cttacttagc acattccgca
     1141 gcacaggtgt ggctgtttcg gtaatagcga tcgcataatt acggacagct gttttggctg
     1201 cacctaataa gtcgcctgcc caaaaacctg aatcgggatg tggagctgcc acattttcat
     1261 gcctcggtgc atacgaaaaa aacggcagca actctttaag gttcttttca agcagctgaa
     1321 tcgattctaa ataaaggttt tgtaagaccg ggtccgatac tttcgcaagc gacagtttgc
     1381 atctcattaa aacaattgat tgaaaagccg ttaattcatg gagctcaaga gtttcgcgcc
     1441 aggccagatg ttgggtgggt gtgcgcgcgg attggctgtt tgttccatat ggctcgtggg
     1501 tttgataaga catgaatatc ctcctttaca gttactaaca ctgtattcca aaaaaggaaa
     1561 ttggtctctt gtcccgtagc catcttttcg tattaaagaa ccgatatatt cgtctaaagg
     1621 ttagaactgg cgttggagtg cgaggatttc gagaaagctt gaatgagcgt aggcgatacg
     1681 ctttttagcg ggtctttgtt tcagcatagg aaatatgtga gtatgttagt gacgtcttca
     1741 attggagacg gaccgtcgtt aaggacggcc cgccttagat tgtaggaaaa ggcacccatt
     1801 cttactgttc gttttgatcg cttggccgtt ttccagcgac tccgtagtcg tttggtttca
     1861 tttcgctaat gatgatggaa acacgttctt ttggtgcgcc tgttgtttca ctaacggcat
     1921 ctgttacttt ttcaactaat gcgcgttttt gctcatctgt acggccttca agcagttgaa
     1981 cggttacaat tggcataaaa aagccccttt cttttcgaga atacattcag tataccaaaa
     2041 gaaaggggct gttttgatca tttaggaaaa agcgcgagtg tttcataaac gtcttgatcg
     2101 attaaatcag cgacaagcac ataacgatct ggggcagcgc caataaaatc gaatggataa
     2161 caagtgatca ccgtcagctg tgcttcttcc gtcggaacaa tgacggtgcg gtcatcttca
     2221 tcgacgatcc gtaccgtatg caccttatac gtgtagacgc cacttcgtgt ttcgacaatg
     2281 agttcatccc cttcgccaac ttctcctagt ttgcggaaca cggtatcacg gtgtccagat
     2341 aaaacggagt tgtccttttc tccaggaaga acactgtcgg caaagtggcc gacgccttta
     2401 tccaattcat cttcatttgt cccatgaata atcggaaggg tcgcgtcgat ttttgggatc
     2461 gttaatgtcc ccatttgttc gcctatttct ggctgccagc tggcaacgtc ctggcgatcg
     2521 ttctcgtagg ccggtatagc ttctggtgcc tcctcaactg gggcagcgac cgtttccgtt
     2581 tcgctgtgcg ccccgatttt atagagaaag taaccgtacg ccagcttaaa gcctgtcgtt
     2641 gttgtcaacc aaagtccgaa agcaataaag gcggcggcga cgaaaagcag agctgtcttt
     2701 ttgaaacggc cctgctttcc atttgattta cgaagagcca cttttaagcg accttcttct
     2761 cacggaggag gcggcggaag ataaggacac ctgcaaggga cattccgatg ccgatcagca
     2821 tataaagggg atagtttgtt gctgtttttg gcattttggc accatttgcc gtttttgtca
     2881 ctttgccgtt ctcatcacgt tccgcttttt tgccgccgtc gttatgattg gcgtcgtttc
     2941 cagcttttgc cggaagcgga gcttcgtctt tgccaggaag cgccgactcc aatgatggtt
     3001 tttttggttt atcttttagg cctttatcaa tttgagtgac gtcatcaacg atttttttga
     3061 caaaatgaga attgaacatc tccgcggtaa tataaaaatc ggccaagaat gatccatccg
     3121 catcgtatag ctcgaccaat aagtcgtacc ctttaatcgc gttgccgctc attagctctt
     3181 tatagctaat tggctttgga tcttcgccaa cgcggtcaag gtaatacttt ggatgaaggt
     3241 caaggacaga tattgctttt tcgccaatag cgaacagttc agcaacatcg gcagccgaca
     3301 gttcgcggat tgattcaaag ccgtcaaatg cgtacgcacg ttgtttcaag tcatcgagtt
     3361 cggcggataa gttcggattg gtttcctgaa tataccaaaa atgctcataa agcgcccact
     3421 cttcttcatc acttaaagaa aactctgaca aaaatcctga gaaatcaggg taatatggtt
     3481 cgttgcccca ttcatcttct aatgtgataa tgacatggac aaccatgtaa aacgtgttgt
     3541 aaaacaataa gtcgcttgga ggcaggccga gccattcttc aagaagctcg tccaactctt
     3601 ggcgagtaag gtcaaattca gcagcgatct cattaatgcc ttcttctgtt agccgtgggc
     3661 ctaaaaattc ggcaagctca cttacatcgg taaaatcata aaaagtcgtg ccttcccacc
     3721 aatacatcaa gtgttcagct aagtcttttt cgcttacgcc aacatcttct aaataagccg
     3781 taaactcctc attgtcaaat ccatgggcaa ggctggccgc tggagcggaa aaaagaaaga
     3841 gtagagtgaa aattgctgta aataacgact tcttcatttt gttcctccca tattcaattg
     3901 tcatttttat ccgtgcatat gaattatata aacatgatcg cttaatgtca cgacttattt
     3961 tcatatttta taaaaatttt ataatagagg ctgcttttgc caaaaaacga cgaaattcgc
     4021 ttgtctgtgt tgaagagggc aacggcgagg aggccgccac tttttctcaa aggcagagag
     4081 gatgaatggg cgtggcgttt tatgatacac tagtgtttag ctaaaatgaa atttgggagg
     4141 gccgataaaa cgtggatttg ctcaataatg ataacttaaa gaaagcgaag aaaaagtctt
     4201 ccagttttac gatattaagc aatgattcaa cagacggaca cggcggttat ggcgctgggg
     4261 tcatcaatct cgacaatgtg acgccgctat ttattgatat tgaagagaaa gaagcgtttg
     4321 tggatatggg tgccctccat gcccgctcgg cagttgagaa gcgtgtgaaa tttatcgctg
     4381 acgaagaggc ggtgccaaaa gaagggctca aacggtattg gcttgtgtgg gtcacaatcg
     4441 acacaaagga taaaaagcca tactatagtg gagttgcagc ctgttacatg acagtcaaca
     4501 agcaggcgaa acggggatac aagagcatgc cggaacatgt gaaccatatg gataaatcgt
     4561 taaaaggcaa attggttgtc agccaaatgg atgattcgtc acgccaagtg ctaaaggcgt
     4621 ttttgaaaaa ccataatgaa gaaatgtgga accattcttc gcaggaactc catgaggccc
     4681 ttgaatcaag cgaaaatgtg aacaactaat gaacaagttg ccgaaaatct tgtactcttt
     4741 tttcgcttcg gctacgctag agacatggat gaacatcctg acgataagta ctaggacaaa
     4801 aaagcagcgg aagggctctc cttccgctgc tttttttata gctgttttag ttcctccacg
     4861 agtgcagaga agcgcgccat cgcggcttgc actggctcag gcgtcgttaa gtcgacacct
     4921 gcttttttta gcagttcgag tggctcgtcg gaactgccgc tttgcaaaaa ggtcatataa
     4981 gcgtcgagtg cgccttcttc accgtctaaa atggctgtgg cgattttgat tgctgaagca
     5041 aagccagtcg catactggta aacgtaaaaa gccctgtaaa aatggggaat gcgcgaccag
     5101 ccgtatttga cttcgtcatc aaacacaatg tctgggccat tgtaggtacg gaacaactgt
     5161 tcataaagct catttaagct ctctgcatta agcggttcac ctgcttccgc tcgttcgtgc
     5221 gtttgctttt caaaatcagc aaacatcact tgtgtaaaaa aggttccgcg gaattgctca
     5281 ataaaatggt tcagtaaata ggcgcgcatt ttcttgtcgc ttgtttcttt cagcaaatag
     5341 ttaattagca acacttcatt caccgtggaa gcgacttcag cgacaaaaat tcgataattg
     5401 gccgtaattt gtggttggta tttgctggaa tagtagctgt gcatggcatg gcccatttca
     5461 tgaacgagtg taaacaagct gtttaagtca tcatggtggt tgagcaatac gaaaggatgg
     5521 acaccgtaga cgcccatatt gtaagcacca gaccgttttc ctggtgtttc gcgcacatca
     5581 atgtaacgct tttccttaaa ctcttttaat ttggcgatgt aatcgtcacc aagaggcttt
     5641 agcgctttca gcatcgtttc atacgcttct tcatatgaaa tttccgcttt cacaccagga
     5701 acaattggcg cattcaaatc atattgacgc aattcatcga ggccaagttt ttgtttgcgg
     5761 aggcgcgcat attcatggag cggtgcaata ttcgctttag ccgcatcaat caattggtca
     5821 tagacgcttt gctcaatgtt gtcggcaaat aaagctttat ggagagccga ttcgtattga
     5881 cgaactttcg ccaatgtgac atttgttttg atttctgctg acagcgtcgt tgcaatcgta
     5941 ttgtttaatt ccacgtacgg cttgtagtaa gctttgtatg cttctttccg cttgtttcga
     6001 tcttcgtctt cgatgagctt tgaatacatg ccccttgtca gttgcacttg ctggccattg
     6061 tcgtctgtca ccgtgccaaa ctgaatatca gcattgttca gcatattgta tgtgtcgcca
     6121 ggggcttgaa aagttgcgcc taattgcgac aaaagctctt ctttttcctt tgtcagcaca
     6181 tgttttttaa agcggaatga cttccacaat tcgtcctcga aatagccaag tttcttttcc
     6241 gcagaaatgt aagcacggag cgtctcttcg cttaaactta aaagaaacgg catgaagaag
     6301 gaggtggatt cactcacttt tacgcttagt tgtgtcgctt tggcacttaa tttttgggca
     6361 tgggcgtccc gtgtgtcaat atcggataaa aacatcgtgt aggcgaaaac ttttcgcaac
     6421 gtgaaggaga gcttctcttg tgtttctagg aaatcgagca agctttttgc gtcttgaatc
     6481 gcgccatcaa attgacttaa cgtgtccgct agctgatagc actcgtctac atcggcctgc
     6541 cacgcttgtt cgtccgcata aaggtcggtt aagtcccatt tttcatgttc aggtacatct
     6601 ttacgggatt tgtatgtact caagaaaatc actccttgca tgttttttcg ttctagtgta
     6661 gcacttatcg ctgaaaatat gttcgtttct gcttttttgt atgaattttt gctggcggtg
     6721 gcaaaaatcg attcataaaa gttataaaaa taacggtcac gttctatgtt atactaagga
     6781 aaaaggcggt gacatgatca tgctctcgtc agagcaaaaa aaagcgattc aaagccttca
     6841 ggaaaaagtg gaacaagctg acggcattaa gcttaaatta aattgggacc tcttagaagg
     6901 tgagcgttcc ttaaacggca cggaagacta tttttattat aatgaaaaag gagagctgct
     6961 tggttattta gcagtttatt tctttggcaa taaaatggaa tgctgcggta tggtcgatcc
     7021 cgctgcaaga aggcgcggca taggtcgaat gcttcttgat caagccgcct ctgactggca
     7081 aggaaagacg aaacaatttc tgttgaatag cccgactgat tcagaaagcg gcatcgcgtt
     7141 tatgaaggca gttggagcgg agtacgcgtt tacggaaaag cagctcgtat gccgagaagt
     7201 tccgattcct tacacgaaaa aaggaattcg catccggccg gcagtatcaa acgatgaaga
     7261 gcggatttat gaacttgatg cagaagggtt ccatatgaca aaggacgaag cgaaggcgct
     7321 tcatcataat aaccctacat gggttacata tatgattgaa gaagacaacc acccagttgg
     7381 caagctcagc attagccgcc aagatcagga aagttggata tatgcttttg ttttaacaaa
     7441 agagaagcga ggacaaggca taggccgggc agctctgact gatattgtcc accgtgaagt
     7501 ctcgaatggc aaaacggtat ggctggatgt cgtttgcacg aacgaagcgg ctctaacgtt
     7561 gtatcataca tgcggtttta ctgaggttgg ttcccaaaca tactatacat taaaatagat
     7621 tggcgcaaat ggtcgtagct gcgagcgttt gtcgataacc tcactcagac tgatagaagc
     7681 tgagagctgc acaaacgtgc agctcctttt cgcttattca gtggcgggac tctcttcacc
     7741 ttcatcaaga atggttggcc cagagggatc actcgggtca ccgtcttcaa tgctaaacca
     7801 tttaaaaaaa cgtttgaaaa agcctggatc tttcgtttct ggctcttctt gtaagtcttc
     7861 ggctgcctct ggctcagcgc aagtatttac aggagcagtt cctgctaaaa agtaagtcgt
     7921 gcggccatta ggacaggcgt cgctcgttaa caacccagtg tgggggtcga tgtcaacggc
     7981 ttcaacccct ggcggttctt taaacggaag ctttagttca ttggccatcg ctgcttccat
     8041 aaagtccgcc caaatccgtt tcgagatttg cccttcaacc gattgattga tgtctttgtc
     8101 tttatcaaaa ccaacccaca cagcagtaac aagctgtggt gtatagccaa ccatccagct
     8161 gtcccgaggt gttgatccag attttccggc tgtcgggtgc gttagctgtg cggctacgct
     8221 tgcaccggta accgatgtgt agctgtttag cgccggttca aatacgccgc gcaacatatc
     8281 ggtcagcaca aaggctgtat cttcacggag gacttggcgg acaggcggtt tttgttcgta
     8341 gactttgttt ccctcgccgt cacgcacttg gcgtatgaat accggttccc gttgttttcc
     8401 tccgtcggct aaagccgcgt aagcattggc gatatcgagg acggtgacag gttgtgcccc
     8461 taaagcaagg gaagggcggt tttcaaatgt accaagtccc agtttttcag agacatttac
     8521 tagttcgtct gtgccaatag ataaatgcgt tttcatcgca taaatattgt ctgagtaagc
     8581 gatggcttca agcattgtaa taaaatcatt ggcgtaaatg tcgttgtagt tactcggagc
     8641 gtagtcttct cgaccatcat cataggaaaa ggatgtcgct tcacttaaaa acgtcgatac
     8701 gggcgtaaaa ccgttctcga gtgcagcgta atacaaaaat ggtttaatgg tcgacccagg
     8761 gttgcgcatg gcctgtgtag cgcggttata ggaactttca ttgtaatctg tgccgccgac
     8821 aagcgccttt acttccccat tgcgtgggtc catggcgatc agggcgactt gcagcccgtt
     8881 gtcgggcata tgcttttcga ccaaatcttc ggcctgttgc tgcaaggcgg gatcaagcgt
     8941 cgtctcaatg atcagtccac ctgtgtcaac ggccgcttcg tccatttgcg cttcattgtg
     9001 tagcagcgct ttaacatggt cttgaaaata aggcgcgatt tcttcttcct ctttatcagc
     9061 ttcgtccgca aaaaccagtt tttccgcttt tgctttgtct gcttctgcct cctcaatcat
     9121 gccttcccca accatgctat ccaaaatcag ctcttgcctg cttttcgctt tttcgagatc
     9181 attcaatggc gaatagtagc ttggtccttt cggaatgcct gcaagcattg ccgcttctgc
     9241 caatgacacg tcttttgccg atttcccaaa gaaatgctgt gcagctgctt caactccata
     9301 ggcgccatgc ccataataga cggtgtttaa gtaaccagct aaaatctcgt cttttgaaaa
     9361 attcatctcc agacggagtg cgtaaagcag ctcattccat ttccgcatat aagttttttc
     9421 gtggctcaaa taaaggttgc gtgcgtattg ttgtgtaatg gtgctcgccc cttgtgcttt
     9481 tgagccagat tgcaaattgg caaggagcgc tccgccgatt cgtttaaggt caaagccgta
     9541 atgggagtaa aactttcggt cttcaatcgc gattgttgct tgcaacaaat aaggtgacat
     9601 ttctgctagc gggagagaaa agcggttttg accggcttct tctttcccca taaccgttcc
     9661 gtctgccgcc aaaaactgtg ttgtttgcac ggcgtcaatt ggtggggggc cttgcatgcg
     9721 cgtataagat aataatagaa taatgcctaa cgcgatgacg ataagagaaa gcaacaaaag
     9781 ccgccaaata agcctgattt tgcgaaagcg tttccgcttt ttgcgcgtaa ctgtctgcat
     9841 gacttttcat cctttccccg gcaacttgtt tagtatacag tttgggaaaa aagcggtttt
     9901 tttaaacctt gttgtctttg caattcgtaa cgcatccgct atacttgctt tgggcgtaag
     9961 gaaaaatcat atgcctagcg agatatgaga ggtgacaagc atggagtttt ggtttacaga
    10021 aaaacaaaca gaacgatttg gcattacgat gaagataaaa cggacgcttc acacggagaa
    10081 gacagacttc caacagcttg atatggtgga aacggaagag tttggcaaca tgttgcttct
    10141 tgacggcatg gtaatgacga cagaaaagga cgaatttgta taccatgaaa tggtgacaca
    10201 tgtcccttta ttcacgcacc cgaacccaaa gcatgtcctt gtagtaggtg gcggcgatgg
    10261 cggggcgatc cgagaaattc ttaagcatcc ttctgttgaa aaagcgacgt tggtcgatat
    10321 tgatgggaag gtcattgaat actcgaaaac ctatttgccg acaattgcct gtgctttaga
    10381 agatgaacgt gttgacgtga aagtcgctga cgggtttatg catattgccc aatcagcaaa
    10441 tgagtatgac gtgattatgg tcgattcgac ggagcctgtc ggaccagctg ctaaactgtt
    10501 tgagcgtggg ttttatgaag gaattttcaa agcgttaaaa gaagatggca tttttgttgc
    10561 gcaaacggat aacccatggt tccatcagga actagtgtct aatgtgtaca aagacgtaaa
    10621 agagatcttt ccgattaccc gtttgtacac cgccaatatt cctacctacc caagcggcat
    10681 gtggacgttt acgatcggtt ctaaaaaaca cgatcctctt gctgtagaag caacgcgctt
    10741 tcatgatgtc caaacgaaat attatacgcc agacatccac cgtgccgcgt ttgtactgcc
    10801 gaaattcgtc caggacttac ttaaatagga ggcttttaca tgcgatttga cgaggcatac
    10861 tcaggcaaag tgtttattat gagccgcgcc agttatgaag aggcagatgc cgtcatttac
    10921 ggcatgccga tggactggac cgtttccttt cgtccaggtt cccgttttgg cccggcgcgg
    10981 atccgtgaag cttccttagg gcttgaagaa tacagccctt atgccgacaa gcatttggaa
    11041 gaaatcaact attttgatgc aggcgacatt cctttgccat ttggcaatgc agcgcgaagc
    11101 ctagacattg tggaggaata cgttgattcc cttttagcag atggcaagtt ccctctaggc
    11161 ctgggcggcg aacatttgct gtcatggccg atttttaaag cgatgtaccg gaaatatccc
    11221 gacttagcga tcatccatat tgatgcccat gctgacttgc gcgaacaata tgaaggcgag
    11281 gcgctatccc attctacgcc gattcgcaaa gcgtgtgagc taattggagc cgagaacgtt
    11341 tattcatttg gcatccgctc aggcatgcgt gaggaatttg cttacgcaaa ggaagcaggt
    11401 atgcatctct ataaatttga cgtggcagag ccgttaaaaa acgtgctgcc ccatctatca
    11461 gggcggcccg tttacattac gattgacatt gatgtattgg atccggcaca cgcgcctggc
    11521 acaggcacag ctgaagctgg ggggattacg tcaaaagagc tgctcgaagc gcaaatgctg
    11581 ctctcccaag cagacattca aattgtaggc gctgatctcg tggaagtagc accagcttat
    11641 gatccgactg agcaaacagc cattgctgcc agcaagtttg tgcgtgagat gcttctcggt
    11701 tgggtgcata aaagataaag aaacaagaga tgcagattgc accccgtccc taaacccagt
    11761 aaaataggaa aaagaacgcg cttcgcggat ttgtgtgcgg ctagcagatc atatagaatg
    11821 gatgttttga tgaatgaagc gaaaagtgaa aatctctttt caaactacaa catttataca
    11881 agggcaacag ccggatgcgt tctcgtttga taccgaaggc gacctttata taaaagggag
    11941 tgcctcgtat ttgcgcttta aagaaacaca tgcccataaa caggatgtat tttcaacgat
    12001 gaaatgggac ggccgcgagc tcatgctcat ccggcaaggg acgatcatta tgcggcaaag
    12061 ttttcttgca aaagaagaaa cgtatggacg gtatgtcacg cctgaagctt catgggaaac
    12121 aaaagcgcgg acagatacat tgcttgtgca gctgccgaca ggagctaaac aaaagggcag
    12181 aatttatgtg cgctaccaat tcttcttgca aggccagcta acgggagagc atgaaatccg
    12241 attggcagtc gaacgaatcg aataggtcag aacaggataa tacaaggaat gtgccaatca
    12301 tccttgtatt tttttgctct gaaaggcaga agcccttgaa gctcgttgcc tgattcggct
    12361 aaactacgga tagacaagtc ggtttcagcc attttctaat ccatagcgac aaacgtggat
    12421 ggggagcact tgatggaatg aataccaatt agagacaaat aaggagccta tgaagaatga
    12481 accatatgga acgcaaaaaa gaacagttgc gcgtggaagt gcgccgtgcc gttttacagg
    12541 cggaacttgc tacagaatca gaagtgccgt ctgtcctttt ggaagcgcca aaggacaaag
    12601 cgcatggcga ctttgccacg aatatcgcca tgcagcttgc acgaatcgct aaaaaggcgc
    12661 cgcgggctat tgcagaagag ctagtggcca actttgaccg taaacaggca ggcattgaaa
    12721 aaatcgaaat cgctggccct ggctttatta acttcttttt ggataatggc tatttgcgtg
    12781 agttgatccc gcaagtcctc actgaaaagg atgactacgg cagcagtgac gtggggcaag
    12841 gcgagaaagt gttaattgaa tttgtgtcag ccaatccgac aggagacttg catttaggcc
    12901 acgcccgtgg ggctgcagtc ggcgacacca tcgccaatat tatggataaa gccggctaca
    12961 aagtgtcacg ggagtattac attaatgacg caggcaacca aatcgaaaac ttggcagctt
    13021 ctttaaatgc ccgctattta caagtgctcg gagaagacca accaatgccg gaagacggtt
    13081 accacggcca agacattatt gatattgcca agcagcttgt cgacgaagcg ggcgatcaat
    13141 atcgccaact cgatgaaaaa gagcggttag cattcatgcg cgaatatggc ttgaaaaaag
    13201 agcttgaaaa aattaaacaa gatttaaacg cataccgcgt tgaattcgac aaatggtttt
    13261 ctgagacgtc tctttatgaa tcggggcaag tcgagcgggg gttgcaagtc cttaaagata
    13321 aaaatgaaac atacgaaaag gatggggcga catggctacg ctcaactgct tatggcgatg
    13381 acaaagaccg ggtgcttgtg aaacaagacg gtacgtatac gtacttaacg ccagacattt
    13441 cgtaccatct tgataaattt gaccgtgggc atgaccgttt aattgatgtg ctaggtgcgg
    13501 atcatcacgg gtacattcca agaatgcggg cggcgattca agcgcttggt tatgatccgg
    13561 ctcggtttaa cgtacaaatt atccaaatgg taagcctgtt ccaaggcggc gaaaaagtca
    13621 aaatgagcaa gcgcacgggc aaagcggtga cgttgcgtga attgatggaa gaggttggcg
    13681 ttgatgcgac acggtatttc tttgcgatgc gtagcccaga tactcatctt gatttcgata
    13741 tggacttagc tgtgtcaaag tcaaatgaaa accctgttta ttacattcaa tacgcacatg
    13801 cacgggtatg cagcattctt cgccaaggag aagagctagg catcccttat agtgcaaaca
    13861 cggatttgtc gccgatagca agcgaaaaag aatatgagtt gctaaaagca attggcgagt
    13921 ttcctggtgc tgtggcagaa gctgcaacaa agcaaattcc acagcgcatt gctaattatg
    13981 cctatgattt ggcgcaagcg ctccacagtt tttataatgt gacgcgcgtc attgatacag
    14041 aaaacaagga cttgtctgca gcgcgtttgg cattgatgaa agcgacgcaa atgactatta
    14101 aaaatgcgct cgccctgcta ggggtggaag cgccagagaa gatgtagcca tggatacatt
    14161 atggtggctg gtgattgccg tttttttcat tgccagtttt gttggtttaa tcgtaccgat
    14221 tattccctct gtcctcgtgt tatggggcgg ttttctcgtc tatgtgtttg ctttagaggg
    14281 cagcttgagc gttgtgtttt gggtaggcat ggcagtgctt actgtgttct tgcttgtcgt
    14341 tgacttgctt gccaacatgg cgttcgtcaa gcggacaggc ggttctaaat ggggggaacg
    14401 ggcagcgttg gtcggcgtta ttgttggtgc atttgttgtt ccgccgttcg gtttgatcat
    14461 cgtcccgttt gtgcttgttc tcatagccga actcttgcaa aagcagccgt ttgaaaaggc
    14521 agtacgaatc gcatttgcct cttttctcgc ttttataagc ggcacgcttg ctaaagcggt
    14581 tgtccaaatt gtaatgattg cctggttttt gattgaagta ctctagcagc tgggccaaaa
    14641 gaaagagtgg caaccacctt gtatggtggt tgccacagag cgtagacaaa acgcctttga
    14701 g
//
