LOCUS       c00004_gnlPro..        14239 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHPCPCJM_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 21:58:02
            Original ID  :: gnl|Prokka|MHPCPCJM_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14239
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14239
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1912:4239]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1913..4239
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14239
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14239
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(2..163)
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MAKQNKAFKFRLLPNKEQSALLAKTFGCVRFVYNKMLAERKETYE
                     KFKDDKELL"
     CDS             537..1343
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="LHQFFLEKTWQLTEDWYASLDKSTVQGVYASTDPEVVAKLKEQNH
                     EFHVQFCEVFLKDEDTFLHHFEKWVMNVAQDEEHLSTPNHFIFREFFHTQEQYLDLFDS
                     FVAAHEGKYTYEELNFWRRAIIRTFEHVMLWFMKENHHYSLKRLESQQEMIKELSSPVI
                     MVGKNTALLPLVGEIDSNRAKIILEKTLEQCAEKSVLLLYIDLSGVVVIDTMVAQQIFR
                     LIETLRLIGVKCILSGIRPEVAQTAIQLGIDFNDLTIHSKLELIPE"
     CDS             1913..3112
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.2e-44, bitscore:
                     144.4, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 6.5e-40,
                     bitscore: 128.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKALIIGAGGVASVAAHKCVQNSEVFEEICIASRTKSKCDALKA
                     KLDGGKTKVTTAQVDANHVDELVALIEKVKPDVVMNLALPYQDLTIMEACLQTKTNYLD
                     TANYEPEDTAKFEYKWQWAYRERFEEAGITALLGSGFDPGVTGVFSAYALKHHFDEINY
                     IDILDCNAGDHGYPFATNFNPEINIREVSANGSYWENGKWIETKPMEIKRVYDFPEIGE
                     RDMYLLHHEELESLAANIPGIKRIRFFMTFGESYLTHLKCLENVGMTSIEPIEFEGKQI
                     VPLQFLKAVLPDPASLGPRTKGKTNIGCIFRGKKDGKDKTYYLYNVCDHEACYKEVGSQ
                     AVSYTTGVPAMIGAMMLIQGKWDRKGVYNVEEFDPDPFMEALNKWGLPWKESYNPELVD
                     "
     CDS             3112..4239
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.8e-14,
                     bitscore: 45.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFEELPTPCYVVDEQKLEDNLKILNGVMKRTGCKIVLAQKAFSM
                     FALYPLIGKYLSGTTASGLYEARLGHEEMGKENHIFSAAYREDEIDEIVSICDHVIFNS
                     FSQLEKFKGRVLAGGKKAGLRINPKCSTQTGHAIYDPCSPGSRFGVTQEQFRPNLLDGV
                     TGLHFHTLCQQNADDLETTLNAVEEKFGEWLPQMEWINFGGGHHITREGYDIPLLEKCI
                     KRMQDKYGLEVYLEPGEAVALNAGYLVTTVLDTVKNGMDIAILDTSASCHMPDVLEMPY
                     RPPLIGAGEPGEKPYTYRLGGQTCLAGDTIGDYSFDKPLKEGVRLVFGDMAIYTMVKNT
                     TFNGMPLPAIAIQYKNGDCAIVREFGYHDFKMRLG"
     CDS             4967..6043
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKKRAIVYCENQFGTTDGKTANGLIREPGNYIITAVIDSSKHGQD
                     AGMLLDNKWSGIPVCKDLEDALIHSGPKPDNFIFGIAPANAFLKPEERKVILQAMEAGL
                     NIINPLQEFLTDDEEMVAHAKACGVTIRDIRKPRPKKEWTLFTGEILKMNTPVVAVLGT
                     DGACGKRTTAKCIEKAFMEKGYRPAFIATGQTGLIQGAKYGFAMDAFPLQYLIGELERE
                     ILRANKQEHPDIIIVEGQGALSHPAYASSTGILKGARPQAVILQHAPKRKYLSDFPFAE
                     VPKVEDEISLIEHFGKTKVIGITLNHDGMADSELEDTIRRYEETYHLPVTDVLKTGTDK
                     IINALIDFFPSLKKAVVS"
     CDS             6043..7203
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="Ala_racemase_N (E-value: 2.5e-30,
                     bitscore: 97.7, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLPRVEINLEKIRHNAKTLKQLFGRKGISITGVVKGVAADLKI
                     AGTLVDAGIKSLADSKIANIEKMRKAGIKADLILLRAPGISEAEKTVRFADISMNTELD
                     TIRALSAEAMRQQKTHKIILMVEMGDLREGILLKDAPAVIREILTCPGIELVGIGTNFA
                     CFGGVLPTEQKMQAFSRFVHAMQELFSLKLPYVSGGNSANYNWAVKTKDAGAVNNVRLG
                     ESILLGRETSGGHTIPSLYQDAFCFVAEVIESKIKPSVPYGTIGKNAFGEQVTFIDRGN
                     RRRTIVSAGRHDVLVSGLTPVRPFHIIGSSSDHIILDTQNAVLVPGDEVRFYMDYGAML
                     RAMTSPYVYKTYVHGAATTKPYKQQFLLSRGTKQSRPAETEKSPAN"
     CDS             complement(7240..8082)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MKKHRLFGLVSAFLLILSLELAGCGKSSGNSSSSNPSSVSAIKKN
                     GTIKIAVFGDLPPYGWVDKNGQRQGYDVALAKQVAKDLGVKVKFVQVNANSRVDALKSN
                     KVDLVLANFTVTPERKQVVDFAKPYMKVSIGVVSPKKKPVTSVSQLKGKSLIVNKGTTA
                     ENYFTSKQKDVKLQKYDSKTEQFNALKNGRAVALADDNSYLYAWVKNHPDYTVGIKTLG
                     PNQYIAPAVKKGNQSLLNWMNKEITKLNNNGFFKSDYNKNLAPYFGSDIRAEDIIITK"
     CDS             complement(8110..8847)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MAEPLLKVEHLKKSYGEKQVLEDISFEVEEGSVVVLLGPSGSGKS
                     TLIRCLNGLEAFQGGTILFNGETVRPSPKNWRRLRQQIGMVFQSYDLFPNMTVLENILL
                     GAVKVQKRKKDEAARQAMGLLKEVGMEQYANAYPRQLSGGQKQRVAIVRALELNPKLML
                     FDEVTASLDPEMVRGVLEIILRLAREKMTMIVVTHEMNFARKIGDKILFLEDGKILEET
                     PGHQFFTKPQTERAKNFLESMDF"
     CDS             complement(8840..9529)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 64.8; E-value: 2.8e-20)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_9"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.8e-20, bitscore:
                     64.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGHLGINIFFEGANFLRLLGGLYVSAKIAFLSIVFGGILGIVLGV
                     LRTLHNPLLRLLLRLYLEFFRIVPTIVLLFLFYYILPQSFNINYKADTVGTIVFSLWMA
                     AEMSDIVRGALISVPRHQVESGKAVGLSTVQLYRYVLLPQSVHLMIPATINLMTRIIKT
                     TSLLLLISVVDVINVGQQIIEANSHRYQDGAFWIYGFIFILYFILCYPLSRLARRLERR
                     GKAGANG"
     CDS             complement(9510..10169)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 61.7; E-value: 2.5e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_10"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.5e-19, bitscore:
                     61.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWTVVQNSLPMFEKGFWLTLRLSFFGIIGAGVLGLICSFIQYFK
                     VPVLRKLVSAYVELSRNTPLLIQLFFLFYGLPQVGIKFSAEVCGIIGIIFLGGSYMAEG
                     FSGGLAGVSKTQIESGLAIGLSRFQLARYVIFPQGLMLSVPAFAANVIFLIKETSIFTV
                     LAIPELTNTALDLIGMYYNTNEYLFMLVVAYAIILIPLSILLTWLEKKVRYGTFGN"
     CDS             complement(10675..12177)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_11"
                     /sec_met_domain="DAO (E-value: 1.6e-10, bitscore: 33.0,
                     seeds: 522, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRQGKTDVILIGAGIMSATLGTLLKELTPDWEITVYEKLAKPG
                     EESSNEWNNAGTGHSALCELNYTPEKPDGSIDITKAVNVNEQFQLSRQFWSYLVSKGLI
                     RNPQDFIRPIPHMSFVEGEENVAFLKKRFKALSAHPLFEGMAFSDDPGQLKEWIPLVME
                     GRKSNEPVAATKSDAGTDVNFGALTRMLFDHLQRQNVEINYKHAVQDIKRTPEGNWEVK
                     VHDIEHNRIEYHTAKFIFIGAGGGSLPLLQKTGIPESKHIGGFPVSGLFMVCNNPEVIS
                     RHHAKVYGKAKVGAPPMSVPHLDTRYIDHKKCLLFGPFAGFSPKFLKTGSNLDLIGSVK
                     PNNVVTMLASGAKNVPLVKYLIGQLLLSDEKRLETLQEFIPDARLEDWDVVVAGQRVQV
                     IKDTEAGGKGTLQFGTEVVTAADGSVAALLGASPGASTAVHVMLEVIEKCFPDRKKAWA
                     PKIKEMIPSYGVRLAENPDLLHQIHAETAETLGLTEKEPAYR"
     CDS             12526..13857
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sugar_tr"
                     /gene_functions="transport (smcogs) SMCOG1007:sugar and
                     other transporter (Score: 91; E-value: 2.5e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_12"
                     /sec_met_domain="Sugar_tr (E-value: 2.5e-28, bitscore:
                     91.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LAQTTGRTSRHVTANIFKGSLGNLIEWYDWYVYSAFAVYFSSEFF
                     PEGNQTVQLLNTAGIFAIGFLMRPLGSLIMGRYADRYGRRAALTLSVAIMALGSLVIAC
                     TPGYSRIGVLSPVILVLARLVQGISLGGEYGTSATYLSEMASSGRRGFYSSFQYVTLVS
                     GQLIALGVQIVLQLALNESEMTSWGWRIPFVIGAIGALVVLWLRRTMDESEQFEEMGSE
                     TRKNAGTLKVLLNYPKAVLTVVGVTLGGTVAFYTFTTYLQKFMVNTSGIDKETVSWINF
                     IALFIFVVFQPLAGKLSDRIGRRPLLIGFGILGTLLTVPIFLWLRETQNPVFAFLLMMA
                     GLIIVTGYTSINAIVKAELFPTEIRALGVGFPYSLTVAIFGGTAEFIALGLKNAGVESA
                     FFYYVAGCIAISLVTYLFMAESSKHSRIEAELQSRPDSKNKIIT"
     CDS             complement(14026..14202)
                     /locus_tag="ctg4_13"
                     /transl_table=11
                     /translation="MIVWLFRAGKQGEFENKFLEDGRVYLTWDDLNINLKEITSKEDLY
                     KRLIEHYDLKRWP"
ORIGIN
        1 taagcaattc tttatcatcc ttgaactttt catacgtttc tttgcgttca gctaacatct
       61 tattgtagac aaagcgaaca caaccaaatg tcttagctaa taatgcggat tgttctttgt
      121 ttggtaacaa acgaaacttg aaagctttgt tttgcttggc catatcaatt cacctcactt
      181 tgtgcggaaa aatttcgtat atattgatta tatcgtaaaa aatccgtaca atcaatatga
      241 ggtgataatc atgagagaag agaaagaacg tgtagaaatt cgtatgccta agacgatatt
      301 agagaaattg gagcaatatc aaaaagaaaa tgggattcca actagaacag ccgcaatctt
      361 agaattgttg agaaaaggat tggaaaaata actttggcta aagccaaccg aaattcatct
      421 cccacctact cattggtgcg attcgcacct tcacattcct tgaggatggg agacttcttt
      481 cggaaaaccg ttaaatctta catcatgcgg gtgataaaat ggagctaaga caggcattgc
      541 atcaattttt ccttgaaaaa acatggcaat tgacggaaga ctggtacgca tcgctcgaca
      601 aaagcaccgt gcagggggtt tatgcgtcca ccgaccccga agtggttgca aaactgaaag
      661 agcaaaacca cgagttccac gtccagtttt gtgaagtgtt tttaaaagat gaagatacat
      721 ttttacacca ttttgaaaag tgggtaatga acgttgcaca ggatgaagag catctttcca
      781 caccgaacca ctttattttt cgcgagttct tccacacgca ggaacaatat ctcgatctgt
      841 ttgattcatt tgttgcagcc cacgagggaa aatatacata cgaggaattg aatttttgga
      901 gaagggcgat catccggaca ttcgaacatg tcatgctctg gtttatgaaa gaaaaccacc
      961 attattcctt aaagcggttg gagtcccagc aggaaatgat taaagagctg agttcccccg
     1021 tcattatggt cggcaaaaat accgcgctgc tgccgcttgt cggggaaatt gattccaacc
     1081 gtgcgaaaat tattctggaa aaaacactcg aacaatgcgc agaaaaaagc gttctccttc
     1141 tgtacattga tttatccggc gtggtcgtca tcgatacgat ggtcgcccag caaattttcc
     1201 ggctgattga gacgctgcgg ttaatcgggg taaaatgcat tctttccggc atccgtccgg
     1261 aggtggcgca aactgccatt caattgggca ttgattttaa tgacttaacg atccactcaa
     1321 aactggaact cataccggaa tgatggcgtt ttttcagcca tccgggcata ccgttttgga
     1381 aaatagagat ccggggagga gccccccttt gaaacgcagc cgtcccgata tggtttaaga
     1441 aaatttttct tcttgctatt ttaagtccgt gctgatacga tagaagagca tgatttggaa
     1501 ggcatatatt cagcatcagg agtctttcca agcagataat tttggccagt ggagtaaagg
     1561 catcggtgtg ccgggccaaa tgccgaatcg gcaacttttg gttgccttat tgattgagtg
     1621 ggaaactcaa attttataag ttggttactt tacaaccggt gcttgtgcac atcaacttgt
     1681 gaaacgatca ataagagtgg taaaagtaat tatttgctat atagactctg atcctataag
     1741 aatataaagc tttcttccat attgtccacg gacttttatg gcaggcgtat atctgtttat
     1801 gcggatatgc atgctttttt aggatgatga tttcaagcaa gtgttgtgcg cacgtatgcg
     1861 gattgcactt gctttttatt atgcaaaaat tctatttgaa ggagacagaa gaatgggaaa
     1921 agcgttgatt atcggggccg gcggcgtggc atcggtcgct gcgcataaat gtgtccaaaa
     1981 cagcgaagtc tttgaagaaa tctgcatcgc aagccgcacg aaatcaaaat gcgatgcgtt
     2041 aaaagcaaag cttgacggcg gaaaaacgaa agtgacgact gcacaggtcg atgccaatca
     2101 cgtcgatgaa ctggttgctt taattgaaaa agtgaaaccg gatgtcgtca tgaatctggc
     2161 gctgccttac caggatttaa ccatcatgga agcctgcctt caaacaaaaa caaactatct
     2221 cgacaccgcg aactatgagc cggaagacac ggcaaaattt gaatacaaat ggcaatgggc
     2281 ataccgcgaa cgttttgaag aagccggcat taccgccctt ctcggcagcg gctttgaccc
     2341 gggcgtaaca ggcgtatttt ccgcttatgc cctgaaacac cattttgatg aaatcaatta
     2401 tattgatatt ttggactgca atgccggcga ccatggctat ccgttcgcaa caaacttcaa
     2461 cccggaaatc aacatccgcg aagtttccgc caacggcagc tactgggaaa acggcaaatg
     2521 gattgaaaca aaaccgatgg agatcaaacg cgtgtatgat tttcctgaaa tcggcgaacg
     2581 cgacatgtac ctgctgcacc atgaagagct ggagtcgctt gccgcaaata tccctggcat
     2641 taaacggatc cgtttcttca tgacgtttgg cgaaagttac ctgacacatt tgaaatgcct
     2701 ggaaaacgtc ggcatgactt caattgagcc gattgaattt gaaggcaaac aaatcgtgcc
     2761 gctgcaattt ctgaaagctg tgctgccgga tccggcttcc ctcggcccgc gcacaaaagg
     2821 gaaaacgaat atcggctgca ttttccgcgg caaaaaagac ggcaaggaca aaacctatta
     2881 cctttacaat gtatgcgacc atgaagcctg ctacaaagaa gtcggctcgc aggcggtatc
     2941 gtacacaacc ggcgtgccgg cgatgatcgg cgcgatgatg ctgatccagg gcaaatggga
     3001 cagaaaaggc gtttataatg tggaagagtt cgatcctgat ccgttcatgg aagctctgaa
     3061 caaatggggc ctgccgtgga aagaaagcta taatccggag cttgtcgact gatgcgattt
     3121 gaagaactgc cgacgccttg ctatgtagtt gatgaacaaa agctcgaaga caatttgaaa
     3181 attttaaacg gcgtgatgaa acggaccggg tgtaaaattg ttttggcgca aaaagctttt
     3241 tcgatgtttg ctttgtaccc gctcatcggc aaatacttga gcgggacaac agcaagcggc
     3301 ttgtatgaag cgcgcctcgg gcatgaggaa atgggaaaag aaaaccatat tttttccgcc
     3361 gcttaccgtg aagatgaaat cgatgagatc gtctcgattt gcgatcatgt tatttttaat
     3421 tcattttcac agcttgagaa attcaaaggc cgcgtgcttg caggcgggaa aaaggcgggc
     3481 ctgcgcatca atccgaaatg ctcgacacag accgggcatg caatttatga cccttgttcg
     3541 ccgggctcgc gcttcggtgt gacgcaggaa cagttccgcc ctaatcttct ggacggcgta
     3601 accggcctcc atttccacac gctctgccag caaaatgcgg acgatctgga gacaacgctg
     3661 aatgccgttg aagaaaagtt cggggaatgg ctgccgcaaa tggaatggat caatttcggc
     3721 ggcggccacc atattacgag ggaaggctat gacattccct tgctcgaaaa atgcatcaag
     3781 cggatgcagg acaagtacgg tttggaagtc taccttgagc cgggcgaagc tgttgcttta
     3841 aatgccggct atcttgtcac gacagtgctt gacacagtga aaaacggcat ggacatcgcg
     3901 atcctcgata cgtccgcctc gtgccatatg ccggatgtgc tggaaatgcc gtaccgcccg
     3961 ccgctcatcg gggccgggga gccgggcgaa aaaccgtata cgtaccggct tggcggccaa
     4021 acatgcctcg ccggcgatac gatcggcgat tattccttcg ataagccgct taaagaaggc
     4081 gttcgccttg tatttggcga tatggccatc tacaccatgg tgaaaaatac cacctttaat
     4141 ggcatgccgc ttccggctat cgcgatccaa tataaaaacg gcgactgcgc aattgtccgt
     4201 gaattcggct atcacgactt taaaatgaga ctcgggtgaa tacctgcatt acccgggcta
     4261 agtggaaaca atatagacga gggagaaaag cgaaaccgcc ggcagcctat ccgtggctga
     4321 tgatgctttc tgctgcagat taccggaaaa agacggttga cacggacatt ttgcaggaac
     4381 tggaggaatg ggcgatgaat gggtaggaag tgcttgacgc aatcaaagag tgggagaatt
     4441 tgagtgccaa tcgggaaaac aaagtattgt acgaagcccg gctgaaattt tacgcgacca
     4501 gctcgcgaat atccgcggtg aaagagagga aggcctcaga gaagggattc aaaaagggat
     4561 tgaagaaggg gtacaaatag caatcaaaaa atgctgcgca aaggcacccc acccgaaacg
     4621 atcgcagata tgcttgatta tccgcttgaa gaaatcaaaa aacccagcgg gaattagagc
     4681 ggggtagcta actgaatcgc gcgcccgccg cttccaaacg caagggggct tttccaatgc
     4741 cggactggcg gcggaatggc ccccttttct atcttggttg catgcttccg gcttcccttt
     4801 tttccacaac attgttataa taatatttgg aagcttccaa taacctgggg tttccggcat
     4861 gcccatacgt aaacccggac agctatcttc tttagtattt ttactatttg aagccattag
     4921 gtgttctttt tgtgttgcct aaatttcaat aaatggaggg atggcaatga aaaagcgggc
     4981 aattgtgtat tgcgaaaacc aatttggcac aacagatggc aaaacagcaa acgggctcat
     5041 ccgtgaaccc gggaattaca tcattactgc cgtcattgac agcagcaaac acgggcagga
     5101 tgccggcatg ctcctcgaca acaaatggag cggcattccg gtttgcaaag acctggaaga
     5161 cgcgctcatc cactccggcc cgaaaccgga taacttcatt ttcggcatcg cgccggcgaa
     5221 cgccttttta aagccggaag aaagaaaagt catcctgcag gcaatggaag ccggattgaa
     5281 catcattaac ccgctccagg aattcttaac cgatgatgaa gaaatggtgg cccatgcaaa
     5341 ggcttgcggt gtcacgatcc gcgatatccg taaaccgcgg ccgaaaaaag aatggacttt
     5401 gtttaccgga gaaattttga aaatgaacac ccctgtcgtt gccgtgctcg ggacagacgg
     5461 ggcctgcgga aaacggacaa ccgccaaatg cattgaaaag gcattcatgg aaaaaggcta
     5521 ccgcccggca tttatcgcaa ccgggcagac aggtttgatc cagggcgcca agtacgggtt
     5581 tgcgatggat gctttcccgc tccaatattt aatcggcgaa ctggaacgcg aaattttgcg
     5641 ggccaataaa caagaacacc cggatattat catcgtggaa ggccagggcg cgctcagcca
     5701 cccggcatat gcaagctcaa ccggcatttt aaaaggagca aggccgcaag cagtcatttt
     5761 acagcacgcc ccgaaacgaa aatatttatc cgattttcca tttgccgaag tgccgaaagt
     5821 ggaagatgaa atcagcctga ttgaacattt cggaaagaca aaagtcatcg gcattacgct
     5881 caaccatgat ggaatggcag acagcgaact ggaagacacc atccgccgct atgaagaaac
     5941 ttaccatctt ccggttacgg atgttttaaa aaccggcaca gacaaaatca taaacgccct
     6001 gatcgatttc ttcccttccc tgaaaaaggc agtggtttcc tgatggccgt tctgccacgg
     6061 gtggaaatca atctggagaa gatccggcat aatgcgaaaa cattaaaaca attattcggg
     6121 aggaaaggaa tcagcattac aggcgttgtg aaaggtgtcg cagccgattt aaaaattgcc
     6181 ggcaccctgg tggatgcagg catcaaaagc ctcgcagact cgaagattgc aaatatcgaa
     6241 aaaatgagaa aagcgggaat caaggcggat ttgattttgc tccgtgcccc cgggatcagc
     6301 gaagcggaaa aaacggtccg gtttgcggat atcagcatga acacggagct ggatacgatc
     6361 cgcgcattat ccgctgaagc gatgcggcaa cagaaaaccc ataaaatcat cctgatggtg
     6421 gaaatgggag atttgaggga aggcatatta ttaaaagatg cccctgctgt gatcagagaa
     6481 atattaacct gccccgggat tgaactggtc ggaatcggga caaattttgc ctgctttgga
     6541 ggtgtgctcc cgaccgaaca gaagatgcag gcgttttccc ggtttgtcca tgccatgcag
     6601 gagctgtttt ccctcaaact tccttatgtt tccggcggca actccgccaa ctacaactgg
     6661 gccgtaaaaa caaaagacgc cggggccgta aacaatgtgc ggctcggcga gtccattttg
     6721 ctgggccgcg aaacatcagg cgggcatacc attccgtctt tatatcagga tgccttttgc
     6781 tttgttgccg aagtcatcga atcaaaaatc aaaccttccg tgccgtatgg gacaatcggc
     6841 aaaaatgcat tcggggaaca ggtcaccttt atcgacaggg gcaacagaag gcggacgatt
     6901 gtcagtgcag ggcggcatga tgtgcttgtt tcaggcctta cccctgtccg gccgttccat
     6961 atcattggct caagcagcga ccatatcatt ttggatacac aaaatgcggt tctcgtgccg
     7021 ggcgatgagg tgagatttta tatggactac ggcgcgatgc tgagagccat gacgtctccg
     7081 tatgtttata aaacgtacgt ccatggtgcg gccacaacca agccttacaa acaacagttt
     7141 ctgctttcgc gcggaacaaa gcaaagccgg cccgcggaaa ccgaaaaaag ccccgccaat
     7201 taaagaaaag caggctgcaa aaacggcagc ctgccttttt tacttcgtta taatgatgtc
     7261 ttccgcacgg atatcactgc caaaatatgg cgccagattt ttgttgtaat cacttttgaa
     7321 aaagccattg ttgtttaact tcgtaatttc tttgttcatc caattgagga gcgattgatt
     7381 cccttttttc acagcagggg caatatattg gttcggcccg agcgttttaa tgccaaccgt
     7441 ataatccgga tggtttttca cccaggcata caggtaggaa ttgtcgtccg ccagtgcaac
     7501 ggcccgcccg tttttaagcg cattgaactg ttctgttttg gaatcgtact tttgcaattt
     7561 cacatctttt tgtttgcttg taaaatagtt ttccgcagtg gtgcccttgt tgacgatcaa
     7621 agacttgcct tttaattggc tgacacttgt gaccggcttt ttcttcggtg aaacaacacc
     7681 gatggaaact ttcatgtacg gcttggcaaa atcaacaact tgcttccgtt ccggtgtgac
     7741 tgtaaaattc gccagaacca gatccacttt atttgatttc aatgcatcca cacggctgtt
     7801 ggcattcact tgcacgaatt tcacttttac gccaagatct ttggcaactt gtttggcgag
     7861 cgcaacatca tatccctggc gttgcccgtt tttatcgacc catccgtatg gcggaagatc
     7921 gccgaatacg gcaattttga tcgtgccgtt tttcttaatg gctgaaacac tggacggatt
     7981 gctgcttgaa gaattgccgg aacttttgcc gcagcctgca agctccagcg acaaaattaa
     8041 taaaaatgct gaaaccaaac caaacaaacg atgctttttc atggtctaac cctccaaaat
     8101 atttttcttt taaaaatcca tgctttccag aaaatttttc gcccgctctg tctgcggttt
     8161 tgtgaaaaat tggtgcccgg gggtttcttc gagaatcttc ccgtcttcca aaaacaagat
     8221 tttatccccg attttccggg caaaattcat ttcatgcgtg acgacaatca tcgtcatctt
     8281 ttctcttgcc aaccgcagga tgatctcgag cacgccgcgc accatttccg ggtcaagcga
     8341 ggcggtcact tcatcaaaca gcatcagctt cgggttcagc tcaagcgcgc ggacaatcgc
     8401 cacccgctgt ttctgcccgc cggaaagctg gcgcggatag gcattggcat actgctccat
     8461 gccgacttcc tttaacaggc ccattgcctg gcgcgccgct tcgtcttttt tccgtttctg
     8521 gactttcact gcaccgagca ggatgttttc caacaccgtc atattcggaa acagatcata
     8581 gctctggaaa accattccga tctgctgcct gagcctgcgc caatttttcg gcgacggccg
     8641 cacggtttcc ccattaaaca gaatggtgcc accctggaag gcttcgagac cgtttaagca
     8701 gcggatcaat gtactttttc ccgatcccga cggcccgagg agaacaacaa cactgccttc
     8761 ctccacttcg aaagagatat cctccagcac ttgtttttca ccgtacgatt tttttaaatg
     8821 ttcgactttc agtaaaggtt cagccattag cccctgcttt gcccctcctt tctaaccgcc
     8881 ttgccagccg ggaaagcgga tagcataaaa tgaaatacag gataaatata aaaccgtata
     8941 tccaaaacgc gccatcctga tagcggtggc tattcgcttc gatgatttgc tggccgacat
     9001 tgatgacatc cactacgctg atcaatagca aaagagaagt cgtcttaatt attctggtca
     9061 tcaggttaat ggtcgccgga atcattaagt ggaccgattg cggcagcagc acgtaccggt
     9121 aaagctgaac cgtgcttaaa ccgaccgctt ttccggattc cacctgatgc cttgggacag
     9181 aaatcagcgc accacggaca atatcgctca tttcagcagc catccacagg ctgaagacaa
     9241 tcgtcccgac cgtatccgcc ttatagttga tgttaaagct ttgcggcaga atatagtaaa
     9301 acaaaaataa caggacaatc gtcggcacga tgcggaaaaa ctccaaatac agcctgagta
     9361 aaaggcggag caacggattg tgcaatgtcc ttaaaacccc cagcacgatg ccgaggatac
     9421 cgccgaaaac gatggacaga aaagcaattt ttgccgatac gtataatcca cccagtaaac
     9481 gtaaaaagtt ggctccttca aaaaagatat taattcccaa atgtcccata acgcaccttc
     9541 ttctccagcc atgtcagcaa gatggacaat ggaattaaaa tgatggcata agccacaacg
     9601 agcataaaca gatactcatt cgtgttgtaa tacatcccga tcaagtcaag tgccgtgttg
     9661 gtcagttccg gaatcgccaa cacggtaaag atagaggttt ccttgattaa aaaaatgaca
     9721 tttgcggcga atgccgggac actgagcatc aatccctgcg gaaagatgac gtagcgtgcc
     9781 agctggaacc tgctcagacc gatcgcaagc ccggactcaa tctgcgtttt cgaaacgcct
     9841 gcaagccctc cggaaaaccc ttctgccata taactgccgc caagaaaaat aatcccgata
     9901 atcccgcaaa cctcggcaga aaatttgatc ccgacttgcg gaagcccgta aaaaaggaaa
     9961 aataactgga tcaataaagg cgtattgcgg gacagttcca cataggccga tacaagcttc
    10021 cgtaaaaccg gcaccttaaa atactggata aaactgcata tcaagccaag aacaccagcc
    10081 ccgataatgc cgaaaaagga aagccgcaaa gtgagccaga atcctttttc aaacatgggc
    10141 aagctgtttt gcacaacggt ccagtccatc tcacccctcc tattttggaa aattctcttc
    10201 aatccaggcg ggcttgcgcc agccgtccgg tatgtatggc gttgctgtcc cgaatcaggt
    10261 gcttgcgcgt ttaaaggccg gacgacaaaa agccgtttcc taagaaaacg actgcctttt
    10321 ttcaggtatt gctgcagttt tcttatcttg atagacgatc atgaactgta ctattatgat
    10381 gccggtttcc aaggacagcc cttccgccgc ccgggataag aaattttcag cattttagca
    10441 acatctttat tttactgaac gccgggacaa aaatcaatat attcctatcg acttgatagg
    10501 gttttctttg catagcaccc aaaaaaaaca gcatgccaaa gttgttcctc cgcttgcacc
    10561 cgtactgctt tccggctgcc tgcaaaatga atgccggtta agacgcgtta cagccaaaaa
    10621 aaggccttca atccgcttta ggatcaaagg cccttcattt tagcgctcca cgcgttaccg
    10681 gtaggccggt tctttttccg tcaggccgag cgtctctgcc gtttcagcgt ggatttgatg
    10741 cagcagatcc gggttttctg cgagccgcac gccataagaa ggaatcattt cttttatttt
    10801 tggtgcccat gcttttttcc ggtccgggaa gcatttttca atgacttcga gcataacatg
    10861 gacagcagta gaagcacccg gcgaagcgcc gagcaatgcc gcgactgaac cgtcagcagc
    10921 tgttaccacc tctgtaccga actggagcgt gccttttccg cctgcttccg tatctttaat
    10981 cacctggaca cgctgcccgg ctacgacaac atcccagtct tccaatctcg catccggaat
    11041 gaattcctgc agtgtctcca ggcgtttttc gtctgacaat agaagctgcc cgatcaaata
    11101 tttaacaagc ggtacatttt ttgccccgga cgcaagcatc gttacgacat tattcggctt
    11161 cacagaacca atcaggtcta aatttgaccc tgtttttaaa aacttcggcg agaagccggc
    11221 aaacgggccg aacagcaaac actttttatg gtcaatatat cttgtatcca aatgcggcac
    11281 ggacatcggc ggcgcgccga ctttcgcttt gccgtacact tttgcatggt ggcggctaat
    11341 gacttcagga ttgttgcaca ccataaataa cccgcttacc ggaaaccctc caatatgttt
    11401 ggactccgga atgccggttt tttggagcaa cggcaagctt ccgccaccgg caccgataaa
    11461 aataaatttc gccgtatggt attcgatcct gttgtgctca atatcatgca ctttcacttc
    11521 ccagtttcct tccggggtgc gtttaatatc ctgaacggca tgcttgtagt tgatttcgac
    11581 attttggcgt tgcaaatgat caaacagcat gcgggtcaag gcgccaaagt tgacgtccgt
    11641 ccctgcatcg ctttttgtcg ccgcaaccgg ttcattggac ttcctgcctt ccatcacaag
    11701 cggaatccat tcctttaatt gcccgggatc gtcggaaaac gccattcctt caaaaagcgg
    11761 atgggctgac agcgctttaa atcgcttttt tagaaaagca acgttctcct ccccttctac
    11821 aaagctcata tgcgggatcg gccggataaa gtcctgcgga ttgcggatca gccccttgct
    11881 gaccaggtag gaccagaact gccttgaaag ctggaattgt tcatttacat ttacagcttt
    11941 tgtaatgtct attgagccgt ccggtttttc aggcgtataa ttcagctcac ataatgccga
    12001 gtgcccggtc cccgcattgt tccattcatt cgaactttct tcccctggtt ttgccagctt
    12061 ctcatatacg gtgatttccc aatccggagt cagttctttc agcaaggtgc ccagcgttgc
    12121 gctcataatg ccggcaccaa ttaagatgac gtctgtcttt ccctgtctga tgctcatgat
    12181 taccttctcc ttatccctat atttgctaat attattccgg acacactgcc tctttttcag
    12241 aacaaggcag tccccgggaa aacgttttcc aagtcttaat atcataatat catattttat
    12301 gataattctt tagaataatg atacacaatt taacaatgga aatatcagga aaccttttta
    12361 tttgctgaat gattcattct tcatttttct taaaaatata atataatgaa tcttgtaaat
    12421 agaaatttta ctggtatatt tcttgcattt tccaaagggg gatgccagga gatatttttc
    12481 acggattgaa gacggaattt tcattttaca aagggggaag acaaattggc acaaacaacc
    12541 ggacgcacat ccagacatgt gactgctaac atctttaaag gatcacttgg caatctgatc
    12601 gaatggtatg attggtatgt ttattctgcg tttgcggttt atttttcatc agagtttttt
    12661 ccggagggga accaaactgt ccagttattg aatacagccg ggatttttgc cattggtttt
    12721 ctgatgcggc cgctcgggag cctgatcatg ggccggtatg cagaccggta cggccgccgg
    12781 gctgcactga ccctttccgt tgccattatg gcgctcggtt cgcttgtcat tgcctgtaca
    12841 ccgggataca gcaggattgg tgtgctgtca ccggttattt tggtcctggc ccggcttgtg
    12901 caggggatct cgctgggcgg ggaatacggc acttctgcta cctatttgtc cgaaatggca
    12961 agcagcggcc gccgcggctt ctattccagt ttccaatatg tcacgcttgt atcggggcag
    13021 ttgatcgcac ttggtgtcca aattgtgctc caactcgcat taaatgaaag cgaaatgacc
    13081 tcgtggggat ggcggatccc gtttgtgatc ggcgcgattg gcgcattggt ggtcttgtgg
    13141 ctgcgccgta cgatggacga gtccgaacaa ttcgaggaga tgggatcgga aacgcggaaa
    13201 aatgccggaa cgctgaaggt cctattgaat tatccgaaag cggtgctgac cgttgtcggc
    13261 gttacacttg gcggcactgt cgcattctac acattcacca cctatctgca aaaatttatg
    13321 gtgaacacgt ccggaattga taaagaaacc gtcagctgga tcaactttat tgcccttttc
    13381 atctttgttg ttttccagcc gcttgccgga aagctgtccg accggatcgg gcgcaggccg
    13441 ctgttaatcg gcttcggcat tctcgggacc cttttgaccg taccgatatt tttatggttg
    13501 agagaaacgc agaacccggt ttttgctttt cttctcatga tggcagggct gatcattgta
    13561 accggctata cttccatcaa tgccattgtg aaagctgagc tgttcccgac tgaaatccgc
    13621 gcgcttggtg tcgggtttcc ttactcatta actgtcgcaa tctttggcgg aacagccgag
    13681 tttatcgcgc ttgggctgaa aaatgccggc gtggaatccg cctttttcta ctacgtcgcc
    13741 ggctgtattg ccatcagcct ggtcacttat ttattcatgg ccgaatcctc gaagcattcc
    13801 cggatcgaag cagaacttca atcccgcccg gattcgaaaa acaaaattat cacctgaaaa
    13861 agccaaacag ctgcagcgtg gcaggctgca gctgttttat ttttccttgc aagatgaaag
    13921 accggtaata tccaaaaacc agcccgtaac ttcaatcgtg aatacgatac gggccctcct
    13981 gaatgaagga tgatatttgg accgcgcttg cctggtgcac cggcattatg gccatcgctt
    14041 taaatcatag tgttcgatta gtcgtttata taaatcctct ttggaagtaa tctcttttag
    14101 attaatattt aaatcatccc aagtaagata tacccttcca tcttctaaaa atttgttttc
    14161 gaactcccct tgttttcctg cacgaaataa ccaaacaatc attatgtaac tcctttcttt
    14221 gacgtagcat aataatttt
//
