LOCUS       c00044_gnlPro..        14017 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIMOLNBN_45.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 20:43:05
            Original ID  :: gnl|Prokka|DIMOLNBN_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14017
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14017
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1690:4017]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1691..4017
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14017
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14017
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             3..170
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="PYNQYEVIIMREEKERVEIRMPKTILEKLEQYQKENGIPTRTAAI
                     LELLRKGLEK"
     CDS             712..1122
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="MLWFMKENHHYSLKRLESQQEMIKELSSPVIMVGKNTALLPLVGE
                     IDSNRAKIILEKTLEQCAEKSVLLLYIDLSGVVVIDTMVAQQIFRLIETLRLIGVKSIL
                     SGIRPEVAQTAIQLGIDFNDVTIHSKLELMSE"
     CDS             1691..2890
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_3"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.1e-44, bitscore:
                     144.4, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3.3e-40,
                     bitscore: 128.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKALIIGAGGVASVAAHKCVQNSEVFEEICIASRTKSKCDALKA
                     KLDGGKTKVTTAQVDANHVDELVALIEKVKPDVVMNLALPYQDLTIMEACLQTKTNYLD
                     TANYEPEDTAKFEYKWQWAYRERFEEAGITALLGSGFDPGVTGVFSAYALKHHFDEINY
                     IDILDCNAGDHGYPFATNFNPEINIREVSANGSYWENGKWIETKPMEIKRVYDFPEIGE
                     RDMYLLHHEELESLAANIPGIKRIRFFMTFGESYLTHLKCLENVGMTSIEPIEFEGKQI
                     VPLQFLKAVLPDPASLGPRTKGKTNIGCIFRGKKDGKDKTYYLYNVCDHEACYKEVGSQ
                     AVSYTTGVPAMIGAMMLIQGKWDRKGVYNVEEFDPDPFMEALNKWGLPWKESYNPELVD
                     "
     CDS             2890..4017
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_4"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 9.4e-15,
                     bitscore: 45.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFEELPTPCYVVDEQKLEDNLKILNGVMKRTGCKIVLAQKAFSM
                     FALYPLIGKYLSGTTASGLYEARLGHEEMGKENHIFSAAYREDEIDEIVSICDHVIFNS
                     FSQLEKFKGRVLAGGKKAGLRINPECSTQTGHAIYDPCSPGSRFGVTQEQFRPNLLDGV
                     TGLHFHTLCQQNADDLETTLNAVEEKFGEWLPQMEWINFGGGHHITREGYDIPLLEKCI
                     KRMQDKYGLEVYLEPGEAVALNAGYLVTTVLDTVKNGMDIAILDTSASCHMPDVLEMPY
                     RPPLIGAGEPGEKPYTYRLGGQTCLAGDTIGDYSFDKPLKEGVRLVFGDMAIYTMVKNT
                     TFNGMPLPAIAIQYKNGDCAIVREFGYHDFKMRLG"
     CDS             4014..4184
                     /locus_tag="ctg44_5"
                     /transl_table=11
                     /translation="VNTCITRAKWKQYRRGRKAKPPAAYPWLMMLSAADYRKKTVNTDI
                     LQELEEWAMNG"
     CDS             complement(4433..4696)
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="MASNSKNTKEDSCPGLRMGMPETPGYWKLPNIIITMLWKKGKPEA
                     CNQDSKGGHSAASPALEMPPCVWKRRARDSVSYPALIPAGFF"
     CDS             4746..5822
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="MKKRAIVYCENQFGTTDGKTANGLIREPGNYTITAVIDSSKHGQD
                     AGMLLDNKWSGIPVCKDLEDALIHSGPKPDDFIFGIAPANAFLKPEERKVILQAMEAGL
                     NIINPLQEFLTDDEEMVAHAKACGVTIRDIRKPRPKKEWTLFTGEILKMNTPVVAVLGT
                     DGACGKRTTAKCIEKAFMEKGYRPAFIATGQTGLIQGAKYGFAMDAFPLQYLIGELERE
                     ILRANKQEHPDIIIVEGQGALSHPAYASSTGILKGARPQAVILQHAPKRKYLSDFPFAE
                     VPKVEDEISLIEHFGKTKVIGITLNHDGMADSELEDTIRRYEETYHLPVTDVLKTGTDK
                     IINALIDFFPSLKKAVVS"
     CDS             5822..6982
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ala_racemase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_8"
                     /sec_met_domain="Ala_racemase_N (E-value: 1.7e-30,
                     bitscore: 97.3, seeds: 314, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLPRVEINLEKIRHNAETLKQLFGRKGISITGVVKGVAADLKI
                     AGTLVDAGIKSLADSKIANIEKMRKAGIKADLILLRAPGISEAEKTVRFADISMNTELD
                     TIRALSAEAVRQQKTHKIILMVEMGDLREGILLKDAPAVIREILTCPGIELAGIGTNFA
                     CFGGVLPTEQKMQAFSRFVHAMQELFSLKLPYVSGGNSANYNWAVKTKDAGAVNNVRLG
                     ESILLGRETSGGHTIPSLYQDAFCFVAEVIESKIKPSVPYGTIGKNAFGEQVTFIDRGN
                     RRRTIVSAGRHDVLVSGLTPVRPFHIIGSSSDHIILDTQNAVLVPGDEVRFYMDYGAML
                     RAMTSPYVYKTYVHGAATTKPYKQQFLLSRGTKQSRPAETEKSPAN"
     CDS             complement(7019..7861)
                     /locus_tag="ctg44_9"
                     /transl_table=11
                     /translation="MKKHRLFGLVSAFLLILSLALAGCGKSSGNSSSSNPSSVSAIKKN
                     GTIKIAVFGDLPPYGWVDKNGQRQGYDVALAKQVAKDLGVKVKFVQVNANSRVDALKSN
                     KVDLVLANFTVTPERKQVVDFAKPYMKVSIGVVSPKKKPVTSVSQLKGKSLIVNKGTTA
                     ENYFTSKQKDVKLQKYDSKTEQFNALKNGRAVALADDNSYLYAWVKNHPDYTVGIKTLG
                     PNQYIAPAVKKGNQSLLNWMNKEITKLNNNGFFKSDYNKNLAPYFGSDIRAEDIIITK"
     CDS             complement(7889..8626)
                     /locus_tag="ctg44_10"
                     /transl_table=11
                     /translation="MAEPLLKVEHLKKSYGEKQVLEDISFEVEEGSVVVLLGPSGSGKS
                     TLIRCLNGLEAFQGGTILFNGETVRPSPKNWRRLRQQIGMVFQSYDLFPNMTVLENILL
                     GAVKVQKRKKDEAARQAMGLLKEVGMEQYANAYPRQLSGGQKQRVAIVRALELNPKLML
                     FDEVTASLDPEMVRGVLEIILRLAREKMTMIVVTHEMNFARQIGDKILFLEDGKILEET
                     PGRQFFTKPQTERAKNFLESMDF"
     CDS             complement(8619..9185)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 61.6; E-value: 2.6e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_11"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.3e-19, bitscore:
                     61.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLGVLRTLHNPLLRLLLRLYLEFFRIVPTIVLLFLFYYILPQSFN
                     INYKADTVGTIVFSLWMAAEMSDIVRGALISVPRHQVESGKAVGLSTVQLYRYVLLPQS
                     VHLMIPATINLMTRIIKTTSLLLLISVVDVINVGQQIIEANSHRYQDGAFWIYGFIFIL
                     YFILCYPLSRLARRLERRGKAGANG"
     CDS             complement(9289..9948)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 61.7; E-value: 2.5e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_12"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.3e-19, bitscore:
                     61.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWTVVQNSLPMFEKGFWLTLRLSFFGIIGAGVLGLICSFIQYFK
                     VPVLRKLVSAYVELSRNTPLLIQLFFLFYGLPQVGIKFSAEVCGIIGIIFLGGSYMAEG
                     FSGGLAGVSKTQIESGLAIGLSRFQLARYVIFPQGLMLSVPAFAANVIFLIKETSIFTV
                     LAIPELTNTALDLIGMYYNTNEYLFMLVVAYAIILIPLSILLTWLEKKVRYGTFGN"
     CDS             complement(10454..11956)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_13"
                     /sec_met_domain="DAO (E-value: 5.9e-11, bitscore: 33.5,
                     seeds: 522, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRQGKTDVILIGAGIMSATLGTLLKELTPDWEITVYEKLAKPA
                     EESSNEWNNAGTGHSALCELNYTPEKPDGSIDITKAVNVNEQFQLSRQFWSYLVSKGLI
                     RNPQDFIRPIPHMSLVEGEENVAFLKKRFKALSAHPLFEGMAFSDDPGQLKEWIPLVME
                     GRKSNEPVAATKSDAGTDVNFGALTRMLFDHLQRQNVEINYKHAVQDIKRTPEGNWEVK
                     VHDIEHNRIEYHTAKFIFIGAGGGSLPLLQKTGIPESKHIGGFPVSGLFMVCNNPEVIS
                     RHHAKVYGKAKVGAPPMSVPHLDTRYIDHKKCLLFGPFAGFSPKFLKTGSNLDLIGSVK
                     PNNVVTMLASGAKNVPLVKYLIGQLLLSDEKRLETLQEFIPDARLEDWDVVVAGQRVQV
                     IKDTEAGGKGTLQFGTEVVTAADGSVAALLGASPGASTAVHVMLEVIEKCFPDRKKAWA
                     PKIKEMIPSYGVRLAENPDLLHQIHAETAETLGLTEKEPAYR"
     CDS             12537..13634
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sugar_tr"
                     /gene_functions="transport (smcogs) SMCOG1007:sugar and
                     other transporter (Score: 56.4; E-value: 7.9e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_14"
                     /sec_met_domain="Sugar_tr (E-value: 4e-18, bitscore: 56.4,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTDTAAGLLTLSVAIMALGSLVIACTPGYSRIGVLSPVILVLAR
                     LVQGISLGGEYGTSATYLSEMASSGRRGFYSSFQYVTLVSGQLIALGVQIVLQLALNES
                     EMTSWGWRIPFVIGAIGALVVLWLRRTMDESEQFEEMGSETRKNAGTLKVLLNYPKAVL
                     TVVGLTLGGTVAFYTFTTYLQKFMVNTSGIDKETVSWINFIALFIFVVFQPLAGKLSDR
                     IGRRPLLIGFGILGTLLTVPIFLWLRETQNPVFAFLLMMAGLIIVTGYTSINAIVKAEL
                     FPTEIRALGVGFPYSLTVAIFGGTAEFIALWLKNAGVESAFFYYVAGCIAISLLTYLFM
                     AESSKHSRIEAELQSRPDSKNKIIT"
     CDS             complement(13627..13803)
                     /locus_tag="ctg44_15"
                     /transl_table=11
                     /translation="MPVHQASAVQISSFIQEGPNRIHDCIYGLVFGYSRSFILQGKIKQ
                     LQSATLQLFGFFR"
ORIGIN
        1 atccgtacaa tcaatatgag gtgataatca tgagagaaga gaaagaacgt gtagaaattc
       61 gtatgcctaa gacgatatta gaaaaattgg agcaatatca aaaagaaaat gggattccaa
      121 ctagaacagc cgcaatctta gaattgttga gaaaaggatt ggaaaaataa ctttggctaa
      181 agccaaccga aattcatctc ccacctactc attggtgcga ttcgcacctt cacattcctt
      241 gaggatggga gacttctttc ggaaaaccgt taaatcttac atcatgcggg tgataaaatg
      301 gagctaagac aggcattgca tcaatttttc cttgaaaaaa catggcaatt gacggaagac
      361 tggtacgcat cgctcgacaa aagcaccgtg cagggggttt atgcgtccac cgaccccgaa
      421 gtggttgcaa aactgaaaga gcaaaaccac gatttccacg tccagttttg tgaaatgttt
      481 ttaaaagatg aagatacatt tttacaccat tttgaaaagt gggtaatgaa cgttgcacag
      541 gatgaagagc atctttccac accgaaccac tttatttttc gcgagttctt ccacacgcag
      601 gaacaatatc tcgatctgtt tgattcattt gttgcagccc acgagggaaa atatacatac
      661 gaggaactga atttttggag aagggcgatc atccggacat tcgaacatgt catgctctgg
      721 tttatgaaag aaaaccacca ttattcctta aagcggttgg agtcccagca ggaaatgatt
      781 aaagagctga gttcccccgt cattatggtc ggcaaaaata ccgcgctgct gccgcttgtc
      841 ggggaaattg attccaaccg tgcgaaaatt attctggaaa aaacactcga acaatgcgca
      901 gaaaaaagcg ttctccttct atacattgat ttatccggcg tggtcgtcat cgatacgatg
      961 gtcgcccagc aaattttccg gctgattgag acgctgcggt taatcggggt aaaaagcatt
     1021 ctttccggca tccgtccaga ggtggcgcaa actgccattc aattgggcat tgattttaat
     1081 gacgtaacga tccactcaaa actggaactc atgtcggaat gatggcgttt tttcagccat
     1141 ccgggcatac cgttttggaa aatagagatc cggggaggag ccccctttga aacgcagccg
     1201 tcccgatatg gtttaagaaa atttttcttc ttgctatttt aagtccgtgc tgatacgata
     1261 gaagagcatg atttggaagg catatattca gcatcaggag tctttccaag cagataattt
     1321 tggccagtgg agtaaaggca tcggtgtgcc gggccaaatg ccgaatcggc aacttttggt
     1381 tgccttattg attgagtggg aaactcaaat tttataagtt ggttacttta caaccggtgc
     1441 ttgtgcacat caacttgtga aacgatcaat aagagtggta aaagtaatta tttgctatat
     1501 agactctgat cctataagaa tataaagctt tcttccatat tgtccacgga cttttatggc
     1561 aggcgtatat ctgtttatgc ggatatgcat gcttttttag gatgatgatt tcaagcaagt
     1621 gttgtgcgca cgtatgcgga ttgcacttgc tttttattat gcaaaaattc tatttgaagg
     1681 agacagaaga atgggaaaag cgttgattat cggggccggc ggcgtggcat cggtcgctgc
     1741 gcataaatgt gtccaaaaca gcgaagtctt tgaagaaatc tgcatcgcaa gccgcacgaa
     1801 atcaaaatgc gatgcgttaa aagcaaagct tgacggcgga aaaacgaaag tgacgactgc
     1861 acaggtcgat gccaatcacg tcgatgaact ggttgcttta attgaaaaag tgaaaccgga
     1921 tgtcgtcatg aatctggcgc tgccttacca ggatttaacc atcatggaag cctgccttca
     1981 aacaaaaaca aactatctcg acaccgcgaa ctatgagccg gaagacacgg caaaatttga
     2041 atacaaatgg caatgggcat accgcgaacg ttttgaagaa gccggcatta ccgcccttct
     2101 cggcagcggc tttgacccgg gcgtaacagg cgtattttcc gcttatgccc tgaaacacca
     2161 ttttgatgaa atcaattata ttgatatttt ggactgcaat gccggcgacc atggctatcc
     2221 gttcgcaaca aacttcaacc cggaaatcaa catccgcgaa gtttccgcca acggcagcta
     2281 ctgggaaaac ggcaaatgga tcgaaacaaa accgatggag atcaaacgcg tgtatgattt
     2341 tcctgaaatc ggcgaacgcg acatgtacct gctgcaccat gaagagctgg agtcgcttgc
     2401 cgcaaatatc cctggcatta aacggatccg tttcttcatg acgtttggcg aaagttacct
     2461 gacacatttg aaatgcctgg aaaacgtcgg catgacttca attgagccga ttgaatttga
     2521 aggcaaacaa atcgtgccgc tgcaatttct gaaagctgtg ctgccggatc cggcttccct
     2581 cggcccgcgc acaaaaggga aaacgaatat cggctgcatt ttccgcggca aaaaagacgg
     2641 caaggacaaa acctattacc tttacaatgt gtgcgaccat gaagcctgct acaaagaagt
     2701 cggctcgcag gcggtatcgt acacaaccgg cgtgccggcg atgatcggcg cgatgatgct
     2761 gatccagggc aaatgggaca gaaaaggcgt ttataatgtg gaagagttcg atcctgatcc
     2821 gttcatggaa gctctgaaca aatggggcct gccgtggaaa gaaagctata atccggagct
     2881 tgtcgactga tgcgatttga agaactgccg acgccttgct atgtagttga tgaacaaaag
     2941 ctcgaagaca atttgaaaat tttaaacggc gtgatgaaac ggaccgggtg taaaattgtt
     3001 ttggcgcaaa aagctttttc gatgtttgct ttgtacccgc tcatcggcaa atacttgagc
     3061 gggacaacag caagcggctt gtatgaagcg cgcctcgggc atgaggaaat gggaaaagaa
     3121 aaccatattt tttccgccgc ttaccgtgaa gatgaaatcg atgagatcgt ctcgatttgc
     3181 gatcatgtta tttttaattc attttcacag cttgagaaat tcaaaggccg cgtgcttgca
     3241 ggcgggaaaa aggcgggcct gcgcatcaat ccggaatgct cgacacagac cgggcatgca
     3301 atttatgacc cttgttcgcc gggctcgcgc ttcggtgtga cgcaggaaca gttccgccct
     3361 aatcttctgg acggcgtaac cggcctccat ttccacacgc tctgccagca aaatgcggac
     3421 gatctggaga caacgctgaa tgccgttgaa gaaaagttcg gggaatggct gccgcaaatg
     3481 gaatggatca atttcggcgg cggccaccat attacgaggg aaggctatga cattcccttg
     3541 ctcgaaaaat gcatcaagcg gatgcaggac aagtacggtt tggaagtcta ccttgagccg
     3601 ggcgaagctg ttgctttaaa tgccggctat cttgtcacga cagtgcttga cacagtgaaa
     3661 aacggcatgg acatcgcgat cctcgatacg tccgcctcgt gccatatgcc ggatgtgctg
     3721 gaaatgccgt accgcccgcc gctcatcggg gccggggagc cgggcgaaaa accgtatacg
     3781 taccggcttg gcggccaaac atgcctcgcc ggcgatacga tcggcgatta ttctttcgat
     3841 aagccgctta aagaaggcgt tcgccttgta tttggcgata tggccatcta caccatggtg
     3901 aaaaatacca cctttaatgg catgccgctt ccggccatcg cgatccaata taaaaacggc
     3961 gactgcgcaa ttgtccgtga attcggctat cacgacttta aaatgagact cgggtgaata
     4021 cctgcattac ccgggctaag tggaaacaat atagacgagg gagaaaagcg aaaccgccgg
     4081 cagcctatcc gtggctgatg atgctttctg ctgcagatta ccggaaaaag acggttaaca
     4141 cggacatttt gcaggaactg gaggaatggg cgatgaatgg gtaggaagtg cttgacgcaa
     4201 tcaaagagtg ggagaatttg agtgccaatc gggaaaacaa agtattgtac gaagcccggc
     4261 tgaaatttta cgcgaccagc tcgcgaatat ccgcggtgaa agagaggaag ggctcagaga
     4321 agggattcaa aaagggattg aagaaggggt acaaatagca atcaaaaaat gctgagcaaa
     4381 ggcaccccac ccgaaacgat cgcagatatg cttgattatc cgcttgaaga aatcaaaaaa
     4441 acccagcggg aattagagcg gggtagctaa ctgaatcgcg cgcccgccgc ttccaaacgc
     4501 aagggggcat ttccaatgcc ggactggcgg cggaatggcc ccctttgcta tcttggttgc
     4561 atgcttccgg cttccctttt ttccacaaca ttgttataat aatatttgga agcttccaat
     4621 aacctggggt ttccggcatg cccatacgca aacccggaca gctatcttct ttagtatttt
     4681 tactatttga agccattagg tgttcttttt gtgttgccta aatttcaata aatggaggga
     4741 tagcaatgaa aaagcgggca attgtgtatt gcgaaaacca atttggcaca acagatggca
     4801 aaacagcaaa cgggctcatc cgtgaacccg ggaattacac cattactgcc gtcattgaca
     4861 gcagcaaaca cgggcaggat gccggcatgc tcctcgacaa caaatggagc ggcattccgg
     4921 tttgcaaaga cctggaagac gcgctcatcc actccggccc gaaaccggat gacttcattt
     4981 tcggcatcgc gccggcgaac gcctttttaa agccggaaga aagaaaagtc atcctgcagg
     5041 caatggaagc cggattgaac atcattaacc cgctccagga attcttaacc gatgatgaag
     5101 aaatggtggc ccatgcaaag gcttgcggtg tcacgatccg cgatatccgt aaaccgcggc
     5161 cgaaaaaaga atggactttg tttaccggag aaattttgaa aatgaacacc cctgtcgttg
     5221 ccgtgctcgg gacagacggg gcctgcggaa aacggacaac cgccaaatgc attgaaaagg
     5281 cattcatgga aaaaggctac cgcccggcat ttatcgcaac cgggcagaca ggtttgatcc
     5341 agggcgccaa gtacgggttt gcgatggatg ctttcccgct ccaatattta atcggcgaac
     5401 tggaacgcga aattttgcgg gccaataaac aagaacaccc ggatattatc atcgtggaag
     5461 gccagggcgc gctcagccac ccggcatatg caagctcaac cggcatttta aaaggagcaa
     5521 ggccgcaagc agtcatttta cagcacgccc cgaaacgaaa atatttatcc gattttccat
     5581 ttgccgaagt gccgaaagtg gaagatgaaa tcagcctgat tgaacatttc ggaaagacaa
     5641 aagtcatcgg cattacgctc aaccatgatg gaatggcaga cagcgaactg gaagacacca
     5701 tccgccgcta tgaagaaact taccatcttc cggttacgga tgttttaaaa accggcacag
     5761 acaaaatcat aaacgccctg atcgatttct tcccttccct gaaaaaggca gtggtttcct
     5821 gatggccgtt ctgccacggg tggaaatcaa tctggagaag atccggcata atgcggaaac
     5881 attaaaacaa ttattcggga ggaaaggaat cagcattaca ggcgttgtga aaggtgtcgc
     5941 agccgattta aaaattgccg gcaccctggt ggatgcaggc atcaaaagcc tcgcagactc
     6001 gaagattgca aatatcgaaa aaatgagaaa agcgggaatc aaggcggatt tgattttgct
     6061 ccgtgccccc gggatcagcg aagcggaaaa aacggtccgg tttgcggata tcagcatgaa
     6121 cacggagctg gatacgatcc gcgcattatc cgctgaagcg gtgcggcaac agaaaaccca
     6181 taaaatcatc ctgatggtgg aaatgggaga tttgagggaa ggcatattat taaaagatgc
     6241 ccctgctgtg atcagagaaa tattaacctg ccccgggatt gaactggccg gaatcgggac
     6301 aaattttgcc tgctttggag gcgtgctccc gaccgaacag aagatgcagg cgttttcccg
     6361 gtttgtccat gccatgcagg agctgttttc cctcaaactt ccttatgttt ccggcggcaa
     6421 ctccgccaac tacaactggg ccgtaaaaac aaaagacgcc ggggccgtaa acaatgtgcg
     6481 gctcggcgag tccattttgc tgggccgcga aacatcaggc gggcatacca ttccgtcttt
     6541 atatcaggat gccttttgct ttgttgccga agtcatcgaa tcaaaaatca aaccttccgt
     6601 gccgtatggg acaatcggca aaaatgcatt cggggaacag gtcaccttta tcgacagggg
     6661 caacagaagg cggacgattg tcagtgcagg gcggcatgat gtgcttgttt caggccttac
     6721 ccctgtccgg ccgttccata tcattggctc aagcagcgac catatcattt tggatacaca
     6781 aaatgcggtt ctcgtgccgg gcgatgaggt gagattttat atggactacg gcgcgatgct
     6841 gagagccatg acgtctccgt atgtttataa aacgtacgtc catggtgcgg ccacaaccaa
     6901 gccttacaaa caacagtttc tgctttcgcg cggaacaaag caaagccggc ccgcggaaac
     6961 cgaaaaaagc cccgccaatt aaagaaaagc aggctgcaaa aacggcagcc tgcctttttt
     7021 acttcgttat aatgatgtct tccgcacgga tatcactgcc aaaatatggc gccagatttt
     7081 tgttgtaatc acttttgaaa aagccattgt tgtttaactt cgtaatttct ttgttcatcc
     7141 aattgaggag cgattgattc ccttttttca cagcaggggc aatatattgg ttcggcccga
     7201 gcgttttaat gccaaccgta taatccggat ggtttttcac ccaggcatac aggtaggaat
     7261 tgtcgtccgc cagtgcaacg gcccgcccgt ttttaagcgc attgaactgt tctgttttgg
     7321 aatcgtactt ttgcaatttc acatcttttt gtttgcttgt aaaatagttt tccgcagtgg
     7381 tgcccttgtt gacgatcaaa gacttgcctt ttaattggct gacacttgtg accggctttt
     7441 tcttcggtga aacaacaccg atggaaactt tcatgtacgg cttggcaaaa tcaacaactt
     7501 gcttccgttc cggtgtgact gtaaaattcg ccagaaccag atccacttta tttgatttca
     7561 atgcatccac acggctgttg gcattcactt gcacgaattt cacttttacg ccaagatctt
     7621 tggcaacttg tttggcgagc gcaacatcat atccctggcg ttgcccgttt ttatcgaccc
     7681 atccgtatgg cggaagatcg ccgaatacgg caattttgat cgtgccgttt ttcttaatgg
     7741 ctgaaacact ggacggattg ctgcttgaag aattgccgga acttttgccg cagcctgcaa
     7801 gcgccagcga caaaattaat aaaaatgctg aaaccaaacc aaacaaacga tgctttttca
     7861 tggtctaacc ctccaaaata tttttctttt aaaaatccat gctttccaga aaatttttcg
     7921 cccgctctgt ctgcggtttt gtgaaaaatt ggcgcccggg ggtttcttcg agaatcttcc
     7981 cgtcttccaa aaacaagatt ttatccccga tttgccgggc aaaattcatt tcatgcgtga
     8041 cgacaatcat cgtcatcttt tctcttgcca accgcaggat gatctcgagc acgccgcgca
     8101 ccatttccgg gtcaagcgag gcggtcactt catcaaacag catcagcttc gggttcagct
     8161 caagcgcgcg gacaatcgcc acccgctgtt tctgcccgcc ggaaagctgg cgcggatagg
     8221 cattggcata ctgctccatg ccgacttcct ttaacaggcc cattgcctgg cgcgccgctt
     8281 cgtctttttt ccgtttctgg actttcactg caccgagcag gatgttttcc aacaccgtca
     8341 tattcggaaa cagatcatag ctctggaaaa ccattccgat ctgctgcctg agcctgcgcc
     8401 aatttttcgg cgacggccgc acggtttccc cattaaacag aatggtgccg ccctggaagg
     8461 cttcgagacc gtttaagcag cggatcaatg tactttttcc cgatcccgac ggcccgagga
     8521 gaacaacaac actgccttcc tccacttcga aagagatatc ctccagcact tgtttttcac
     8581 cgtacgattt ttttaaatgt tcgactttca gtaaaggttc agccattagc ccctgctttg
     8641 cccctccttt ctaaccgcct tgccagccgg gaaagcggat agcataaaat gaaatacagg
     8701 ataaatataa aaccgtatat ccaaaacgcg ccatcctgat agcggtggct attcgcttcg
     8761 atgatttgct ggccgacatt gatgacatcc actacgctga tcaatagcaa aagggaagtc
     8821 gtcttaatta ttctggtcat caggttaatg gtcgccggaa tcattaagtg gaccgattgc
     8881 ggcagcagca cgtaccggta aagctgaacc gtgcttaaac cgaccgcttt tccggattcc
     8941 acctgatgcc ttgggacaga aatcagcgca ccacggacaa tatcgctcat ttcagcagcc
     9001 atccacaggc tgaagacaat cgtcccgacc gtatccgcct tatagttgat gttaaagctt
     9061 tgcggcagaa tatagtaaaa caaaaataac aggacaatcg tcggcacgat gcggaaaaac
     9121 tccaaataca gcctgagtaa aaggcggagc aacggattgt gcaatgtcct taaaaccccc
     9181 agcacgatgc cgaggatacc gccgaaaacg atggacagaa aagcaatttt tgccgatacg
     9241 tataatccac ccagtaaacg taaaaagttg gctccttcaa aaaagatatt aattcccaaa
     9301 tgtcccataa cgcaccttct tctccagcca tgtcagcaag atggacaatg gaattaaaat
     9361 gatggcataa gccacaacga gcataaacag atactcattc gtgttgtaat acatcccgat
     9421 caagtcaagt gccgtgttgg tcagttccgg aatcgccaac acggtaaaga tagaggtttc
     9481 cttgattaaa aaaatgacat ttgcggcgaa tgccgggaca ctgagcatca atccctgcgg
     9541 aaagatgacg tagcgtgcca gctggaacct gctcagaccg atcgcaagcc cggactcaat
     9601 ctgcgttttc gaaacgcctg caagccctcc ggaaaaccct tctgccatat aactgccgcc
     9661 aagaaaaata atcccgataa tcccgcaaac ctcggcagaa aatttgatcc cgacttgcgg
     9721 aagcccgtaa aaaaggaaaa ataactggat caataaaggc gtattgcggg acagttccac
     9781 ataggccgat acaagcttcc gtaaaaccgg caccttaaaa tactggataa aactgcatat
     9841 caagccaaga acaccagccc cgataatgcc gaaaaaggaa agccgcaaag tgagccagaa
     9901 tcctttttca aacatgggca agctgttttg cacaacggtc cagtccatct cacccctcct
     9961 attttggaaa attctcttca atccaggcgg gcttgcgcca gccgtccggt atgtatggcg
    10021 ttgctgtccc gaatcaggtg cttgcgcgtt taaaggccgg acgacaaaaa gccgtttcct
    10081 aagaaaacga ctgtcctttt tcaggtattg ctgcagtttt cttatcttga tagacgatca
    10141 tgaactgtac tattatgatg ccggtttcca aggacagccc ttccgccgcc cgggataaga
    10201 aattttcagc attttagcaa catctttatt ttactgaacg ccgggacaaa aatcaatata
    10261 ttcctatcga cttgataggg ttttctttgc atagcaccca aaaaaaacag catgccaaag
    10321 ttgttcctcc gcttgcaccc gtactgcttt ccggctgcct gcaaaatgaa tgccggttaa
    10381 gacgcgttac agccaaaaaa aggccttcaa tccgctttag gatcaaaggc ccttcatttt
    10441 agcgctccac gcgttaccgg taggccggtt ctttttccgt caggccgagc gtctctgccg
    10501 tttcagcgtg aatttgatgc agcagatccg gattttctgc aagccgcacg ccataagaag
    10561 gaatcatttc ttttattttt ggtgcccatg cttttttccg gtccgggaag catttttcaa
    10621 tgacttcgag cataacatgg acagcagtag aagcacccgg cgaagcgccg agcaatgccg
    10681 cgactgaacc gtcagcagct gttaccacct ctgtaccgaa ctggagcgtg ccttttccgc
    10741 ctgcttccgt atctttaatc acctggacac gctgcccggc tacgacaaca tcccagtctt
    10801 ccaatctcgc atccggaatg aattcctgca gcgtctccag gcgtttttcg tctgacaata
    10861 gaagctgccc gatcaaatat ttaacaagcg gtacattttt tgccccggac gcaagcatcg
    10921 ttacgacatt attcggcttc acagaaccaa tcaggtctaa atttgaccct gtttttaaaa
    10981 acttcggcga gaagccggca aacgggccga acagcaaaca ctttttatgg tcaatatatc
    11041 ttgtatccaa atgcggcacg gacatcggcg gcgcgccgac tttcgctttg ccgtacactt
    11101 ttgcatggtg gcggctaatg acttcaggat tgttgcacac cataaataac ccgcttaccg
    11161 gaaaccctcc aatatgtttg gactccggaa tgccggtttt ttggagcaac ggcaagcttc
    11221 cgccaccggc accgataaaa ataaatttcg ccgtatggta ttcgatcctg ttgtgctcaa
    11281 tatcatgcac tttcacttcc cagtttcctt ctggggtgcg tttaatatcc tgaacggcat
    11341 gcttgtagtt gatttcgaca ttttggcgtt gcaaatgatc aaacagcatg cgggtcaagg
    11401 cgccaaagtt gacgtccgtc cctgcatcgc tttttgtcgc cgcaaccggt tcattggact
    11461 tcctgccttc catcacaagc ggaatccatt cctttaattg cccgggatcg tcggaaaacg
    11521 ccattccttc aaaaagcgga tgggctgaca gcgctttaaa tcgctttttt agaaaagcaa
    11581 cgttctcctc cccttctaca aggctcatat gcgggatcgg ccggataaag tcctgcggat
    11641 tgcggatcag ccccttgctg accaggtagg accagaactg ccttgaaagc tggaattgtt
    11701 catttacatt tacagctttt gtaatatcta ttgagccgtc cggtttttca ggcgtataat
    11761 tcagctcaca taatgccgag tgcccggtcc ccgcattgtt ccattcattc gaactttctt
    11821 ccgctggttt tgccagcttc tcatatacgg tgatttccca atccggggtc agttctttca
    11881 gcaaggtgcc cagcgttgcg ctcataatgc cggcaccaat taagatgacg tctgtctttc
    11941 cctgtctgat gctcatgatt accttctcct tatccctata tttgctaata ttattccgga
    12001 cacactgcct ctttttcaga acaaggcagt ccccgggaaa acgttttaca agtcttaata
    12061 tcataatatc atattttatg ataattcttt agaataatga tacacaattt gacaatggaa
    12121 atatcaggaa acctttttat ttgctgaatg attcattctt cattttgctt aaaaatataa
    12181 tataatgaat cttgtaaata gaaattttac tggtatattt cttgcatttg ccaaaggggg
    12241 atgccaggag atatttttca cggattgaag acggaatttt cattttacaa agggggaaga
    12301 caaattggca caaacaaccg gacgcacatc cagacatgtg actgctaaca tctttaaagg
    12361 atcacttggc aatctgatcg aatggtatga ttggtatgtt tattctgcgt ttgcggttta
    12421 tttttcatca gagttttttc cggaggggaa ccaaactgtc cagttattga atacagccgg
    12481 gatttttgcc attggttttc tgatgcggcc gctcgggagc ctgatcatgg gccggtatgc
    12541 agaccgatac ggccgcaggg ctactgaccc tttccgttgc cattatggcg ctcggttcgc
    12601 ttgtcattgc ctgtacaccg ggatacagca ggattggtgt gctgtcaccg gttattttgg
    12661 tcctggcccg gcttgtgcag gggatctcgc tgggcgggga atacggcact tctgctacct
    12721 atttgtccga aatggcaagc agcggccgcc gcggcttcta ttccagtttc caatatgtca
    12781 cgcttgtatc ggggcagttg atcgcacttg gtgtccaaat tgtgctccaa ctcgcattaa
    12841 atgaaagcga aatgacctcg tggggatggc ggatcccgtt tgtgatcggc gcgattggcg
    12901 cattggtggt cttgtggctg cgccgtacga tggacgagtc cgaacaattc gaggagatgg
    12961 gatcggaaac gcggaaaaat gccggaacgc tgaaggtcct attgaattat ccgaaagcgg
    13021 tgctgaccgt tgtcggcctt acacttggcg gcactgtcgc attctacaca ttcaccacct
    13081 atctgcaaaa atttatggtg aacacgtccg gaattgataa agaaaccgtc agctggatca
    13141 actttattgc ccttttcatc tttgttgttt tccagccgct tgccggaaag ctgtccgacc
    13201 ggatcgggcg caggccgctg ttaatcggct tcggcattct cgggaccctt ttgaccgtac
    13261 cgatattttt atggttgaga gaaacgcaga acccggtttt tgcttttctt ctcatgatgg
    13321 cagggctgat cattgtaacc ggctatactt ccatcaatgc cattgtgaaa gctgagctgt
    13381 tcccgactga aatccgcgcg cttggtgtcg ggtttcctta ctcattaact gtcgcaatct
    13441 ttggcggaac agccgaattt atcgcgcttt ggctgaaaaa tgccggcgtg gaatccgcct
    13501 ttttctacta cgtcgccggc tgtattgcca ttagcctgct cacttattta ttcatggccg
    13561 aatcctcgaa gcattcccgg atcgaagcag aacttcaatc ccgcccggat tcgaaaaaca
    13621 aaattatcac ctgaaaaagc caaacagctg cagcgtggca gactgcagct gttttatttt
    13681 tccttgcaag atgaaagacc gggaataccc aaaaaccagc ccgtaaatgc aatcgtgaat
    13741 acgattcggg ccctcctgaa tgaaggatga tatttggacc gcgcttgcct ggtgcaccgg
    13801 cattatggcc atcgcttact tcttcgctaa taaagcattt aaacgccagt tacggtaggc
    13861 ctatcatgag gaaggtcagt catacgctgt gatcaatgca ttggcttcca ttccgggaag
    13921 attttaaagc atcgcctcca aacagggggg catctcgatc attttccagg ctggggtttt
    13981 ccacacataa atcaaaaaaa gcagatgctt ttcttcc
//
