LOCUS       c00061_gnlPro..         4058 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FMKPLICD_62.
ACCESSION   c00061_gnlPro..
VERSION     c00061_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:36:25
            Original ID  :: gnl|Prokka|FMKPLICD_62
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4058
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4058
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[137:2150]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      138..2150
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..4058
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4058
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(138..1289)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_1"
                     /sec_met_domain="HGD-D (E-value: 7.7e-89, bitscore: 286.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIKDLPEVFEEFAEQRKNSFLAIKKIKDQNIPVIGSYCTYFPQ
                     EIAMAMGAASVGLCSMSDETIPVAEQTLPKNLCPLIKASYGFAVTDKCPFFYFSDVVVG
                     ETTCDGKKKMYEFMSEFKDVFILELPHKQTEAALQYWKSEIIRFKEYLEKKFEVEITEE
                     KLREAVRISNEGRRALKDFYELMKQDPAPMKGENLYNVLYGTTFKFDRSKVPAEIDALT
                     VKLKEEYAAGKNEGKKHRILITGCPMGGATMKVVKAIEENGGVVVAFENCSGAKSVDRL
                     IDENDPDIYEAIARRYLNIGCSVMTPNPNRFELLNELIDEYQVEAVVEMTLQACHTYNV
                     EAGKVGRFVREEKKIPYLHVETDYSQSDVGQLNTRIAALIEML"
     CDS             complement(1389..2150)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: FGGY_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="FGGY_C (E-value: 1.5e-08, bitscore: 22.7,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.4e-51, bitscore:
                     161.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYYVGIDIGSTASKTVVTGDREMKFVLPTGWSSKETASEIASRLL
                     DQGIDVMSEGVRVAATGYGRVAVDYADFVITEITCHGRGGRELAGNECAIIDVGGQDTK
                     VILIDQGMIQDFLMNDKCSAGTGKFLEIMANRLGVTIAELFDLAEQGTVVPISSLCTVF
                     AESEVISMIGEGRSREDIAAGVVNSVAEKVAQLARRKQLPGTVLLTGGLSECPYFAEIL
                     SEKLGCAVEAMKDGRYAGAFGASLLAGEKKK"
     CDS             complement(2478..3446)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3.9e-26, bitscore:
                     80.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVELVYIATPHSHHYLHAKMCLEVGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDAEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
     CDS             complement(3623..4057)
                     /locus_tag="ctg61_4"
                     /transl_table=11
                     /translation="YCKTNNVIKKEKLLLKRNHRLTNIRKNYLNQTISEIVNRKPRFIC
                     IEDLNVSGMMKNRHLSKAVQAQGFFGFRKQLEYRCSDKGIQLIVADRFYPSSKLCSCCG
                     NIKKDLKLSDRVYRCACGNMIDRDFQASINLKTYGEQFAG"
ORIGIN
        1 ctgacgcacg gcaaagatat ctgacgcagg atttcacact ctgatgggct ggattaagat
       61 gcattatttc aaaggattgc tataataaaa tacatacaat tcgacatttt tcgtataatc
      121 ttataatacc ttcacagtta taacatttct atcagagccg caatacgtgt atttagctgt
      181 ccaacatcag actgagaata atctgtctcc acatgcagat aaggaatctt tttctcttct
      241 cttacaaatc tgccaacttt accggcttcc acattataag tatgacaggc ctgaagagtc
      301 atttccacaa cagcttctac ctgatactca tcgatcagtt catttaacag ttcaaaacgg
      361 ttcggattcg gagtcataac agaacagccg atattcagat aacgtcttgc aattgcttcg
      421 taaatatccg gatcattttc atcaatcagt ctgtctacgc tctttgcacc ggagcagttt
      481 tcaaaagcaa ctaccacacc gccattttct tcaattgctt ttactacttt catggtagct
      541 ccgcccattg gacatccggt gatcagaata cgatgtttct ttccttcgtt tttgcctgct
      601 gcatattctt ctttcagctt cactgtcagt gcatcaatct ctgccgggac tttggaacgg
      661 tcaaacttaa aggtagttcc atacaataca ttataaagat tctcaccctt cattggagcc
      721 ggatcctgtt tcatcagttc atagaaatct ttcaaagcac gacgtccctc attgctgatg
      781 cggactgcct cacgaagctt ctcctctgtg atctccacct caaatttctt ctccagatat
      841 tctttgaaac ggataatctc actcttccag tactgaagtg cagcctctgt ctgtttatga
      901 ggaagctcca gaataaatac atccttaaat tcggacataa attcatacat ttttttcttt
      961 ccgtcacagg tagtttcacc aactacaaca tctgaaaaat aaaagaatgg acatttatct
     1021 gtcactgcaa acccataact ggccttgatc agtggacaga gatttttcgg caatgtctgc
     1081 tcggctaccg ggattgtttc atcagacatg gaacataaac ctacagaagc agctcccatg
     1141 gccattgcaa tctcctgtgg aaaatatgta cagtaagaac caattaccgg gatattctga
     1201 tccttaatct tcttgatagc aagaaatgaa ttcttcctct gctccgcaaa ctcctcaaat
     1261 acttctggta aatctttaat tatttccatc tttgtacctc atctttctat cgtttttata
     1321 ttatttttta cttctttcat accattcgcc aactgttgca gtccttatta tcctctacag
     1381 ttgattattt atttcttttt ttctccggca agcaatgatg ccccaaacgc tcctgcatat
     1441 cttccgtctt tcatagcttc aacagcacat ccaagttttt ccgaaagaat ttctgcaaaa
     1501 tacggacatt cactcaatcc tcccgtaaga agcactgtcc ccggaagctg ctttcttctg
     1561 gcaagctgcg caactttctc cgctacagaa tttaccactc ccgcagctat atcctctctg
     1621 cttcgccctt caccaatcat gctgattacc tcagattccg caaataccgt acacaacgaa
     1681 ctgatcggta ccacagttcc ctgttctgcc aggtcaaaca gttccgcaat ggtaactccc
     1741 agtcgattcg ccataatctc cagaaacttc ccggttccgg cagaacattt atcattcata
     1801 agaaaatcct ggatcattcc ctgatctatc aagattactt tcgtatcctg accacctaca
     1861 tcaataattg cacattcatt tcccgccagt tctctgccac ctcttccatg acaggtaatc
     1921 tccgtaatca caaaatccgc ataatccaca gctacacgcc catatcctgt agctgctaca
     1981 cgaacccctt cactcattac atcaatcccc tgatccagaa gccttgaagc aatctccgaa
     2041 gccgtctcct tactgctcca ccctgtaggc agcacaaatt tcatttccct gtcaccagtc
     2101 acaactgtct tcgaagcagt cgaaccaata tcaattccaa cataatacaa cttttctcac
     2161 ctgctttttt gggtattttt atccattctg tttactgtaa cttctattat accctttccc
     2221 attaataatc aaaaattcaa aaatacaata aaagcaggag atttatttaa aaaagctata
     2281 aatgattttt accccacgaa caagcaatga cacacgacag ataatgataa aatcctcttt
     2341 ataaatttat ctggtaaaat caagacacaa taaatttttt tgttacattt ccattatagc
     2401 agaaaagaaa aaccagtaac gtttcgggta tatgtcaaaa cattactggt cttttttata
     2461 agattattcc acacttttta ttcgatacag ggaatctcat aattccagga tttacggatg
     2521 tcgtccatga ttttcatgat ccttattgtt tccgcatgag gcatttccgg acactccgtt
     2581 tttccctcat gaattgcttt catgcaggat tctacctcat attcatatcc tgagatctgt
     2641 tccggcacaa cataagaagc cacttcttta tgttcggcat caaacactgt aatcttttcc
     2701 ggattattga tattctgcac ctgcatatat cctctggttc cgaaaatact tcccattctg
     2761 tctgagattt ctcttgctcc acactgaagg gttgccatgc ggtctccctc aaacaccatg
     2821 gcaatgctgt ccagaatatc cactccattc tgaaagattg cagtagcctt tacatccttt
     2881 accttatcgc caagcaccat ggaggcaaaa ttaattggat atactcctac atccagaaga
     2941 gcacctcctg caagctccgg tttacggata cgttccacat gacttactgt atagctgaga
     3001 ttcgcggtaa ctgccgtaac ttctccgatc acaccgcttt caataatatc gttaatcatc
     3061 tttctggacg gcatatatct tgtccagatt gcttctgtga tcagaagctt tttctctttt
     3121 gcaagatcaa ataatttctg tgcctgctct gcatttacag taaatgcctt ttcacaaagc
     3181 acatgctttc ctacttccag acacattttc gcatgcagat aatggtgtga atgaggggtt
     3241 gcgatataaa ccagttcaac ctcatcatct gccagcattt cctcatagga tccatatgct
     3301 ttttttactt catatttctg tgcaaatacc cgggcacgtt ccagatcacg ggcagcaacc
     3361 gcatacgcct ccacatcttt cattcctgcc actgttttcg ccatagtaga agcaatgcct
     3421 cctgctccca gaatacctaa cttcatttta ctgtccgtta ctgaaaactt ataaaaagtt
     3481 ataaacttct atgtttcatt cctacttcaa cgagtatgct tttgatgata taaatatcta
     3541 tctactcaca agttcttgta ctctccatag gcgtaaattc cggactaacg tatccgtaca
     3601 tatttgcatt aacgtttctg tgtcagcctg caaattgttc tccataagtc ttgagattta
     3661 tagatgcctg gaaatctctg tcaatcatat tcccacacgc acatctataa actctgtcag
     3721 ataacttcag atcttttttg atgtttccac aacagctgca aagctttgat gatggataaa
     3781 accgatcagc cacaataagc tggatccctt tatcgctaca cctatattca agctgttttc
     3841 taaacccaaa aaatccctgt gcctgaactg ctttggataa atgtctgttt ttcatcattc
     3901 cgctgacatt cagatcttca atacatataa atcttggttt tcgatttacg atctccgata
     3961 tggtctgatt taaataattt ttacggatgt ttgttaatct gtgatttcgt tttaataaaa
     4021 gtttttcctt tttgatcaca ttatttgttt tacagtaa
//
