LOCUS       c00128_gnlPro..        16233 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FMKPLICD_131.
ACCESSION   c00128_gnlPro..
VERSION     c00128_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:36:25
            Original ID  :: gnl|Prokka|FMKPLICD_131
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16233
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16233
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2696:6233](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2697..6233
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16233
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16233
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(23..1663)
                     /locus_tag="ctg128_1"
                     /transl_table=11
                     /translation="MISANNITLRVGKKALFEDVNIKFTEGNCYGLIGANGAGKSTFLK
                     ILSGQLEPTNGDVVITPGQRLSFLQQDHFKYDAYTVLDTVIMGNKRLYEIMKEKDAIYA
                     KADFTDEDGIRASELEGEFAEMNGWEAESDAATLLNGLGIETDLHYSQMADLTGSQKVK
                     VLLAQALFGNPDILLLDEPTNHLDLPAIEWLEEFLINFDNTVIVVSHDRYFLNKVCTHT
                     ADIDYGKIQLYAGNYDFWFESSQLLIKQMKEANKKKEEKIKELQEFISRFSANASKSKQ
                     ATSRKRALEKIQLDDMRPSSRKYPYIDFRPNREIGNEVLMVENLSKTIDGVKVLDNISF
                     TLGHDDKVAFVGANEQAITTLFKILVGEMEPDEGNYKWGVTTSQAYFPKDNTAEFDNDL
                     TITDWLTQYSEIKDATYVRGFLGRMLFPGEDGIKRVRVLSGGEKVRCLLSKMMISGANI
                     LILDEPTNHLDMESITALNNGLIKFPGVILFTSHDHQFVQTTANRIMEILPNGTMIDKI
                     TTYDEYLASDEMAKKRHVFEINEEDASDN"
     CDS             2015..2422
                     /locus_tag="ctg128_2"
                     /transl_table=11
                     /translation="MFITRECDYAVRVVRALWGESRLSVSDICEKEAITAPFAYKILKK
                     LQKAEIVKGYRGVHGGYSLNRGLDELTLYEVYSAIDPDMFIIECLDPKYNCVRDGQDGL
                     PCLVHRELLSVQDELISLLKRKTIQQIMEEA"
     CDS             2697..6233
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg128_3"
                     /sec_met_domain="PFOR_II (E-value: 1.3e-19, bitscore: 61.3,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.6e-83, bitscore: 270.7,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.5e-30, bitscore: 97.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-13, bitscore:
                     41.9, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.4e-12, bitscore: 38.6,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.4e-06, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.3e-22, bitscore: 70.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKMKTMDGNHAAAHASYAYSDVAAIYPITPSSVMAEATDEWAT
                     QGRKNIFGQEVQVTEMQSEAGAAGAVHGSLAAGALTTTYTASQGLLLMIPNLYKIAGEQ
                     LPAVFNVSARALASHALSIFGDHSDVMACRQTGCAMLCESSVQEVMDLTPVAHLAAIKG
                     KVPFINFFDGFRTSHEIQKIETWDYEDLKDMADLEAIAEFRNHALNPNHPCQRGSAQNP
                     DIFFQAREACNPYYDALPAVVQEYMDKVNAKIGTDYKLFNYYGAADAEHVIVAMGSVND
                     TIEETIDYLAAAGKKVGVVKVRLYRPFCAQALIDAIPESVKQITVLDRTKEPGALGEPL
                     YLDVVAALKDSKFGGVKVFSGRYGLGSKDTTPAQIVAVYENTAKEKFTIGIVDDVTNLS
                     LETGAPIVTTPEGTTNCKFWGLGADGTVGANKNSIKIIGDNTDMYAQAYFDYDSKKSGG
                     VTMSHLRFGKKPIKSTYLIHKANFVACHNPSYVNKYNMVQELVDGGTFLLNCAWDMEGL
                     EKHLPGQVKAFIANHNIKFYTIDGVKIGIETGMGPTRINTILQSAFFKLTGIIPEEQAI
                     DLMKAAAKATYGRKGDDVVQKNWAAIDAGAKQVVEIQVPESWKNAEDEGLHMTHATEGR
                     QDVIDFVNNIQAKVNAQEGNSLPVSAFKDYVDGTTPSGSAAYEKRGIAVNVPVWNPENC
                     IQCNRCAYVCPHAVIRPVALTAEEAANAPEGMKTLDLTGMKEYKFTMSVSALDCTGCGS
                     CVNVCPGKKGAKALAMENLEASADEQKYFDYTVKLPVKEDVIAKFKEATVKGSQFKQPL
                     LEFSGACAGCGETPYAKLITQLFGDRMYIANATGCSSIWGNSSPSTPYTVNAKGQGPAW
                     SNSLFEDNAEFGYGMLLAQRAIRDGLKAKVEDVVANGTNEDVKAAGQEWLDTFAVGATN
                     GAATDKLVAALEACGCDKAKEILAQKDFLAKKSQWIFGGDGWAYDIGFGGVDHVLASGR
                     DINVMVFDTEVYSNTGGQSSKSTPTGAIAQFAAGGKETKKKDMASIAMSYGYVYVAQIS
                     MGADFNQTVKAIAEAEAYPGPSLIIAYAPCINHGIKKGMAKAQTEEELAVKVGYWHNFR
                     FNPAAEGNKFSLDSKAPSMEDYQAFLDGEVRYNSLKRQNPEKAARLFAKNEAEAKARFE
                     YLQKLIALHSAE"
     CDS             7149..9443
                     /locus_tag="ctg128_4"
                     /transl_table=11
                     /translation="MGTLIYIFAGWTIYAAMKHPYFSNPMIYLPLVLMGIDKIYKREKP
                     WLFIWATTVSAMSNFYFFYMICIFMFIYAAFRYFGIFSERSVKDVLGWLVKFIGYYAVA
                     LMIAAVIFLPVIMTIFGTDRFQAENYVPLLYDKIYYEKYLGDLIGENMIQWGVAGYSAV
                     AMAGVFVLFSRKKKYLDLKLGFGLLNLFLLVPFAGHVLNGFSYVSNRWIWAYGMMIAYI
                     FVKAYPELFTLTVREKKKIFVMTVAYCVLALFAKAARTQRNMAGVLVLVLAVFTVTSFG
                     NIFLQGKYMCGLLSALLVVSIMLNVSYQYSYEKDYLSEFAAEEESLDKLESNTDKAVLA
                     AGDSGVYRYDQYGALPYDNTSMYMGTNSTAYYFSLANSSISDFFSEMYLNTPWEQHYEN
                     LDGRTILDRLASVKYFVISGDNFRYLSYGYNKEKGSAGKGKSECRAYENENALPLGYTY
                     DSYIPESEYEKMDVVKKQQALMDGVVLEESTLPEASVDADNENIQYRMETGDGCALSKG
                     AIRVTKEGAQLKLVFHGLTDSENYLIADNLDYDSLSPRELIGNSQWKKMSEYDQNKVLD
                     EDSRWRYWKESKEAAMTVSSNDVTKTIKIFTDKYNAYSGRHDFLCNMGYSRSGVRTMTI
                     TFANTGVYTYDKLRVVSQPVQGIEEKTVKLGEEALENVKMGTNEITGDISVSERKALVL
                     SVPYSKGFTAYVDGKETKLQKANTMFMALELEPGSHEIRLTYCTPYLKAGMLLSVLGLV
                     IYVMLVFRKKK"
     CDS             9604..10539
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg128_5"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.3e-28,
                     bitscore: 88.8, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLSVVLPAYNEELMVGKTCRVLAEVLTEAKIPYELVVVNDGSG
                     DRTWEEIQKAGERDANVTGVLFSRNFGKEAAIFAGLAQACGDVVAVMDCDLQHPPQTLL
                     EMYRLWQEGYEVIEGVKADRGKEGFLHKECAGFFYDIMSKATKVNMKDASDFKMMDRKA
                     VDSILSMPERNMFFRATSSWVGYKTTSVEFEVQEREAGVSKWSPWALVKYAFTNIVAFT
                     TFPLQFVTITGAICFICSLVLMVYSLVQYFTGSAVEGYTTLLMVLLLVGSAMMISLGII
                     GYYISKIYEEVKRRPRYIISKVIKNGNIQD"
     CDS             10553..10969
                     /locus_tag="ctg128_6"
                     /transl_table=11
                     /translation="MKQWIRKMYESSVIRYIFFGGCTTMVNLVSFFILRKLKVELNIAN
                     IISIILAILFAYVVNSKYVFQDKCETLKDHVQPFCKFVSARLVTMVIEVGGVWLLVSVM
                     GLNDMIGKFLTQFIVLILNYVFSKFFVFTTGKSK"
     CDS             10994..12046
                     /locus_tag="ctg128_7"
                     /transl_table=11
                     /translation="MTLEEAIAKIKPLDHNAMEIAQKRWDSIAKPLHSLGKLETLLIQI
                     AGITGNAEVDLSRRGLIAMCADNGVVEEGVTQTGQEVTAIVAENFLKYDTSVGVMCKQN
                     HAEIFPVDMGMVTDTKVRTDHKIAYGTQNMTKGPAMTREQAVKGLEAGIDMVRELNDKG
                     YRILATGEMGIGNTTTSSAVASVLLKQPVEEMTGRGAGLTSEGLMRKINAIKKAIALNE
                     PDPEDAIDVLAKVGGLDIAGMAGVFLGGAVYGIPVVMDGFISCVSALIAMRICPAARDY
                     ILASHVSKEPAAHLILENMGKEAIIHADMCLGEGTGAVALFPILDLATAVYHSMSTFDD
                     IHVEQYEELK"
     CDS             12046..12588
                     /locus_tag="ctg128_8"
                     /transl_table=11
                     /translation="MLTLVTGGSGSGKSAFAEDRVLSFGDAQRIYIATMHPFDEESHKR
                     IERHQKMRAGKGFETVECYTGLKNVKLPAGCVVLLECMSNLVANEMFEEQGAHDRTVSE
                     VTKGIENLLEQAAHVVIVTNEIFSDAVVFDGDMDSYLEYLGKINQAAAQRADEVVEVVY
                     GIPVFHKSTNTCSNLCK"
     CDS             12634..13410
                     /locus_tag="ctg128_9"
                     /transl_table=11
                     /translation="MKSLWNNFKVAFAMFSKIPMPRADWTKGNMKYMFCFFPFIGTVIG
                     GLTMLVAYLGLRFGYQPGFVTAVLVLVPVFVTGGIHVDGLLDTSDALSSWQERSRRLEI
                     LKDSHAGAFAVITAAVYFIAWYGAYSQLFNSAENMRAIGILSLGFMVSRCLSGIGVITF
                     PKAKADGTVAEFSRNSSDVLSRNVLIVYLVLLAAGMILIRPVWGSLAFVGALLIFWYYH
                     HIAMKYFGGTTGDISGFFLCICEVGMALILAVVSNF"
     CDS             13421..13801
                     /locus_tag="ctg128_10"
                     /transl_table=11
                     /translation="MEMIIGGAYQGKTEYAKKQYPQLRWSDGGSVTEEELMNAQGVTGF
                     QQYIRSELENGKDVSDLAEKIICKNPDIVLVSQEVGYGVVPVDAFDRKYREAVGRVCTK
                     LAAYSHKVTRVICGIGTVIKDD"
     CDS             13794..14393
                     /locus_tag="ctg128_11"
                     /transl_table=11
                     /translation="MIKLWLIRHGKTEGNKLSRYIGTTDEPLCQEGTEFLHKMDYPKVQ
                     AVYVSPLKRCVQTAEILFPGEPVHIIEELAECDFGEFENKNYKELEGNPHYQEWIDSNG
                     TLPFPGGESREGFKSRNLRGFDRVVSGCIRSHVAEAALVIHGGTIMNIMEEYADIQKPF
                     YEWHVRNGGGYEVELDENLWKNGRKQLRVNSAIMKG"
     CDS             14701..16032
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg128_12"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.8e-39, bitscore:
                     126.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVIGNGRMITQDASNPFLENGAVAMDGNTIVMVGVTEEVKKVYP
                     DAEFVDAKGGVIMPAFINAHEHIYSSFARGLSINGYNPQGFLDILDGLWWTVDRHLTLE
                     QTKLSAYATYIDSIKNGVTTVFDHHASFGHITGSLNAIEEAAKDLGVRTCLCYEISDRD
                     GMEKSRESVMENVNFIKHALADDSDMIAGMMGMHASFTISDETMALCNELKPEGVGYHI
                     HVAEGIYDLHQCLKEHGKRIVDRLHDWNILGPKTLLGHCIYVNEHEMDLIKDTDTMVVH
                     NPESNMGNACGCPPTMRMVQKGILTGLGTDGYTHDMMESWKVANVLHKHSLCDPNAAWG
                     EVPQMLFEGNAKIANRYFKKQLGVLKEGAAADVIVIDYDPLTPMNESNINGHLMFGVNG
                     SMVQTTVCNGKVLMKDREVLVCDEAKVMADCRQAAKELADDING"
ORIGIN
        1 ccgtaccctg ttattttatt ctttagttat cggaagcgtc ctcttcgttg atctcgaata
       61 cgtgacgttt cttagccatc tcatcacttg ccagatattc atcgtaagta gtgatcttgt
      121 cgatcatggt tccgtttgga aggatttcca tgatacggtt ggctgttgtc tgtacgaact
      181 gatggtcatg tgaggtgaaa aggataacac ccgggaattt gatcagaccg ttgttcagtg
      241 ctgtgatgct ctccatgtcg aggtggttgg ttggctcatc aaggatgaga atgtttgcac
      301 cggagatcat catcttggaa agaagacagc gaaccttctc accaccggaa agaacacgta
      361 cacgtttgat gccgtcttca ccggggaaga gcatacgtcc gaggaagcca cgaacataag
      421 tagcatcctt gatctcagag tactgtgtca gccagtctgt aatggtaagg tcattatcga
      481 actctgcagt gttgtcctta gggaaatatg cctgagaagt ggtaacaccc catttataat
      541 ttccttcatc cggttccatt tcaccgacca ggatcttaaa cagagtagtg attgcctgtt
      601 cgttagcacc aacaaaagct actttgtcat catgaccgag tgtgaaagaa atgttatcca
      661 gaactttcac accgtcgatg gtcttggaaa ggttctccac cataaggact tcgttaccga
      721 tctcgcggtt tggacggaaa tcgatatatg ggtatttacg gctggacgga cgcatatcgt
      781 caagctggat cttttccagg gcacgcttac gggaagtcgc ctgtttggac ttggaagcgt
      841 tggcactgaa tcgggaaata aactcctgaa gttctttgat cttttcttct ttcttcttgt
      901 tggcttcctt catctgtttg atgaggagct ggctggactc aaaccagaag tcatagtttc
      961 cggcatagag ctgaatcttg ccgtagtcga tgtctgctgt atgagtacat actttattta
     1021 agaagtaacg gtcatgggat acaacgatga cagtgttgtc aaagttgatc aggaattctt
     1081 cgagccattc aatagcaggc aggtcaaggt ggttggtagg ctcatccaga agaagaatgt
     1141 ccggattacc aaacagtgcc tgcgccagaa gaactttgac cttctggctt cctgtaaggt
     1201 cagccatctg ggaatagtgg agatcggttt caattccaag accattcaga agagtagcag
     1261 catcagattc tgcttcccat ccgttcatct ctgcaaattc accttccagt tcactggcac
     1321 ggataccgtc ttcatcagtg aagtccgctt ttgcatagat agcatctttt tctttcatga
     1381 tctcatacag tctcttgtta cccatgataa cagtatccag aactgtatat gcatcatatt
     1441 tgaagtgatc ctgctgcagg aaagagagac gctggccggg agtgataaca acgtcaccgt
     1501 tggtaggctc taactgtccg gaaaggattt taaggaatgt ggacttaccg gcaccgtttg
     1561 caccgatgag accgtagcag ttgccctcag taaatttgat atttacatct tcgaagaggg
     1621 cctttttacc tacgcgcaat gtaatattgt ttgctgaaat catatcatac ctctttttcg
     1681 tgaaattatt gttttgcagt aactgtccgg cagattgttt atggaaaacg tatctttcgc
     1741 aggaaacagt tacattattt cctattatat aagttacaac cgcttatcat tgtaccgtaa
     1801 attgggaaat ttgcaactgt tttttgcttt tttgggttct tttatttaca aaaaaaagaa
     1861 gcactgttat aatataaaat aaatatagcc tcttgacaga cagaaatatg aggcattgat
     1921 atgacagaaa taacgattac tgtttccatt gttttatgca aaacagcgat gtggacagta
     1981 aaggataatt aattttagag aggttgcaaa gactatgttt attacaagag agtgcgatta
     2041 tgcagttcga gtggtacgtg cgctttgggg agagagcaga ctgagcgtat ccgatatctg
     2101 tgagaaagaa gcaatcacag ctccttttgc ctataagatt ctgaagaaac ttcagaaggc
     2161 agagatcgtg aagggataca gaggcgtaca tggtggttat tctctgaaca ggggactgga
     2221 tgagttgact ttatatgagg tttattcagc gattgatccg gatatgttta tcatcgaatg
     2281 tctggatccg aaatataact gtgtcagaga cggacaggat ggattgccat gtctggtaca
     2341 tagagaattg ttatctgtac aggatgaact gataagtctc cttaagagaa aaacaataca
     2401 gcagatcatg gaggaggcgt agagcctcct ttttttactt ttatctgcct gattcgtccg
     2461 aaatttggca tatctgcata atgttagtta tatgcaactc aaaaaatgca catatttgct
     2521 actgaaataa cagaaaatct ctgctttgta cctcagaaga tacaaaatat gtcaaaacaa
     2581 attggacaca ggcagaagat tatgttataa tctacaatga aatttgaggt atattttact
     2641 tatgccttga aataaataat taattttcat caacctttaa ggaggaaaaa caaactatgg
     2701 caagaaagat gaaaaccatg gatggtaacc atgcagctgc tcatgcttca tatgcatact
     2761 cagatgtagc cgctatttac ccgatcactc cttcatctgt tatggcggaa gcaacagatg
     2821 aatgggcaac ccagggaaga aagaacattt tcggacagga agttcaggta actgaaatgc
     2881 agtctgaggc tggtgcagca ggtgctgtac acggatctct ggcagcaggt gctttaacaa
     2941 caacatatac agcatctcag ggtctgttac ttatgatccc gaacctttac aaaattgccg
     3001 gtgagcagtt acctgcagta ttcaacgtat ctgcacgtgc acttgcttcc cacgcacttt
     3061 caatcttcgg tgatcactcc gacgttatgg cctgtcgtca gaccggatgc gcaatgctct
     3121 gcgaatcttc tgtacaggaa gttatggact taacacctgt tgctcacctt gcagcaatca
     3181 aaggtaaagt tccgttcatc aacttcttcg acggattccg tacatctcac gagatccaga
     3241 agatcgagac atgggattat gaagatctta aggatatggc agatctggaa gcaatcgctg
     3301 aattccgtaa ccatgccctg aatccgaatc acccatgcca gagaggttcc gctcagaacc
     3361 ctgatatctt cttccaggca agagaagcat gtaacccata ctacgatgct cttccggcag
     3421 tggttcagga atacatggac aaagttaacg ctaagatcgg tacagattac aaattattca
     3481 actactacgg agctgctgat gcagaacacg taatcgttgc tatgggttct gtaaacgata
     3541 caatcgagga gacaatcgac taccttgcag cagcaggaaa gaaagtcggt gttgttaaag
     3601 ttcgtcttta cagaccattc tgcgcacagg cactcatcga tgcaattccg gaatctgtaa
     3661 aacagatcac agttcttgac agaactaaag agccaggtgc acttggcgag ccactgtacc
     3721 ttgacgttgt agcagcatta aaagacagca aattcggcgg cgtaaaagta ttctccggac
     3781 gttatggttt aggttccaaa gatactacac ctgcacagat tgtagctgtt tatgagaaca
     3841 ctgctaaaga aaaattcaca atcggtatcg ttgatgatgt tactaacctt tcccttgaga
     3901 caggtgctcc gatcgtaaca actcctgaag gaacaacaaa ctgtaaattc tggggtctgg
     3961 gagctgatgg tacagtaggt gccaacaaga actccatcaa gatcatcggt gacaacacag
     4021 acatgtacgc acaggcttac tttgattatg actccaagaa gtccggtggt gttacaatgt
     4081 cccacttacg tttcggtaag aaaccgatca aatccacata cctgatccac aaagcaaact
     4141 tcgtagcatg tcataatcca tcctacgtaa acaaatacaa catggttcag gaacttgttg
     4201 acggtggtac attcctcctt aactgtgcat gggatatgga aggtcttgag aaacatttac
     4261 caggacaggt aaaagctttc atcgctaacc acaatatcaa attctacaca atcgacggtg
     4321 ttaagattgg tattgaaact ggcatgggac caacacgtat caacacaatc cttcagtctg
     4381 cattcttcaa acttacagga atcattccgg aagagcaggc aatcgacctt atgaaagctg
     4441 ctgctaaggc aacatacgga cgtaagggtg atgatgtggt acagaagaac tgggcagcta
     4501 tcgatgccgg tgctaaacag gttgttgaga tccaggttcc ggaaagctgg aagaacgctg
     4561 aggacgaagg tcttcatatg actcatgcaa cagaaggacg tcaggatgtt atcgatttcg
     4621 ttaacaatat ccaggctaaa gttaatgctc aggaaggtaa ctccttacct gtatctgcat
     4681 tcaaggatta tgtagatggt acaacaccat ccggttctgc tgcatatgaa aaacgtggta
     4741 tcgcagttaa cgttcctgta tggaatccgg aaaactgtat ccagtgtaac agatgtgctt
     4801 atgtctgccc gcacgcagtt atccgtcctg tagctctgac agctgaagaa gcagctaatg
     4861 ctcctgaagg catgaagaca ttagacctta caggtatgaa agaatataaa ttcacaatgt
     4921 ccgtatccgc acttgactgt acaggatgtg gttcttgtgt aaacgtttgc ccaggtaaga
     4981 agggtgcgaa agcacttgct atggaaaacc ttgaagcaag cgcagacgag cagaaatact
     5041 ttgactacac agttaaactg ccggttaaag aagatgttat cgctaaattt aaagaagcaa
     5101 ctgttaaagg cagccagttc aaacagcctc tgcttgagtt ctctggagct tgtgcaggat
     5161 gtggtgaaac accatacgct aaactgatca ctcagctgtt cggtgacaga atgtacatcg
     5221 caaacgcaac aggatgttct tctatctggg gtaactcctc accatctaca ccatacacag
     5281 taaacgctaa gggacagggt cctgcatggt ccaactctct gttcgaagat aacgctgagt
     5341 ttggttatgg tatgcttctt gctcagagag ctatccgcga tggcttaaaa gcaaaagttg
     5401 aagacgttgt tgctaacgga acaaacgaag acgttaaggc agctggtcag gaatggctgg
     5461 atacatttgc tgtaggtgct acaaacggcg ctgctacaga caaacttgtt gctgctcttg
     5521 aagcttgcgg atgtgacaaa gcaaaagaaa tccttgctca gaaagatttc ctggctaaga
     5581 aatcccagtg gatcttcggt ggtgacggat gggcttacga tatcggattc ggtggtgttg
     5641 accatgttct cgctagtgga cgtgacatca acgttatggt attcgataca gaggtttatt
     5701 ctaatacagg tggacagtct tccaagtcta cacctacagg tgctatcgct cagttcgctg
     5761 caggcggtaa agagactaag aagaaagata tggcttccat cgctatgagc tatggctatg
     5821 tatacgttgc tcagatttcc atgggtgctg acttcaacca gactgtaaaa gctattgcag
     5881 aggctgaggc ttatccggga ccatctctga tcatcgctta tgctccatgt atcaaccatg
     5941 gtattaagaa aggtatggca aaagctcaga cagaggaaga attagcagtt aaggttggat
     6001 actggcataa cttcagattc aatcctgcag ctgaaggaaa caagttctct cttgattcca
     6061 aggctccgag catggaagat tatcaggcat tccttgacgg tgaggttcgt tacaactctc
     6121 tgaaacgtca gaatcctgag aaggctgcaa gactgtttgc taagaatgag gctgaggcta
     6181 aggctagatt tgaatatctg cagaagctga tcgctcttca tagtgctgaa taatcttttc
     6241 ggtttttgaa cgattgataa ataatattat aaaataaaca gattgagctg tttattgtgt
     6301 ccggacgata tatgtgggcc gcggtacttt tgtatcgcgg ctctttttat aagggacgtc
     6361 aagaaatgaa ataacttctg gggctcagtc tcggaaccac tgaatttcta agcatttgaa
     6421 aagccactaa aagcattcaa aaatagctca aactcgcctg cggctcagac agtgagcgat
     6481 ttctgaataa cgcggctttc caaatactaa gaaattcaat gaaccctcaa aattcgcccc
     6541 agaagttatt tcatttcctg actggatgct ggctgattta aatactttcg ttgtttttaa
     6601 acaataaaat aatgttgacc ataaatttga caagtattgg atatttgtct ataatcagtg
     6661 agaactttat aactcggttt agaatgatag aatataaagg agcggttatg aggagatttg
     6721 cgagtaagga tagtaagagg gatttctata tattatatac gctggttttt ggggttattg
     6781 cggggtttat ttattatcag tttgcaggga atgggaagtc tttggtgtgg agtcatgacg
     6841 ggattccgca gcatttgaat tctctggcgt attatgggcg gtatctgagg gaggttctgc
     6901 atacgatttt tgtagagcat aagctggaat tgcctatgtg ggatatgaat atcgggtatg
     6961 gttcggatat tcttacaact ttgcattatt atgtgatcgg ggatccgctg actttgttgt
     7021 ctgtgtttgt gccggcggat aagacggagg ttttgtatga ggttctgatt tttctgagga
     7081 tttatctggc ggggatttct tttagtgttt tttgttttta tcataagaat ccgaagcagg
     7141 cgacgtttat gggaacgttg atctatattt ttgcgggatg gacgatttat gcggctatga
     7201 agcatccgta tttttccaat cctatgattt atctgccgct ggttctgatg gggattgata
     7261 agatttataa gagggagaag ccatggctgt ttatctgggc gactacggtt tcggctatgt
     7321 cgaatttcta tttcttttat atgatctgta tttttatgtt tatttatgcg gctttccggt
     7381 attttgggat tttcagtgag agaagtgtga aggatgttct gggatggctg gtgaagttta
     7441 tcggctatta tgcggtggct ttgatgatcg cggcggttat ttttcttccg gtgatcatga
     7501 cgatttttgg tacggacagg tttcaggctg agaattatgt gcctctttta tatgataaaa
     7561 tttattatga gaagtatctg ggtgatctga tcggagagaa tatgatccag tggggggttg
     7621 ccgggtattc tgctgttgct atggcgggtg tgtttgtgct tttctccagg aagaagaagt
     7681 atctggatct gaaattagga tttgggctgt tgaatctgtt tttgctggtg ccttttgcag
     7741 ggcatgtgct caatggtttc tcttatgtgt ccaacaggtg gatctgggct tatgggatga
     7801 tgatcgcgta tatttttgtg aaggcgtatc ctgagctgtt tactctgact gtgagggaaa
     7861 agaagaagat ttttgtcatg acggtggcgt attgtgtgct ggctctgttt gcgaaagctg
     7921 ccagaacgca gagaaatatg gcaggtgtgc tggttctggt attggctgtg tttacggtta
     7981 cctcttttgg aaatattttt ctgcagggga agtatatgtg cgggcttctc agtgctttgc
     8041 ttgtggtgag cattatgttg aatgtttctt atcagtattc ttatgagaag gattatctgt
     8101 cagagtttgc agccgaagag gagtcgctgg ataagctgga gtcgaatacg gataaggcgg
     8161 ttcttgctgc cggggattca ggtgtctatc gttatgacca gtatggggca ttgccctatg
     8221 ataatacttc tatgtatatg ggtacgaaca gtactgctta ttatttcagt cttgcaaaca
     8281 gcagtatcag tgattttttc agtgaaatgt atctgaatac gccatgggag cagcattatg
     8341 agaacctgga cggaaggacg attctggaca ggctggcttc tgtgaaatat tttgtgataa
     8401 gtggtgataa tttccgctat ctttcctatg gatataataa agagaagggc tctgcaggaa
     8461 agggaaaaag tgagtgcagg gcttatgaga atgagaatgc actgcctctg ggttatactt
     8521 atgacagtta tattcctgaa tcggaatatg agaaaatgga tgtggtaaaa aagcagcagg
     8581 ctttgatgga cggtgtggtg cttgaggaga gtacactgcc tgaggcatct gttgatgctg
     8641 ataatgagaa tatccagtat cgtatggaga caggggatgg ttgtgctctg tctaagggag
     8701 caatcagggt gacgaaggaa ggggcgcagc tgaagcttgt gttccatggt cttacggaca
     8761 gtgagaatta cctgatcgca gataatctgg attatgacag tctttcaccg agagaactga
     8821 ttggtaacag tcagtggaag aagatgtctg agtatgacca aaataaggtt cttgatgagg
     8881 acagccggtg gcgatactgg aaggaatcaa aggaagcggc tatgacagtc agctccaatg
     8941 atgtgaccaa gaccataaag atttttacgg ataagtataa tgcctacagt ggacggcatg
     9001 attttctctg caatatggga tattccagat caggagttcg tactatgacg atcacctttg
     9061 ccaatacggg tgtttatacc tatgataaat taagggttgt gagtcagccg gtgcagggga
     9121 ttgaggaaaa aactgtgaag ctgggtgaag aagctctcga gaatgtaaaa atgggaacga
     9181 atgagattac aggtgatatc agtgtttccg aaaggaaagc tcttgtgttg tctgttccgt
     9241 acagtaaggg atttacggct tatgtggacg ggaaagaaac gaagcttcag aaggcgaata
     9301 ccatgtttat ggctctggaa ctggagcctg gttcacatga gatacgcctg acatattgta
     9361 cgccttatct gaaagcggga atgcttcttt ctgttctggg gctggttata tatgtaatgc
     9421 tggtgttcag gaagaaaaag taatccaaat tccattgttg caggcagcct gaaataaatt
     9481 tgttagaata gacatttttg taaatttgtg tataataaaa tagaaaatat ttacaggaat
     9541 aacagacagt gaatgagaaa ttggtctgtt gtaaatgaat gaaataaaat gaggaatgac
     9601 atcatgagta aattatcagt ggtacttccg gcatataatg aggagctgat ggttgggaaa
     9661 acctgtcggg tgctggcgga agttcttaca gaagcgaaga ttccctatga gctggtggtt
     9721 gtaaacgatg gttccggcga ccggacatgg gaagaaattc agaaggcagg agagagggat
     9781 gcgaatgtga caggcgttct tttttccaga aatttcggaa aggaagcagc gatttttgca
     9841 ggactggcac aggcctgtgg agatgtggtg gctgtcatgg actgtgacct gcagcatccg
     9901 ccgcagacac ttcttgagat gtacaggctg tggcaggaag gctatgaagt gatcgagggc
     9961 gtgaaggcag acagaggaaa agagggcttt ttacataaag aatgtgcagg atttttctat
    10021 gatatcatgt ctaaggcaac taaggtgaat atgaaggatg cctcggattt taagatgatg
    10081 gacaggaaag ctgtggacag tattctgtct atgcctgaga ggaatatgtt ctttcgggct
    10141 acctcttcct gggtgggata taagactacc agtgtggaat ttgaggtgca ggagagagag
    10201 gccggcgttt ccaagtggtc tccctgggcg ctggtgaaat atgcgttcac aaatatagtg
    10261 gcatttacta cttttccgct gcagtttgtt acaatcacag gagcgatatg ttttatctgt
    10321 tcgctggtac ttatggtcta ttcgcttgtg cagtatttta caggttctgc agtggaaggt
    10381 tataccaccc tgctgatggt gctgcttctg gtgggaagcg ccatgatgat cagtcttggg
    10441 atcattggat attatatttc caagatttat gaagaagtaa agcgcagacc gagatatatt
    10501 atttcaaaag taattaagaa tggaaatata caggactgag aggatatatt ttatgaagca
    10561 atggatcaga aaaatgtatg aaagttccgt tatccgctat attttctttg gcggatgtac
    10621 cactatggta aatctggtca gctttttcat tctcagaaag ctgaaggtgg agctgaatat
    10681 cgccaatatt atttcaatca tcctggcgat cctgtttgcc tatgtggtaa attcgaagta
    10741 tgtttttcag gataaatgcg agacattgaa ggatcatgtt cagccattct gcaaatttgt
    10801 cagtgccaga ctggtcacta tggtgatcga ggttggcggt gtatggctgc ttgtgtcagt
    10861 gatggggctt aatgatatga tcgggaaatt cctgacacag tttattgtgt tgatactgaa
    10921 ttatgtattc agtaaatttt ttgtgtttac aacagggaaa tcaaaataat gaaggaaaag
    10981 agagggaaaa ctcatgactc tggaagaagc tattgcaaag attaagccat tagatcacaa
    11041 tgccatggag attgcacaga aaagatggga cagtattgca aaaccactgc attctcttgg
    11101 aaaactggag actcttttga tccagatcgc gggaattaca ggaaacgcag aggtggatct
    11161 ttccaggaga ggtctgatcg ccatgtgcgc ggataatggc gtggtagaag agggtgtgac
    11221 acagaccgga caggaagtta ctgccatcgt tgccgagaat tttctgaaat atgacacatc
    11281 tgtcggtgtg atgtgtaagc agaaccatgc ggagattttt ccggtggata tggggatggt
    11341 gacggacaca aaagtccgca cagaccataa aattgcctat ggtacacaga atatgaccaa
    11401 gggtcctgcc atgacaagag aacaggctgt aaaggggctt gaagcaggca ttgacatggt
    11461 aagggaactg aatgataagg gctaccggat tctggcaaca ggggaaatgg gaatcggaaa
    11521 tacaaccacc agcagtgcag ttgcttctgt gttgctgaaa cagccggtgg aagagatgac
    11581 agggcgcggc gcaggtctga ccagcgaggg acttatgcgc aagatcaatg cgatcaaaaa
    11641 agccattgca ttaaatgaac cagatcctga ggatgctatt gatgttctgg caaaggtagg
    11701 cggtcttgat atcgctggaa tggcaggtgt ctttctggga ggtgcggttt atggtattcc
    11761 tgtagtcatg gacggattta tttcctgtgt ttctgcgctg atcgccatgc gtatctgccc
    11821 ggctgcgagg gattatattc ttgcatccca tgtatcaaaa gagcctgctg cccatctgat
    11881 ccttgagaat atggggaaag aggcaatcat tcatgcggat atgtgtctgg gcgagggaac
    11941 cggagcagta gctttattcc cgatccttga tctggcaaca gctgtttatc attctatgag
    12001 tacttttgat gatatccatg tggaacagta tgaggagttg aaataatgct gacgcttgtg
    12061 acagggggga gcgggagcgg aaaatccgct tttgcggaag acagggtgct ttctttcgga
    12121 gatgcacaga ggatttacat agcgaccatg cacccttttg atgaagagag ccataaaagg
    12181 atcgagagac accaaaagat gcgtgcagga aaaggtttcg agacagttga gtgctataca
    12241 gggctcaaaa atgtgaaact gcctgccgga tgtgtggtgc ttctggaatg catgtcgaat
    12301 ctggtggcaa atgaaatgtt tgaagagcag ggagcccatg accggacagt ttcggaagtt
    12361 acaaaaggga ttgagaatct gctggaacag gctgctcatg tggtgatcgt tacaaatgag
    12421 attttttcag atgcggttgt gtttgatgga gatatggatt cttatctgga atatctggga
    12481 aaaatcaatc aggctgctgc gcagagagct gatgaagtgg tggaagttgt atatgggata
    12541 ccagtctttc acaaatccac aaatacctgc agcaatcttt gcaaataata tatttgacag
    12601 gattgccata atatgaaaaa gaggaattga tcaatgaaat ctttatggaa taattttaag
    12661 gtggcatttg ccatgttttc taagattccc atgccccgcg ctgactggac aaagggaaat
    12721 atgaagtata tgttctgttt ttttccgttt atcggaactg tgatcggcgg gctgactatg
    12781 ctggtggcgt atctgggact tcggtttggg tatcagccgg gattcgtgac agcagtgctg
    12841 gtgctggtac ctgtatttgt gacaggcggg atccatgtgg atggtctttt ggatacttcg
    12901 gatgccctga gttcctggca ggagagaagc agaaggctgg agattcttaa ggattcccat
    12961 gcaggtgctt ttgccgttat tactgcggcg gtatatttca ttgcctggta cggcgcttac
    13021 agtcagttgt ttaacagtgc agagaatatg agggcgatcg gaattctgag ccttggcttt
    13081 atggtttcca gatgtctgtc agggatcgga gttattacct ttccgaaagc aaaggcagac
    13141 ggtacagttg ctgagttttc cagaaattct tcagatgtgc tctcgagaaa tgtgctgatc
    13201 gtctatctgg tgcttctggc tgcgggaatg atcttgatcc ggcctgtatg gggaagtctg
    13261 gcttttgtgg gagctttgct gattttctgg tattatcatc atattgcgat gaagtacttt
    13321 ggcgggacaa ccggggatat ttcgggattt tttctttgta tctgtgaagt tgggatggca
    13381 ttgatcctgg cggtggtttc taatttttga ggagaagagt atggaaatga taatcggcgg
    13441 tgcatatcag ggaaagactg aatatgccaa gaaacagtat ccacagttaa ggtggagtga
    13501 cggcggttct gtcacagagg aggaactgat gaatgctcag ggtgtgactg gttttcagca
    13561 gtatatccgc agtgaactgg agaatggaaa agatgtgtca gatcttgcgg aaaaaatcat
    13621 ctgtaagaat ccggatattg tccttgtctc tcaggaagta gggtacgggg ttgtacctgt
    13681 ggatgctttt gacagaaaat acagagaggc tgtagggcgt gtatgtacga agctggcagc
    13741 atacagccat aaagtgacgc gcgtgatctg cgggatcgga acggtgatca aagatgatta
    13801 agttatggct gatcagacat ggaaaaacag aagggaataa actttccaga tatatcggca
    13861 caacggatga gccgttatgt caggagggaa cagagtttct gcataagatg gattatccaa
    13921 aggttcaggc ggtttatgta agtcctctga aacgatgcgt gcagacagca gagattcttt
    13981 ttccgggaga gccggtacat attattgaag agctggcaga atgtgatttc ggagagtttg
    14041 aaaataagaa ctataaagag ctggaaggta atccgcacta tcaggaatgg attgacagca
    14101 acggtactct gccttttccg ggaggagaaa gcagggaagg gtttaaaagc agaaacctga
    14161 gaggatttga cagggttgtg tccggatgta tccgcagcca tgtggcagag gcggcacttg
    14221 tcatccatgg cggtacgatc atgaatatca tggaagagta tgcagatata cagaaaccat
    14281 tttatgagtg gcatgtgaga aatggcggcg gctatgaggt ggagctggat gagaatctct
    14341 ggaagaatgg acgaaaacag ctcagggtta attctgcgat tatgaaagga taactctcct
    14401 atcttacaaa aattgttgac aaacctgaaa atttgtcata aaatcagctt catcagaaaa
    14461 caggaaaatc aaaaaaagaa cgaggttgtt cattgtcatc aatgactgcc ccgttctttt
    14521 tttatctgtt caccggagat agtataaaac ctaaaaaaaa tttgaaaaac caaaaagttt
    14581 ttgtgaattc tacttgcatt attcggagaa gtatgttaca gtattagtac ataattccta
    14641 aacgaaaggt aaaaagcagt atcgaattgg tagtttttga caagtgaaag gaggaactat
    14701 atgctggtaa ttggtaatgg aagaatgatc acacaggacg catccaaccc attcctggag
    14761 aatggtgctg tagcaatgga tggtaacacc atagtaatgg tgggggtaac tgaagaggta
    14821 aagaaagttt atccggatgc tgaatttgtt gatgcgaagg gtggggttat catgccggca
    14881 tttattaatg cccatgagca tatctacagc tccttcgcaa gaggcttaag cattaacgga
    14941 tataatcctc agggatttct ggatattctg gatggcttat ggtggacagt tgaccgtcat
    15001 ctgacactgg agcagacaaa gctttctgca tatgctacat acattgattc tatcaagaat
    15061 ggtgtaacca cagtgtttga ccaccatgca agctttggcc atattacagg ttccctcaat
    15121 gcgatcgagg aagctgcgaa ggatttaggt gtgcgtacct gcctctgcta tgagatttct
    15181 gaccgtgacg gaatggagaa atccagagaa tctgtaatgg agaacgtgaa ttttatcaag
    15241 catgcacttg cagacgacag tgatatgatc gccggaatga tgggtatgca tgcatccttt
    15301 acaatctctg atgagacaat ggctctctgc aatgaactaa aaccggaagg tgttggatat
    15361 cacatccatg tagcagaagg catttacgat ctccatcagt gtctgaaaga gcatggcaaa
    15421 cgtattgttg accgtcttca tgactggaac atccttggac cgaagacttt gctcggtcac
    15481 tgtatctatg tgaatgaaca tgagatggat ctgatcaaag atacagatac catggttgta
    15541 cataacccgg aatctaacat gggtaatgca tgcggatgtc ctccaactat gagaatggta
    15601 cagaagggaa tcctcacagg tcttggtaca gacggatata ctcatgatat gatggaatcc
    15661 tggaaggttg caaatgtttt acacaaacac agcctctgcg acccgaacgc agcctgggga
    15721 gaagttccac agatgctttt tgaaggaaat gcaaagattg caaacagata ctttaagaaa
    15781 cagctcggtg tcctgaaaga gggtgcggca gcagacgtga tcgtgatcga ttatgatccg
    15841 ctgacaccaa tgaatgaaag caacattaac ggacatctga tgttcggtgt aaacggaagc
    15901 atggtccaga ctactgtatg taacggtaaa gtcctgatga aagaccgcga agtccttgta
    15961 tgcgacgagg caaaagttat ggcagattgc cgtcaggctg caaaagaact tgcagatgat
    16021 attaatggtt aatctgtaaa gaattgtaaa aaagataagt tttctgcctg gcaaaaataa
    16081 atgtaaataa aatatagaac ggatggagag aagccatacc gtatgaaata atggaggatc
    16141 ggattatgag tgaagtcatg acctgtatgc cctttgaaca gttaatgaac tgggtattag
    16201 aagaaaagaa aacaaaagga acagttttcg gac
//
