LOCUS       c00186_gnlPro..        14186 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FMKPLICD_192.
ACCESSION   c00186_gnlPro..
VERSION     c00186_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:36:25
            Original ID  :: gnl|Prokka|FMKPLICD_192
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14186
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14186
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5259:7511]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5260..7511
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14186
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14186
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..146
                     /locus_tag="ctg186_1"
                     /transl_table=11
                     /translation="RRELLKPLPATERSLLEAKVPPVKRRTSCVYADLRELHLQMEILK
                     VA"
     CDS             836..1273
                     /locus_tag="ctg186_2"
                     /transl_table=11
                     /translation="VATKVDKKNAIRQGITEAEIVYFQNLAGKTFLYVCGDEYFEVSFP
                     IDHFLHLTGVETRLSTKDFYKNAKKSILTNNQFYFDARHVYANAKRKLPCLKRLPELTN
                     EMVCVLKNMETMTITYKLSVTNLEFTGSVTRKPKRYTGKKD"
     CDS             1405..1764
                     /locus_tag="ctg186_3"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             1824..4178
                     /locus_tag="ctg186_4"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTITVNV
                     TQTAADTIASQIETIVYSHEPDVEVQEETVMNVTKSYSLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAQTAADTIASQIETIVHSHEPDVEVSEIVQESYIPEKKQEA
                     NESYNNEDKKLTVRLATGAAIYAIGMALTVFAKVPLPIELAFLIVSYVILGGDVVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVKRSRKSISDL
                     MDIRPDSATVRRNGELITISPENVSIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLMIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAFLAILPPIILGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSVIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAA
                     EAESFSNHPIAKSILAAYGKEMDQSVIFDYKEISGYGISVMAGEKKVFAGNTKLMDTEC
                     IEYTTCEKAGTKVYLAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKSVAEELQLDEYYAQLLPDQKVEKVELLDSKKRPGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIDVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             4195..4713
                     /locus_tag="ctg186_5"
                     /transl_table=11
                     /translation="VKRKLILLAVTIVFLAGFGALLHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLVSYAKKLCDRLKQAGFSVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLTQMDY
                     MIMDSEEMR"
     CDS             4724..5263
                     /locus_tag="ctg186_6"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNVIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             5260..6804
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 269.9; E-value:
                     1.4e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg186_7"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.8e-83, bitscore:
                     269.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.7e-17,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANGEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSACEQ
                     ADVVDLSCATQIDFPPASQISEIKQLNKVMQETMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             6810..7511
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 90.3; E-value: 2.6e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg186_8"
                     /sec_met_domain="Fer2_3 (E-value: 7.2e-29, bitscore: 90.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00072, bitscore: 10.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKADSYWQEFEYDGSKNSSVATVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTIILEPLSKFPL
                     VRDLIVDRSNLFENLKKLNLWLESEAYMSSWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGTVAAVNAFRILNEEQESTHLNEISAEYKKRFFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAVVWGK"
     CDS             7536..8279
                     /locus_tag="ctg186_9"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLAAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFFLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             8272..8685
                     /locus_tag="ctg186_10"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             9357..9884
                     /locus_tag="ctg186_11"
                     /transl_table=11
                     /translation="MKYEYMKESEQMLQYFQFPKFLLKLRISQTAKFLYMILYDRARIS
                     RKNSWIDKYGNVYLIFPIDELSVQIDKCKSSVKTALKELDDVGLLVRRSGGFSKPNHLY
                     VKIPSDEIGLQPVDNKAVEKIVATEPEKPPSSGRKNGCGGVGNVAPSKVTEKYKSNKYH
                     EVNYCYGEGESL"
     CDS             9884..10699
                     /locus_tag="ctg186_12"
                     /transl_table=11
                     /translation="MREEDTVCVGSDGLKYCKVCGEAKEAFFPKDRFMGMKKHSRQCAC
                     DRKAYEEEQKYFKDKEHRELVSRNTSICFDESRMEEWTFENADMSDTVMHRAKKYVDNW
                     EEMKRNHIGCLFWGPVGTGKSFIAGCIANELLKQEVMVKMTNFNTIIDDIFPLADKTEY
                     INALASYQLLIIDDLGVERNSEYALGIIFSVIDRRIRSGRPLIITTNLPLKEIKNETML
                     DKRRIYDRILEMCTPMYVGGTSKREVIASMKMEKAKTLLNTNRGEEDCE"
     CDS             10696..10905
                     /locus_tag="ctg186_13"
                     /transl_table=11
                     /translation="MNHTEKTIPVWEKYSLNVSEAAEYYGIGEKRLRQIAGENEGADFI
                     LEVGSHIRFKRKLFEDYLDTASTV"
     CDS             11041..12240
                     /locus_tag="ctg186_14"
                     /transl_table=11
                     /translation="MSEKRRDHRGRILHNGEIQLSDGRYRFKYVDEMGKERCVYSWRLD
                     HNDATPKGKRRTLSLREMEKKIQADHFEQIATNGGNMTVLELVEKYTSTKTGVRPTTVA
                     GYGTVINLLKKDPFGKRRIDTVRISDAKCWLIHLQQVEKKSYSSIHSIRGVLRPAFQLA
                     VDDDLIRKNSFQFQLMEVVVNDSVTREAISRAEERKFLRFVKEDPHFCRYYEGIYILFK
                     TGLRISEFCGLTISDIDFKEHTINIDHQLQKKSKIGYYIQETKTTSGTRKIPMTADVEE
                     CFRKIIEKRNPPKAEPMVDGKSGFLYFDKNESICYSLHWEHYFQHIIQKYNNTYKVQMP
                     VITPHVCRHTYCSNMAKSGMNPKALQYLMGHSDISVTLNTYTHVNLEDAREEVARIQVV
                     "
     CDS             12607..12990
                     /locus_tag="ctg186_15"
                     /transl_table=11
                     /translation="MSGLKKHIYEEKNGLHYTLNGDYYLPDLKLPEEHRPIGKYGRMHR
                     EYLREVHPARLNTLTLTGELWTYLADLNEQAQKRLDTIIEQMKAAEGVTEELKSICQME
                     WVQRCNNIHNRAEEIVLHEMIYS"
     CDS             13506..14156
                     /locus_tag="ctg186_16"
                     /transl_table=11
                     /translation="METKLERIAEISANSPGPEFTSLYHLINKEMLLQCHKELDGNKAV
                     GVDEITKKEYGRNLEQNLDDLVERLKRKSYKPQPSIRVYIPKSNGKLRPLGIACYEDKI
                     VQLALKKILEAIYEPRFLNCMYGFRPNRGCHNAIKELCKRLNNTKICYIVDTDIKGFFD
                     HMKHEWIIKFLKLYIKDPNIIGLVKKYLKVGVLDNGELMANEEGSAQGGLCKA"
     CDS             14098..14184
                     /locus_tag="ctg186_17"
                     /transl_table=11
                     /translation="MVNLWRMKKVQLKVDYAKLSIDFPMQSSR"
ORIGIN
        1 ttagacggga acttttaaaa ccccttccgg caacggaaag gtctttactg gaggcaaaag
       61 tccctcctgt aaagcgtaga acctcatgtg tttatgctga cttaagagaa cttcatctgc
      121 aaatggagat cttaaaagta gcataaacac aggcagatat acagcggact acctgtaatg
      181 tggaaacctg ccgtatccgg catggaaaaa gcgcataatt gtgcagacct aagttacagg
      241 cgtatccgcc gatattcagt ctgacgccta aagcgtctgg aagcacgtga ctttagccat
      301 gtgaggttca cgattatcgg aaaatgcctg taaacagcgt aaatacagca tttcaaggag
      361 ttttaagcaa tgataagagt gttatttgtc tgccacggca atgtttaatg gatgccgtga
      421 aagccttgat tttattggat ttcttgggaa ttaaccaata atttacacct tatttatacc
      481 tttggaagac cggatcggaa taatataata aaatttgcta atctgtgttg atttttttta
      541 tgattgagta taataaaatc aagaacagaa atgttctcga tgtaagagca tcgttaaaag
      601 ttgggctgca gatggagcag ggtaaacttc catctcatta gatgtcttaa ctgggcatcg
      661 agcctggtag cttggataaa gctgtagtcc acgtggggga cttaatgatt ttcacgtcgt
      721 tatgggtatc ttaactgggt atcgaggctg acaaccagca gaaaactctt ttacaaaagt
      781 aattctcaga aaagtgtggt ttaatgccac actctttttt gcatgtgagg tataagtggc
      841 aacaaaggta gataagaaaa acgcaatacg acaaggtatt acagaggcgg aaatcgtata
      901 tttccaaaat ttggcaggta aaacatttct gtatgtttgt ggagatgaat attttgaagt
      961 ttcttttcca atagatcact ttctacattt aacaggagtg gagacaagac tttcgaccaa
     1021 ggatttttat aagaatgcaa aaaaatctat tcttacaaat aatcagttct attttgacgc
     1081 aagacatgta tatgcaaatg ccaaaaggaa acttccgtgt ttaaaacgct tgccggaatt
     1141 aacgaatgaa atggtatgtg ttctaaaaaa tatggaaacc atgacaatta catataaact
     1201 cagcgttaca aatttggaat ttacaggaag tgtgacaaga aagccaaaac ggtatactgg
     1261 gaaaaaagat taagaaaaga ataaagagct ggttttaatt gtaaaattta tggggaacta
     1321 acatcagctt attgacatga atttaaaaat aagtataata atagttgagt aattgttcaa
     1381 ctattattat ttggaggtga atatatgcca aaaacgtctt atatttgtaa ttgcgatgta
     1441 attcatgagg atattgtgaa tgatgtgaaa tccaagatgc agccaaaaga tgattatatc
     1501 cagttggctt ctttgtttaa gctatttgga gatggaacta gagtacaaat cttacacgct
     1561 ctagaacaga gtgagatgtg tgtatgtgat cttgcagtgc tactgggggt aacaaaatct
     1621 gcaatttcgc atcagttaaa ggcattacgc cttgcgaatc tggtaaaatt ccgtaaagaa
     1681 gcacagatag tttactactc actggcagat gatcatgtga aagagattat tgacaaggga
     1741 tttgagcatc tttggcagaa ataatatttt ttaacattat agttgagtaa ttgaacaatt
     1801 aaacaaatta taaggagatt atcatgaaac gcatatttct attaaaaggg ttggactgtc
     1861 caaattgttc cgcaaaaatt gaaaaagaag tcggagagtt ggatggagtg caatcctcag
     1921 tggtaaatct gatgaagcag acgattacag tcaatgttac tcagacagcc gcagatacga
     1981 tagccagtca gattgaaacg attgtttata gtcatgagcc agatgtggaa gttcaggaag
     2041 aaaccgttat gaatgttaca aagagttatt cgttaaaagg gttggactgt ccgaattgtt
     2101 ccgcaaaaat tgaaaaagaa gtcggagagt tggatggagt gcaatcctca gtggtaaatc
     2161 tgatgaagca gacgcttaca atcaatgttg ctcagacagc cgcagatacg atagccagtc
     2221 agattgaaac gattgttcat agccatgagc cagatgtgga agtttctgaa attgtacagg
     2281 aatcttatat accggaaaaa aagcaggagg ccaatgaatc ctataacaat gaggataaga
     2341 agttgacagt tcgtttagcg actggtgcag caatctatgc cattggtatg gcattgactg
     2401 tttttgcgaa agtgccactg cctatcgagt tagcttttct cattgtttct tatgttattc
     2461 ttggtggaga tgttgtatgg caggctgtga ggaacatttc aaaggggcgt gtatttgatg
     2521 aacatttttt gatgagtgtt tctacgattg gggcttttgt cattggtgaa tatccagaag
     2581 cagttgctgt tatgttattc tatcaggtag gtgaattttt tcagtcattg gctgttaagc
     2641 gttccagaaa atctatatca gacttaatgg atatacgtcc agattctgct acagtaagaa
     2701 gaaatgggga attgattacc atatctccag aaaatgtctc cattggtgag attattattg
     2761 taaagcctgg tgaaaaaatt ccattagacg gtgtggtatt ggatggagat tctatgctgg
     2821 atacaagggc cttaacagga gaatcagttc cgagaagtgt tcataaagga gacgaagcac
     2881 tttccggttg tatgaatcag acgggtgtct taatgattaa gacaacaaaa gcatttggtg
     2941 aatctacggc ttcaaagatt attgatcttg tggaaaatgc gtcaagccga aaagcaccaa
     3001 cagaaaattt tattactaca tttgcacgtt attatacacc tgtggttgta atcttagcag
     3061 cttttctggc gattctgcca ccgatcattc ttggcggagg ctggacagag tggattcgca
     3121 gaggatttgt tttccttgtg gtatcttgtc catgtgcatt ggttatttca atcccgctga
     3181 ctttcttcgg cggcattggt gcagcatcta aacgaggtgt tcttgtaaaa ggaagcaatt
     3241 atttagaggc acttaataat gtcagcgtta ttgtgttcga taaaaccgga acacttacaa
     3301 aaggtgtttt caatgtgacg gatattttgc ctgcaaatgg attttcaaaa gaacaggttc
     3361 tggagtatgc ggcagaggca gagagttttt ctaaccatcc tattgcaaaa tccattcttg
     3421 ctgcttatgg aaaagaaatg gatcagtcag tgatttttga ttataaggaa atttcaggat
     3481 atggaatcag tgtaatggca ggggaaaaga aagtttttgc tggcaatacg aaacttatgg
     3541 atacagaatg tatagagtac acaacctgtg aaaaagcagg tacaaaagtt tatttggctg
     3601 tagatggtca atatgcagga tgtattttga taacagatga agtgaagccg gacagtaaaa
     3661 aagcaatttc tgacctgaaa catatcggcg tggaaaaaac agtcatgctt accggtgatg
     3721 atgaaaaaat tgggaagtct gttgcagaag aattgcagtt ggatgaatat tatgcacagc
     3781 tgcttcctga ccaaaaagtg gaaaaggttg agcttttaga tagtaaaaag agaccgggaa
     3841 gcaaattggc ttttgttggt gatggtatca atgacgctcc tgtccttgct cgtgcggatg
     3901 ttggtatcgc aatgggtggt cttggttcag atgcggccat tgaagctgcg gatgtggttc
     3961 tgatgacaga tgaaccatct aagctggtgg atgcgattga tgtggcaaaa gcgacaaagc
     4021 aaattgtcat gcagaatata gtgattgccc ttggaattaa gagtgtgttc ctgatccttg
     4081 gtgctctggg tatagctgga atgtgggaag ctgtatttgg tgatgtaggc gttaccataa
     4141 ttgccgtctt gaacgcaatg aggattttga aaaaataaga aacgaggtgg caatgtgaaa
     4201 cggaaattga ttctgttagc agttacaatt gtttttcttg caggtttcgg tgcacttttg
     4261 cactcaccgc cttctatgat tgatgcagtc acaggagcaa caccgaagtc aaaaaaggcg
     4321 gctcaagcct ccgcacagtt ggaaggctct tatgttctcg gtattaatat gatgtcagat
     4381 ggtctcgaca acgagaacac ccggaataaa ttaaaagaat tggcactgga cgattcggaa
     4441 acaaatgaaa cagatctcat gaaaacggac attagttttc ggttatatgt atctgagacg
     4501 gattatccgc ttgtcagtta tgctaagaaa ctctgtgaca ggttgaaaca ggccggtttt
     4561 tccgtagatc tgaaagagta cagtaacaca atgatgctat caagagtggt aagtggaaag
     4621 tatgatgtat tcctggcatc ggatgatttt attgacgtta caacgctaac acagatggac
     4681 tatatgatca tggatagcga agaaatgagg tgagcggaaa tttatgagaa aatggaatac
     4741 gattttgtct gttttaatgc ttctcatttt tatgattcat ggaatcatgg gcagctttat
     4801 gctgaacgga gttggaagta gtgcagggaa acttcttgca tggattggtg ttggtattct
     4861 tgttgtgcat acggtgattg gtgtcatcct gacagttcag agtttacaga cagcgaagca
     4921 atcaggaaaa atgtatctga aacaaaacgt catattctgg gcgagacgag ccagtgggct
     4981 ggcaatactg atcctgctgt tcttccatat tggcttgttt ggaaaggtgc agaatgggac
     5041 atatattttg ttccctttta caacggtaaa gatggtaact cagcttttgt tcgtggcggc
     5101 aatctttgtt catattttta tcaatatccg cccattgctc gtatcgctgg gaatcatcag
     5161 ttataaagaa cgaaggggtg atatttattt gattctttcg gtgctccttc tgtttatagc
     5221 gggcgcagtt attttctatt atattgggtg gcaatatcta tgagtaagac aattattatt
     5281 ataggtgctg gactggcagg actttcagcg gctttgcagg cagcggaaaa tggatgcaat
     5341 gtaaaactgg tttcctccct tccgtcagag cgggcacagt ctgttatggc ggagggcggt
     5401 atcaacgcag ctttgaatac aaaagatgaa aacgacagtc ccgaagaaca ttttacagat
     5461 acaataaagg cagcatgtgg tctggcagat ccaaatgcag tttggggaat gacacaggca
     5521 gcaccggagc tggtgcactg gctgctaaaa cttggagtta aatttaacat gagtggctat
     5581 gatgatgtgg atctgcgaaa ttttggcggg cagaaaaaga aacggactgc ttttgcacag
     5641 agcgataccg ggaagcagat catgacagct atgatagacg ctgttcgcag gaaagaagca
     5701 tctggtatgg tagaacggtt cagccatcat tctttcctaa cacttcgtct gtgtggcaat
     5761 atttgttgtg gctgcgtaat cagggatgaa tacagtcagg agactgtgga attaccgggg
     5821 gatgcggtta ttgttgccac cggtggtatg cacggattgt ttggaaatac aacgggttcg
     5881 ctgagcaata caggagaagt caccgcagaa ttgttccggc ttggtgttcc tctggcaaat
     5941 ggcgagatga tccagtatca tccgacaact gtgaaatgtg gtggaaaacg catgctcatc
     6001 agcgaggcgg ccagagggga aggtggcagg ttgtttgcca tgaaagatgg aaaacaatgg
     6061 tatttcatgg aggaaaaata cccggagctt ggaaatctga tgccacgaga tattaccgcc
     6121 agagagatat ggaaggtcag ccatgaatca gaggtatttc ttgacatgac ggaaatatcg
     6181 gaggagatta tttcaaataa gctatctggt ctggcagacg attgtatgac ctatttgcat
     6241 aaagatatac gaaaggaacc ggtgtctgtt ttaccgggaa ttcactattt tatgggaggt
     6301 attctggtgg atgagcagca cagaacgccg attcagaatc tttacgctgc cggagaatgc
     6361 tgtgcccaat atcatggtgc caaccgtctt ggtggaaatt ctctgttagg agcgttatac
     6421 ggaggacgtg ttgcggcaaa atcagcatgc gaacaggcag atgtagtaga tctatcttgt
     6481 gcgacacaga tagattttcc accagcgtct caaatttcag aaataaagca attaaacaaa
     6541 gtgatgcagg agactatggg cgttgtcaga aatgagaata cgttgttaaa tgggattcaa
     6601 acggtacaag cgctgacagg aaatcttcca ttgcttggca tggcagttct aaagagtgct
     6661 cttgcaagaa aagaaagccg tggtgcacac tggcgggagg attatccaaa gagcaatgac
     6721 gatgattacc ttaaaacaac ggtagccaga tttgatggaa agcagataca gatttccttt
     6781 gtacctgttc cagaaaggag gtgattcact tggtatataa aataagaatc aggcggcagg
     6841 agagtcagaa agcagacagt tattggcagg aatttgagta tgacggaagc aaaaacagct
     6901 ctgttgccac tgttctaaag gaattgaaca gtagaacccc tttgaaagat aactcaggaa
     6961 atatagttac tcccatcagc tgggaatgta gctgtatggt gcgaaaatgt ggggcttgcg
     7021 ccatgctgat taacgaacgt ccgaggttgg catgctctac atttctacat acgttaaaag
     7081 gttctacaat catcttggaa cctttaagca aatttccgct tgtaagagat ttgatcgttg
     7141 accggtcaaa tctgtttgaa aatttgaaaa aactgaacct ttggcttgaa agtgaagctt
     7201 atatgagttc gtggacacat gaaccgagat atcagtcggc acgctgtctg atgtgtggct
     7261 gttgccttga agtgtgtcct aacttctctg caaatgggac tttcgcaggc actgttgctg
     7321 cagtcaacgc atttcggatt ctgaatgaag aacaggaaag cactcatttg aatgagattt
     7381 ctgctgaata taagaagaga ttttttgaag gatgcgggaa gtcgttatct tgtcatgata
     7441 tttgtccgat tggtctgcct gtggaagaac tgcttgtaag gtcgaatgca gcggttgttt
     7501 ggggcaaata aaatggatga taaaagctat aatgaatgta tgaagagaat caaaaactta
     7561 agacatggat cacaccggat cttgcgacgg agtatctcgc aggagccgtg cttctcggag
     7621 cagctccatg taccgctatg gtatttgtct ggagtacgct gacaaaggga aatccggctt
     7681 atacagtagt tcaggtggca tcaaatgaca ttattatatt atttgcattt gtaccgattg
     7741 tgaaatttct gcttggtgtt tctaatgtta gtgttccgtt tcagacgtta tttatgagtg
     7801 tggttctatt tgtagtaata ccacttgcag ccggaatcat aacaaggctg ctggtagtca
     7861 gaaagaaagg tacggaatac tttgagcaga cttttctgca taaatttgat tccgcaacaa
     7921 cagtgggact tttgctcacg ctgatactga tttttatgtt tcagggcgag gtggtgctgg
     7981 acaatccact gcacattata ttgattgcag ttccgctgat cattcagaca ttctttatat
     8041 tctttctggc atttggagta tgcagaatta tcagacttcc gtatgatatt gcagccccgg
     8101 ctggaatgat tggtgcatcg aatttctttg agctagctgt tgcagtcgct gtagctttat
     8161 ttggtacatc aagtccagcg gcactggcaa ctacagtagg tgtattaaca gaagtcccgg
     8221 taatgcttac tcttgtgaag attgcaaaca aattaaagga gaagttcaag tatgaataag
     8281 aaaaaagttg cttttatatg cgttcataat tcatgcagaa gccagattgc agaagctttg
     8341 ggaaaacatc tggcttcaga tgtatttgaa agttattcgg cagggacaga aacaaaacta
     8401 cagattaatc aggatgcagt ccggattatg aaagaattgt atggaattga tatggaagca
     8461 gaaggacaat atagtaagct gattgatgag ataccagtac cggatattgc aatttcaatg
     8521 ggttgtaatg tgggatgtcc gtttatcgaa agaccgtttg atgacaattg gggacttgaa
     8581 gatccaaccg gaaagagtga cgaagagttt aagaaggtta ttgatgagat aaggatgcaa
     8641 atttttatat tgaaacaacg attggatgaa tttgaagaaa actaaagaag ttgagaaatt
     8701 gcagtttgtc gaacggatga gatacaaaaa acatataaga ataatcaaca aggcaggtgg
     8761 ttttataaca agactgtctg ccttctttta tgccagcaga ggctatttca aaggggcatc
     8821 caaaagacat acaatatata ggctcaaatg gcgaaagtgc ccatttgggc ctattattgc
     8881 atgaattcat atgttacatc cagagcaaga tccacccgtg tattacagta ttgtcatttt
     8941 gacaattttg tattacttac gagtagcaga cttgatgggg attacgtccc catacccacg
     9001 tgaaaatata attgctggca attacatttt agcagacacg caagcgtttc tgagtaagtg
     9061 tcacagacaa caaaataagg aaattttgat aaggcattca cctggaatag gtgagtgttt
     9121 tttgttttca aatattcaat taaccgaaaa aatttaaaaa atttcatcag ggggctgtaa
     9181 aaatgcctct cagcgtttcg tattaatgaa agggtatttg ggcgggaaaa ataaaaaact
     9241 ttcctcaaga gcctgtattt atgcccttca tcttttgaat atatgtaagg acatttttga
     9301 gccggcataa aaatgatttt tacaataatt agaaacagaa atgaggcgag aaaagaatga
     9361 aatatgaata catgaaggag tcagagcaga tgcttcagta cttccagttt ccgaagtttt
     9421 tattaaagct gcgaatttct caaactgcaa aattccttta tatgattttg tatgaccggg
     9481 cacggatatc gagaaagaat agctggatag acaagtatgg aaatgtttat ctgatatttc
     9541 caatagatga attgtctgtt caaatcgata aatgcaaatc ttctgtaaaa acagcgttga
     9601 aggaattaga tgatgtggga ctattggttc gcagatccgg tggattttca aaacccaatc
     9661 atttatatgt gaaaattcca tctgatgaga taggtttaca gccggttgac aataaggcgg
     9721 ttgaaaagat agttgcaaca gagccggaaa agccaccttc atctggtcgt aaaaatggct
     9781 gtggaggagt cggaaatgtg gcacctagta aagtaactga gaaatataaa agtaataaat
     9841 atcatgaagt aaattattgc tatggggaag gagagagttt gtgatgagag aagaagatac
     9901 tgtatgtgta ggcagtgatg gcttgaaata ctgcaaagtc tgtggggaag cgaaagaagc
     9961 atttttcccc aaggatagat ttatgggaat gaagaaacat tccaggcaat gtgcctgtga
    10021 cagaaaagca tatgaagaag aacaaaaata ttttaaagac aaagagcacc gggaattagt
    10081 cagcagaaat acgagcatct gttttgacga gagcagaatg gaagagtgga catttgagaa
    10141 tgcagatatg tcagatacgg taatgcatag agcaaaaaaa tatgttgata actgggagga
    10201 aatgaaaaga aatcatatag gctgtttgtt ctggggaccg gttggtaccg ggaaaagttt
    10261 tattgcgggg tgcattgcca atgaacttct taagcaagaa gtaatggtaa agatgacaaa
    10321 tttcaatacc attattgatg atatatttcc actggcagac aaaacggaat atatcaatgc
    10381 attggcgtct tatcagcttt tgattattga tgatcttgga gtggaacgaa attcagaata
    10441 tgcgttagga attattttta gcgtcataga tcgaagaatc cgttcaggac gacctttgat
    10501 cattacgacc aatcttccgc tgaaagaaat aaaaaacgag accatgttag ataaaagacg
    10561 tatctatgac cgtattttag aaatgtgtac gcctatgtat gttggaggca caagtaagag
    10621 agaagtgatt gcaagtatga aaatggagaa agcgaaaacg ttgttgaata caaacagagg
    10681 ggaggaggac tgcgaatgaa tcatacagaa aaaacaatac ctgtttggga gaaatattct
    10741 ttaaatgtat ccgaagcagc agaatattac ggaattggag aaaagagatt gagacaaatc
    10801 gcaggtgaaa atgagggagc ggatttcatt ttggaagtag gttctcatat tcgattcaaa
    10861 aggaaattgt ttgaagatta tctggataca gccagcacag tttaagtgac agaatagaag
    10921 aaatagtaat gaaaataatg ttcattttat cttagcgaag gaaaggtctt gtggtataat
    10981 gaataaaccg agacggtctt ccaagttaaa tgaacatttg atgaaggaga ctaaaatatt
    11041 atgagtgaaa aaaggagaga tcatagagga cgtatattac acaatggaga aatacagtta
    11101 tctgatggca gatatcgatt taagtatgtc gatgagatgg gaaaggagcg ctgcgtatat
    11161 agctggcgct tagaccataa cgatgcaact ccgaaaggaa agcgccgtac tttgtcgctt
    11221 cgggagatgg agaagaaaat ccaggcggac cattttgagc agattgcaac aaatggcgga
    11281 aatatgacgg tactggaact ggttgaaaaa tatacatcaa caaaaaccgg tgtcagacct
    11341 actacagttg caggatacgg aacagttatc aatttattga agaaagatcc atttggaaaa
    11401 agaaggattg atacggttcg gatttcggat gcaaaatgtt ggctgataca tcttcagcag
    11461 gtagaaaaga aaagttatag ttccatccat tcaatccgag gagttcttcg tccggcattc
    11521 cagttggcag tggatgatga cctgatcagg aaaaattcat ttcagtttca gctaatggaa
    11581 gtggttgtga atgacagtgt gacaagagag gcaatcagca gggctgagga acgaaagttt
    11641 ctacgatttg tgaaggagga tcctcatttt tgcaggtatt atgagggaat ctacatatta
    11701 tttaaaaccg gccttcgcat ctcggaattt tgtggtttga ccatttctga cattgatttt
    11761 aaggagcata cgatcaacat cgatcatcaa ttgcagaaaa aatcaaaaat cggatattat
    11821 attcaagaga ctaaaacaac cagcggaacg agaaagatac ctatgactgc agatgtagag
    11881 gaatgctttc ggaaaataat agaaaaacga aacccaccca aagcagaacc tatggtagat
    11941 ggaaaaagtg gattcttata ctttgataaa aatgaaagta tctgttattc cctgcactgg
    12001 gagcattatt tccaacacat cattcagaag tataataata cttacaaagt acagatgcct
    12061 gtcattacac cgcatgtatg ccgacacacc tattgctcaa atatggcaaa atccggaatg
    12121 aatccaaaag cattgcaata tttgatgggc cactcagata tcagcgtaac gctgaataca
    12181 tatacgcatg taaatcttga ggatgccagg gaagaagttg cccggattca ggttgtgtaa
    12241 ttacgatttt taattgaaaa tagcaaggtg taaaatggaa aaacatacac cttattttac
    12301 accttttgct gacgatatta tgcgaaaata aaccaggtta tgccagaaag caaaaattta
    12361 caaaggctta caaagcccga aaaaccaaga aaaactaaga aatgcgaggt tatgcaacaa
    12421 tgataaaagt actatttatc tgccacggca ggatttactg ttcgtgagaa aaagtcttaa
    12481 atcgtcttaa atacttctat aaatagcatt tcttgtgttc aattctcgat tttaccaatg
    12541 atttaccaat atttctggag agtcagactt gcagaaacaa caaaccagaa tgaggagatt
    12601 aaaaatatga gcggattaaa gaaacacatt tatgaagaga aaaacggact gcattacact
    12661 ctgaatggag attattattt accagatttg aaattgccgg aggaacaccg ccctatcgga
    12721 aagtacggac ggatgcaccg ggaatattta agagaagtcc acccagccag attgaataca
    12781 ttgaccctga caggggaatt atggacatat cttgcagatc tgaacgaaca ggcacagaag
    12841 cgattagata caatcataga gcagatgaaa gctgctgagg gggtcacaga agaattaaag
    12901 agtatctgtc agatggaatg ggtgcagcgt tgcaataaca ttcacaatcg ggcagaagaa
    12961 attgttttgc atgagatgat ttattcataa cggtatggta gaatgattat gataaatcgg
    13021 agttgtgcgc ccagataagg gcgagtagtc tagcaggtgg aatgcctgtc tggtaaggcc
    13081 taaccaaccg ccagtagcga gtcttgggtg actgtcagta atggtagttg ctaagcgtag
    13141 acagcgagaa aatagagagt gtgattgagc ctcgaaattt tgacatttag aaggctgacg
    13201 ttctaatttc gacggaaagc aatacaaatc aattcgcatt ggtgagaaat ggtttgcttc
    13261 tgcggggtca aagagcactt tatgttttac attgtgatta ttcagtcaac tggggagagc
    13321 ctattgtttc ttgccattgc aagtatggca aacaactgca aaacaggaga atgtcaaaag
    13381 aacagtaggc agtcggatag cttcatagta ctgaagaagt tgggtaatgc caacggagga
    13441 aagggagcta cataataatg gtctttctga ggacacatca accgtactca gggacggagg
    13501 tattgatgga aacgaaatta gaaagaatag cagaaatatc ggcaaattcg ccgggaccag
    13561 agttcacatc gttgtatcat ctaatcaata aagaaatgct tttgcaatgt cacaaagaat
    13621 tagacggaaa caaagcagtc ggtgttgatg agattactaa gaaagagtac gggagaaatc
    13681 tggagcaaaa cttagatgac ttggtagaaa gactgaaaag aaaatcatac aaaccacagc
    13741 catcaattag ggtatatatc cctaaaagca atggaaaact tcgaccatta ggaattgcat
    13801 gctatgagga caaaatagtc caattagcat taaagaagat attggaagct atctatgaac
    13861 cgagatttct gaactgcatg tacggattca gaccaaatcg aggatgtcat aacgcaataa
    13921 aagaactgtg taagagatta aacaacacga aaatctgcta tattgtggat actgacatca
    13981 aaggattctt cgaccatatg aagcatgaat ggattatcaa gtttctcaaa ctttatatta
    14041 aagaccccaa cataattggt cttgtcaaga agtatcttaa agtgggagtg ctggataatg
    14101 gtgaacttat ggcgaatgaa gaaggttcag ctcaaggtgg attatgcaaa gcttagcata
    14161 gatttcccta tgcaaagtag cagact
//
