LOCUS       c00011_gnlPro..        15033 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFKHEOKF_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:12:19
            Original ID  :: gnl|Prokka|KFKHEOKF_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15033
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15033
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1805:5033]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1806..5033
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15033
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15033
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..1628
                     /locus_tag="ctg11_1"
                     /transl_table=11
                     /translation="KYRVYYKGRKGWTRMVDTTSTSYIDKDVSSGRNYTYTVRCISADG
                     KSFTSGYDSKGTPVKYIAAPEISKLENVNGGVKISWGKVSGATKYRVYYKGSKGWTRMA
                     DTTSTSYIDKDVSSGRNYTYTVRCITSDAKKFTSGYNPTGKSVKYVATPKISKLEVTYD
                     GVKLTWNKVAGAEKYRVYYKDRNGWTKLADTTGTTMLDMNVVSKEFDLSVDDIYYTVRC
                     ISKDAKSFTSGYDSKGTPIGDHQDCPEIYSIGAVNNGVEMHWTGDAPKFRVYIKENGSW
                     KRIAETYDNYYVHKGARSGSNTYTVRGVSKDGKKFTTMFNPTGVTYRYKTSDKTRDAYI
                     NYMMNHQSEWMPSLGSDHNLSGVMFLDFDFDGVPELVAQKADSNEYGFHSVVYKFEDGK
                     LKRVGNVNDGFSIYYNKTAKKYEVHDLDIYLNVDDGYYWSGNSIITYDGENLFANMYSS
                     RGVSEESNNNIYYSYFDGNDKNISRAKYNEINLKQFNNCVNAHMFTQFIATGYGDTSVW
                     GEKTTAENKQSLLDAYNSFSYEKY"
     CDS             complement(1806..2846)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_2"
                     /sec_met_domain="IlvN (E-value: 1.1e-82, bitscore: 269.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.1e-60, bitscore: 194.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYTKNMTAPIYYQSDCNLDLLKGKKIAIIGYGSQGHAHALNLK
                     DSGCDVIIGLYKGSKSWAKAEAQGFKVYTSAEAAKQADIIMILINDEKQAALYKNDIEP
                     NLEAGNMLMFAHGFNIHFGCIKPPKDVDVTMVAPKGPGHTVRSEYQVGKGVPCLVAVEQ
                     DATGQAKDLALAYALGIGGARAGVLETTFRTETETDLFGEQAVLCGGVCALMQAGFETL
                     CDAGYDPRNAYFECIHEMKLIVDLIYQSGFAGMRYSISNTAEYGDYITGPKIITEDTKK
                     AMRKVLSDIQDGTFAKDFLLDMSDAGSQVHFKAMRKIAAEAPAEVFGKEVRKLYSWSDE
                     DKLINN"
     CDS             complement(2907..3398)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.5e-29, bitscore:
                     94.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYTLSILVENQAGVLSKISGLFSRRGFNIDSLAVGVTQDPSVSR
                     ITIVANGDEYIVEQLEKQLNKLIPVIKVKRLNEGEFISRELVLIKVHCAASKRAEIVKT
                     VEIMQAKIVDVSPSSVTVEYCECASRINTLVDLLKPYGIREIVRTGTVAIDRGTASVSV
                     "
     CDS             complement(3411..5033)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.1e-42, bitscore:
                     137.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISGAEIMVKCLEAEGVDIVFGYPGAAICPFYDKVYDSSITHILV
                     RQEQNAAHAASGYARCSNRPGVCVATSGPGATNLITGIATAYTDSIPIVAITGQVRSDL
                     LGRDVFQEADITGACEPFVKHSYLVSKTEDLPRVFKEAFHIASTGRPGPVLIDIPVDIQ
                     ENEIESFEYPESVNIIGYKPNTKGHAIQVKKAVEAINASKRPVIVSGGGVLSSGIKLKL
                     QKFAETTGIPVISTMMGIGVMPSEHELYLGMLGTHGKAVANRALHEADLVIVCGARLGD
                     RAVAAPDQMSENTKVIHIDIDPAEIGKNVKTEIPIVGDMKNVINMLLDSIGDYKVTTMW
                     SETVKNWKKDLYREPPVFDGFVEPRTLVGHLSAMFRSKAILVADVGQNQIWCANNFRIR
                     EGRFLTTGGMGTMGYSIPAAIGAKFARPDRDVIVICGDGSFQMGLNELATIAGNQLGIK
                     IIIMKNARLGMVRELQDKHYGGRHSATILNGDPDFLKIADAYGIDHAEAHSNKEAENII
                     KGIVDSEKPFILVCDVHPDTPSI"
     CDS             complement(5229..6470)
                     /locus_tag="ctg11_5"
                     /transl_table=11
                     /translation="LKKIFLLLVTTLFLLSLYGCNTSSSSNNPTEQTTVTNTDDLSLDS
                     DIETTELNHDYEIYNNGKKVDTLNLYGLFKQIDNGFIYSKINKDSPNEMEYYRYYLDKK
                     NSVKLGSIKNWSMQIHDKAYVNNHLCFTSSTGDITDEENRTLEFIDIDLNKNKMTTVFS
                     DKGGFPYDTVTGADNLVIITKVLDNGTSLELYDTETQKFKQLKYLEFDDKNSIGETIRK
                     VSIDKSTKTISLLVLDCISQNEASLKIETYDYDMNFLKSYDISNISDDSNELIQGVQVF
                     DFKNNYLFYQNFSITRCIGYIDSDKLKKSDISEDVDDTFSIVSASEDDSDTNLLYKRAE
                     SSSENNYIYLFDTTNKTMKETKFNIEEKGYTIGGISRIGKDNLMILMSPDNADKKSDLN
                     SRIYFTKLSDLNFQ"
     CDS             complement(6680..9232)
                     /locus_tag="ctg11_6"
                     /transl_table=11
                     /translation="MRYKYQLDNLNCAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKS
                     ETQNPVSESQAICDSIEDGVTVVDKTPKTNLKKYTYTLDNLNCAHCAGKIEAKIAETDG
                     FEDVSFNFATKLLNFKSEKQNPVSEIQVICDSIEDGVTVVDKTPKTNLKKYTYTLDNLN
                     CAHCAGKIEAKIAETDGFEDVSFNFATKLLNFKSEKQNPVSEIQAICDSIEDGVTVVDK
                     TPKNDVTTKAEPEITKKKINHDTIFLAISIVLAVVSEILHLTLDGVTAVHYVVLAACFV
                     ATLLSGYKVFIKGAKNILKLRIDETTLMAVAVIAAFCLGDFVEAAMVTILFSIGEIFED
                     RAVDASRRDIEKLANIRPDTATIIVDGAEQIVPAESVEIGSIIEVKPYERVPLDGVIIK
                     GKTTLDTSALTGESLPVDASEGSEVLSGAINGSNLITVKTTKHFGDSTATRILQLVEDA
                     AAQKGNSEKLISRFASVYTPVVVLIAAAIAVIPPLCGLGAFSEWLYRALVCLVASCPCA
                     IVISVPLSYYSGIGAASEVGVLIKGGKYIEALAKADTFVFDKTGTLTSGKLSVNKVNTV
                     GSYSADEVLALAAASEKYSAHPIASAIREKANGLELPELSDYSESAGHGTSAVYNGKTI
                     QCGGSKILSDEQKKIANKDDSVFVIYDGQLIGSLNVSDTVRPEAKEVISQLKALGVKNT
                     VMLTGDRQQPAENVKNELGLSECHAELLPAQKLELFKGLKSKSKGACFVGDGINDAPVL
                     SASDCGIAMGFGSEAAIEASDAVLASGTLKQLPKAIKIARSVINTVKGNIIFALSIKAL
                     VIILAAFGLAQIWMSVIADTGVSVVCVLIAARLLKKKY"
     CDS             complement(9245..9562)
                     /locus_tag="ctg11_7"
                     /transl_table=11
                     /translation="MENKEKTTTPEMPDIDVLFELADLFKVFGDSTRLRIMYTISENEM
                     SVLNIAEALSMEQSTISHQLRVLRQNKLVRVRREGKQIYYSLDDDHVKRIIEMGLDHVL
                     E"
     CDS             complement(9766..10482)
                     /locus_tag="ctg11_8"
                     /transl_table=11
                     /translation="MSETAKEPKKISKRSSEEKIEIIVAIFLGITALATAWASWIGSLH
                     GGNQATNYTKSNNLSSEGNSMWNEASQNLMQDMITWNDINEANLNYQYAESKNDKAEME
                     KYQYQIDQLMSDNCTEEFLEAINWAMDQKENVTPFMKDGYTESYFAEAQATIEESDKLL
                     EQGKKDNANGDAFGLVSVIYSVVLFMLGIVGTFKNLPNRRIVLGVAVAGFILATIYMFT
                     IPMPTGFNILSYFGMA"
     CDS             11164..12456
                     /locus_tag="ctg11_9"
                     /transl_table=11
                     /translation="LEKFVVTGGKPLSGEVTISGAKNAAVAIIPAVILCDEPCQIENIP
                     NISDVSLISRILQQMGANVRRINRSSLYIDPTKIRTCNAVTDLVRGMRASYYLLGALLG
                     KYGKAKVALPGGCNFGVRPIDQHLKGFEALGATTQLVDGAIIEAECDNLVGTHVYLDVV
                     SVGATMNIMLAASKAKGQTIIENAAREPHIVDLANFLNSMGADVRGAGTDVIKIRGVEY
                     LHGITYSIIPDQIEAGTYMCAAAATRGCITVKNITPKHLESISAKLREMGVKITEYDEA
                     LKVDASSAPLKRCNIKTMPHPGFPTDCQPQFAALLMSVPGTSIINENVWDNRYQYVSEL
                     IRMGAQISVEGRLAIIEGGVPLTAAPVKATDLRAGAAMIIAALEINGTTEISNIQFIER
                     GYEDVVEKFRALGADIKKVYFTGDNEQELGA"
     CDS             12579..13367
                     /locus_tag="ctg11_10"
                     /transl_table=11
                     /translation="LARAVPLFSGSKGNSYYIGSASEGVLIDAGRSCKQIENAMLANGL
                     DMGSIGAVFITHEHTDHCSALRVLAKRYGFKVYSSLGTLNALRAGNKLDPNTDADVITD
                     EVVIGNMRVQRIDTPHDAAESCCYRVTAPDGKSALIATDMGVMLPDVRTAAEQSDFVVL
                     ESNHDINMLKNGFYPYPLKQRILSNRGHLSNEACAKELVNLVEKGTLRLMLGHLSEENN
                     TVPLAMSTSVDLLTSNGMKYKSDYSLDVAPSVSTTKAIIF"
     CDS             13389..13874
                     /locus_tag="ctg11_11"
                     /transl_table=11
                     /translation="MIKINIICIGKIKEKYFTDAIAEYAKRLTAFCKFNIIELSEERIK
                     NNIPNRSQIDEVIFSEGKRIMQKISPSDYVVAMCIEGKSMSSEELSKLIDNASVSGKST
                     VDFIIGGSYGLDESVKKRADVRLSMSRMTFPHQMARMILSEQIYRAFEISSNGKYHK"
ORIGIN
        1 ctaaatacag agtttactac aagggccgta aaggttggac acgaatggtc gatacaactt
       61 caacatcata tatcgacaag gatgtttcat cgggcaggaa ttacacctat actgtaagat
      121 gtatttctgc tgacggaaag agctttacaa gcggttatga ttcaaagggg acacctgtaa
      181 aatatattgc cgcccccgaa atttcaaagc ttgaaaatgt aaacggcggt gtgaaaatct
      241 cttggggcaa agtaagcggt gcgactaaat acagagttta ctacaaaggc agtaaaggct
      301 ggacacgaat ggccgataca acttcaacct catatatcga caaggatgtt tcatcgggca
      361 gaaattacac atatactgta agatgtatta catcagacgc aaagaaattc acaagcggtt
      421 ataacccgac aggcaagtcg gtaaagtatg ttgctacacc gaaaatttca aaacttgagg
      481 ttacatatga cggcgtaaag ctgacatgga acaaggtcgc aggtgctgaa aaatatcgtg
      541 tgtactacaa ggacaggaac ggttggacaa agcttgccga cacaacaggc acgactatgc
      601 ttgatatgaa tgttgtttca aaggaatttg atttaagtgt tgacgatatt tattacacgg
      661 ttcgttgtat cagcaaggat gccaagagtt ttacaagcgg ctacgattca aagggtacgc
      721 ccattggcga tcatcaggat tgtcccgaaa tttacagcat tggtgcagta aacaacggtg
      781 ttgaaatgca ttggacggga gatgcgccaa agttccgtgt ttatattaaa gaaaacggtt
      841 cttggaagag gatagcagaa acttatgaca actattatgt tcacaagggt gcaaggtccg
      901 gcagtaacac ttatacagta agaggtgttt caaaagacgg taaaaagttt actacgatgt
      961 ttaacccaac cggtgtaaca tacagatata agacatctga taaaacaagg gatgcttata
     1021 tcaattatat gatgaatcat cagagtgaat ggatgccaag cttgggaagt gatcataatt
     1081 tgtcaggtgt tatgtttttg gatttcgact ttgacggagt tccggaactt gttgcacaaa
     1141 aggctgattc caatgagtat ggtttccatt ccgttgttta caaatttgaa gacggtaagt
     1201 taaaaagagt gggaaatgtt aacgacggtt tttcgatata ctataataaa actgccaaaa
     1261 agtatgaggt tcacgacctg gatatatatt taaatgtaga tgacggttac tattggtcgg
     1321 gtaattcaat aatcacatac gacggagaga atctttttgc aaatatgtat tcgtcaagag
     1381 gcgtaagcga agaatcaaat aataatattt attatagtta ttttgacggt aatgacaaaa
     1441 atatttcacg ggcaaaatat aacgaaatta accttaaaca gtttaataat tgcgtaaatg
     1501 cacatatgtt tacccaattt attgcgacag gttatggtga taccagcgta tggggtgaga
     1561 aaactaccgc tgagaataag cagtctttgc ttgacgctta taattctttc tcctatgaga
     1621 agtattgatt atttaaaaat tgataagttt taactgcaaa agggttcagc cgtaaaaagc
     1681 tgaacccttt tattgcacaa caaaaaacgg ttcagccaaa ttgactgaac cgttaatctg
     1741 tactatgtaa tgctcgggtg acagaaattt gaatatatca aactaactac acgaactaaa
     1801 aaacattagt tgttgatgag cttatcttcg tcagaccagc tgtagagctt tctaacttcc
     1861 ttaccgaata cttcggcagg agcttcggca gcgatctttc tcatagcctt gaagtgaacc
     1921 tgtgaaccgg catcgctcat gtcaaggagg aagtccttag caaatgtacc gtcctgaatg
     1981 tcagaaagaa cctttctcat agccttctta gtatcctctg tgatgatctt tggacctgtg
     2041 atgtagtcac cgtactcagc tgtgttagag attgaatatc tcatgcctgc aaaacctgac
     2101 tgatagataa ggtcaacgat gagcttcatc tcatggatac actcaaagta agcgtttctt
     2161 gggtcgtaac ctgcatcgca aagtgtttca aaacctgcct gcataagtgc gcaaacaccg
     2221 ccgcaaagaa cagcctgctc accgaagagg tctgtttctg tttctgttct gaatgttgtt
     2281 tcaagaacgc cggctcttgc accgccgata ccgagtgcat atgcaagtgc gagatcctta
     2341 gcctgacctg tagcgtcctg ctcaacagca acgaggcaag gtacaccctt accaacctga
     2401 tactctgaac gaactgtgtg acccggtccc ttaggagcta ccattgtaac atcaacatcc
     2461 tttggaggct tgatgcaacc gaagtgaatg ttaaagccgt gagcgaacat aagcatattg
     2521 cctgcttcga ggtttggctc gatgtcgttc ttgtaaagag ctgcctgctt ttcatcgttg
     2581 ataagaatca taatgatgtc agcctgcttt gcagcctctg ccgatgtata taccttaaag
     2641 ccctgtgcct cagcctttgc ccagctcttg ctgcctttgt aaagaccgat gattacatcg
     2701 caacctgaat ccttgaggtt gagagcatgt gcatgaccct ggctgccgta accgataata
     2761 gcaattttct tacccttgag aaggtcaagg ttacaatctg actgatagta gattggtgct
     2821 gtcatgttct ttgtgtagtc tttcatatta aagtcctcct taccgcaaac gcggcatata
     2881 aattagaata tatgctaact gtaagattaa acggaaaccg aagctgtgcc tctgtcaatg
     2941 gcaacagtac ctgttcttac aatctcacgg ataccataag gcttgagtaa gtcaacaagc
     3001 gtgttgatgc ggcttgcaca ttcgcagtac tcaacggtaa ctgacgaagg ggatacatca
     3061 acgattttcg cctgcataat ttcaaccgtt ttgacaattt cggctctttt tgaggcggcg
     3121 cagtgaacct tgattaaaac aagctcacgg ctgataaatt cgccctcgtt aagccttttt
     3181 accttaataa cgggaatgag cttgttgagc tgtttttcaa gctgttcaac aatgtactcg
     3241 tcaccgtttg caacgattgt gattcgggaa accgacgggt cctgagtaac acctactgca
     3301 agtgagtcga tgttaaaacc tcggcgagag aaaagtcccg aaatctttga aagaacgccc
     3361 gcctgatttt caacaagtat tgataatgta tactgcattt tatcacctca ttaaattgac
     3421 ggagtgtcgg ggtgaacatc gcaaacaaga atgaacggtt tttccgaatc aacaataccc
     3481 ttgatgatgt tttcggcttc cttgtttgaa tgagcctctg catggtcaat gccgtaagca
     3541 tcggcaatct tcaagaagtc gggatcaccg ttgagaattg ttgcggagtg tctgccaccg
     3601 tagtgtttgt cctgaagttc acgaaccatt ccgagtcgtg cgtttttcat aatgatgatt
     3661 ttaattccga gctgattgcc tgcaatagtc gcaagctcat taagccccat ctgaaaactg
     3721 ccgtcaccgc agattacaat aacatcacgg tcgggtcttg caaactttgc accgattgcg
     3781 gcgggaattg agtaacccat tgtacccata ccgcctgttg tgaggaatct gccctcacga
     3841 atacggaagt tgtttgcaca ccagatttga ttttgtccta catcggcaac gagaattgcc
     3901 tttgagcgga acattgcgct gagatgaccg acaagtgttc tcggctcaac aaagccgtca
     3961 aaaacgggag gctcacggta aaggtctttt ttccagttct ttacggtttc gctccacatt
     4021 gttgtaacct tgtaatcgcc gatgctgtca agcagcatat tgatgacatt tttcatatcg
     4081 cctacaatcg gaatttctgt tttaacattc ttaccgattt cagcagggtc aatgtcaatg
     4141 tgaattacct ttgtgttttc actcatctgg tcgggagccg caacagctct gtcaccgagt
     4201 cttgcaccgc atacgattac aaggtcggct tcgtgaagag cacggttggc aacagccttg
     4261 ccgtgagtgc cgagcattcc gagataaagc tcatgctcgc tgggcataac accgatgccc
     4321 atcatagttg aaataacggg gatacccgta gtttctgcaa atttttgaag tttaagcttg
     4381 atacccgaac tcagcacgcc gccgcctgat acaataacag gacgcttgct tgcgttgatg
     4441 gcctcaacag cctttttaac ctgaattgcg tgtcccttag tgttcggctt gtaaccgata
     4501 atgtttacgc tttcgggata ttcaaaactt tcaatttcat tttcctgaat atcaacggga
     4561 atgtcgataa gtacaggacc gggtctgccg gttgaggcaa tatggaaagc ctctttgaaa
     4621 actctcggaa ggtcttctgt tttgctgacg agataactgt gctttacaaa cggttcacaa
     4681 gctcctgtga tgtcagcttc ctgaaagaca tctctgccga gaaggtcgga acgaacctga
     4741 cctgtaatgg caacaatcgg aatagagtcc gtataggcgg ttgcaatgcc tgtgatgagg
     4801 ttggttgcac cgggaccgga agttgccacg caaacaccgg gacgattact gcatcttgca
     4861 tagccgcttg ccgcatgagc agcgttctgt tcctgacgaa caagaatgtg ggtaatgctc
     4921 gagtcgtaaa ctttatcgta aaatgggcag atagccgcac cgggataacc aaagactatg
     4981 tcaacgccct cggcttccaa acattttacc ataatttcag caccgctgat cattatgttt
     5041 tgtccctcct atccttttta ttgtgagcaa aaggtgtttt gtaacattaa atataccttt
     5101 ttgctttacc gctaattata caataaatac cttaaaaagt aaagagcagt attgcccata
     5161 aattaaattt tttgcaggat tttgacagat aatttgcaaa atgaatttta attgatttta
     5221 ccgcctgttt actgaaaatt taagtcgctt agttttgtaa agtatattct tgaattaagg
     5281 tcactttttt tgtctgcatt atcaggggac atcaatatca tcaaattatc ttttcctatc
     5341 cgtgatatac cgcctatagt gtaccctttt tcttcaatat taaattttgt ttctttcatt
     5401 gttttgttgg ttgtatcaaa aagatatatg tagttatttt ctgaacttga ttccgccctc
     5461 ttatacaata aatttgtatc actgtcatct tcagatgcgg atactattga aaaagtatca
     5521 tctacatctt ctgatatgtc ggattttttc agcttatcgc tgtctatata tcctatacat
     5581 cttgttatgc tgaaattttg atagaataga taattgtttt taaaatcaaa aacctgtacg
     5641 ccctgaatta attcgtttga atcatctgaa atgttggata tatcatagct tttgagaaaa
     5701 ttcatatcat agtcataagt ttctattttt aaagaagctt cgttctgtga aatgcaatcc
     5761 aaaaccaaaa gagagattgt ttttgtactt ttgtcaattg aaacttttct tatagtttcc
     5821 ccgatactgt ttttatcatc aaactctaaa tattttaatt gcttgaattt ttgagtttcg
     5881 gtatcataca gttccaaaga agtaccgttg tccagcactt ttgtgattat gacaagattg
     5941 tctgctcctg taacagtgtc atatggaaat ccgcctttgt cagaaaatac agtcgtcatt
     6001 ttgtttttat taaggtcgat atcaataaat tcaagagttc tgttttcttc gtctgtaatg
     6061 tcgcccgtgc ttgacgtaaa gcaaaggtga ttatttacat aagctttatc gtgaatttgc
     6121 atagaccagt tttttattga accaagtttt acactgtttt ttttatctaa ataatatctg
     6181 tagtattcca tttcatttgg agagtcttta ttgatttttg aatatatgaa gccgttatca
     6241 atttgtttaa ataagccgta aagatttaaa gtatccacct ttttgccgtt attgtaaatt
     6301 tcataatcat gatttaattc tgttgtttca atatctgaat caagagataa atcatctgta
     6361 ttcgttacgg ttgtttgttc agtggggtta ttgcttgatg aagaagtgtt acatccatat
     6421 aatgaaagta aaaataaagt ggttactaat aataaaaata tctttttcaa attaatctcc
     6481 ccgaagttta tttatcagtt acaagcactg acaaaaatat tataatttat ataattataa
     6541 aagtcaatta aaagtcaatg atttcaaaat actataatat aagattatgt ttagaaaaat
     6601 tttggcaaat gaaagcaccg tgaaacttgt gaaagctcac ggtgctttat cataataaat
     6661 gatatgattt gcaaaaaaat caatatttct ttttgaggag tcttgcggct atgaggacac
     6721 agactacgct gacgcccgtg tcggcgataa cagacatcca gatttgtgca agaccgaatg
     6781 cggcgaggat aattacaaga gccttgattg agagggcaaa gatgatgttg cccttgacag
     6841 tgttgataac acttcttgca attttaattg cctttggaag ctgtttgagt gtgcctgatg
     6901 cgagaactgc gtctgacgct tcaatggcgg cttcactgcc gaatcccatt gcaataccgc
     6961 agtcgcttgc cgaaagaaca ggggcatcat tgatgccgtc gcctacaaag caagcaccct
     7021 tggattttga tttcaagccc ttgaaaagct caagcttttg agcagggaga agctctgcgt
     7081 gacattcgga aagtccgagt tcgtttttaa cattttcggc aggctgttgt ctgtcgcctg
     7141 tgagcattac cgtgttcttg acaccgagcg ctttaagctg tgagataacc tcttttgcct
     7201 caggtcttac cgtatcgctg acattgagag aaccgataag ctgaccgtca taaattacga
     7261 aaacagaatc gtctttattt gcaatcttct tctgttcgtc cgaaagaatc tttgaaccgc
     7321 cgcactgaat agtcttgccg ttataaactg cgcttgttcc gtgaccggca ctttcgctgt
     7381 agtcggaaag ctcgggaagt tcaagaccgt ttgccttttc tctgattgcg gaggcaatcg
     7441 gatgagcgga atatttttcg cttgcagcgg caagagcaag aacttcgtcg gcactgtatg
     7501 aaccgacagt attaaccttg tttacgctga gcttgccact tgtgagcgtg cctgttttat
     7561 cgaatacgaa tgtgtctgct tttgcaagag cctcaatata ttttccgccc ttgatgagta
     7621 caccgacttc ggatgccgca ccgatacccg aatagtagga gagaggtacg gaaataacaa
     7681 tagcacacgg acatgacgct acaagacaaa caagtgcacg gtagagccat tcgctgaatg
     7741 ctccgagtcc gcaaagcgga ggaattactg cgattgcagc tgcaatgagt acaacaaccg
     7801 gtgtgtaaac agaggcaaat cttgaaataa gcttttcgct gttgcccttt tgagcggcgg
     7861 catcttcaac aagctgaaga attcttgttg cggtactgtc gccgaaatgt tttgtggttt
     7921 tgacagtaat aaggttactg ccgttgattg caccgctgag tacctcactg ccctcgcttg
     7981 catcaacagg aaggctttcg cctgtgagag ccgatgtgtc gagagtcgtt ttacctttaa
     8041 taataacgcc gtcaagcgga actctttcgt atggcttgac ttcaatgata cttccgattt
     8101 caacgctttc ggcaggaaca atctgttccg caccgtcaac aataattgtt gctgtatcgg
     8161 gacgaatgtt tgcaagcttt tctatgtcac ggcgggatgc gtcaactgct cgatcctcaa
     8221 aaatttcacc gatagaaaag aggattgtta ccattgccgc ctcaacaaaa tctccaagac
     8281 agaatgccgc aattaccgca acagccataa gcgttgtttc gtcaattctc agctttagaa
     8341 tgttttttgc acccttgata aataccttgt aacccgaaag aagtgttgca acaaaacacg
     8401 ctgcgagtac aacataatga acagccgtaa caccgtcaag tgtaaggtgg aggatttcgg
     8461 acactacagc aagtacaatt gaaattgcaa ggaagattgt gtcatggttg attttctttt
     8521 tcgtgatttc gggttctgcc tttgttgtga catcattttt cggagttttg tcaacaacag
     8581 ttacaccgtc ctcgatgctg tcgcagattg cctgaatttc ggaaacagga ttctgctttt
     8641 cgcttttgaa gttgagaagt tttgtcgcaa aattaaagct tacatcctca aagccatctg
     8701 tttctgcaat tttagcctca atcttgcccg cacaatgagc gcagttgaga ttgtctaaag
     8761 tgtaggtgta ttttttgaga ttggttttcg gcgttttgtc aacaacggtt acaccgtcct
     8821 caatgctgtc gcagattacc tgaatttcgg aaacaggatt ctgcttttcg cttttgaagt
     8881 tgagaagttt tgtcgcaaaa ttaaagctta catcctcaaa gccgtctgtt tctgcaattt
     8941 tagcctcaat cttgcccgca caatgagcac aattgagatt gtctaaagtg taggtgtatt
     9001 ttttgagatt ggttttcgga gttttgtcaa caacggttac accgtcctca atgctgtcgc
     9061 aaattgcctg actctcggaa acaggattct gtgtttcgct tttgaagttg agaagctttg
     9121 tcgcaaaatt aaagcttaca tcttcaaagc cgtctgtttc tgcaatttta gcctcaattt
     9181 tgcctgcaca atgagcgcag ttgagattgt caagctgata tttgtacctc atatgtttgc
     9241 ctccttattc aagaacatgg tcaagtccca tttctatgat tcgtttcaca tggtcatcgt
     9301 caaggctgta ataaatctgc tttccttcac ggcgaacacg caccagcttg ttctgcctta
     9361 acacacgcag ttggtgggaa attgtgcttt gctccatgct gagagcttca gcaatgttga
     9421 gcaccgacat ttcattttcc gaaatggtgt acataatgcg aagtcgggtt gaatcaccga
     9481 aaaccttaaa aaggtctgca agctcaaaca gcacatcaat gtcgggcatt tcgggagtgg
     9541 ttgttttttc tttgttttcc ataggcgtcc cctttaattt tctctcaggt taaaagttat
     9601 acttgaacat atgaagatat gctcatatgt taattataat atagcattcc atttttaaaa
     9661 agtcaataga catagaggga aaagtgtaat atttttttga ttttttacaa aaaaacagcg
     9721 gcaaaagcat ttgctttcac cgctgtgagt acagaatatt ttgttttatg ccattccgaa
     9781 ataactgaga atattgaatc ctgtcggcat cggaattgta aacatatata tagtggcaag
     9841 aataaaacct gcaactgcaa caccgagcac aattcttctg ttcggaagat tcttgaatgt
     9901 gcctacgata ccgagcataa agagtacaac cgagtaaatt acgcttacaa gaccgaatgc
     9961 gtcaccgttt gcgttatctt tcttaccttg ttcaagaagt ttgtccgact cttcaattgt
    10021 agcttgtgcc tctgcaaaat aactttcggt gtaaccgtcc ttcataaacg gagttacatt
    10081 ttccttttga tccattgccc aattaattgc ctcaagaaat tcttctgtac agttatcact
    10141 cataagctga tcaatttggt actgatattt ttccatttcc gctttatcgt ttttagattc
    10201 cgcatattgg taattaaggt ttgcctcatt gatgtcattc catgtgatca tatcctgcat
    10261 aagattttga gaagcctcat tccacatcga gttgccctct gatgagaggt tgttgctttt
    10321 tgtgtagtta gtcgcctgat ttccgccgtg aagtgaacct atccacgatg cccatgctgt
    10381 ggcgagtgcg gttattccga gaaaaatcgc aacaataatt tcaatttttt cttcactgct
    10441 tcttttactt atttttttcg gttcttttgc tgtttcgctc attctgaatc ccccgttaat
    10501 taaaaatttg tcgcaatgcc ttaattttgt cattattata atgtaaaagg acacttgccg
    10561 actgattctg tttcaatcat aattgataaa agttttaaat tcaatgcaag tggcagtaaa
    10621 gtcttttttt cggcataata atcattttgt ctgtgatttt ttaaaaattt acctttagat
    10681 atttttgttt tattcgtttg atttgcaaag aataaatata tacgatagat ttgcctgcaa
    10741 attttcaatt aagaaaatat aataactgtt tcaatttgta attattttac aaaaaattgc
    10801 tttgattaat tacttctttt taggaaaaaa cgattttaaa aagtatggtt ggttatatta
    10861 aaaacaaaaa aagcaacaaa ttaataattt gagtacaact tgcccaaaaa tagattacag
    10921 ttttattatt ccgttgactt tactacaatt ttgtagtatc attttctgta agagaattgt
    10981 taaattacat ctgcgtaacc gagtgggttc gtttttaata aaatgtaaca aattagttct
    11041 cattatgaat tttagattcg tataattttt gatttttact tatacactat atagatatac
    11101 attttcagat atttagctta tttagttaaa agtatcttct acacattaat tggggtgtaa
    11161 caattggaga agttcgtagt taccggcgga aagccattat cgggtgaagt gacaatcagc
    11221 ggtgcgaaaa atgcagctgt tgcaattatt ccggcagtta ttctttgtga tgaaccgtgt
    11281 cagattgaaa atattcctaa catcagcgat gtatcactta tcagcagaat tcttcagcag
    11341 atgggtgcta atgtaagacg aatcaaccgt tcgtccttat atattgatcc tacaaaaatc
    11401 cgcacatgca atgctgtgac cgaccttgta agaggtatga gagcgtcata ttatcttctc
    11461 ggcgcacttt tgggcaagta cggcaaggct aaggtggctc ttccgggcgg ctgtaacttt
    11521 ggcgtgcgtc cgattgacca gcatcttaaa ggctttgagg ctctcggtgc gacaactcag
    11581 cttgttgacg gtgcgattat agaggcagaa tgcgacaacc ttgtcggtac acatgtgtac
    11641 cttgatgttg tgtccgttgg tgcaacaatg aacattatgc ttgccgcatc aaaggcaaag
    11701 ggacagacca ttattgaaaa tgccgcaaga gaaccgcata ttgttgacct tgcgaacttc
    11761 cttaattcaa tgggtgcgga tgtcagaggt gcaggtacgg atgtcatcaa aatccgtggc
    11821 gttgagtatc ttcacggcat tacttattcg attattcccg accagattga ggcaggaaca
    11881 tatatgtgtg ccgccgccgc aacaagaggt tgtattacgg taaagaatat tacaccgaag
    11941 catcttgaat caatcagcgc aaagctgcgt gagatgggtg ttaagattac ggaatatgat
    12001 gaggctctca aggttgatgc gtcatctgct ccgctaaagc gctgtaacat caagacaatg
    12061 ccgcatcccg gcttcccgac agactgtcag ccgcagtttg ccgcattgct tatgagcgtt
    12121 cccggaacaa gcatcatcaa cgagaatgtt tgggataatc gctatcagta tgtcagcgag
    12181 cttatcagaa tgggtgcgca gatttctgtt gagggcagac ttgcaatcat tgagggcggt
    12241 gttccgctca cagcggctcc cgttaaggca accgaccttc gtgcaggtgc ggctatgatt
    12301 attgccgctc ttgaaattaa cggtacaaca gagatttcaa atattcagtt cattgagcgt
    12361 ggatatgaag atgttgttga aaagttcaga gcactcggtg cagatatcaa aaaggtgtat
    12421 tttacaggag acaacgagca ggagctcggt gcctgactaa aatttaatta gaaatcaaag
    12481 ccgttttctt tgtgagaacg gcttttttgt gagataattt acaaatttta aaatttgtgt
    12541 tatcatattc gttatactaa agataaggat tgattgtttt ggcaagagca gtaccgctgt
    12601 tcagcggaag taagggtaac agctactaca taggttcggc aagcgaaggc gtactgattg
    12661 acgcaggtcg ttcatgcaag cagattgaaa atgccatgct tgcaaacgga cttgatatgg
    12721 gcagtatcgg ggcggttttt ataactcacg aacacactga ccattgcagt gcgttgcgtg
    12781 tgcttgcaaa gcgttacggc tttaaggtgt attcaagcct tggtacgctc aatgctttga
    12841 gggcaggtaa taagcttgat ccaaacacag atgcagatgt tataactgac gaggttgtaa
    12901 tcggcaatat gcgtgttcag cgaattgaca ccccccacga tgcggcggaa agctgttgct
    12961 accgtgttac tgctcccgac ggaaaatccg cacttatagc aaccgatatg ggcgttatgt
    13021 tgcccgatgt cagaactgcc gcagagcaga gcgactttgt tgtgcttgag tcaaatcacg
    13081 atattaatat gctcaaaaac ggattttatc cttatccgct aaagcagaga atcctttcaa
    13141 acagaggaca tctttcaaat gaggcttgtg caaaagaact tgttaacctt gttgaaaagg
    13201 gaactttaag gcttatgctc ggccatctca gcgaagaaaa taataccgtt ccgcttgcaa
    13261 tgtcaacatc cgtagacctg ctcacatcaa acggaatgaa gtacaaaagc gattattcgc
    13321 ttgatgttgc tccgagtgta agcacaacaa aagccatcat cttttaacct taaacaaaca
    13381 agaggaatat gattaagatt aacataattt gtatcggcaa aatcaaggaa aaatatttta
    13441 ccgacgcaat tgcagagtat gcaaaacgct tgaccgcatt ttgtaaattc aatattattg
    13501 agctttcgga agaacgcatt aagaacaaca taccgaatag gtcgcagatt gatgaggtta
    13561 ttttctctga gggaaaacga atcatgcaga aaatttcgcc ttcggattat gttgttgcaa
    13621 tgtgtattga gggaaagtct atgtcgagtg aggagctttc aaagctgatt gacaatgcgt
    13681 ccgtaagcgg aaaaagcacc gttgatttta ttatcggcgg cagctacggg cttgacgaat
    13741 cggttaaaaa acgggcagat gtccgtcttt caatgagcag aatgaccttc cctcaccaaa
    13801 tggcaagaat gattttaagc gaacagattt accgtgcgtt tgagatttca tcaaacggta
    13861 aatatcacaa ataatttacg gagttactat ggcgcttgac ggaatttttt taagacatat
    13921 taaaagtgaa atagaaaaag aggctctcgg tgcaagggtg tcgcagattt atcagccgaa
    13981 cagagaggag cttgtgttcg ggctgagaac attttccggc aacaaaaagc tgttgctttc
    14041 tgcacgagca aattcaccga gagtgaactt ttgttcctca acacccgaaa atcctgcaca
    14101 acctccgatg ttctgtatgc ttttgcgaaa aagaatcggc ggcggaaagc ttgtgggact
    14161 tcgccagaac ggttgcgacc gtgttcttat gctcgatttc gagtgcgtga acgaactcgg
    14221 cgatactgtg atgataactg ttgtatgcga aattatgggt atgtacagca acataattat
    14281 tgttgattca aacggtgtta tcatcgactc gctcaagcgt gtagatctta caatgagcag
    14341 taaaaggctt gtactgccga atataaaata cgaacttccc gaatcgcaga acaagctgaa
    14401 tctgcttaaa tgttcggtgc ttgatgtgtg tacagccgta aaaaatcttg acacggaaat
    14461 gccgcttaac aaggcgctgt taaggacaat tgagggtgtt tctccgattg tatgccgtga
    14521 gattgaatac aaggttatgg agggcgcaac aaacagaatt gagggtgtgc tttttgaccg
    14581 actcgcagtt gaaattgaaa agctgaaaag cgtttgcagt gattgttcgg gcaagcctgt
    14641 tgtggtttat cgtgaggacg gcaagcctat ggacttctgc tttatgaatg ttgagcagta
    14701 cggcgatttt gcaaaggttg agagtaagga aagcttctcc gatttgcttg acggattcta
    14761 tgaggctcgt gacagtcgtg acagaatgag ggtgaaatcg caaagcctta caaagctttt
    14821 gaacaacaca cttgaaaggc ttgcacgaaa aattgcaaag cagaagagtg agcttgaacg
    14881 ctgtgcagac cgtgagcatc ttcgcatatg cggtgacctt ttacaggcaa atatctatcg
    14941 cattgagcgt ggtgcggagt atgttgatgt tgaaaacttt tacgatgaga acaacgcaat
    15001 tttacgcata aagcttaatc cggcaatctc acc
//
