LOCUS       gnlProkkaLFAOFDKJ_43    8395 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LFAOFDKJ_43.
ACCESSION   gnlProkkaLFAOFDKJ_43
VERSION     gnlProkkaLFAOFDKJ_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:19:12
            Original ID  :: gnl|Prokka|LFAOFDKJ_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8395
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8395
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5734:7481]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5735..7481
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..8395
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8395
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(3..233)
                     /locus_tag="ctg43_1"
                     /transl_table=11
                     /translation="MAYFYEEPSRTFGEYLLVPGYSSAENVPTAVSLKTPLVKYRKGQE
                     ECPLQMNIPMISAIMQSVSGDKLAIALARQGG"
     CDS             852..1652
                     /locus_tag="ctg43_2"
                     /transl_table=11
                     /translation="MKTKLGIVGCGFLGIIVADAWKKGLLPDYELVGVTSRTRASAEKT
                     AANVGCAVCEDVDALLALEPEYIVEAASVESVRAMAIPVLKRGVNLVILSIGAFADLDF
                     YAQVKAAAVEGGAKVHLASGAIGGFDVLQTVTLMAQAQGLPETAGIETHTGAKGFRNTP
                     VWAEHLLTDTEKTTVFTGNAKQAIATFPRRVNVAVATSLATTGPEITGVTMHSVPGWVG
                     DDHCITAEIEGVKAVVDICSSTSAIAGWSAVSLLRNLSSPVCFY"
     CDS             1671..2567
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 97; E-value: 1.5e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_3"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 3.1e-18, bitscore:
                     55.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEKLVAIEPVSLIPSAEEELHRYAKEVVLYRDVPGSDAEMVRRI
                     GDADAVLLSYTSRMGKEVIAQCPNIRYIGMCCSLYSEESANVDIAYARTRGIQVLGIRD
                     YGDRGVVEYVLHELTGLLHGFGMPMLRDEPVEITGLKVGIVGLGVSGRMIADALQFMGA
                     EISYFARSAKPDAEAVGMTFKPLAQLLAESEVVFTCLNKNVLLLGENEFAQLGAGKVLF
                     NTSIGPGFDSAALEKWLDLPGTRFFCDTRAAAGPVAEDFFARENVRCANVSAGRTKQAF
                     VLLSKKVLDNIRTALGE"
     CDS             2788..3588
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MKTALTIAGSDSSGGAGIQADIKTMTANGVFAMSAITALTAQNTT
                     GVTAIFDTTPQFLAQQLDAVFTDIYPDAVKIGMVSSAPLIDTIAERLHFYGAKHIVVDP
                     VMVATSGAKLLQDDAVQALTEKLLPLAEVLTPNIPEAEILAGMSIANAADMEAAARTIS
                     ERYGCAVLCKGGHQINDADDLLWQGGTGKWFKGKRIANPNTHGTGCTLSSAIASNLAKG
                     YDLDTAVERAKAYISGCLSAMLDLGHGSGPMDHTFNLKGDFVRD"
     CDS             3581..4258
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MTDLPFVSALVQADLPVWEQCLQTEFLQKMENGTLSEDCFKSYLV
                     EDSLYLREYAKIFAWGMTKATTMAAMRTYYSLLSFVQENEDLTRLRYLEQYGLREADIQ
                     SLPLRPENRAYLDCMIDAARTGEGEAECLMACLPCMLSYGWLFQKLLQRSPAVKDTYYG
                     ALVLDYAGPGYDAACRAWAERAEAACTGLSPERAARCRAIFRACSEHELHFWEMCATPR
                     TDI"
     CDS             complement(4320..5738)
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MSMTTPIVDFVRSYAKSGTARLHMPGHKGQSLLGFEPLDITEICG
                     ADELYAPEGIIAESEANATRLFGTVHSYYSTEGSSQCIRAMLFLALQGAPQNGKRPVLL
                     AARNAHKALLYAAALLDFDIRWLWPSAQAEGALCSCPVTAEALTGALHAMAQQGNTPFG
                     VYVTSPDYLGGVQDIPALAAVCRAQGVPLLVDNAHGAYLRFLPQNCHPIAQGAAMCCDS
                     AHKTLPVVTGGAYLHLAHDAPVQDEAAVRGALALFGSTSPSYLILQSLDACNAVLAGDY
                     PRRLVQCCAALEGLRRSLNKAAAARQCPVPLAVAGAQQEPMKLTLDAAALGCTGTALAD
                     ALRRAQLECEYADPRYVVLMFTPENPPQDYTRLQATMEQLLAAVPAGLPRPENRAGEFA
                     ALQQQAVQRCTIRQAVLGAQVRIPVHKALGRVCAMPTVSCPPAIPVAVSGEEITPAAIA
                     LMQRYGIEELSVLR"
     CDS             complement(5735..7186)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_7"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.9e-31,
                     bitscore: 97.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.7e-16, bitscore: 48.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.6e-17, bitscore: 52.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8e-21, bitscore: 63.6,
                     seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFDMVKKLVAYCREQEKIHNKNFRFTMTTNGVLIDDDVIDFCNKECHNVVLSLDGRKEV
                     NDRFRVDCAGNGSYDRIVPKFQEFVKKRGDKNYYMRGTYTHYNTDFTNDIFHMADLGFT
                     ELSMEPVVCDPSDPSALTEADLPILKEQYEILAKEMIKRDREGRGFTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDPKYLLGDIWKGVTNTAVRDEFKHCNA
                     YARKECQDCWAKLYCSGGCAANSYHATGSITGVYEYGCELFKKRMECAIMIKVAENQEL
                     AAKGIEVPIELGSTCNACADGEACE"
     CDS             complement(7254..7481)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_8"
                     /sec_met_domain="TIGR03973 (E-value: 3.7e-26, bitscore:
                     80.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.1e-25, bitscore: 77.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISYYKIKAYRNYVRRDKILRVREVSIMERIKTIATRDLTKSVKT
                     GGCGECQTSCQSACKTSCGVANQQCENSNK"
     CDS             complement(7697..7984)
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRVPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGG"
ORIGIN
        1 acgccgccct gacgagccag tgcaatggcc agcttatcgc cggagaccga ctgcatgatg
       61 gcgctgatca tggggatatt catctgcagc gggcactcct cctgtccctt gcggtacttg
      121 accagcgggg tcttcaggct gaccgccgtg ggcacattct ccgcagagga atagccgggg
      181 accagcaggt actcgccaaa ggtgcgggag ggttcttcgt agaaataagc cataatcaaa
      241 ctccttttct cttagggtgt atctgataca aatcagcatc aaaatcattc atgtttgctg
      301 cttataaatt gattgtatat actttaccac aaagcccgca agaatacaaa cccctgccgc
      361 gccaaacttt ataattgtcc tttgcggaaa aacagacaaa ttgacaagcg tttttaggca
      421 ttggtcatac tttggttttt gaagtatcac ttttacgggc aaaacagggc ttgcagaatg
      481 caaaaaagct cgtccgaaac accggacgag cccttttgca cacgaagcgg gacactgcct
      541 gtgcggcgca tgggtcatag ctgtgaagga gaacagccgg aggaggagga cccgcgccca
      601 gtatcccaaa aacaagaaga aaaagatttc acacacagcc ttggggcttt gcccttgctg
      661 taaccatatt gtaactcttt tgaaaccatt ttgcaatagg gttttgtaat ttttttgtaa
      721 tttattttgt taacttttta tgtcctgccc cgccgggctg ccgcaaacat tatttccctt
      781 tttgtacccg gtatggtata ctggctatga atatgctgcc acaggcagaa aaaaggagtt
      841 taggatacgg tatgaaaaca aaattgggta ttgtgggctg cggatttctg ggcatcatcg
      901 tggctgacgc gtggaagaag ggtctgctgc cggactacga gctggtgggc gtgaccagcc
      961 gcacccgcgc ttcggctgaa aagaccgccg ccaatgtcgg ctgcgccgtc tgtgaggacg
     1021 tggacgcact gctggcactt gagccggagt acatcgtgga ggcggcctcg gtggagtcgg
     1081 tgcgcgctat ggccatcccg gtgctgaagc ggggcgtcaa tctggtcatt ctgtccatcg
     1141 gtgcctttgc ggatctggat ttctacgcac aggtcaaggc agccgccgtg gagggcggtg
     1201 ccaaggtgca cctggccagc ggtgccatcg gcggctttga cgtgctgcaa actgtcaccc
     1261 tgatggcaca ggcgcagggt ttgccggaga ctgccggcat cgagacccat accggtgcaa
     1321 agggcttccg caacaccccg gtgtgggcag agcatctgct gaccgacacc gaaaagacca
     1381 ccgtgttcac cggcaatgcc aagcaggcca ttgccacctt cccccgccgg gtgaacgtgg
     1441 cggtagctac ctctctggcc accaccggcc ccgagatcac cggcgtgacc atgcactccg
     1501 tgcccggctg ggtgggcgat gaccactgca tcactgccga gatcgagggc gtgaaggctg
     1561 tggtagatat ctgctcttcc accagcgcca ttgcgggctg gagcgccgtc tctctgctgc
     1621 gcaatctgtc ctcacccgtc tgcttctact aatataagga ggagtccgtc atgtttgaaa
     1681 agcttgttgc cattgagcct gtcagcctga tcccctctgc cgaggaggaa ctgcaccgct
     1741 acgccaaaga ggtggtgctg taccgggacg tgcccggcag cgacgccgag atggtgcgcc
     1801 gcatcgggga cgccgacgcc gtgctgctga gctacacctc ccgcatgggc aaggaagtca
     1861 ttgcgcagtg ccccaacatc cgctatatcg gcatgtgctg cagcctgtac tctgaggaga
     1921 gcgccaacgt ggatattgcc tacgcacgca cccggggcat tcaggtgctg ggcatccggg
     1981 attacggcga ccgcggcgtt gtggagtatg ttctgcacga gctgaccggt ctgttgcacg
     2041 gctttgggat gcctatgctg cgggacgagc cggtggagat caccggcctg aaggtgggca
     2101 tcgtggggct gggcgtttcc ggccggatga tcgccgatgc gctgcaattt atgggcgcag
     2161 agatcagcta ctttgcccgc agcgcaaagc cggatgccga ggctgtcggt atgaccttta
     2221 agccgctggc tcagctgctg gctgagagcg aggtggtgtt cacctgcctg aacaagaacg
     2281 tactgctgct gggcgaaaat gagtttgccc agctgggtgc aggcaaggta ctgttcaaca
     2341 cttccatcgg ccccggcttt gactccgctg cgctggaaaa gtggctcgat ctgcccggca
     2401 cccgcttctt ctgcgacacc cgcgccgctg caggccccgt ggccgaggac ttctttgccc
     2461 gggaaaacgt gcgctgcgcc aatgtatccg caggccgcac caagcaggcc tttgtgctgc
     2521 tgagcaaaaa ggtactggac aacatccgca ctgcactggg cgaataagcg gtgcgtttgc
     2581 gcggcctgtt tttcttgcat cttttccccg attgtggtat gctttctagt ataaaaaggg
     2641 agcccgtgca agcgggctga gagtgggctg tattgccctg acctgtgacc tgatttggat
     2701 catgccaacg tagggagata gcgcttttat ctgcggatat gtctttgcgg gcatatccgc
     2761 atttttgctg caaaggagca tttacccatg aaaactgcat tgaccattgc cggcagtgat
     2821 tccagcggcg gcgccggaat tcaggccgat atcaagacca tgaccgccaa cggcgtgttt
     2881 gccatgagcg ccatcaccgc cctgacggca caaaacacca ccggcgtgac cgccattttt
     2941 gacaccacac cgcagtttct ggcacagcag ctcgatgccg tgttcaccga catttacccg
     3001 gatgcggtaa aaatcggtat ggtatcctct gccccgctca tcgacaccat cgccgagcgg
     3061 ctgcattttt acggcgcaaa gcacattgtg gtggaccctg tgatggtggc cacctccggt
     3121 gcaaagctgc tgcaggacga tgccgtgcag gcgctgaccg aaaagctgct gccgctggcc
     3181 gaggtgctta cccccaacat cccggaggct gagatcttag ccggcatgag cattgccaat
     3241 gccgccgaca tggaagccgc tgcccgtacc atcagcgagc gctacggctg tgccgtgctg
     3301 tgtaagggcg gccaccagat caacgatgct gacgacctgc tgtggcaggg cggcaccggc
     3361 aagtggttca agggcaagcg cattgcaaac cccaacaccc acggcaccgg ctgcaccctg
     3421 tccagcgcca ttgcttccaa tctggccaag gggtatgacc ttgacaccgc cgtggagcgc
     3481 gccaaggcct acatttccgg ctgtctgtct gccatgctgg acttagggca tggctccggg
     3541 cccatggatc acaccttcaa cctgaaggga gattttgtcc gtgactgacc tgccctttgt
     3601 ctcggcgctg gtacaggccg acctgcctgt gtgggagcag tgtttgcaga ccgagttttt
     3661 gcaaaagatg gaaaacggca ccctgagcga ggactgcttt aaaagctacc ttgtggagga
     3721 cagcctgtat ctgcgggagt acgccaaaat ttttgcgtgg ggcatgacca aggccaccac
     3781 catggctgcc atgcgcacct actattccct gctgtccttt gtgcaggaga acgaggacct
     3841 gacccggctg cggtatctgg agcagtacgg tctgcgggaa gccgatatcc aatccctgcc
     3901 cctgcggccg gagaaccgcg cctatctgga ctgcatgatt gatgctgccc gcaccggcga
     3961 gggggaagct gagtgcctga tggcctgcct gccctgtatg ctgagttatg ggtggctatt
     4021 ccagaagctt ttgcagcgct cccccgccgt aaaggacacc tactacggcg cactggtgct
     4081 ggactacgcc ggccccggct atgatgccgc ctgccgcgca tgggcagaac gcgctgaagc
     4141 agcctgcacc ggcctttcgc cggagcgtgc cgcccgctgc cgcgcgatct tccgcgcctg
     4201 ctcggagcac gagctgcact tctgggagat gtgtgcaaca ccccggacgg atatttaaga
     4261 ataaatatag agaacccgga agttccgcag accttccggg ttctcttctt ataaaatctt
     4321 tatcgcagca ccgagagttc ctcgatgccg tagcgctgca tcagggcgat agccgccggg
     4381 gtgatctcct cgccgctgac cgccacaggg atggcgggcg ggcaggacac cgtaggcatg
     4441 gcgcacaccc gccccagcgc cttgtgtacc gggatgcgca cctgtgcgcc cagcaccgcc
     4501 tgccggatgg tacagcgctg caccgcctgc tgctgcaagg cggcaaactc tcctgcccgg
     4561 ttctcggggc ggggcagccc ggcaggcaca gcagccaaaa gctgttccat cgtagcttgc
     4621 aggcgcgtgt agtcctgcgg cgggttttcc ggggtgaaca tcagcaccac ataacggggg
     4681 tctgcatact cgcactccag ctgtgcgcgg cgcaaagcat ctgccagcgc tgtgccggtg
     4741 cagccaaggg cggcggcgtc cagcgtaagc ttcatcggct cctgctgtgc cccggcaact
     4801 gccagcggca ccgggcactg ccgcgccgct gcggccttat tcaggctgcg gcgcagacct
     4861 tccagcgccg cgcagcactg caccagccgc cgggggtagt cccctgccag caccgcattg
     4921 caggcatcca gcgactgcaa aatgaggtaa gaggggctgg tagagccgaa cagcgccagc
     4981 gccccccgca cagccgcttc gtcctgcaca ggggcatcgt gcgccagatg cagatacgcg
     5041 ccgccggtga ccaccggcag ggtcttgtgg gcagagtcgc agcacatggc cgcgccctgc
     5101 gcgatggggt ggcagttttg cggcagaaag cgcaggtagg ccccgtgggc gttatccacc
     5161 agcaaaggca cgccctgcgc ccggcagaca gcggccagcg ccggaatatc ctgtactccg
     5221 cccagataat ccgggctggt gacgtatacg ccaaaggggg tgttcccctg ctgtgccatc
     5281 gcgtgcaaag cccctgtcag cgcttcggct gtgacggggc agctgcacag tgcaccctct
     5341 gcctgcgcag acggccaaag ccatcggatg tcaaaatcca gcagcgccgc cgcgtacagc
     5401 agcgccttgt gggcattgcg ggcggccagc agcaccgggc gcttaccgtt ttgcggtgcg
     5461 ccttgcagcg ccagaaacag catggcacgg atgcactgag acgagccctc agtgctgtaa
     5521 tagctgtgca ccgtgccgaa cagccgggtg gcgttggctt cactctcggc aataatgccc
     5581 tccggcgcgt aaagctcgtc tgcgccgcag atctcggtga tatccagcgg ctcaaagcct
     5641 aaaaggctct gccccttgtg gccgggcatg tgcagccggg cggtgccgga ctttgcatag
     5701 ctgcgcacaa aatccacgat gggggtggtc atgctcattc gcaggcttcg ccgtcagcgc
     5761 aggcgttgca ggtagagccc agctcaatgg gcacctcaat acccttagca gccagttcct
     5821 gattctcggc taccttgatc atgatggcgc actccatgcg ctttttgaac agctcgcagc
     5881 cgtactcgta cacgccggta atgctgccgg tggcgtggta ggagttggca gcgcagccgc
     5941 cggagcagta cagctttgcc cagcagtcct gacactcctt gcgggcgtag gcgttgcagt
     6001 gcttgaactc atcccgcaca gcggtgttgg taacgccctt ccagatatcg cccagcaggt
     6061 acttggggtc acccacgaac tggtggcagg ggtacagatc gccccaaggg gtaacagcca
     6121 tgtactcggt gccggagccg cagccggaga tgcgcttata gatgcagggg ccgccggtca
     6181 ggtcgatcat gtagtggtag aaggtaaagc ctctgccctc gcggtcgcgc ttgatcatct
     6241 ccttggcaag gatctcgtac tgctccttca ggatgggcag gtcggcctca gtcaaggcgc
     6301 tggggtcgct ggggtcgcag accaccggct ccatgctcag ctcggtaaag ccgaggtctg
     6361 ccatgtggaa gatatcgttg gtaaagtcgg tgttatagtg ggtataggtg ccgcgcatat
     6421 agtagttctt gtcgccgcgc ttcttgacga actcctggaa cttgggcacg atgcggtcgt
     6481 agctgccgtt gcctgcgcag tccacgcgga agcggtcgtt gacctccttg cggccatcca
     6541 gactcagcac cacattgtgg cactccttat tgcagaagtc gatgacgtcg tcatcaatga
     6601 gcacaccgtt ggtggtcatg gtaaagcgga agttcttgtt atggatcttc tcctgctcgc
     6661 ggcagtaggc caccagcttt ttgaccatat caaagttcat cagcggctcg ccgccaaaga
     6721 agtccacttc cagattgcgg cgggtgccgc tgttctcgat gaggaagtcc atggcgcgct
     6781 tgcccacctc aaagctcatc agggcgcggt cgccatggta gcgtccctgc gaggcaaagc
     6841 agtaagagca gctcaggttg cagctatggg caacgtgcag gcacagcgcc tttaccacag
     6901 tgttgcggtt tttaaagtcg aaggccatgt ccttatagac atccgggctc cacagcttgc
     6961 cgttttcctt caggctggtc acgtcgtcga tgcactggcg cagatcctcc tcggtcacgt
     7021 ccgggcggct gccgtacttt gccagcatgg cggcaacgat ctcgtctgcg gtatgctccg
     7081 ggtacatggc gatgacatcg taggccacct cgtccacaac gtgcaccgag ccgctgcagg
     7141 tgtccagcac gatgttataa ccgttcaatt gatactgatg taccatttta cactccattc
     7201 cagattacac aaaaaaatgc cgcccggcaa aggcggcata gggtttgcaa aaattacttg
     7261 ttgctgttct cgcactgctg gttagccacg ccgcaggagg tcttgcaggc ggactggcag
     7321 gaagtctggc actcgccgca gccaccggtc ttaacgctct tggtcaggtc acgagtagca
     7381 atagtcttaa tacgctccat gatagaaacc tctctaactc tcaaaatttt atcgcgccgg
     7441 acatagttcc ggtacgcttt tatcttgtaa taggatatca cgcagcgcgc cttttgtcaa
     7501 gattttttcg ctaaggcaat accgcataat tctaggtgcc gatacggcga gtgaggtgcg
     7561 gcagatgcta agccaaaagc gcagataata ctttgtgtat tatcgagcat tttggcaacg
     7621 cagatgccgt gccgcaaccg ccggagtggt gcttaagccg taaggcggga attgtgcggt
     7681 gttgccctaa gcctttttac ccgcccatgg gctggtagcg ggtaagcacc gtatgcagcc
     7741 ccagctcccg ggcgcgcgcc agtaagtacc ggtagcggca caaaagcgcc tgccgctcgt
     7801 agatgcgctg ctcgatgagg tccgtatcca cctccatatc aaacatcatc tcgttgcgct
     7861 tcaaacagaa caggcattcc ttcagttcct cctccagctc cgggtggtag cgctcgtgct
     7921 cggtatcccg cgggacgcgg ggcgaaagca gggtctgggc gttttgtgtg gttcgttccg
     7981 gcataggcat cctccttctg gtactttgca aggttttgta ccttccagta taggcggtgc
     8041 ggtgcgcaga acctgccgaa gtgtggcagc gctccggcat agattatccg gcgctgctgc
     8101 ggcattttcc aaaaaagtac aacttttttc aaaaatatgc ttgacaactc cgggcttttc
     8161 ccgtataata gcacacgttg agcggctcac cccgcaaaac acaacagaat attggggatt
     8221 tgcatagtgg tagtgcggta gactctgact ctacttgtgg gagttcgatt ctctcatccc
     8281 caaccagatt aaagccatct gaagaagttc aggtggcttt tctgtttata tcattccgaa
     8341 ccacagccgc aaggccgtga ctcttcaaca cttgaagagt cataactcta ttacc
//
