LOCUS       gnlProkkaMDNPHBBN_80   12970 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDNPHBBN_80.
ACCESSION   gnlProkkaMDNPHBBN_80
VERSION     gnlProkkaMDNPHBBN_80
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 15:24:47
            Original ID  :: gnl|Prokka|MDNPHBBN_80
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12970
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12970
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2382:2970]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2383..2970
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..12970
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12970
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(237..1505)
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="MLYYFVEFAGSFANIALLLLFIGRLFPKKEPVSRWFYASYVALLI
                     AGQCALSLFPDWVTQRTIYLLVGGFLLALLFYEVRPWQAVFASGAFFTLAALVEVLAML
                     LIGLRIPDTDILMQAGAARLVYIVFSNLIQIPLVVLISHFFSRKGNALRILWLLPIIAI
                     QIASIAVCYVAQYHAADDYYPDYMVGLMAVLLLINILIVFYVEALRENELEKFKVKFNE
                     QQYNLQMEYYQQLKERQEEVRSLQHDVKKYILAMQAVAEHGDTEELHKIAQAATNVFER
                     STNISAVGNPVVDALLNYYLRIAERNNIKVKLDVTIPEVLTISSLSLSIIIGNTFDNAI
                     EACCDLPAEQRIIHLQLRKQYRSLFYRLENPYSDTVRSIRIGEYHGYGLKNINRIVQEN
                     HGDFYTKKKDGVFTVQVRLNCEN"
     CDS             complement(1505..2203)
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MLKYHVAVCDDEKSDLDGIVQSVQQYDVQGCFDIETYMDGNELLS
                     ELQMQKKSFDLLLLDIEMPSNGFQLAQSLIQMEKHPLVVFVTKRHEYAVQGYGVAFRYL
                     VKPLDQTLFAAAMDAVLQELNSKHFTIEYDGITMSLETSDIYFLESHGHKVLIHCKEQD
                     LTLRMSIPEALEQLPKRCFVSPHKSYLVNMEHIVYATGTAVFLSSGHQLPISRRKRQEF
                     NQIFNAYLGR"
     CDS             2383..2970
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_3"
                     /sec_met_domain="AgrB (E-value: 1.5e-36, bitscore: 115.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWERTLSQKLVRLFCEQKVIDEAKADAYVYGYELLISSVVSVLLV
                     VLIAVVCGDVRYALSFLIGFIPQRIYIGGYHATSHTRCYLAFSGLALICILLSKAIAAN
                     HLFRILTTVALLGISIFLSPIEAKNKPLSEKKRSSYKMVASVLSSIDFLLAIFNVLPYT
                     RHVVCYYLSKWVLIVFSTIPLVQQKFNANFCR"
     CDS             2983..3153
                     /locus_tag="ctg80_4"
                     /transl_table=11
                     /translation="MKKNKWVLLLIAFVAFLVLIYFIGACLNATAEALTIISLCIGILV
                     IYLVVKAIKSK"
     CDS             3171..3311
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MKFSVPEILMIILTTAVVIIAFLALAKYLIRYAVKFYIKIKGDDL
                     K"
     CDS             3308..3841
                     /locus_tag="ctg80_6"
                     /transl_table=11
                     /translation="MTLRKRLISLCMVMVLVFSLSAVCASAAQEAVAEQPTVSMSFDLD
                     NRVKHEKTVRLPDGSIAKITAEPINTGRALSGVWKITGTNGLATMEYWIELEKAGLYTK
                     IKRTWGLAITGIMTSYEDAKINVVRQMESPVLPAVVEGYAKFTYFDNPVVTLWTKSGGV
                     RASISGNQITTELY"
     CDS             4063..5622
                     /locus_tag="ctg80_7"
                     /transl_table=11
                     /translation="MTAVIYARYSSDNQREESIEGQIRECTAYAEKNDITIVKHYIDRA
                     ISAKTDNRPQFQQMIKDSDKKLFDIVLVWKLDRFARNRYDSARYKTQLKKNGVKLMSAT
                     EIISEGPEGIILESVLEGYAEYYSADLAEKVVRGQTENILKGRCNGGRGTFGYTLDSER
                     KFHIDPLASPFVLESFRKYRDGLTMKEIRDWLNENGIKNPVGGEFTYNSVEHMLKNRRY
                     IGELKFRDVVVPDAIPPIIPLELFEDVQEKIAKNKKAPARRKAEDDYLLTTKLYCGYCG
                     ALMFGESGTSRTGEVHRYYKCATAKKKKGCKKKTVRKQWLEDLVVNQTMQLVRDDAAME
                     SIIAKVMELQDRENTNLPLYEKQLRDAESGIQNMLNAIQAGILTSSTKERLEQLEETKR
                     ELEAHIAEEKLAKPKIKEEFIRFWLMRFRKLDMSLKDQRQALVDTFINSIYLYDDKVLI
                     TFNYKEGTQTITFEEAAQAASKENGSDLDCFTAPRTAAQVMCSSPFYYFIESILQKRHS
                     AL"
     CDS             5686..7047
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 285.6; E-value: 1e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MASQTNTLTEGPLAKQIFLVSLPLALSNLLQVLFNMSDVAVVGRF
                     AGSTALGAVGSTSTLVTLFTGFLIGLSNGINVLVARFYGARHPKDVEKTVHSAAIISAV
                     AGVALLLIGLLGSPAMLRLLNTKEDLLPGAILYLRVYFLGMPALALYNFGNAVFSSIGD
                     TKKPLMYLSIAGALNILLNLFFVIVCNLSVVGVALASAISQCVSAFLILRALTRVQDCY
                     ALDPHKLQLDPVQAKSILALGVPAGLQNAIFAIANLFIQAGVNSFDSLMVKGNSAAANA
                     DGLIYDCMAAFYMACASFMSQNYGAGRPDRVKKSYFISLGYSFGVGFVLGAALFFCGPA
                     FLALFTTEAAVIDAGMKRVAVMAFAYGISAFMDCTIAASRGLGKTVIPTVIVVLGSCVF
                     RVIWVYTIFAHFHTIPALYLLYPCSWILTALAEIAYFASCYKRAMAIFRKPAAA"
     CDS             complement(7133..9046)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_9"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.9e-10, bitscore:
                     28.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 2.4e-13, bitscore: 40.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKISRRNFMRGAAVGTMGAAAAGLLTACGNSASSTTGAPASSAA
                     SSAASSAVTKPSSPVDGKYVTKAMGHESWVHVATTFFDGKITACEVLSHEETIGIGNYA
                     CSRIPAAIVEHQSVNVPNLRGSSITSMAVKAAVKEAIELAGYNVDDFSKEVTIAASNEV
                     IEEEADVVIMGAGTSGLTCACRLLEAGYSVILVEKRDIPGGSMSMTYGGVATAGSKLQY
                     NYDVDGSFRSSAMGTLEGMMNFWQTMEKYHRTEFFNGEMPYMTKQYTVAGDLVDWMAGI
                     GIGFNTMGNYESATQYGASTPYLAPGCYEGGAGYAMMFMAQRVEKYEKGKIIYSTSVTD
                     LIKDESGRVVGFHAKGENGASYTLRGKAVCLASGGFAKNPEMLKKYSPDYADFFFNCAS
                     SMTGEGIQMGIDAGGYVECENRALPAFLSSYKSKFELAFIHQSAPGIMVNIKGDNIGNI
                     VSDNHYTMAKAKLNKDNGDTFYYVFDESSAVKLRDSESYGFNGYVAMFEKGEAVHYDSV
                     EKASEELNLPNLADAIEANNAAALAGEPDEFGRRNCPYIETRDGLWAIRVDPTFYLTTA
                     GLAIDTDCHVLTEDKKAIPGLYAAGDVCGSIEEKDAKQYGMGFDAALTYGYIMGETLKK
                     EI"
     CDS             9272..10189
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 143.2; E-value: 1.7e-43)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg80_10"
                     /transl_table=11
                     /translation="MTIYQLECFIAVAEELNFSAAAERLFTTQPAITYQINALEKETGL
                     HLFERTTRRTKLTAAGQSFYLDMVQMTSFGRQALKKAQDIQDADRSHLTVGLRQLFDYS
                     TFSSILAQFQHQFPNACVDVVPQDNRRPLEQLRSGQLDIGFFYATEHSRDRDISFTPLF
                     ALGYHVLMNPNSPLADRRALHLADLKGQSVVSSGAFDSFLSACQGPSLEQLAQVGVDCS
                     KITPSFEGALIMIQMGTAMSIVPCLSTAVIPGIVKVPLLDFPPVTVEIAAMRHAPRLEV
                     QSFIEIAKQKYAHHPDPLRMEALI"
     CDS             complement(10327..11343)
                     /locus_tag="ctg80_11"
                     /transl_table=11
                     /translation="MIFKPAQLGMAKLDPQELEADKKACRKIGPCGVGKKALYLNSFYI
                     DRRYYLPYGSITRVFKRVAMSSGGFSGKGVFASMAYLVVEYDGGKQKQCNFKDERDVDA
                     LLEVLAKEQPQLHLLSAAGEQALEKKAAEKAARKLPELSEDAQHSLTVLRRAKEYLDAK
                     PELSAELSAAQRRKRAQLQSKPVYRYVALAIFVLGVAAAAYGLYSVFSHTGSYGVYFAL
                     FGFAAIFLFSSYNMLPTAHNNNNAIMKRAEKAEAAMAEYVKHYPHGAFPVKSWYAHPIV
                     LKQMMDAVEEGRAVTVPEALDAVKARLKSLNADVEVEQEEYDEVVVIKALFLNHDYQ"
ORIGIN
        1 cgaaggattt tgtcgggtga aacagacggc aaaatgatcg ggtgtgttgc ggggcggtaa
       61 atcttcgcag gaaataaaac cgcacagaat cgtttcttta cagaaatctc tgtggatttg
      121 ttgggaatga taacataagt acgaatgcgt gtcaacactt caggataatg aatacatcag
      181 atgaacgaaa cacacaaagt acaagcgaaa gcaaggctgc gttttagaag aatgttttaa
      241 ttttcgcagt tcaggcggac ttggacggta aacacaccgt ccttcttctt tgtgtagaag
      301 tcgccatggt tctcttgaac gatacgattt atgttcttta gtccgtaacc gtgatactct
      361 ccgatgcgga tgctgcgaac ggtatcgctg tatggattct caagccggta aaagagactg
      421 cgatactgct tgcgcagctg tagatgaatg attcgctgtt ctgctggcaa gtcgcagcag
      481 gcttcaatgg cattgtcaaa tgtgtttccg atgatgatgc tcaaagacaa cgatgagatc
      541 gtcagaactt caggaatcgt cacatccagt ttgactttga tgttattcct ttccgcaatt
      601 cgtaagtaat aattcaaaag agcatcaaca acaggatttc cgacagcaga aatatttgtg
      661 gaacgctcga aaacattcgt ggcggcctgt gcgatcttgt gaagttcttc ggtatcaccg
      721 tgttctgcaa ctgcctgcat cgccagaatg tatttcttca catcatgctg tagagaacgg
      781 acttcttcct gacgttcttt gagctgctgg tagtattcca tttgaaggtt gtactgctgc
      841 tcattgaact tgactttgaa tttttctagc tcattttccc ggagagcttc cacatagaac
      901 acgatcagga tgtttataag gagaagtaca gccataaggc cgaccatata atcagggtaa
      961 taatcatccg cagcatgata ctgtgccaca taacagaccg cgatacttgc gatttgaatc
     1021 gcaatgatcg gcaacagcca taggatgcgc agagcatttc cctttcggct gaaaaaatgt
     1081 gaaatcagaa ctacgagtgg aatttgaatc aggtttgaaa aaacaatata gaccaaccgt
     1141 gctgccccag cctgcatcag aatgtcggta tccgggatac gcagaccaat caggagcatt
     1201 gcaagcactt ccaccaaagc agccagtgta aagaaggctc cgcttgcgaa aaccgcctgc
     1261 cacggtcgca cctcatagaa cagcaatgca aggagaaatc cgccaactaa aagataaatc
     1321 gtgcgctgcg ttacccaatc cgggaataaa ctcaaagcgc actgcccagc gatcaagagt
     1381 gcaacatatg acgcatagaa ccaccttgag acgggttcct ttttgggaaa cagccgaccg
     1441 ataaaaagca gcaacagggc aatgttggca aagctccctg caaactcaac gaaataataa
     1501 agcatcatct tcccaaataa gcgttgaaga tctgattgaa ctcctgacgc ttcctcctgc
     1561 taatcggcag ctgatgtccg ctggaaagaa aaacagcggt tcccgtagcg taaacaatgt
     1621 gttccatgtt gacgagataa cttttgtgtg gtgacacaaa gcaccgtttg ggaagttgct
     1681 ccaaggcttc aggaatgctc attcgcaatg taaggtcttg ctccttacag tgaatcagaa
     1741 ctttatgtcc gtggctttcc agaaagtaaa tgtccgatgt ttccaaggac atggtaatac
     1801 catcgtattc gatcgtaaaa tgtttggagt tcagttcctg aaggacggca tccattgccg
     1861 cagcgaacag tgtctgatcc aaaggtttga caaggtagcg gaatgcaacg ccatatccct
     1921 gcacagcgta ctcatgccgc ttcgtgacaa ataccaccaa aggatgcttc tccatttgga
     1981 tcaaagactg cgccaactga aaaccgttgg atggcatctc gatatcgagc agcagcaaat
     2041 cgaaggattt tttctgcatt tgcaattcgc tcagaagttc attcccatcc atgtaagtct
     2101 caatgtcaaa gcagccttgc acatcgtact gctggacgct ttgaacaatg ccatcaaggt
     2161 ctgacttctc atcatcgcag actgcaacgt ggtacttcag catttcgaca acctccacaa
     2221 aataatgtcc tgctactatt atagactgtg caaaggctcc ttacaagtag cctgacctac
     2281 cacttttgtc accagaacga ccagttttgc caaacctctt gattttgctg aaatttatga
     2341 tacagtgaag caaaaatcag aagataaggt ggcgcaactg caatgtggga acgcacgctg
     2401 tctcaaaaat tagtccgtct tttctgcgag caaaaagtga tagatgaagc aaaggcggat
     2461 gcgtatgtct atgggtacga gttgctcata tcatctgttg tgagcgttct gcttgttgtt
     2521 ttaatcgctg ttgtgtgtgg tgatgtgcgg tacgcacttt catttttgat cgggtttatc
     2581 ccacagcgaa tctacattgg cggataccat gcaacatcgc acaccagatg ctatttggca
     2641 ttctccggac tggcacttat ctgcattttg ctaagtaagg caatcgcagc aaatcacctt
     2701 ttccgtatcc tgacaacagt agctcttttg ggcatctcta tctttctctc acctatcgaa
     2761 gcaaagaata agcctttaag tgaaaagaag cggtcaagtt acaagatggt cgcatctgtt
     2821 ctttcgtcaa tagatttcct gcttgccatt tttaatgtgc ttccgtatac acgtcatgta
     2881 gtttgctact atctctccaa atgggtattg attgtattct caacaattcc tttggttcaa
     2941 caaaaattta atgccaactt ttgtagatag ggaggtgata acatgaaaaa aaacaaatgg
     3001 gtactgcttc ttatcgcttt tgttgcattt ttggtattga tttattttat tggtgcttgc
     3061 cttaatgcaa cggcagaggc attgacaatt atttctctct gcatcggcat actggtcatt
     3121 tatttagtcg taaaagcaat caaatcaaaa taaggagttg aggtgcattt atgaaattta
     3181 gcgtaccgga aatcttaatg attatattaa caacagcagt cgtgataatc gcttttcttg
     3241 cacttgcaaa ataccttatc cgctatgctg tcaaattcta tattaaaata aaaggagatg
     3301 acttaaaatg acgttgagaa aaaggttgat ttcgctttgc atggtaatgg tattggtatt
     3361 ttcactttcg gctgtttgtg cttcggccgc acaagaggca gtagcagaac agcccactgt
     3421 ttcgatgtcc tttgatcttg acaatcgcgt caagcacgaa aaaactgtga gattgccaga
     3481 tggttcgatt gcaaagatca ctgccgaacc catcaatacg ggtcgagcac tatctggagt
     3541 gtggaagatt acaggaacaa atgggttggc aacaatggaa tattggattg aattggaaaa
     3601 agctggcctt tacacaaaaa ttaagcggac atgggggctt gcgataactg gaattatgac
     3661 atcgtatgaa gatgccaaga ttaacgttgt taggcagatg gaatcgcctg ttcttcctgc
     3721 tgttgttgag ggatatgcaa aattcacata ttttgacaat ccggttgtta cgctttggac
     3781 gaaaagtgga ggcgtgagag cctcgatttc tggcaatcag atcactacag agctgtactg
     3841 attttttcaa gaatttgctt gttaacagct tcagaatcac ttaaagaagt tcgccggata
     3901 tattttaaga tgtccggcga actttttaat tgttgtaaga cggaaaggaa aaaattctaa
     3961 atgtcttgat ttctctatga aaaaatggta tatacattat acgaaacaat gctttgaaag
     4021 aacgctccac cgttcaatga tgtagaatga gaggtgtccg ccatgactgc cgtgatctac
     4081 gcccgctatt ccagtgacaa ccagcgcgaa gaatccattg aaggccagat ccgtgaatgc
     4141 acggcctatg ccgaaaagaa tgacatcacc attgtcaagc actacattga ccgtgccatc
     4201 tctgccaaga cggataaccg ccctcaattc cagcagatga tcaaggacag cgacaagaag
     4261 ctgtttgaca ttgttctggt ctggaaactt gaccgttttg cccggaaccg ctatgacagt
     4321 gcccggtaca agacccagct gaagaagaac ggtgtcaagc ttatgtcggc tacggaaatc
     4381 atttccgagg ggccggaagg catcattctg gaatctgttc tggagggcta tgcagaatac
     4441 tactctgccg accttgccga aaaggttgtc cgtggacaga cagagaacat cctgaaaggc
     4501 cgctgcaatg gtggccgtgg aacctttggc tatacgctgg attccgagcg gaaattccac
     4561 attgacccgc ttgcctcccc tttcgtgctg gaatcgttca gaaagtaccg ggatggtctt
     4621 acgatgaaag agattcggga ctggttgaac gagaacggca tcaagaaccc ggtcggcggt
     4681 gagtttacct ataacagtgt cgaacatatg ctcaagaatc ggcggtacat cggagaactg
     4741 aaattccggg atgtggtcgt gccggatgcc atcccgccca tcattccgct ggaactgttt
     4801 gaggacgtgc aggaaaaaat cgccaaaaac aagaaagccc ctgcccggag aaaggcagag
     4861 gacgattacc tgctgaccac caagctgtac tgtggttact gcggtgcgct gatgtttggt
     4921 gaaagcggaa cgagccggac gggagaagtc caccgctatt ataaatgtgc gactgccaaa
     4981 aagaagaagg gctgtaagaa gaaaaccgtc cgcaaacagt ggctggaaga tctggtggtc
     5041 aatcagacca tgcaacttgt ccgggatgat gccgccatgg aatccatcat cgccaaggtc
     5101 atggagctgc aagaccggga gaacactaat cttcccctct atgagaagca gctccgggat
     5161 gcggaatcgg gtatccagaa tatgctcaat gcgattcagg ctggaatcct taccagttcc
     5221 accaaggaac gattggagca gctcgaagaa accaagcgtg agcttgaagc ccacattgcg
     5281 gaagaaaagc tggcaaagcc aaaaatcaaa gaggaattta tccgtttctg gctgatgcgc
     5341 ttccgtaaac tggacatgag cctgaaagac cagaggcaag cgttggtgga tacgttcatc
     5401 aattcgattt atctgtacga tgataaggtt ttgataacct ttaactataa agaaggtaca
     5461 cagaccatca cgtttgagga agcggcccaa gccgcatcaa aggaaaatgg ttcggatttg
     5521 gattgcttta ctgcaccaag gactgctgca caggttatgt gcagcagtcc tttttattat
     5581 tttatcgaat ccatcttgca aaagcggcac agtgccttat aatagaggct gtgccccggt
     5641 gtgcgcgggc acggttagga tgtataggat aaaggaaaaa agagtatggc ttctcaaacg
     5701 aatacgctga cggaaggccc tctggccaag cagatctttc tggtcagtct gccgttggcg
     5761 ctttccaacc tgctgcaggt gctgttcaac atgtcggacg tggcggtggt ggggcgcttt
     5821 gccggttcca cggcgctggg cgctgtgggc tccaccagca cgctggtgac cctgttcacc
     5881 ggctttctca ttggtctgag caacggcatc aacgtgctgg tggcgcgttt ttacggcgca
     5941 cgccacccca aggacgtgga aaagaccgtc cactcggcgg ccatcatcag cgccgttgcc
     6001 ggtgtggcgt tgctgctcat cggtctgctg ggctcccccg ccatgctgcg gctgctgaac
     6061 accaaagagg atctgctgcc cggcgcgatt ttgtatctgc gggtgtattt tctgggtatg
     6121 ccggcgctgg cgctgtacaa cttcggcaac gcggtgttca gctccatcgg cgacaccaaa
     6181 aagccgctga tgtatctgtc cattgccggt gcgctgaaca ttctgctgaa cctgttcttt
     6241 gtcatcgtgt gcaatttgag cgtggtgggc gtggcgctgg ccagcgccat cagccagtgc
     6301 gtttccgcgt ttctgatcct gcgggcgctg acccgggtgc aggactgcta cgcgctggac
     6361 ccgcacaaat tacagctgga cccggtgcag gccaagagca tccttgcgct gggtgtgccc
     6421 gccgggctgc agaatgctat ttttgccatt gccaacctgt tcattcaggc gggcgtcaac
     6481 tcctttgact ctttgatggt caagggcaac agcgccgccg ccaacgcgga tgggctgatc
     6541 tacgactgca tggcggcctt ctacatggcc tgcgccagct ttatgagcca gaactacggc
     6601 gcgggacggc ctgaccgggt gaagaagagc tacttcatca gtctgggcta ctccttcggc
     6661 gtggggtttg tgctgggcgc ggcgctgttc ttctgcgggc cggccttcct tgcactgttc
     6721 accaccgaag cggcggtcat tgatgccggc atgaagcgtg tagccgtgat ggcctttgcc
     6781 tacggcatct cggcctttat ggactgcacc atcgccgcct cccgcgggct gggcaagaca
     6841 gtgattccca ccgtcatcgt agtgctgggc tcctgcgtat tccgggtgat ctgggtgtac
     6901 accatctttg cccacttcca caccatcccg gcgctgtacc tgctgtaccc gtgcagctgg
     6961 atcctgaccg cactggcgga gatcgcctat ttcgccagct gctacaagcg tgccatggcg
     7021 attttccgca agcctgcggc ggcgtaagag gaaatatgat ataaaaaggg ctgctgcacg
     7081 gtttgtgcag cagcccttta tttatgcttt tgtcaggtgg tcagagcgca gctcagatct
     7141 ccttcttcag ggtctcgccc atgatgtagc cgtaggtcag agcggcgtcg aagcccatgc
     7201 cgtactgctt ggcgtccttc tcctcgatgg agccgcagac gtcgccggca gcgtacaagc
     7261 cggggatggc cttcttgtcc tcggtcagga cgtggcaatc ggtgtcgatg gccagacctg
     7321 cggtggtcag gtagaaggtg gggtcaacgc ggatggccca cagaccgtcg cgggtctcga
     7381 tgtaggggca gttgcggcgg ccgaactcat cgggctcgcc agccagagca gcggcgttgt
     7441 tggcctcgat ggcgtctgcc agattgggca ggttcagctc ctcagaggcc ttctccacgc
     7501 tgtcgtagtg cacagcctcg cccttctcga acatggcaac gtaaccgttg aagccgtagg
     7561 actcgctgtc gcgcagcttg acggcagagg actcgtcgaa cacatagtag aaggtgtcgc
     7621 cgttgtcctt gttcagcttt gccttggcca tggtgtagtg gttatcggag acgatgttgc
     7681 cgatgttgtc gcccttgatg ttgaccatga tgccgggggc agactggtgg atgaaggcca
     7741 gctcaaactt gctcttgtag ctggacagga aggcgggcag agcgcggttc tcgcactcca
     7801 catagccgcc ggcgtcgata cccatctgga tgccctcgcc ggtcatgctg gaggcgcaat
     7861 tgaagaagaa gtcggcgtag tcggggctgt acttcttcag catttcgggg ttcttggcaa
     7921 agccgccgga ggcaaggcag accgccttgc cgcgcagggt atagcttgcg ccgttctcgc
     7981 ccttggcgtg gaagcccaca acacggccgc tttcgtcctt gatcaggtcg gtgacgctgg
     8041 tggagtagat gatcttgccc ttctcgtact tctccacgcg ctgtgccatg aacatcatgg
     8101 cgtagcctgc gccgccctcg tagcagccgg gtgccagata cggggtggaa gcgccgtact
     8161 gggtagcgct ttcgtagttg cccatggtgt tgaagccgat gccgatgcct gccatccagt
     8221 ccaccagatc accggcgacg gtgtactgct tggtcatgta gggcatttca ccgttgaaga
     8281 actcggtgcg gtggtacttc tccatggtct gccagaagtt catcatgccc tccagcgtgc
     8341 ccatggcaga gctgcggaag ctgccgtcca catcgtagtt gtactgcagc ttggagcctg
     8401 cggtggcaac gccgccgtag gtcatggaca tggagccgcc ggggatatcg cgcttctcca
     8461 ccagaatgac gctgtagccg gcctccagca ggcggcaggc gcaggtcagg ccggaggtgc
     8521 cggcacccat gatgacgaca tcagcctctt cctcgatgac ctcgttggaa gcagcgatgg
     8581 tgacctcctt ggagaagtcg tccacgttat aaccggccag ctcgatggcc tccttcacag
     8641 ctgccttgac agccatggag gtgatggagg agccgcgcag gttgggcacg ttgacgctct
     8701 ggtgctcgac gatagcggca gggatgcggg agcaggcata gttgccgatg ccgatggtct
     8761 cctcgtgaga cagcacctca caggcagtga tcttgccgtc aaagaaggtg gtggcaacgt
     8821 gcacccagct ttcgtgaccc atagccttgg tgacgtactt gccatctacc ggggaggagg
     8881 gcttggtcac agcggaggag gcagcagagg aagctgcgga ggaagcggga gcaccggtgg
     8941 tgctggaagc ggagttgccg caggcggtca gcagaccggc agcagctgcg cccatggtgc
     9001 ccacagcggc accgcgcata aagttgcgac gagagatctt agccataagg ttcgcctttc
     9061 tttttctttt ctcttctttt ttgcgttttt cctgttcctt cgtgcatttt gaacattgat
     9121 acgattatag caaagttttg ccccggtgtg aaatacaaat ttgtgtcaga atttatcaaa
     9181 tctctttata aatcgttttc cctttacggc ctgtgcggaa tcctgtataa taaagatgac
     9241 cagcttttta cacaaggagg tgcgccattc tatgacgatt taccagttag agtgctttat
     9301 tgccgtagca gaggagctga atttcagcgc cgccgccgag cggctgttca ccacccagcc
     9361 cgccatcacc taccagatca atgcgctgga aaaggagacc gggctgcacc tgttcgagcg
     9421 caccacccgc cgcaccaagc tgaccgctgc cgggcagtcc ttttatctgg acatggtgca
     9481 gatgaccagc tttgggcggc aggcgctgaa gaaggcgcag gatattcagg acgccgaccg
     9541 ctcccacctg accgtcgggc tgcggcagct gttcgattac agcacctttt ccagcattct
     9601 ggcccagttc cagcaccagt ttcccaacgc ctgcgtagac gttgtgccgc aggacaaccg
     9661 ccgcccactg gaacagctgc gctccgggca gctggatatc ggctttttct acgccaccga
     9721 gcactcccgc gaccgggaca tctcctttac gcccctgttc gccctgggct accatgtgct
     9781 gatgaacccc aactctcccc ttgccgaccg gcgggcgctg catctggcag acctgaaggg
     9841 gcagagcgtg gtgtcctccg gcgcattcga cagctttctg tccgcctgtc aggggccgtc
     9901 gctggagcag ctggcgcagg tgggggtgga ttgcagcaag atcaccccca gctttgaggg
     9961 tgcgctgatc atgatccaga tgggcaccgc catgtctatc gtgccctgcc tttccacggc
    10021 ggtgatcccg ggcatcgtca aggtgccgct gctggatttt cccccggtga cggtggagat
    10081 cgccgccatg cgccacgcac cccggctgga ggtacagtcc tttatcgaga tcgccaagca
    10141 gaaatacgcc catcaccccg acccgctgcg gatggaggcg ctgatctgag gcacagctgc
    10201 tactgttcaa aagtcccctt gtgtcatagg gcttcgccgc ctgttctgaa cagcagctcc
    10261 tgccctgtaa aagcagaaaa ccggacagcc tgcgggctgt ccggtttttt gtgctatcga
    10321 aaggttttac tgataatcgt ggttgaggaa cagggccttg atgaccacca cctcgtcata
    10381 ttcttcctgc tccacctcca cgtccgcgtt caaggatttc aggcgtgcct tgactgcatc
    10441 cagtgcctcg ggcacggtga cggcgcggcc ctcctccacg gcgtccatca tctgcttgag
    10501 cacgatgggg tgggcgtacc agcttttcac cgggaacgcc ccgtgggggt agtgcttgac
    10561 atactctgcc atggctgcct cggccttttc agcacgcttc atgatggcgt tgttgttatt
    10621 gtgggcggtg ggcagcatat tgtagctgga aaacaggaag atggcggcaa agccgaacag
    10681 cgcaaagtac acgccgtagc tgccggtgtg gctgaacacg gaatacagac cgtaggccgc
    10741 agccgcaacg cccagcacaa agatggccag cgccacatag cggtacaccg gtttgctttg
    10801 cagctgcgca cgcttgcggc gctgggcagc gctcagctcg gcggaaagct ccggctttgc
    10861 gtccagatac tcctttgccc gacgcagcac ggtaaggctg tgctgcgcgt cctcggaaag
    10921 ctccggcagc ttgcgggcgg ccttttcggc agcctttttc tccagcgcct gctcaccggc
    10981 ggcgctcagc agatgcagct gcggctgctc cttggcaagc acttccagca gggcgtccac
    11041 gtcccgctcg tccttgaagt tgcactgctt ctgcttgccg ccgtcgtact ccaccacaag
    11101 ataggccatg gaggcaaaca cgcccttgcc ggaaaagccg ccggagctca tagccacccg
    11161 cttgaacacc cgggtgatgc tgccgtaggg cagataatag cggcggtcga tgtaaaagct
    11221 gttcaggtac agcgcctttt tgcctacgcc gcaggggccg atcttccggc aggctttttt
    11281 gtctgcctcc agctcctgcg ggtcaagctt tgccatgccc agctgtgcgg gtttgaaaat
    11341 catgggtagt tcccttcttt gctttaaatt ctacgcccct attttcccac gggacggggg
    11401 caattgcaag ccctgatttt ttcaaaaaac agcgcccgcc gctgtacggt caggcagcgg
    11461 cgggcgcaag ttacttacgg aaatatggag ccgtcagttc cttatgcctt ggaagtagag
    11521 ctcttcttgg tagcatggag gaacagagcc agcattgcga tggcaaagac gatgccgatg
    11581 gggtaagcaa cggcggtgtt gtaagccacc agcttgccgt ctgcgtaagt attgatcatc
    11641 ttgcccaggc actcaggtgc cagcacgaag taggtgcagg acacagcgct catgaaggtt
    11701 gcaggcacgg cggtgatcca gaagttcttc ttctccttga acaggtacat ggaagcagcc
    11761 cacaggacga tcatagccag cgtctggttg gtccagctga agtaacgcca gatgacggtg
    11821 tagttgatga agcccagtgc gttgccgatg ccaaggaaag caccaacgcc cagcacgggg
    11881 acacacagct tcaggcggtt tgcgtagctg tcctgatcga tcttgagcca gtcggccaga
    11941 gtcagacgag cggaacggaa tgcagtatca ccagaggtga tggggcagat aacgacaccg
    12001 atcatagcca gtgccacgcc gacattaccc atggtcttga gacagacgtc gtagatagca
    12061 gcagactgac cggcagccag agcctcggcc agaccgacca tcttgccatc ggtgatggtg
    12121 tacagtgcgc agccggcagc agcccagatc agagcgatga tgccctcgct gaccattgca
    12181 ccgtagaata cgaagtgacc ctgcttctca ctcttcatgc agcgagccat caaaggcgac
    12241 tgggtggagt ggaaaccgga aatagcacca caggcaacgg tgatgaacat gaagctccag
    12301 ataggagtgt tggaggggtg catattgctg aagtttgccc agatctcggg gatggtgtag
    12361 gcggggttgg tgaagatacc aaaaataacg cccacagcca tgatgatcag gcagatgccg
    12421 aacacagggt agatcttacc gatgatggca tcaatggaga taaaggttgc gatgaagtag
    12481 tacaccagaa tgatgatcag ccagaacagg gtggtggtca gcacgccgga cataccgccg
    12541 ttcttgcaca gggtaacgat caggcctgcg gggccgactg cgaacacggt accgaccatg
    12601 atcagcagca ccacagagaa cacacgcatg atgttctgca tcacggggcc cagatagcgg
    12661 ccggtgacct cggcgatgga agcgccctca ttgcgctcgc tcatcatacc ggagaagtag
    12721 tcatgtacgc cgccggcaaa gatggtgccg aaggtgatcc acaggaacac cacgggaccc
    12781 cacagagcac cctgcagtgc accaaagatg gggcccagac ctgcaatgtt cagcagctgg
    12841 acgaggaaca gcttccactg gggcatcaca acgtagtcga cgccatcgtt gatgcgcaca
    12901 gcaggagttt cgcggtcgtc cggtccgaac gtgttgtcca cgatcttacc atagacaaag
    12961 tagccgatga
//
