LOCUS       c00136_gnlPro..        14005 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDNPHBBN_136.
ACCESSION   c00136_gnlPro..
VERSION     c00136_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:43:23
            Original ID  :: gnl|Prokka|MDNPHBBN_136
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14005
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14005
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:4005]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..4005
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14005
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14005
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(3..974)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_1"
                     /sec_met_domain="HGD-D (E-value: 9.1e-22, bitscore: 69.4,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYHYPKFTPEMKKTHTILIPNMAVTQFRLMEYALRCEGYKCELL
                     GNCGSAVAQLGLKYVHNDTCYPALLVIGQFLDALNSGKYDLEHTALLITQTGGGCRASN
                     YIHLLRKALVKAGYPQIPVASLNFSGLEKDSGFQMTLPLARKCIACIFYGDMLCALRNQ
                     VAPYENEKGAADRMMDRWIARLGRALLAGKGFTSREMKHTFPLIAKEFATIPVTRVPKV
                     KVGVVGEIYVKYSPLGNNDLQKFLESQDCEVNFPGLMGFVQYCAFNMGEDHVLYGGKLA
                     VKVGTDQFLNWLDSVERVMLKAETDAGFYAPGPFKELVEKPKG"
     CDS             complement(1066..4005)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_2"
                     /sec_met_domain="HGD-D (E-value: 3.1e-15, bitscore: 47.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1e-38, bitscore:
                     124.6, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRVGLDIGSTTIKCVVLGEHDELLYSTYERHYSHILEKAQELLRR
                     IDAEHLHGRKALLSISGSAGMGLADSCGVPFVQEVFSTRVAVKRFMPKTDCVIELGGED
                     AKILFLTNGTEVRMNGSCAGGTGAFIDQMATLLKMSAEEMNKAAEQAQRTYTIASRCGV
                     FAKSDVQPLINQGARTEDIAASIYKAVVNQTIAGLAQGRPIKGNILYLGGPLTFSTVLR
                     KSFDEALNVTGTCPENSLLYVALGAALYADKEFVLTEVADALDKYAATATYASEPPLFA
                     SKEEYEAFHARHMSHSVPRVAFSAHCGPVHIGIDSGSTTVKLVVVDEKSQILYTNYQPN
                     LGNPLPLIREQLLKIYKEHPGLQVASVTTTGYGEELVKNAFRCDYGLVETVAHFTAAKY
                     FMPDVDFIIDIGGQDMKCFKIEDGAISNIFLNEACSSGCGSFLQTFAQALGYDVKEFAA
                     LGLFADRPVDLGSRCTVFMNSSVKQAQKDGASIENISAGLSISVVKNALYKVIRASSPE
                     ELGRKIVVQGGTFYNEAVLRAFEKEMGVEVIRPDIAGLMGAYGAALYGLRQSHKNNQTT
                     SAMMDEQELEKFAQQVVSVKCGGCGNHCQLTVNTFADGRKFISGNRCDKPVTGKSEDNS
                     LNLYAYKQQLLASYKPVPGKRGSIGIPMCLGFYELLPFWYAFWTSLGFAVHTSPVSTRG
                     LYLAGQATIPSDTACFPAKLSHGHIKALSQMQLDAIFYPCLTYNVDEGLGDNHYNCPVV
                     AYYPEVLAGNCPELEGKKFIYDYVGIHRPKDFVHKMAKEVLPKYFGGISEREVQAAADA
                     AYAEYEAHMAKIRVKGSEIIDEARRQGKRIIVLAGRPYHVDPEVNHGIDHLITRHGAAV
                     VTEDSISNRVQKFPTSVLNQWTYHSRLYAAAKYCTTQKDMDLVQLVSFGCGVDAITTDE
                     TREILQRGNKLYTQLKIDEITNLGAVNIRLRSLFAALDERDEAAAEKSE"
     CDS             complement(4451..5227)
                     /locus_tag="ctg136_3"
                     /transl_table=11
                     /translation="MSTKPIDSTAATRFDLSAAALHILAMALMLMDHLWATLLPAQEWL
                     TCAGRLAFPIFAFMAVEGYFHTHDLKKYTLRLLLFALLSEIPFDLMYGGTWFYPVHQNV
                     IWTLLLGILGIHLMETVRKKQKTGLYLLVSALVVVAGAVLGTLGMVDYYGAGVLTVFIF
                     YFFHGHGRKWWCLLGQLVALYWVNVELLGGLMYPIQLFGMDFELCQQGLALLALVPIWL
                     YRGRQGYHSKPFQYACYAFYPVHMLLLVLVLNFVNQ"
     CDS             complement(5339..5494)
                     /locus_tag="ctg136_4"
                     /transl_table=11
                     /translation="MKRCKLFYLIGLLFFLAAALNFVTGGDHATAVVWRCLGATFLLLG
                     CSQQKK"
     CDS             complement(5912..6550)
                     /locus_tag="ctg136_5"
                     /transl_table=11
                     /translation="MNLKEAFRYQNKLQSLLDEAQGILDCDANVTKVANTYLRHKVMPE
                     AEDETVMDVAQTEYAEQITDVARFMLYLLEEKSRLFAAIRKAKDALDMDMDSEVSLNAA
                     RQSIARTFKRMNDLRSSEQLLSGGGTGYRFNAEGNQISYCCDVKRVTTINYDRKVIHAA
                     LGKLNRQADETSNRLDLCLVTSKVDYTVPFDVNASFAEAFETYLENVQN"
     CDS             complement(6711..6965)
                     /locus_tag="ctg136_6"
                     /transl_table=11
                     /translation="MLRIEYFDKERFMRQLSASHGSVLLHLDNGKTCDLKKDTTARSML
                     QMMDTAPQKGFDLTVTDPADVTGFLRYMLEAGRTERVAG"
     CDS             7235..8167
                     /locus_tag="ctg136_7"
                     /transl_table=11
                     /translation="MAYQTSCASYTSGRVGLSSATAVVADAAGREQAQHGSPLFPIACY
                     AEDLSCFSVAWHWHEEFEFILAALGPIHVDVNKTRLTLQTGQGVFINSGALHAVEPAEG
                     RALLHSGVFQPRLVGGMDTVFWQKLIRPLLQPGTPPFFLLDEAVPWQRQVLLCLREAWK
                     GVADEPFDYENRVRYHLTAALRLLITQCVSGKVKVSEQEQIASERMKQMLRYVEEHYAE
                     ELTVEKLADCVALSESACLRSFRQFLGITPIQYVKQFRVEKAAELLRSTRLKTGEVGLE
                     CGFSDASYFIKTFREIKHCTPREYRIRFC"
     CDS             complement(8215..9012)
                     /gene_functions="resistance (resist) AAC3 (Score: 107.9;
                     E-value: 2.8e-33)"
                     /gene_kind="resistance"
                     /locus_tag="ctg136_8"
                     /transl_table=11
                     /translation="MAYTKADLKHDLAAMGLTGNETILIHSSMKSIGPVEGGADTVLDA
                     WMEFFAEGLLLLPTHTWRFINEENRVFDVRRSPCCVGILPELFRHRPGVVRSLHPTHSM
                     AAYGKGAAAYLEGELDANTPCTPGGCYDRLRAAHGKVLLLGVTHARNTFIHSVEEVLNV
                     PNCLTDKPMQMTVVDEAGAQHTVYMRRHYNAQQPHISEDFVKLEQAYLDCGAARNTKFG
                     DARCILCDAEGLFRVTRHVLAPNPEAFVTEPVIPPERWQGGIL"
     CDS             9487..10188
                     /locus_tag="ctg136_9"
                     /transl_table=11
                     /translation="MATLQHTDELYHILEDEICALKILPGEALSENQLCKRFGVSRTPI
                     RSVLQRLEQNRFVQIIPCKGTIVTAIDTGVVDQLIFQRVAVEGMVFRDFVQSCSPMEIL
                     AVEHLYNMLLEVAAGRSDPENFDFNHFLSCDLAMHEYWFHKTSKEYLWEQMTRPQADYS
                     RFIRLDIVGARNVSSVVSEHAEMLRILREKDLDAIEPLMRTHLYGGVSRMGSKIYSDEY
                     RGYFKLPENKK"
     CDS             10713..11171
                     /locus_tag="ctg136_10"
                     /transl_table=11
                     /translation="MKKFLKTLVVGLCLFTLLCCALPAAFAADKTSGSKKEENVYAIGM
                     DAQGGICSTVVTYTNLSGKLESTPEQPTMTGYTFDGWYTEPVGGSKVTTSTVFTSDATI
                     YAHWTAKAGTSTVPQPTTQPAATQWQKYVGPALVAGALLTTLLVATMF"
     CDS             11218..11451
                     /locus_tag="ctg136_11"
                     /transl_table=11
                     /translation="MTTSTMKMPASYSTIEAEEMTYLDGGASNAYQSFLDIGKVFNYIA
                     RIFSGASSIINNVNVIYQSFVSLNSLLGSFGK"
     CDS             11855..12394
                     /locus_tag="ctg136_12"
                     /transl_table=11
                     /translation="MADRELRRMHRAELIEIIYALKQSEDQLKAQNAALTAQLQDRQLR
                     LESAGSIAQAALELNNVFAAAQAAADDYLHSVQASLADTNATAANTLSQARSEAKRILE
                     QAQADADSLKAQAQQECDAMTAAAAQKRTQTEADCKAMVEQAEQEVQQRWQAFDRKAND
                     LLDQYHSTDGLPSEET"
     CDS             12391..12981
                     /locus_tag="ctg136_13"
                     /transl_table=11
                     /translation="MKKRDIRFASIPSTEEVAAERERLAYQSRYQRVLRSTIYILVVVA
                     AAAVLLATLFLPVLQVSGDSMNPTLNDKDIILLVKSNHIENGELCGFYWQNKLLLKRII
                     GQPGDVIDMDVNGVVSVNGVALDEPYVDALTVGECDIRFPYQVPENRYFVLGDHRATSI
                     DSRSSVIGCVEKSQIVGRVFLRIWPLSSFSLIH"
ORIGIN
        1 acccccttgg gcttttccac cagctccttg aaggggcccg gtgcatagaa cccggcgtcc
       61 gtctctgcct tgagcatgac acgctccacg ctgtccaacc agttgaggaa ctggtcggtg
      121 cctaccttta cagccagctt gccgccgtac agcacatgat cctcgcccat gttgaaggcg
      181 cagtactgca caaagcccat cagaccgggg aagttcacct cgcagtcctg actttccagg
      241 aatttttgca ggtcattgtt gcccagcggg ctgtatttga cgtagatctc gcccacaacg
      301 cccaccttga ccttgggcac ccgggtgacc gggatagtgg caaattcctt tgcgatgagc
      361 gggaaggtgt gcttcatttc ccgggaagta aagccttttc cggccagcaa ggcacggccc
      421 agacgggcga tccagcggtc catcatgcgg tcagcagcac ccttttcgtt ctcgtagggg
      481 gccacctgat tgcgcagcgc acacagcata tcgccgtaga agatgcaggc gatacacttg
      541 cgcgccagcg ggagggtcat ctggaagccg ctgtcctttt ccaggccgga aaagttcagg
      601 cttgccaccg ggatctgcgg atatccagcc ttgaccagcg ccttgcgcag cagatggatg
      661 tagttggagg cacggcagcc gccgccggtc tgggtgatca gcagcgcggt atgttccaga
      721 tcatacttgc cgctgttcag cgcatccaga aactggccga tgaccagcag cgccgggtag
      781 caggtatcgt tgtggacata cttcagcccc agctgtgcca cggcactgcc gcagttgccc
      841 agcagctcac acttgtagcc ctcgcagcgc agtgcgtact ccataagccg gaactgggta
      901 acggccatgt tggggatgag gatggtgtgg gtctttttca tctccggggt aaatttggga
      961 taatgatatt ccataggttc ctcctatgtt gctctaaaca agatagtccc cgcaaaagct
     1021 tcccctcgcc ggggggaagc ccttcagcct atctcagggt ttcttttatt ctgacttttc
     1081 tgcggcggcc tcgtcccgct cgtccagtgc ggcaaacagg ctgcgcagac ggatgttcac
     1141 ggcaccgagg ttcgtgatct cgtcgatctt caactgggtg tacagcttgt tgccccgctg
     1201 caaaatctcg cgggtctcgt cggtggtaat ggcatccacg ccacagccga aggacaccag
     1261 ctgcaccaga tccatatcct tttgggtggt gcagtacttg gcggcagcat acaggcggct
     1321 gtggtaggtc cactggttca gcacactggt ggggaacttc tgcacccggt tggagatgct
     1381 gtcctcggta accaccgcag ccccgtggcg ggtgatcagg tggtcgatgc cgtggttgac
     1441 ctccgggtct acatggtagg ggcggcctgc cagcacaata atgcgcttac cctgacggcg
     1501 cgcctcgtca atgatctcac tgccctttac ccggatcttt gccatgtgcg cttcgtactc
     1561 cgcgtaggca gcatcggctg cggcctgcac ctcccgctcg gagatgccgc caaagtactt
     1621 gggcagcacc tcctttgcca tcttgtgcac aaaatccttg ggacggtgga tgcccacata
     1681 atcatagatg aactttttgc cttccagctc cgggcagttg cctgccagaa cctccgggta
     1741 gtaggccacc accgggcagt tataatggtt gtcgcccaag ccctcgtcca cattgtaggt
     1801 caggcagggg tagaagatgg cgtccagctg catctggctc agcgccttga tgtggccgtg
     1861 gctcagcttt gccgggaagc aggcggtatc gctggggatg gtagcctgtc cggccagata
     1921 cagcccgcgg gtggacaccg ggctggtgtg caccgcaaag ccaaggctcg tccagaaggc
     1981 gtaccagaag ggcagcagct cgtagaagcc cagacacatc gggataccga tagaaccgcg
     2041 cttgccgggc acaggcttgt agctggccag cagctgctgc ttgtaggcgt acaggttcag
     2101 gctgttgtcc tcgcttttgc cggtaacggg cttatcgcag cggttgccag agatgaactt
     2161 gcggccatcg gcaaaggtgt tgacggtcag ctggcaatgg ttgccgcagc cgccgcactt
     2221 gacgctgacc acctgttgtg caaatttttc cagttcctgc tcgtccatca tggcagaggt
     2281 ggtctggttg tttttatggc tctggcgcag gccgtacaag gcagcgccgt aagcgcccat
     2341 cagaccggca atgtccggcc ggatgacctc cacgcccatc tctttttcaa aggcacggag
     2401 cacggcttca ttataaaagg taccgccctg taccacgatc ttgcggccca gctcttccgg
     2461 gctggaagcg cggatcacct tgtacagcgc gttcttgacc acgctgatgg acaggcctgc
     2521 ggagatattc tcgatgctgg caccgtcctt ttgcgcctgc ttgaccgagc tgttcatgaa
     2581 cacagtgcag cggctgccca agtccaccgg gcggtctgcg aacagaccca gcgcggcaaa
     2641 ctccttgacg tcatagccca gtgcctgcgc aaaggtctgc aaaaagctgc cgcagccgga
     2701 ggagcaggcc tcgttcagga agatgttgct gatggcgccg tcctcgatct tgaagcactt
     2761 catgtcctgc ccgccgatgt caatgatgaa gtccacgtcc ggcataaagt acttggcagc
     2821 ggtaaaatgc gccaccgttt ccaccagacc gtaatcacag cggaaagcgt tctttaccaa
     2881 ctcctcgccg tagccggtgg tggtaacact ggccacctgc agccccgggt gctccttgta
     2941 gatcttgagc agctgctccc gaatcagagg cagcgggttg ccaaggttgg gctgatagtt
     3001 ggtgtacaaa atctggctct tttcgtccac caccaccagc ttgacggtgg tagaaccgga
     3061 gtcgatgccg atatgcaccg gcccgcagtg ggcactaaaa gccacgcggg gcacactgtg
     3121 ggacatgtgc cgtgcgtgga aagcctcgta ctcctccttg ctggcgaaca gcggcggctc
     3181 gctggcatag gtagcagtgg cggcgtactt gtccagcgca tcggccacct cggtgagcac
     3241 aaattcctta tcggcataca acgcagcgcc cagcgccaca tacagcagac tgttttccgg
     3301 gcaggtaccg gtcacgttca gcgcttcgtc aaagctcttg cgcagcacgg tgctgaaagt
     3361 gagcgggccg cccagataaa ggatattgcc cttgatgggg cggccctgtg ccagaccggc
     3421 tatggtctgg ttgaccacag ccttatagat gctggcggcg atatcctcgg tgcgggcacc
     3481 ctgattgatc agcggctgca cgtcactttt tgcaaacacg ccgcagcggg aagcgatggt
     3541 ataggtgcgc tgcgcctgct cggcagcctt gttcatttcc tcggcgctca tcttcagcag
     3601 ggtagccatc tggtcgatga aagcaccggt gccgccggca cagctgccgt tcatgcgcac
     3661 ctcggtgccg ttggtcaaaa acaggatctt ggcatcctcg ccgcccagct caatgacaca
     3721 atcagtcttt ggcataaagc gcttgaccgc cacgcgggtg gagaacacct cctgcacaaa
     3781 gggcacaccg cagctgtcgg ctaagcccat accggcagag ccggagatgc tgagcagcgc
     3841 cttgcggcca tgcagatgct cggcatcaat gcgccgcagc agctcctgcg ccttttccag
     3901 aatatgacta taatgtcgtt cgtatgtaga atacagcagt tcatcatgct cgcccagcac
     3961 cacgcacttg atggtggtgc taccgatgtc aagacctact ctcaccttgt ttttcctcct
     4021 aaggacaaat aaccggaaca taacgccccg gctgctatgg caaacaagtc gtttgcggca
     4081 aagacccgca acggcgtttt ttctttttag cttcccgcat tgcgcagcta cgtcattttc
     4141 aaacagtacg cgttataaaa aacacagcaa atgcactttt gcatacatta ttataatcca
     4201 atcgcgggcg gcattcaatc catgttgtct attttacacg aaaaaaatag tattttttgc
     4261 tcaaaaggct gaactttttg tgaacatgtg tcggttttcc cgcaaaaaaa gccgccgcac
     4321 agcgctttgt gcagcggcct tataccggcg gaacgatttc gaatggctcc gcatacgctt
     4381 tggctatttt cagcggaagt tcctctctac gccccacgcg taaaaatgtt tttggagtgc
     4441 tccattctcc ttactgattc acgaaattca gcaccagaac cagcagcagc atgtgcacgg
     4501 ggtaaaaggc gtagcaggca tactggaaag gcttgctgtg gtagccctgc cgaccgcggt
     4561 acagccagat gggcaccagt gccagcagcg ccagcccctg ctggcaaagc tcaaagtcca
     4621 tgccgaagag ctgaatgggg tacataagcc cgcccagcag ctccacgttg acccagtaca
     4681 gcgctaccag ctgccccagc agacaccacc acttgcgccc gtgcccgtga aaaaagtaga
     4741 agatgaacac agtcagcacc cctgcaccgt agtagtccac catgcccagc gtgcccagca
     4801 ccgcgcccgc caccaccaca agggcggata ccagcaggta cagtcctgtt ttttgctttt
     4861 tgcgcaccgt ttccatcaag tggataccca gaatgcccaa aagcagcgtc cagatgacgt
     4921 tctggtgcac cgggtagaac catgtgccgc cgtacatcaa atcgaagggg atttccgaaa
     4981 gcagggcaaa caacagcaga cgcagggtgt attttttcaa atcgtgggtg tggaagtagc
     5041 cctccaccgc cataaacgca aagatgggaa aggccaagcg cccggcacag gtcagccatt
     5101 cctgcgcggg cagcaacgtc gcccacaggt ggtccatcag catcagcgcc atagcaagga
     5161 tatgaagcgc cgctgcgctc aggtcaaagc gggtcgcggc agtggaatcg atcggtttgg
     5221 ttgacataca catacctcgt ctttgtcgaa atttggtcgt tctgtctgga atacgaacga
     5281 gccccgcaaa gaattgcagc cccgggagtt cttttcccgc cggggccggc ttgctgcttt
     5341 attttttctg ctgcgaacac cctagcaaca aaaaggtagc gccaaggcag cgccatacca
     5401 ctgccgtagc gtgatcccct ccggtaacaa agttcagcgc cgcagcaaga aaaaacagca
     5461 gcccgatgag ataaaacagc ttacaccttt tcatagctca tacctccggt cttggttttt
     5521 tcaccggcta ttttggatac ggcaagcgca ggggcggctg tcattttact ccgcgtgcaa
     5581 aggggcgcag agcgcccacc cggcacgcag aaagtgtgtg cccgcagcag tctgcggggc
     5641 aaattcatga agggtggctt gcctgcctgc ccatggagac gtaagcgcaa aagcaggaat
     5701 gcgggaagga gcaagggacg gtttcggcga aaaagcgtct ggcggtggcg gaaaagccga
     5761 acgcaagatt ttttcataat agctggctcg taaggtgagc cgtaccaaaa cttccttgcg
     5821 gaaatgtgca gcgttatagt tcatctgcac ctgaaccggc agctgtgcac ccggcgcttg
     5881 ccgcacccaa aatagccggt ggaacgttta tctagttttg gacattttcc agataggtct
     5941 caaatgcctc ggcaaagctg gcgttcacat caaaggggac agtgtagtct accttggagg
     6001 tcacaaggca gagatccagc cggttggagg tttcgtctgc ctgccggttc agcttgccca
     6061 gcgcggcatg gatgaccttg cggtcgtagt tgatggtggt cacccgcttc acatcgcagc
     6121 agtaggagat ctggttgccc tcggcgttga agcggtagcc ggtgcctccg ccggagagca
     6181 gctgctcaga actgcgcagg tcgttcatcc gtttgaaggt gcgggcaatg ctctgccgcg
     6241 cggcattcag gctgacctcg ctgtccatat ccatgtccag cgcatccttt gccttgcgga
     6301 tggcggcaaa caggcggctc ttctcctcca gcagatagag catgaaccgg gcaacgtcgg
     6361 tgatctgctc tgcatattcg gtctgtgcca cgtccataac ggtctcgtcc tcggcctcgg
     6421 gcatcacctt atggcgcaga taggtgttgg ccaccttggt cacgttggca tcgcagtcca
     6481 gaatgccctg cgcctcgtcc agcagagact ggagcttgtt ctggtagcgg aatgcttcct
     6541 tcaggttcat agtcgttccc tccatcttgt tttttctgct ttcagcttac cacagactgc
     6601 ccgcccgcgc aagctttccg gtaaaatgag caaaacgccc gccccggcat gaccgggacg
     6661 ggcgctttgc atttgctgtg acacttattg ggataagaga ttggcattac tcagccggcc
     6721 acgcgctcgg tgcggcctgc ctccagcata tagcgcagga agccggtcac gtcggcaggg
     6781 tcggtcacgg tgaggtcaaa gcccttttgg ggggcagtgt ccatcatctg cagcatggag
     6841 cgtgcggtag tgtccttttt caggtcgcag gtcttgccgt tgtccagatg cagcagcacg
     6901 ctgccgtggc tggcagaaag ctggcgcatg aaacgttcct tatcaaaata ctcgatacga
     6961 agcataggaa tacctccttg atgaaatggt ttatgttaca cttgccgtcc agtcctcttt
     7021 ggacagacgg cgggagaatg gcagttttgc ccggcagtgg aaacgcttgc acagcttgcg
     7081 tcccagctgc cttggtgcta tgctgagctt ggaagctctg ataggataat accacaaaac
     7141 aatcgcaaat tatagaacag aaccgcatag tatatgcaac aaaaccggca ttgacaaaaa
     7201 acattcaaag tattgcggaa aggatttggt gaatatggca tatcagacaa gctgtgcctc
     7261 ttataccagc gggcgggtgg ggctgtccag cgctactgcc gtggtggccg atgccgccgg
     7321 gcgggagcag gcccagcacg gcagcccgct gttccctatc gcctgctatg ccgaggatct
     7381 ttcctgcttt tcggtggcgt ggcactggca cgaggagttc gagtttattc tggcggcgct
     7441 gggacctatc catgtagatg tgaacaagac ccggctgacc ctgcagaccg ggcagggggt
     7501 gtttatcaac tccggggcgc tgcacgcggt agagcctgcc gagggcaggg cgctgctgca
     7561 ctccggcgtg ttccagccca gacttgtcgg cggcatggac accgtattct ggcaaaaact
     7621 catccggccg cttttgcagc cgggcacgcc gcccttcttt ttgctggacg aggccgtacc
     7681 atggcagcgg caggtgctgc tctgcctgcg ggaggcgtgg aagggcgtgg cggacgagcc
     7741 tttcgactac gagaaccggg tgcgttacca ccttactgcc gccctgcggc tgctcattac
     7801 ccaatgcgtc agcggcaaag taaaggtatc ggagcaggag cagattgcct cggagcggat
     7861 gaagcagatg ctgcgctatg tagaggagca ctacgctgag gagctgaccg tggaaaaact
     7921 ggccgactgc gttgccctga gcgaaagtgc ctgtctgcgc agtttccggc agtttttggg
     7981 tatcacgccc atccagtacg tcaagcagtt ccgggtggaa aaagccgccg agctgctgcg
     8041 ctccacccgg ctcaagaccg gcgaggtggg gctggaatgc ggtttttcgg acgccagcta
     8101 ctttatcaag accttccggg agatcaagca ctgcacccct cgggagtacc gtatccgctt
     8161 ctgctgagca aaaagtaaaa aatgccgggc agctgcaagc tgcccggcat tgcattataa
     8221 aattcccccc tgccagcgct ccggcgggat gaccggctcg gtgacaaagg cctcggggtt
     8281 cggggcaaga acatggcggg tgacccggaa aagcccctcg gcgtcgcaca aaatgcatct
     8341 tgcatcgcca aatttcgtgt tccgagctgc gccgcagtcc agatacgcct gttccagctt
     8401 gacgaaatcc tccgagatgt gcggctgctg tgcgttgtag tggcggcgca tatagacggt
     8461 gtgctgcgcc ccggcttcgt ccaccacggt catctgcatg ggcttgtcgg tcaggcagtt
     8521 cggcacgttc agtacctcct ccacgctatg gataaaggtg ttgcgggcgt gggtgacccc
     8581 cagcagcagc actttgccgt gggctgcccg cagccggtcg tagcagccgc cgggagtgca
     8641 gggggtgttg gcgtccagct ctccttccag atacgcagcc gcccccttgc cgtaagccgc
     8701 catgctgtgg gtggggtgca gcgagcgcac caccccgggg cgatgccgga acagctccgg
     8761 cagaatgccc acacagcacg ggctgcggcg cacatcgaac acccggtttt cctcgttgat
     8821 gaaccgccat gtgtgggtgg gcagcagcag caagccctcc gcaaaaaact ccatccatgc
     8881 gtccagaacc gtgtctgcgc cgccctccac tgggccgatg gacttcatgg aggaatggat
     8941 caggatggtc tcgttgcctg tcagccccat tgctgcaagg tcgtgcttga ggtcagcctt
     9001 tgtatatgcc atgtcgtttc tcctttttgg gcattttgtc tgtacccagt ttaccgcctt
     9061 ttgtgcggca aagcaagcac gcacgcaaaa aaggcaaaca ccctgttgta tttgccggag
     9121 acgagccggt atctgcgggg tgtgtgccct tgcagctttt ttagtaaaat cctgtataca
     9181 gcatatcatc tcgcagcgtt accgcgaaac aagcacagcg ccttgcaatt atagcaattt
     9241 gacagttgtt tcctgttttc tttgtgcatt tggtacaaca gtcacttgat tgcagcattt
     9301 tatcagcact tttcccgcat tgcaaagtgg tatatcagtt tttcagtttc aggaacagtt
     9361 ccgtgcgcga gtgcgcattc ttgtatacaa gtattcaaat taagttccat tccagcattg
     9421 acattcagtt gctgtaacgg tacaatgata ctaagattac atttaccgga taaatggaga
     9481 acaactatgg ctacattaca gcacactgat gagctctatc atattctcga ggacgagatc
     9541 tgcgcgttga agatcctgcc cggggaagcg ctgagcgaaa accagctgtg caagcggttc
     9601 ggcgtttccc gcactcctat ccgcagcgtt ttgcagcggc tggagcagaa ccgctttgtg
     9661 cagatcattc cctgcaaggg caccattgtt accgccatcg acaccggcgt ggtggaccag
     9721 ctcatcttcc agcgtgttgc agtggagggc atggtgttcc gggactttgt gcagagctgc
     9781 tcgcccatgg agatccttgc ggtagaacac ctttataata tgctgctgga agtcgctgca
     9841 gggcgcagcg acccggagaa ctttgatttc aaccacttcc tcagctgcga ccttgccatg
     9901 cacgagtact ggttccacaa gaccagcaag gagtaccttt gggagcagat gacccgcccg
     9961 caggcagact actcccgctt tatccgtctg gacatcgtgg gtgcacgcaa cgtgtccagc
    10021 gtcgtcagcg agcacgccga gatgctgcgc atcctgcgtg agaaggatct ggacgccatc
    10081 gagccgctga tgcgcaccca cctgtacggc ggtgtgagcc gtatgggcag caagatctac
    10141 tcggacgaat accgcggcta cttcaagctg ccggagaaca aaaaataaag aaggccgctg
    10201 cacagttccc tgtgcagcgg ccttcttctg gttgcgccag caggagtcga acctacgatg
    10261 ggggagtcaa agtcccctgc cttaccgctt ggcgatggcg catcatgcaa aacagtatag
    10321 catattttcc gctgttccac aagaggtgcg ccgcattttt gcagcttttt ctgtgcgctg
    10381 tctgccgcac ttgcggcggt ttgggtcggt ttttgggctt tgcggccggg accctgcgtt
    10441 ttccatatcc ttccatgttt ttacgaaagg caagttttgc gggatgcgtt tttcaaaaaa
    10501 cacagtccgc agggggcaca agattcatat tgcaaaggtg aaatttattt ttttcctgat
    10561 ttttcttatt attttctcaa aagactgtat tttttgttgc gattctggta cactggatgt
    10621 gataaaaata agttgaagaa actacgccga tgtccgggct gtccccgggc ggggcagtgt
    10681 ctccatcttt gtgaaggaaa gcgagggatc tcatgaaaaa attcctgaaa acgctggtgg
    10741 tcgggctttg cctgttcacg ctgctgtgct gcgcactgcc ggctgcattt gccgccgaca
    10801 aaacttcagg gagcaaaaag gaagagaacg tgtacgccat tggtatggat gcccaaggcg
    10861 gcatctgctc caccgtggta acctacacga acctgtccgg caaactggag agcacgcccg
    10921 agcagcctac catgacgggc tacacctttg atggctggta caccgagccg gtgggcggca
    10981 gcaaggtgac cacctccacc gtgttcacct ccgacgccac catctacgcc cactggactg
    11041 ccaaggccgg tacttctacc gtgccgcagc ccaccaccca gcctgccgcc acccagtggc
    11101 aaaagtatgt aggccctgcc cttgtggccg gtgccctgct tactaccctg ctggtcgcca
    11161 ccatgttctg aacactgctg taaacacaat gacaccattg aagaaaggga tcttaccatg
    11221 actacttcta ccatgaaaat gcccgccagc tattccacca tcgaagccga ggagatgacc
    11281 tatctggacg gcggcgccag caacgcttat cagtccttcc tggacatcgg caaggtgttc
    11341 aactacattg cccgcatctt ctccggtgca agctccatca tcaacaatgt taacgtcatc
    11401 taccagtcct ttgtatcgct gaacagcctg ctgggcagct tcggcaagta aaagcatcac
    11461 cccaaagttc agatccggga gccgcgcttt tttcgaaaag tgcggctccc gtttttcgta
    11521 cacactgtaa ttcagtacat tactgcgcag cacttcacgt tccagaattg tgaacaactt
    11581 tttaagtttt tggggggtca gtggccgttt tttggacatt tttaatatat aaagcaaaaa
    11641 aatgcgatat tttttcagct ttatctcttg attttgtatc tgatttgtta tattactgtt
    11701 acagtgggtg tgctagaata aggttgttta taaaatgccc ttcagaccgc gtaaaaaatc
    11761 gtggcggcaa gcgttttttc aggtattttt gttaagtaat ttcgtaatct tcgaaaacct
    11821 tttcgttctt tatgatttgg gagtatgtac acaaatggca gatcgtgaac tgcggcggat
    11881 gcaccgcgct gaactgatag agatcatcta tgcgctgaag cagagcgagg accagctcaa
    11941 ggcgcagaac gccgcgctta ccgcgcagct gcaggaccgg cagctacggc tggaaagcgc
    12001 cggttccatc gcgcaggccg cgctggagct gaacaacgtg ttcgccgccg cgcaggccgc
    12061 cgccgatgac tatctgcact cggtgcaggc cagtcttgcg gacaccaacg ccaccgccgc
    12121 caataccctt tcgcaggcgc gcagcgaggc caagcgcatt ctggagcagg cacaggcaga
    12181 cgccgacagc ctgaaagcgc aggcgcagca ggaatgcgac gccatgactg ccgccgccgc
    12241 gcaaaaacgc acccagaccg aggccgactg caaagccatg gtggagcagg ccgagcagga
    12301 ggtgcagcag cgctggcagg catttgaccg caaggccaac gatctgctgg accaatacca
    12361 cagcaccgac ggtctgcctt cggaggaaac atgaaaaaac gcgatatccg gttcgcttcc
    12421 atcccttcca ccgaggaagt ggccgcagaa cgtgagcgtc ttgcgtacca gagccgctac
    12481 cagcgggtgc tgcgcagtac gatctatatt ctggtggtgg tggccgcagc agccgtgctg
    12541 ctggctacgc tgtttctgcc ggtgcttcag gtctccggcg acagcatgaa ccctacgttg
    12601 aatgataaag acattatcct gctggtaaaa tccaaccaca ttgaaaacgg cgagttgtgc
    12661 gggttttact ggcagaacaa gctgctgctc aagcgcatca tcgggcagcc cggtgatgtg
    12721 atcgatatgg acgtgaacgg cgtagtctcg gtaaacggcg tggcgctgga cgaaccctat
    12781 gtggacgcgc tgaccgtggg cgaatgcgac atccggttcc cctatcaggt gccggaaaac
    12841 cgctacttcg tgctgggcga ccaccgtgcc acctccatcg acagccgcag cagcgtgata
    12901 ggctgcgttg aaaaaagcca gatcgtgggc agggttttcc tgaggatatg gcccttgtcc
    12961 agcttctcgt tgatccattg accccgggag gaggtatttc gttatgaacg acattcttaa
    13021 aacgtacatg gagcggttcc gtgagaaccg gcacaccctg cggcgctaca ccgcatttgt
    13081 gctggcactt gccataatca ccaccctgtt cgtcaactgg cagctgcatg gcgtgggcat
    13141 ctcgatgacc gcgcagtacc agtgcggcga ggaggagcac acccacaccg cggattgcta
    13201 caccaaggtg ctcacctgcg gttacgagga aggcgagctt gaaaatgcgg acgagctggc
    13261 cgccgctgct gccaccagcc agcccaccgt tgaggctgag cccgcgccgc tggcactgga
    13321 gccgcagatc gagtttgtgc cccacgagca caccgacgac tgctacaccg aggtgcagac
    13381 cctgacctgc atggaagaag agcacgtcca cggtgacgac tgcttcgacc ccgaggacgg
    13441 cagcctgatc tgcgagaaat ttgagcatac ccacgatgaa aactgctata ccaccgagta
    13501 cgagctgacc tgtggactgg aagagggcga gcttgtggag caggtggtgg agcccaccca
    13561 gagcgccgag ttggcggcta tggctgtggc cgagcctgtg gcactggagc cgacggtgga
    13621 caccgtggag cccatctacc accaccacac cgacgcctgc tacgaggaag tgctcacctg
    13681 ccccctgccg gagcaccacc ataccgttgc ctgcctgagc gacacttctg ccgaccttga
    13741 gacccccgag gagtggcagg ccgccaacgc cgaggccgtg atgaccggca actgggccga
    13801 ggatctggtc agcgtggcaa agacccagct gggctacgag cagagcgaga aaaactttga
    13861 aatcgacccc gcggacggcg tgaccctgcg ctactactcc cgctacggtc agtcctacgg
    13921 caacccctac ggcgagtggg acgtgatgtt cctctcttac tgcctgaagt acgccggtat
    13981 cccccagagc gctatcccgc aggag
//
