LOCUS       c00102_gnlPro..        11432 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GOCEDJGG_102.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:19:53
            Original ID  :: gnl|Prokka|GOCEDJGG_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11432
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11432
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1808:7039]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1809..7039
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..11432
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11432
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             415..1623
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_1"
                     /sec_met_domain="Peptidase_S11 (E-value: 2.2e-51, bitscore:
                     164.1, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRRFLSLLLSMSLLIFSPVRVRAQDVPAESELYAKSAVLMDADS
                     GRILYEKNGHEAMANASTTKILTCIVALENCDPASVVTVSKNAASQPKVHLGMHEGQQF
                     YLRDLLYGLMLESYNDCAVAIAEFAAGEVQGFAALMNAKAEKLGCEDSYFITPNGLDAK
                     DDAGFHHTTAADLAKIMKYCIKESLKSDEFLEITRTAQYSFSDAEGKCTYQCTNHNAFL
                     QMMEGALSGKTGFTGTAGYCYVGALQREDKTLIVALLACGWPNNKTYKWSDTRKLMNYG
                     LEQFKKIDLLQIEPDEAELAPIEVRDGQGGQIGETVYLKPVVRNYAGEESILAPLSSEV
                     TLKYEIADQLYAPVKSGDYIGKIRYMLGEETLAERCVVAGETIGKIDYPWCLGQVLRLL
                     WIE"
     CDS             1809..3245
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_2"
                     /sec_met_domain="CT_Vparvula (E-value: 2.7e-125, bitscore:
                     408.3, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSSNDSLAMQRITRLVDENSFIEIGSLVTARSTDFNLAATDTPS
                     DGVITGHGLIDGNLVFIYSQDASVLNGTIGEMHAKKIAAVYDMAMKMGAPVIGFIDCAG
                     VRLQESVDALDGFGLIYAKEVAASGVVPQISAVFGSCGGGLAVVPALSDFAFIEESKGK
                     MFVNSPNAIDGNRIEKCDTSSAAFQADENGCIDATGTEDEILADIRELVGMLPLNNEGD
                     VYTDECADDLNRACESMDAMKGDPRYLLSEISDSHTFFETKAGYARDMVTGFIKLNGMT
                     VGAVANCTTVYDEEGKESEKFDNVLSAKGCEKAAEFVSFCDAFEIPVLTLTNVKGYKAC
                     KCSEKRLAKALAHLTSAFAGATCPKVNLITGEAYGTAYVAMNSKSIGADFVYAWPDAKV
                     GMMDADLAVKIMYADASADELAEKAKEYDALQGSVMTAARRGYVDLIVDPADTRKYLVD
                     AFELLYTKCAYTPDKKHGTK"
     CDS             3232..3984
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_3"
                     /sec_met_domain="OAD_gamma (E-value: 2.8e-25, bitscore:
                     78.4, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQNRKVKFMKKKLSLILCLCFMALGLAACGTDPTTVDYFGMTYD
                     ELQSSMEQEVSALVGLTDDNRTYIQSYGSDTAMKLVESWDEATSDVGAYQGLGEFNITK
                     AQKTLTVDQYVEYQNREVIVSYIYTYNYETEQPELTDASADKVYTLGEKMEKAALNTLM
                     GMGTVFVVLILISLIIYCFRFISVIQNKAAGKGKKNEAEAGAVVEQIGQREEQLTDDLE
                     LVAIISAAVAASTGASADSFVVRSIRRR"
     CDS             4026..4391
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 56.9; E-value:
                     4.7e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 8.4e-19, bitscore:
                     56.9, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGNVYDVTVEENGAVSAPAAAPRRAAAPAAAPAAKPA
                     AAAGAGSVKIEAGAAGKVFKLEKSVGDAVKKGDSIMVREIMKMETPVVATQDGTVASIN
                     VSVGDMVEAGALLATLN"
     CDS             4407..5555
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_5"
                     /sec_met_domain="OAD_beta (E-value: 2.4e-157, bitscore:
                     512.8, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYFSETMGNLLHQTAFFNLTWGNFVMIIVACFFLYLAIAKGFEP
                     LLLVPIAFGMLLVNIYPDIFADPEQMSNGVGGLFHYFYVLDEWSILPSLIFLGVGAMTD
                     FGPLIANPISFLLGAAAQFGIFGAYFLAIMMGFNDKAAAAVSIIGGADGPTSIFLAGKL
                     GQSGLMGPIAVAAYSYMALVPIIQPPIMKLFTTKKERAIKMENLRPVSKLEKILFPIVV
                     TVVVCTILPTTAPLVGMLMLGNLFRESGVVRQLTDTASNALMYIVVILLGTSVGASTSA
                     EAFLNTTTLKIVALGLIAFMFGTAAGVLFGKLLCFLTKGKINPLIGSAGVSAVPMAARV
                     SQKVGAEEDPTNFLLMHAMGPNVAGVIGTAVAAGVFMAIFGI"
     CDS             5621..7039
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_6"
                     /sec_met_domain="HMGL-like (E-value: 8.5e-46, bitscore:
                     146.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 1.1e-59, bitscore:
                     191.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVVKKPLKITETVLRDAHQSLIATRMTTEQMLPIVDKMDKVGY
                     NAVECWGGATFDACLRFLKEDPWDRLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSIANGIDIIRIFDCLNDVRNLQTAVTACNKEKGHAQVALSYTLGDAYTLDYWME
                     MAKKVEDMGADSLCIKDMAGLLVPTKATELIQALKSATNLPIELHTHYTSGVASMTYMK
                     AVEAGCDIIDTAMSPFSMGTSQPATEVMVEAFKGTEFDTGLDQNLLAEIADYFRPMREE
                     ALESGLMNPKVLGVNIKTLLYQVPGGMLSNLLSQLKEQGKEDKFEEVLAEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKVATKETKDVLLGKYGQTVKPFNPEIVDKVLGE
                     EKKNAITCRPADLLEPELDKIEAEMKQWKQQDEDVLSYALFPQVATEFFKYREAQQKKV
                     DASVADTKNGAYPV"
     CDS             complement(7102..7584)
                     /locus_tag="ctg102_7"
                     /transl_table=11
                     /translation="MRDITPATNFIHTLMQSPPDASAWIAGGNNFPSISGLARFYATDY
                     EGTLVEVEVFGLPNVATPGSSNFYGMHIHENGVCVSPFTSAGAHYSRTPAEHPNHSGDM
                     PPLLGNQGYAWMTFYDKRFTIPEIIGKSLIIHRMPDNFTTQPAGDSGERIACGVIK"
     CDS             7746..8678
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SIS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_8"
                     /sec_met_domain="SIS (E-value: 1.3e-24, bitscore: 76.1,
                     seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNTNDLSNRINDAYSKLSKGQKRLATYITDNYDKAVFLTAAKLG
                     EVVGVSESTVVRFATHLGYKGYPEFQSALEELVRNKLNSIQRMEVTYGRISQSKILETV
                     LKSDADKIHSTLEKIDQNAFELAVDTILHAKHIYIIGIRSCAPLASFMAFYFTLMFPNV
                     HLIQTSSSSEIFEQMVRIGKEDVIIGISFPRYSMRTLKAMEFANNRSAKVITLTDSVHS
                     PMNLYSSCNLIADSDMASIVDSLVAPLSVINALIVALCMKKQNEVAKTLEMLEDIWDEY
                     QVYENDEINYIDDSIKMRYGKVGDAELYE"
     CDS             8671..9900
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 58.4; E-value:
                     2.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_9"
                     /sec_met_domain="HI0933_like (E-value: 4.4e-137, bitscore:
                     446.5, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVIVVGGGPAGMFAAIAAAERGHEVVLLEKNEKLGKKLYITGK
                     GRCNITNAGDMDTLFANVMTNPKFLYSAFYDYDNQRVIDFFEENGLATKVERGNRVFPV
                     SDHSSDVIATLQRVLKRTGVMVQLHAEVRQILTGEGAVRGVKLADGSVLEAERVILATG
                     GFSYQTTGSTGDGYRFARELGHTVTQITPSLVPFYVKETCAARMQGLALKNVQVRIRDG
                     KKLLYDEFGEMLFTHFGVSGPLILSASAAIKPGRVEKELAMEIDLKPALTEEQLDARLL
                     REFEEAKNKQFKNAVVHLFPAKMIPVMLEAGAIDPEKKVNEITREERMGFVHLIKAFPL
                     TLCGVRDFNEAIITRGGVSVKEVNPSTMESKLVPGLYFCGELLDLDAMTGGFNLQIAWS
                     TGHLAGESIE"
     CDS             9919..10581
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg102_10"
                     /sec_met_domain="Cytidylate_kin (E-value: 4.7e-81,
                     bitscore: 261.1, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMNIAIDGPAGAGKSTIAKKLAKKLAFVYVDTGAMYRAMAYYFL
                     QNGIAPDDEQAIAAACPKVDVTIVYENGEQQVLLNGENVNGVIRTEEVGNMASATSVYP
                     VVRTKLVELQRQLATKTDVIMDGRDIGTCVLPDAQVKIYLTASVATRAKRRYDELTAKG
                     TQCNLEEIEKDIEDRDYRDMHRETSPLKQAKDAVLVDSSEMNIDEVVDAIYQIYARV"
     CDS             10587..11432
                     /locus_tag="ctg102_11"
                     /transl_table=11
                     /translation="MNVILAKSAGFCFGVKRAVDTVYERILEKEPLYTFGPIIHNEEVV
                     RDLEEKGVVVVNDVDELAGKPQGTVIIRAHGVERGVCEKIQTLGFSIVDATCPFVLKIH
                     RLVERYSGEDCHIVIVGNASHPEVKGIKSWSNAEDTRVIGTREEAEKYDASHGKKVCIV
                     SQTTFNYNKFQELVEIIKEKGYDIIVLNTICNATEERQTEARAIAEQVDAMIVIGGRNS
                     SNTQKLFEICKNECKNTYYIQTVKDLDLAEVRSVDNVGITAGASTPNNIIEEVQKNVRN
                     E"
ORIGIN
        1 caaaacataa ccgcgcgaag ccgatgtctg agtcggcatc tgccttattt tcaatagcag
       61 atgccggcga gtttcggttc gcgcggtttt atattgtctg cgaagaggtg cccttaggga
      121 caccagaaag tccgcccatt gtctccggtg tgccggacat gtacccgtcg gattgtccaa
      181 acgtggaaga gacacggaat ccgatgcaaa cattcagccg gaagaaatgc tcacattttt
      241 ctccaacgaa tattccatct gcatttccac atgaaatccc caagtgtgtt tctaataata
      301 ttacttatca aagcacaata tgcttattgc ggcagttcct ttttacatac cgtttctgtt
      361 ctgcaaaaaa tgagggacgc atatacatca gtgaagtcat tttgggagaa tggcatgtat
      421 cgacgctttc tttctctatt gttaagtatg agtttactta ttttttcgcc tgtgcgtgtc
      481 cgggcgcagg atgtgccggc agagtcggaa ctgtacgcaa aatctgccgt tttgatggat
      541 gcggattccg gaagaattct ctatgagaaa aacgggcatg aagcgatggc gaatgcgagc
      601 acgacaaaga ttttaacctg tatcgtggca ctggaaaact gtgatccggc gagcgtggtt
      661 acggtgtcaa aaaatgcggc gtcccagccg aaggtacatc tggggatgca cgagggacaa
      721 cagttttatc tgagggatct tttatatggc ctgatgctgg aatcctacaa tgactgtgcg
      781 gtggccatcg cggaatttgc ggcgggggag gtgcagggat ttgccgcgct gatgaatgcg
      841 aaggcagaga aactcggctg tgaggacagc tactttatta caccgaacgg actggatgcg
      901 aaggatgatg ccgggtttca tcacacgacg gcggcagacc ttgctaagat tatgaaatat
      961 tgtattaagg aatcgttaaa aagcgacgaa tttctcgaga ttacacggac ggcgcagtat
     1021 tctttttctg atgcagaggg gaaatgcacg taccagtgca cgaaccacaa tgcatttttg
     1081 cagatgatgg aaggggcgct ttccgggaaa acgggattta ccggaaccgc cggatactgc
     1141 tatgtcggag cgctgcagcg ggaggacaaa acgttgatcg tggcgctgct cgcctgtgga
     1201 tggccgaaca acaagaccta taagtggtcc gacaccagaa aactcatgaa ttacggattg
     1261 gagcagttca aaaagatcga cctgttgcag attgagccgg acgaagcgga gcttgcgccc
     1321 atagaggtgc gggacggaca gggcggacaa atcggcgaaa cggtgtattt aaaaccggtt
     1381 gtcaggaact atgcagggga ggagagtatc ctggcgccgc taagcagtga ggttacgctt
     1441 aagtatgaga ttgcagacca gctgtatgca ccggtgaaga gcggcgatta catcgggaag
     1501 attcgttata tgctggggga ggagacgctc gcggagcgat gtgtggtagc cggggagaca
     1561 atcggaaaga tcgattatcc atggtgtctg gggcaggtgc ttcggcttct ctggatcgaa
     1621 taaaaaacac aaacaaaaag cgtcaaaaaa ttaacaattt acttgaaata ttgcagaaaa
     1681 gcaattataa tttaacatag cgtaatttgt tgaattttta tacaaagacg catggattta
     1741 catcattcac tatgaagccg catcccaaat ggatgtggac aacaatttat agatggaggg
     1801 caaaaagaat gaatagtagc aatgatagcc tggctatgca gcgcatcacc aggttagtcg
     1861 acgagaacag tttcattgag atcggttctc tcgtaaccgc aagaagcaca gattttaatc
     1921 ttgcagcaac ggatactcct tccgacggag tcatcacagg acacggcctg attgacggca
     1981 atctggtgtt catttacagc caggacgctt ctgttttaaa cggaacaatc ggcgagatgc
     2041 atgcgaagaa gatcgctgca gtgtatgaca tggcgatgaa gatgggagca ccggtgatcg
     2101 gctttatcga ttgcgcggga gtccgtttac aggagtctgt agatgcgctt gacggcttcg
     2161 gactgatcta tgcaaaagaa gttgcagcat ccggcgtggt tccgcagatt tcagccgtat
     2221 tcggcagctg cggcggtgga ctggcagtgg taccggcact ttctgatttt gcttttatcg
     2281 aagaatccaa aggaaagatg tttgtgaatt ctccgaacgc aattgacgga aaccgcatcg
     2341 agaagtgcga cacatcatct gcggcattcc aggcagatga gaacggctgc atcgacgcga
     2401 cgggaacaga ggatgagatc cttgcagaca tccgtgagct ggtcggcatg cttccgctca
     2461 acaacgaggg agatgtctac acagacgagt gtgcggatga cctgaaccgt gcatgcgaga
     2521 gcatggatgc catgaagggt gatccgagat atcttctcag tgagatttcg gacagccata
     2581 cattcttcga gacaaaggca ggctatgcca gagatatggt gaccggattt atcaagttaa
     2641 acggtatgac ggtcggcgca gttgcaaact gcacaacggt atacgacgaa gagggcaaag
     2701 agagcgagaa gtttgacaat gttctttctg caaagggatg tgagaaggca gcagagttcg
     2761 tatctttctg cgacgcattc gagattccgg tactgactct gacaaatgtc aagggctaca
     2821 aggcatgcaa gtgctctgaa aagcgtcttg caaaggcact tgctcatctg acctccgcat
     2881 ttgcgggagc tacatgtccg aaggtgaacc tgatcacggg agaggcatac ggtaccgctt
     2941 atgttgctat gaattccaag tctatcggtg cggatttcgt atatgcatgg ccggacgcaa
     3001 aggtcggcat gatggatgcg gatcttgcag taaagatcat gtacgcggat gcatctgcgg
     3061 atgagcttgc agagaaggca aaggaatatg atgcactgca gggcagcgtt atgacagcag
     3121 ccagaagagg ctatgtggat ctgatcgttg atccggcaga tacgagaaag tatctggtag
     3181 atgcgtttga actgttatac acaaagtgtg catatacacc ggacaagaaa catggaacaa
     3241 aatagaaagg tgaagtttat gaagaaaaaa ttatctctta tactttgtct ttgctttatg
     3301 gctctgggac ttgcagcatg cggaacagat ccgacaacgg ttgactattt cggaatgact
     3361 tacgatgaac tgcagagcag catggaacag gaagtttccg cgctggttgg tcttacggac
     3421 gacaacagaa cctatatcca gtcctacggc agcgatacgg caatgaaact tgtcgagagc
     3481 tgggatgagg cgacaagtga tgtcggcgca tatcagggac ttggagaatt caatatcaca
     3541 aaggcacaga aaaccttaac agtagatcag tatgtagagt atcagaatcg tgaagtcatc
     3601 gtttcttaca tctatacata caattacgag accgagcagc cggagcttac tgatgcatcc
     3661 gcggacaagg tatatacgct gggtgagaag atggagaagg ctgcgttaaa taccctgatg
     3721 ggaatgggaa ccgtattcgt ggttctgatc ctgatcagcc ttattattta ctgtttccgc
     3781 tttatctctg taatacagaa caaggcggcc ggcaagggca agaagaacga ggcagaggca
     3841 ggcgctgtgg tagagcagat cggacagcgt gaagagcagc ttaccgatga tcttgaactt
     3901 gtggcaatta tttccgcagc ggttgcggca agcaccggtg catccgcgga ttctttcgtt
     3961 gtgagatcga tccgcagacg ctaattcgta taaatgaaaa gaaatcatat taggaggata
     4021 tttcaatgaa aagctataca attacagtaa atggcaatgt atatgatgta accgtagaag
     4081 agaacggcgc agtgagcgca ccggcagcag caccgagacg tgcagcagca ccggcggcag
     4141 cacctgcagc aaagccggct gcagcagcag gcgcaggcag cgttaagatt gaggcaggcg
     4201 cagcaggaaa ggtattcaaa cttgagaagt ctgtcggtga tgccgttaag aagggagaca
     4261 gcatcatggt tcgtgagatc atgaagatgg agactccggt cgttgcaacg caggacggta
     4321 cggtagcaag tatcaacgta agtgttggag atatggtaga agcgggcgca ttacttgcaa
     4381 cattaaacta atttaggagg aagacaatga gctattttag tgagacaatg gggaacctcc
     4441 tgcatcagac cgctttcttt aaccttacct ggggaaattt tgtgatgatc attgtcgcat
     4501 gctttttcct gtatctggct atcgcgaagg ggtttgagcc attgcttctt gttccgattg
     4561 cattcggtat gctgcttgta aatatctatc cggatatttt tgcagacccg gagcagatga
     4621 gcaatggtgt aggtggttta ttccactact tttatgtgtt agacgagtgg tcaatcttac
     4681 cgtctctgat tttccttgga gtcggtgcta tgacagattt cggaccgctg attgcaaacc
     4741 cgatcagttt cctgcttgga gctgcagctc agttcggtat tttcggagcg tacttccttg
     4801 caatcatgat gggctttaat gataaggcag cagctgctgt ttccatcatc ggtggagccg
     4861 acggaccgac ctccattttc cttgccggaa agttaggaca gtcgggactg atgggaccga
     4921 tcgctgtggc ggcatattcc tatatggcgc ttgtgccgat catccagccg ccaattatga
     4981 agctgtttac aaccaaaaaa gagcgtgcca tcaagatgga gaacttaaga ccggtttcca
     5041 agctggagaa gattctcttc ccgatcgtgg ttacggtggt tgtatgtacg attcttccga
     5101 cgacagcgcc gctggttggt atgctgatgc tcggtaacct gttccgcgag agcggtgtgg
     5161 tccgccagct gaccgatacc gcatccaacg cattgatgta catcgtagtt atcctgctcg
     5221 gtacttccgt aggtgcatct acgagtgcgg aggcgttctt aaatacaacg acattaaaga
     5281 tcgttgcact tggactgatt gcatttatgt tcggtacagc agccggtgtc ctgtttggta
     5341 agctgttatg cttcctcaca aagggcaaga tcaatcctct gatcggatct gccggtgtat
     5401 ctgccgttcc tatggcagcc cgtgtatccc agaaagtcgg cgcggaggaa gatccgacga
     5461 acttcctgct gatgcatgcg atgggaccga acgttgccgg cgttatcggt actgcagtag
     5521 cagccggtgt attcatggca attttcggaa tttagtgaaa gagcaaatgc cgtcatagac
     5581 ggatagcggt atcaaagtat ccgctgataa ggaggaaaaa atgtcagaag ttgttaaaaa
     5641 acctttaaaa ataacagaga cggtgctgcg tgatgcgcac cagtccctga ttgcgacaag
     5701 aatgacaacc gagcagatgc ttccgatcgt agacaagatg gataaggtcg gatacaatgc
     5761 ggttgagtgc tggggcggtg ctaccttcga tgcatgcctt cgtttcctga aggaagatcc
     5821 gtgggatcgt ctccgcaagt taagagacgg atttaagaac accaagcttc agatgctgtt
     5881 tcgtggacag aacatcttag gatatcgtcc gtatgcggat gatgtggtag agtatttcgt
     5941 acagaaatcg atcgcaaacg gtattgatat cattcgtatt ttcgactgct taaacgatgt
     6001 ccgcaacctg cagacagccg ttaccgcatg taacaaagaa aaaggacatg cacaggtcgc
     6061 attatcctat acacttggcg atgcctacac tctggattac tggatggaga tggcgaagaa
     6121 ggtagaggat atgggtgctg attccttatg tatcaaggat atggcaggtc ttttggttcc
     6181 gacgaaggca accgagctga ttcaggcatt aaagtctgca accaaccttc cgatcgagct
     6241 ccatacacac tatacttccg gtgtcgcttc catgacatac atgaaggcgg ttgaggcagg
     6301 ctgtgacatt atcgatacag caatgtctcc gttctccatg ggaaccagcc agccggcaac
     6361 cgaggttatg gtagaggcat tcaagggcac agagttcgat accggtctgg atcagaacct
     6421 gttagctgag atcgctgact acttccgtcc gatgcgtgag gaagcgttag agagcggtct
     6481 gatgaacccg aaggttctcg gcgttaacat caagactctg ttatatcagg taccgggtgg
     6541 tatgttatcc aaccttctgt ctcagttaaa agagcagggt aaggaagaca agttcgagga
     6601 ggttcttgca gaggttccgc gtgtgcgtaa agacctcggt gagccgccac ttgttacacc
     6661 gtcctcacag atcgttggta cacaggctgt gttcaacgta ctgatgggag agcgctacaa
     6721 agtggcaacc aaggagacca aagacgtact gcttggaaag tacggtcaga ctgtaaaacc
     6781 gttcaacccg gagatcgtag acaaggtact tggcgaggag aagaagaacg ccattacctg
     6841 ccgtccggca gatctgcttg agccggagct ggataagatc gaggctgaga tgaagcagtg
     6901 gaagcagcag gatgaggatg tactctccta cgcactgttc ccgcaggttg caaccgaatt
     6961 cttcaagtac cgtgaggcgc agcagaagaa agtcgatgca agcgtcgcag ataccaagaa
     7021 cggagcatat ccggtataat caaaaaacag ttaaaacaaa aagcgggtga gtagtcacct
     7081 gcttttttgc tgcctttttt gctattttat cacaccgcag gcaatccgtt cgccggagtc
     7141 gcccgcgggc tgcgttgtaa agttatccgg catccggtga atgatgaggg attttccgat
     7201 gatttccgga attgtaaaac gcttgtcata aaatgtcatc caggcataac cctggttgcc
     7261 cagaagcgga ggcatgtcgc cgctgtgatt cgggtgttcg gccggcgtac ggctgtaatg
     7321 ggcaccggca ctggtaaacg gggagacgca cacgccgttt tcgtggatgt gcatgccgta
     7381 aaaattactg gagccgggag tcgcgacgtt cggaagaccg aagacttcaa cctccacgag
     7441 agttccttcg tagtctgtgg catagaaccg ggcaagcccg gagatggaag gaaaattgtt
     7501 gccgccggca atccaggcgg atgcatccgg cggagactgc atcagtgtat gaataaaatt
     7561 ggttgctggt gtgatatcgc gcatagctgc ctcaatggaa gagtgttatt ggtttattat
     7621 atgcagcggc ggaaaaatgc gctgcatgtg aggaaagttc catgcataat ttcttgcaaa
     7681 acacaatgta tttgatataa taaaaacatt gggcggatca caattccgca gaagtgagga
     7741 gaagcatgag caatacaaat gacctgagta accgcatcaa tgatgcttac agtaagctga
     7801 gcaagggaca gaaacggctg gcaacctaca ttacggacaa ttatgacaag gcggtatttc
     7861 tgaccgctgc aaagctgggc gaggttgtag gtgtgagcga gtccacggtg gtgcgctttg
     7921 caacgcatct gggatataag gggtatccgg aattccagag tgcgctggag gaactggtgc
     7981 gcaataagct gaactccatt cagcgcatgg aggttactta cggcaggatc agccagtcga
     8041 agattctgga gacggtgctg aaatccgatg cggacaagat tcattccaca ctggaaaaga
     8101 ttgatcagaa cgcatttgaa ctcgcggttg acacgatcct gcacgccaaa catatctata
     8161 tcatcggaat ccggagctgt gcgccgcttg ccagcttcat ggctttttat tttaccctga
     8221 tgtttccgaa cgttcatctg attcagacaa gcagttcgag cgagattttt gaacagatgg
     8281 tgcgcatcgg caaggaggat gtgatcatcg gaatcagttt tccgcgttat tccatgcgta
     8341 ctttaaaggc gatggaattt gcgaataacc ggagtgcgaa ggtaatcaca ctcaccgaca
     8401 gcgtgcattc cccgatgaac ctctattctt cctgcaatct gattgcggac agcgatatgg
     8461 cttccattgt ggattccctg gttgccccgc tgtcggtgat caatgcgctg attgtggcgc
     8521 tctgcatgaa aaagcagaac gaggtggcga aaacgcttga gatgttagag gatatctggg
     8581 acgaatacca ggtttatgag aacgatgaga tcaattatat cgatgattcc atcaagatgc
     8641 ggtatggaaa agtaggagat gcggaactgt atgagtaagg tgatcgtagt cggcggcggg
     8701 ccggcgggaa tgtttgctgc cattgcggcg gcggagcggg gacatgaggt cgttttgctc
     8761 gagaaaaatg aaaagcttgg gaaaaagctc tacatcaccg gcaaagggcg gtgcaacatc
     8821 acgaatgcgg gggatatgga caccctgttt gccaatgtga tgacgaaccc gaagttttta
     8881 tacagcgctt tttacgatta tgacaatcag agagtgattg atttttttga ggagaatggt
     8941 ctggcgacga aggtggagcg cggcaaccgt gtattcccgg tatcggatca ttcttcggat
     9001 gtgatcgcca cgctgcagcg ggtactaaag cgcacgggtg ttatggtgca gcttcatgcg
     9061 gaagtgcggc agatcctcac cggggaaggc gcggtgcgcg gcgtgaagct tgccgacgga
     9121 agcgttcttg aagcagagcg cgtgattctt gcaaccggag gattttctta tcagacgacc
     9181 ggttcgactg gagacggcta ccgttttgcg agggaactcg gacatacggt gacacagatt
     9241 acgccgtcac tggttccgtt ctacgtgaag gagacctgcg cggcgaggat gcaggggctg
     9301 gcgctgaaaa atgtgcaggt gcgcatccgg gacggaaaaa agctgttgta tgacgaattc
     9361 ggcgagatgc tctttaccca tttcggggta agcggaccgc tgattttaag cgccagtgcg
     9421 gcaatcaagc cgggccgcgt ggagaaggaa ctggcgatgg agatcgactt aaagccggca
     9481 ctcacggagg aacagctgga tgcgagactt ctgcgtgaat tcgaggaggc aaagaataag
     9541 cagtttaaaa acgccgtcgt gcatctgttc ccggcgaaga tgattccggt gatgttagaa
     9601 gccggagcga ttgatccgga gaagaaggtc aacgagatca cgagagagga gcggatggga
     9661 tttgtgcatc tgatcaaggc gtttccgctg acgctctgcg gtgtcagaga tttcaatgaa
     9721 gcgatcatca cacgcggggg tgtcagcgta aaggaagtga acccttccac gatggaatca
     9781 aagcttgtgc cgggattgta tttctgcggg gaactattgg atctggatgc gatgaccggc
     9841 ggatttaatc tgcagattgc ctggtcgacc gggcatctgg cgggtgagag tatcgaatag
     9901 aagaggagag aagaagagat gagtatgaat attgcgattg acggaccggc aggcgccggg
     9961 aagagcacaa ttgcgaaaaa actggcgaaa aagctggcgt ttgtctatgt ggatacggga
    10021 gcaatgtacc gtgcgatggc atactatttt ttacagaacg gcattgcacc agatgatgag
    10081 caggcgattg cggcagcctg cccgaaggtt gacgtgacga ttgtgtatga gaacggcgaa
    10141 cagcaggtgc tcttaaacgg agagaatgta aacggcgtca tccggacgga ggaagtcggc
    10201 aatatggcat cagcgaccag tgtctatccg gttgtgcgca caaagcttgt ggaactgcag
    10261 cggcagcttg cgacaaagac ggacgtcatc atggacggaa gggatatcgg cacctgtgtg
    10321 cttccggatg cgcaggtaaa aatatatctc acggcaagcg ttgcaacgcg cgcaaagcgc
    10381 agatatgatg aactgaccgc caagggaacc cagtgcaatc tggaagagat cgagaaagat
    10441 attgaagacc gcgattaccg cgatatgcac cgggagacat cgccgttaaa gcaggccaag
    10501 gatgcggtgt tagtggacag ctccgagatg aacatcgacg aagtggtgga cgcaatctat
    10561 cagatttatg cgagggtata gagaatatga atgtaatctt ggcaaagagt gcgggcttct
    10621 gcttcggggt aaaacgtgcc gtggatacgg tatatgaacg gattctggaa aaagaaccgc
    10681 tctacacgtt cggaccgatc atccacaatg aagaagtggt gcgcgatctg gaggaaaagg
    10741 gcgtcgtcgt ggtaaacgat gtggacgaac ttgcggggaa gccgcagggg acggtaatca
    10801 tccgggcaca cggcgtggag agaggtgtct gcgagaaaat acagacgctc ggcttttcca
    10861 tcgtggacgc gacctgcccg tttgtgttaa agattcaccg gctggtggag cgctacagtg
    10921 gggaggactg tcacattgtg atcgtcggga atgccagcca cccggaggta aagggcatca
    10981 aaagctggtc gaatgcagag gatacgcgcg tgatcggaac ccgcgaagag gccgaaaaat
    11041 acgatgcttc ccatggaaaa aaggtatgta ttgtatcaca aacgacattt aattacaata
    11101 aatttcaaga attagttgaa attataaaag aaaaaggtta tgatataatt gttttaaata
    11161 caatctgcaa tgctacggag gaacgtcaga cggaagcccg ggcaatcgcg gagcaggtgg
    11221 atgccatgat tgtgatcggt ggcaggaaca gctccaacac gcagaagcta tttgaaatat
    11281 gtaaaaacga atgcaaaaat acttactata tacaaactgt aaaggatctt gaccttgccg
    11341 aagtcaggtc tgtcgataac gtaggtatta ccgcaggggc ttctacccca aacaatatta
    11401 ttgaggaggt tcaaaagaat gtcagaaatg ag
//
