LOCUS       c00075_gnlPro..        13803 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EJOFABDF_75.
ACCESSION   c00075_gnlPro..
VERSION     c00075_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:16:39
            Original ID  :: gnl|Prokka|EJOFABDF_75
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13803
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13803
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5075:13490]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5076..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13803
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13803
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             333..821
                     /locus_tag="ctg75_1"
                     /transl_table=11
                     /translation="MPKNKFQEVIFTIIMVFVMVYAMICYNIVLNTGTMTNETFLLAFH
                     ELTFMGPIAFILDFFIIGGLAKKIAFGVVDMRRDNPFHLVLAISAVSVAFMCPCMSFAA
                     TVLIKHAPASQIIPTWLQTTAMNFPMAFFWQIFYAGPFVRFIFGKLFPEKEKAAASAE"
     CDS             1175..2173
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1044:Bacterial extracellular solute-binding protein
                     (Score: 56.8; E-value: 1.2e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_2"
                     /sec_met_domain="SBP_bac_1 (E-value: 3.1e-18, bitscore:
                     56.8, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKLFAFGLAVVLALMPVQTFGKTVSITNVSYDPTREMFEQYNK
                     IFEDHWKEKTGEDVEVIQSHGGSGKQALEVANGLDADVVTLALEYDIESIENAGLIKAG
                     WKDKFDNDSSPYTSTIVFLVKKGNPRDIKDWDDLTKKGVGVVTPNPKTSGGARWNYMAA
                     WAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFVENGQGDVLVAWENEAYLS
                     MRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRDTRDVATEYLNYLYSDEAQEIAAENY
                     FRPTNEKILKKHSDTFDLNINLANISDYGGWDKVQKKHFTDGGIFDQIYER"
     CDS             2244..3080
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 83.5; E-value: 5.1e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg75_3"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.3e-26, bitscore:
                     83.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKPVIPGFGLSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     FIETITRARVLASFYTSFVCAFAAAVINGIMGTILAWVLVKYDFPGKRLMDGMIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFGIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNA"
     CDS             3080..3904
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 59.7; E-value: 1e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg75_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.7e-19, bitscore:
                     59.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSEKITKWLLVGISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATLFAVVFNTVFGVFAAWALTKFQFRGKKLLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMNLGIKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVVRSLIEYKGKKEA"
     CDS             3906..4964
                     /locus_tag="ctg75_5"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLETPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDARVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGRIEQKGTPIGVYR
                     NPETAFTASFFGQPSVLKNADDFHTFAQAEGADKIIVRPEFVKISKLDEVEKFKTSVSR
                     GVVERVSFRGDNLELQVRVNNSVVTARRSLEKADIREGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             5076..6821
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 71.4; E-value:
                     2.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.9e-23, bitscore:
                     71.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.5e-08,
                     bitscore: 24.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRVPQDYVDYAKKDAHGIVREDLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAHGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKEEALERGGEQELSQTAIAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSGMSLAKADEKIAALLPVVDTLAATDTYELMQIYELRERLIVCQAVIA
                     HLAARKETRWHSFGENTDYPQQSEEWMKYVNSRMENGEIKILYRDLITKENTGLNTAEK
                     GAGKR"
     CDS             6818..7132
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_7"
                     /sec_met_domain="Fer4_9 (E-value: 2.1e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.1e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-05, bitscore: 14.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKPDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             7163..8281
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_8"
                     /sec_met_domain="PAPS_reduct (E-value: 4.8e-65, bitscore:
                     208.9, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTICGRFCSDEGVVAGYDNRIRTKYTAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNLSHLDALEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKENGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERPVIYRDGNIIMVDDDRLKLRPGEEIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKREGYF"
     CDS             8283..9923
                     /locus_tag="ctg75_9"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYTDQEKALELDSKV
                     GSRGGAIDYSLLLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIKNQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMPWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGAIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVSRGCVLTIDSGAVLTDSVEADILWMDDNALTDGKNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILIDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEGITLDFAEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLIVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVHDGNYI"
     CDS             10068..10364
                     /locus_tag="ctg75_10"
                     /transl_table=11
                     /translation="MQTNNESKQNQKRDDAWNFVCNCYDHHPGDTNEEKTEIKMSEYRS
                     ECRMGNWLLFTHHYPARCFGMNMPKSRDIQAKIPLPQAIWNEFWLSYYERSEQ"
     CDS             10592..10846
                     /locus_tag="ctg75_11"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             10819..10947
                     /locus_tag="ctg75_12"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELRYVKSNVSITAEGNDIYEKI"
     CDS             10925..11707
                     /locus_tag="ctg75_13"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLAACIAAVCMFSDVHGAEVAGPPAPKSKSALT
                     QKPEATPMPEATPIPASTPTPEQETETDKQNPADQGTLSKPDHPDTISADKLVFIGDSR
                     TEGLRDAVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYI
                     SYINSKAAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQASLSGVTYIDVYSHL
                     VSEGFSTVDGTHYPDSVSVDIYNYILDHLEEQMSGIWG"
     CDS             11973..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_14"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.7e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.8e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     TYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTIM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFHASADGRGFA
                     VSGGVAEAVVHAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEASFTDAYDSKYRARLESLEKFDVE"
     CDS             13429..13554
                     /locus_tag="ctg75_15"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKAWRNLMWSEILTESVKSYMDCKCLNAISI"
     CDS             complement(13662..13802)
                     /locus_tag="ctg75_16"
                     /transl_table=11
                     /translation="RDGNRTYNADAVGAYNILRKYHSVSGVKRELSVTGLKTPEIIKVA
                     V"
ORIGIN
        1 actgttcact ccgttcacag taacgtagcc aaaattcatt ccagattgcc tgcggcaatg
       61 gaattttggc ttgtatgtct cgggattttg gcatattcat gccaaaacac ctcgcgggac
      121 agtggtgtgt gaacagtaac ctttgtttcc tgattcacac tgcaggtact gaaaaaatcc
      181 ttgacttttt ttaaaacagt ccgtataata accaacggta aatttaagaa acagatattt
      241 ggtattattg gaaacggtac atcctcctgg atggttatga acaacacaaa tctctaattg
      301 atgttattca tactatctaa ggaggatttt ttatgcctaa aaacaagttt caggaagtta
      361 tttttacgat tatcatggtg tttgtaatgg tttatgccat gatctgctac aacattgtac
      421 tgaacacagg gacaatgaca aatgagacat ttctgttagc ttttcatgaa ttaacattca
      481 tgggaccgat tgcatttatt cttgatttct ttatcatcgg tggtcttgca aagaagattg
      541 catttggtgt tgtggatatg agaagagata atccgttcca ccttgtactt gcaatctcag
      601 cagtatccgt tgcatttatg tgtccatgta tgagctttgc ggcaactgtg ctgatcaaac
      661 atgcaccggc aagtcagatc attcccacat ggctccagac aacagcaatg aactttccga
      721 tggcattctt ctggcagatc ttttatgccg gaccattcgt aagatttatt ttcggaaagc
      781 ttttcccgga gaaagaaaag gcagcagctt ctgccgaata aaaaatatat aattttgact
      841 gcagcattct gtatttcagg atgctgcttt ttttgtgttc ttatctatac gttactgttc
      901 actccgttct cagtaacgta gccaaaattc attccagatt gcctgcggca atggaatttt
      961 ggcttgtatg tctcgggatt ttggcatatt catgccaaaa cacctcgcgg gatagtgatg
     1021 tgtgaacagt aacatctata caacgtaaat tgtacttatt ttaatacact attgacaaat
     1081 tctgtcattt cttgtaatat catataaaac atatcgaata actatgaaaa gtagagaatg
     1141 caaaaaacta ctggtacctt aaaggagatg aaacatgatc agaaaattat ttgcctttgg
     1201 tcttgcagtt gtactggcac tgatgccggt acagactttt ggaaaaacgg tgtctatcac
     1261 taatgtttcc tatgatccta ccagagagat gtttgaacag tataataaaa tatttgaaga
     1321 ccactggaag gagaagaccg gggaagatgt ggaagtgata cagtcccatg gcggttcagg
     1381 gaaacaggca cttgaggtag ccaatggtct ggatgcagat gtggtaaccc tggcactgga
     1441 atatgatatt gagtctattg aaaacgcagg gttgatcaag gcaggatgga aagataaatt
     1501 tgacaatgac agttctcctt atacatccac tatcgtattt ctggtgaaga aaggaaatcc
     1561 cagggatatc aaagactggg acgatctgac gaaaaaagga gtgggagtag taacaccaaa
     1621 tccgaaaacc tccggcggtg ccagatggaa ctacatggca gcgtgggctt acgcagataa
     1681 aaagtatggt ggcgatgaag cgcagatgaa ggaatttatt aagaaacttt atcggaatgt
     1741 ggtggttctt gactcaggcg caagaggcgc aacgacctct ttcgtggaga acggacaagg
     1801 agatgtgctg gttgcgtggg aaaatgaagc ttatctatcc atgcgggatt atccggatga
     1861 gtatgagatt gttactccaa gcgtaagcat tctggcacag ccttctgtgg cggtggtaga
     1921 tgaagtggtg gattacagag atacaagaga tgtggcaact gagtatttga attatctgta
     1981 ttccgacgaa gcacaggaga tcgcagcaga gaattatttc cgccccacca atgagaaaat
     2041 tctgaagaag cacagtgata cgtttgatct gaatataaat ctggcaaata tcagtgatta
     2101 tggcggatgg gataaagtgc agaagaaaca tttcacagat ggcggaattt tcgatcagat
     2161 ttatgagaga taaaggaaga caagatgaag caggagcata agcacagaca gaatatatga
     2221 gacaggagag gtggtaattg attatgaaaa aaagaaataa accggtgatt ccagggtttg
     2281 gactctccat gggaattacc atttccatat tgagtctggt agttctgatc cccctggcaa
     2341 gtctggtggt ctacacagcg aagctgagtt ttaaagattt tatcgaaacc atcacaaggg
     2401 ccagagtgct ggcatccttt tataccagtt ttgtatgtgc ttttgcagca gcagtaataa
     2461 atggaattat gggaactatt cttgcgtggg tgcttgtgaa atatgatttt ccgggcaaga
     2521 gacttatgga tgggatgatc gaacttccct ttgctcttcc cacagcggta gcaggtattg
     2581 cgctgacatc cctgacctca gattccggaa ttgtaggcag cttttttgca ggattcggta
     2641 tcaagatcgc atacacaaga atcggcatta cagtggctat gatatttgta gggataccgt
     2701 tcgttgtgcg aagtgtacag ccggttctgg aaaagatgga taattcttac agcgaggcag
     2761 caggagtgct gggagcaaag aaaacaacta tcttctggaa ggtcattttt ccggaactga
     2821 agcccgcgat ctttgcaggg accggacttg cgttcggaag atgtctgggt gaatatggaa
     2881 gtgttgtatt tatcgcagga aataaaccct attatacaga aatcacaccg ctggttatta
     2941 tgtcagagct tcaggaattt gattattcaa gtgcaacggc aatcgcactt gtgatgttgg
     3001 cagtttcatt tttcattctg ttccttaaca gtatgataca gcagagaaat gcaagaattt
     3061 taagaggagg aaatgcctga tggacaacaa tgaaaagact tcggagaaaa ttacaaaatg
     3121 gctgcttgtc gggatcagtg ttttgtttct ggcagtcatg ctccttcttc ctctgatcac
     3181 tgtgatcaca gaagcattgc ggagcggatg gaaggtctat gcagctgcag tgacagatga
     3241 gtacaccatc aaagcacttc ttcttacagt gaaggcaaca ctctttgcag ttgtttttaa
     3301 cactgttttt ggtgtttttg cagcctgggc actgacgaag tttcagttca ggggtaaaaa
     3361 gcttcttacc acactgatcg atcttccggt tactatttcc cctgttattg caggtctgat
     3421 ctttcttctg atttttggac gacagagtcc tgtttacttt tttctcatga atttagggat
     3481 taaagttgta ttctctgtac cgggaatcat tattgcaact gtatttgtaa cctttccttt
     3541 tatttccaga gaactgattc cggttctgga agcagaagga agcgatgagg aggaagcagc
     3601 agccctgatg ggagcaggtg gatggaccat tttctggaag atcacattcc ctcatatcaa
     3661 atgggcatta ctgtacggag ttgtgctctg tacggcaaga gcaatgggag agtttggagc
     3721 ggtatctgta ctttccggac atttaagagg aaagaccaat acacttcctc ttcatgtaga
     3781 gattttgttt aatgagtttc agtatgttcc ggcgtttgcc gtatcttcgc tgcttgtgat
     3841 catggcagtt atcattctgg tagtcagaag cctgattgaa tataaaggaa agaaggaagc
     3901 ctgatatgta tgtagagtta aaaaatatca ataagacata tggttcttac caggcatcaa
     3961 ggaatgtgaa tttcggaatt gagaaaggta aactgattgg tctgttggga ccaagcggaa
     4021 gcggaaaaac aactattctt cgaatgatcg caggtctgga aaccccggac agcggagagg
     4081 tcattattga tggaaaagtg gtaaatgatg ttccggccag tcagcgtggg attggatttg
     4141 tatttcagaa ttatgcgttg tttcgctata tgacagttta tgacaacgtt gcatttggtt
     4201 tgaaggttca gaaggctgat aagaagaaaa ttgatgccag agtcagagag ttgatcaaac
     4261 tggtggggct ggaaggactg gaaaaaagat atccaagcca gttatccggc ggtcagaggc
     4321 aaagggtggc atttgccaga gcccttgctc caaatcccca ggtgctgctt ctggatgagc
     4381 cctttgcagc cattgatgca aaaatccgtc aggaactgcg aagctggtta aaagagatga
     4441 tcgggaagct gggaattacc agtattttcg ttactcatga tcaggatgag gccattgaag
     4501 tagcagatga gattattatc actaatgcag gacggatcga acagaaagga actcccatag
     4561 gggtttatag aaatcctgag acagctttta cagcgtcctt cttcggacag ccatctgtgt
     4621 tgaaaaatgc ggatgatttc catacctttg ctcaggcaga aggagcagac aagatcattg
     4681 tccgcccgga atttgtaaaa atctccaaac tggatgaggt ggagaagttc aaaacttccg
     4741 tatcccgggg agtggttgaa cgggtttctt tcaggggaga taatctggaa cttcaggtga
     4801 gagtcaacaa ttccgtagta actgccagaa gaagcctgga gaaagcagat atccgggaag
     4861 gtgagactgt gaatgtattc ctttacagga tttttgcact gagaggtgac agtgtacagc
     4921 tgatcgaaaa tgaggctgta agggatgact ttgtaattat ctgacagcgg tggctgcggc
     4981 gactgacgac aatgaagaaa taagaaattc agaggcaaga ctgatcggaa aatcaacttg
     5041 ttggcacact ggtatggagg aaagggtaag agagaatgag aacagagaga atcaggacag
     5101 atgtgctgat catcggcggc ggtacggcag gatgctttgc agcctatgtg atcggcaaaa
     5161 aaagcggcag aaaagttctg atcgcagaga aagcgaatat taagcgaagc ggatgtctgg
     5221 cggcgggcgt gaatgcattg aacgcatata ttacagaagg cagagtgccg caggattatg
     5281 tggattatgc caaaaaggat gcccatggaa tcgtaagaga agaccttctt cttaccatgt
     5341 cagagagact gaatcatgtg acaaaggtga tggaagatct ggggctggtc atcctgaagg
     5401 acgaaaacgg aaaatatgtt gccagaggaa accgaaacat caagatcaat ggcgaaaata
     5461 tgaagccaat ccttgcaaag gcggcagctg aacaggagaa tgttacggtt ctcaatcatg
     5521 taaatattac agattataaa acagaaaaca aaaaagtcac aggcgcagtt ggatttagcg
     5581 ttaatgagga tattttctat gacattgatg cgaaagcagt tctttgtgcc acaggtggtg
     5641 cagcgggact ttacagaccg aataatccgg gattttccag acataagatg tggtatcctc
     5701 cgtttaacac aggtgcagga tatgcaatgg gacttctttc cggtgcggag atgacaacct
     5761 ttgagatgcg tttcattgca ttgagatgta aggacacgat tgctcctaca ggaactattg
     5821 ctcagggtgt tggggccaga caggtcaatg cacatggtga tatttatgaa acaaaatatg
     5881 gtctgacaac ttcccagcga gtttacggta cagtcatgga gaacagagaa ggaaacggcc
     5941 catgttatct cagaacggaa ggtatttcca aagaacagga gcaggacctt tacaaagctt
     6001 acctgaatat ggcaccgtcc cagactctga aatggatgga agccggaaaa ggaccatccg
     6061 aagagaatgt agagattgag ggcacagagc catatattgt aggcggacat acagccagcg
     6121 gttactgggt agataataac agagctacaa ctattgaagg tttatatgca gccggagacg
     6181 tagcaggagg atgtccgcag aaatatgtaa ccggcgcact ggcagaaggt gagatcgcag
     6241 cagaggcgat tttggaatat ctgaatggca aagatgatga ccggatcgca gcggaaaata
     6301 aggaagaggc tttagagcgt ggcggagaac aggagctgtc tcaaactgca atagctaaga
     6361 aggcagaata cgaatcacat ttgaatgctt cccgttcttt gatgaatgca gagcagcttg
     6421 aggaagccat gcagaagatc atggatcagt acgcaggagg aatcggtaca gactacagat
     6481 acagcgggat gagtcttgca aaggcagatg aaaagatcgc agcattgttg ccagtagttg
     6541 acactctggc agcaacagat acttatgaac tgatgcagat ttatgaactt cgcgaacgac
     6601 tgatcgtgtg ccaggcagtg atcgcacatc tggcagccag aaaggaaacc agatggcata
     6661 gtttcggaga gaatacagac tacccgcagc agagcgaaga gtggatgaaa tatgtaaact
     6721 cccgtatgga aaacggcgag attaagatct tatatcgtga cctgatcaca aaggaaaata
     6781 caggtttgaa tacagcagag aaaggagcag gtaagagatg agcattcgga ttcagaaaag
     6841 taaatgtgca ggatgcggca gatgtatcga agcctgtccc ggaaatctga tcaaaaagga
     6901 taaagagaac aaagccttta tccgtcaggt aagagactgc tgggggtgta cttcctgtat
     6961 taaggaatgc aggcatgatg ccatccgctt tttccttggc gctgatgtgg gaggcagagg
     7021 tgcaagtatg gttgtatcag agaaaccgga tatttccaca tggacagtgg agaagccgga
     7081 tggcactaag atcactattc aggttaataa gaaagacgct aataaatatt aaacataagt
     7141 atgtactctc agagtcttta gagtgtgttt gaaaaatgct ttacgcaaga tgtgcgtcac
     7201 aatttgtggg agattttgtt cggatgaggg cgtcgtagcg ggctacgaca accgaattcg
     7261 gacaaaatat accgcaaagt ggggcgtgca gattgcggga atgatttttc agacacgctc
     7321 tagtgtattt gctcaagtac gaaaagattc cgagtataaa caaacagagg aggataatgc
     7381 aatgagtaac ttatctcatc ttgatgcgct tgaggcagag gcgatttata ttatgcggga
     7441 agtagcagcc gagtgtgaaa agccggttat gctctattct ataggaaagg acagctccgt
     7501 tatgctccat ctggcgatga aggcatttta cccggagaaa cctccattcc cgttccttca
     7561 cattgatact acatggaaat tccatgagat gatcgaattc cgcgacagaa tcgcaaagga
     7621 aaacggaatt gatatgctgg tttacaccaa tgaagagggt gtaaaggcag gaatcaatcc
     7681 atttgacaat ggttctgcat atacagatat catgaaaaca caggcgttaa aacaggctct
     7741 gaccaaatat ggatttacag cggcatttgg aggcggccgc cgtgacgagg agaaatccag
     7801 agcaaaagaa agaatcttct ctttccgtaa ttcagctcag gcatgggatc cgaaaaacca
     7861 gagaccggag atgtggaagc tttataacac taagatccag aagggagaga gtatgcgagt
     7921 attcccaatt tccaactgga cagaaaagga tatctggcag tacattcagc gtgaaaatat
     7981 cgaaattgta ccgttatatt ttgcaaaaga aagaccggtc atctacagag atggaaatat
     8041 cattatggtg gatgatgaca gattaaaact ccgtccgggt gaagagattg aaaacaaaaa
     8101 agtcagattc cgtactcttg gatgctatcc gcttactgga ggtattgaat ctgaagcaga
     8161 tacgctggat gagattattg atgagacgtt aagtgctgtt tcttctgaac gtaccagcag
     8221 ggtgatcgac cacgaggcag caggcagcat ggagagaaga aagagagagg ggtatttcta
     8281 gaatgaaagg attattgaaa tttattacat gcggaagtgt ggatgatgga aaatccactc
     8341 tgatcggaca tattctttat gatgcaaagc ttctctatac agatcaggag aaagctctgg
     8401 agctggattc caaagtagga agcagaggcg gtgccattga ttattctctt cttctggacg
     8461 gtctgatggc agagcgtgaa cagggaatca ccattgatgt tgcataccgt tattttacaa
     8521 cagataacag aagcttcatt gttgcagata cacccggaca tgaagaatat acaagaaaca
     8581 tggcagtggg tgcgtccttt gcagatctgg cagttatcct ggtggatgct tcacagggag
     8641 tactggtaca gacaagacgt catgcaagaa tctgcgcatt gatgggaatc cgttactttg
     8701 tatttgcagt aaacaaaatg gatcttattg aatatgatga aaaacgtttc cgcgacatta
     8761 agaatcagat cgcagcactg atagaagaac tgaaacttgc caatgtaact attattccgg
     8821 tatctgccac agaaggtgac aacgttacaa ccaaatctga caacatgcca tggtataaag
     8881 gtgaggcgct tctttcccat ctggaaaccg tagacattaa ggaagataca gagaagggct
     8941 tctatatgcc tgtacagaga gtctgcagac caaaccatga gtttcgcgga ttccagggac
     9001 agattgaaaa tggtgccatc agggcaggcg accttgtgac tactcttccc agtaaagaag
     9061 aagctcatgt aaagagtatt cttgttggcg ataaagaagt tcaggaagct gtacagggac
     9121 agcctgttac catccagctt gacagagaag tagatgtttc ccgcggatgt gtacttacca
     9181 ttgattccgg cgcagttctt acagattctg tggaagcaga tatcctctgg atggatgaca
     9241 atgctcttac ggatggcaag aacttctttg taaaaatcgg tacaaagatg atccccggac
     9301 tggttacaaa gatcaattat tctgtggatg ttaacacagg tgagaagaaa agcgcatata
     9361 ccttaaagaa aaatgagatt gcttcctgta ctctggaatt ctcagagaaa atcgttgtgg
     9421 acgaatttga caggcacaga acactgggtg agctgatcct gatagatcgt gtcacaaata
     9481 tgacttctgc ctgcggtgtt gtgagaaaaa cctttgtttc tcaggataga tcccagatcg
     9541 gaaaagtgga cgagcaggtt cgtgcaggac tgaaaggtca gacaccggta gtagtggaat
     9601 tcccgatcgg taaagaagga atcactcttg attttgcaga gcaggtagaa aagggactga
     9661 ctgtacttgg aaaacatacc tatctgtatc atccggcagc gagtgaaaac tatgcagaaa
     9721 ctgtccgcca tcttaaggca gcaggtctga tcgtacttct tgttcttgat gaaaatacag
     9781 caaaagacga gacattaaag actctggatg gtttctatgc gaactggcag attgacggaa
     9841 tcactgtgaa agatgcgatt gatttcgtga aaaagaaatc tgcatttaca gtgcagagtg
     9901 tacatgatgg aaattatatc tgattataac agggctataa atcgccgcag agacaaagaa
     9961 agtctctgcg gtattttgtt ttcttgacaa gtgtcgttac agcagattat acttattctc
    10021 aaatattcag aatccataat aatacagaca ggaaagataa cagaaatatg caaacgaaca
    10081 atgaaagtaa acaaaaccaa aaaagagatg atgcttggaa ctttgtttgt aattgctacg
    10141 atcatcatcc tggcgatacc aacgaagaaa agacagaaat aaagatgagt gaatatcgat
    10201 cagaatgtag aatgggcaat tggttactgt tcacacacca ttatcccgcg aggtgttttg
    10261 gcatgaatat gccaaaatcc cgagacatac aagccaaaat tccattgcca caggcaatct
    10321 ggaatgaatt ttggctaagt tactatgaac ggagtgaaca gtaacggcaa ttgtgaagtg
    10381 gcattcagat tacatattat gcagcagagt atgatataat tcgttttgta taatggcgtc
    10441 aggattaaga gcatatgtag agctgtgtag cgaagcggat tgcgaatatc tgtttgactt
    10501 ttgatgggtg tacacgagaa cattttttta cagtgaaagt tatctgtatt atattacaga
    10561 aggtactgta cagataatca ggaggtattt tatgcgtttg gaaaaagtac aggaagcgtt
    10621 aaaaacaaag aaaattcatt atgaatatac agaggaaaat ggatgcggaa gcatcgactt
    10681 tatgtttcgc ggtctgagat tccatatatg ggaatatgaa gatcgtgtct ggggagcgga
    10741 gacaaacgtg ttcgaagcag gcagaagcca ggatattgaa ggagattacg aggaaattat
    10801 ttccggagaa atcctctcat ggccggatat gctgcctggg atgtaagtat gttactgttc
    10861 acagcaacac actccaggga gttgagatat gtgaaaagta acgtaagtat tactgcagaa
    10921 gggaatgata tttacgaaaa aatatagaac cggacaaatc gtattagccg catgtattgc
    10981 agctgtctgt atgttttcag atgtccatgg ggcagaagtg gcaggtccgc cggcaccgaa
    11041 atccaaatcg gcactgacac aaaaacctga agcaacacca atgcctgaag caacaccaat
    11101 acctgcatct actccaacac cggagcagga aactgagaca gataaacaga atccggcaga
    11161 ccagggaact ttaagcaagc cagaccatcc ggacactatc tccgcagata aactggtatt
    11221 tatcggagat tccagaacag agggattgag ggatgcggta aacgatgaca gcatttggtc
    11281 ctgtctttct tctatgggat atgactggat ggtatctaca ggagtgccgc aggtagaaga
    11341 tcagattgag gacaatacag cggttattat cctgatgggt gttaatgatc tttatcatgt
    11401 caatgactac atcagttata ttaattccaa agctgctgaa tgggggaaca gaggagcgca
    11461 gacttatttc gtgtctgtag gtccggtgca gaatgatccc tattgcagta atgcggagat
    11521 tgaaagtttt aacgcggcaa tgcaggcaag cctgagtgga gttacctaca tagacgtata
    11581 ttcccatctg gtatctgagg gattttccac cgtagacgga acccactatc cggacagtgt
    11641 gtccgtagat atttataatt atatcttgga ccatctggag gaacagatga gtggaatctg
    11701 gggataacaa catatgaaca gcaacttcgg gggcgacaat tcagcgaaaa ttctgatgtt
    11761 gtgttgagcc tggaagcatt tggtgatatg atatgcagat aaggaaacgg aaatgagcgg
    11821 aatttcgttt ctctgtgaag tggctgaaag ttcagcagga ggaaaaatga gtgtgctgat
    11881 tgcagcagtg atgaaattat aaatggaaat tgttcggtgt ccctgcattg gattgccgta
    11941 cagttatccg aatcgaaaat caggaggaaa aaatgagagg actgtattca tccaaaacag
    12001 aaatcagaca caaaattttt acagaaattg cgaggatggc atatgaaggc cagtctccgg
    12061 agatgctgga agagcttccc tacaagatcg tacccggtga aattgcgact tatcgtgaca
    12121 gtatttttct ggaaagagcg gtagttggtg agagacttcg cgttgcaatg gggatgtcac
    12181 tgagaaaggt tacagagcat gcgccaattt ccaaaggtgt ggaggccagc gttattgagg
    12241 aaaagtatta tgaaccgccg cttatcaatg tgatcaagtt tgcctgtaat tcctgccctg
    12301 aaaaaagggt aatgatcaca gagggctgtc aggggtgcct ggagcatccc tgtgtggaag
    12361 tctgtccaaa gaaagcagtg catatggaag gcggcagatc ccatattgat gaagatgcct
    12421 gtatcaaatg cggaaagtgt ctggaagcct gtccgtataa tgcaatcatc aaacaggaac
    12481 gtccatgttc aaaggcatgc ggtatgaatg ctattggctc tgatgaatat ggaagagcag
    12541 agattgatca ggataaatgt gtatcctgcg gacaatgtct ggtaagttgt ccgttcagtg
    12601 ctattgtaga caaaggacag attttccaga ctattatggc attaaaaagt gaaacaccgg
    12661 tgtatgcaat cgtggcgcct gccattgcag gccagtttcc gggtatggag aataataaga
    12721 tacggggagc atttcaggca cttggcttta cagatgtaag agaggttgcc gtcggtgcag
    12781 atctgtgcac agtggaggag gcaaaggact ttttggaaga agttcctgag aaacttcctt
    12841 tcatggctac atcctgttgt ccgtcctggt ctatgatggc taagaaatta ttcccggaac
    12901 aggcgaaatg tatctctatg gcactgacac ctatggttct cactgcaagg ctgatcaagc
    12961 agaaggaacc agattgtaag atcgttttcg taggtccctg tgcagccaag aagctggaag
    13021 ccagccgtaa gagtatccgc agctatgtgg attttgtgct gaccttcgag gaagtagcag
    13081 gaatgtttga tgccaaaggc gtggactgga aagatattcc ggaaggagaa ccactgtttc
    13141 atgccagtgc tgacggaaga ggtttcgcag tcagcggtgg tgtggcagaa gcggttgtcc
    13201 atgcggtgaa gcgtattgat cctgatcggg aagtaaaggt aatgaatgca gaaggtctgc
    13261 agaactgtaa gaagatgctc cagatggcca agattggtaa atataatgga tatcttttgg
    13321 aaggaatggc atgtccgggc ggctgtgtag caggtgccgg tactatccag acagttaaaa
    13381 aagcagcagc agctctcgaa aaaatgaaga aagaggcttc gtttacagat gcctatgact
    13441 ccaaatacag agcaagactg gaaagcctgg agaaatttga tgtggagtga gattctgact
    13501 gaatcagtga aatcctatat ggattgcaag tgtttgaatg caatcagtat atagcagagt
    13561 gaattactcg gcaactgagt taccagagca tctgaattaa ggcgggatac cgcctttttt
    13621 cagggtgcat ccatgacacc actactgttt gctctttaga gttatacagc tacttttatt
    13681 atttccggtg ttttcagtcc ggttacggac agttctcttt ttactccgga tacggagtga
    13741 tattttctca ggatattata tgcgcctacg gcatctgcgt tataggttct gtttccatct
    13801 ctg
//
