LOCUS       c00071_gnlPro..        12799 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHAHOFNO_71.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:45:53
            Original ID  :: gnl|Prokka|BHAHOFNO_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12799
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12799
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2885:11673]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2886..11673
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12799
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12799
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..1103
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="LTLDPTPAAVPQEEKPAAAPAPEAQVNLTPEEQAMVDQFAQKIDI
                     TNSQQVLQYGSACQKKIGDFSEAALSKVSTKDLGEVGDMITDLIGELKSFDANEEQQKG
                     IMGFFKKKTSQLDALKTKYDKTETNVEKIQSMLEAHQVQLLKDIAMLDKMYELNMAYFK
                     ELSMYILAGKKKLADVRANELQQAMDKAKVSGLPEDAQAARDLADQCERFEKKLYDLEL
                     TRNISLQMGPQIRLLQNNNTMMAEKIQSTIVNTIPLWKNQMVLALGLAHSQQAMQAERA
                     VTNMTNDLLKKNAEALKLGTIETAKESQRGIVDIETLQQTNKSLIETLDELNKIQSEGR
                     AKRAAAEQELTRIEDELKTKMMEIRS"
     CDS             1105..1863
                     /locus_tag="ctg71_2"
                     /transl_table=11
                     /translation="MANADFSQNKQTAPGGFDAGSYREKAKPEQTVRLTPRQQKLAALE
                     AKLPAALSTRAAALALSVVVMLVAFFGFGSAKLRGKYNTARQWFTAGVAADNGYNLSEE
                     LTTRENTAANILTTASNTLGADSAEVLAAQTALNDFSACLQAVQNGGKSQSLTSLPYYQ
                     GSTMHALYQADQALGAAIDQLYAKLQEQAADPMKMGAVQGQYGQFNSAATIIGTLQYNT
                     AVYEYQKDVGGFPAGVLGAVAGVKEVEPFA"
     CDS             1860..2741
                     /locus_tag="ctg71_3"
                     /transl_table=11
                     /translation="MKNFAKRISALVLAVVVSAAVLCPAAFAAQLPSLPKDQCVVDDAG
                     VLSSSTVQTITELNAQLESSCSGAQIGVLTVEYTGNDSTEDYAVQAANAWGIGSSTGKN
                     GVLILLVMETQQYADGDYYIATGDGFRNTTLEKQASAIAQTMEDQFAAKDYDGAVTTCA
                     RNVANTIADIYGVSLSGSAGNGSTVQPGHQGSQSSGGSALTDILTLVVSVVLLIVIIRS
                     VAYVFASPCGWLWCFGGPRPPRGGGFGGMGGGSFGGGAGRGGFGGGSFGGGGSFGGIGG
                     GSFHGGGGGRGR"
     CDS             2886..4091
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="PALP (E-value: 3.1e-94, bitscore: 305.1,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLDKIYHAAFVLKDVARKTDLIEAPKLSKDCQLYLKTENLQAT
                     GSFKVRGAYYKISQLSEEESAKGVIACSAGNHAQGVALAATRRGIRSIVCMPDGAPLMK
                     VENTKNLGAEVCLVPGTYDEAHDKAVQLQKEYDMTFIHPYDDEQVIAGQGTIGLEILDQ
                     LPDVDAVVVPVGGGGLISGIAFAIKTLRPEVKVYGVQAEGAPSMYRSLHEHKYQTLKSA
                     STFADGIQVKTPGELTYQLCEQYVDDIVTVTEDETAAAILSLMENQKLVAEGAGAVPVA
                     AVLFHKLPVEGKKVACVISGGNIDVNILNRVITRGLVMSGRKANLTIALEDKPGQLKKV
                     AEVVSRCGSNVVSVQHDGSDPNMPISSCFLKLTLETRDAAQIEQIRTELTKAGFQLVSE
                     RV"
     CDS             4279..4653
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ribonuc_L-PSP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1038:Endoribonuclease L-PSP (Score: 150.2; E-value:
                     8.5e-47)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="Ribonuc_L-PSP (E-value: 1.5e-47, bitscore:
                     150.2, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVSTANAPAAIGPYSQALDLGNMVFVSGQIPVDPATGTMADTV
                     EQQAAQSLANLKAILAEAGLSMNNVVKTVIFLADINDFAAVNAEYAKAFAEPFPARSCV
                     QVAAIPKGAKLEIECIAVRD"
     CDS             complement(4742..5959)
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MKLREWNAHLHGLVVFRALLNDPVVAKLLDLTDRMEAGCSSYGPV
                     CDAVAAFEAALFEYTTNWGSYLSNAVLEAETICVRQAAAGQLDALLQSALDSELQFLQQ
                     LCGLTLDELFQTAYSEQAQRPELAFLPQWQTCELDLAAAYAQRMSEVGKKGYGMFAKHY
                     VFTVENGQLVPVKYPDPQRLSELPGYEKEREKVIANTKALLAGMPANNVLLYGDAGTGK
                     SSAVKAIANEFASGGLRLVEVKKNQLYQIPDLMDKLAANPLKFILFIDDLSFTANDDNF
                     AALKAILEGSVGGRAQNIAVYATSNRRHLIKETLSDRTGDDIHEADTRQELMSLSARFG
                     LTVTFQRPEKARFETILEELAKQHNIQMPTEQLLLKAEAFALRAGGRSPRVAKQFIEQC
                     EAGVQK"
     CDS             6486..8150
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-51, bitscore:
                     163.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLNGSQIFVEVLCEQGVDTLFGYPGGAVLNLYDELYKNADRITH
                     VLTAHEQGAAHAADGYARATGRTGVVLATSGPGATNLVTGIATAYMDSVPMVAFTGNVP
                     TSSIGKDGFQEAYIEGITVPITKHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPK
                     DVTAAVCEFTPKQPEPIRTVTTYNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLR
                     DLLHKAEIPATYTLMAAGVVPYGDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDR
                     VALNPKTFAKNATIIQIDIDASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPEWMK
                     MIQSWQAQDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSR
                     GFITSGGLGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIIT
                     VIFNNSVLGMVRQWQTSFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFA
                     DALQQKGPTWIECIIDKDEKVLPMIPGGGDINDIIME"
     CDS             8166..8729
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_8"
                     /sec_met_domain="ALS_ss_C (E-value: 1.4e-28, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             8829..9848
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_9"
                     /sec_met_domain="IlvN (E-value: 5.6e-75, bitscore: 240.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.2e-66, bitscore: 210.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             10015..11673
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_10"
                     /sec_met_domain="ILVD_EDD (E-value: 6.1e-224, bitscore:
                     733.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGSYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLAKHAGMAVMEMVRKGITARQIINERSIRNALTCDMALGCSTNTVLHLLAIAYEA
                     GVPIDLKLFNEISAKTPNLCHLAPAGPTHMPDLYAAGGIPAVQAELAKKGLLDLEVPTV
                     TGKTLGENIKGAHILNEKAIRPIENPYSETGGLQILWGNIAPDGCVVKRSAVAPEMQQH
                     SGPARVFNSEEEAIAAIYAGKIVPGDVVVIRYEGPKGGPGMREMLNPTSALAGMKLDKT
                     VALITDGRFSGASRGAAIGHVSPEAASGGPIGLIEEGDTISIDIPNASITLEVSDAVLA
                     ERKAKYVAPEPNIKTGWLSRYARMVTSANLGAVLK"
     CDS             complement(11720..12391)
                     /locus_tag="ctg71_11"
                     /transl_table=11
                     /translation="MESTISAAPQISIDREKTLRSHRRYWVLRRAQDIVFSLLALILLA
                     PLALLISLAIVLDSPGDGAIFRQRRVGRDGKLFWLYKFRTMCPDAEEQLNELLSQNQMD
                     GPVFKIKGDPRITRVGRFLRKTSLDELPQLLNVLQGDMSIVGPRPALPREVELYSDYQR
                     QRLYVTPGLSCYWQIAPHRNEMSFDEWVALDLKYIQERSFWVDWKIIFLTVRAMLMKYG
                     E"
ORIGIN
        1 ccctgacgct ggaccccacc cccgctgctg tgccgcagga ggaaaagccc gccgctgccc
       61 ctgccccgga ggcacaggtg aacctgaccc ccgaggagca ggccatggtg gatcagtttg
      121 cccagaagat cgatatcacc aacagccagc aggtgctgca gtacggctct gcctgccaga
      181 agaagatcgg cgatttctcc gaagcagccc tctccaaggt gtccaccaag gatctgggcg
      241 aggtgggcga tatgatcacc gacctcattg gcgagctgaa gagctttgac gccaacgagg
      301 agcagcagaa gggcattatg ggcttcttca agaagaaaac cagccagctg gatgccctca
      361 agaccaagta cgacaagacc gagaccaacg tggaaaagat ccagtccatg ctggaagccc
      421 atcaggtgca gctgctcaag gacatcgcca tgctggacaa gatgtacgag ctgaacatgg
      481 catacttcaa ggaactgagt atgtatatcc ttgccggcaa gaaaaagctg gccgatgtgc
      541 gtgccaacga attgcagcag gccatggata aggccaaggt ctccggtctg ccggaggacg
      601 cacaggccgc ccgcgacctt gccgaccagt gcgagcgctt tgagaaaaag ctgtacgatc
      661 tggaactgac ccgcaacatc agtttgcaga tgggcccaca gatccgtctg ctgcagaaca
      721 acaacaccat gatggcggaa aagatccagt ccaccatcgt aaacaccatc ccgctgtgga
      781 agaaccagat ggtgctggca ctgggtctgg cacacagcca gcaggccatg caggcagagc
      841 gcgccgtgac caacatgacc aacgacctgc tgaagaagaa cgccgaggcg ctgaagctgg
      901 gcaccatcga gaccgccaag gagagccagc gcggcatcgt ggatatcgag acgctgcagc
      961 agaccaacaa gagcctgatc gagacgctgg acgagctgaa caagatccag agcgagggcc
     1021 gcgcaaagcg tgccgccgcc gagcaggagc tgacccgcat cgaggacgaa ctgaaaacca
     1081 aaatgatgga gatccggagc tgaaatggca aacgctgatt tttctcagaa caaacaaacc
     1141 gctcccggcg gttttgacgc gggcagctac cgcgaaaaag caaagccgga gcagactgta
     1201 aggctgacgc cccgccagca gaagctggcc gcactggaag caaagctgcc cgcagcgctt
     1261 tccacccggg cggcggcgct ggctttaagc gtggtggtga tgctggtcgc ctttttcggc
     1321 tttggcagcg ccaagctgcg gggcaagtac aacaccgccc gccagtggtt taccgcaggg
     1381 gtcgccgccg acaacggtta taacctgagc gaggagctga ccacccggga gaatacggcg
     1441 gcgaatattc tgaccactgc ctccaacacc cttggcgcag acagcgccga ggtgctggct
     1501 gcacagacgg cgctgaacga tttctccgct tgtctgcagg cggtgcagaa cggcggtaaa
     1561 agccagtcgc tgacctcgct gccctattat cagggcagca cgatgcacgc gctgtatcag
     1621 gccgatcagg cactgggcgc tgccatcgac cagctgtatg caaaattgca ggagcaggcc
     1681 gcagacccca tgaagatggg tgcggtgcag gggcagtacg gccaattcaa cagtgcggcc
     1741 accatcattg gtaccttgca gtacaatacg gcggtgtatg aatatcagaa ggatgtcggc
     1801 ggcttcccgg ccggtgtgct gggcgcagtt gccggcgtga aggaggttga gcccttcgca
     1861 tgaaaaactt tgcaaaacgc atcagcgcgc tggtgctggc cgtggtggtc agcgcggcgg
     1921 tgttgtgccc ggcggccttt gctgcccagc tgcccagcct gcccaaagat cagtgcgtgg
     1981 tggacgatgc cggtgtgctg agcagcagca ctgtgcagac catcaccgaa ctgaacgccc
     2041 agctggaatc cagctgcagc ggcgcacaga tcggtgtact gacagtagaa tacacgggta
     2101 atgattccac agaggattac gctgtgcagg cggccaatgc ctggggcatt ggttcttcta
     2161 ccggcaaaaa tggtgtgctg atcctgttgg taatggagac ccagcagtac gccgacggcg
     2221 attactatat tgccacaggt gacggcttcc gcaacactac cttggaaaag caggccagcg
     2281 ccattgccca gaccatggaa gatcagtttg ccgcaaagga ttatgacggt gcagtgacca
     2341 cctgtgcccg gaatgtggca aacaccatcg cagatattta cggggtcagc ctttccggca
     2401 gcgccggcaa cggcagcacc gtgcagcccg ggcatcaggg cagccagagc agcggcggca
     2461 gcgccctgac cgacatcctg acccttgtgg tcagcgttgt gctgctcatc gtcatcatcc
     2521 ggtcggtggc ctatgttttt gccagcccct gcggctggct gtggtgcttc ggcgggcccc
     2581 ggcctccgcg cggcggcggc tttggcggca tgggcggcgg ctccttcggg ggcggtgccg
     2641 ggcgcggtgg tttcggcggc ggcagctttg gcggcggcgg ctccttcggg ggcataggcg
     2701 gcggcagctt ccacggcggc ggcggtggcc gtgggcggta atgagaataa aaagagaaag
     2761 gcggtggcgc tttaccactg cctttctctt ttttatgcca tttatcgtga atgaaattca
     2821 tttgacaaaa caatttttgt aacttatact ggatgacatc acgaaaaata aaggaagtat
     2881 ctgtcatgct gactctggat aagatctacc acgccgcctt tgtactgaag gacgtagcgc
     2941 gcaagaccga cctcatcgaa gcccccaagc tgtccaagga ctgccagctg tacctcaaga
     3001 ccgagaacct gcaggccacc ggcagcttta aggtgcgggg cgcttactat aaaatcagcc
     3061 agctttccga ggaggagagc gccaagggcg tgattgcctg ctctgcgggc aaccatgcgc
     3121 agggcgtggc gctggccgct acccggcgcg gcatccgcag catcgtctgt atgccggacg
     3181 gcgcacccct gatgaaggtg gaaaacacca aaaatctggg cgcggaggtc tgccttgtgc
     3241 ccggcaccta cgacgaagcc cacgacaagg ccgtgcagct gcaaaaggag tacgacatga
     3301 cctttatcca cccctacgat gacgagcagg tcatcgccgg gcagggtacc atcggcttgg
     3361 agatccttga ccagctgccg gatgtggatg ctgtggtggt gccggtgggc ggcggcggac
     3421 tgatctccgg tattgccttt gccatcaaga ccctgcgccc ggaggtcaag gtgtacggcg
     3481 tacaggccga gggtgccccc agtatgtacc gcagcctgca cgagcacaag taccagaccc
     3541 tgaaatctgc ttccaccttt gcggacggta ttcaggtcaa gaccccgggc gagctgacct
     3601 atcagctatg cgagcagtat gtggacgata tcgttaccgt gaccgaggac gagacggcgg
     3661 cggccattct ctccctgatg gagaaccaga agctggtggc tgagggtgca ggcgctgtgc
     3721 cggtggcagc agtactgttc cacaagctgc cggtggaggg caaaaaggtg gcctgcgtca
     3781 tctccggcgg caacattgat gtgaacatcc tgaaccgtgt catcacccgc ggtcttgtca
     3841 tgagcggccg caaggcaaac ctgaccatcg cgctggagga caagcccggc cagctgaaaa
     3901 aggtggccga ggtggtatcc cgctgcggca gcaatgtggt gtcggtgcag catgacggct
     3961 ccgaccccaa tatgcccatc tccagctgct tcctcaagct gacgctggag acccgcgatg
     4021 ccgcccagat cgagcagatc cgcaccgagc tgactaaggc cggtttccag ctggtcagcg
     4081 agcgggtgta aacttcatcg tttgcaagag cgaaagcctt cccccggacg gaggaaggtg
     4141 gatgcgagcg tagtgagcag acggatgagg gcgcaggcaa gcagcagctt acgggaaatt
     4201 accccctcat ccggctctat ccgaagaaaa aagcgaattt gttctaaact tgatgtaata
     4261 taaaggagaa aatataccat gaaagtcgta tctaccgcca acgcacctgc cgccatcggc
     4321 ccttacagtc aggcactgga tctgggcaac atggtgtttg tgtccgggca gatcccggta
     4381 gaccccgcca ccggcaccat ggctgatacc gtggagcagc aggccgcaca gagccttgca
     4441 aacctgaaag caattctggc cgaggcgggg ctttccatga acaacgtggt caagacggtg
     4501 atctttctgg ccgacatcaa cgattttgcc gcagtgaatg cagagtacgc caaggccttt
     4561 gccgagccgt tccccgcccg cagctgcgtg caggtagcag ccatccccaa gggcgcaaag
     4621 ctggagatcg agtgcatcgc cgtgcgggac tgagcgaata aagacaagaa aaacgggaca
     4681 ccggagcatc tgcggatgct ttggtgtccc gtttttgata tcagcttcgg aaagcaggtc
     4741 tttacttctg cacaccggcc tcgcattgct cgatgaattg cttggccacc cgggggctgc
     4801 ggccgccggc acgcagggca aaggcctcgg ccttgagcag cagctgctcg gtgggcatct
     4861 ggatgttgtg ctgcttggca agctcctcca gaatggtctc gaaccgtgcc ttttccggcc
     4921 gctggaaggt gaccgtcagg ccgaaccggg cggaaaggct catcaactcc tgccgggtgt
     4981 cggcttcgtg gatgtcgtcg ccagtgcggt ccgagagggt ctccttgatg aggtggcggc
     5041 ggttggaggt ggcgtacacc gcaatgttct gggcgcgtcc gcccacgctg ccctccaaga
     5101 tggccttcag ggcggcaaag ttgtcgtcgt tggcggtaaa gctcaggtcg tcgatgaaca
     5161 ggatgaactt gagcgggttt gccgccagct tgtccatcag gtcggggatc tggtacagct
     5221 ggttcttttt cacctccacc agccgcagcc ccccggacgc aaactcgttg gcaatggcct
     5281 ttaccgcgct ggatttgccg gtaccggcgt caccgtacag cagcacattg ttggcgggca
     5341 tcccggccag cagcgccttt gtgttggcga tcaccttttc ccgctccttc tcgtagcctg
     5401 gcagttcgga aaggcgctgc gggtcggggt attttaccgg cacaagctga ccgttttcca
     5461 ccgtgaatac atagtgcttt gcaaacatgc cgtagccctt tttgcccacc tcgctcatgc
     5521 gctgggcgta ggcggcggca aggtcaagct cacaggtctg ccactggggc aggaacgcca
     5581 actccggccg ctgcgcctgc tccgagtagg cggtctggaa cagttcgtcc agcgtcagcc
     5641 cgcacagctg ctgcaaaaac tgcagctcgc tgtccaaggc gctttgcagc agcgcatcca
     5701 gctgcccggc agcggcctgc cgcacgcaga tggtctcggc ctccagcaca gcattgctca
     5761 ggtagctgcc ccagttggtg gtgtactcga acaaagcggc ctcaaaggcg gctacggcat
     5821 cgcacaccgg gccgtaggag gagcagcccg cctccatgcg gtcggtcagg tctaaaagct
     5881 ttgccacaac agggtcgttc agcagggcgc ggaacacaac aagcccatgc agatgggcat
     5941 tccattctct taatttcata ggtcgatccc ttttcctctc cattagcaca taccctacaa
     6001 aacgcaggta cgcggatatc aaaagtatac agcggttcgg gcggggatgc aaggggtgtt
     6061 aaaaatgctt catctttcgg ctgattcagg ttacaaattg tcgattgaca aaagcccggt
     6121 ttatagtata atttacatca acaaatgcgc agatgggaaa aagtaccaca cgatccccac
     6181 tgttcagaga gctgccgtct ggtgcaaggc agtcagcgtt tcgtgcggaa aatcatcccg
     6241 gagcagcctg cccaacgggt gcaaaaccct tgtaagcagc gccggttgca gccgttaccg
     6301 tgcagggctt tgttggaagc ccgtgagagg gtgtgcacag cacgccaacg agagtggtac
     6361 cgcagagagc ttgatgttac aaggtctttg tctcttgaag aaagcagggg acaagggctt
     6421 tttctttttc aaaagctctc cctgagggaa tggataagaa gtggaacagg aataggagca
     6481 acaccatgca gttgaatggt tctcagatct ttgtagaggt cctgtgcgag cagggagtgg
     6541 acactctttt tggctacccc ggcggcgctg tgctgaacct ttacgacgag ctgtataaga
     6601 atgccgaccg catcacccat gtgcttaccg cccacgagca gggcgcagcc catgccgcgg
     6661 acggctacgc ccgcgctacc ggccgcaccg gcgtggtgct ggctaccagc ggcccgggtg
     6721 ccaccaatct ggtcaccggc attgccaccg cctatatgga ctcggtgccc atggtggcct
     6781 ttaccggcaa cgtgcccacc agcagcatcg gcaaggacgg ctttcaggaa gcttacatcg
     6841 agggcattac ggtgcccatc acaaagcata acttcacggt gcgccgggta gaggacttgg
     6901 ctgacaccat gcgggcagct ttccgcattg cgcagagcgg ccgcaagggc ccggtgctgg
     6961 tggatatccc caaggacgtg actgcagcgg tgtgcgagtt cacccccaag cagccggagc
     7021 ccatccgcac cgtaactacc tataatgagg agcaggtgca ctgggcggca gacctcatca
     7081 acgccgcaca gcgtccgctg gtgtactttg gcggcggcgt gcgcagcgca gccagctgcc
     7141 agccgttgcg ggatctgctg cacaaggcgg agatccctgc tacctacacc ctgatggccg
     7201 caggcgttgt gccctacggc gacccgatga atctgggcat gctggggatg cacggctgct
     7261 acacctccaa ccgggcggtg gcagagtgcg atgtgctcat cgcggtgggt acccgctttt
     7321 ccgaccgtgt ggcgctgaac cccaagacct ttgccaaaaa cgccaccatc atccagatcg
     7381 acattgacgc cagcgagctg ggcaagaacg tggacgtgga tctttccatc gtgggcgatg
     7441 cagcctatgt actgaacgcc atgctgcccc agatcaagcc cgccaagcac ccggaatgga
     7501 tgaagatgat ccagagctgg caggcacagg attaccaccc cgtgtctgac cccacccggc
     7561 tgatgcccca tcaggtcatc ggcgaggtgt gcaaccagtg cggccccgat gccgtgtatg
     7621 ttaccgacgt gggtcagcac cagatgtggg cggcgcagta cctgcgccac accaagagcc
     7681 gcggctttat caccagcggc ggcctgggca ccatgggctt tggctatggc gctgccattg
     7741 gtgcccagat ggcactggga cgccagcagc gtgtggtgat gtttaccggt gacgcctcct
     7801 tccacatgaa cctgaacgaa gcctgcaccg ccgtcagcta cgagctgccc atcatcacgg
     7861 tcatcttcaa caactcggtg ctgggcatgg tgcgccagtg gcagaccagc ttttacggca
     7921 agcgttacag ccagaccgac ccccaccgca agaccgattt tgtcaagctg gcagacggct
     7981 ttggcctgaa gggctaccgc tgcaccaacc tgccggagtt tcaggaagcc tttgcagatg
     8041 ccctgcagca gaaaggcccc acctggatcg agtgcatcat cgacaaggac gaaaaggtgc
     8101 tgcccatgat ccccggcggc ggcgatatca acgacatcat catggaataa ggaggacaca
     8161 gcatcatgga atctgatcag cgtagggtca tcagcctgct ggtggacaac cagagcggcg
     8221 ttctggcccg ggtgtccagc ctgttctgcc gccgcggctt caatatcgac agccttacgg
     8281 tgtccgccac caacgacccg gcagttagcc gcatcacagt gaccattacc agcgatgaaa
     8341 aggccttgca gcagctggta ttgcagaccg agcggctgga agtcacccgg caggtgttcg
     8401 tgctggacag cgaaaaagcg ctggagcggg agctgctgct gctcaaggtg gaatcggacg
     8461 tgcacaaccg cacagagctg cgggagatcg cctgcatcta caaggcaaag atcattgatc
     8521 tttccccgga cagcatggtg tttgaactca tcggccggcc ggacaagctg gacgctttcc
     8581 tgaaaatgtt cgagggctac aacatccttg agcagtgccg caccggcgtt accgcactgg
     8641 agcgcggcgg gatgcaccag catatccaga agccgccgca ggaggtgcgc tccgtccagc
     8701 tgcccccgcc gggcgcaaga cgggcataaa tcacattgct tttccgctca gggtgagcga
     8761 aagatagaac agagcataca agaccggaag ataaaccaat cagaaaaagt aaaaggagac
     8821 taacgattat ggctatcaag aaatactacg attccgactg caacctcggc gtgctggacg
     8881 gcaagaccgt cgctgtcatc ggtttcggca gccagggtca tgcacactct gagaatctgg
     8941 ccgagagcgg cgtcaacgtt gtggtcggcc tgcgcaaggg ctctgcccac tgggcaaagg
     9001 cttctgagtt cgctgccacc catgacaact tcaaggtcat ggaggtggaa gaggctgcca
     9061 aggccggcga tgttgtcatg atgctggtgc ccgatgagct gtgcgccgat atctacaaca
     9121 cccaggttgc tccctacatg accgagggca aggcactggc ctttgcacac ggcttcaaca
     9181 tccacttcaa gaccatcacc gctcccaaga acgtggacgt catcatgatc gctcccaagg
     9241 gccccggcca catcgtgcgc cgcctgtaca ccgagggcga gggctgcccc tctctgatct
     9301 gcgtggagca ggactacacc ggtaaggcca aggatatcgc actggcttat gcttccggca
     9361 tcggcgcagg ccgtgcaggc atcctgcaga ccaccttcaa ggaggagacc gagaccgatc
     9421 tgttcggcga gcaggccgtg ctgtgcggcg gtgtttccga gctgatccac gccggtttcg
     9481 atacgctggt ggaggccggc tacgagcccg agatggccta ctttgagacc tgccacgaga
     9541 tgaagctgat cgttgacctg atcaacgagg gcggcttctc caagatgcgc tactccatct
     9601 ccaacactgc cgagtacggc gactaccgca ccggcaagcg cctgatcacc gaggagaccc
     9661 gcaaggagat gaagaaggtc ctgaccgaga tccaggacgg cacctttgcc tccgagttcc
     9721 tgaccgagat gagccccaag ggcggccgca aggtgcactt ccttgccaag cgccgtatgg
     9781 aggccgagct gcccatcgag aaggtgggtg ctgagctgcg cagcatgatg agctggctga
     9841 agaagtaaga ggagaaccct ctcagaccgc ttttcggcgg tcagctcccc cgaaaggggg
     9901 agtttttgtt gaaaagggaa ccttatagct cctccgcgaa aacctctccc tctcgggaga
     9961 ggtggcacga tacagccgtg acggagaggg ctttatcaga aaagaggatt tgcaatgaga
    10021 agtgacaatg tgaccaaggg ctcggagcgc gcaccgaacc gcagcctgtt ttatgcgctg
    10081 ggctacaccc cggaggaact ggagcgcccc ctcatcggcg tggtgagcgc ctacagcgag
    10141 atcgtgcctg gacacatgaa tctggataag atcgccgagg ctgtcaaggc cggtgtgcag
    10201 atggccggtg gtacccccat cctgatcccc gccatcggtg tatgcgatgg catcgccatg
    10261 ggtcatgtgg gcatgaagta ctctctggcc tcccgcgagc tgatctgcga cagcgtggag
    10321 accatgctga tggcacacca gctggacggc cttgtgctgg tgcccaactg cgataagatt
    10381 gtgcccggca tggtgatggc agcggtgcgc atggacgtgc ccgccgtggt ctgctccggc
    10441 ggccccatgc tggccggcag ctacggcggc gaggaagtga gcctttccaa gatgttcgag
    10501 gccgtgggcg cctataaggc cggtatgatc accgacgagc agctggagga ctgcacctgc
    10561 aactgctgtc ccagctgcgg cagctgctcc ggtatgtaca ctgccaacag catgaactgc
    10621 ctgtgcgagg ccatcggcat tgcactgccc ggcaacggca ccatcccggc tgtgtactcc
    10681 aagcgcctgc agctggcaaa gcacgccggt atggcagtga tggagatggt gcgcaagggc
    10741 atcaccgcgc gccagatcat caacgagcgc tccatccgca acgcactgac ctgtgatatg
    10801 gcgctgggct gctccaccaa cacggtgctg cacctgctgg ctatcgccta cgaggccggt
    10861 gtgcccatcg acctgaagct gttcaacgag atcagcgcca agacccccaa cctgtgccat
    10921 ctggcaccgg caggtcccac ccatatgccg gatctgtacg cagcgggcgg catcccggca
    10981 gtacaggcgg agctggccaa gaagggcctg ctggatctgg aagtgcccac cgtcaccggc
    11041 aagacccttg gcgagaacat caagggtgcc catatcctga acgaaaaggc cattcgtccc
    11101 atcgagaacc cctactctga gaccggcggt ctgcagatcc tgtggggcaa cattgccccg
    11161 gacggctgtg tggtcaagcg cagcgccgtg gccccggaga tgcagcagca ttccggccca
    11221 gcgcgggtgt tcaacagcga ggaggaggcc atcgccgcca tctacgcggg caagatcgtc
    11281 ccgggcgatg tggtagtcat ccgctacgaa ggccccaagg gcggcccggg catgcgggag
    11341 atgctcaacc ccacctctgc gctggcaggc atgaagctgg ataagacagt ggccctcatc
    11401 accgacggcc gcttctccgg cgcatcccgc ggtgctgcca tcggccatgt cagcccggag
    11461 gcggcctccg gcggccccat cggcctgatc gaagaagggg ataccatttc cattgatatc
    11521 cccaacgcct ccatcacgct ggaggtcagc gatgcagtgc tggccgagcg caaggcaaag
    11581 tacgttgcgc ccgagcccaa catcaagacc ggctggctga gccgttacgc ccgcatggtc
    11641 accagtgcaa atctgggtgc ggtgctgaaa taaacgtaac gaaagcgcct gttgtgcgga
    11701 tgcacaacag gcgcttttgt cactctccat atttcatgag catggcgcgg acggtgagga
    11761 agatgatctt ccagtccacc cagaagctgc gctcctggat gtatttcaaa tccagcgcca
    11821 cccactcgtc aaagctcatc tcgttacggt ggggtgcaat ctgccagtag cagctcagtc
    11881 cgggggtgac gtacagccgc tggcgctggt agtcgctgta cagctctacc tcccggggca
    11941 gtgcggggcg cggccccacg atgctcatat cgccctgcag cacgttgagc agctgtggca
    12001 gctcgtccag actggtcttg cgcagaaaac gtcccacccg ggtaatgcgg gggtcgccct
    12061 tgatcttgaa caccgggccg tccatctggt tctggctcag cagctcattc agctgctcct
    12121 cggcgtccgg gcacatggtg cgaaacttat atagccagaa cagcttgccg tcccgtccta
    12181 cccgccgctg ccggaaaata gctccgtctc cggggctgtc cagcacgatg gcaaggctga
    12241 tcagcagtgc cagcggcgca agcaggatca gcgccagcag ggagaacacg atgtcctgtg
    12301 cacgccgcag cacccagtaa cgccggtggc tgcgcagcgt cttttcccgg tcgatagaaa
    12361 tttgcggggc ggcgctgatt gttgactcca tgcaatgacc cactcctgcc tgtaaaatgt
    12421 gtagaatctt tacattattt taacataaaa caggacgcaa ttcaaccgga tgaagcgcgg
    12481 cgggcagggg actgtgagcc tgctgaaaaa aagtgaaaaa aggtggttga caaaaccctt
    12541 ttctcatgct aaaataaaca agtcgtccgg cgcacggatg cacaacaact gaatatgggc
    12601 gtgttcccga gtggccaatg gggacagact gtaaatctgc tgctttcagc ttcggtggtt
    12661 cgaatccacc cgcgcccacc aaacaagaaa aatccgaacc tatttccgat tggagaaggg
    12721 ttcggatttt tcgttttctt cgggtacaac aatgaaggct cccgtggacg gcgcaaacct
    12781 ccgatgcctt gtcgtagac
//
