LOCUS       c00097_gnlPro..        13423 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BHAHOFNO_97.
ACCESSION   c00097_gnlPro..
VERSION     c00097_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:45:53
            Original ID  :: gnl|Prokka|BHAHOFNO_97
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 36324
            Orig. end    :: 49747
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13423
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[46324:48795]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12471
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13423
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13423
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(488..1072)
                     /locus_tag="ctg97_49"
                     /transl_table=11
                     /translation="MTDKKLMELLVVIDDHYGRIRSKEERMADTKIYIQAFGAIPDEIV
                     EKALYTAFTQCRYQNQLIVDWCAEVKKLLTAGLPSANDLWAQAATAARQITANLYYMTH
                     GGLVTPAGKLTGEDFKARNAEIFATLPVAVQRWAGSPADLSMTFGRDGADLLQFVKPGF
                     VRAVSEAPIESLQPPALPGGAALAQIGGGTA"
     CDS             complement(1069..1527)
                     /locus_tag="ctg97_50"
                     /transl_table=11
                     /translation="MQTGDSTADNSVDNVHTDIRDKRTDIRDKEIRDKDKDNGSPAVDA
                     GLAEIIRSFEDNLGGFPPAAREDLLGWREIFTDDLILLAIKKAALAGVRKWSYVNGILK
                     VWKNEGVRTLGDVQSRDERRKPPAGQQPKRSAAEDYNEIFGELLGGST"
     CDS             complement(1936..2481)
                     /locus_tag="ctg97_51"
                     /transl_table=11
                     /translation="MLNNCIFQGRFAADPEMRTTQSGLTVASFRMAVDRDNVGQDGRRA
                     TDWLNFVAWRKTAEFVCQYFRKGSTALVECQCQTRSYEDRNGQKRTATEFVVQKIHFCG
                     PKTEQRVDDGGEAPPPGYQQSCQQPSYQNQQPQQMGFATQNQRQQWQQSAPGGQQPSYS
                     QGDPDDFSVIDDSDDLPF"
     CDS             complement(2471..2662)
                     /locus_tag="ctg97_52"
                     /transl_table=11
                     /translation="MEDLNVQTIAIPVEEYKDLLRAQTELAIIYQKNANGDAYGTGTFV
                     QEMRNAFCNVRQEDAHAE"
     CDS             complement(2650..3039)
                     /locus_tag="ctg97_53"
                     /transl_table=11
                     /translation="MKGRIVICNYCGTPADFVDSSVVYHGHSFGMIYLCPRCGAYVGVH
                     KGSDKPLGRLANSELRNWKKAAHAAFDPLWKYGPYRGRRNEAYRWLSEKMGTPIEFTHI
                     GMFDVDQCRKVVRIMREERNRLWKI"
     CDS             complement(3036..3566)
                     /locus_tag="ctg97_54"
                     /transl_table=11
                     /translation="MTGRLVDISFSLNRKQRITLEVDSDFRNLWDKLNQEPLLDIEIKK
                     HRNKRSRSANAYFHVLVNKIAAETGESDDLVKERLVVAYGTVARDKDGCTVGFKLPVSV
                     DVHDLYKYTRCFDVREEDGKWFNCYLVYKDTSKMDTKEFSHLIDGAIEEAKALGIETDT
                     PEQLARYKEEWSQ"
     CDS             complement(3563..4174)
                     /locus_tag="ctg97_55"
                     /transl_table=11
                     /translation="MAAYLITHSLLSSWLHLIRENPYEDLTTEGDPLAEFMLVLRREPT
                     PRTEAMQNGIDFENLVTSIVNGHDDPNNPWSWAAGQIAAIIKGGQLQFKSRKTIQVRGM
                     DVVLYGRLDALKAGTIYDIKFSRGYERGKFYSSTQHPTYMLLIPEAQQFSYLVSNGMDV
                     WTECYRRDETPDIRPIISDFFDWLDAYGLMAEFKEHWKAL"
     CDS             complement(4175..5125)
                     /locus_tag="ctg97_56"
                     /transl_table=11
                     /translation="MIRNPNDIQDGAKKIRMLIAGYPGIGKSTLALSSPRPLHIDCDFG
                     IDRIEPRYRMPYIQPRSYDEILNDLKPENLKDFETLVFDTAGKLITLMGLWAIKQNPKY
                     GQRDGSLSLKGYGFVGREFVRLMDYCFYELKKNIVVVFHATEEKDGDNTRLRIKVEGQT
                     KNNVWEPMDLGGFVEMYGNDRTIGFSNCERYFAKGTRGIHGVYKIPALGPGSQNDFLTK
                     LFEEYNSKAAEEVAANAKENEAYEQVMQEGSKIIAGIKDADTVNAAMQPFKNLQHHLTS
                     SRELNAMWKAKIAALGLVFDSTEVKYVPKSTEEAQ"
     CDS             complement(5154..5309)
                     /locus_tag="ctg97_57"
                     /transl_table=11
                     /translation="LKVRGKKLTRKQKEALSAQGWDFRLYLCVRDGPDFMELVNRTTGK
                     YVMFRK"
     CDS             complement(5306..5593)
                     /locus_tag="ctg97_58"
                     /transl_table=11
                     /translation="MDLEKFYFTYGSDDVQPYCGGWTEVWAPNYQMACQAFRVVHPDLI
                     PNVLNCASSYTAKEFEKTKMFGPGGNFGLRCRETITLNIAVNKAEEGVIF"
     CDS             complement(5593..5967)
                     /locus_tag="ctg97_59"
                     /transl_table=11
                     /translation="MKGLVFDTENRMQFKDFGEPLLDNLQKEVGGCIEVVHPKYLPEGL
                     CMVIDDEGLLKGYAINSIASVLYGTPEHGQPIVGTAVILREGFVAGELDFMSLDDGDEV
                     GLMLLFSALGICIKNESEAE"
     CDS             complement(5972..6148)
                     /locus_tag="ctg97_60"
                     /transl_table=11
                     /translation="MLYPADEEAGYPEPPVCPLCHQRCDTIYRTDDGVIVGCDRCLEAA
                     DAWEVRECFPEKE"
     CDS             complement(6132..6326)
                     /locus_tag="ctg97_61"
                     /transl_table=11
                     /translation="MTRILMIVYGITAEQAAARALAAQFAVTSVIAALFVWLDSMGMFD
                     DVGRWMGRKLREVLDAVSG"
     CDS             complement(6323..6499)
                     /locus_tag="ctg97_62"
                     /transl_table=11
                     /translation="MDTTIHINVADIPPEVGESFGRVTLAGFKKFIAQPGNREKLEAQM
                     AARKARKERECKE"
     CDS             complement(6539..6787)
                     /locus_tag="ctg97_63"
                     /transl_table=11
                     /translation="MKHLQPKRKRGDTTVTNTNLLRIKIDQSGYKMKYVATRIGLTYQG
                     FLNKLRNKSEFTASEIKGLCVLLDIDVNEKESIFFCG"
     CDS             6916..7470
                     /locus_tag="ctg97_64"
                     /transl_table=11
                     /translation="MTIGQRIKVRREELNMSQEELAKRIGYKSRSSINKIELDLYSLQQ
                     SKIKAIADALDTTPSYIMGWDEEASRNEWASKFRDSVMQILNNADPADLEAAGISVQEI
                     EEELSGSDSISLVTACAIADELGESLDSLLGHTPKEMIKAALQQEDGQTAEIIELLLDL
                     PADRQQEALNYLRYLSERAEK"
     CDS             7974..8180
                     /locus_tag="ctg97_65"
                     /transl_table=11
                     /translation="MWNGKSISYSLALEDNTTIYKDPESKIEIPNIKVVSVVDEIRGLK
                     QLLDEGILTEEEFAAKKKQLLGI"
     CDS             8200..9804
                     /locus_tag="ctg97_66"
                     /transl_table=11
                     /translation="MARKKNIAAGQDAVIYARYSSHNQREVSIEQQVSECMKHAAELGL
                     HVVGTYEDRAISGKTDNRPRFQQMMRDAEKGKFQAVVSWKSNRIGRNMLQAMVNEAKLD
                     DYGVKVFYAEEDFDDTAAGRFALRNMMNVNQFYSENMAEDITRGLYDNASKCMANGRQP
                     LGYKRGEDGRVVLDEANAAVVREIFTRVAAGDLFVDIARDLNAQGIKTSKGANWNKGSF
                     QSICQNERYRGIYIYGDVRVADGIPRIVSDDLWYRVQEAMRMKKNPVGTRHRVGAEDYL
                     LTGKLRCGHCGSYMTGVSGTSRNGELHYYYTCQKRRTEHACDKKNIRRDVIEPAVAQAI
                     KMYCLTDDVIAWIADRTVEYWEKHDNDLQIEALEQQLEENKKATSNMLKAIEMGIITEA
                     TRTRMVELETEQSRLSVQLNVAKEDVVKIDREQIISYLELLQQGDIYDRDFQMELFKNF
                     LVAVYVYDDNRMKLVFSCMGDQNSVEIPLVTGEDPPDGGLSPDAKMFVLTPDSSTRTKA
                     LHKNVWCFFVAAKRVRV"
     CDS             complement(10001..11212)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_67"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.4e-13,
                     bitscore: 43.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEEQLHRLPTPCYLLDEAQLRRNGEILLG
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RADEFEELLQYADHIVFNSPSQLAKFGPAAKAAGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWDAAVAAHPELPALLDGLHFHTLCEQDADALAVTLAAVEKKFADLLPRM
                     KWLNFGGGHHITRPGYDLATLESCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     HNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGKKACTVRLGGPTCLAGDIVGDY
                     SFDAPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGNCRELVHFGYQDFKMR
                     LGAQ"
     CDS             complement(11212..12471)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg97_68"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2e-44, bitscore:
                     144.7, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 8.5e-33,
                     bitscore: 105.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTATKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWNTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHDPALVD"
     CDS             complement(12511..13386)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg97_69"
                     /sec_met_domain="Arginase (E-value: 6.1e-77, bitscore:
                     250.9, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPNVETFIGCDSSYRAASIVLYGAPYDSTTSYRPGARFGPAAIR
                     HESYGLETYSPYQNADLTDFDVFDSGDLELCFGSSELALADIEARAEEILKDGKFPLLL
                     GGEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACVLRRCHELVGDGHI
                     HQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYLTIDLDCLDPSCFP
                     GTGTPEAGGVSFLQLLDAIRTVTKANIIGADLNELAPTLDTTGVSTATACKVLRETLIA
                     LDKGWPGFQV"
ORIGIN
        1 gcatgggtgt ttaccgccac gtccagcttg ttacctacca cagcactccc ggtgtcctga
       61 acgacccgga gacctacacc ctcgatatag atcaccgtgc cgtagggcag gatgctggtg
      121 tcagctgcca cggtcacgcc cggctgcgcc tttgcgccgc tggatgtaat gccgtgtccc
      181 tcgccgcaga tgtgggcgta ttcctcggtg cagtaggcag tgcagctgaa tgacccggcg
      241 tatgtaagtg tcaaatcgat ctgcgctgcc agttctgcgg ttaagttgtc aacctcggtc
      301 tgaagctggc tggcgttttc ctctgcatcg atagcccgca tctgccagtt ctggaagcgg
      361 ctggcgtaga tgtcccgctc gatttccagc tcgtctactc gcctggagta ggccgtgctt
      421 gcgaggatgc agccaaccat cgcacacgaa acgcccacga tcaggctgtg aaaaggactt
      481 ttccgcctca tgccgtgcca cctccaatct gcgccagagc tgccccaccg ggcagggccg
      541 ggggctgcag gctctcgatc ggagcctcgg acaccgcccg gacgaagccc ggcttcacga
      601 actggagcag gtctgcgccg tcacggccaa aggtcatgct caaatctgcc ggagagccag
      661 cccagcgctg caccgccacc ggcagggtgg cgaagatctc agcattccgg gccttgaagt
      721 cctccccggt gagcttcccg gcgggggtca ccaacccgcc gtgggtcatg tagtacaggt
      781 ttgccgtaat ctgccgggcg gcggtcgcgg cctgtgccca gaggtcgttt gccgagggaa
      841 gcccggcggt cagcagcttc ttgacctcgg cgcaccagtc aacaataagc tgattctggt
      901 agcggcactg cgtaaatgca gtgtacaggg ccttttccac gatttcatcc gggatagcac
      961 cgaacgcctg gatatagatt ttggtatctg ccatgcgttc ctctttgctg cggatgcggc
     1021 cgtagtgatc atcaatgacc accagcaact ccatcagttt tttgtctgtc atgttgaacc
     1081 tcccaaaagt tcaccaaaaa tttcattgta gtcctcggca gcggagcgtt tgggctgctg
     1141 acccgccggg ggcttgcgcc gctcgtcacg ggactgcacg tcaccaaggg ttctcacacc
     1201 ctcgtttttc catactttca ggatgccgtt gacgtaggac catttgcgaa ccccggccag
     1261 agcggccttt ttgatggcca gcaagatgag gtcgtccgta aaaatctccc gccagcccag
     1321 caggtcttcc cgcgctgctg gtgggaaacc tccgagattg tcctcgaaag agcggatgat
     1381 ctcagccagc ccggcatcga cggccggact accgttatct ttatctttat ctcttatctc
     1441 tttatctctt atatctgttc tcttatctct tatatctgta tggacattgt ccacgctgtt
     1501 gtctgcggtg ctgtctccag tctgcatagg aagttgtctg cgacgatttt cacgttggag
     1561 acgtttctgt gcggagtagt cagtttcact gccgaccatt tcagcatgat tgacaagaac
     1621 cagcgttcca tcctgttctt cataaatcag accaagttgt ttatagagac caagagcaac
     1681 acggacggta tccagcgaaa accatttaca gtcacgctga attttctcaa tatcaaaagg
     1741 aataatgatg tcgccaattt gacaggtcag gcggccgccc gtattgatgg ttttgagaca
     1801 gagcatttga taaaggacga catagctggc accgttcggc tggctcatca ggaaatcgac
     1861 cacttctgaa ttcatgaacg aatccttgag ctttatccag tagtatcttt ttccagttgc
     1921 cattatcaga cccccttaga acggcaggtc gtcgctgtca tcgatgaccg agaaatcgtc
     1981 agggtcgccc tgcgagtagc tgggctgctg cccgccgggg gcactctgct gccattgctg
     2041 ccgctggttc tgggtggcga agcccatctg ctgcggctgc tggttctgat aggacggctg
     2101 ctggcaggac tgctggtagc ccggaggcgg tgcctcgccg ccatcatcaa cccgctgctc
     2161 cgtctttggg ccgcagaagt gaattttctg caccacgaac tcggtggcgg tgcgcttctg
     2221 gccgttcctg tcctcataag accgggtctg gcactggcac tccacaagag ccgtgctgcc
     2281 cttgcggaaa tactggcaaa cgaactctgc cgttttacgc catgccacga aattcagcca
     2341 atcggtagcc cgccggccat cctgaccgac attgtcccgg tcaacggcca tgcgaaagct
     2401 ggcgactgtc aggccgctct gtgtggtccg catttcagga tcggcagcga agcggccctg
     2461 aaatatgcaa ttattcagca tgcgcgtcct cctgcctgac gttgcaaaat gcgttccgca
     2521 tctcctgcac gaaagtgcca gtgccgtaag catcaccgtt ggcgttcttc tggtagatga
     2581 tggcgagctc ggtctgtgcc cgaagcaagt ccttgtactc ctcaaccggg atagcgatgg
     2641 tctggacgtt caaatcttcc ataaccggtt cctttcttct cgcatgatgc ggaccacctt
     2701 gcggcactgg tccacatcga acattccaat atgcgtaaat tcaatcgggg tgcccatctt
     2761 ctcggacagc cagcggtagg cctcattccg gcggccacgg tatggaccgt atttccagag
     2821 cgggtcaaat gctgcatgag ctgccttttt ccagttgcgc aactccgaat ttgccaagcg
     2881 gccaaggggt ttgtcagacc ccttgtgtac gccgacatag gcaccgcagc gagggcagag
     2941 gtaaatcatg ccgaagctgt ggccgtggta aaccaccgaa ctgtccacga agtctgcggg
     3001 cgttccgcag tagttgcaga tgacgattcg gcctttcatt gtgaccattc ctccttgtac
     3061 cgggccagct gttccggggt gtccgtctcg atacccagag ccttggcctc ctcaatcgca
     3121 ccgtcaatca ggtgcgaaaa ttctttcgtg tccatcttgc tggtgtcttt gtaaaccaag
     3181 tagcagttga accatttccc gtcctcttcc cgcacatcaa agcagcgggt gtatttgtag
     3241 aggtcgtgaa catctacgct gaccgggagt ttgaagccca cggtgcagcc gtccttgtcc
     3301 ctcgcaaccg tgccgtaggc cacgaccaac cgctccttca cgagatcgtc cgattcaccg
     3361 gtttcggcag caatcttgtt gaccagaacg tggaaatagg cgtttgcgct gcggctgcgc
     3421 ttattgcggt gcttcttgat ttcaatgtcc agcagcggct cctgattcag cttgtcccac
     3481 aggtttcgga aatcggaatc aacttccagc gtgatgcgct gcttgcggtt cagactgaaa
     3541 cttatgtcca cgagccgccc ggtcataagg ctttccagtg ctccttgaac tcggccatca
     3601 gcccataggc atccagccag tcaaagaaat ccgaaatgat ggggcgaata tccggcgttt
     3661 cgtcccggcg gtagcactcc gtccagacat ccatgccatt gctgacaagg taggaaaact
     3721 gctgcgcctc cgggatgagc agcatatagg tggggtgctg agtgctggaa tagaatttcc
     3781 cgcgctcata gcccctactg aacttgatgt cgtagatggt gccagccttg agggcatcga
     3841 ggcggccata caggactaca tccatgccgc gcacctgaat ggttttgcgg gatttaaact
     3901 gcaactgtcc acccttgatg atggcggcaa tctgcccggc ggcccagctc cacggattat
     3961 tggggtcatc gtggccgttg acaatggagg tcacaaggtt ctcaaagtca atgccgttct
     4021 gcatagcctc cgtccggggc gtaggctccc ggcgcaggac cagcatgaac tccgccagag
     4081 ggtcaccctc ggtggtcaaa tcctcgtagg gattctcccg gataaggtgc agccacgagg
     4141 acagcagcga gtgagtaatg aggtatgcag ccatttactg tgcctcctct gtggacttag
     4201 gaacatactt gacttcggtg gaatcgaata ccaaaccgag ggctgcgatt ttggctttcc
     4261 acatagcgtt cagttcccgg ctggaagtca ggtgatgctg caagttcttg aacggttgca
     4321 tagcggcgtt gacggtgtct gcatccttga tgccagcaat gattttgctg ccctcctgca
     4381 taacctgttc gtacgcctcg ttttccttgg cgtttgcagc tacttcttca gcggccttgc
     4441 tgttatattc ctcgaacagc ttggtcagga agtcattctg gctgccgggg ccaagggcgg
     4501 gaatcttata aacgccgtgg atgccgcggg tgcccttggc gaaataccgc tcacagttgg
     4561 agaagccgat ggtgcggtcg ttgccgtaca tctccacgaa accgcccaga tccataggct
     4621 cccacacatt gttcttggtc tgaccctcga ccttgatgcg gagacgggtg ttatcgccgt
     4681 ccttttcctc ggtggcgtgg aagaccacca cgatgttctt cttcagctcg tagaagcagt
     4741 agtccatcag ccggacgaac tcgcggccaa caaagccata gcccttgagg gacagactgc
     4801 cgtcccgctg accatacttg gggttctgct tgatagccca caggcccatc agggtgataa
     4861 gcttgccggc agtatcgaac accagcgtct cgaagtcctt gaggttctcc ggcttcaggt
     4921 cattcagaat ctcgtcatag ctgcggggct ggatgtacgg catacggtag cgaggctcga
     4981 tacggtcaat gccaaagtcg cagtcgatgt gcagcgggcg gggtgaggac agggccagcg
     5041 tggacttgcc gatgccgggg tagccagcaa tgagcatccg aatcttcttt gcgccgtcct
     5101 gaatgtcgtt gggattgcga atcataatgt ttactccttt tcagttaata ggtttacttg
     5161 cggaacatga cgtatttgcc ggtggtgcgg ttgaccaact ccatgaagtc cgggccatcc
     5221 cggacacaga ggtacaggcg gaagtcccag ccctgtgcgg aaagggcttc tttctgcttg
     5281 cgggtcagct ttttacctct cactttcaaa aaatcacccc ctcctcggcc ttattgacag
     5341 cgatgttcag cgtgatggtc tcccggcagc ggaggccgaa gttgccgccc gggccgaaca
     5401 tcttggtctt ctcaaactcc tttgcggtgt acgagctggc acagttcaag acattgggaa
     5461 tgaggtcggg atgaaccacc cggaatgcct ggcacgccat ctggtagttg ggtgcccaga
     5521 cctccgtcca cccgccgcag tacggctgga catcatcgga accgtaggtg aagtagaatt
     5581 tttccagatc catcactcgg cctcgctttc gttcttgatg cagataccga gcgcagagaa
     5641 caagagcatc aggccaactt catctccatc atcaaggctc ataaagtcga gttccccggc
     5701 cacaaagccc tcacggagaa tcacagcggt gcccacaatg ggctgaccat gttccggcgt
     5761 accgtagagg acgctggcga tgctgttgat ggcatagcct ttcagcaacc cctcatcgtc
     5821 aatcaccatg cacagtcctt ccggcagata cttgggatga accacctcga tgcagccgcc
     5881 gacctctttc tggaggttat ccagcagcgg ttcgccgaag tccttgaact gcatccgatt
     5941 ctcggtgtcg aataccaatc ctttcataaa atcactcctt ttccgggaag cactcacgga
     6001 cttcccatgc gtctgcggcc tccaaacagc ggtcgcagcc aacgattacg ccgtcatcgg
     6061 tgcggtagat ggtatcgcac ctctggtggc agagggggca cacaggaggc tcagggtagc
     6121 cagcttcttc gtcagccgga tacagcatcc agcacctccc ggagcttgcg ccccatccag
     6181 cggcctacat catcgaacat tcccatgctg tccagccaga caaacagggc tgcgataaca
     6241 gaggtcacag caaactgcgc cgccagggca cgagctgcgg cctgttcggc ggtgatgccg
     6301 tacacgatca tcagaatccg ggtcattcct tacactccct ttctttgcga gccttacggg
     6361 cggccatctg ggcctccagc ttctcgcggt tcccgggctg ggcgatgaat tttttgaatc
     6421 ccgccagcgt cacgcggcca aagctctcac cgacttccgg gggaatatcg gccacgttga
     6481 tgtgaattgt ggtgtccatg tggtcctcca tgtgttgcct gtagatgttt aatctacatc
     6541 agccgcaaaa aaatatgctc tccttctcat tgacatcaat gtccaggaga acgcagagac
     6601 ccttgatctc ggatgcggta aactcagact tattgcggag tttgttcaaa aaaccctgat
     6661 aagtcaggcc gattcgggtt gcaacatact tcatcttata gccggactgg tcaattttga
     6721 ttcggagcag atttgtgttg gtcacggtgg tatcacctcg ctttctcttc ggctgtagat
     6781 gtttcatcta ctgggcgtat attaccacat cgttgatgta ttgtcaacaa gtttttttga
     6841 aaaagcaaaa atatgttgac gatacaggta cgcgtgtact ataatagcat cagaagattt
     6901 tgggaggact atgatatgac tattggacag agaatcaagg ttcggagaga agaactcaat
     6961 atgtcccaag aggaactggc taagcgtatc ggttacaaat cgcgttcctc catcaacaaa
     7021 atagagcttg acctttattc gttgcagcag tccaaaatca aggctattgc tgatgcactt
     7081 gatacgaccc cgtcttacat catggggtgg gatgaagaag ccagccggaa tgagtgggcc
     7141 tctaaattcc gtgacagcgt gatgcagatt ttgaataatg cggatccggc cgacttagag
     7201 gctgctggca tcagcgttca ggaaatcgag gaagaactga gcggcagcga ttctatttcg
     7261 ttggtgacag cttgcgccat tgcggacgag ctgggcgaat cgctggactc tctgctgggt
     7321 cataccccca aagaaatgat aaaggccgcc ctccagcagg aggacggcca aacggctgaa
     7381 attattgagc tgcttcttga tttaccggcg gatcggcagc aggaggcgct gaattatctc
     7441 cgttaccttt cagagcgtgc agaaaaataa gtaaacgctc cttatcagca tccgacagtt
     7501 ttttgacttt ggcaaagatg tccgaccatt cgctcgtagt catacggcat ggctcctttc
     7561 tcaaatttac tgtcggcagc aactgaatta tatcaaatac gcacccgctt ttcatggaat
     7621 cgtggaatta taccgaaaat cggaaaaatt tgtgtgtttc tgacataata ttatgaaatt
     7681 tgcgttgcag aggtcatttt atggacttga aagaaattgc attgcggttg caggagttca
     7741 agagcgtttg tgtgaccgga agccctgcta tgctgagaag ccgaatggat tttctcgata
     7801 ttttatcagc atatagtttg accgcgagtg taagcgtatc aaaaaagaca gggcttttga
     7861 ttgtgtgcag tgacccaagg caaacgaaaa tcgaaaaggc aaatgctctg aatattccag
     7921 ttatttcgga gcagcaatgg tttgaacttg tgcccgaact tgaggccatt ggaatgtgga
     7981 acggaaagtc aatttcgtat tctctcgctt tggaagacaa taccaccatc tacaaagatc
     8041 ccgaatctaa aatagagata ccgaacataa aagttgtgtc cgtggtggat gaaatccgtg
     8101 gtttgaagca gctgctggat gagggaatcc tgacagaaga agaatttgct gcaaagaaaa
     8161 agcagcttct tgggatttga aaacggacgg tgatggttga tggctcgaaa aaagaatatc
     8221 gctgcgggtc aggatgccgt catctatgcc cgctactcct cccataacca gcgagaggtc
     8281 agcattgagc agcaggtcag cgagtgcatg aagcacgctg ccgagctggg gctgcacgtc
     8341 gttggaacct atgaggacag ggcaatcagc ggcaagacgg ataaccggcc tcgtttccag
     8401 cagatgatgc gggatgctga aaaagggaag tttcaggccg tcgtgtcgtg gaagtctaac
     8461 cgcatcggcc gcaatatgct tcaggcaatg gtcaacgagg cgaagctgga cgattacggc
     8521 gtaaaggtgt tttatgccga ggaagatttt gacgatactg ccgccgggcg ttttgcactg
     8581 cggaacatga tgaacgtcaa ccagttttac agcgagaaca tggcagagga catcacccgg
     8641 gggctgtatg ataacgccag caagtgcatg gcaaacggtc ggcagccctt gggctacaag
     8701 cggggtgagg atggccgtgt ggtgctggat gaagcgaatg cggccgttgt ccgggaaata
     8761 ttcacccgtg tggctgctgg tgacctgttc gtggacattg cgcgagatct caatgcccag
     8821 ggcatcaaga ccagcaaggg agccaactgg aacaaaggca gcttccagag tatttgccag
     8881 aacgagcggt accggggcat ctacatatac ggggatgtcc gggtggccga tggcattcca
     8941 cgcatagtga gcgatgattt gtggtacagg gtacaggagg ccatgaggat gaaaaagaat
     9001 ccagtcggaa cccggcaccg tgtcggggca gaagattatc tgctgaccgg gaagctgcgc
     9061 tgcgggcatt gtggcagcta catgacgggc gtatctggca ccagtagaaa cggcgagctg
     9121 cattactact acacctgcca gaagcggcgc accgagcacg cctgtgacaa gaagaacatc
     9181 cgccgggatg tcattgaacc ggctgtggct caggccatca agatgtactg cttgaccgat
     9241 gatgtcattg cgtggatagc agatcggacg gtcgaatact gggaaaagca cgacaatgac
     9301 ctccagattg aggcgttgga gcagcagttg gaggaaaata aaaaagccac ctcgaatatg
     9361 ctgaaagcca tcgagatggg gattatcaca gaggccaccc gcacccggat ggttgagctt
     9421 gagactgagc aatcccggct gagcgtccag ctgaatgtgg ccaaagagga tgtcgtgaaa
     9481 atcgaccggg agcaaatcat ctcctatctg gaactgctgc agcagggtga catctacgac
     9541 cgggattttc agatggagct gttcaaaaac ttcctcgtgg ccgtctatgt ctacgatgat
     9601 aaccgcatga agctggtgtt ctcctgcatg ggagaccaga acagcgtcga aattcctttg
     9661 gtgaccggag aagacccgcc cgatggcggg ctgtcaccgg atgctaaaat gttcgttttg
     9721 actcctgata gctccaccag aaccaaagca ctacacaaaa acgtgtggtg cttttttgtt
     9781 gctgccaaac gagtgagggt ttagctcacc caggagagtg ccgtgcatgg actgcaagag
     9841 agtcaccgtg atcagaatcg gcccggtaat ctccaccaga atgaaagcac tacacggaaa
     9901 cgtgtggtgc ttttttgttt tatctgccgt tcaccttacg tcccctttca tgaaaaaagc
     9961 gtttgtcgca gcccgcaggc cgtgacaaac gctttttatt ttactgtgcg cccaagcgca
    10021 ttttgaagtc ctgatagcca aagtgcacca gctcccggca attgccgtct gcgcccagca
    10081 gccagatagg cggcaggggc atcccgttga aggtgttgtt cttgcaggtg gtgtagatgg
    10141 ccatatcgcc aaagataagc ttatctccct cggcaagagg ggcgtcaaag ctgtaatccc
    10201 cgacgatatc ccccgcaagg catgtggggc cgcccagccg gacggtgcac gccttcttcc
    10261 ctgcctcacc ggcatccagc agcggcgggc ggtagggcat ctcgatgacg tccggggtgt
    10321 ggcaggctgc agacatatcc agaatggcaa ggctggtatc tccattgtgc agggtgtcca
    10381 gcacggtggt aaccagatag cccgcgttca gcgcccaagc ctcgccgggc tccagataca
    10441 cctgcacgcc gtacttctgc cgcaccgaca ggatgcagct ttccagcgta gcaaggtcgt
    10501 agcccggacg ggtgatgtgg tgccccccgc cgaagttgag ccatttcatt ctgggcagca
    10561 ggtctgcaaa ctttttctcc actgcggcca gcgtcaccgc caacgcatcc gcgtcctgct
    10621 cgcacagggt gtggaagtgc agaccgtcca gcagggcggg cagttccggg tgcgccgcca
    10681 cggcggcgtc ccactgggca cgggtggtgc ccagacggct gccgggggcg caggggtcgt
    10741 agatttcgtg gccttcctgc gtggagcact ccgggttgat gcgcagacca atgcttttgc
    10801 ccgctgcctt tgccgccggg ccgaactttg ccagctggct gggcgagttg aacacgatat
    10861 ggtcagcgta ttgcagcaat tcctcaaact cgtctgcccg gtaggcggcg cagaacacat
    10921 ggttctcctt ctccggcagc tcttccctgc ccaagcggct ctcgtacagg ccgctggcct
    10981 cggtacccgc cagatagggt gccagcaccg ggtagacatt gaagttggaa aaagccttct
    11041 gcgccagcag gatgcggcag ccagtgcgct gctgcacacc cagcagaatt tcgccgttgc
    11101 ggcgcagctg ggcttcgtcc agcagatagc agggggtggg caggcggtgc agctgctcct
    11161 cggacaggtt tgccagcccc gcaaagggcg ggcggctgtc gcgcacccgc atcagtccac
    11221 cagagccggg tcgtggctct cggagcgggg caggccgtac ttgtccagtg catccagata
    11281 cggatcggga tcaaactcct cgacggtgtg cacacccttg gtgttccact tgccggtgag
    11341 cagcatcagc gcgccgcaca tggcgggcac gccggtggtg tagctgatgg cctgagagcc
    11401 tacttccttg tagcactcct gatggtcaca gacgttgtag atgtagtagg tcttatcctt
    11461 gccgtccttt ttgccggtaa agatgcagcc gatgttggtc ttgcccttgg tgcgggggcc
    11521 aaggctggcg gggtccggca gcagcgcctt gaggaactgg atgggcacga tctcctgccc
    11581 gttgaagttg acaggggtgg tggacagcat tcccacgtcc tccagacagc gcatgtgatc
    11641 cagatagctc tggccaaagg tcatgaagaa gcggatgcgc tttgcctccg ggatgttctt
    11701 tgccagagac tcgatctcct cgtggtgcag caggtacata tccttgtcgc ccacctgatc
    11761 aaagttgtac tcccgcttga tgctcatagc cgggatctcc acccagtggc cgttctccca
    11821 gtagctgccg ggtgcggaca cctcgcgcag attgatctcg gggttaaagt tggtggcaaa
    11881 ggcatagccg tggtcgccgc cgttgcagtc tagaatatcg atggtgtcaa tggtatcgaa
    11941 ctcgtgcttt tttgcgtagg cacagtaagc ctgggtcaca cccgggtcga agccgctgcc
    12001 cagcagggcg gtcaggccgg cttcctcaaa ctttttggcg taagcccact gccagctgta
    12061 atcaaagtag gcagagaagc cggcctcctt gcagcgtttc tcgtagatgg cgcgccactc
    12121 cgggtcgtcg gtgttctcgg gctcgtagtt ggcggtgtcc atgtagttga cgccgcaggc
    12181 aaggcaggcg tccatgatgg tcagatcctg ataaggcagg gcgatgttca tcacgaggtc
    12241 aggctggtag gccttgatga gggcgatgac ctcttccacc ttgtctgcgt ccacctgtgc
    12301 ggtggtgatc ttggtggcgg tggtgggagc cagctcagca gccagtttat cgcactttgc
    12361 cttggtacgg ctggcgatgc agatctcggt gaacacctcg ggcacttggc agcacttatg
    12421 gatggcaacg gaggccacgc cgccgcagcc gatgatcaga actttgctca tgtcggttac
    12481 tcctttatct gtaaaatggt aggttcgtat ttatacctga aagcccggcc agcccttgtc
    12541 cagcgcgatc agggtctcgc gcagcacctt gcaggcggta gcggtggaaa cgccggtggt
    12601 gtccagcgtg ggggcaagct cgttcaggtc tgcgccgatg atgttggcct tggtcacagt
    12661 gcggatagca tccagcagct gcaaaaagct tacgccgcca gcctccgggg taccggtgcc
    12721 cgggaagcag gaggggtcaa ggcagtccag atcgatggtc aggtacaccg gcaccttgct
    12781 ctcgcacagc tgtgcggtca gttcggcaag gccggtaaaa tcaaacttgt gcatctcggt
    12841 gtgctgggca gcaaactcaa actctgcccg gtcgccgctg cggatgcaga actgatggat
    12901 gtggccgtcc cctaccagct cgtggcagcg gcgcagcaca caggcgtggc tgagcttcgc
    12961 gcccagatag tcgtcccgca ggtcggcgtg ggcgtcaaaa tgcacgatgt gcagatccgg
    13021 gtatttcttc accgcagcac gcaccgcacc cagcgtgacc aaatgctcgc cgcccagcag
    13081 cagcgggaac ttgccgtcct tcaaaatttc ctctgcccgg gcctcgatat cggccagtgc
    13141 cagctcgctg gagccgaagc acagctccag atcgccgctg tcgaacacgt caaaatcggt
    13201 caggtcggcg ttctggtagg ggctgtaagt ctccagacca tagctctcgt gccggatggc
    13261 cgccgggccg aaccgtgcac cggggcggta gctggtggtg gaatcgtaag gcgcaccgta
    13321 cagcacgatg ctggcggcgc ggtagctgct gtcgcagccg ataaaggtct caacgttggg
    13381 gtgcatcagt gttcctccac ttcccgcagc atctcctcca gaa
//
