LOCUS       c00056_gnlPro..        16768 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFOIBJPH_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:22:14
            Original ID  :: gnl|Prokka|CFOIBJPH_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 47197
            Orig. end    :: 63965
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16768
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[57197:60189]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12992
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16768
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16768
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(622..1830)
                     /locus_tag="ctg56_47"
                     /transl_table=11
                     /translation="METQQRSTEYNFQGIMYFFRREKIQCRYQFSLRDAVDITLLQRAL
                     TAALASAPYYTQRLVQEKREMWLEPNTEPCLVYPGSTMRNIPEQTNGYLFCVSCEGDTV
                     YFDWHHFLLDGHGVSPLLTSILEQYCNLRYGTAFAVPQIVCDPPYDMEAMLAEYPPVEY
                     GSDVIQRDVVQTYEGALRRTRVCLSKQSLVEKALANNAKPVSALMGLLCMAMREYLGKE
                     KIQYSYSSDTRDVAGVPNALYNCVCSFGHTVQLQTQTRLADFVSDVDADIRRDLQPESK
                     RHRMADQMGWVYKVNQQKAPLRIKQRVFQMGEYIGGTISDFWLSYLGNPLMPAAPELAQ
                     YTTDFGVWVPPDGASVGVEAASLNGKIILCIHNKAPNPGLAETLRKTFESEGVAVLEAE
                     DLD"
     CDS             complement(1837..2079)
                     /locus_tag="ctg56_48"
                     /transl_table=11
                     /translation="MERAEIISQITAILEDVAEVSPEDVTESSVLMDDLDLSSMEILTI
                     VADLEETFGLRIPEKELRNFVTMGDLVDYLAANVG"
     CDS             complement(2107..3576)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 211.8; E-value:
                     4.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_49"
                     /sec_met_domain="AMP-binding (E-value: 4.1e-65, bitscore:
                     211.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKVLDNVYDLVTLNMEQRFSERVALRFYDKETDEVTVVHYKDYA
                     RDIRRAVSYFQSTIPDIKGKKICLLNKNSYEYAVNTFGIILAGGVLVLLNQHKSWDELS
                     YELGLVDPAAILTDGDDYGTKEQLQADYGSILRPMDGFRAYEPVAEMPRCIGHDDLMIL
                     MFTSGTTGRSKGVMLSERNFFSVMRAHVQIGERMMEYKHDPELVVSQYTVLPMFHLGAF
                     ICLFSWAHGGWALNISGDIRNFYKEIRRMPSQVMAVVPVIMNSLHKDVMRGRKERLGEL
                     WVPICSSAMFDPQVMLDMATNGMFVVQTYGATETCGDGIINYAQDAKHIGAVGQGNDYL
                     DYKLEPDGELCIRGDSIMLGYYKDPEATAAVIDKDGWFHTGDLARVDEDGYYYITGRKK
                     NLIILDSGENVSPEELEGMLEKCPAVQECIVKELGKKIGVVVYCEKEHQQTVRDFIAQM
                     NRTVPLYKRIGVVEFSETPLPRNAAGKLVRK"
     CDS             3951..5066
                     /locus_tag="ctg56_50"
                     /transl_table=11
                     /translation="METTKPRTVNSIGMFDMLKGAGMLAIVLGHTAELYPLQLEGGLSL
                     TAFVGFIYRETLMAAFFIASGYGFRKRSISKCIHQQLKSLLKPFCYTAVFTTVLHFIIH
                     YKTFHYLPGSMTESIKVAGGFLLGLPHTATYFRQEFFSCGPMWYLLALLMGWILLDVIL
                     NIFPERYIPWAVGGAALLGWGASLVWELPFCLIQGAVITPYLYLGYLAKRQHWLDQPLS
                     RRMSCILWAAVLLIPAAALATRRTDCVSMAEWSLGPISILLDGLAGLLFIRLFLRWSQR
                     RNPLVRFFEAIGRRSLYIFCVHTVELIAIPWYLFAAKYADRPVLGISLQYILSLGSIWL
                     ICALLQRRRDLIIKLFPARRRTPQVHYAPRH"
     CDS             5133..5927
                     /locus_tag="ctg56_51"
                     /transl_table=11
                     /translation="MNHDAPMTPAAMQAHIAELEQQLKLSDEGVSQLAQRCLELEQQLL
                     ACQTELAKHSAEAENITLTLPQLFYDTGSGFSPRECLTATEDVYNELTHEVSVTFVLPE
                     DARAIRLDPGELACCITDLAISDERISFQSVNGLLLQEDSLLFLDVDPNLSLHCTTGFG
                     VGMKFAVNYHYYPLGRFLHEQPGKSLLRALNDLKLENAAAAQEAEEVLQASRAECMRLN
                     QQLLTLQGIQHEYQVSLETMRASSSWRLTAPLRRLLNLVRGH"
     CDS             5962..7569
                     /locus_tag="ctg56_52"
                     /transl_table=11
                     /translation="MYTSYSTLQRKQLSKQVYTDTQSTYLLVYAPGRHKALQAALQNQL
                     HRKFRLVTQLEDELTPDVAGVLLVSEDVECTPTALTYFAAALREGADLAVCDASFGFDG
                     STALYLSTRHLPGSSCALVSRALLDKVRAAARGKDSVTELLRLAHAMAQHSRCIPQALL
                     HFRRELCADDVFSAKGRRALILSHELTMTGAPIVLVSAVPVLRSLGFEVVVLGPSDEGS
                     LPLFLDAGAAVVTRPDCVTSSALWGLATSADFVLANTVVEAPVVNTLNGSFVPVLWWLH
                     DAFAGYPFISHSIPKALGKNVHLCAVGSHATAAMHSVRPDFEIEQLIYGLPDYAAEQFP
                     RYDISFAGGRPLFVTVGSLEHRKGPDIFCNAIRLLPSAVREKAAFLFVGKAADKGMYNA
                     VDSLVRDYPQTVFYRKRLERPEVKSLMEQCNCVVCASRDDPMPTFVTEGLIFGKPSIVS
                     EHTGTAGLVTEGVDGFLYKDDDPQQLADKLTWAIEHPEALAAMHGSCRRLYEQQFSNES
                     YVATLTRLVKELTDGEES"
     CDS             7747..8784
                     /locus_tag="ctg56_53"
                     /transl_table=11
                     /translation="MSQAAAQQPSRKKAVISLLVLLALTCIIVFTFKDHWAEITAALAQ
                     LSVWQVLAVLAVGLSYPLLEGCVAWVIVRSRLPQFTLRQGLDVGWCGTFGNVVTLGAGA
                     VPVQLYYLHKAGLPLGPGAGLMTLEYVFHKSTVLLYATVMLLLQRRWLAANTTGVMRYL
                     PMAYAVVAVIIVALVLLCVSPLVQNLARWLLGFLPKTEKWQQRRADWLEQLEVLSTESR
                     RLLADKPRCLKIFALQALKLFGLFCLPYLCIRFMGLSPLGFWQVQLLTSLMLFVSNALP
                     NVAGMGSIETAFLLVFGSFLEQGEVMSVLMLYRIASYYVVFAASAVGFFIAQRHLVQME
                     PPKEG"
     CDS             8789..9247
                     /locus_tag="ctg56_54"
                     /transl_table=11
                     /translation="MKSFHIPRTALFFILFALAAFAVLYRPIDLKALVRASSQGTLRTE
                     EVAHFGSTNDMDYHLLSMDSEAFQQTAELLSTVSCRKKLNQNYSAYTHDTFPVQSVTVS
                     FYDDAENQKFLLTVYSDGVCILNNAFVSVKYPGGGAAQLYEQLAGMGK"
     CDS             10001..12253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_55"
                     /sec_met_domain="Gly_radical (E-value: 1.8e-40, bitscore:
                     129.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.5e-267, bitscore:
                     878.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQFEQWEGFEGRIWKEEVNVRDFIQKNYTPYNGDESFLAGPTEA
                     TDKLWGALQQLQKAERAKGGVLDMETEVVSSLTSYGPGYIDDNLKDLEQIVGLQTDKPL
                     KRAFMPYGGIKMAEQACTTYGYQPSAELHKIFTDYTRTHNQAVFDAYTPEMKKARHTHI
                     ITGLPDTYGRGRIVGDYRRVALYGIDALIQFKQEDLANCGDGTMTDDVIRLREEIARQI
                     SALKGMKKMAEAYGYDISQPAKDAKEACQWLYFGYLAAIKTQNGAAMSVGRISTFLDIY
                     IQRDLDKGILTESQAQELIDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVGGIGMDG
                     RSMVTKNCYRFLHTLENMGPAPEPNLTVLYSSALPEAFKKYASKVSVNTSSVQYENDDV
                     MKPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKSHEQCGPNYAP
                     ITSEYLTYDEVLPKYVQMLDWLAGLYVNVLNLIQYMHDKYYYEEAEMALIDTDVRRTFA
                     TGIAGFSHVIDSLSAIKYAKVKVVRDENGLATGFETEGDFPKYGNDDDRADEIGVWLLK
                     TFLEMIKKRHTYRNSEATTSILTITSNVVYGKYTGALPDGRAAFTPFAPGATPSYGAEQ
                     NGLLASLNSVAKLPYHWALDGISNTQTINPEALGHSEGERVENLVQVLDGYFDQGAHHL
                     NVNVFGKEKLLDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVLARTCHGVL"
     CDS             12240..12992
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 63.2;
                     E-value: 1e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_56"
                     /sec_met_domain="Radical_SAM (E-value: 8e-29, bitscore:
                     93.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASCKTLGYVHSLESFGSVDGPGVRFVVFLQGCALRCKYCHNPET
                     WAEGGEPWTAEALFQRVYRYRNYWGKKGGITVSGGEPLRQMDFLTEFFTLARAKGVHTA
                     LDTAGQPFRPDDPAYLAAFDRLMANTSLVILDLKEIDPERHRQLTGKDNANILAMARHI
                     SDLGIPLWVRHVLVPGLTDDEEGLRKTADFIRSLKTVQRVEVLPYHTLGLFKWQKLGIP
                     YPLPDAVPPTAEQVKHAEELLEVSRYPG"
     CDS             13498..14895
                     /locus_tag="ctg56_57"
                     /transl_table=11
                     /translation="MQIFNTLTRQKEEFVPQVPGEYRIYVCGPTVYNYIHIGNARPLIV
                     FDTLRRYLEYRGNKVIYVSNITDIDDKLIKKGQEEGTSMKEVAQRFEAEYLKDAAGLNC
                     EKPTVQPRATEHIPQILDIVKDLIDSGHAYVAKNGDVYFRVKSDPGYGKLSHLNLDDLE
                     SGNRELRSRMEDDLKEDPADFAVWKAAKPGEPAWESPYGMGRPGWHIECSAMSRTHLGK
                     TIDLHCGGQDLIFPHHENEIAQSECANGCEFARYWMHNGFINVDNQKMSKSLHNFFTVR
                     DVANLYGYEPIRYFMLTAGYRMPLNYTVDLIESCKNSLERLYTCRENLDFALSKTDFGT
                     DETLKEKAAEARTKFCTAMDDDLNTPDALAAVFDLVKEINTLSAASSKAALETAAAAFD
                     EITGVLGLLYNRKKDEVPAEVTALVEKRAAAKKAKDWATADAIRAQLTELGWAVKDTAQ
                     GPQLSKL"
     CDS             complement(15187..16404)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     335.1; E-value: 1.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_58"
                     /sec_met_domain="Fe-ADH (E-value: 1.3e-102, bitscore:
                     335.1, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARFTLPRDLYHGKGALEALKSFTGKKAMICVGGGSMKRFGFLDR
                     AVEYLKEAGMEVELFEGIEPDPSVETVMRGAEAMLKFEPDWIIAMGGGSPIDAAKAMWI
                     KYEYPEITFEEMCKVFGIPPLRRKAHFCAISSTSGTATEVTAFSIITDYQKGIKYPIAD
                     FEITPDVAIVDPDLAETMPKKLVAHTGMDAMTHAVEAYVSTAHCDYTDPLAIFAIRMIQ
                     GDLVDSYNGDMSKRDSMHNAQCLAGMAFSNALLGIVHSMAHKTGAAFADYGAHIIHGAA
                     NAMYLPKVIAFNAKDPEAKKRYGVIADEMKLGGANDDEKVKLLIEYLRGMNDALNIPHC
                     IQHYGPDSYPTEQGFVPENVFLERLPEIAKNAIADACTGSNPRQPSQEEMEKLLKCCYY
                     DTEVDF"
ORIGIN
        1 cgccagctcg gtgcttaccc gggctgccgc cgcaatgagg aaggggcaca gcagtgcgcc
       61 gcaggcgtag cagctgtgca tcaggttcat gccccgggtg cggtcggcag aatgatcgct
      121 gaccagaatg gtacaggtgt tgataacgct gcccttggcg atgcctacca caaaaaaggc
      181 cgctgccagc agcgccactg cgccggtcag tcccatgacg gcatagcccg ccgcatagcc
      241 gatggtcagc agcagcacac tgcgcttcat gcccagcgca ctgggcagca tccccatcag
      301 cagccccgcc agcaggttgc cgatgctcat cagggagagc agcgtgccgg tcatgccgta
      361 ggcaaagccg tagcgctcct gcagcaaact gaccaccaca cccgcgctga tggcgcagat
      421 gccgctgaag aaaaaggtcg caaagcccgc attgcgcagg cgcgtgttct gttgttccat
      481 ggtgttcctc tccttgcgga aatatccttt ctctatttaa ccattttttc gcatctttgc
      541 aaccggattt tcttacaaaa agcagcaaaa aaactgccgc acaaaacgtg cagcagtttt
      601 ttcttttatg ataagtattt ctcagtccag atcttccgct tccagcaccg caacgccttc
      661 gctttcaaag gtcttgcgga gggtttcagc cagacccggg ttgggtgcct tgttgtggat
      721 gcacaggatg atctttccgt tcaggctggc agcctccaca cccacggatg caccgtccgg
      781 cggtacccag acgccaaaat ccgtggtgta ctgtgccagc tccggggcgg caggcatgag
      841 cggattgccc agatagctga gccagaagtc cgaaatcgtg ccgccgatgt actcgcccat
      901 ctggaacacc cgctgcttga tgcgcagggg cgctttttgc tggttcacct tgtacaccca
      961 gcccatctgg tcggccatac ggtgacgctt ggactccggc tgcaggtccc gcctgatgtc
     1021 tgcatctaca tcagatacaa aatccgcaag gcgggtctgg gtttgcagct gcaccgtatg
     1081 cccaaagctg cacacgcagt tgtacagcgc attcggcaca ccggccacat cgcgagtatc
     1141 ggaggagtag gaatactgga tcttctcctt gcccagatac tcccgcatgg ccatacacag
     1201 cagacccatc agagcgctta ccggctttgc gttgttcgcc agcgcttttt ccacaaggct
     1261 ctgcttgctc aggcacaccc gggtgcggcg cagcgcaccc tcgtaggtct gcaccacatc
     1321 ccgctggatg acatcgctcc cgtactccac aggcgggtac tctgccagca tggcctccat
     1381 atcatagggc gggtcgcaca cgatctgcgg caccgcaaag gccgtgccgt aacgcaggtt
     1441 gcagtactgc tccagaatgc tggtgagcag gggcgatacc ccgtggccgt ccagcaggaa
     1501 gtgatgccag tcaaagtaga cggtatcccc ttcgcagctg acgcagaaca ggtagccgtt
     1561 cgtctgttcc gggatattgc gcatggtgct gccggggtac acaaggcagg gctccgtatt
     1621 gggctccagc cacatctccc gcttttcctg caccagacgc tgggtataat agggcgcact
     1681 tgccaaggcc gctgtcagtg cccgctgcaa aagggtgata tccaccgcat cccgcagcga
     1741 gaactggtac cggcactgga tcttttcccg acggaaaaag tacatgattc cctgaaagtt
     1801 atattccgtc gagcgctgct gtgtttccat tggtttttac cccacgtttg ctgccagata
     1861 atccaccaga tcacccatgg tgacaaagtt gcgcagctcc ttttccggga tacgcaggcc
     1921 aaaggtctct tcaagatctg ccacaatggt caggatctcc atagaggaca gatccagatc
     1981 gtccatcagg acgctgcttt cggtcacatc ctccggcgat acctctgcga catcctccag
     2041 aatagccgtg atctgagaaa tgatttctgc acgttccatc gtattatgct tcctttctgt
     2101 tgcgttttac ttgcgcacca gcttgcccgc agcgttgcgg ggcagcggcg tttcgctgaa
     2161 ttccaccacg ccaatgcgct tgtacagcgg gacagtgcgg ttcatctggg caataaagtc
     2221 ccgcaccgtc tgctggtgct ccttttcaca gtataccaca acacctatct ttttgcccag
     2281 ttcttttacg atacattcct gtacggcggg acatttttct aacatgccct ccagctcctc
     2341 gggactgacg ttctcgccgc tgtccagaat gatcaggttc ttcttgcggc cggtaatgta
     2401 atagtagccg tcctcgtcca cccgggcaag gtcgccggtg tggaaccagc cgtccttgtc
     2461 gatgaccgca gcggtggcct cggggtcctt gtagtagccc agcatgatgc tgtcgccccg
     2521 gatgcacagc tctccgtccg gctcgagctt gtagtccaga taatcgttgc cctgtcccac
     2581 agcgccgatg tgctttgcat cctgcgcgta gttgatgatg ccatcgccgc aggtctcggt
     2641 agcgccgtag gtctgcacca cgaacatccc gttggtggcc atatccagca tcacctgcgg
     2701 gtcaaacatg gcagaggagc agatgggcac ccacagctcg cccaagcgct ccttgcggcc
     2761 gcgcatcacg tccttgtgca gggagttcat gatcaccggc accaccgcca tgacctgact
     2821 gggcatccgc cggatctcct tatagaaatt gcggatatcg ccgctgatgt tcagcgccca
     2881 gcccccgtgt gcccaggaga acaggcagat gaatgcaccc agatggaaca tgggcagcac
     2941 cgtgtactgg ctgaccacaa gctccgggtc gtgcttatac tccatcatgc gctcaccgat
     3001 ctgcacatgg gcgcgcatca cgctgaagaa gttgcgctcg ctcagcatca cgcccttgct
     3061 gcgtccggtg gtgccggagg tgaacatcag gatcatcagg tcatcgtggc cgatgcagcg
     3121 gggcatctct gccaccggct cataagcgcg gaagccgtcc atggggcgca gaatgctgcc
     3181 gtagtcggcc tgcagctgct ccttggtgcc gtagtcgtcg ccgtcggtca ggatggcagc
     3241 ggggtccacc agccccagct cgtaggacag ctcgtcccag ctcttgtgct ggttgagcag
     3301 taccagtaca ccgcccgcca gaatgatgcc gaaggtgttc acggcatatt cgtagctgtt
     3361 tttattcagc aggcagatct ttttgccctt gatatccggg atggtgctct ggaagtagct
     3421 gaccgcacgg cggatatccc gcgcgtagtc cttataatgg actacggtca cctcgtccgt
     3481 ttccttatca taaaagcgga gcgccacacg ctccgaaaaa cgctgttcca tattcagggt
     3541 gaccagatca tacacgttgt ccaatacctt gatcattgta ttttcctcct gcgttgttat
     3601 ttcatcctgc ggcagtgcgc tgtactgtgc tcagtataca atattttcca atgcaatgca
     3661 atacttctgc aacatttaat ttctcacttt gacaactttc aattgcacat cttgggatac
     3721 gccccggcca aattctacct ttcgttgcaa tccgccggtt ttcgtgctac aatttttagc
     3781 gcaaaatacc agttccggta tggtgcagac tgcaaaacaa aattgacagt ctctataaaa
     3841 agcattatac tagccatata tcatggcaat gctgtataaa aactgatcat ttgcgccgta
     3901 tccggctttt tctcgagggg tattggcccg gcgcagggaa ggaatctttc atggaaacaa
     3961 ccaagccccg cactgtcaac tccatcggga tgtttgatat gctcaagggc gctgggatgc
     4021 tggccatcgt gctgggacac actgcggagc tttacccact ccagctggag ggcggcctgt
     4081 cgctgacggc ctttgtcggc tttatctacc gcgaaacgct gatggcggcc ttttttattg
     4141 ccagcggcta cggcttccgc aagcgctcca tcagcaagtg catccaccag cagctcaaaa
     4201 gcctgctcaa gcccttttgc tacactgcgg tgttcaccac ggtgctgcac ttcatcattc
     4261 attataaaac ctttcactat ctgcccggct ccatgactga gagcatcaag gtggcgggcg
     4321 gctttctgct gggtctgccc catactgcca cctacttcag gcaggagttc ttttcctgtg
     4381 ggcccatgtg gtatctactg gcgctgttga tgggctggat cttactggac gttatcctga
     4441 atatcttccc ggagcggtac attccctggg cggtgggcgg tgccgccctg ctgggctggg
     4501 gtgccagcct tgtatgggag ctgcccttct gcctgatcca gggcgcggtg atcacgccgt
     4561 acctgtacct tggctacctt gccaaacggc agcattggct ggatcagcct ttgtcccgcc
     4621 ggatgtcctg catcctgtgg gcagccgtac tgctgatccc ggcagccgcc cttgccaccc
     4681 gccgcaccga ctgtgtatcc atggccgagt ggtcgctggg tcccatcagc atcctgctgg
     4741 acggccttgc cggtctgctg tttatccggc tgtttttgcg ctggagccag cgccgcaacc
     4801 cgctggtgcg ctttttcgag gccatcggcc gccgttccct gtacatcttc tgcgtacata
     4861 cggtggagtt gatcgccatt ccgtggtatc tgttcgccgc caaatacgcc gaccgccctg
     4921 ttttgggcat cagcctgcaa tacatccttt cgctgggctc catctggctg atctgcgccc
     4981 tgctgcagcg gcggcgggat ctgatcatca agttgttccc cgcccggcgg cgcacccctc
     5041 aggtacatta cgccccgcgg cactgatttt tctgaatgtt ttggctgcgg cggtgcagct
     5101 gttataggat aaaggaagag gaggatcccg ttatgaacca cgatgccccc atgacccctg
     5161 ctgccatgca ggcgcacatt gccgagctgg agcagcagct caagctttcg gacgagggtg
     5221 tttcccagct ggcgcagcgg tgtctggagc tggagcagca gctgctggct tgccagaccg
     5281 agcttgccaa gcacagcgcc gaggctgaga atatcaccct taccctgccg cagctgttct
     5341 acgacaccgg cagcggcttt tcgccccggg aatgcctgac tgccaccgag gatgtctaca
     5401 acgaactgac ccacgaggtc tcggtcacct ttgtcctgcc ggaggacgca cgcgccatcc
     5461 gtctggaccc cggcgagctg gcctgctgca tcaccgacct tgccatctcg gacgaacgca
     5521 tcagcttcca gtcggtcaac ggccttctgt tgcaggagga cagcctgctg tttttggacg
     5581 tagaccccaa cctttcgctg cactgcacca ccggctttgg tgtcggcatg aagtttgcgg
     5641 tgaactatca ctactacccg ctgggacgtt ttctgcacga gcagcccggc aagtctctgc
     5701 tgcgggcgct gaacgacctg aagcttgaga acgccgctgc cgcgcaggag gcagaggaag
     5761 tattgcaggc cagccgcgcc gagtgtatgc ggctgaacca gcagctgctg accttgcagg
     5821 gcatccagca cgaatatcag gtttcgctgg aaacgatgcg cgccagcagc agctggcggc
     5881 tgaccgcccc gctgcgcaga ctgctgaacc tagtgcgcgg tcactgagcc cgcccgatat
     5941 tctgcccgga ggagttggat catgtacacc agttacagta ccctgcagcg caagcaattg
     6001 tccaagcagg tctataccga tacccagagc acctatcttc tggtctacgc gccggggcgt
     6061 cacaaggcgc tgcaagcggc gctgcaaaac cagctgcacc gcaagttccg tctggtgacc
     6121 cagcttgagg acgagctgac ccccgatgta gccggggtgc tgctggtaag cgaggatgtg
     6181 gagtgcaccc ccaccgccct gacctatttt gccgccgccc tgcgtgaggg cgcagacctt
     6241 gcggtctgcg acgcctcctt tggctttgac ggctccaccg ccctgtacct gagcacccgg
     6301 cacctgcccg gcagcagctg cgcactggtg tctcgcgcat tgctggacaa ggtacgcgcc
     6361 gccgcccggg gcaaggacag cgttaccgaa ctgctgcgtc tggcccacgc catggcgcag
     6421 cacagccgct gcatcccgca ggcgctgctg cacttccgcc gggagctgtg cgccgacgat
     6481 gtattctccg ccaagggacg ccgtgcgctg attttgagcc atgagctgac catgaccggt
     6541 gcgcccatcg tgctggtaag tgccgtgccg gtgctgcgca gcttaggctt tgaggtggtg
     6601 gtgctgggac cctcggatga aggctcgctg ccgctgtttc tggacgccgg ggccgctgtg
     6661 gtcacccgcc cggactgcgt tacttccagc gccctgtggg ggctggccac cagcgcagac
     6721 tttgtgctgg ccaacacggt ggtggaagcg ccggtggtga acaccctgaa cggctccttt
     6781 gtgccggtgc tgtggtggct gcacgatgcc tttgcgggct accccttcat ctcccacagc
     6841 atccccaagg cgctgggcaa aaacgtgcac ctctgcgccg taggctccca cgccaccgcc
     6901 gccatgcact ccgtccggcc ggattttgaa atcgagcagc tgatctacgg tctgccggac
     6961 tatgcagccg agcaattccc ccgctatgac atcagctttg ccggggggcg tcccctcttt
     7021 gtgacggtag gctcgctgga acaccgcaag ggtccggaca tcttctgcaa cgccatccgg
     7081 ctgctgccct ctgcagtgcg ggaaaaagct gccttccttt ttgtgggcaa agccgccgac
     7141 aaggggatgt acaacgccgt ggacagcttg gtgcgggact atccccagac cgttttctac
     7201 cgcaagcggc tggagcgccc ggaggtcaaa tccctgatgg agcagtgcaa ctgcgtggtg
     7261 tgcgcctccc gggatgaccc catgcccacc ttcgtcaccg agggactgat cttcggcaag
     7321 ccctccatcg tatcggagca caccggcacc gccgggctgg tgaccgaggg cgtggacggc
     7381 ttcctctaca aggacgacga cccgcagcag ctggccgata agctgacttg ggccatcgag
     7441 cacccggagg cactggccgc catgcacggc agttgccgcc gcctgtacga gcagcagttc
     7501 tccaacgaat cctatgtcgc taccctgaca aggctggtaa aagagctgac ggacggggaa
     7561 gaatcatgaa aaaacaatgc cggacagctg cacgctgccc ggcattgctt tttcacggga
     7621 gaggtttccc cattttatca aatcccccaa attgcccaac aaagttccgc ttccgttcac
     7681 aaagggcggc gggagatgtg ctatactgat tccagaattt ccggttgtga aaggagtttt
     7741 gtttccatga gccaagccgc cgcgcagcag ccctcccgca aaaaggccgt gatctctctg
     7801 ctggtgctgc tggcacttac ctgcatcatt gtgttcactt ttaaggatca ctgggccgag
     7861 atcactgcgg cgctggcgca gctttcggtg tggcaggtgc tggcggtgct ggcggtcggc
     7921 ctcagctacc ccctgctgga ggggtgcgtg gcgtgggtca tcgtgcgcag ccgtctgccg
     7981 cagttcaccc tgcggcaggg gctggatgtt ggctggtgcg gcacctttgg caacgtggtc
     8041 acgctgggtg ccggtgcggt gccggtgcag ctgtactacc tgcacaaggc cgggctgccg
     8101 ctgggccccg gcgcaggcct gatgacgttg gaatacgttt tccacaaaag cacggtgctc
     8161 ctgtatgcca ccgtgatgct gctgttgcag cgccgctggc ttgccgccaa caccactggt
     8221 gtcatgcgct acctgcccat ggcatacgct gtggtagcgg taattatcgt ggcgctggtg
     8281 ctgctgtgcg tctcgccgct ggtgcagaac ctcgcccgct ggctgctggg ctttctgccc
     8341 aagaccgaaa agtggcagca gcgccgcgcc gactggctgg agcagctgga agtgctaagc
     8401 accgagagcc gccgactgct ggcagataag ccccgctgcc tgaaaatttt tgccctgcag
     8461 gcgctcaagc tgttcgggct gttctgcctg ccctacctgt gcatccggtt catggggctt
     8521 tcgccgctgg gcttctggca ggtgcagctg ctcaccagcc tgatgctctt cgtttccaac
     8581 gctctgccca acgtagccgg gatgggctct atcgaaacgg cctttctgct ggtgttcggc
     8641 agctttctgg agcagggcga ggtgatgagc gtgctgatgc tctaccgcat cgccagctat
     8701 tatgtggtat ttgccgccag cgccgtgggc tttttcatcg cccagcggca tcttgtccaa
     8761 atggagccgc caaaggaggg gtgagcagat gaaaagcttc cacattcccc gcaccgcttt
     8821 attttttatc ctgtttgcac tggcagcttt tgcggtgctg taccgcccca tcgacctgaa
     8881 agcactggta cgcgccagct cgcagggcac gctccgcacc gaggaagtgg cgcattttgg
     8941 cagcacaaac gacatggact atcacctcct ctccatggac agcgaagcgt tccagcaaac
     9001 ggcagaattg ctttccaccg tctcctgccg caaaaagctg aaccagaact attctgccta
     9061 cacccacgat accttcccgg tgcagtcggt caccgtcagc ttttatgacg atgccgaaaa
     9121 ccagaagttt ctgctgacgg tgtactccga cggcgtgtgc atcctgaaca acgcctttgt
     9181 cagcgtaaaa taccccggcg gcggcgcagc gcagctgtat gaacagctgg cggggatggg
     9241 gaagtaaaaa cgaaactccc ccagtctgct cccgctggtc gcagccagcc ccctcggaga
     9301 tggggccttt ggcatagcgg cacagtttcc tgttaaaccg gaaagttttc cgttgcgcca
     9361 gaggctccct cccagaggga gctggctttg cgcagcaaag actgagggag tttcctcgca
     9421 aaacaaaaat cggggcactc aggtggtcaa gctgagtgtc ccgtttttgt tttctttgcg
     9481 tcggctgtgg taccaaacac agccggtgcc gcgccggaag ctgcagagca aaccgtgctg
     9541 ccgcttcccg tagaaaagag aaaggaatgg aggaatggag cggagcgctt gcagacgctc
     9601 ctttttttct ggtgcaacgt ggttagaatt agctaaccac cgctgcgaga acaggatacc
     9661 acagacggtt agtcttgtca acccttaatt tgcaaatttt ttcgcaaatt gtgtgcaccg
     9721 ccggggtttc ggcgtttttt ctacattctg cccaaagaaa gccctttgct ttggaagaaa
     9781 acccacttgt tttctattgc tttttaaagc ggttcttgct attatagtaa cgcaagattt
     9841 tgtgggcagg tttttatttt tgtctacacc ttgtagtaag ggctgccgca gccggcagcg
     9901 caagaccgtt tcgcccccag aaaaccgccc agacagagcg gtttttcaaa ggctcattag
     9961 ttagaaaacg ctaactgcgt aatggagcaa ggaggttcca atgatccagt ttgaacagtg
    10021 ggaaggcttt gaaggccgca tctggaagga agaggtcaat gtgcgtgact tcatccagaa
    10081 aaactacacc ccctataacg gtgacgaaag ctttctggca ggccccaccg aggctaccga
    10141 taagctttgg ggtgctttgc agcagctgca gaaggccgag cgcgccaagg gcggcgtgct
    10201 ggatatggag accgaggtgg tcagcagcct gacctcctac ggccccggct atattgacga
    10261 caacctgaag gatctggagc agatcgttgg cttacagacc gacaagcccc tcaagcgcgc
    10321 ctttatgccc tacggcggca tcaagatggc agagcaggcc tgcaccacct acggctacca
    10381 gccctctgcc gagctgcaca agatctttac cgactacacc cgcacccaca atcaggctgt
    10441 gttcgatgcc tacacccccg agatgaagaa ggcacgccac acccacatca tcaccggcct
    10501 gccggatacc tacggccgcg gtcgcatcgt gggcgactac cgccgcgttg ccctgtacgg
    10561 catcgacgcc ctgatccagt tcaagcagga ggatcttgcc aactgcggcg acggcaccat
    10621 gaccgatgac gtcatccgtc tgcgcgagga gatcgcccgc cagatcagcg ccctgaaggg
    10681 catgaagaag atggccgaag cctacggcta cgacatctcc cagcccgcca aggacgccaa
    10741 ggaagcctgc cagtggctgt acttcggcta tctggccgcc atcaagaccc agaacggcgc
    10801 cgccatgagc gtgggccgca tctccacctt ccttgacatt tatatccagc gcgatctgga
    10861 caagggcatc ctgaccgaaa gtcaggcaca ggagctcatc gaccacatgg tcatgaagtt
    10921 ccgcatggtc aagttcgccc gcatccccag ctacaaccag ctgttctccg gcgaccccgt
    10981 gtgggcgacg ctggaagtgg gcggcatcgg catggacggc cgcagcatgg tcaccaagaa
    11041 ctgctaccgc ttcctgcaca cgctggagaa catgggcccc gcaccggagc ccaacctgac
    11101 cgtgctgtac tcctctgccc tgccggaggc ctttaaaaag tacgcctcca aggtatctgt
    11161 caacaccagc agcgtccagt acgagaacga cgatgtgatg aagcccgtct ggggcgatga
    11221 ttactccatc tgctgctgcg tgtctgccac ccagaccggc aaggagatgc agttcttcgg
    11281 cgcacgcgcc aaccttgcca agtgcctgct gtacgccatc aacggcggcg tggatgagaa
    11341 gagccatgag cagtgcggcc ccaactacgc ccccatcacc agcgagtacc tgacctatga
    11401 cgaggtgctg cccaagtatg tgcagatgtt ggactggctg gcagggctgt acgtcaacgt
    11461 gctgaacctc atccagtata tgcacgacaa gtactactat gaggaagccg agatggcact
    11521 catcgacacc gatgtgcgcc gcacctttgc caccggcatt gcaggcttct cccatgtcat
    11581 cgactccctg agcgccatca agtacgccaa ggtgaaggtg gtgcgtgatg aaaacggcct
    11641 tgccaccggc tttgagaccg agggcgactt ccccaagtac ggcaacgatg acgaccgcgc
    11701 cgacgagatc ggcgtgtggc tgctcaagac cttccttgag atgatcaaga agcgccacac
    11761 ctaccgcaac tccgaggcta ccacctccat cctgaccatc acctccaacg tggtgtacgg
    11821 caagtacacc ggcgctctgc cggacggccg cgccgccttc accccgtttg cccccggcgc
    11881 tacccccagc tacggcgcag agcagaacgg tctgctggcc tcgctgaact cggtggcaaa
    11941 gctgccctac cactgggcgc tggacggcat ctccaacacc cagaccatca accctgaagc
    12001 gctgggtcac agcgagggcg agcgcgtgga gaatctggtg caggtgctgg acggctactt
    12061 tgatcagggt gcacaccacc tgaacgtgaa cgtctttggc aaggagaagc tgctggacgc
    12121 catggagcac cccgagaagg aagagtacgc caactttacc atccgcgttt ccggctacgc
    12181 cgtcaagttc atcgacctga cccgcgagca gcagctggac gtgctggcac gcacctgcca
    12241 tggcgtcctg taagaccctt gggtacgtcc actcgctgga atccttcggc tcggtggacg
    12301 gccccggcgt gcgctttgtg gtgtttttgc aggggtgtgc cctgcggtgc aagtactgcc
    12361 acaaccccga aacatgggca gagggcggcg agccgtggac ggcggaagcg ctgttccaac
    12421 gggtataccg ctaccgcaac tactggggca aaaagggcgg catcacggtc agcggcggcg
    12481 agccgctgcg gcagatggac tttctgactg agttcttcac gctggcgcgt gccaagggcg
    12541 tgcacacggc gctggacacc gccgggcagc ccttccgccc ggatgacccg gcctatctgg
    12601 ccgcatttga ccgtctgatg gctaacacca gtctggtgat cttagacctc aaggagatcg
    12661 acccggagcg ccaccggcag ctcaccggca aggacaacgc caacatcctt gccatggcgc
    12721 ggcacatctc cgacctcggc atcccgctgt gggtgcggca cgtccttgtg cccgggctga
    12781 ccgatgacga ggaggggctg cgcaaaacgg ctgactttat ccgctcgctc aaaacggtgc
    12841 agcgggtgga ggtgctgccc taccacacct tggggctgtt caagtggcaa aagctgggca
    12901 tcccctatcc cctgccggac gctgtaccgc ccacggcaga gcaggtaaag cacgcagaag
    12961 aactgctgga agtgagccgg tatcccgggt aaagcaccac cgttttgatt gcgctccgct
    13021 tcgctctgcg cccttcccgt gaaaatggga tatcggaacg cccgcaggcg ttccgatatc
    13081 ccgaaattta aaataattct tccgctgagg atgcccaaag caacgcggag ggcattctga
    13141 atcgttcttt gttgtacctt gacttccctg caccgcaccg ctataataaa ggggtaaaag
    13201 gataaatgcg tttatccggg cagagtagcg ccgcacaccg tctgcgcaga gagaacaggc
    13261 cactggctgg aagcctgttt gcagaccgct gcgcaaagtg cgcccggaca gcacgcggcg
    13321 ggaacccctg cggggaagta tcgccgtgcg gtgcgccgcc gttaccggct ttgagcgaca
    13381 aacagaagtg gaaccgcgat tttgatttta aaaccgcctt cggagctgtg ccttgcgcac
    13441 cgctccgggg gcgttttgtt ttgcggcttc tgtttggaac aaaaaggaga attgaccatg
    13501 cagatcttca acaccctgac ccgacagaag gaagaatttg tgccgcaggt gcccggcgag
    13561 taccgcatct acgtctgcgg ccctaccgtg tacaactata tccacatcgg caacgcacgc
    13621 ccgctgatcg tgttcgacac cctgcgccgc tatctggaat accggggcaa caaggtgatc
    13681 tacgtttcca acatcaccga tatcgacgat aagctcatca agaagggaca ggaagagggc
    13741 acctccatga aggaggtggc gcagcgcttt gaggccgagt acctgaagga tgccgccggt
    13801 ctgaactgcg aaaagcccac cgtgcagccc cgcgctaccg agcatatccc ccagattttg
    13861 gatatcgtca aggatttgat cgactccggc cacgcctacg ttgccaaaaa cggcgatgtg
    13921 tacttccggg tgaaaagcga ccccggctac ggcaagctga gccacctgaa tctggacgat
    13981 ctggagagcg gcaaccgcga gctgcgcagc cgcatggagg acgatctgaa ggaagatccc
    14041 gccgactttg ccgtctggaa ggctgcaaag cccggtgagc ccgcatggga aagcccctac
    14101 ggcatgggcc gcccgggctg gcacatcgag tgcagcgcca tgagccgcac ccatctgggc
    14161 aagaccatcg acctgcactg cggcggtcag gatctgatct tcccccacca cgaaaacgag
    14221 attgcccaga gcgagtgcgc caacggctgc gagtttgccc gctactggat gcacaacggt
    14281 ttcatcaacg tggataacca gaaaatgtcc aagagcctgc acaacttctt taccgtgcgg
    14341 gatgtggcaa acctctacgg ctacgagccc atccgctact tcatgctgac cgccggctac
    14401 cgcatgcccc tgaactacac cgtagacctc atcgagagct gcaagaacag tctggagcgc
    14461 ctgtacacct gccgcgagaa tctggacttt gccctgagca agaccgactt cggcaccgat
    14521 gagactttga aggaaaaggc cgccgaggca cgcaccaagt tctgcaccgc catggacgac
    14581 gacctgaaca ccccggatgc actggctgct gtgtttgatc tggtgaagga gatcaacacc
    14641 ctgtccgccg cttccagcaa ggctgcactg gagaccgctg ccgccgcctt tgacgagatc
    14701 accggcgtgc tgggtctgct gtacaaccgc aagaaggacg aagtgcccgc cgaggtgacc
    14761 gcgctggtgg agaagcgtgc tgccgccaag aaggccaagg actgggccac cgctgatgcc
    14821 atccgcgcac agctgaccga actgggctgg gctgtcaagg acaccgcaca gggtccccag
    14881 ctgagcaagc tgtaacgcct gccgctgcgg gagaaccatt ttgaatggcc tccgcgctgc
    14941 tctggccata attcaaggaa ttataattta gaattggggg ttcagaaacg cctgcgggca
    15001 tttctgaacc cctttttcac agctggggtc tcaatctcgt gaaaatgcaa tgtcggagcg
    15061 tccgcagacg ctccggcatt gctctattaa aaataatttt ttccgcaacg gcaaaagccc
    15121 cgcagggcgg tatgctctgc ggggcttttg tccataggga aggaggcgta ataaagaaag
    15181 gacggatcag aaatccacct cagtatcgta gtagcagcac ttgagcagct tctccatctc
    15241 ctcctgactg ggctggcggg ggttggagcc ggtgcaggcg tcggcgatgg cgttcttggc
    15301 gatctcgggc agacgctcca ggaacacatt ctccggcaca aagccctgct cagtggggta
    15361 ggagtccggg ccgtagtgct ggatgcagtg ggggatgttc agcgcatcgt tcatgccgcg
    15421 caggtactcg atgagcagct tgaccttttc gtcatcgttt gcgccgccca gcttcatctc
    15481 gtctgcgatg acgccgtagc gcttcttagc ctcggggtct ttggcgttga aggcgatgac
    15541 cttgggcaag tacatggcgt tggcagcgcc gtggatgatg tgtgcgccgt agtctgcaaa
    15601 ggcagcgccg gtcttgtgcg ccatggagtg cacgatgccc agcagtgcgt tggagaaagc
    15661 cataccggca aggcactggg cgttgtgcat ggagtcgcgc ttggacatat caccgttgta
    15721 gctgtccacc agatcgccct ggatcatgcg gatggcgaag atggccagag gatcggtgta
    15781 gtcgcagtgt gcggtggaaa cataagcctc cacggcatgg gtcatggcgt ccataccagt
    15841 gtgggcaacc agctttttgg gcatggtctc agccagatcg gggtccacga tggccacgtc
    15901 cggggtgatc tcaaagtccg cgatggggta cttgatgccc ttctggtagt cggtaatgat
    15961 ggagaaagcg gtcacctcgg tggcagtgcc ggaggtggag gaaatggcgc agaagtgtgc
    16021 cttgcggcgc agcggcggga tgccgaacac cttgcacatc tcttcaaagg tgatctcggg
    16081 gtactcgtac ttgatccaca tggccttggc tgcatcgatg ggagagccgc cgcccatggc
    16141 gatgatccag tcgggctcaa acttcagcat ggcctcagca ccgcgcatga cggtctccac
    16201 ggaaggatcg ggttcgatgc cctcgaacag ctccacttcc atgccggctt ccttcaggta
    16261 ctccacagca cggtccagga agccgaaacg cttcatggag ccgccgccga cacagatcat
    16321 tgcctttttg ccggtaaagg atttcagcgc ttccagagcg cccttgccat ggtacagatc
    16381 acggggcaga gtaaaacgag ccataataca aaacctccaa aaatagtacg gcacacgcag
    16441 cgctgtaccg cagttcatta ttatgttaat tatataacaa tttggaggca gcttcaattg
    16501 acataccaag agaaaaagtc gttctatttt gggcggtttc cacaagcagt aggatgcaac
    16561 aagccccctg ccctgaaaaa gcgcaaaaaa acaccccgaa gtcctaagac ttcgaggtgc
    16621 ttgcctttgg agctgctatc cagattcgaa ctggagacct catccttacc aaggatgcgc
    16681 tctaccaact gagctatagc agcaaatggc gacccggatc gggctcgaac cgacgacccc
    16741 cagcgtgaca ggctggtgct ctaaccaa
//
