GCA_036318285.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaAKBLEHKO_4 (original name was: gnl|Prokka|AKBLEHKO_4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	RRE-containing	259,581	277,755

gnlProkkaAKBLEHKO_11 (original name was: gnl|Prokka|AKBLEHKO_11)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	arylpolyene	62,179	109,717	flexirubin	Other	36%

gnlProkkaAKBLEHKO_15 (original name was: gnl|Prokka|AKBLEHKO_15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	RiPP-like	1	9,935

gnlProkkaAKBLEHKO_17 (original name was: gnl|Prokka|AKBLEHKO_17)

Region	Type	From	To	Most similar known cluster		Similarity
Region 17.1	resorcinol	63,382	104,521

gnlProkkaAKBLEHKO_29 (original name was: gnl|Prokka|AKBLEHKO_29)

Region	Type	From	To	Most similar known cluster		Similarity
Region 29.1	NRPS	32,869	73,423

Region	Type	From	To	Most similar known cluster	Similarity
Region 4.1	RRE-containing	259,581	277,755
Region 11.1	arylpolyene	62,179	109,717	flexirubin	Other	36%
Region 15.1	RiPP-like	1	9,935
Region 17.1	resorcinol	63,382	104,521
Region 29.1	NRPS	32,869	73,423

Compact view

gnlProkkaAKBLEHKO_4 - Region 1 - RRE-containing

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Location: 259,581 - 277,755 nt. (total: 18,175 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAKBLEHKO_11 - Region 1 - arylpolyene

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Location: 62,179 - 109,717 nt. (total: 47,539 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

gnlProkkaAKBLEHKO_15 - Region 1 - RiPP-like

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Location: 1 - 9,935 nt. (total: 9,935 nt) Show pHMM detection rules used

Region on contig edge.

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAKBLEHKO_17 - Region 1 - resorcinol

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Location: 63,382 - 104,521 nt. (total: 41,140 nt) Show pHMM detection rules used

resorcinol: DarB

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaAKBLEHKO_29 - Region 1 - NRPS

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Location: 32,869 - 73,423 nt. (total: 40,555 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 32868 - 73423:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg29_56

AMP-binding (8..447): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DYFGSGSLIK
Nearest Stachelhaus code(s):: Ala DMGGFGCLIK (50% 8Å match); Leu DYFTFGLIIK (41% 8Å match); Hpr DYQYCGHLIK (32% 8Å match)
Stachelhaus code match:: 60% (weak)

AMP-binding (1210..1629): X

nrpys: Tyr, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMTNMGEVAK
Nearest Stachelhaus code(s):: Asn DMTKVGEVGK (56% 8Å match)
Stachelhaus code match:: 70% (weak)