LOCUS       c00048_gnlPro..        12478 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OIJJHOIG_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 21:14:45
            Original ID  :: gnl|Prokka|OIJJHOIG_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12478
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12478
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[85:6553]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      86..6553
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..12478
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12478
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(86..775)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_1"
                     /sec_met_domain="Nitrate_red_gam (E-value: 9.1e-78,
                     bitscore: 250.4, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGWSIFLWVIYPYIMLASFFIGTFVRFKYFHPSITAKSSELFE
                     KKWLMIGSVTFHIGIILAFFGHCLGMFIPASWTAYFGITEHMYHIFGSLMMGIPAGILA
                     FVGIAILTYRRMTCSRVYKTSDINDIIVDWALLITIALGLACTITGAFIDYNYRTTISP
                     WARSLFVLNPQWQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVY
                     RRRARVY"
     CDS             complement(768..1346)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_2"
                     /sec_met_domain="Nitrate_red_del (E-value: 1.1e-09,
                     bitscore: 28.1, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIDFRRLTDLKDTFAVLSRLIDYPDAETFSPEIRQLLLTDNALST
                     ATRGELLSLFDELAALSSIEVQEMYAHLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIGDGTYTLLKNAVT
                     DSDNPYIQLLRLTRSLIGSCIKMEVREDA"
     CDS             complement(1339..2898)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_3"
                     /sec_met_domain="Fer4_11 (E-value: 2.5e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00039, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 2e-28, bitscore:
                     87.7, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVARPKSQITGEGMELTTGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPEVVKQALKDGISEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMIFPGIDQMRVPVQYLASLLTAGN
                     VPAIKKALYKLAMMRLYMRAKTSGRDFDSSKLERVDLTEERATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQTEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             complement(2888..6553)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_alph_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_4"
                     /sec_met_domain="Molybdopterin (E-value: 3.6e-142,
                     bitscore: 463.9, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 6e-24, bitscore:
                     74.0, seeds: 74, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_alph_N (E-value: 8.3e-09,
                     bitscore: 25.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRFFNKVDKFNGTFTQLEENSRRWEKLYRQRWAHDKVVRTTHG
                     VNCTGSCSWNVYVKQGIITWEHQATDYPSCGPNIPGYEPRGCPRGASFSWYEYSPVRIK
                     YPYIRGKLWELWTAAKEEHENPLDAWASIVEDPEKSKKYKKVRGHGGLIRVHRYEALEM
                     ISAACLYTIKKYGPDRIGGFTPIPAMSMMSFSAGARFIALMGGEQMSFYDWYADLPPAS
                     PQVWGEQTDVPESAEWYNSSYIIMWGSNVPLTRTPDAHFMTEVRYKGTKIVAVSPDYAE
                     NVKFADDWLAPEPGSDSAVAQAMTYVILDEFYQKHPVKRFIDYSKRFTDLPFMVELEPS
                     TANGDHYTPGRFVRISDLVDDDTIVNPAWKTVVYDQNNHKIVVPNGTMGQEYNAKEKWN
                     LELLDQNGNKIDPVLSINDQDGETEQIVADFPAFSNDGNSVVQRHLPVKKLKFTDGKEH
                     LVTNVYDLMMAQMGINRTGNDELAAKDAMDAESYFTPAWQESRSGVKAEQVIQIAREFA
                     QNAAENEGRSMVIMGGGVNHWFNADMNYRNIINMLMLCGCVGMTGGGWAHYVGQEKLRP
                     QEGWANITFANDWEKGGARQMQGTTWYYFATDQWRYEEIDNQAQKSPVWKSKHSYLHNA
                     DYNQMAIRLGWLPSYPQFDRNPLSFAKDYNTTDINEISKKVVDELKKGSLHFAAEDPDA
                     NQNQPKAFFLWRSNLFASSGKGAEYFMKHLLGAENGLLAKPNDRVKPQDMIWRDKGAIG
                     KLDLVVDMDFRMVSTPMYSDVVLPAATWYEKKDLSSTDMHPFIHPFNAAVSPMWESKSD
                     WQQFKLLAKTVSEMAKKYMPGTFYDLKSAPLGHNTQGEIAQPYGEIKDWKNGETEPIPG
                     KTMPSLKLVTRDYTKIYDKFITLGPNIVNNYGYKVDDQYDYLKGMNGIASEGIGAGCPL
                     LDEDEKVCDAILRMSTASNGKLADRAWEKKQERTGEHLTDIGRGHADDSMSFKQITAQP
                     QEAYPTPIGTSAKHGGARYTPFSLMTERNVPTFTLTGRQHYYLDHEIFREFGENMATYK
                     PSLPPVVMAPGDVDVPPVEDEVTLKYMTPHGKWNIHTMYYDNLEMLTLFRGGPTIWISP
                     QDANKIKVKDNDWIEVYNRNGVVTARAVVSVRMPEGSMYMYHAQDNEIYEPLSTITGNR
                     GGSHNAPTQIHVKPTHMVGGYGQLSYGWNYYGPTGNQRDLYANVRKLKKVNWSED"
     CDS             6698..7717
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MNRYDRQERVHQIGSIGQQKISHATIMIVGVGALGSYTAEQLVRA
                     GVKRLVLIDPDTVDVTNLQRQSLFTEEDASKQRLKVEAAKEHLHKINSACQITAIPAPI
                     TADLIDEYQFTLCLDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQKHPC
                     LNCLFPNINELKQNDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELITVDNWS
                     MQFSKFAINKNHHCPACAKPSSISLEEESGPELHMLCGENAYYTVKEKPINFGRLKEFL
                     AKKELLINANRLFLHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFKSLNILMKEDLL"
     CDS             7714..8211
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="MoCF_biosynth (E-value: 6.6e-33, bitscore:
                     103.1, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIAMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQAIDIIITNGGTGIAQRDVTIPAIRPLLKCLIPGFGEAFRQISFDEI
                     GTRALASQALAGFNFRNQLTYCLPGSQNACQTAINKLILPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             8201..9418
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="MoCF_biosynth (E-value: 1.6e-23, bitscore:
                     72.7, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 1.9e-13, bitscore: 40.2,
                     seeds: 41, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_N (E-value: 3.7e-39, bitscore: 123.7,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRIPISVAEAQKKINEIPLKTATETIPLSEANHRVLAKDVHA
                     NYDYPHFRRAGMDGYAILASDDHDFPREFNVRGEIQAGATWDQPLQSGDAVRIMTGAYV
                     PSDVGKVIRIEKTRPAKDENKVQIITTESKTNITEAGTDVKSGDIVLAKDQEINPGGLA
                     VLTAFGVQEVTVYKKPRIAIIATGTELLGPNATIEPGKIFNSNGIMLKNLVEETGGIVD
                     FETQLPDDADLIKQTLEEQIATHEIVITDGGVSVGDFDFIGDEARKADELLFNKIKQRP
                     GSVTTAFVQNSTLIMALSGNPGACFTGFYLYMEPLIRRYQHQASRIKQVRAILAAPYNK
                     TNGFDRYLRCTYEFKDNQFYVYPNGINRSGSLANLQTTTCLALIPHSTTPMKVGTETDT
                     WLLPFK"
     CDS             9397..9888
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLITTTLIERLSKEGYRVAALKHDAHNAAM
                     DVPTTDSARMSSAGAKQVILQSATEFFLHQKSNVPSLTEMVELLSTDNDFVLIEGHKEA
                     TQYPQILLLKPGENPTNVAHTPPLKTGSIFNGTTADLLGKDAIVNWCYDYLKQVKGDAE
                     "
     CDS             9885..10457
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MIGLVYAGGKSTRFGKDKATYHVPGLPATNIELAVEKLTPLCQQI
                     VVCANEINRAHILKLVGQEPAVQIICDIPPYDHHGPLSAIIACTSHFSTLQDYLTLAVD
                     YPYLTKDSLAVLARTSNSYIATSQHSHYSLAHFSISNEQVTTWVADNDDWRLRSFIINK
                     CVSHPLVYRSSAEFSNLNYREVDLNEK"
     CDS             10447..10731
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVNQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPEFDFSATKYFQGPSMGLPRHP"
     CDS             10882..11940
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="VLETANWIQKYFNQSPDAIFLFKNDDLLVSNEPAQRLVTMLNLDV
                     NYLLQIGKNAWSQLENDDCASCLIKKRLKGAAVPITFHSNATHPFHFSMVYRPLDDKEN
                     VFALTLENREQQQRLSQVEEHRILNQYVNEAHEKERQKISQDLHDSVAQGIYAAIMGIQ
                     RLATVQNQRNTEQFQSMSAAIEKQLQTTLKEIKGLALDIRPSVLDNFGLIPAIKALAKR
                     LQNSTGITINVIALTSAEKLQKNIQNVLYRITQEAINNAIKHAHSTEISIIVTDHNSYL
                     QLEILDNGIGFDVDQHSGFNGHSLGLMNMNERVKAYNGAFTITSKINKGTTVKVKFPYN
                     NALNKDMVRTNV"
     CDS             11933..12478
                     /locus_tag="ctg48_12"
                     /transl_table=11
                     /translation="MYNVLVADDHAIVRSGISYLVDLQPNFTVVDGTASGTDTYIRVEQ
                     GGIDILIMDLSMPPGENGLITTRRIHDKFPKVKIIILSMHEEQEYINKAMANGAMSYIL
                     KSSPDSEIVNALKHVINGEKYLDANIIVSKTDIREINASGNTLKLKGYNSLSKREKEVF
                     PLIALGYSNKEISQKMFIS"
ORIGIN
        1 gaacaaatcg cgaataatcg taatataaaa gcatcagaat ttccctgtaa agaaatctga
       61 tgcttttatt atatcttctt atatactaat aaacccttgc acggcgccga tagacaataa
      121 aacgacggaa aatatattgc caaggtagcg ttaaagcatg aaccaaccgg gtgtatggga
      181 agtaaccaaa aattgctaat ccacagagaa cgtgaatttt ataaattaat ggcactgaac
      241 gcatcaattg ccattgagga ttaagaacaa ataggcttct tgcccatgga ctaattgttg
      301 ttcgatagtt gtaatcgata aatgcacccg taatagtaca tgctagacct agtgcaattg
      361 taatcagtaa agcccagtcg acaataatat cattgatatc acttgtctta taaacacgag
      421 aacaagtcat tcgtcgataa gtcagaattg caattcccac aaacgcaagg atccctgctg
      481 gaattcccat catcaatgac ccaaagatgt ggtacatatg ttcagtgatc ccaaaataag
      541 ctgtccaact tgctggaata aacattccta agcaatgacc aaagaaagct aaaataattc
      601 caatgtggaa agtaacgctt ccgatcatta gccatttctt ttcaaaaagt tcgcttgatt
      661 tggcagtaat tgagggatga aaatatttaa atctaacaaa tgttccaatg aaaaatgatg
      721 ccaacattat atatggataa ataacccata agaaaattga ccagccatta tgcatcttct
      781 cgcacctcca ttttaataca cgaaccaatt aatgaacgtg taagcctgag taactgaata
      841 tagggattat cactatctgt cactgcattt tttaaaaggg tataagttcc atctccaatc
      901 acacttaatg ctaattggat atcctgacga cgcggatcat tagtataatc gccatatgct
      961 agaaattcta acaatagagg caaataatca gaaagttcac tggtcgcttc tgatatacca
     1021 aacatctcat atagcatttt caaccgtgct aaaatggtcc ctcgttcacg ggaatcggtc
     1081 atcttatagt atgacatata aagagtataa cgtcgattca tttcaaaaag atgagcatac
     1141 atctcttgga cttcgattga agatagtgcg gctaattcat caaaaaggct taataattct
     1201 ccacgcgttg ctgttgataa tgcgttatct gtaagtaata attgacgaat ctctggtgaa
     1261 aacgtttctg catcaggata atcaattaag cgagaaagaa cggcaaaggt atcctttaaa
     1321 tctgtcaatc gtctaaaatc aatcacgcca aatccctcca tagaaactat cagcataaat
     1381 ctgattagtt gatttgccag cttctgcctt cttaaacata ctcttgtgtt ggggagctaa
     1441 tgcacagcct tcacattcat cataaccaag actaccttgt tcggtttgtg catcttccat
     1501 ttctgccttt tggctacttg gaataacaaa gcggtcttca tatttagcaa ttgccagtaa
     1561 acgataaagt gatgttgccc gttcttctgt taaatcaact cgttccagtt tactgctatc
     1621 aaaatcccga ccactagtct tagcacgcat gtatagccgc atcattgcaa gtttatataa
     1681 ggctttcttg atggcaggaa cgtttccagc agttaataga cttgccaagt attgaacagg
     1741 cacccgcatt tgatcaattc ctgggaagat catttcagga ttctttattg agtcccgtcc
     1801 ttcaaagtaa ctcataactg gcgatagcgg cggaatgtac caaaccattg gcattgtccg
     1861 gtattctggg tgaagtggga aggcaatttt ttcttttact gccattttat agatcggtga
     1921 cttttgtgca gcttcaatca tctcttcaga aatgccatcc ttgagtgctt gcttgacaac
     1981 ttcaggatcg ttgggatcga ggaataagcc aagttgtgct tcatacagct tactctcatc
     2041 aggagttgat gctgcctctt ctactcgatc agcatcgtat agaatggcac caatatatcg
     2101 aattcgaccg acacaggttt cggcacaaac tgttggttga ccttcttcaa ttcgtggata
     2161 acaaaaagta catttttcag ccttatgagt cttccagtta aagtagacct tcttatatgg
     2221 acatccagtc atgcaaaaac gccatcctcg acagcgttct tggtctacta aaacaatccc
     2281 atcttcatct cgtttgtaca ttgcacctga tggacaagag gctacacaag gcgcattcaa
     2341 acagtgctca cataatcggg gaagatacat cataaatgcc tgctcaaagt tatttttgat
     2401 atccccttca attttttgca tgttaggatc ctgttggaca tattcagttg atcctgctaa
     2461 gtcatcatcc cagttaggac cagtggttaa ttccattcct tcgccagtaa tttgcgactt
     2521 aggacgagca acaggttgat gcttttgttc agggccaaat aacgtcttat aatcataggt
     2581 ccatggttcg tagtagttat ctaactctgg catatcatta ttgtaaaaaa tcttgccaag
     2641 agcgatttta tttaatttgc ttccagcacg taattttaat ttaccttttg aattaagggt
     2701 ccaccctcca tggtattgat cttcatcttc ccagcgtttt ggataaccga cacctggctt
     2761 agtttcaaca ttattaaacc acatgtattc agcgcctgga cgatttgtcc atgtattctt
     2821 acaagttact gaacaggtat gacaaccaat acacttatcg aggtttaaga ccatgctgat
     2881 ttgtgcttta atcttcactc cagttcacct tcttcagttt tcttacattt gcataaagat
     2941 cacgttggtt tccagttggt ccataataat tccaaccgta actcaattgg ccatatcctc
     3001 caaccatgtg tgttggctta acatggattt gcgttggtgc attatgtgat cccccacgat
     3061 taccggtaat ggtggaaaga ggttcataaa tttcattatc ttgggcgtgg tacatgtaca
     3121 ttgacccctc aggcatccga acagaaacaa ccgcccgcgc agtaacaacc ccattacggt
     3181 tataaacttc gatccagtcg ttatctttta ctttaatctt attggcatct tggggactaa
     3241 tccaaatagt tggaccgccc cggaacaatg tcagcatttc aaggttgtca tagtacattg
     3301 tatgaatatt ccacttaccg tgaggagtca tgtatttaag cgtaacttca tcttctactg
     3361 gcggaacatc aacatctcct ggagccatta caaccggtgg taaagatggt ttataagttg
     3421 ccatattttc accaaattcc cggaaaattt catgatcaag gtagtaatgt tgacgtcctg
     3481 taagagtaaa tgtaggaaca tttcgttcag tcattaatga aaatggtgtg tagcgagctc
     3541 caccatgttt agcagaagtt ccgattggtg ttggataggc ttcttgtggt tgagcagtga
     3601 tttgcttaaa tgacattgaa tcatcagcat ggccacgacc aatatctgtc aaatgttcac
     3661 cagtccgctc ttgcttcttt tcccaagctc gatcagcgag tttaccattg gaagcagttg
     3721 acatccgtaa gattgcatca catacttttt cgtcttcatc aagtaatgga cagcctgcac
     3781 caatgccttc actagcaatt ccattcattc cttttaaata atcatattga tcatcgactt
     3841 tatagccata gttattcact atattaggtc caagggtaat gaatttatcg taaatcttgg
     3901 tataatcacg agtaaccaat ttcaaggaag gcattgtttt tcctggaatt ggttctgttt
     3961 caccgttctt ccaatcttta atttccccgt atggttgagc gatttcccct tgagtattat
     4021 gtcctagtgg tgcgctctta agatcataga aggttcccgg catgtatttc tttgccattt
     4081 cagaaacggt cttagccaag agcttgaatt gttgccagtc agactttgat tcccacattg
     4141 gactaactgc tgcattaaat gggtgaatga atggatgcat atcagttgat gaaaggtcct
     4201 tcttttcata ccaagtagca gctggtagga caacatcgga gtacattggt gttgaaacca
     4261 ttcggaagtc catatcaaca acaagatcta acttaccaat tgctcccttg tcacgccaaa
     4321 tcatatcctg aggcttaacc cgatcattgg gtttagcaag taatccattt tcagcgccta
     4381 ataaatgttt cataaagtat tcggcacctt tgccagaaga agcaaataag tttgaacgcc
     4441 ataagaagaa cgctttgggt tgattttggt tagcatcagg atcttcagca gcaaaatgta
     4501 aagagccctt cttcaattca tcgacaactt tctttgaaat ttcattaata tcagttgtat
     4561 tgtaatcttt tgcaaaagat aacggattac gatcaaattg tgggtatgat ggtaaccatc
     4621 ctaaacgaat tgccatttga ttataatcag cattatgtaa gtaagagtgt ttactcttcc
     4681 aaacgggtga cttttgagct tgattatcaa tttcttcata acgccattga tcagttgcaa
     4741 agtaatacca agtagtacct tgcatttgac gggcaccacc tttttcccag tcattagcaa
     4801 aagtaatatt tgcccaacct tcttgtggac ggagcttttc ttgaccaacg tagtgagccc
     4861 aaccaccacc agtcatacca acacaaccac acaacatcag catattaata atgtttcgat
     4921 agttcatatc ggcattgaac cagtggttga ccccaccacc catgattacc atactccgac
     4981 cttcattttc ggccgcgttt tgggcaaatt cacgagcaat ttgaataact tgctctgctt
     5041 ttactcccga acggctttcc tgccaagcag gagtaaagta gctctcagca tccattgcat
     5101 ctttagcagc aagttcatca ttaccagtcc gattaattcc catttgagcc atcatcaaat
     5161 cataaacatt agttaccaag tgttctttgc catctgtgaa tttgagcttt ttaactggta
     5221 aatgacgttg cacaacgctg tttccgtcat tactaaatgc tggaaaatca gcaacaattt
     5281 gttcagtttc gccatcttga tcattaatag agagtaccgg atcaatctta ttaccatttt
     5341 ggtctaataa ttcaagattc catttttcct tagcattata ttcttgtccc atcgttccat
     5401 ttggaacaac aatcttgtgg ttattttggt cataaacaac tgtcttccat gctggattga
     5461 ctatcgtatc atcatcaact aagtcactaa tccggacgaa gcgacctggt gtatagtgat
     5521 caccatttgc tgtacttggt tccaattcaa ccatgaatgg taaatcagta aatcgcttgg
     5581 aataatcaat gaaacgttta actgggtgct tttggtagaa ttcatctaaa attacatagg
     5641 tcatggcttg agcaacagca gaatcactac ctggttctgg tgcaagccag tcatcagcaa
     5701 atttcacatt ttcagcataa tcagggctaa ctgccacaat ctttgttcct ttgtacctaa
     5761 cttctgtcat gaagtgtgca tccggcgtcc gtgttaatgg gacgtttgat ccccacataa
     5821 taatgtagga actgttatac cattctgcag attctggaac atcagtttgt tcaccccaaa
     5881 cttggggaga tgcaggtggt agatcagcat accaatcata gaaactcatt tgttccccac
     5941 ccattaaggc aatgaaccgt gctccggcac taaaactcat cattgacatt gcaggaattg
     6001 gggtaaaacc accaatgcgg tcaggcccat acttcttaat tgtgtataag caagcagctg
     6061 aaatcatttc taatgcttca taacgatgaa cacgaattaa gccaccgtgt cctcggacct
     6121 tcttatattt tttagacttt tctggatctt cgacaatact tgcccacgca tctaagggat
     6181 tttcatgttc ttccttggca gcagtccaaa gctcccataa tttgccacga atatatggat
     6241 acttaattcg aacgggactg tattcatacc aagagaaact agctccccga ggacatcccc
     6301 gtggttcata tcctggaata ttaggtccgc atgatggata atctgtggct tgatgttccc
     6361 aagtaataat tccttgcttg acataaacat tccaagaaca tgagcctgta cagttgactc
     6421 catgagttgt tcggacaact ttgtcatgcg cccatcgctg acgataaagt ttttcccaac
     6481 gacgactatt ttcttcaagt tgtgtaaagg ttccattaaa cttatcaacc ttgttaaaga
     6541 accgtgactt catcgttgat tgacctcctt tattgaatgg cttaccaata ttaaaaataa
     6601 agtaagtctt ttccctaatg taaagattag caccataact gctatactac gactagggaa
     6661 atacctatat tttgaactaa atgaggtgct aatatccatg aatcgttacg atcgtcaaga
     6721 aagggtacat caaattggta gtattggtca gcaaaaaatt agccatgcaa ctattatgat
     6781 tgtcggtgta ggggcattgg gaagttatac agccgagcaa cttgtccgtg ctggagttaa
     6841 aagacttgtc ttgattgatc ctgacactgt tgacgtaact aatcttcaac gtcaatcgct
     6901 tttcaccgaa gaagatgcta gcaaacaacg gcttaaggtc gaagcagcta aagaacattt
     6961 acataaaatt aattcagcat gtcaaattac tgcgatccca gcaccgatta ctgctgacct
     7021 tattgatgaa tatcagttta ccctttgttt agactgtctt gataattatc aagcacggga
     7081 cctattaaac aaattagcaa tcatcaaaaa ttttgattat ctgtttgcaa gttgcgcagg
     7141 aacctatgga aatgtgatgg cgatttcgcc gcaaaaacat ccctgcttga attgtctttt
     7201 tcctaatatc aatgaattaa aacaaaacga ttgtgattta attggggtta atactgcttt
     7261 aattccgatt gtagcgggac tacaggtatc tttagcgctt cattatctag ttgataaaac
     7321 acaggttaat tttaatgaat tgatcactgt tgacaattgg tcaatgcaat ttagtaagtt
     7381 tgctattaat aaaaatcacc attgtcctgc ctgtgctaag cctagcagta tttctttaga
     7441 agaagaatca ggaccagaat tacatatgtt atgtggagaa aatgcatatt atacagtcaa
     7501 agagaaacct attaattttg gcagacttaa agaatttttg gctaaaaaag agctcttaat
     7561 taacgcaaat cgattgtttc ttcattttaa atgggaaaat cgtccagtaa gtatattcaa
     7621 gaatggtaag attgttatgt atgacttacc tacttcggcg attgcccaga aacagtttaa
     7681 gtcgttaaat attttgatga aagaagacct attatgaaaa aaatcgcaat tttaacggtt
     7741 agcgatagcc gaacattaga tagcgatact tctggaaaat taattgctat gaagatggct
     7801 aatgcgggcc tatcagtagt tgatcgggta atcgttaatg atgatattgt caatattcaa
     7861 actgcctacc ttcaactaga acaacaagct attgatatca tcattactaa tggtggaaca
     7921 ggaattgctc agcgtgatgt tactattccg gctattcgtc cactcctcaa atgcctaatt
     7981 cctggttttg gggaagcgtt tcgccagata tcttttgatg aaattggtac tcgggccctt
     8041 gcatcacaag ccctagccgg atttaatttc cgcaatcagc ttacctattg tttacctggt
     8101 tcccagaatg cctgtcaaac ggctataaac aaactaattt tgccagaata tgaacattta
     8161 ttatttgaaa gcagttctca acgaaaggaa gttcatcacc atgctcacta gaagaattcc
     8221 aatctctgtt gccgaggcac agaaaaagat taacgaaatt ccccttaaaa cagctacaga
     8281 gacaatcccg ttatcagaag ctaaccaccg tgttttagct aaagatgttc atgccaatta
     8341 tgattatcct cattttcgac gggctggaat ggatggttat gccattttag ccagcgatga
     8401 tcatgacttc cctcgcgaat ttaacgtccg aggagagatt caagctggag caacttggga
     8461 tcaaccatta caatcagggg atgcggtccg aattatgact ggtgcatatg tcccttctga
     8521 tgtaggaaaa gtaattcgaa ttgaaaaaac gcggcccgct aaagatgaaa ataaggttca
     8581 aattattacg actgaaagca agactaacat tacggaagct ggtactgatg taaaaagcgg
     8641 tgatatcgtt ttagcaaaag accaggaaat aaatcccggt ggcctagcag ttttaacggc
     8701 ttttggtgtt caagaagtaa cagtttataa aaaaccacgg attgcaatta tcgccactgg
     8761 aactgaatta ttaggaccta atgccacgat tgaaccggga aagatcttta atagtaatgg
     8821 tattatgcta aaaaatctgg tagaagaaac tggtgggatt gttgattttg aaacccaatt
     8881 accagatgat gctgatctta tcaagcagac tcttgaagaa caaatagcaa ctcatgaaat
     8941 tgtaattact gatggtggtg tttcagttgg tgattttgat tttattggag atgaagcacg
     9001 taaagctgat gaattgcttt ttaataagat taagcaacga ccaggaagcg ttacgactgc
     9061 ctttgttcaa aatagtacgt taataatggc cctttctggg aatccaggag cttgttttac
     9121 tggtttttac ctttatatgg aaccgctgat tcgccgttat caacaccaag ccagccgaat
     9181 taagcaagta cgggcaatat tagcggcccc atataataaa acaaatgggt tcgatcggta
     9241 tcttcgttgt acttatgaat tcaaagataa tcaattttat gtttatccaa atggaatcaa
     9301 cagatctggc tcattagcta acctccagac gacaacctgt ttagcactga ttccgcatag
     9361 tactactcca atgaaggtcg gaacggagac tgacacatgg ctattaccct tcaaataatc
     9421 ggtcataaaa aaagcggcaa gactcttatc actacgactt taatcgaaag gctctcaaaa
     9481 gaagggtatc gagtagctgc tcttaaacat gatgcccata atgccgcaat ggatgtgcca
     9541 actactgaca gtgctagaat gagtagtgct ggagctaaac aggttatttt acaatctgcg
     9601 actgaatttt tccttcatca aaaaagtaat gtgccgtctt taacggaaat ggttgaatta
     9661 ttaagtaccg acaatgattt tgtcttgatt gaaggtcata aggaagccac tcaatatccg
     9721 caaattttat tattaaagcc tggcgaaaat cctaccaatg ttgctcatac tccccctctt
     9781 aaaacaggta gtatttttaa tggaacaacc gctgacttat taggaaaaga tgcaattgta
     9841 aactggtgct atgactactt aaaacaagta aagggggatg cagaatgatt ggattagtat
     9901 atgctggtgg taaatctacc cgttttggga aagataaagc tacttatcat gttccaggat
     9961 taccagctac caatatagag ctagctgtcg agaaattaac acccctttgt cagcagatcg
    10021 ttgtttgtgc taatgaaata aatcgagcgc atatattaaa gttggttggt caagaaccgg
    10081 ctgtgcagat tatctgtgat attccccctt atgatcatca tggtcccctc tcagcaatta
    10141 ttgcttgtac tagtcatttt tcaactctgc aggactattt aactctggct gttgattatc
    10201 cttatctcac aaaagattca cttgctgttc ttgctcgtac gtccaactct tatattgcaa
    10261 caagccagca tagccattat tcattagctc atttttcaat tagcaatgaa caagttacta
    10321 cttgggtcgc tgataatgat gactggcgat tacgtagttt catcattaat aaatgtgtct
    10381 ctcaccccct cgtatatcgc tcaagtgccg aattttcaaa tttaaactat cgtgaggtcg
    10441 atttaaatga aaagtaaaga ttcaatgaca aatcctgatt ttcaaaaact catttccctt
    10501 gtcttaaatg acttaacaat cagacgaaca atgttagaaa atcgggaaca agaagtaaac
    10561 caacaaatga gttcactgga aaaagatgct gaattagagc aattggatga ccaaattcaa
    10621 caaattcaag ctgattttga tcattaccgc gaattccagg atccggaatt tgattttagt
    10681 gcaaccaagt atttccaggg accatcgatg gggttaccac gacatcctta aaaactagat
    10741 ggcagggcta aagaagcaga tcttttgtta gccctgcctt ttaagttgtc tatcgttgct
    10801 tctaaccaaa gaaagcgtta ttatataaaa taggaatatt atgataacaa ttggggaatt
    10861 ttattgggga ggaagcagat cgtgcttgaa acagctaatt ggatacaaaa atattttaat
    10921 caatcaccag atgcaatctt cttatttaaa aatgatgatc ttttagtcag taatgagccg
    10981 gcacaacggt tagttactat gcttaattta gatgtcaatt acctattaca aattggaaag
    11041 aacgcttggt cacaactgga aaatgatgac tgtgcgtcat gtctgattaa aaagcggtta
    11101 aagggagctg cagttccgat aacatttcat tccaatgcta ctcatccctt tcacttttcg
    11161 atggtttacc gtcctcttga tgataaagaa aatgtctttg ccctaactct tgaaaatcgt
    11221 gagcaacagc agcgtctttc tcaggttgaa gagcaccgaa ttcttaatca atacgtcaat
    11281 gaagcgcacg aaaaggaacg gcaaaaaatt tcacaagatc ttcacgatag tgttgcacag
    11341 ggaatctatg cagcaataat gggcattcaa agattagcaa cggtgcaaaa tcaaagaaac
    11401 actgagcagt ttcaatcaat gagtgctgca atcgaaaagc agttacaaac gacccttaaa
    11461 gagattaaag ggctcgcact tgatattcgc ccctcggttc ttgataattt tggcttaatt
    11521 ccagcaatca aagctttagc aaaacgtctt caaaatagta cgggaatcac gattaatgtt
    11581 atagccctta cctctgctga aaaattacaa aaaaacatcc aaaacgttct ttaccgcatt
    11641 acacaagagg caattaataa cgcaattaaa catgctcatt caacagaaat aagtattatt
    11701 gttacggatc acaatagtta ccttcagtta gagattcttg ataatggtat cggatttgat
    11761 gttgatcagc atagtggatt taatgggcat tcacttggat taatgaatat gaatgaacgc
    11821 gttaaggcat ataacggagc ctttacaatt acatcaaaaa ttaataaggg aacgacagtc
    11881 aaggtaaagt ttccctataa taatgcttta aataaggata tggtgagaac aaatgtataa
    11941 cgttttagtt gcagacgacc acgcaattgt tcgctcagga atttcatact tagtcgatct
    12001 tcagccgaat tttacggtag ttgatgggac agcgagtgga actgatacat atattcgagt
    12061 tgaacaaggt ggaattgata tcttaattat ggatctaagt atgccccctg gtgaaaatgg
    12121 tctgattacg actcggcgaa tccatgacaa gtttccaaaa gttaaaatta tcattctctc
    12181 aatgcacgaa gaacaggaat atatcaacaa ggcaatggca aatggcgcaa tgtcttatat
    12241 tttgaagagt tcaccagata gcgaaattgt taatgcccta aaacatgtta taaatggcga
    12301 gaaatatctt gatgcaaata tcattgttag taagacagat attagagaaa taaatgcatc
    12361 tggtaatacc ttaaaactaa agggctacaa tagtctttcg aaaagggaga aagaagtctt
    12421 tccgcttatt gctttaggat attcaaataa agagatctca caaaagatgt ttatttca
//
