LOCUS       c00065_gnlPro..        13585 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KDLPBJCI_65.
ACCESSION   c00065_gnlPro..
VERSION     c00065_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:18:26
            Original ID  :: gnl|Prokka|KDLPBJCI_65
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13585
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..183
                     /locus_tag="ctg65_1"
                     /transl_table=11
                     /translation="TIDNLDNISENTSSAESRIRDTDMAKEMVNYSKNNILAQAGQSML
                     AQANQSNQGVLSLLQ"
     protocluster    1..13585
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1540:3585]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1541..3585
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13585
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13585
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(241..699)
                     /locus_tag="ctg65_2"
                     /transl_table=11
                     /translation="VDRIFEKRLLILLPYHILRYEHFLKHNGTNSKKVKHLLDDFREIN
                     RRLEDASEKEQKSHFYMDMIVLIEKIADYIIPKDNDIRKGLGEIMGGKILKLRSEELLE
                     QGEARGEARGRIDAIQNMIDLGLTKEQILKKYSPEEYEKALNSMPVKA"
     CDS             868..1353
                     /locus_tag="ctg65_3"
                     /transl_table=11
                     /translation="MFKCNRNVVLEHPDNHCPVLRGLAFQMVYMSTNPDNGVRDHGSVL
                     FVMFVSQLFKLFLLAVRSMENFVDQRNEKLRHFLRNGSEYIVENRAVFCCVFCVGIWQR
                     SCQNVSVPHVVSYLSFSIYHKHLLLQYRKYKKQSCYDQFYEIVVLMEIYERNALHEW"
     CDS             complement(1541..3145)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_4"
                     /sec_met_domain="HGD-D (E-value: 2.4e-29, bitscore: 94.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 2.4e-69, bitscore:
                     224.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHANICSYTKAVLEDVMEHDYEGVILTTCCDSIRRLYDTLKSQFP
                     DKFFFLLDIPRKFNDFAVALYERQLKQMLTEYEAFSGKTLDLKRFVSMMQNKAALKKQE
                     NTRMSASAASGKGNGQKLNIGIMGARCNNEIRQLLVDRGANLLFDLTCTGLARDFSITE
                     DQVLHSYAAALLNQIPCMRMLKAANREHFLDGFTDRLDGIIYHTVKFCDSYSYEYADFR
                     QRLDLPILLVETDSTRQCAGQVRTRVEAFMEELKVKKGLSLTGEKQMIKRKGDTVYTLG
                     IDSGSTSTNAVILDENRQIKAFSIVRTGAKSSQSADAALADVLKKAGLDREDISLIVST
                     GYGRVSIPFADKNVTEISCHGKGAHLLFPDVHTILDIGGQDSKAIRLNDNGEVADFVMN
                     DKCAAGTGRFLEMMARSLEISIDELGPVSLQSKENIEISSMCSVFAESEVISLIAQNKE
                     IADIAHGIHKAIAGKAMSLLKRVGLNPGYMMTGGVAKNPGVVAVLEEQLGEKLHIYEEP
                     EIVGALGAALYGLEEIL"
     CDS             complement(3250..3585)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg65_5"
                     /sec_met_domain="HGD-D (E-value: 1.5e-24, bitscore: 78.3,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDELDTTHPLEALATKMLNNLYNGPYEKKANMVVKLAKEMHADGV
                     INFCHWGCKQSAGGVFQLRETLKAADIPLLVLDGDAMDRRNSHDGQIKTRLEAFLEILD
                     KERNSSC"
     CDS             3819..4049
                     /locus_tag="ctg65_6"
                     /transl_table=11
                     /translation="MGNSALPAVLKTLCNKLSTGFRGQVFPTGHPWIDVFRSVLPVSES
                     VLSAAWSHIPRLPENSCPAHRSHKCQDPCAG"
     CDS             4711..5634
                     /locus_tag="ctg65_7"
                     /transl_table=11
                     /translation="MGAQDNTEKVLRSLHVLLSKSEPYPKEPSKVIIDKQQVIDLLAEL
                     NTCIYQIMDEYELTIRSRDKAERDFHKKGDQIIWDASRKAEDIYAASVMYMDETLNRMQ
                     DIMQEADKKVGAIYQEIKEQMEKEEQELRTNKSELKGQLQDLVDTEKYLKIIEERNREI
                     EKEKMEGRPEYEQEKREEKAIYANRQTDIKINQEYLDKLGLSVPEEPVEDLAEEPVEKP
                     VEKPVEKPKKLSPKPEIPAPVTVEDDDEELKQLEEQLRVNLDADYFKWKDEQEEQEAAE
                     EKEKSAGFQNKIKNLIGGHPHDDSGV"
     CDS             5615..6304
                     /gene_functions="resistance (resist) vanR (Score: 272.8;
                     E-value: 1.4e-83)"
                     /gene_kind="resistance"
                     /locus_tag="ctg65_8"
                     /transl_table=11
                     /translation="MTILVCDDDKEIVDAIEIYLIQEGYQVVKAYDGEQALDMLRTKKI
                     DLMVIDVMMPKLDGIRATFQARKTSSIPIIILSAKTEDADKILGLNVGADDYVTKPFNP
                     LELVARVKSQLRRYTTLSSTPSGDAVYEAGGLVINDELKKVTVDGEEVKLTPIEYNILL
                     LLMKNKGKVFSISQIYEEIWNEEAIGADNTVAVHIRHIREKIEINPKEPRYLKVVWGVG
                     YKIEAGA"
     CDS             6353..7693
                     /locus_tag="ctg65_9"
                     /transl_table=11
                     /translation="MHQMFLIMMLCGIYGIGYNLRRHIGGLRILSLFMVIGMVGSFVFL
                     AYLTGVAGRRSEEDATIYLTWIDKIYTDIQMVLFVAFIYLVLFLGRNLHDIQFELSGLM
                     VAVGTVGYLVDVVFLLFYMSIVRRVKNNTLLTYSLIYQAGSFLRRVFISGQNPRLCTRK
                     ARERYEIQHAIEKIAAGALDTTLDVEQFHGQERGIAASVNNIRAGLSEAIQERIRNERM
                     KADLITNVSHDIKTPLTSIVNYVDLLKRENLENENARNYIRVLDEKSQRLKQLTEDLVE
                     ASKISSGNIQLDMQTIDLVELLYQTGGEFNERFEARGLTIVTKLPHNSVMIRADGRQLY
                     RAIENLYTNAAKYALENTRVYVDLEVEENNAVFRIKNISKNPLPEQGAARKDLTERFVR
                     GEESRTTEGSGLGLSIAKNLTQLMGGEFAILVDGDLFAASITFAVVA"
     CDS             7752..10037
                     /locus_tag="ctg65_10"
                     /transl_table=11
                     /translation="MKLYENGAYLVNGRDVVINSPEAASAVNAKTGKTVTPEDAKKQTI
                     AYGILKSHNTSGNMEKLQIKFDKLTSHDITFVGIIQTARASGLEKFPIPYVLTNCHNSL
                     CAVGGTINEDDHMFGLTCAKKYGGIYVPPHQAVIHQFAREMLAGGGKMILGSDSHTRYG
                     ALGTMAIGEGGPELVKQLLNKTYDIDMPGVVGIYLTGTPQKGVGPQDIALAIIGEVFAN
                     GFVKNKVMEFVGPGVSNLSVDYRIGVDVMTTETTCLSSIWRTDDQVKEFYEIHGRTGDF
                     EELNPGEVAYYDSFIELDLSEIKPMIAMPFHPSNTYTIEELNANLMDILDDCEKRAQVS
                     FDGKVDLDLKSKVKNGRLYVDQGIIAGCAGGGFENICDAADILKGSSIGADEFTLSVYP
                     ASTPIYMELVKNGAVANLLETGAIVKTAFCGPCFGAGDTPANNAFSIRHSTRNFPNREG
                     SKVQNGQVASVALMDARSIAATAANKGFLTAATDIDVNYSKPKYFFDKTIYENRVFDSK
                     GVADPDVEIQFGPNIKDWPAMSPLPENLVLKVVSEIHDPVTTTDELIPSGETSSFRSNP
                     LGLAEFALSRKDPEYVGRAKEVQKAQKAVEADTCPGDALPEIHPVMDTIRATFSDVNRS
                     NVGFGSTIFAVKPGDGSAREQAASCQKVLGGWANIANEYATKRYRSNLINWGMIPFVID
                     QGELPFHNLDYLFVPKIREAIADGKTEFEAYVVKDGALKPFTLRMGELTPDEKDIILKG
                     CLINYYRG"
     CDS             10048..11403
                     /locus_tag="ctg65_11"
                     /transl_table=11
                     /translation="MTDVEKQKQMEQIKQSEDGMRQTVLLIKIGLMVFLTFACCTVFFF
                     LVLRYKGVADTWHLITGALQPIIIGLGLAYLLNPVMKFQERHWLPFLKKKMKSEKSAAK
                     VARGLSIAGAILFLLVILVLLIAAIVPSVVSSVTGLVEALPGNVESLIHMVKSGKLGAY
                     GVTDTISDMLTKLTDQVENWATKDLLPQMQQYLLQITSGVITMVKSILNFIIGIIVVVY
                     VLSIKESLVGQSKKIVYAIFKPKHGNIIIEVFHKADEVFGGFIIGKIIDSAIIGVICYF
                     GCLILHIPDTILVAVIIGVTNVIPVFGPFIGAIPTLLLVVIQSPLHALYLLIFIIVLQQ
                     VDGNIIGPKILGDSTGLSAFWVMFSILIGGGLFGFLGMLLGVPVFAMIYYIIRRLVNHS
                     IRKKNLTTVTEAYVEAAGVNEATGAIIYYGEKQKKKRTLKDSGKKDETKKNQ"
ORIGIN
        1 accatcgaca acctggataa catttccgag aatacatctt ctgctgagtc tcgtatccgt
       61 gatacagata tggcaaaaga gatggtaaac tacagcaaga acaacattct tgcacaggct
      121 ggacagtcta tgctcgcaca ggctaatcag tctaaccagg gtgtactttc tctgttacag
      181 taaaagtaaa tatggtcatt acacatcaaa agggattcct tggaatccct tttggtgtgt
      241 ttatgctttc actggcatag aatttaatgc tttttcatat tcttctggag aatatttttt
      301 taaaatttgt tctttggtta aaccaagatc aatcatattt tgaattgcat cgattctgcc
      361 tctggcctct cctctggctt cgccctgttc cagtaattcc tcggaccgta acttcaaaat
      421 cttaccaccc ataatctcac ccaatccttt cctaatatca ttgtcttttg gaataatata
      481 atccgcgatt ttctcaatta aaacaatcat atccatataa aaatgcgact tttgttcttt
      541 ttcggacgcg tcctctaacc ttcggttgat ctcccggaaa tcgtccagca gatgcttcac
      601 ttttttcgaa tttgttccat tatgtttcaa aaaatgctca tatcgtaaga tatgatacgg
      661 aagcagaatc agcagccgtt tttcaaaaat ccgatccacc gtgtatcttt tcgcctgcaa
      721 aaccggaacg cggtaacgta ctttctgacc atctgcaaac gttacgattg cctcatgata
      781 atctggaagc gaacggtgat tgcggatata aagcacgcac gattgaggaa acgcaatctc
      841 ccaaattgca tgttccccca aagaagcatg ttcaagtgca atcgaaatgt cgtactcgaa
      901 catccggata accattgtcc tgtccttaga ggactggcat tccagatggt atatatgtcc
      961 accaatccgg ataatggagt ccgtgatcac ggttccgtac ttttcgtaat gttcgtttcg
     1021 caattgttca aactgttcct cctcgctgta agaagtatgg aaaacttcgt tgatcagcgg
     1081 aatgagaagt tgcggcattt tttgcgcaat ggttcggaat acatcgtcga aaatcgtgct
     1141 gtgttctgtt gtgttttctg tgtcggcatc tggcaacgaa gttgtcaaaa tgtcagtgtt
     1201 ccccatgtag tgtcctacct ttcctttagt atatatcata agcatctgct tttacaatat
     1261 agaaagtata aaaaacagag ctgttatgac cagttctatg aaattgtggt tctaatggaa
     1321 atttatgagc gaaatgctct ccatgagtgg tgattgcggt acaatggcga tgtatcgcat
     1381 aagtaattgt ggtatataat tttataaatc cagtaaaaac agaatatcgt attttcggac
     1441 agaagtcaaa tgatttataa cagtaacaca aaaacaacaa ttgcgatacg attggaaaat
     1501 aaatcgtatc acgattgttg ttgtaaaatt attttctggt ttataggatc tcctcaagcc
     1561 catacaatgc cgcacccagt gcaccgacaa tctccggttc ctcatagata tgcagttttt
     1621 ctccaagctg ctcctccagc acggcaacga cacccggatt cttggcaaca ccgcccgtca
     1681 tcatatatcc cggattcaga ccgacacgtt tcaggaggga cattgctttc ccggcaattg
     1741 ctttgtgaat tccatgtgca atatcagcaa tctctttgtt ctgtgcgatc agggagataa
     1801 cttccgattc agcaaaaaca ctgcacatgc tgctgatttc aatattttct ttggactgca
     1861 gggataccgg gccaagttcg tcgatactga tttccaggga gcgcgccatc atttccagaa
     1921 agcggccggt tccggcggca catttatcat tcatgacaaa atcggcaact tctccattgt
     1981 cattcagccg gatggctttg ctatcctgac cgccgatatc gaggatcgtg tgaacgtccg
     2041 ggaagagaag atgcgcacct tttccgtggc agctgatttc ggttacattt ttgtccgcaa
     2101 atggaatgct gacacgacca taacccgtgg atacaatcag ggaaatatct tcccggtcaa
     2161 gtccggcctt tttcagaacg tctgccaatg cggcatctgc actctgggaa gatttggctc
     2221 cggtgcggac aattgaaaat gctttgatct gtctgttttc gtctaagatt acggcgtttg
     2281 tagaggtaga gccgctgtca attcctaatg tatacacagt atcacccttt ctttttatca
     2341 tttgtttttc cccggtcagg gacaatcctt ttttcacttt caattcttcc ataaaggctt
     2401 ctacacgggt ccggacctgt ccggcacatt gtctggtgga atcggtttct accagcagaa
     2461 tcggcagatc cagccgctgg cggaaatccg catactcgta agaataagag tcacagaatt
     2521 tgacggtatg atatataatt ccatccaggc ggtcggtaaa accgtcaaga aaatgttcac
     2581 ggttcgctgc ttttaacatg cgcatgcatg gaatctggtt tagcagcgcg gcagcatagg
     2641 aatgcaggac ctgatcctct gtaatggaaa aatcacgtgc aagtccggtg catgttaaat
     2701 caaacagcag attggcaccg cggtcgacaa gcagctgacg gatttcattg ttgcatcggg
     2761 cacccatgat tccgatattg agtttctgtc cgtttccttt tccggacgct gcgctggcag
     2821 acatgcgggt gttttcctgt tttttcagag ccgctttgtt ctgcatcatg gaaacaaaac
     2881 gtttcagatc cagtgttttt ccggagaaag cctcgtactc ggtgagcatt tgttttaact
     2941 ggcgctcata gagtgctact gcaaaatcat taaatttgcg gggaatatcc agcaaaaaga
     3001 aaaatttatc cgggaactgg ctttttaatg tgtcatacag acgccggatg ctgtcgcagc
     3061 aggtagtcag aatgacaccc tcatagtcat gttccatcac atcttccagc acggccttgg
     3121 tataggaaca gatgttggcg tgcatcaggg tatccgcatg gttaaaatcc gtaacggatg
     3181 gttccagacg tgtgatttcc gtgtccatgg cttcaaataa ttccatgggg gtatatttac
     3241 atacataacc taacatgatg aattcctctc tttatccaga atttccagaa aagcttccag
     3301 acgggttttg atctgtccgt catggctgtt ccggcggtcc atggcatcgc catccagaac
     3361 gagcagtgga atatccgcgg ccttgagtgt ttcgcgcagc tggaatactc cgccggcaga
     3421 ttgcttacag ccccagtggc agaagttaat gacgccatca gcatgcattt cttttgccag
     3481 ttttacgacc atgtttgctt ttttttcgta tggaccgtta tagagattgt ttagcatttt
     3541 agtggcaagt gcttccagtg ggtgggtggt atccagttcg tccatgtaat ccaggttcat
     3601 ttcggtacac tggatctggt aatctctgtt caggttaaaa tagtgtttga gtgtttcctg
     3661 ataaaaagga agcagatgta cccacacaat ccgggtgccg tcatatttcg gatattgttt
     3721 gatatcctcg gcaaaactgc ggaacaggtc aagggtttcc ggtgttccga tgtttaagtg
     3781 ggtggcaaaa agcatgtaca tctgcagagt cagtgtcgat gggtaatagc gctctgcctg
     3841 cagttttaaa aactctttgt aataagcttt cgactggttt tcgcgggcaa gtgtttccga
     3901 caggtcatcc atggatagac gttttccggt cagtgcttcc agtttctgaa tcagttcttt
     3961 cagctgcatg gtcacatatt ccacggcttc cggagaacag ctgtccggca catcgatcac
     4021 ataagtgtca agatccgtgt gccggctgac atagcggaat gtgttaatat tgccgtcaca
     4081 aatcatggaa gttgtcacac cgagtctggc aggtgaaata attccggagt ctacggcacc
     4141 gataaaatct ttgtgatagg aacagagcgt ggaggcaatt ccccggcttt ctgcgcggtc
     4201 gataaaatag tcttcacacg taaatcctga gagaaacgag gaaagacatt ccatggaaag
     4261 cgcactgagt ccgaagcact ggaaaatttc cacgggtgca aacagattgc accagaccgt
     4321 ggattccggg tattccagcg catgaagcgt attttttacg ccgagcgtat tcagcttctg
     4381 atatgctttc ggcattgttt tttctgcaaa atgttcagtc cggaactgtt cgagatgtaa
     4441 tccgatgtca atcattttgc gggaaactgc cgggtgggtg ccggcatatt ttttaatata
     4501 atttccgtaa gttttgacga tattcatagt atatatcctt tattaaacag gttcattttc
     4561 aaaaaattat tataaccttg tgtctgtaaa aaataaagtt ttgtgtaata aaatttagaa
     4621 aaacctaaga atctaaaata ttgcgtatta tagggggatt gattataata gaaagtacgg
     4681 aattatctat tatggaagga atcaggacac atgggagcac aggacaatac ggaaaaggta
     4741 ctgcgcagtc ttcacgtttt gctgtcgaag agtgagccgt atccgaaaga gccgagtaaa
     4801 gttatcatag ataagcagca ggtgattgat ctgctggcag aattaaatac ctgtatttat
     4861 cagattatgg atgaatacga gctgaccatt cgaagccgtg acaaggcaga gcgcgatttc
     4921 cataaaaagg gagatcagat catctgggat gcaagccgta aggcagagga catttatgcg
     4981 gcatctgtca tgtatatgga tgaaacgtta aaccgtatgc aggatatcat gcaggaggca
     5041 gacaaaaagg tcggtgccat ctatcaggaa attaaagaac agatggaaaa agaagaacag
     5101 gaattaagaa ccaacaaatc cgaactcaaa ggacagctgc aggatctggt tgataccgaa
     5161 aagtacttaa agatcatcga ggaacggaac cgcgagattg agaaggaaaa gatggaagga
     5221 agaccggagt acgagcagga gaagcgggaa gaaaaagcaa tttacgcaaa ccggcagacc
     5281 gatattaaga ttaaccagga atatctggat aagctgggac tttccgtacc ggaagaaccg
     5341 gtagaagacc ttgcggaaga accagtagaa aagccagtgg aaaagccggt ggaaaaacca
     5401 aagaagctgt cgccgaagcc ggagattccg gcaccggtta cggtagaaga tgacgatgaa
     5461 gagttaaagc agctggaaga acaactgcgt gtgaatctgg atgctgatta ttttaagtgg
     5521 aaagatgaac aggaagaaca ggaagcagca gaagaaaaag aaaaatccgc cggctttcag
     5581 aacaagatca agaacctgat aggaggacat ccgcatgacg attctggtgt gtgatgatga
     5641 caaggaaatt gtagacgcaa ttgagattta cctgattcag gaaggatacc aggtagtaaa
     5701 agcatatgac ggggaacagg ctctggatat gcttcgcaca aagaaaattg atctgatggt
     5761 gatcgatgtg atgatgccga aactggatgg aatccgtgcg acattccagg cacgtaaaac
     5821 aagcagcatt cccattatca tcctgtctgc caagacagaa gatgcggata agattctggg
     5881 gctgaacgtg ggggcggacg attatgtgac caagccgttt aatccgctgg aactggttgc
     5941 ccgtgtgaag tcacagctgc ggcgttatac cacactttcg agcacccctt ccggtgatgc
     6001 cgtttatgaa gccggcggcc tggttattaa cgatgaatta aaaaaagtta cggtagatgg
     6061 ggaagaggtc aaactgactc cgatcgaata caacatcctt ctgcttttaa tgaaaaataa
     6121 aggaaaagta ttttccatca gtcagattta tgaggaaatc tggaatgaag aagcaattgg
     6181 cgctgacaat acagttgctg tccacatccg gcatatccgg gaaaaaatcg aaatcaatcc
     6241 gaaagaaccg cggtatctga aagtggtctg gggtgtcggc tataaaatcg aagcgggggc
     6301 gtagctgtct atgaaagaat tctccagcgg aaaaaagggc gcagccattg tcatgcatca
     6361 gatgttcctg attatgatgc tttgcggaat ctatgggatc ggatacaatc tgcgcagaca
     6421 tatcggaggg ctgaggattc tcagcctgtt tatggtgatc ggcatggtcg gaagctttgt
     6481 atttcttgcc tatctgacag gtgttgcagg gcgccggtcg gaggaggatg caaccattta
     6541 cctgacctgg atcgataaaa tttatacgga tatccagatg gtgctttttg tggcattcat
     6601 ttatcttgtg ctctttttgg ggagaaatct ccatgacatc cagtttgaac tgtccggact
     6661 gatggtagcg gtcggaacag tcgggtatct ggtcgatgtt gtattcctgc tgttttatat
     6721 gagcattgtc cggcgggtca aaaacaatac ccttctgaca tacagtctga tctatcaggc
     6781 aggaagcttc ctgagacggg tgtttatctc cggacagaat cccagactgt gtacgcgtaa
     6841 ggcgcgcgaa agatatgaga tccagcatgc aattgaaaaa attgcggcag gggcactgga
     6901 tacgacactg gatgtggaac agtttcacgg acaggaaaga ggcattgcag cttctgtgaa
     6961 taatatccgt gcagggctga gcgaagccat tcaggagcgg atccggaatg aacggatgaa
     7021 ggcagacctg atcacgaatg tttcccatga tatcaaaaca ccgcttactt ccattgtcaa
     7081 ttatgtggat ctgctcaaac gtgaaaacct ggaaaacgaa aatgcacgta attatatccg
     7141 ggttctggat gaaaaatccc agcggctgaa acagctgacg gaggatctgg tcgaagcatc
     7201 aaagatcagt tccggaaata tccagctgga tatgcagacc atcgatctgg tagaactact
     7261 gtaccagacg gggggtgagt tcaatgaacg ttttgaggca cgggggctga ccattgtgac
     7321 gaaactgccg cacaattcgg tgatgatccg ggcagacgga cggcagctct accgtgcaat
     7381 tgaaaatctg tataccaatg cggcaaaata tgcactcgaa aataccaggg tttatgtaga
     7441 tctggaagta gaggagaaca atgcggtttt ccgtatcaaa aatatttcga aaaatccgct
     7501 gccggaacag ggagcggcga ggaaagacct gacggagcgt tttgtgaggg gagaggaatc
     7561 ccgcacgaca gagggaagcg gtcttggact gtccattgca aagaatctta cacagttgat
     7621 gggcggtgag tttgcaatcc tggtagatgg cgatctgttt gcggcatcca ttacgtttgc
     7681 agtcgttgca taaaaataca ttttattata taattatcat taaccatgat ttcgaaaaca
     7741 aggaggaaac tatgaagtta tacgagaacg gcgcatacct ggtcaacggc agggatgttg
     7801 tcattaattc accggaagcg gcatctgctg tcaatgcaaa gacaggaaag actgttacac
     7861 cggaagatgc aaagaaacaa accattgcat acggaatttt aaagagtcac aatacatccg
     7921 gcaacatgga aaaactgcag atcaaatttg ataagctgac ttcccatgat attacatttg
     7981 tcggcatcat ccagaccgcc agggcatcag gtcttgagaa gttcccgatt ccttatgtac
     8041 tcaccaactg tcacaacagt ctgtgtgcag tcggtggaac catcaacgaa gatgaccata
     8101 tgtttggact gacatgtgca aagaaatacg gtggaatcta tgttcctcct catcaggcag
     8161 ttattcacca gttcgcaaga gaaatgcttg caggcggcgg aaagatgatc cttggatcag
     8221 actcccatac ccgttacgga gcactgggaa ccatggcaat tggagaaggt ggtccggagc
     8281 ttgtaaagca gcttttgaat aagacttacg atattgatat gccgggagtt gtcggcattt
     8341 acctgacagg taccccgcag aagggtgtcg gtccgcagga tatcgcactt gccattatcg
     8401 gtgaagtatt tgccaacgga tttgtaaaga ataaagtgat ggagtttgtc ggaccgggcg
     8461 tgtccaatct gagtgttgat taccgtatcg gtgtcgatgt tatgacaaca gaaacaacct
     8521 gtctgtcttc catctggaga accgatgacc aggtgaagga attctatgag attcacggaa
     8581 gaaccggaga tttcgaggaa ctgaatccgg gagaagttgc atactatgac agttttatcg
     8641 aacttgattt aagcgagatt aagccaatga tcgccatgcc gttccatcca agcaatacat
     8701 acacgatcga ggaattaaat gcaaacctga tggatattct cgatgactgt gagaagcgtg
     8761 cacaggtaag ttttgatgga aaagtagacc ttgacttaaa gagcaaagta aagaacggaa
     8821 gactgtatgt agatcagggt atcattgccg gatgtgctgg tggtggattt gaaaatatct
     8881 gtgatgcagc agacatctta aagggttctt ccattggagc ggacgagttt acgctgagtg
     8941 tttacccggc ttccactccg atttatatgg aactggttaa gaacggtgcc gttgccaatc
     9001 tgttagagac aggtgctatt gtcaagactg cattctgcgg accatgcttt ggtgccggag
     9061 atacgcctgc gaacaatgca ttttctatcc gtcattctac acgtaacttc ccgaaccgtg
     9121 agggctctaa ggtacagaac ggacaggttg cttccgtagc actgatggat gcgcgttcta
     9181 tcgctgcaac cgctgcaaat aagggattcc ttaccgcagc taccgatatt gatgtaaact
     9241 acagcaagcc gaaatacttc tttgataaga ccatttatga aaatcgtgta tttgacagca
     9301 agggtgtggc agatccggac gtagagattc agtttggacc aaatatcaag gactggccgg
     9361 ctatgagccc gcttccagag aatcttgtgc tgaaagttgt ttccgagatt cacgatccgg
     9421 tgaccacaac ggacgagctg attccttccg gagagacatc ctctttccgt tccaacccac
     9481 tgggactggc agagtttgca ctttccagaa aggatccgga atatgttgga cgtgccaagg
     9541 aagtacagaa ggcacagaag gctgtcgaag cagatacctg tccgggggat gcacttccgg
     9601 agattcatcc ggttatggat accatccgtg caacgttctc cgatgtcaac cgctcaaacg
     9661 ttggttttgg aagtacgatt tttgcagtaa aaccgggaga cggttctgcg cgtgagcagg
     9721 cggcttcctg ccagaaggta cttggcggat gggcaaacat tgcaaatgaa tatgcgacca
     9781 agagataccg ttccaacctg attaactggg gtatgatccc gtttgttatt gatcagggag
     9841 agcttccgtt ccacaatctg gattacctgt ttgttccaaa gatccgtgag gcgatcgcag
     9901 acggaaaaac agaatttgag gcatatgtgg taaaggatgg tgctttaaag ccatttaccc
     9961 tgcgtatggg agaactgaca ccagatgaga aagatattat tctcaaaggc tgcctgatca
    10021 attattaccg cggataggag atcttgtatg acagacgtgg aaaaacaaaa acagatggaa
    10081 cagatcaaac agagcgagga tggcatgcgt cagacggttc ttctgattaa aatcggattg
    10141 atggtatttc tcacctttgc ctgttgtacc gtatttttct tcctggtgct ccggtacaag
    10201 ggggttgcag atacctggca tctgattaca ggtgcattgc agccgattat tatcggactg
    10261 ggacttgctt atctgcttaa cccggttatg aaatttcagg agcggcactg gctgccgttt
    10321 ctgaaaaaga aaatgaaatc agaaaaatca gcggctaaag tggcacgtgg attgtccatt
    10381 gccggggcaa tcctgtttct tctggtgatt ctggtacttt tgattgcggc aattgttcct
    10441 tcggtggtat caagtgttac cgggctggtg gaagcactgc ctggtaatgt ggagagcctg
    10501 atccatatgg tgaaaagtgg aaaactcgga gcctatggag tgacagatac catcagtgat
    10561 atgctgacaa aactgacgga tcaggtggaa aactgggcaa cgaaggatct gctgccacag
    10621 atgcagcaat atctgctgca gattacttcc ggcgtaatca cgatggtcaa atccatatta
    10681 aacttcatca ttgggatcat tgtcgttgtt tatgtcttat ccattaaaga aagcctggtg
    10741 ggacagagca aaaagattgt gtatgcgatc tttaaaccga aacatggaaa cattattatc
    10801 gaagttttcc acaaggcaga tgaagtattt ggtggtttca tcattggaaa gattatagat
    10861 tctgccatca tcggagtaat ctgttatttt ggatgtctga tcctgcatat cccagatacg
    10921 atactggttg cggttatcat tggtgtgacg aatgtcattc cggtgtttgg accgtttatc
    10981 ggtgcgattc cgacacttct tctggtggtg atccagagtc cgctgcatgc gttgtatctg
    11041 ctgatattta ttatcgttct gcagcaggtg gatggaaata ttatcggacc gaagatttta
    11101 ggtgattcca ccggattatc cgcgttctgg gtaatgtttt cgatcctgat cggaggcgga
    11161 ctgtttggat ttctgggaat gctgcttggg gttccggtgt ttgcaatgat ttactatatc
    11221 atccgcagac tggtaaacca cagcatacgg aagaaaaacc ttacaaccgt aacggaggca
    11281 tatgtggagg cggccggtgt gaatgaggca accggtgcga tcatatatta cggggaaaaa
    11341 caaaagaaaa agagaacttt aaaagattcc ggaaagaaag acgaaacaaa gaaaaaccag
    11401 taatttcaag ggctgtacgc gtttgtgtgc agctcttttt ttcggattat tttttgacac
    11461 taattgccgc ctatggtata cttgaaaata gacagataga cctgtttggg gatattttaa
    11521 ggagataaca attggacaaa tacgaatata atctgaagct tgatcagatg aaatcccatt
    11581 atgcggaaga gaaatacgat gaggcagcag atattgcaga tactatcaat tggaataagg
    11641 ttaaaaatgt aaatggtctg gtaaaagctg gggaagtgta cgaaaaagta cagcgttatg
    11701 aggagagccg ggaagttttg ctgatggcat atgaccgctc gccgatcgga agaatgatta
    11761 tttaccgtct tgcggaagtg gcggtcaaga tgaaagattt tcaggcggca caggattatt
    11821 atgatgagtt tgtggagatt gcgcctcatg acacccttaa atatgtactt cgctatgata
    11881 tacagaaggc acagggggct tcttatgaag aactgatacc gattcttgaa gaactcaagg
    11941 agcaggaata tacggaagag tgggcatatg agcttgctta tctgtatcac aaagcaggga
    12001 tgagtgagaa gtgtattgat gcatgtgatg agctggttct ctggtttgga gacgggccat
    12061 atgtagagcg tgcattggaa ctgaaaatgc tgtatcagcc attgacgaaa acacaggaag
    12121 aaaagtatcg gtcgttttgt caggcaaaag atgacagagc aggtttgaca cacattgatg
    12181 tggaggagat ggcgcgtgcc ggggagaccg tgcatgatcc ggtcgcaatt ccaaaagtag
    12241 aagtaaacac agaacggttt aataccgtca atcttcaggc ggaaattgca aagggtatgc
    12301 agcagatcat ggatgcaacc gaaaaagaga cggtcacgga tacgctggac aatatcaatc
    12361 gtatggtgga agatgtccct tatctgaaaa tgcagatgga ggaagaaaag cctgaggcac
    12421 agccggaaca gaatacacgg cacattgaga cagatgagga gattgatggt tcactcaaga
    12481 caaatttcaa agagttgttg ggagaagact ccgatggtca gatgagcatg atgacaaatg
    12541 agaaaaacat gattgagcat cagatcacag gccagatgac aattgaggaa gtgctgagtg
    12601 agtgggagaa aatgcgcaag gctgcggaag ctgcactgga agatgccaga aagcggaaac
    12661 tcgaatccgc caaagcgcgt gcactgcagg aggcaggcga tattatggac cgcctgacag
    12721 gagtattgcc aaaactggat gcggtactgg cagagaaggc ggatattgtg gaggaaacga
    12781 cggaaacacc gccacagacg ccggaaaggg aaacaccgcc ggcaacgaat gagccggaag
    12841 aacgaaagga agaagaggaa gagaacaaaa aagaggaaca gcctgccagg gatacagatg
    12901 ccgaagaact ttggccagag ggagtatctt tagaagaaat ggtacgttcc cagcagaaaa
    12961 agaagactga agctgccgca cagaaaccgg cagaagagac atccgatgtg acagaagatg
    13021 acaaaaactt aaatgagaat cgtggtgtag aagaaatgga aacaaagaca gaatcagata
    13081 caacaaagaa aaaggatttt gaggaggttc cgatcgagga tctgccacag aaaccaacac
    13141 ttgcacagga gagggaagaa gagtttgctt ttgtaagaag aaaaacagat cgctcttcct
    13201 ggaaaggaaa aacagtacat attccacagg tagacacacc ggtggatctg ggaaaagagg
    13261 aaaaacagaa tatcccgctt gtagaactga ccgatgaaca gaaagcgatt ttttcgtatt
    13321 ttatgccggt gaagggcatg gaggatcagc tctgcaaagc gttgacagtt gcttcgtccc
    13381 atctgaaaaa taaggaaact gcatcgaggg ggaatctcgt aattaaaggc ggacagggaa
    13441 gtggaaaaac aacacttgcc accagcatga tcaaagtcct gcagcaggag accggggttt
    13501 tggatggaaa gattggaaag atccatgcgg aagcattgaa ccagaaaaat gtcggcgggc
    13561 tgctggataa ggtggcagga ggatg
//
