LOCUS       c00052_gnlPro..        13336 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDKPAMKK_52.
ACCESSION   c00052_gnlPro..
VERSION     c00052_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:14:18
            Original ID  :: gnl|Prokka|GDKPAMKK_52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13336
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13336
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2623:12439]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_eut-pdu-related"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2624..12439
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_eut-pdu-related"
                     /protocluster_number="1"
     cand_cluster    1..13336
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="GR_eut-pdu-related"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13336
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="GR_eut-pdu-related"
                     /region_number="1"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..659)
                     /locus_tag="ctg52_1"
                     /transl_table=11
                     /translation="MLALERRNLILEKLQAEKRVVVSELSQLYDVSEETIRRDLDKLEK
                     EGLAIKSYGGAVINEDVSIDLPFNVRKNQNVTGKQKMAELAASLVKDGDHIFLDASTTA
                     VFVAKALKEKERLTVITNSMEILLELADVSGWNIISTGGVMKEGYLAFLGSKTDESIRS
                     YYVDKVIFSCKALDLEWGIMESQEAFGSTKRAMIGSGRKKILVVDSSKFDQTAFSV"
     CDS             complement(726..1274)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 69.1; E-value:
                     8.4e-22)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg52_2"
                     /sec_met_domain="BMC (E-value: 2.1e-26, bitscore: 81.9,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKAIGMIEFKTTSTGVTAADAMVKTSEVEIVEAQTVCPGKYIAI
                     ITGDLSAVKAAVDTAVTTYEDKCIDSFVLGNPHESIFPAIYGTTQVEDISALGILETYD
                     AASIIEAADQAAKTAIVDLIELRIAKGMCGKSYMMITGEVSAVEASIDRAKELVAAKGM
                     YLDSSVIAHPDRRMIDSIL"
     CDS             complement(1291..2619)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RnfC_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_3"
                     /sec_met_domain="Fer4_17 (E-value: 4.2e-12, bitscore: 36.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 5.9e-09, bitscore: 25.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 8.6e-43, bitscore:
                     136.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.8e-20, bitscore: 62.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKELQDIIQQNGVVGAGGAGFPTYMKLTDKANTILMNCAECEP
                     LLKLHRQLLEKHAYEIMKTFHMIQETVGASEAIIGIKKSYVQTIHALNQHIEEFPGMRL
                     HLLDEVYPMGDEVVLIYEATGRVVRPGGLPIEQGVAVFNVETVYNVYRAVEEKQPVTDK
                     YVSVVAEVSDPVTVRVPLGCTLEEVVAQAGSTTVKDPVYFVGGPMMGRIGNGSDPVTKT
                     TNAILVLPKDHLIVAKKQRTSSIDLKRAASICCQCNTCTDLCPRHNLGHPIDPAKFMRA
                     ASNNDFRDLNPYIDASFCSSCGVCEMYSCPQSLAPRSLLADMKGGLRKAGIRPPQGVQP
                     KPVQESREYRKVPEERLMARLGLTRYDKDAPLKEELVQVKKVRILLSQHIGAPAQAVVK
                     AGDEVIRGQMIAQPAQGLSVGIHASVSGKVTEVTDRYIIIAVK"
     CDS             complement(2624..2890)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: EutN_CcmL"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_4"
                     /sec_met_domain="EutN_CcmL (E-value: 5.8e-32, bitscore:
                     100.4, seeds: 194, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVGKVVGSVVSTRKSEKLIGSKFMIIEPVHHMKGDLSQLVAIDM
                     IGAGVGEYVLVAQGSAARIGCGVETAPVDAAIVGIIDDGAGLE"
     CDS             complement(3023..3667)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: PTAC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_5"
                     /sec_met_domain="PTAC (E-value: 9.1e-30, bitscore: 92.9,
                     seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LESNNIELITRMVIQAINQNEKKGDGFMVPIGVSARHIHLTQEHV
                     EALFGPGYQLTKKKELMGGQFASNETVTIVGLKLRAIENVRILGPVRKASQVEVSATDA
                     IKLGMNVPVRESGDVAGSAPIAIVGPKGAVYLKEGCIVAMRHIHMSPKDAQAAGVKDGD
                     IVSVKADNERGTIFNQVKIRVDDSFTLEMHIDTDEANAAKIATGTTVTIIK"
     CDS             complement(3753..4229)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.4; E-value:
                     1.4e-31)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg52_6"
                     /sec_met_domain="BMC (E-value: 3.5e-32, bitscore: 100.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEKKPEADKNAPKKAAAPRRTKAKTSSKPEVKAQTADTAAETA
                     NKTESQKEQIKETVSHKEEKVMTQEALGMVETRGLTAAIEAADQMCKAANVALVGTEKI
                     GSGLVTVMVRGDVGAVKSAVESGSAAASRLGELVATHVIPRPHTDVEKILPVLK"
     CDS             complement(4229..4531)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 78.4; E-value:
                     1e-24)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg52_7"
                     /sec_met_domain="BMC (E-value: 2.6e-25, bitscore: 78.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKSYGFIEITGVVAAIDALDIMCKTADVELASWERKLGGRLVTI
                     IVEGDVSAVTEAVNAAATGAIKKPVSYAVIARPHEEIVRMVELSASRWKNNQGDE"
     CDS             complement(4568..4843)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.7; E-value:
                     1.1e-31)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg52_8"
                     /sec_met_domain="BMC (E-value: 2.8e-32, bitscore: 100.7,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQEALGMVETRGLTAAIEAADAMTKAAEVALVGTEKIGSGLVTV
                     MVRGDVGAVKAAVESGSAAASRLGELVATHVIPRPHTDVEKILPSI"
     CDS             complement(4916..5230)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 75.8; E-value:
                     6.6e-24)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg52_9"
                     /sec_met_domain="BMC (E-value: 1.7e-24, bitscore: 75.8,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAVGILEVFGLATAFVAGDAGCKAANVRLEVFDKNKPANADSL
                     PVPLLVCIKFRGSVTDVTAAVEAGMEVANRMTGVVQHYVIPNPEEGTEKMLKISALDKD
                     "
     CDS             complement(5326..6543)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_10"
                     /sec_met_domain="ADH_N (E-value: 1.3e-17, bitscore: 53.8,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 4.1e-23, bitscore:
                     71.9, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMNNVNIEEIVKQVLSGMTGNAPAAASAPAASTGIPKTARVAVL
                     TEKEHFDIKEYPIPPIGDDDILVKVEGCGVCGTDAHEFKRDPFNLIPVALGHEGTGEIV
                     AMGKNVKVDTAGKPVKVGDKVVTCMIFKDDPDITMFDLNKKNVGGADVYGLLPDDDVHL
                     NGWFSDYIFLRGGNFGTTFFNVSDLDLDSRILIEPCAVLVHAVERAKTTGILRFNSRVV
                     VQGCGPIGLICIAVLRTMGVEHICAVDGNEKRLEFAKRMGADTSVNFMNFKGIEALTEA
                     VKEAQGGHLADFAFQCTGNPKAHANIYKFIRNGGGLCELGFFINGGDATINPHFDLCSK
                     EINLVGSWVYTLRDYVTTFDFLKRAKAIGLPMSELITDKFPLEQINEALQTNLAMTGLK
                     IAVVNK"
     CDS             complement(6569..7957)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: Aldedh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_11"
                     /sec_met_domain="Aldedh (E-value: 3.6e-37, bitscore: 117.9,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPINENMVQEIVQEVMAKMQIADAPTGKHGIFKEMNDAIEAAKKS
                     QLIVKKMSMDQREKIITCIRKKIKENAEVMARMGVEETGMGNVGDKILKHHLVADKTPG
                     TEVITTTAWSGDRGLTLIEMGPFGVIGAITPCTNPSETILCNTMGMLAGGNTVVFNPHP
                     AAIKTSIYAINLLNEASLECGGPDNIAVTVEKPTLETSNVMMKHKDIPLIAATGGPGVV
                     TAVLSSGKRGIGAGAGNPPALVDETADVRKAATDIVNGCTFDNNLPCIAEKEIVAVSSI
                     VDELMHYLVTENDCYLASKEEQDKLTEVVLAGGKLNRKCVGRDARTLLSMIGVNVPANI
                     RCIVFEGPKEHPLITTELMMPILGVVRARDFDDAVEQAVWLEHGNRHSAHIHSKNIDNI
                     TKYAKAIDTAILVKNAPSYAALGFGGEGYCTFTIASRTGEGLTCASTFTKRRRCVMADS
                     LCIR"
     CDS             complement(7994..8863)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_12"
                     /sec_met_domain="Aldolase_II (E-value: 6.7e-47, bitscore:
                     149.9, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNEYEIKKQICDIGRRIYSRNMVAANDGNISVKLNDNEFLCTPT
                     GVSKGFMTPEYICKVDREGNVIQANPGFKPSSEIKMHMRVYEKRPDVGSVVHAHPIYAT
                     SFAIAGIPLTQPIMPEAVISLGCVPIAEYGTPSTMEIPDNLEKYLPYFDAVLLENHGAL
                     TWSTDLNAAYMKMESVEFYAQLLYQSKVLGGPKEFDEKNIKKLYEIRRKFGMAGKHPAN
                     LCLNKDGHNCHNCGGACHDGEFKKFPGYQYDFVGGGDSQPAAGTADKSEAELVAEITKQ
                     VMAQLGMK"
     CDS             complement(9049..9840)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_13"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-28, bitscore:
                     89.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLDTKGRVFDVQKYSIHDGPGIRTIVFLKGCVLRCKWCCNPES
                     QEYKIQTMKVQGEDKVIGRDVTVREMIEEVEKDRVYYYRSGGGMTLSGGECLCQPEFAG
                     ALLRAAKERGISTAIESMACAKWETIETILPYLDTYLMDIKHTNPAKHKEFTGRSNELM
                     MENARKVALSGKTRLVIRVPVIPTFNDTVEEIQGIARFADTLPGVDKIHLLPYHRLGQD
                     KYEGLGRPYLMGNVEPPSKEHMETLKKAVHAVCGLDCQIGG"
     CDS             complement(9914..12439)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: PFL-like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_14"
                     /sec_met_domain="Gly_radical (E-value: 3.5e-36, bitscore:
                     114.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL-like (E-value: 7.3e-264, bitscore:
                     867.3, seeds: 123, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKFQTSDIPKSPRIQKLVDALYEHMPVIESARAKLITESYKETE
                     GEPIITRRAKAFAHILHNIPIIIRDNELIVGSSTIAPRGCQTFPEFSYEWLEAELDTVA
                     TRTADPFEIAEETKAELKEADKYWKGKTTSELATSYMAPEAIKAIEHNIFTPGNYFYNG
                     VGHVTVKYWEVLETGFEGIMEKAQKELDGCSVGDGNYARKSHFLEAVILSCKAVIDYAG
                     RYAKLAQEMAAQTSDPVRKQELFVIAENCSRVPAKGAQNFYEACQSFWFVQQLLQMESS
                     GHSISPGRFDQYMYPYYKKDMEAGTITREFAQELMDCIWVKLNDLNKCRDAASAEGFAG
                     YSLFQNLIAGGQNKEGEDVTNDLSVMCIQASMHVHLPAPSLSVRVWNGSPHEFLIKAAE
                     LTRTGIGLPAYYNDEVIIPALQNRGLSLEDAREYNIIGCVEPQKAGKTEGWHDAAFFNM
                     CRPLELVFSNGMDKGEMVGIPTGDVTQMKTFDEFFDAYKKQMEYCISLLVNADNAIDVA
                     HAERCPLPFLSCMIDDCLKEGKSVQEGGAVYNFTGPQGFGIANMADGLFAIRKLVYEDK
                     KVSMKELKEALAWNYDKGLDAQSAGDMTEMIMKAMQKAGRNVDASTAEGLLKTFMGMKP
                     GEQKTQRFKEIHDMIDEVPKFGNDIPEVDYFAREVAYTYSKPLQRYNNPRGGKFQAGLY
                     PVSANVPLGGQTGATPDGRYAHTPVADGVSPSAGKDVKGPTAAATSVSRLDHFIVSNGT
                     LFNQKFHPSALSGREGLEKFVALIRGYFDQKGMHMQFNVVDRQTLLDAQEHPEKYKHLV
                     VRVAGYSALFTTLSRSLQDDIIRRTEQGF"
     CDS             complement(12565..12696)
                     /locus_tag="ctg52_15"
                     /transl_table=11
                     /translation="MLLLTCLKKNEMSIIKTKQKQPEQKKKQIKNNIKVQDVHVDLC"
     CDS             complement(12823..13206)
                     /locus_tag="ctg52_16"
                     /transl_table=11
                     /translation="MKITEELLNEMKIKDENFSDGLIKPDGDYVRIPRGHLHGMMELLP
                     WTENEIWKMIPDDDSPLFWLIEKTGCVLTDYNNSIGMKMTPAQQTVFDMMRKHGVLTDD
                     YYDLTKQREKVREAREQKENRKQ"
ORIGIN
        1 gctacggaaa acgctgtctg atcaaattta gaactgtcaa caaccagaat tttctttcgt
       61 ccggaaccga tcatcgctct cttggtagag ccaaaagctt cctgagattc cataatcccc
      121 cattccagat ccagtgcctt acacgaaaag ataaccttat ctacataata agaacgtatg
      181 gattcgtctg tctttgatcc gagaaaagcc agatatcctt ctttcattac gcctccggtg
      241 gagataatgt tccacccgga tacatcagct aactccagaa gtatttccat ggaattggta
      301 attacggtaa gacgttcttt ttcctttaat gctttcgcca caaaaactgc cgtagtactc
      361 gcatccagga aaatatgatc tccgtctttc acaagggaag ctgcaagttc agccattttc
      421 tgctttcctg taacattctg gttcttacgt acattgaaag gcaaatcaat gcttacatcc
      481 tcattgatca cagcaccgcc ataacttttt atcgcaagtc cttccttttc aagtttatcc
      541 agatcacggc gtatggtctc ttcagagacg tcataaagct ggctcagctc gctgaccacc
      601 acccgctttt ctgcctgtaa tttttcgaga atcagatttc ttctctccag tgcaagcata
      661 tctttgcccc cttttttgag aaatttttta tgagtgtcag ggtcagaaac ttcttacccc
      721 ggatattata aaatactgtc gatcattctt ctgtcaggat gtgcgataac ggaagaatcc
      781 aggtacatac ccttggcagc tacaagttct tttgccctgt caatggaagc ctctaccgca
      841 gaaacttcac cggtgatcat catatatgat tttccgcaca tacctttggc aatacgaagt
      901 tctatcagat ctacgatcgc agtcttagct gcctggtctg ctgcttcgat aatggaagct
      961 gcatcataag tttcaagaat tcccagcgca ctgatatctt ctacctgagt agttccgtaa
     1021 attgccggga aaatggattc atgcggattg cccagcacaa agctgtcaat gcatttatcc
     1081 tcatatgtag ttactgccgt atcaacggcg gcctttaccg cacttaagtc accggtaata
     1141 attgcaatat atttaccagg acatacggtc tgtgcctcga cgatctctac ctcagatgtt
     1201 tttaccatag catctgctgc agtaacgcct gtagatgtgg ttttaaattc aatcattccg
     1261 attgctttac tcattttgtg cacgtccttt ctactttact gcaataataa tgtaacggtc
     1321 tgttacttct gttactttac cgctgacaga agcatgaata ccaacgctta agccctgtgc
     1381 cggctgtgcg atcatctgcc ctcttattac ctcatcaccg gctttgacca ctgcctgtgc
     1441 aggtgctccg atgtgctggc tcaataatat ccttactttc ttaacctgta caagttcttc
     1501 tttcagagga gcatccttgt catatctcgt aagaccaagt cgcgccatca gacgttcttc
     1561 cggaacctta cggtattctc tggattcctg taccggtttc ggctgtacac cctgcggagg
     1621 acggatacct gcttttctca gaccgccctt catatctgcg agaagacttc tcggtgcaag
     1681 actctgcgga catgagtaca tctcacatac accgcaggaa ctgcagaagg aagcatctat
     1741 atatggattc aggtctctga aatcattatt tgatgcagct ctcataaatt tcgccggatc
     1801 gatcggatgt cccagattat gtctcggaca taaatctgta caggtattgc actggcagca
     1861 gatagatgct gcacgtttta aatctatcga agaagtccgc tgtttcttcg ctacaataag
     1921 atggtctttt ggaaggacca aaatcgcatt tgttgtcttt gtcaccggat ctgaaccatt
     1981 tccgatacgc cccatcatcg ggccgcctac gaaatagaca ggatccttca ctgttgtgct
     2041 gcctgcctgt gctaccactt cctccagagt acatcccagg ggaactctca ctgtaacagg
     2101 atcacttact tctgcaacaa cagatacata tttgtctgta accggctgct tctcttccac
     2161 agcacgatat acattgtata cagtttcaac gttaaatacg gctactccct gctcgatcgg
     2221 cagtcctccc ggccgtacta ctcttccggt tgcctcataa ataagtacaa cctcatctcc
     2281 catcggataa acttcgtcca gaagatgcag cctcatgcca ggaaattctt caatatgctg
     2341 atttaatgca tgaattgtct gtacataaga cttcttaatt ccaataattg cttcagaagc
     2401 accaaccgtc tcctggatca tatggaatgt tttcataatt tcatatgcgt gtttttccaa
     2461 taactgtctg tgtaatttca gtaatggttc acactctgca cagttcataa gaatggtatt
     2521 ggccttgtct gtaagcttca tataagtagg gaatccagct ccgccggcac ctaccacacc
     2581 attctgctgt ataatatcct gtaattcttt gatttccatg gcgttactcc aatcctgcac
     2641 cgtcatcaat aataccgaca attgcggcat ctaccggtgc tgtttctacg ccgcagccta
     2701 ttcttgctgc gcttccctgt gccaccaata catattcacc aactccggct ccgatcatat
     2761 cgatcgcaac cagctggctc aggtcgcctt tcatatgatg cacaggctcg ataatcataa
     2821 atttacttcc aatcagcttc tcactctttc gtgtggatac cacacttcct acaactttgc
     2881 ctacgatcat atgagcctcc aaattatttc tgataataat attgggggca aatacttctg
     2941 cccccaatta acgcttaagg gtttctgttc aaaaacctta tcgtgcaggc acgaacggct
     3001 ttttgacctt tggcccccga tattatttaa ttattgttac ggtagtgcct gtagcaatct
     3061 ttgctgcatt tgcttcatct gtatcaatat gcatttccag tgtaaagctg tcgtctacac
     3121 ggatcttgac ctgattgaag atggttcctc tctcattatc tgcctttact gatacgatat
     3181 cgccgtcctt cacacctgca gcctgtgcat ctttcggaga catatgtata tggcgcattg
     3241 ccacgataca tccctctttc agataaacgg ctccttttgg acctacgatt gcgattggtg
     3301 cacttcctgc aacgtctccg gattcgcgaa ccggaacatt cattccaagc ttaatggcat
     3361 ctgtcgcaga tacctcaacc tgtgaagctt tacgcaccgg tccaaggatt cttacattct
     3421 caatggcacg aagtttcagt cccacaatgg taactgtttc attagaagca aactgacctc
     3481 ccatcagctc tttcttcttc gtaagctgat atccgggtcc gaacaatgct tctacatgtt
     3541 cctgtgtcag gtgaatgtgt cttgcggaaa ccccgatggg aaccatgaat ccatcgcctt
     3601 ttttttcatt ctgattgatt gcctgaatga ccattctggt aatcagttca atattattag
     3661 attccaagaa tacacctgct ttctgtcaaa tatgacggat tataaccatc cggcagtctg
     3721 ctgtgcagat accggacagt tacgatggat tactatttta atacaggcag gattttctct
     3781 acatctgtat gtggtcttgg tattacgtgt gtagcaacta attcaccaag tctggatgct
     3841 gctgcgcttc cgctttctac tgctgattta acagctccta catctccacg taccataact
     3901 gttacaagtc cggatccgat cttctctgtt cctactaatg ctacgttagc agccttgcac
     3961 atctggtctg ctgcttcgat tgcagctgta agtcctctgg tttctaccat tcctaatgct
     4021 tcctgtgtca taactttttc ctccttatga gatactgttt cctttatctg ttctttctgg
     4081 gattctgttt tatttgctgt ttctgccgcc gtatctgccg tctgagcttt tacttccggt
     4141 tttgaagaag tttttgcttt cgttcttctt ggagcggctg cctttttagg ggcattttta
     4201 tctgcttccg gtttcttctc ttcagccatt attcatcccc ctgattgttc ttccagcgac
     4261 ttgcacttaa ttccaccatt ctgacgattt cttcgtgggg acgtgcaatt actgcataac
     4321 ttaccggttt cttgatcgca cctgtcgctg ctgcatttac tgcttctgta acggcagata
     4381 catcgccttc aactataata gtaaccagtc gtccgcccag cttacgttcc catgacgcca
     4441 gctcaacgtc tgcagttttg cacatgatgt ccagtgcatc gattgctgca acgacaccag
     4501 tgatttctat aaatccatat gatttactca tgagcgaact ccttttttat acttctcaat
     4561 ctgctggtca gatgcttgga aggattttct ctacgtctgt atgaggtctc ggaattacat
     4621 gagtagcaac taattcgcca agtctggatg ctgctgcgct tccgctttct actgctgcct
     4681 taacagctcc tacgtctccg cgtaccataa ctgttacaag tccggatcca atcttctctg
     4741 ttcctactaa tgctacttca gctgcttttg tcattgcatc agctgcttca attgctgctg
     4801 taagtcctct ggtttctacc attcctaatg cttcctgtgc catttctgct tcctcctgaa
     4861 tctacaaata aatatctgat tatattttaa ctgatgccca atggatatgc aactgctaat
     4921 ccttatccag ggcgctgatc ttcagcattt tttccgttcc ctcttccggg ttcgggatca
     4981 cataatgctg taccacacca gtcattctgt ttgcaacttc catgcctgct tccacagccg
     5041 ctgtaacatc agttacactt cctctgaatt taatgcagac aaggagcggt accggcaggc
     5101 tgtcagcatt ggctggtttg tttttatcaa aaacctccag gcggacattt gctgccttac
     5161 atccggcatc gcctgctaca aaggctgtcg ccaacccgaa tacctctaaa attcctacag
     5221 cttctgccat ttcttttctc ctctattgcc aggcttatta tttgttgcta ctgttcactc
     5281 cgttcacagc aatactcttt gcgggatatt accggtgaac agtaactatt tgtttacaac
     5341 tgcgatctta agtcctgtca ttgccaggtt tgtctgaaga gcttcattga tctgctctaa
     5401 cgggaactta tctgtgatca gttcagacat cggaagacca attgcttttg ctctcttaag
     5461 gaaatcaaag gttgttacat aatctctcag agtatacacc caggaaccaa ccaggttgat
     5521 ctctttggag cagaggtcaa agtgcggatt aattgtagca tctccaccat tgatgaagaa
     5581 gccaagttca caaagaccac caccattgcg gataaattta taaatgtttg catgagcttt
     5641 cgggtttcct gtgcactgga atgcgaaatc tgcaagatgt ccgccctgag cttcttttac
     5701 agcttctgtc agtgcttcga ttcccttaaa gttcatgaag ttaacgcttg tgtctgcacc
     5761 cattctcttg gcaaattcaa gacgtttctc atttccgtct actgcgcaga tatgttcaac
     5821 ccccatagta cggagtactg caatgcagat cagtccgatc ggtccgcagc cctgaacaac
     5881 tactctgctg ttgaaacgaa gaattcctgt tgtttttgct ctctctactg catgtacaag
     5941 cactgcacat ggctcaatga gaattcggga atccagatcc agatcactta cattaaagaa
     6001 tgtagttccg aagtttccgc ctcttaagaa gatgtaatca gagaaccatc cgttgagatg
     6061 tacatcatcg tcaggaagaa gtccgtatac atcagctccg cctacgttct tcttgttcag
     6121 gtcaaacatt gtaatatcag gatcatcctt gaagatcata caggtaacaa ctttgtctcc
     6181 aacctttaca ggttttcctg ctgtgtcaac tttaacattc ttacccattg ccacaatctc
     6241 acctgtacct tcatgtccaa gtgctaccgg gatcaggtta aacggatctc tcttaaattc
     6301 gtgtgcatct gtaccgcata cgccgcatcc ttcaacttta accaggatat catcatctcc
     6361 gattggcggg attggatatt ctttgatgtc aaaatgctct ttctcagtta atacagctac
     6421 tctggctgtc ttcgggattc cagttgatgc tgccggtgca gaagctgctg ccggtgcatt
     6481 tcctgtcatg ccggagagaa cctgtttcac gatttcttct atatttacat tattcatgtc
     6541 catgttcttt ctctccttat atcaattctt atcgaataca gagactgtct gccattacgc
     6601 agcgtcttct cttggtgaat gtgcttgcgc atgtaaggcc ttcacctgta cggcttgcaa
     6661 tggtaaatgt acagtagcct tcaccgccaa atcccaaagc tgcataagac ggtgcattct
     6721 taacaagaat tgctgtatca attgctttcg catattttgt gatgttatca atattctttg
     6781 aatgaatatg tgcggaatga cgattgccat gttctaacca gactgcctgc tctactgcat
     6841 catcaaaatc tcttgctctt acaacaccga ggatcggcat catcagctca gtagtgatca
     6901 gagggtgttc ctttggcccc tcaaatacga tacagcggat atttgcaggt acatttactc
     6961 caatcatgga aaggagtgtt cttgcatccc ggcctacgca tttacggttc agctttccgc
     7021 ctgccagaac aacttctgta agtttgtcct gctcttcctt agaagcaaga tagcagtcat
     7081 tctcagttac aagatagtgc atcagctcat ctacgataga ggaaactgct acgatctctt
     7141 tctcggcaat acatggaaga ttgttatcaa atgtacatcc gtttacaata tctgtggctg
     7201 ctttgcggac atcagcggtt tcatcaacca gtgccggagg atttccggcg cctgctccga
     7261 taccacgttt accggaagaa agaactgcag ttacaactcc aggtccgccg gttgcagcga
     7321 taagcgggat gtctttatgt ttcatcatca cattgcttgt ctcaagtgta ggtttctcta
     7381 cagtaactgc aatgttgtca ggaccaccgc actctaatga tgcttcattt aaaagattga
     7441 ttgcataaat ggaagttttg atcgctgcag gatgaggatt gaatacaact gtatttcctc
     7501 ctgcaagcat tcccattgta ttacataaaa ttgtttcact tgggttggta catggagtga
     7561 tcgcaccgat cacaccaaaa ggtcccatct cgataagggt taatcctctg tctccggacc
     7621 atgcagttgt tgtaataact tctgttccgg gagtcttgtc agctacaaga tgatgtttga
     7681 ggatcttgtc cccaacattt cccatacctg tttcctccac gcccatacga gccattactt
     7741 ctgcgttttc ttttattttc ttacggatgc aggtaattat tttttctctc tgatccatgg
     7801 acatcttctt tacgataagc tgtgatttct tcgctgcttc gatcgcatca ttcatttctt
     7861 tgaaaatacc atgtttacca gtcggagcgt ctgcaatctg catttttgcc attacttcct
     7921 gtacaatttc ctgtaccata ttctcattaa ttggcatgag actgtcctcc ttgattatcg
     7981 gtcatctata ctcttatttc attcctaact gagccattac ctgttttgtg atctcagcaa
     8041 ctaattcagc ttcagatttg tctgctgttc ctgctgccgg ctgggaatct ccgccgccta
     8101 cgaaatcata ctgatatcca gggaatttct tgaattcgcc gtcatgacat gcgccgccgc
     8161 agttatggca gttatggcca tctttattca ggcagaggtt tgcaggatgc ttgcctgcca
     8221 taccgaattt acggcggatt tcatacagtt tcttaatgtt cttctcatca aattccttag
     8281 gtccgccaag aacttttgac tgatacagaa gctgtgcgta gaactcaaca gattccatct
     8341 tcatgtaagc tgcgtttaag tctgtgctcc atgtcagtgc tccatggttc tcaagaagaa
     8401 ctgcatcgaa atatggaagg tatttctcaa gattatccgg aatctccatt gtagatggtg
     8461 taccgtattc agcgatcgga acgcatccaa gtgagataac tgcttcaggc atgatcggct
     8521 gtgtcagcgg aatacctgca attgcaaaag atgttgcata aatcggatga gcatgcacaa
     8581 cagaacctac gtccggtctc ttctcataaa ctctcatatg cattttgatt tcagaggatg
     8641 gtttgaatcc cgggttagcc tggatcacat ttccttctct gtctacttta cagatatact
     8701 ccggtgtcat aaaacctttg gatacacctg taggtgtgca aagaaattcg ttgtcgttca
     8761 gttttacaga gatgttacca tcgtttgcag ctaccatgtt gcggctgtag attcttcttc
     8821 cgatgtcgca gatctgtttt ttgatttcat attcgtttac catgctcatt ttcctcctta
     8881 aggcattgat atagtttttg acgtttctac ctgtgatttt acactatcgg tcataaaaag
     8941 tcaatacatt tccgttgttt tatgttgttt ttacgggttt tattgtgttg tttttgtttg
     9001 tttttttctt tttttattcc aataatcgta tcagatgcaa aaaatacctc atccaccgat
     9061 ctgacagtcc agaccgcaga ccgcatgtac tgcctttttt aatgtttcca tatgttcttt
     9121 ggacggtggt tccacatttc ccatcaaata tggtctgcca agtccctcat atttatcctg
     9181 tccaagtctg tgatacggaa gaagatgaat cttgtccact ccgggaagtg tgtctgcaaa
     9241 ccttgcaatc ccctggattt cctccactgt atcattaaat gtgggtatca ccggtacacg
     9301 gattaccagc ctggttttac cggaaagcgc cacttttctg gcattttcca tcatcagttc
     9361 attggaacgt cctgtaaatt ctttatgttt cgcaggattt gtatgtttaa tatccattaa
     9421 ataagtatcc agatacggta agattgtctc aatcgtctcc cattttgcac atgccatact
     9481 ctcgatcgca gtagaaatcc ctctctcttt ggcagctctc agaagcgctc ctgcaaattc
     9541 cggctgacag agacattctc cgccggaaag agtcatacct ccgcccgagc ggtaatagta
     9601 taccctgtct ttctcaactt cttcaatcat ctccctgact gtcacatcac gtccgatgac
     9661 cttgtcttct ccctgcactt tcattgtctg gatcttatat tcctgagatt ccggattgca
     9721 gcaccatttg caccgcagga cacaaccttt cagaaatacg atcgtcctta tacccggtcc
     9781 atcatgaata gaatatttct ggacatcaaa cactctgccc tttgtatcca aatagtccat
     9841 gcttttcctt tcttattctg ttatccatac atcctctgcc tgtcactttt acttcctgca
     9901 aaaaacgtct ggatcagaag ccctgttctg tacgacggat gatatcatcc tgaagagaac
     9961 gggaaagtgt cgtaaacagt gcactgtagc ctgccacacg tactaccaga tgtttatatt
    10021 tctcaggatg ttcctgtgca tccagcagtg tctgcctgtc aactacatta aactgcatgt
    10081 gcattccctt ctggtcaaag tatccgcgga tcagtgcaac gaatttctcc agtccctctc
    10141 ttcctgaaag tgcggatggg tgaaatttct gattaaagag tgttccgttg gatacaataa
    10201 aatgatccag tctggatacg gaagttgccg ctgccgtagg tccctttaca tccttgcccg
    10261 cagatggcga aacgccgtct gcaacaggtg tgtgtgcata tcttccatcc ggtgttgctc
    10321 cagtctgtcc gcccagcggt acatttgcag atacaggata cagacctgcc tggaactttc
    10381 cgcctcttgg attgttatac ctctgaagcg gtttggaata tgtataggca acttctcttg
    10441 caaaataatc aacttccgga atatcatttc caaatttcgg aacttcatcg atcatatcat
    10501 ggatttcttt gaatctctgt gtcttctgtt cacccggttt cattcccatg aaagttttca
    10561 gaagtccttc tgcagtggaa gcatccacat ttctgcctgc tttctgcatt gccttcatga
    10621 tcatctctgt catatcaccg gcggactgcg catccagtcc tttatcatag ttccatgcaa
    10681 gagcttcctt aagttctttc atagatactt tcttatcctc atagaccagt ttgcggattg
    10741 caaaaagtcc atctgccata ttggcgattc caaatccctg aggacctgta aagttgtaaa
    10801 cagctccacc ttcctggaca gacttgcctt ctttcagaca gtcatctatc atacaggaaa
    10861 ggaatggtaa cggacagcgt tccgcatgag ctacatcaat agcattatct gcattcacca
    10921 gcagggaaat gcagtattcc atctgtttct tatatgcgtc aaagaattca tcaaaggtct
    10981 tcatctgggt gacatcgcct gtggggattc ccaccatctc acctttatcc ataccattcg
    11041 aaaaaacaag ttccagaggt ctgcacatat taaagaatgc ggcatcatgc cacccttctg
    11101 tcttaccggc tttctgcggt tccacacatc cgatgatatt gtactctctg gcatcctcca
    11161 gagataagcc tctgttctgc agtgccggaa taatcacctc atcattgtaa tatgcaggaa
    11221 gtccgattcc tgttctcgta agctcggctg cctttatcag aaattcatgt ggagaaccat
    11281 tccatactct cacagaaagt gatggagccg gaagatgcac atgcatggat gcctgaatac
    11341 acataacaga aagatcgtta gttacatcct ctccctcttt attctgacca cctgcgatca
    11401 gattctggaa aaggctgtat cctgcaaatc cttccgctga agccgcatca cgacatttat
    11461 tcaggtcatt taatttaacc cagatgcaat ccatcaattc ctgtgcgaac tctcgggtaa
    11521 tagttcctgc ttccatatcc ttcttataat atggatacat atactgatca aagcgacccg
    11581 gtgaaataga atgtccactg gattccatct gaagaagctg ctgtacaaac cagaatgact
    11641 gacatgcctc ataaaaattc tgtgcaccct ttgccggtac cctgctgcag ttctctgcga
    11701 taacaaaaag ttcctgtttt cttaccggat cacttgtctg tgccgccatt tcctgcgcaa
    11761 gttttgcata tctgcctgca taatcgatca ccgccttaca gcttaaaatc actgcctcaa
    11821 ggaagtgaga ctttcttgca taattaccgt caccgacact gcatccatcc agctctttct
    11881 gagccttctc catgattccc tcaaaaccgg tttccagtac ttcccagtat ttaactgtta
    11941 catgtcctac accattgtaa aaatagttcc caggtgtaaa aatattgtgt tcaattgcct
    12001 tgattgcttc cggtgccata taggaagttg caagttcact ggttgttttc cctttccagt
    12061 acttatctgc ctccttaagt tcggctttgg tctcctcagc aatctcaaaa ggatccgcag
    12121 ttctggtcgc aactgtatcc agttcagctt ccagccactc ataagagaac tccggaaatg
    12181 tctgacatcc cctcggcgca atcgtactgc ttccgacaat cagttcattg tcacggataa
    12241 tgatcggaat gttatgaaga atatgcgcaa aagcctttgc tctgcgtgtg atgatcggtt
    12301 ctccttctgt ttccttataa gattctgtga tcagctttgc tctggctgat tcgatcaccg
    12361 gcatatgttc atacaatgca tctaccagtt tctgaattct gggagacttg ggaatatctg
    12421 atgtttgaaa tttttccatg ttactccttt ctcatgaata aaagctgcac ccataccaga
    12481 ccccaataca ttccggtatc attctgacag caatatcctc catgttttca tatagattca
    12541 ttatacctta tggctatcgc aaagtcaaca taaatcaaca tgtacatcct gaacttttat
    12601 gttgtttttt atttgttttt tcttctgttc tggttgtttt tgttttgttt ttatgattga
    12661 catttcattt ttcttcagac acgttaaaag cagcatatca ggttatgatc cataactctg
    12721 atatgctgcc ttttaatatc gtatattgtt ttttctgcat cggatgactt taatgagcat
    12781 gcttttccat cgctgcactc ccatatattc atatacactt aactattgtt tcctgttctc
    12841 tttttgttct ctggcttctc ttactttctc cctctgtttc gtcagatcgt aataatcatc
    12901 tgtaagaacc ccatgttttc gcatcatatc aaacacagtc tgctgagcag gtgtcatctt
    12961 catgccaata gaattattat aatccgtaag aacgcatcct gttttctcaa tcagccagaa
    13021 cagcggagaa tcatcatccg ggatcatttt ccagatttcg ttctctgtcc atggaagcaa
    13081 ttccatcatt ccatgaagat gtcctctggg tattcttacg taatcgccgt ccggcttgat
    13141 cagaccgtca gaaaagttct catccttaat tttcatctca tttaacagtt cttctgttat
    13201 cttcatcctc ttttcctcac cctcgagtat tactttttcc tattatacgt ttcccgccag
    13261 agttacgcaa gtaaaaagtc tgaatagcct ctttcctcaa aaatatatgt tactgttcac
    13321 tccgttctca gtaaca
//
