LOCUS       c00053_gnlPro..        15148 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDKPAMKK_53.
ACCESSION   c00053_gnlPro..
VERSION     c00053_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:14:18
            Original ID  :: gnl|Prokka|GDKPAMKK_53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15148
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15148
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2469:11545]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2470..11545
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15148
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15148
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(3..497)
                     /locus_tag="ctg53_1"
                     /transl_table=11
                     /translation="MENVYIMNHPLIQHKISMLRNKNTGTNEFRKLVEEIGILMGYEAL
                     RDLPVENVEVETPIETCMTPMISGKKLAVIPVLRAGLGMVNSILTLVPSAKVGHVGLYR
                     DPVTHEPHEYYCKLPEAIDERISVIVDPMLATGGSAEAAVDFVKKQGGKNIKFMCIIAA
                     PE"
     CDS             complement(545..727)
                     /locus_tag="ctg53_2"
                     /transl_table=11
                     /translation="MSDAVNCEYCVNYSYDDDYECYTCEINLDEDEMVKFITGNFNQCP
                     YFKMGDEYRIVRKQM"
     CDS             918..2018
                     /locus_tag="ctg53_3"
                     /transl_table=11
                     /translation="MILYHISAKKLITRCTFSMLAASLILCPAVFSGCSAKTENVKNTD
                     AGSQNPISATAIKLNTAVTVTIYDSQDRELLTECMNLCDKYEKIFSRTADDSELYQLNH
                     RELTPVKGTKDTYQVSASLAELVSKGLDYSVLSEGAFDIAIEPLTSLWDFTAENPKAPK
                     DSLIQAALPKCNYHNISVDTDKNEITLKTDDTAIELGAIAKGYIADRLKDYLVSQNVKS
                     AIINLGGNVLCIGEKTDNSAFKIGIQKPFADRSETIAVMDIRDKSVVSSGIYERCFEQD
                     GTLYHHLLNPKTGYPYDNELIAVTIISDQSVDGDALSTTCFALGLEDGMKLAESLDDVQ
                     AFFVTSDYEIHYTRDFQKKIKVTETE"
     CDS             complement(2406..2531)
                     /locus_tag="ctg53_4"
                     /transl_table=11
                     /translation="MPMTPNTEQDWKVWRNLMWSEILTESVKSYMDCKCLNAISI"
     CDS             complement(2470..3987)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_5"
                     /sec_met_domain="Fer4_7 (E-value: 1.7e-11, bitscore: 35.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2e-11, bitscore: 33.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.1e-06, bitscore: 16.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGLYSSKTEIRHKIFTEIARMAYEGQSPEMLEELPYKIVPGEIA
                     SYRDSIFLERAVVGERLRVAMGMSLRKVTEHAPISKGVEASVIEEKYYEPPLINVIKFA
                     CNSCPEKRVMITEGCQGCLEHPCVEVCPKKAVHMEGGRSHIDEDACIKCGKCLEACPYN
                     AIIKQERPCSKACGMNAIGSDEYGRAEIDQDKCVSCGQCLVSCPFSAIVDKGQIFQTVM
                     ALKSETPVYAIVAPAIAGQFPGMENNKIRGAFQALGFTDVREVAVGADLCTVEEAKDFL
                     EEVPEKLPFMATSCCPSWSMMAKKLFPEQAKCISMALTPMVLTARLIKQKEPDCKIVFV
                     GPCAAKKLEASRKSIRSYVDFVLTFEEVAGMFDAKGVDWKDIPEGEPLFRASADGRGFA
                     VSGGVAKAVVNAVKRIDPDREVKVMNAEGLQNCKKMLQMAKIGKYNGYLLEGMACPGGC
                     VAGAGTIQTVKKAAAALEKMKKEALFTDAYDSKYRARLESLEKFDVE"
     CDS             complement(4058..4147)
                     /locus_tag="ctg53_6"
                     /transl_table=11
                     /translation="MSGISFLCEEAESSAGGKMSVLIAAVMKL"
     CDS             complement(4253..5017)
                     /locus_tag="ctg53_7"
                     /transl_table=11
                     /translation="MIFTKKYRTGQIVLTACIAAVCMFSNVHGAEVAGPPAPKSKSALT
                     QKPEATLIPASTPTPEQEAKTDKQNPADQGTLSKPDHPDTISADKLVFIGDSRTEGLRD
                     AVNDDSIWSCLSSMGYDWMVSTGVPQVEDQIEDNTAVIILMGVNDLYHVNDYISYINSK
                     AAEWGNRGAQTYFVSVGPVQNDPYCSNAEIESFNAAMQANLSGVTYIDVYSHLVSEGFS
                     TVDGTHYPDSVSVDIYNYILDHLEEQRSGIWG"
     CDS             complement(4995..5123)
                     /locus_tag="ctg53_8"
                     /transl_table=11
                     /translation="MAGYAAWDVSMLLFTATHSRELRYVKSNVSITAEGNDIYEKI"
     CDS             complement(5096..5350)
                     /locus_tag="ctg53_9"
                     /transl_table=11
                     /translation="MRLEKVQEALKTKKIHYEYTEENGCGSIDFMFRGLRFHIWEYEDR
                     VWGAETNVFEAGRSQDIEGDYEEIISGEILSWPDMLPGM"
     CDS             complement(5622..6269)
                     /locus_tag="ctg53_10"
                     /transl_table=11
                     /translation="MLCQYSYFQTIEWSNAGTATVIQYLGPALIVVWVCFRTKRLPQKK
                     EVLGVFLAVTGIFLIATHGNPTSLALSQKALAMGLLSAVSVVVYTIKPARLQAQFPTPL
                     VLAWGMLIGGAVLMAVFRPWDYQVIFDRETFAAVAFIILFGTMAGFSLYLTGVKMIGSV
                     KASLVSCVEPVASMVLTAVWMKVSFTTPDLIGTLFVIATIIILAIPTKKRQK"
     CDS             complement(6328..6555)
                     /locus_tag="ctg53_11"
                     /transl_table=11
                     /translation="MQTNNESKQNQKKEMMLGTFLTIVGGILWGISGVCGQFLFQNKEV
                     TAAWLVPIRLVTAGLLLLCYYFFKDKGKNI"
     CDS             complement(6700..8340)
                     /locus_tag="ctg53_12"
                     /transl_table=11
                     /translation="MKGLLKFITCGSVDDGKSTLIGHILYDAKLLYADQEKALELDSKV
                     GSRGGAIDYSLVLDGLMAEREQGITIDVAYRYFTTDNRSFIVADTPGHEEYTRNMAVGA
                     SFADLAVILVDASQGVLVQTRRHARICALMGIRYFVFAVNKMDLIEYDEKRFRDIENQI
                     AALIEELKLANVTIIPVSATEGDNVTTKSDNMPWYKGEALLSHLETVDIKEDTEKGFYM
                     PVQRVCRPNHEFRGFQGQIENGVIRAGDLVTTLPSKEEAHVKSILVGDKEVQEAVQGQP
                     VTIQLDREVDVFRGCVLTIDSGAVLTDSVEADILWMDDNDLTDGRNFFVKIGTKMIPGL
                     VTKINYSVDVNTGEKKSAYTLKKNEIASCTLEFSEKIVVDEFDRHRTLGELILTDRVTN
                     MTSACGVVRKTFVSQDRSQIGKVDEQVRAGLKGQTPVVVEFPIGKEGITLDFAEQVEKG
                     LTVLGKHTYLYHPAASENYAETVRHLKAAGLIVLLVLDENTAKDETLKTLDGFYANWQI
                     DGITVKDAIDFVKKKSAFTVQSVQDGNYI"
     CDS             complement(8337..9458)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAPS_reduct"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_13"
                     /sec_met_domain="PAPS_reduct (E-value: 5.7e-65, bitscore:
                     208.9, seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCLKNALRKMCVTICGRFCSDEGVVAGYDNRIRTKSPAKWGVQIA
                     GMIFQTRSSVFAQVRKDSEYKQTEEDNAMSNLSHLDAPEAEAIYIMREVAAECEKPVML
                     YSIGKDSSVMLHLAMKAFYPEKPPFPFLHIDTTWKFHEMIEFRDRIAKENGIDMLVYTN
                     EEGVKAGINPFDNGSAYTDIMKTQALKQALTKYGFTAAFGGGRRDEEKSRAKERIFSFR
                     NSAQAWDPKNQRPEMWKLYNTKIQKGESMRVFPISNWTEKDIWQYIQRENIEIVPLYFA
                     KERPVIYRDGNIIMVDDDRLKLRPGEKIENKKVRFRTLGCYPLTGGIESEADTLDEIID
                     ETLSAVSSERTSRVIDHEAAGSMERRKRGVFLG"
     CDS             complement(9489..9803)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_14"
                     /sec_met_domain="Fer4_9 (E-value: 2.5e-13, bitscore: 40.4,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.7e-09, bitscore: 26.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.4e-05, bitscore: 14.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRIQKSKCAGCGRCIEACPGNLIKKDKENKAFIRQVRDCWGCT
                     SCIKECRHDAIRFFLGADVGGRGASMVVSEKTDISTWTVEKPDGTKITIQVNKKDANKY
                     "
     CDS             complement(9800..11545)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 71.9; E-value:
                     1.9e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_15"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.7e-23, bitscore:
                     71.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.9e-08,
                     bitscore: 24.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTERIRTDVLIIGGGTAGCFAAYVIGKKSGRKVLIAEKANIKRS
                     GCLAAGVNALNAYITEGRAPQDYVDYAKKDAHGIVRENLLLTMSERLNHVTKVMEDLGL
                     VILKDENGKYVARGNRNIKINGENMKPILAKAAAEQENVTVLNHVNITDYKTENKKVTG
                     AVGFSVNEDIFYDIDAKAVLCATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGLLS
                     GAEMTTFEMRFIALRCKDTIAPTGTIAQGVGARQVNAHGDIYETKYGLTTSQRVYGTVM
                     ENREGNGPCYLRTEGISKEQEQDLYKAYLNMAPSQTLKWMEAGKGPSEENVEIEGTEPY
                     IVGGHTASGYWVDNNRATTIEGLYAAGDVAGGCPQKYVTGALAEGEIAAEAILEYLNGK
                     DDDRIAAENKKEALEHGEEQKLSQTATAKKAEYESHLNASRSLMNAEQLEEAMQKIMDQ
                     YAGGIGTDYRYSEMSLAKADEKIAALLPVADTLAATDTYELMQIYELRERLIVCRAVIA
                     HLAARKETRWHSFGENTDYPQQSKEWMKYVNSRMENGEIKILYRDLITKENTGLNTAEK
                     GAGER"
     CDS             complement(11657..12715)
                     /locus_tag="ctg53_16"
                     /transl_table=11
                     /translation="MYVELKNINKTYGSYQASRNVNFGIEKGKLIGLLGPSGSGKTTIL
                     RMIAGLETPDSGEVIIDGKVVNDVPASQRGIGFVFQNYALFRYMTVYDNVAFGLKVQKA
                     DKKKIDTRVRELIKLVGLEGLEKRYPSQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKIRQELRSWLKEMIGKLGITSIFVTHDQDEAIEVADEIIITNAGQIEQKGTPIGVYR
                     NPETAFTASFFGQPSVLKNADDFHTFAQAEGADKIIVHPEFVKISKLDEVEKFKTSVSR
                     GVVERVSFRGDNLELQVRVNNSVVTARRSLEKADIREGETVNVFLYRIFALRGDSVQLI
                     ENEAVRDDFVII"
     CDS             complement(12717..13541)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 59.9; E-value: 8.7e-19)"
                     /gene_kind="transport"
                     /locus_tag="ctg53_17"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.7e-19, bitscore:
                     59.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNNEKTSAKIIKWLLVGISVLFLAVMLLLPLITVITEALRSGWK
                     VYAAAVTDEYTIKALLLTVKATIFAVVFNTVFGVFAAWALTKFQFRGKKLLTTLIDLPV
                     TISPVIAGLIFLLIFGRQSPVYFFLMKLGIKVVFSVPGIIIATVFVTFPFISRELIPVL
                     EAEGSDEEEAAALMGAGGWTIFWKITFPHIKWALLYGVVLCTARAMGEFGAVSVLSGHL
                     RGKTNTLPLHVEILFNEFQYVPAFAVSSLLVIMAVIILVARSLIEYKGKKEA"
     CDS             complement(13541..14377)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 85.1; E-value: 1.7e-26)"
                     /gene_kind="transport"
                     /locus_tag="ctg53_18"
                     /sec_met_domain="BPD_transp_1 (E-value: 5.2e-27, bitscore:
                     85.1, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRNKPVIPGFGLSMGITISILSLVVLIPLASLVVYTAKLSFKD
                     FIETITRARVLASFYTSFVCAFAAAVINGIMGTILAWVLVKYDFPGKRLMDGMIELPFA
                     LPTAVAGIALTSLTSDSGIVGSFFAGFSIKIAYTRIGITVAMIFVGIPFVVRSVQPVLE
                     KMDNSYSEAAGVLGAKKTTIFWKVIFPELKPAIFAGTGLAFGRCLGEYGSVVFIAGNKP
                     YYTEITPLVIMSELQEFDYSSATAIALVMLAVSFFILFLNSMIQQRNARILRGGNA"
     CDS             complement(14448..15146)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SBP_bac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_19"
                     /sec_met_domain="SBP_bac_1 (E-value: 4.3e-11, bitscore:
                     33.6, seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IKAGWKDKFDNDSSPYTSTIVFLVKKGNPRDIKDWDDLTKKGVGV
                     VTPNPKTSGGARWNYMAAWAYADKKYGGDEAQMKEFIKKLYRNVVVLDSGARGATTSFV
                     ENGQGDVLVAWENEAYLSMRDYPDEYEIVTPSVSILAQPSVAVVDEVVDYRDTRDVATE
                     YLNYLYSDEAQEIAAENYFRPTNEKILKKHSDTFDLNINLANISDYGGWDKVQKKHFTD
                     GGIFDQIYER"
ORIGIN
        1 ccttcagggg ctgcgatgat gcacatgaat ttaatgtttt ttccgccctg ttttttgaca
       61 aagtcaacgg ctgcttctgc ggagccaccg gttgcgagca ttggatctac gatcactgaa
      121 attcgttcat caattgcttc cgggagtttg cagtagtatt cgtgtggttc atgggttaca
      181 ggatcacgat agagtcctac atggcctact tttgcagatg gcacaagtgt gagaatactg
      241 tttaccattc caaggcctgc gcggagcaca gggataaccg ccagcttctt tcctgagatc
      301 attggtgtca tgcaggtttc aataggggtt tctacttcta cattttctac aggaagatcc
      361 cggagagctt cgtatcccat gaggattcca atctcttcta ctaatttacg aaattcattt
      421 gttcctgtgt ttttgtttct cagcatggat attttatgct ggatcagcgg atgattcata
      481 atataaacgt tttccattat cttaattcct cgcttagttg aatatttgtt actttttata
      541 aattctacat ctgcttacgt acaatgcggt attcgtcacc catcttgaag tatggacact
      601 gattgaagtt tccggtgatg aacttcacca tttcatcttc gtcaagattt atttcacagg
      661 tgtagcattc atagtcgtca tcataactgt agtttacaca atattcgcag tttactgcat
      721 cggacattat ttactcctct ctttgtttcc ggcatatttc atttctatcc ggtatctcct
      781 tttggatttt ttatgttgcc tttgtacctg tgcaaagttt gctgtttctg atatactatg
      841 gtgttaggat caaaagatat ttcttccctg aactattgct tatagcaatt ccataaaata
      901 actatgaggt tacatttatg atattatatc atatatctgc aaaaaaatta ataacacgct
      961 gtactttttc aatgctcgca gcatctctta tattatgtcc ggctgttttt tccggatgtt
     1021 cggcaaaaac ggaaaatgtc aaaaatacgg atgccggttc ccagaatccc atctctgcca
     1081 ctgcgatcaa actgaatact gcagttacgg tcactatcta tgattctcag gacagagagc
     1141 tgcttacaga atgcatgaat ctttgtgaca agtatgagaa aatattcagc cgcactgcag
     1201 atgacagtga attatatcag ttaaaccatc gggaacttac acctgtgaag gggacaaagg
     1261 atacttatca ggtgtcggct tctctggcag agctggtttc taagggactt gattattctg
     1321 tattatctga gggtgcattt gatattgcta ttgaaccgct gacttctctg tgggatttta
     1381 ctgctgaaaa tccaaaagcg cccaaggaca gtctgatcca ggcagcactg cccaaatgta
     1441 attatcacaa tatctctgtt gatacagata aaaatgagat tacattaaag acagacgata
     1501 ctgcaatcga actcggtgcc attgccaagg gttatatcgc agaccgcctg aaggattatc
     1561 tggtttctca gaatgtaaaa agtgcgatca tcaatcttgg cggaaatgtt ctctgtattg
     1621 gcgaaaaaac agacaattct gcttttaaga tcggaatcca gaaaccattt gcagaccgaa
     1681 gcgaaactat tgctgttatg gacatcaggg ataagtcagt ggtttcctca ggaatttatg
     1741 agagatgctt tgaacaagat ggcactttgt atcatcacct gctcaatcct aaaaccggct
     1801 atccttatga taacgagctg attgcagtta ccattatttc cgatcagtct gtggatggag
     1861 atgcgctgag cacgacctgc tttgctcttg gtctggagga tggcatgaaa ctggccgagt
     1921 ctctggacga tgtacaagca tttttcgtaa cttctgatta tgagattcac tataccagag
     1981 atttccagaa aaaaatcaaa gttacggaaa cagaataaat ctatctctga tgacttaaat
     2041 tgaaaaaaca gaaatataaa tcaacaatta ttaactggtg ttttgactta atcaatagat
     2101 tttaattttc aagtcataca atccgcacta atttcttgac ctaatttgct atttataaat
     2161 ttccagtcaa atatttttgc ctgttcgctt gacttaattt gttattctat aaaatctcag
     2221 tcaacatact gttaattatt tcatgactta tatgaaactt tttttgattt aagtcaatat
     2281 tgtacatagc tgacaaaagt cccctgctta ttgcttttcg caatctccgc gggggactta
     2341 ccctattcag ttaaacttat cactcagcct gacagttctt ctgacgatta ttcattttta
     2401 gtctgctata tactgattgc attcaaacac ttgcaatcca tataagattt cactgattca
     2461 gtcagaatct cactccacat caaatttctc cagactttcc agtcttgctc tgtatttgga
     2521 gtcataggca tctgtaaaca aagcctcttt cttcattttt tcgagagccg ctgctgcttt
     2581 tttaactgtc tggatagtac cggcacctgc tacacagccg cccggacatg ccattccttc
     2641 cagcagatat ccattatatt taccaatctt ggccatctgg agcatcttct tacagttctg
     2701 cagaccttct gcattcatta cctttacttc ccgatcagga tcaatacgct tcactgcatt
     2761 gacaaccgct tttgccacac cgccgctgac tgcgaaacct cttccgtcag cactggcacg
     2821 aaacagtggt tctccttctg gaatatcttt ccagtccacg cctttggcat caaacattcc
     2881 tgccacttcc tcaaaggtca gcacaaaatc cacatagctg cggatactct tacggctggc
     2941 ttccagcttc ttggctgcac agggacctac gaaaacgatc ttacaatccg gttccttctg
     3001 cttgatcagc cttgcagtga gaaccatagg tgtcagtgcc atagagatac atttcgcctg
     3061 ttcagggaat aatttcttag ccatcataga ccaggacgga caacaggatg tagccataaa
     3121 cggaagtttc tcaggaactt cttccaaaaa gtcctttgcc tcctccactg tgcacagatc
     3181 cgcaccgacg gcaacctctc ttacatctgt aaagccaagt gcctgaaatg ctccccgtat
     3241 cttattattc tccatacccg gaaactggcc tgcaatggca ggcgccacaa ttgcatacac
     3301 cggtgtttca ctttttaatg ccataacagt ctggaaaatc tgtcctttgt ctacaatagc
     3361 actgaacgga cagctcacca gacattgtcc gcaagataca catttgtcct ggtcaatctc
     3421 cgctcttccg tattcgtcag aaccaatggc attcatgcca caggcctttg aacatggacg
     3481 ttcctgtttg atgattgcat tatacggaca ggcttccaga cacttcccgc atttgataca
     3541 ggcatcttca tcaatatggg atctgccgcc ttccatatgc actgcttttt tgggacagac
     3601 ttccacacag ggatgctcca ggcaaccctg acagccctcg gtgatcatta cccttttctc
     3661 agggcaggaa ttacaggcaa acttgatcac attgataagc ggcggttcat aatacttttc
     3721 ctcaataacg ctggcctcca cacctttgga aattggcgca tgctctgtaa cctttctcag
     3781 tgacatcccc attgcaacgc gaagtctctc tccaaccact gccctttcca gaaaaatact
     3841 gtcacggtag gaagcaatct cgccgggtac gattttgtag ggaagctcct ccagcatctc
     3901 cggagactga ccttcatatg ccattctggc aatttctgta aaaattttgt gtctgatttc
     3961 tgttttggat gaatacagtc ctctcatttt ttcctcctga ttctcaattc ggataactgt
     4021 acggcagtcc actacaggaa caccgaacaa tttccattta taatttcatc actgctgcaa
     4081 tcagcacact catttttcct cctgctgaac tttcagcctc ttcacagaga aacgaaattc
     4141 cgctcatttc cgtttcctta tctgcatatc atatcaccaa atgcttccag gctcaacaca
     4201 acatcgaaat ttgcgctgta ttgtctcccc agaagtggct gttcatatgt tgttatcccc
     4261 agattccact cctctgttcc tccagatgat ccagaatata attataaata tctacagaca
     4321 cactgtccgg atagtgggtt ccgtctacgg tggaaaatcc ctcagatacc agatgggaat
     4381 atacgtctat gtaggtaacc ccactcagat ttgcctgcat tgccgcgttg aaactttcaa
     4441 tctccgcatt actgcaatag ggatcattct gcaccggacc tacagacaca aaataagtct
     4501 gtgctcctct gtttccccat tcggcagctt tggaattaat ataactgatg tagtcattga
     4561 catgataaag atcattaaca cccatcagga taataaccgc tgtattgtcc tcaatctgat
     4621 cttctacctg cggcactcct gtagatacca tccagtcata tcccatagaa gaaagacagg
     4681 accaaatgct gtcatcgttt accgcatccc tcaatccctc tgttctggaa tctccgataa
     4741 ataccagttt atctgcggag atagtgtccg gatggtctgg cttgctcaaa gttccctggt
     4801 ctgccggatt ctgtttatct gtcttagctt cctgctccgg tgttggagta gatgcaggta
     4861 ttaatgttgc ttccggtttt tgtgttagtg ccgatttgga tttcggtgcc ggcggacctg
     4921 ccacttctgc cccatggaca tttgaaaaca tacagacagc tgcaatacat gcggttaata
     4981 cgatttgtcc ggttctatat tttttcgtaa atatcattcc cttctgcagt aatacttacg
     5041 ttacttttca catatctcaa ctccctggag tgtgttgctg tgaacagtaa catgcttaca
     5101 tcccaggcag catatccggc catgagagga tttctccgga gataatttcc tcgtaatccc
     5161 cctcaatatc ctggcttctg cctgcttcaa acacgtttgt ctccgctccc cagacacgat
     5221 cttcatattc ccatatatga aatctcagac cgcgaaacat aaagtcaatg cttccgcatc
     5281 cgttttcttc tgtatattca taatgaattt tctttgtttt taacgcttcc tgtacttttt
     5341 ccaaacgcat aaaatacctc ctgattatct gtacagtacc ctctgtaata taatacagat
     5401 aactttcact gtaaaaaaat gttctcgtgt acaccccatt acataatcaa aactaaaaag
     5461 catactgcaa ctacgattcc cgaatcaaaa atccacaaaa tatgctctta atcctgacgc
     5521 cattatacaa aatgaattat atcatactct gctgcataat atgtaatctg aatgccactt
     5581 cacaattgcc attctacatt ctgattgata ttcactcata tttatttctg tcttttcttc
     5641 gttggtatcg ccagaataat gatcgtagca attacaaaca aagttccgat cagatcaggc
     5701 gttgtaaagc tgactttcat ccatactgca gtcagcacca tagatgctac cggttctaca
     5761 caggaaacga ggctggcttt tacagatcct atcatcttta cgcctgtcag atacagggaa
     5821 aatcccgcca tagttccaaa aagaataata aaggcaactg ctgcaaatgt ttccctgtca
     5881 aaaatcacct gataatccca tggacgaaat actgccataa gtactgctcc gccgatcagc
     5941 attccccatg ccagaaccag cggtgtagga aattgtgctt gcagtcttgc gggttttatt
     6001 gtatacacca ctacagaaac tgctgagagc agccccatgg ccagagcttt ctgagacaat
     6061 gccagagaag ttggattgcc atgagttgca atcagaaaga ttcctgttac tgcaagaaaa
     6121 actcccagca cctccttctt ttggggaagc cgttttgtcc gaaagcatac ccacacaacg
     6181 atcagtgcag gtccgagata ctgaatgacc gtagctgttc cggcattgga ccattcaata
     6241 gtctgaaaat agctgtactg acataacatc attcccgcca gaccataaac aataatatct
     6301 gtccggtttc tctttgtttt ccagatatca aatgtttttt cctttatctt tgaaaaaata
     6361 atagcacaga agaagaaggc ctgctgttac cagacgtatt ggaaccagcc aggctgctgt
     6421 tacctcttta ttctgaaaca ggaactgacc gcagacaccg gaaatccccc acaggattcc
     6481 tcccacgatt gtcagaaaag ttccaagcat catctctttt ttttggtttt gtttactttc
     6541 attgttcgtt tgcatatttc tgttatcttt cctgtctgta ttattatgga ttctgaatat
     6601 ttgagaataa gtataatctg ctgtaacgac acttgtcaag aaaacaaaat accgcagaga
     6661 ctttctttgt ctctgcggcg atttatagcc ctgttataat cagatataat ttccatcttg
     6721 tacactctgc actgtaaatg cagatttctt tttcacgaaa tcaatcgcat ctttcacagt
     6781 aattccgtca atctgccagt tcgcatagaa accatccaga gtctttaatg tctcgtcttt
     6841 tgctgtattt tcatcaagaa caagaagtac gatcagacct gctgccttaa gatggcggac
     6901 agtttctgca tagttttcac tcgctgccgg atgatacaga taggtatgtt ttccaagtac
     6961 agtcagtccc ttttctacct gctctgcaaa atcaagagtg attccttctt taccgatcgg
     7021 gaattccact actaccggtg tctgaccttt cagtcctgca cgaacctgct cgtccacttt
     7081 tccgatctgg gatctatcct gagaaacaaa ggtttttctc acaacaccgc aggcagaagt
     7141 catatttgtg acacgatctg tcaggatcag ctcacccagt gttctgtgcc tgtcaaattc
     7201 gtctacaacg atcttctctg agaattccag agtacaggaa gcaatctcat ttttctttaa
     7261 ggtatatgcg cttttctttt cacctgtatt aacatccaca gaataattga tctttgtaac
     7321 caggccgggg atcatctttg taccgatttt tacaaagaag ttcctgccat ccgtaagatc
     7381 attgtcatcc atccagagga tatctgcttc cacagagtct gtaagaactg cgccggaatc
     7441 aatggtaagt acacatccgc ggaaaacatc tacttctctg tcaagctgga tggtaacagg
     7501 ctgtccctgt accgcttcct gaacttcttt atcgccaaca agaatactct ttacatgagc
     7561 ttcttcttta ctgggaagag tagtcacaag gtcgcctgct ctgatgacac cattctcaat
     7621 ctgtccctgg aatccgcgaa actcatggtt tggtctgcag actctctgta caggcatata
     7681 gaagcccttc tctgtatctt ccttaatgtc tacggtttcc agatgagaaa gaagtgcctc
     7741 acctttatac catggcatgt tatcagattt ggttgtaacg ttgtcacctt ctgtggcaga
     7801 taccggaata atagttacat tggcaagttt cagttcttct atcagtgctg cgatctgatt
     7861 ctcaatgtcg cggaaacgtt tttcatcata ttcaataaga tccattttgt ttactgcaaa
     7921 tacaaagtaa cggattccca tcaatgcaca gattcttgca tggcgtcttg tctgtaccag
     7981 tactccctgt gaagcatcca ccaggataac tgccagatct gcaaaggacg cacccactgc
     8041 catgtttctt gtatattctt catgtccggg tgtatctgca acaatgaaac ttctgttatc
     8101 tgttgtaaaa taacgatatg caacatcaat ggtgattccc tgctcacgct ctgccatcag
     8161 accgtccaga acaagagaat aatcaatggc acctcctctg cttcctactt tggaatccag
     8221 ttccagagcc ttctcctgat ctgcatagag aagctttgca tcataaagaa tatgtccgat
     8281 cagagtggat tttccatcat ccacacttcc gcatgtaata aatttcaata atcctttcat
     8341 cctagaaata cccctctctt tcttctctcc atgctgcctg ctgcctcatg atcgatcacc
     8401 ctgctggtac gttcagaaga aacagcactt aacgtctcat caataatctc atccagagta
     8461 tctgcttcag attcaatacc accagtaagc ggatagcatc caagagtacg gaatctgact
     8521 tttttatttt caatcttttc acctggacgg agttttaatc tgtcatcatc caccataatg
     8581 atatttccat ctctgtagat gaccggtctt tcttttgcaa aatataacgg tacaatttcg
     8641 atattttcac gctgaatgta ctgccagata tccttttctg tccagttgga aattgggaat
     8701 actcgcatac tctctccctt ctggatctta gtgttgtaaa gcttccacat ctccggtctc
     8761 tggtttttcg gatcccatgc ctgagctgaa ttacggaaag agaagattct ttcttttgct
     8821 ctggatttct cctcatcacg acggccgcct ccaaatgccg ctgtaaatcc atatttggtc
     8881 agagcctgtt ttaacgcctg tgttttcatg atatctgtat atgcagaacc attgtcaaat
     8941 gggttgattc ctgcctttac accctcttca ttggtgtaaa ccagcatatc aattccgttt
     9001 tcctttgcaa ttctgtcgcg gaattcgatc atctcatgga atttccatgt agtatcaatg
     9061 tgaaggaacg ggaatggcgg tttctccggg taaaatgcct tcatcgccag atggagcata
     9121 acggagctgt cctttcctat agaatagagc ataaccggct tttcacactc ggctgctact
     9181 tcccgcataa tataaatcgc ctctgcctca ggcgcatcaa gatgagataa gttactcatt
     9241 gcattatcct cctctgtttg tttatactcg gaatcttttc gtacttgagc aaatacacta
     9301 gagcgtgtct gaaaaatcat tcccgcaatc tgcacgcccc actttgcggg agattttgtc
     9361 cgaattcggt tgtcgtagcc cgctacgacg ccctcatccg aacaaaatct cccacaaatt
     9421 gtgacgcaca tcttgcgtaa agcatttttc aaacacactc taaagactct gagaatacat
     9481 acttatgttt aatatttatt agcgtctttc ttattaacct gaatagtaat cttagtgcca
     9541 tccggcttct ccactgtcca tgtggaaata tccgttttct ctgatacaac catacttgca
     9601 cctctgcctc ctacatcggc tccaaggaag aagcggatgg catcatgcct gcattccttg
     9661 atacaggaag tacatcccca gcagtctctt acctgacgga taaaggcttt gttctcttta
     9721 tcctttttga tcagatttcc gggacaggct tcgatacatc tgccgcatcc cgcacattta
     9781 cttttctgaa tccgaatgct catctctcgc ctgctccttt ctctgcggta ttcaaacctg
     9841 tattttcctt tgtgatcaaa tcacgatata aaatcttaat ctcgccgttt tccatacggg
     9901 agtttacata tttcatccac tctttgctct gctgcgggta gtctgtgttc tctccgaaac
     9961 tatgccatct ggtttccttt ctggctgcca gatgtgcgat cactgcccgg cacacgatca
    10021 gtcgttcgcg cagttcataa atctgcatca gttcataagt atccgtcgct gccagagtgt
    10081 cagctacagg cagcaatgct gcaatctttt catctgcctt tgcaagactc atctcgctgt
    10141 atctgtagtc tgtaccgatt cctcctgcat actgatccat gatcttctgc atggcttcct
    10201 caagctgctc tgcattcatc aaagaacggg aagcattcaa atgtgattcg tattctgctt
    10261 tcttagctgt tgcagtttga gacagtttct gttcttcacc atgctccaaa gcctctttct
    10321 tattttccgc tgcgatccgg tcatcatctt tgccattcag atattccaaa atcgcctctg
    10381 ctgcgatctc accttctgcc agtgcgccgg ttacatattt ctgcggacat cctcctgcta
    10441 catctccggc tgcgtataaa ccttcaatag ttgtagctct gttattatct acccagtaac
    10501 cgctagctgt atgtccgcct acaatatatg gctctgtgcc ctcaatctct acattctctt
    10561 cggatggtcc ttttccggct tccatccatt tcagagtctg ggacggtgcc atattcaggt
    10621 aagctttgta aaggtcctgc tcctgttctt tggaaatacc ttccgttctg agataacatg
    10681 gaccgtttcc ttctctgttc tccatgactg taccgtaaac tcgctgggaa gttgtcagac
    10741 catattttgt ttcataaata tcaccatgtg cattgacctg tctggcccca acaccctgag
    10801 caatagttcc tgtaggagca atcgtgtcct tacatctcaa tgcaatgaaa cgcatctcaa
    10861 aggttgtcat ctccgcaccg gaaagaagtc ccattgcata tcctgcacct gtgttaaacg
    10921 gaggatacca catcttatgt ctggaaaatc ccggattatt cggtctgtaa agtcccgctg
    10981 caccacctgt ggcacaaaga actgctttcg catcaatgtc atagaaaata tcctcattaa
    11041 cgctaaatcc aactgcgcct gtgacttttt tgttttctgt tttataatct gtaatattta
    11101 catgattgag aaccgtaaca ttctcctgtt cagctgccgc ctttgcaagg attggcttca
    11161 tattttcgcc attgatcttg atgtttcggt ttcctctggc aacatatttt ccgttttcgt
    11221 ccttcaggat gaccagcccc agatcttcca tcacctttgt cacatgattc agtctctctg
    11281 acatggtaag aagaaggttt tctcttacga ttccatgggc atcctttttg gcataatcca
    11341 cataatcctg cggcgctctg ccttctgtaa tatatgcgtt caatgcattc acgcccgccg
    11401 ccagacatcc gcttcgctta atattcgctt tctctgcgat cagaactttt ctgccgcttt
    11461 ttttgccgat cacataggct gcaaagcatc ctgccgtacc gccgccgatg attagcacat
    11521 ctgtcctgat tctctctgtt ctcattctct cttacccttt cctccatacc agtgtgccaa
    11581 caagttgatt ttccgatcag tcttgcgtct gaatttctta tttcttcatt gtcgtcagtc
    11641 gccgcagcca ccgttgtcag ataattacaa agtcatccct tacagcctca ttttcgatca
    11701 gctgtacact gtcgcctctc agtgcaaaaa tcctgtaaag gaatacattc acagtctcgc
    11761 cttcccggat atctgctttc tccaggcttc ttctggcagt tactacggaa ttgttgactc
    11821 tcacctgaag ttccagatta tctcccctga aagaaacccg ttcaaccact ccccgggata
    11881 cggaagtttt gaacttctcc acctcatcca gtttggagat tttgacaaat tccggatgga
    11941 caatgatctt atctgctccc tctgcctgag caaaggtatg gaaatcatct gcgtttttca
    12001 acacagatgg ctgtccgaag aaggaagctg taaaagcagt ctccggattt ctgtaaaccc
    12061 ctataggagt tcctttctgt tcaatctgtc ctgcattggt gatgataatc tcatctgcta
    12121 cttcaatggc ttcatcctga tcatgagtaa cgaaaatact ggtaattccc agcttcccga
    12181 tcatctcctt taaccagctt cgcagttcct gacggatttt tgcatcaatg gctgcaaagg
    12241 gctcatccag aagcagcacc tggggatttg gagcaagggc tctggcaaac gccacccttt
    12301 gcctctgacc gccggataac tggcttggat atcttttttc cagtccttcc agtcccacca
    12361 gtttgatcag ttctctgact ctggtatcaa ttttcttctt gtctgccttc tgaaccttca
    12421 ggccaaatgc aacgttgtca taaaccgtca tatagcgaaa taacgcataa ttctgaaata
    12481 caaatccaat cccacgctgg ctggccggaa catcatttac cacttttcca tcaataataa
    12541 cttctccgct gtctggggtc tccagacctg cgatcattcg aagaatggta gtttttccgc
    12601 ttccgcttgg tcccagcaga ccgatcagct tacctttctc aattccgaaa ttcacattcc
    12661 ttgatgcctg gtaagaacca tatgtcttat tgatattttt taactctaca tacatatcag
    12721 gcttccttct ttcctttata ttcgatcagg cttctggcta ccagaatgat aaccgccatg
    12781 atcacaagca gcgaagatac ggcaaacgcc ggaacatact gaaattcatt aaacaaaatc
    12841 tctacatgaa gaggaagtgt attggtcttt cctcttaaat gtccggaaag tacagatacc
    12901 gctccaaact ctcccattgc tcttgccgta cagagcacaa ctccgtacag taatgcccat
    12961 ttgatatgag ggaatgtgat cttccagaaa atggtccatc cacctgctcc catcagggct
    13021 gccgcttcct cctcatcgct tccttctgct tccagaaccg ggatcagctc tctggaaata
    13081 aaaggaaagg ttacaaatac agttgcaata atgattcccg gtacagagaa tacaacttta
    13141 atccctaact tcatgagaaa aaagtaaaca ggactctgtc gtccaaaaat cagaagaaag
    13201 atcagacctg caataacagg ggaaatagta accggaaggt cgatcagtgt ggtaagaagc
    13261 tttttgcccc tgaactgaaa cttcgtcagt gcccaggctg caaaaacacc aaaaacagtg
    13321 ttaaaaacaa ctgcaaaaat tgttgccttc actgtaagaa gaagtgcttt gatggtgtac
    13381 tcatctgtca ctgcagctgc atagaccttc catccgctcc gcaatgcttc tgtgatcacg
    13441 gtgatcagag gaagaaggag catgactgcc agaaacagaa cgctgatccc gacaagcagc
    13501 cattttataa ttttcgccga agtcttttca ttgttgtcca tcaggcattt cctcctctta
    13561 aaattcttgc atttctctgc tgtatcatac tgttaaggaa cagaataaaa aatgaaactg
    13621 ccaacatcac aagtgcgatc gccgttgcac tggaataatc aaattcctga agctctgaca
    13681 taataaccag cggtgtgatt tctgtataat agggtttatt tcctgcgata aatacaacgc
    13741 ttccatattc acccagacat cttccgaacg caagtccggt ccctgcaaag atcgcgggct
    13801 tcagttccgg aaaaatgacc ttccagaaga tagttgtttt ctttgctccc agcactcctg
    13861 ctgcctcgct gtaagaatta tccatctttt ccagaaccgg ctgtacactt cgcacaacga
    13921 acggtatccc tacaaatatc atagccactg taataccgat tcttgtgtat gcgatcttga
    13981 tactgaatcc tgcaaaaaag ctgccgacaa ttccggaatc tgaagtcagg gatgtcagcg
    14041 caatacctgc taccgctgtg ggaagagcaa agggaagttc gatcatccca tccataagtc
    14101 tcttgcccgg aaaatcatat ttcacaagca cccacgcaag aatagttccc ataattccat
    14161 ttattactgc tgctgcaaaa gcacatacaa aactggtata aaaggatgcc agcactctgg
    14221 cccttgtgat ggtttcgata aaatctttaa aactcagctt cgctgtgtag accaccagac
    14281 ttgccagggg gatcagaact accagactca atatggaaat ggtaattccc atggagagtc
    14341 caaaccctgg aatcaccggt ttatttcttt ttttcataat caattaccac ctctcctgtc
    14401 tcatatattc tgtctgtgct tatgctcctg cttcatcttg tcttccttta tctctcataa
    14461 atctgatcga aaattccgcc atctgtgaaa tgtttcttct gcactttatc ccatccgcca
    14521 taatcactga tatttgccag atttatattc agatcaaacg tatcactgtg cttcttcaga
    14581 attttctcat tggtggggcg gaaataattc tctgctgcga tctcctgtgc ttcgtcggaa
    14641 tacagataat tcaaatactc agttgccaca tctcttgtat ctctgtaatc caccacttca
    14701 tctaccaccg ccacagaagg ctgtgccaga atgcttacgc ttggagtaac aatctcatac
    14761 tcatccggat aatcccgcat ggatagataa gcttcatttt cccacgcaac cagcacatct
    14821 ccttgtccgt tctccacgaa agaggtcgtt gcgcctcttg cgcctgagtc aagaaccacc
    14881 acattccgat aaagtttctt aataaattcc ttcatctgcg cttcatcgcc accatacttt
    14941 ttatctgcgt aagcccacgc tgccatgtag ttccatctgg caccgccgga ggttttcgga
    15001 tttggtgtta ctactcccac tccttttttc gtcagatcgt cccagtcttt gatatccctg
    15061 ggatttcctt tcttcaccag aaatacgata gtggatgtat aaggagaact gtcattgtca
    15121 aatttatctt tccatcctgc cttgatca
//
