LOCUS       c00018_gnlPro..        13073 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIBFGNFI_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:27:00
            Original ID  :: gnl|Prokka|KIBFGNFI_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13073
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13073
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[602:3073]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      603..3073
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13073
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13073
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             3..563
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="Arginase (E-value: 1.1e-50, bitscore:
                     164.1, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACV
                     LRRCHELVGDGRIHQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYL
                     TIDLDCLDPSCFPGTGTPEAGGVSFLQLLDAIRTVTKANIIGADLNELAPTLDTTGVST
                     ATACKVLRETLIALDKGWPGFQV"
     CDS             603..1862
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.1e-44, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 4.9e-33,
                     bitscore: 105.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTATKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWTTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHNPALVD"
     CDS             1862..3073
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.4e-14,
                     bitscore: 44.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEEQLHRLPTPCYLLDEAQLCRNGEILLG
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RADEFEELLQYADHIVFNSPSQLAKFGPAAKAAGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWDAAVAAHPELPTLLDGLHFHTLCEQDADALAVTLAAVEKKFADLLPRM
                     KWLNFGGGHHITRPGYALATLESCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     RNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGEKAHTVRLGGPTCLAGDIIGDY
                     SFDAPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGNCRELVHFGYQDFKMR
                     LGAQ"
     CDS             3341..3589
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MMKLLSCNFNMDTNRVEAKFADGVVLAIDCLAIEDEYGNTPAQRA
                     ELDWLLYNKPLEYAQLVLSGEIEHYLSLGCDHGRLED"
     CDS             3708..5057
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="LIDSNLITEYTNNSLFLIIFIKKANEFLEGCEIFMYCPNCGKENS
                     SEDRYCIYCGSELIDNQNFPETSEVDWKYVWQQIQSVTKSLCKKIQRFFKRHPKIAFPV
                     LAAVGCFLALSIANATVLSGESVARRYFKALMNNDSRAVYACLDLPESQFVNASEFDKF
                     FRSLGYQAHNIGDYEIKEYTTSSIESDITSNYYITYYVRGDSSTHSTSVEVVNVPLFFG
                     LINRYKVLSDYISSDFGVIVPAGSTVSVDGIILDGSTAYENYDRYSIPSLFCTGHDIAV
                     SNSLGSAEDSFVPSPGYGDSYTVYAVNYNADTVNAVYAQAQNQLNSILTAAIARQDFPA
                     DIVKSGDADNNVADRFSDLKSRLYDTSNNTGFTNIQVTATTDQSSQQVFDASTIQYNCT
                     MRFDYSYARRWQNYWSGETGIDNGTSYGQAAFTYVYEDGVWALESISFQM"
     CDS             5288..6055
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="VRQYNLCVMRSRIKGARAEGRLQLTNKRILFRAKGTAPVGETTIQ
                     HEFSIDEVAGFQIVRNFRFSILDLLLIFALSVAIGYIGVGFGGFLGRTLKAFGQLLVYV
                     LALAVAVPAFVWMPREQYAGKCVFLSASVGLFTVLREMIYFKSSFLTVLSQIFIYVPYL
                     IFGVLLAACVFAFAFKPNMEFLVRTKTGEAVIPIRCEKTGFAALGNVIDAQYMGYNEVL
                     PTDETEKAIREIGAIINDIQKLGDYGIAKWKTE"
     CDS             complement(6189..6383)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MDKGRFIKNPKSFLAGQGNKADRTGHFIDADIVSACLSAPIPNTA
                     IEDPHFRMVPCACDYFAGF"
     CDS             complement(6376..6885)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="VIKIPTNISVSILRIDKVSLSIALLCHENMSIKSTTIRSGPADIY
                     FHTGPIAVRCHCPFDCLAAAAGSFVDNRVFPCIKRVIRQAIRVIRVRQRADIIATFPQF
                     VGGHTVRAVSRPCKIGIVYLIMPVWIDFRKSLFHTFRKADSPKIFNSHMISTSFTSSKK
                     KSVTDG"
     CDS             complement(6866..7210)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="VPDFFPRPTWTVPLEVLWPDPDKNLYWHRDFPKIVFRWHAGSRSE
                     WKEALEPWTYRYPLPESLQNNYQSYFLPRHSLWHLPENLRNIQRFGRLVSGYRFEQNGS
                     LPAGRDQNTN"
     CDS             7502..7678
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MRPQIPPIRIADRVFLSGKEISLQSANPMDGSVEPRSRNLQLRQT
                     GSYMAELLKREKI"
     CDS             complement(7675..8037)
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MTIRICNFVIDHKSRGAVSGLSIHISDFRTVDRRSIFQGIRFAAL
                     HTPPSIAVHIVVLRDNIARVITSSKRRCLNMASLIARKVGARSGRHSFVISLCNFKIAI
                     GRYCSCVWINNSIVAS"
     CDS             complement(8161..8907)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="LFFVIDLIFIRRLAFGGLFGVLGILVLTVFFGVLRILVFAGFFGV
                     LRILVLTVLFGVLRILVLTVLFGVFGVLVFTVLFGVLGFLVLAILFGVLGFLVLAVLFS
                     VLGFLVLAVLFGVLGFLVLAVLFGILGILALTVLFGVLGFLVLAVLFGILGILALAGFF
                     SILGFLVLTVLFGVLGFLVLISFFGVLGLLSLTVIFCLVRLFILVIIFPCRGRQSTIIS
                     RCIFVSDIKVHLISFFHQSLIFFWRH"
     CDS             9170..9346
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="METVCLMLLMIKTMVFRVRIPRLLVARKLRQNQARKIMESVNNKE
                     AVASGTDEKNRSI"
     CDS             complement(9291..9698)
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="VLNFIIDIPVVRAVRTSSCTVIADNNISGRVEFPIKVSFRIEDYH
                     NIFRCEIVQQLIQQLIDRVRLTSTNTSQKHNVPAEQIFIQIDDLPCAASISTQSTFHRA
                     NRIGYWFIVKQSTIKYFYFFHQFHLQPPPYY"
     CDS             9700..9855
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MSIWKKISSKLQMRSSEKKSKKQISRSFQMQLKIFFQLYWRILST
                     TEKKTS"
     CDS             complement(9993..10358)
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="VCTSFTIDISDLLDILITNQKLDAQTTSKVNSVIHMTQIRQKTEL
                     VRDKIDASCTLFAAECFFDCQIKHQAVNGSQHRTNAQIILNKNAAPTFCTYKLTERKRS
                     FLFEVSDEHLPHGLLHL"
     CDS             10467..10616
                     /locus_tag="ctg18_17"
                     /transl_table=11
                     /translation="MSAVQGRGISEQIRDAYVVEDWDISRLGLGDAIVGLPGAEPFRFH
                     FARA"
     CDS             complement(10636..11067)
                     /locus_tag="ctg18_18"
                     /transl_table=11
                     /translation="LKERFCRGVLHFFGRKRRDIFRLRRFRGRCFRLNRKHRYRFQRRN
                     SNGLFRFRSNRFASSRCGGRLSRDFGLWLRNLPPRRNIFALFLGFTLLRLFRNTNSHRS
                     FGSFRFIRFKWPATFSTEFLFIQTCRSAAILTYFHNILP"
     CDS             11218..12720
                     /locus_tag="ctg18_19"
                     /transl_table=11
                     /translation="LLGGFFLWKKIALSKNATVGGISYSIADTASLSVESPSDEDWNNL
                     CRLSGLTSLTITGNIDLDARKLNELSTLQALTELSIDGAVFPDGLSSLASLSALESLSL
                     TNCQLSSSQCDGVSWPVSLRKLDLSGNGLTDISFLRNCTYLEELFLDENKIIDYTPVAA
                     LTGLTTLGVDQCQVQAVNSLPVLKKLLVNGQEIEEPAAYLAELSSMTESYQNIISLFEA
                     GDFDALTTVLQQLETAGSLDENVLTYANGWLMTNSSEWDIIRASLPSGSQMLVSDGNGL
                     YYGQMNNGKRFGNGIQLFAVNHSIYSGSWNNDLPNGMGTYRKTIADGTVLEFSGNYTDG
                     YENGTMTFTAASDSGTQSGSYTAVNGTRTTVEQISDNQVAFIRFDTIYWYDASPDGHGV
                     AIASIPYQEEKVIQISPKAEPAPSNSKNGSGNKNSSGAESTPPSAPQPSAPTESSSASS
                     STADSSNPWNMTPEDALKKIQDGVQTASDIYHAAKEIYDMFN"
ORIGIN
        1 gcggcgagca tctggtcacg ctgggcgccg tgcgggctgc ggtaaagaaa taccccgacc
       61 tgcacatcgt ccacttcgat gcccatgccg acctgcggga cgactatctg ggcgcgaagc
      121 tcagccacgc ctgtgtgctg cgccgctgcc acgagctggt aggggatggc cgtatccatc
      181 agttctgcat ccgcagcgga gaccgggcag agttcgagtt tgctgctcag cacaccgaga
      241 tgcacaagtt tgattttacc ggccttgccg agctgaccgc acagctgtgc gagagcaagg
      301 tgccggtgta cctgaccatc gatctggact gccttgaccc ctcctgcttc ccgggtaccg
      361 gtaccccgga agctggcggc gtaagctttt tgcagctgct ggatgccatc cgcactgtga
      421 ccaaggccaa catcatcggt gcagacctga acgagctggc ccccacactg gacaccaccg
      481 gcgtttccac cgccaccgcc tgcaaggtgc tgcgcgagac cctgatcgcg ctggacaagg
      541 gctggccggg ctttcaggta taaatacgaa cctaccattt tacagataaa ggagtaaccg
      601 acatgagcaa agttctgatc atcggctgcg gcggcgtggc ctctgttgcc atccataagt
      661 gctgccaggt gcccgaggtg ttcaccgaga tctgcatcgc cagccgtacc aaggcaaagt
      721 gcgataagct ggctgctgag ctggctccca ccaccgccac caagatcacc accgcacagg
      781 tggacgcaga caaggtggag gaggtcatcg ccctcatcaa ggcttaccag cccgacctcg
      841 tgatgaacat cgccctgcct tatcaggatc tgaccatcat ggacgcctgc cttgcctgcg
      901 gcgtcaacta catggacacc gccaactacg agcccgagaa caccgacgac ccggagtggc
      961 gcgccatcta cgagaagcgc tgcaaggagg ccggcttctc tgcctacttc gattacagct
     1021 ggcagtgggc ctacgccaaa aagttcgagg aagccggtct gaccgccctg ctgggcagcg
     1081 gcttcgaccc gggtgtgacc caggcttact gtgcctacgc caaaaagcac gagtttgata
     1141 ccattgacac catcgatatt ctggactgca acggcggcga ccacggctat gcctttgcca
     1201 ccaactttaa cccggaaatc aacctgcgcg aggtgtccgc acccggcagc tactgggaga
     1261 acggccactg ggtagagatc ccggccatga gcatcaagcg ggagtacaac ttcgatcagg
     1321 tgggcgacaa ggatatgtac ctgctgcacc acgaggagat cgagtctctg gcaaagaaca
     1381 tcccggaggc aaagcgcatc cgcttcttca tgacctttgg ccagagctat ctggaccaca
     1441 tgcgctgtct ggaggacgtg ggcatgctgt ccaccacccc tgtcaacttc aacggacagg
     1501 agatcgtgcc catccagttc ctcaaggctc tgctgccgga ccccgccagc cttggccccc
     1561 gcactaaggg caagaccaac atcggctgca tctttaccgg caaaaaggac ggtaaggata
     1621 agacctacta catctacaac gtctgtgacc atcaggagtg ctacaaggaa gtgggcagtc
     1681 aggccatcag ctacaccacc ggcgtgcccg ccatgtgtgg tgcactgatg ctgctcaccg
     1741 gcaagtggac caccaagggc gtgcacactg tcgaggagtt tgatcccgat ccgtatctgg
     1801 atgcactgga taagtacggc ctgccccgct ccgagagcca taacccggct ctggtggact
     1861 gatgcgggtg cgcgacagcc gcccgccctt tgcggggctg gcaaacctgt ccgaggagca
     1921 gctgcaccgc ctgcccaccc cctgctatct gctggacgaa gcccaactgt gccgcaacgg
     1981 tgagatcctg ctgggcgtgc agcagcgcac cggctgccgc atcctgctgg cgcagaaggc
     2041 tttttccaac ttcaatgtct acccggtgct ggcaccctat ctggcaggta ccgaggccag
     2101 cggcctgtac gagagtcgct tgggcaggga agagctgccg gagaaggaga accatgtgtt
     2161 ctgcgccgcc taccgggcag atgagtttga ggaattgctg caatacgccg accacatcgt
     2221 gttcaactcg cccagccagc tggcaaagtt cggcccggcg gcaaaggcag cgggcaaaag
     2281 catcggtctg cgcatcaacc cggagtgctc cacgcaggag ggtcacgaaa tttacgaccc
     2341 ctgcgccccc ggcagccgtc tgggcaccac ccgtgctcag tgggatgccg ctgtggcggc
     2401 gcacccggag ctgcctaccc tgctggacgg tctgcacttc cataccctct gcgagcagga
     2461 cgcggacgcg ctggcggtaa cgctggccgc agtggagaaa aagtttgcag acctgctgcc
     2521 cagaatgaag tggctcaact tcggcggggg gcaccacatc acccgcccgg gctatgccct
     2581 tgctacgctg gaaagctgca tcctctcggt gcggcagaag tacggcgtac aggtgtatct
     2641 ggagcccggc gaggcttggg cgctgaacgc gggatatctc gtcaccaccg tgctggacac
     2701 cctgcgcaac ggggatacca gccttgccat tctggatatg tccgcagcct gccacacccc
     2761 ggatgtcatc gagatgccct accgcccgcc gctgctggac gccggtgagg caggggagaa
     2821 ggcgcacacc gtccggctgg gcggccccac ctgccttgcg ggggatatca tcggggatta
     2881 cagctttgac gccccccttg ccgagggcga taagctcatt ttcggcgata tggccatcta
     2941 caccacctgc aagaacaaca ccttcaatgg gatgcccctg ccgcccatct ggctgctggg
     3001 cgcagacggc aattgcaggg aactggtgca ctttggctat caggacttca aaatgcgctt
     3061 gggcgcacag taaaataaaa agcgtttgtc acggcctgcg ggctgcgaca aacgcttttt
     3121 tcatgaaagg ggacgtaagg tgaacggcag ataaaacaaa aaagcaccac acgtttccgt
     3181 gtagtgcttt cattctggtg gagattaccg ggatcgaacc ggtgacctct tgcatgccat
     3241 gcaagcgctc tcccgaacca tgcggttaca caccccacac aaagctgtgg ggatggatgg
     3301 cgattcacgt taaaacaatg gatttcagga gaaaatggca atgatgaaac ttttgagctg
     3361 taattttaac atggatacca accgggtaga ggcaaaattt gcagatggcg ttgtgcttgc
     3421 catcgactgc cttgccattg aggacgaata cggcaatacc cctgcacagc gggcagaact
     3481 ggactggctg ctgtacaaca aacctctgga gtatgcacag cttgtgctga gtggcgagat
     3541 agaacactac ctctcccttg gctgcgacca tggcaggctg gaagattaag attcccataa
     3601 agaacacgat gcctaccggt ttgtggattt ccgtaaacca gtgggcatcg ttctggcatc
     3661 agagtaatgg agccgtatag gagaaaagac aattatattt ttaatttttg attgacagca
     3721 atcttattac agagtatact aacaatagtt tgtttctcat aattttcatc aagaaagcaa
     3781 acgaattttt agaaggatgt gagattttca tgtattgtcc aaattgcggc aaggaaaatt
     3841 cctcggaaga caggtactgt atctattgcg gctcagaatt gattgacaac cagaattttc
     3901 cagaaacttc tgaagtcgat tggaaatatg tgtggcaaca gattcagagc gttaccaaat
     3961 ccctctgcaa aaagatccag cgttttttca agcgtcatcc taaaatcgcg ttccctgttt
     4021 tggcagccgt tggttgcttt ttggctctgt ccattgcaaa tgcgaccgtt ctttccggag
     4081 aaagtgttgc ccggagatat tttaaggcgt tgatgaataa cgacagccgt gctgtatatg
     4141 cttgcctgga tcttccggaa agccagtttg taaatgcgtc cgaatttgat aagttcttcc
     4201 ggtctctggg atatcaggct cataatattg gtgattatga gattaaggag tatactactt
     4261 cttccataga atctgatatc acatcaaatt actatatcac ctattatgtg cgaggggact
     4321 cttctacgca cagcacctct gtagaggtcg tcaatgttcc tcttttcttt ggtcttatca
     4381 accgttataa agttctttcg gactatattt cctctgattt cggagtgatt gttccggcag
     4441 gctcgacagt ctctgtcgat ggcattatcc tagacggttc gacagcttat gaaaattacg
     4501 accgctattc tattccatcg ttgttctgta cggggcatga tatcgcagtg tcaaactctc
     4561 ttggctccgc agaagacagc tttgtccctt cgccggggta cggagacagc tatacggtct
     4621 atgctgtaaa ctacaatgca gatacagtga atgctgtcta tgcacaggcg cagaaccagc
     4681 tgaattctat tcttacagcg gcaatcgctc ggcaggattt ccctgctgat atcgtaaagt
     4741 ccggtgacgc tgacaacaat gtggcagacc gtttctctga tttgaaatcc cgtctttatg
     4801 atacgagcaa caatactggc tttacaaata ttcaggtcac tgctaccact gatcaatcct
     4861 ctcagcaggt gtttgatgca tctacgatcc agtataactg tactatgagg tttgattatt
     4921 cttatgcgcg ccgttggcag aattactgga gcggtgagac tggaatagat aatggcacca
     4981 gctatggtca ggcagcgttt acttatgtgt atgaagatgg agtatgggca ctggaaagca
     5041 tcagcttcca gatgtaaaag ttaaaggagt gttgatcatg ccttattgta caagatgcgg
     5101 aaaacccatt caggagggtg aacggtgcag ctgcacgaaa aaaaatggcc taaatttcaa
     5161 attctcttct gattccacag cgggttccct ttcctttggt tctgctggcc ggaatccgga
     5221 tgttcagtat gagcgcggac agaaaattgt gccggataat attgctccta atgagagtga
     5281 aattccggtg cgccagtata atttgtgtgt catgcgttct cgaatcaagg gtgcccgagc
     5341 agagggacgt ctgcagctaa cgaataagcg aattcttttt cgggcaaaag gaacagctcc
     5401 agtaggagaa acaacgatcc agcatgagtt ctccattgat gaagttgccg gtttccagat
     5461 tgtacgcaat tttcgcttca gcattctgga tcttctgcta atttttgcgc tcagtgttgc
     5521 aatcggttat atcggagttg gttttggcgg ttttctgggc agaacactga aagcgtttgg
     5581 tcagcttctc gtctatgttc tggctcttgc tgtggctgtg cctgcgtttg tatggatgcc
     5641 gcgggaacag tatgctggca aatgtgtttt cctgtccgcc agtgtaggtt tgtttactgt
     5701 gttaagagaa atgatttatt tcaagagcag ctttctgact gttcttagcc aaatctttat
     5761 ctatgtcccc tatcttattt ttggtgtcct gctggccgcc tgtgtctttg cgtttgcgtt
     5821 caaaccgaac atggagtttc ttgtccgcac caaaacaggc gaggccgtta ttcccatccg
     5881 ctgcgaaaag actggttttg ctgcgcttgg caatgtcatc gatgcgcagt atatgggata
     5941 taacgaggtt ctgcctactg acgagacaga aaaagcaatc cgcgaaattg gtgccatcat
     6001 caatgatatc caaaaacttg gtgattatgg cattgccaaa tggaaaacgg agtgactttt
     6061 gtctgtctgt gtaaaaaaag attattatct gatttttaag ggtctctttg caagaagaga
     6121 cccatttttg acaggagatt tctatggtca agtttgaaga agggcttgcg gttgcaaaaa
     6181 atcactattc aaaaaccggc gaaatagtca caggcgcatg gaaccatccg gaaatgtgga
     6241 tcttctatgg ctgtattggg gatgggcgca gaaaggcagg cggacactat atctgcatca
     6301 ataaaatgac cggtgcggtc agctttattt ccctgcccag caaggaagga tttaggattc
     6361 ttgatgaagc ggcctttatc catccgtgac gcttttcttt ttggaactgg taaaggatgt
     6421 tgatatcata tgagaattga agatcttggg cgagtccgct ttccggaaag tatggaagag
     6481 gctctttcta aaatcaatcc aaacgggcat gatgaggtaa acgatgccaa ttttgcatgg
     6541 tctggaaact gcacgcactg tgtgcccgcc tacgaactgc ggaaacgtgg ctatgatgtc
     6601 agcgcgttgc cgtacacgga tgacccgaat ggcctgtctt atgacccgtt tgatgcatgg
     6661 gaagacccta ttatccacaa aactcccggc agcggccgcg aggcaatcga acgggcaatg
     6721 gcatcttacg gcgatggggc ccgtgtggaa atagatgtcg gctgggccac ttctgatggt
     6781 agtggatttg atggacatgt tttcgtggca gagcagcgcg atggaaagac ttactttatc
     6841 gatcctcaaa atggagacgc tgatgttagt tggtattttg atcacgtcca gccgggagcg
     6901 acccgttttg ctcgaatcga taacctgaca ccaagcgacc gaatcgctga atgttgcgca
     6961 aattctcagg caaatgccat aaactatgac gcggcaggaa ataagattgg taattgttct
     7021 gcaacgattc cggcagagga tatcgatatg tccacggctc gagggcttcc ttccactcac
     7081 ttctggaacc ggcgtgccag cgaaaaacaa ttttgggaaa atcacggtgc caataaagat
     7141 ttttatctgg atcaggccag aggacttcca gcggtacagt ccatgttggc cgagggaaaa
     7201 agtccggcac agatccgagc ggagcaccct aatctaggaa acacactgga tgcgtactat
     7261 aatccaaaca atatgattca ggtcaatcgg gacgcaaacg gaaatatgtc ctttttggat
     7321 gacggtaaac atcgtgtcct tgcggcaaag gagctgggac tgaaagtgcc tgtccagatc
     7381 gccaatgatc aggcacccag caacgtgcag tctgccgcgc ctgtaggcaa gtcggcagcg
     7441 cagattcggg gagaacgttt tcaggatagt cttttgtcat tcccttctca gacagcctcc
     7501 aatgcggcct caaattccgc cgattcggat agccgaccgg gtgttcctga gcgggaaaga
     7561 gatatcgttg cagagcgcca atccgatgga tgggagcgtg gagccgcgct ccagaaacct
     7621 acagcttcgg caaacaggga gttacatggc agaacttctg aaacgggaga aaatttaaga
     7681 ggcaactata ctgttgttga tccaaacaca ggaacagtaa cgtccaatgg caatcttgaa
     7741 attacaaagg gaaatcacaa aggaatgcct tcccgaacga gcgcctacct tcctggcgat
     7801 gagcgaggcc atattcaggc atcttctctt ggaggaagta atgaccctag caatattgtc
     7861 cctcagcacc acgatgtgaa ccgctatgga tggcggggta tggagcgcgg cgaaacggat
     7921 gccttgaaaa atggagcgtc tatcgacagt acgaaaatcg cttatgtgga tggaaagtcc
     7981 ggagaccgcc cctcggcttt tatggtcaat gacaaaatta catatccgga tggtcatacc
     8041 gaaaatgttc atctttcttt ttcaaacgaa agttacgccg atcaagcgga ggaggaacga
     8101 atcgttgcct ctctgggaga tgaaatctat gatgccccta atccggatgc tgccagagaa
     8161 tcaatgtcgc cagaagaata taaggctctg atggaagaag ctgatcaagt ggactttgat
     8221 atccgagacg aatatgcacc tgctgattat agtggattgc ctccctcggc aagggaagat
     8281 aataacgagg ataaaaagtc tgaccagaca gaagatgacc gtaagcgaga ggagtccgag
     8341 gacaccgaag aagctgatga ggacgaggaa cccgaggacg ccgaagagaa cggtgagaac
     8401 gaggaacccg aggatgctga agaaaccggc gagggcgaga atcccgagga tgccgaagag
     8461 aacggcgagg acgaggaatc cgaggacacc gaagagaacg gtgagggcga gaatcccgag
     8521 gatgccgaag agaacggcga ggacgaggaa tccgaggaca ccgaagagaa cggcgaggac
     8581 gaggaatccg aggacactga agagaacggc gaggacgagg aatccgagga caccgaagag
     8641 aatggcgagg acgaggaatc cgaggacacc gaagagaacg gtgaagacga gaaccccgaa
     8701 gacaccgaag agaacggtga ggacgagaat cctaaggaca ccgaagagaa cggtgaggac
     8761 gagaatccta aggacgccga agaaaccggc gaagacgaga atcctgagga cgccgaagaa
     8821 aacggtgagg acgagaatcc cgaggacgcc gaagaggcca ccgaaggcaa ggcgtctgat
     8881 aaagatcaaa tcgatgacga agaacaagac cctgacgatg atgaaacaga cgacaaaaac
     8941 agagaggatg aaaacggaat cgaagatgca gatgacccgc aggatgaaga gaatgagtcc
     9001 aacggaatcg aagacggctc ttccgatgat gatgcggcgg cgatgagtgc ggaagaaaat
     9061 ggcatctctg atacgcccga ggattctccc tctcaagcca gcgataacgg catttcggat
     9121 gacgattcag gtcaaactcc agcttccaaa gaggacaacg ggatttccga tggagacagt
     9181 gtgcctgatg cttctaatga tcaagacaat ggtatttcgg gtgaggatcc cgcgtcttct
     9241 ggtagcgcgg aagctccggc agaatcaagc tcgcaagata atggaatcag tcaataataa
     9301 ggaggcggtt gcaagtggaa ctgatgaaaa aaatagaagt atttgatggt cgattgcttc
     9361 acgataaacc agtaccctat ccggttggcc ctgtgaaatg tactttgcgt ggagatggaa
     9421 gcagcgcagg gcaagtcatc aatttggatg aaaatctgct cagccggcac attatgcttc
     9481 tgggaggtat tggtactggt aagacgaaca cgatcaatca gctgctgaat caactgctga
     9541 acaatctcac aacggaagat attgtgataa tcttcgatac gaaaggagac ttttatcggg
     9601 aattctactc gcccggagat gttgttatca gcaatgacgg tacagctact ggtccgaacg
     9661 gcccggacta ctggaatatc tataatgaaa ttgagcacga tgagcatatg gaagaaaata
     9721 tcatcgaaat tgcaaatgcg ctcttccgag aaaaaatcga aaaaacaaat cagccgttct
     9781 ttccaaatgc agctaaagat attttttcag ctgtattggc gcattttatc gactacggaa
     9841 aagaagacct catgaacaat gaacatctca aagattttct ggacagcaca ccgtcttctg
     9901 acctgcgcag gttgctgaat atgcgtaagt ctacacgatc tatggtaagt tatattgcgg
     9961 acgattcttc tgcacagacg cagggcgttt tgtcagagat gcagcaggcc gtgcgggaga
    10021 tgttcatcgg aaacttcaaa aagaaaggaa cgctttctct ccgtcagctt gtacgtgcaa
    10081 aaggtgggcg ctgcgttttt attgagtatg atttgggcat tggttctatg ctggctccca
    10141 tttacagcct gatgtttgat ttggcaatca aagaagcact ctgccgcaaa aagagtgcag
    10201 gaagcgtcta ttttatcacg gacgagttca gtcttctgcc taatctgcgt catgtggatg
    10261 acgctgttaa ctttggacgt agtttgggca tcaagtttct gattggttat cagaatatcg
    10321 agcagatcgc tgatatctat ggtgaagctc gtgcacacag tctgctatct ggtttcctga
    10381 cgggcatctt ttttcgatgc aacgatgcag gttctgtccg gtatattaaa gaattctttg
    10441 gacagaaccg aaagaaagag gtgtttatgt cagcggtgca gggacgcggc atctctgaac
    10501 agatacggga tgcctacgtt gtagaagact gggatatttc gcgtctgggg ttaggcgatg
    10561 ccattgttgg gctccccggt gcggaaccgt tccgattcca ttttgcacga gcctgaatca
    10621 tacggaaggt tatttttaag gaagtatgtt atgaaagtat gtcaatattg cggcacttct
    10681 gcacgtttgg atgaacaaaa attctgtgct aaatgtggca ggccatttga aacgaatgaa
    10741 tctgaagctc ccgaaactcc tgtgagagtt cgtgttccga aacagcctca ggagagtaaa
    10801 accgaggaaa agagcgaaaa tgttcctgcg cggaggaagg ttgcggagcc aaagcccgaa
    10861 gtcccggctg agcctgccgc cgcacctgct cgacgcaaaa cggttcgacc tgaaccgaaa
    10921 aagcccgttg gaattccgcc tctggaacct ataccggtgc ttcctgttca gcctgaaaca
    10981 ccggcctcga aatcttctca gcctgaaaat atcccgtcgc ttcctgccga agaagtgcag
    11041 aacgccccgg cagaatcttt ctttcaaaca cgaccggaac ccgaggcttc atccgagact
    11101 ttaccggata ctccggctga tttggtggat gccgtttcgg aaatgccgat ttctcagtca
    11161 aaaaaaggcc caccaaaggt ttttctggtt ctgcttgtta ttatctttgc agctgcattg
    11221 ctcggcggct ttttcctctg gaaaaaaatc gcgctgagca aaaatgcgac cgttggaggc
    11281 atttcttata gcattgcaga taccgccagt ctttccgttg aatctccttc ggatgaagat
    11341 tggaacaacc tgtgcaggtt gtctggtctg accagtctaa cgattactgg aaatatcgat
    11401 ttggacgcca gaaagctgaa tgaattgagc acgctgcagg cgttgacgga gctttctatt
    11461 gacggtgctg tttttccgga cgggctttct tcgctggcgt ccctttcagc gttggaatcc
    11521 ctctccctga caaactgtca gttgagcagc agccagtgcg atggtgtgag ctggcccgtc
    11581 tctcttcgca aattggacct ttcggggaat ggcctgaccg atatttcttt cctccgaaat
    11641 tgtacatatc tggaagagct ttttttggac gaaaataaaa tcattgatta tactcctgtt
    11701 gccgctttga ccggtctgac gacacttggc gtagaccaat gtcaggttca ggcggttaac
    11761 agcttgcctg tgctgaaaaa gttgctcgta aatggtcagg aaatcgagga acccgcagca
    11821 tatctggcgg agctgagttc gatgacagag tcgtatcaga acattatcag tctgttcgag
    11881 gctggtgact tcgatgcgct aacgactgta ttacagcagc tcgagactgc tggttctctg
    11941 gatgaaaatg tattgactta cgcaaatggt tggctgatga ccaatagctc agaatgggat
    12001 attatccggg caagtctgcc gagcggttcg cagatgcttg tatccgatgg caacggtctc
    12061 tattatggtc agatgaacaa cggaaagcgt tttggaaacg gcattcagct gtttgccgta
    12121 aatcatagta tttacagtgg ctcgtggaat aatgatcttc ccaacggcat gggtacttac
    12181 cgtaaaacaa ttgcagacgg aaccgttctt gaattttctg gcaactatac ggatggctat
    12241 gagaatggta ctatgacttt cacagccgca agtgattcag ggactcagtc tggtagctac
    12301 actgctgtta acggaactcg cacgacggtg gagcagatta gcgataatca ggttgcattt
    12361 atccggttcg acacgattta ctggtacgac gcttctcctg acggccacgg tgtagcgatt
    12421 gcttccattc cgtatcagga agagaaggtt attcaaattt cgccaaaagc agaacctgct
    12481 ccttcgaata gcaaaaatgg ctccggtaac aagaactcca gcggagcaga aagcacgccc
    12541 ccttctgcac ctcaacccag tgcgccgacc gaaagctctt ctgcaagcag ttcaaccgca
    12601 gatagctcga atccatggaa catgaccccg gaagatgctt tgaaaaaaat tcaggatggt
    12661 gtacaaactg cttctgatat ctaccatgca gcaaaagaaa tctatgatat gttcaactaa
    12721 tcctgtggag aaatttcagg agaataaatt atgaaaatat gtgcttattg tcacacgcct
    12781 gcgcgatttg aaaatcagag attctgctct gtatgtggca aatcttttga ctctgaaaaa
    12841 gaatctcatg agaataacac ggcatcaccg gagcctcccg cagaagagcc tgtccctgca
    12901 acacctgtcc ggaggcagca acatccaaca cctgtagaaa tgccaaaact gtcgttagat
    12961 ctcgagccta ccaaagaaac aaatacgccc acccagagcg tttgtgaaga ggggcaatct
    13021 ccggaagtag tacgtcagcc aactcgtaat atgcctgcat atactccccc ttc
//
