LOCUS       c00008_gnlPro..        17283 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LKKGCLKG_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 20:55:16
            Original ID  :: gnl|Prokka|LKKGCLKG_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17283
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17283
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5220:8215]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5221..8215
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17283
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17283
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(148..1560)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MKNMTLERITEVCGGVYYGSEADKKKEIAGAVIDSRQVESGYLFI
                     AVKGEKVDGHQFIPQVFEKGALAVLSEQELSDPAGPYIRVESTLGAMKKLAAYYRRSLD
                     IKVVGITGSVGKTSTKEMIASVLSQKYNVLKTEGNFNNEIGLPLTIFKIREQHEVAVLE
                     MGISEFGEMHRLAEMAYPDICVITNIGLCHLENLLTRDGILKAKTESFEHLTPEGTAVL
                     NGDDDKLCEKKMVNGKPVVFYGIGKEAKPAKTERGEKYLAEKEVYATDVEPVGLDGTKA
                     VIHIGAESFAVTIPIAGEHNVYNALAAVCVAGKLGLSVDEMKRGIESVKTIGGRSNLIH
                     KGGMTIIDDCYNANPVSMKASIDVLAAAPGRKIAVLGDMGELGENEQELHAMVGEHFEG
                     KGIDALFAAGALSENLAQAVGKCSKETEVHYFKTKDELMEELLPYVKSGDTVLVKASHF
                     MGFTEVVGQLTK"
     CDS             complement(1616..2671)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.6e-54,
                     bitscore: 174.6, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 5.9e-27,
                     bitscore: 84.3, seeds: 635, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVVLAGGLSTERDVSFKTGDMVAKALRENGHQVILLDVFMGYS
                     DKKEDLTGIFDRSEEVSVKVSGIPETAPDLAKVKASRKDQSDNFFGPNVIELCQMSDIV
                     FMALHGENGENGKIQAAFDLFGIRYTGTGYLSSALAMDKEMSKKLFLSAGIPAPKGASM
                     KKADRSDDITKLGIQFPCVVKPCCGGSSIGVSIAHNAEEYKAALDEAFRWEENLIVEEY
                     VKGREFSVGVIEGKALPIIEIAPVQGFYDYKNKYKAGSAVETCPAELSEAVTEKMQHYA
                     EQVAQVLGLDTYSRTDFLLDEKENIYCLEANTLPGMTPTSLLPQEAQVVGVNFNELCEK
                     LIQISLDKYEK"
     CDS             complement(2932..3237)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="VENYITEQKKAEEMYNGAEILVDLARRYPELWNEIDRQCTLNRER
                     YGLLCEILLAGDEERCEDVVAKIYRYGSMIGKQDLIGRQIFLWLLQALRMEEIAML"
     CDS             3420..4268
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MSVRIIVDSASDLTKERADALNLDYMPLKTIFGETEYLDGVTISH
                     KEFYEKLIECGTIPTTSQVSPHDFEAKFKEVKEAGDTAVVICLSSLLSGTYQSAHIALD
                     GYEDCITLVDSLNVCLGEQILVLYAVKLRDEGLSAKEIAEKLEEKKKDVCVLAVFDTLE
                     YLKQGGRISKTAAWAGNILSIKPVIAIEKGEVAILGKARGSKNGNNILIQEVKNKNGID
                     FSMPYMLGYSGLDDSLLRKYIADSADLWTGQTKELPISTIGSTIGTHAGPGAICVSFFH
                     K"
     CDS             complement(4475..5005)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MRIKITGRNIELTDGIKDAVEDKLNKLEKYFTPDTDVYVTLSVEK
                     ERQKVEVTIPMKGNYIRSEQVSNDMYVSIDLVEEVIERQLKKYRTKLVTKQQSAASVFK
                     QDFLDAASDDDEEIKIIRSKKFDMKPMYPEDACVQMELLGHDFFVFINAETEDVNVVYK
                     RKGNTYGLIEPEY"
     CDS             complement(5081..5221)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MASHYDIASLVKCVILIVPANDAHFYKNITGKYKYSEKYIKNDIL
                     Y"
     CDS             complement(5221..5970)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 80.6;
                     E-value: 4.4e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="Radical_SAM (E-value: 3.2e-33, bitscore:
                     105.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYIHSLESFGTVDGPGVRFVVFFEGCPMRCQYCHNPDTWVLTDG
                     KQMEADEIIDRFLRNASFYRTGGITATGGEPMLQIDFLTELFAKAKAHGIHTCLDTSGI
                     MFPGFPEDGEATSDITLEKIDRLLDVTDLVMLDIKHIRDEDHRKLTGHSNKNILAFARY
                     LDQKKKPVWIRHVVVPGITFEEAELTELGHFLKTLSNMEKLEVLPYHALGKVKYDNLGM
                     DYVLKDTPQLTKEEAKKAEQMIRDAMS"
     CDS             complement(5987..8215)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="Gly_radical (E-value: 2.2e-46, bitscore:
                     147.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.9e-281, bitscore:
                     923.4, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNEWRDFNGGAWENEVNVRDFIQRNYKPYDGDSSFLEGPTEDTT
                     ALWQDVLELSKQEREAGGVLDMDTKIISTITSHGPAYLDKDKEKIVGFQTDKPFKRSLQ
                     PYGGIRMAIKACEDNGYKVDPEVVEYFTTHRKTHNAGVFDAYTPEMRACRSAHIITGLP
                     DAYGRGRIIGDYRRPALYGVDRLIEDKQEQLDSTRTIMYSDVIREREELSEQIRALKML
                     KELAKIYGCDISKPATNVLEAAQAVYFAYLAAVKEQNGAAMSLGRTSTFLDIYAERDLR
                     EGTFTEKEIQEIIDQFIMKLRCVKFARTPEYNSIFAGDPTWVTESIAGIGVDGRHMVTK
                     MSYRYLNTLNNIGAAPEPNLTVLWSVKLPENFKKFCAEISIKHSAIQYENDDIMRVVHG
                     DDYGIACCVSSMRIGKEMQFFGARANLAKCLLYAINGGVDEISGKQVGPKYRPITSEYL
                     DYDEVWDKYKDMMKWLASVYVNALNIIHYMHDKYCYERMQMALHDKQVRRWFATGIAGF
                     SVVADSLSAIKYAKVKPIRDENGITVDFEIEGDFPKYGNDDDRVDEIAKEVLHTFIKYV
                     KGNHTYRGGIATTSILTITSNVSYGKNTGATPDGRKKGVAFAPGANPMHGRDKNGAVAS
                     LASVAKMPFMDAQDGISNTFTIVPDALGKTEESSETNLVALLDGYAEKGGHHLNVNVLN
                     KETLLDAQKHPEEYPQLTIRVSGYAVNFIKLTKEQQDEVIARTFHELM"
     CDS             complement(8607..9539)
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MESSVLEEKVFHKVMKNVPFGLVVSSEGRKRKVYYVNTMAYHMLG
                     YTREEFIEKVQDGWSRFVDIDLRMVMREHHEEILTGESFELTAQTETKDGNKKWLSFRV
                     MVSMDVISSQLKPVSYITITDVTEKVEKNRRYAREREYLRDCAARDSMTRLLNRGTMED
                     RIKEELESVAEGQNYAYIAIDLDNFKQVNDVYGHWVGDRVIMSVSNILREVYGNQVSIG
                     RMGGDEFAVFLPDVKDRMWIQGQADEVLYRLRRQKEMIGMAEEPTASIGIAFGPEDGTS
                     FRELYHRADAALYQVKKEEKNSIAIYTMI"
     CDS             9745..10191
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MKIGIISDTHGIFREEWHRHLDGCDYLIHAGDFCTQKNYDCFRNF
                     GIPLYMVRGNNDRGDWAKNLPEFLQFRIGGKTFFLVHNQFDLPFDLTDADFLIFGHTHH
                     YTFYKRFNKVYINPGSASDGRGDSKSLAILTLSGNDYSLERVIL"
     CDS             10223..11149
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="LLHITSLNEGLELFKALGSDVRIEILNILLENDNMSMNELASRLN
                     ITNGALTSHIKKLENCGLITTSSESAVHGNQKICSIHLDKILIDLEKPAEIENVYHTEL
                     KVGHYTNYQICPTCGLASADALIGEVDDPRYFEHPDRYNADILWFTRGYVEYAIPNFIP
                     ASKKITQITISAELSSEAPGTNNDWPSDISFYLNDIHIGDWTSPGDFGDVKGLLTPDWW
                     YANWNQYGLLKQLVINQKGTYIDGLKISDVKIDDFHLNCHSSIRFRLAVEDDARHVGGL
                     TIFGKSFGNYSQDIKVSLGYAPVEEMK"
     CDS             complement(11190..11432)
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MAQICKKCLLREMAEADAKMIEKYKEAIKKEDQVSESEYERRLTV
                     CKTCELLNAGTCGACGCYVELRAAAAVSKCPYKKW"
     CDS             complement(11522..13027)
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MAKLIINEENKKSRIEPEIYGHFSEHLGRCIYEGIYVGEKSEIPN
                     VNGMRTDVVDALKELKVPVLRWPGGCFADEYHWMDGIGPKEKRKKMINTHWGGVVEDNS
                     FGTHEYMELCRQIGCKTYVNGNLGSGTVREMSEWVEYMTFEGVSPMADLRKENGHEAPW
                     KVDYFGVGNENWGCGGNMTPEYYANEYRRYQTYVRNYHPDRPIKKICCGANVADYYWTK
                     GVLNTAFDHAEQWHGFMDGLSLHYYVHPEGWEIKGSSTDFDADVWYKTLSKALYMETLI
                     ERHGAIMDEYDPDKKVGMIVDEWGTWYTCEPGTNPGFLYQQNTVRDALVAGITLNIFNK
                     HSDRVKMAALAQMVNVLQSVLLTEGGQMIKTPTYHVMHMYRHHQGADLLESTLTGAGEI
                     GPDEWKVPKITESVSMDKDGVITVTMNNLSVEASEKVEIQLANRGYHVTEAKIVTDSDM
                     HAHNTFEAPDTVTEKDFTAYEETENGVNVTMPANSVIELRLAK"
     CDS             complement(13044..14006)
                     /locus_tag="ctg8_14"
                     /transl_table=11
                     /translation="MSDEKSLKYNEPWILQRADPYVYRHTDGSYYFTASVPAYDGIVLR
                     RAGSLAELSGAEEVMIWKKHESGPMSYHIWAPEIHYLFGKWYIYFAGGEKEDIWKIRPY
                     VLECSGDDPLTDEWVELGKMKRAAEDEFSFEAFSLDATVFENKGEYYYVWAEKVGVGKM
                     ISNLYIAKMESGNQLKTVQVLLTTPDYDWERKGFWVNEGPAVIHHDGKMFLTYSASETG
                     VDYCVGMLSIDEDADILDPRLWKKERYPVLKTCEKLGIYGPGHNSFTMDEDGNDVMVYH
                     ARTEAEINGDPLYNPNRHAMLMKVKWDEAGRPVFSYENK"
     CDS             complement(14191..15576)
                     /locus_tag="ctg8_15"
                     /transl_table=11
                     /translation="MLKAIDDFVWGVPLIVLILAVGIFLTIRLRGLQITKLPLAIKHMV
                     ANEKNGEHGEVSSFGALCTALSATIGTGNIVGVATALVAGGPGALFWMWIAALLGTATK
                     YSECLLAIKYRVVAKDGHIVGGPFYYIENGMGEKWKWLAKIFAFFGVGVGLLGIGTFTQ
                     INGITSAVNNFFDPQNTWTVELFGRTYSWTVVIAGIILTLCVALVIIGGIKRISTVAQV
                     VVPFMALLYVVVVLIILFTHLSAIPGAIVEIVQSAFGLRAAAGGTLGSILIAMQMGIAR
                     GIFSNEAGLGSAPIAAAAAKTNEPVTQGLVSMLGTIIDTVIICTMTGLSIVITRAWDMG
                     LEGVSVTTKAFQIGLPFPEQVASFVLMLCLVFFAFTTILGWNYYSEKCLEYLVGDKKTV
                     LKGYRWLYILAVFIGPFMTVSAVWTIADIFNGLMALPNLVALVALSGVVVAETKKYFEK
                     QKY"
     CDS             complement(15689..17242)
                     /locus_tag="ctg8_16"
                     /transl_table=11
                     /translation="MRKQSKIIFYAGIVLGVAAVLTGVALSGGEKIPKDFTVSYDGIKT
                     ADITAGVSVHDPSVIEADGTYYIFGSHMSGASSEDLRNWTSTGDGYTQSNPIFEDLLGT
                     EHVFDYTGSRDSVIPTDDGTYHVWAPDVVYNRAQDLYYMYFCTSSTWNASNLCYAVSDK
                     PEGPYTWKGALIYSGFTKDTIEATDVLDYVDIDYAKKNYIMAGNKYNYEKYPNAIDPTV
                     FYDADGKMWMVYGSWSGGIFLLEIDEKTGLVIHPKEDEKNGVDPYFGKRLLGGGHKSIE
                     GPYILYDEESGYYYLFVSYGSLTREGGYQMRVFRSKTVDGEYVDMNGAYPGMWDDNAAY
                     GLKLSGNYYLPGLNKAYMATGHNSAFVDEDGKKYIVYHTRFDNGQEYHEPRVHQYFLNQ
                     DGWPCMLPYATDGETIAESGYGISEVAGTYYVIDQGTSISARIAQPVKLVLMENGKVYG
                     ENLEGIWSMEQGTCYMTLTYGEKEYNGVFCQMKDEAGTDVMTFSAVGANESVWGVKYFE
                     "
ORIGIN
        1 catcccgccc ggagggcttt ttaattcata ggacgtaatt tcctatgaat taaaatagaa
       61 tccccggatc accaattccg tgatccgggg attttctttt ttattcattt ataagctgtc
      121 atagcttcgt attttcacta cattttctta ctttgtaagc tgtcctacga cctccgtgaa
      181 tcccataaag tgggatgcct ttaccagaac cgtgtcaccg ctttttacat aaggcagtaa
      241 ttcttccatc agctcatctt ttgttttgaa gtaatgaacc tccgtctcct tactgcattt
      301 tcctactgcc tgtgccagat tctctgataa tgcaccggct gcaaacaaag catcgattcc
      361 ttttccttcg aaatgttctc cgaccatggc atgcagttcc tgctcatttt cgccaagttc
      421 tcccatatct ccaagcactg cgatttttct tccaggtgcc gctgcgagca cgtcgatgga
      481 cgccttcatg gaaacagggt ttgcgttgta acagtcatcg atgatcgtca tcccgccttt
      541 gtggatcaga ttacttcttc ctccgatcgt ttttaccgac tcaatcccgc gtttcatttc
      601 atccacacta agtccaagct ttcctgcaac gcagactgcg gctaaagcat tgtatacatt
      661 atgctctcct gcaatcggga tcgtcactgc aaagctctct gcaccaatat gtatcaccgc
      721 ttttgttcca tctaatccta ccggttccac atctgttgca tatacttcct tttcggcaag
      781 atatttttca ccccgctctg tctttgcagg cttcgcttct tttccgatac cataaaatac
      841 caccggtttt ccgttcacca tctttttctc acagagctta tcatcatctc catttaacac
      901 ggcagttcct tccggtgtca agtgctcaaa actctccgtt tttgccttta aaattccatc
      961 tctggtcagc agattttcca gatggcacaa tccgatattt gtgatcacac agatatccgg
     1021 atatgccatt tcagccagac ggtgcatctc accgaattct gaaattccca tctcaagcac
     1081 tgccacttca tgctgctccc tgatcttaaa aatcgtaagt ggaagaccga tctcgttatt
     1141 gaaattgccc tctgtcttta acacattata cttctgtgaa agaaccgatg cgatcatctc
     1201 ttttgtgctt gtttttccaa cacttccggt aattccgacg accttaatat caagacttct
     1261 gcggtagtat gctgcaagtt ttttcattgc accaagtgtc gattccaccc tgatatatgg
     1321 tcccgccgga tctgacagtt cctgttcgga taatacggca agtgcacctt tttcaaacac
     1381 ctgcggaatg aactgatgac catccacctt ttctcccttt accgcaataa aaagatatcc
     1441 tgactctacc tgtctgctgt cgatcacagc tcctgcaatt tctttctttt tgtcggcctc
     1501 actgccataa tatactccac cgcatacttc cgtaatacgc tccagtgtca tgtttttcat
     1561 gatctacctc atttcccggg attcgttttg cttttacttt tacaaaaata tcttattatt
     1621 tctcatattt atccagggaa atctggatca gtttctcaca cagttcgtta aagttcacac
     1681 caacaacctg tgcctcctgt gggagaaggc ttgtcggagt catgcccggc agtgtattcg
     1741 cctctaaaca gtagatgttt tccttctcat ctaacaggaa atccgtgcgg gagtaagtat
     1801 caagtccaag tacctgtgct acctgctctg catagtgctg cattttctct gtgacagctt
     1861 ctgaaagttc tgccggacag gtctcaacag cactgcctgc tttgtatttg ttcttataat
     1921 cataaaatcc ctgtaccggt gcgatctcga tgatcggaag tgcttttccc tcgatcacgc
     1981 cgacagagaa ctcacgtcct tttacatatt cttccacgat caggttttct tcccagcgga
     2041 acgcctcatc taatgctgct ttatattcct ccgcattgtg tgcgatggaa acaccgatac
     2101 tcgaacctcc gcagcatggt tttaccacac acgggaactg aatgccaagt tttgtgatat
     2161 cgtcgctgcg gtcagccttt ttcatggatg cgccctttgg agccggtatg cctgctgaca
     2221 aaaataattt tttggacatc tccttatcca tggcaagcgc actgcttaaa taaccggttc
     2281 ctgtatagcg gatgccaaac agatcaaatg cggcctgaat cttgccgttt tctccgtttt
     2341 ctccatgcag tgccataaaa acgatatcgg acatctggca taattcgatc acattcggtc
     2401 caaagaaatt gtctgactga tcttttctgg acgcttttac ctttgcaaga tccggtgcag
     2461 tttccggtat tccggatact tttacactga cttcctcact ccggtcaaaa atacctgtca
     2521 gatcttcttt tttatcactg tatcccataa atacatcaag taagattacc tgatgtccat
     2581 tctctctcaa tgcctttgcc accatatctc cggtcttaaa ggaaacatct ctctctgtac
     2641 ttaaaccacc tgctaaaaca acaatcttca tggtatactc tccttactat ctcataaaaa
     2701 catttctgct ttatagtata ccttttttct ttgtgtggca aggaatttgc acattccttt
     2761 gtacttttta tgcctgcatg acatcctttc ttatttattt ttctgcctca cggcaatgcc
     2821 cccggcaggc accatttttt cttttattcc ccgttttccc gtaccggaaa agattcctga
     2881 ctcataaaat tctttgcctg ctgctggcct ctttcacgat aaaacccatt tctacagcat
     2941 tgcgatttct tccatcctca gtgcctgcag cagccacaaa aatatctgtc ttccaatcag
     3001 atcctgtttt ccgatcatac tcccgtaccg gtatatcttt gcaaccacat cctcacagcg
     3061 ttcctcgtcc cccgccagca atatttcaca gagcaatcca taccgctctc tatttaaagt
     3121 gcactgcctg tctatttcat tccatagttc cggatacctt cttgcgagat ccaccagaat
     3181 ctctgccccg ttatacattt cttccgcttt cttctgctct gttatataat tttccacttt
     3241 tacactactg tcatgcaggc attgatacta cacaagtatc ttatgtctgt cgatttttgt
     3301 caactacatt tgatttttat tttgatactt tgataatcaa aatatcttga cattcttttc
     3361 atcatacttt atatttattt ttgtttgata gtcaaactat tttatccgga gggaaaaaaa
     3421 tgagtgtacg aattattgtt gattccgcat ctgatctcac aaaggaacgt gcggatgcat
     3481 taaatcttga ttatatgcct ttaaagacaa tttttggcga aacggaatat ttagacggtg
     3541 ttaccatttc ccataaagaa ttttatgaaa aactgatcga atgcggaaca atcccgacga
     3601 ccagccaggt atctccacat gattttgaag cgaaattcaa agaagtaaaa gaagccggcg
     3661 ataccgccgt tgtgatctgt ctgtcctctc ttttatccgg tacataccag agtgcacaca
     3721 ttgcgcttga tggctatgag gactgtatta cattagttga cagtttaaat gtatgtctgg
     3781 gcgaacagat ccttgtcctt tatgccgtaa agctgcgcga tgaggggctt tctgcgaaag
     3841 aaatcgccga aaaactcgaa gagaaaaaga aagatgtctg tgtcttagcc gtctttgata
     3901 cccttgagta tttaaaacag ggcggacgca tctcaaagac tgccgcctgg gcgggaaata
     3961 ttttatccat caagcctgtc atcgccattg aaaaaggtga ggttgcgatc ttaggaaagg
     4021 ccagaggatc gaaaaacgga aataacatcc tgatccagga agtgaaaaat aaaaacggta
     4081 tcgatttttc catgccgtat atgttaggct acagcgggct cgacgactca ctgctccgga
     4141 agtatattgc ggacagcgca gatctctgga ccggacagac aaaagagctg ccaatcagca
     4201 cgattgggag tacgatcggt acacatgcgg gaccgggagc catctgtgtg tcgtttttcc
     4261 ataaataata atgatgttgg aacaaatatt gatttcaaat ttgtcagtcg ttatgttgtg
     4321 aatcactatt tgccccaaca tcttatcttc gacaaatgct tcacgtcaca caaggaaatc
     4381 tattatgatg tactgcaaaa acccaccctg cggcaaggtg cttgccgcag ggtgggttct
     4441 ttgtattcac agcacaattc tgcaatgatc cattttagta ttccggttcg atcaatccgt
     4501 atgtgttgcc ttttctcttg tatacaacgt tgacatcttc ggtctcagca ttgataaata
     4561 cgaagaagtc atgtcctaat aactccatct gtacacatgc atcttccgga tacatcggct
     4621 tcatatcgaa cttcttagaa cggataatct tgatctcttc atcatcgtct gatgctgcat
     4681 ccaggaaatc ctgtttgaaa acggatgctg cgctctgctg tttcgtaacc agtttcgttc
     4741 tatatttctt taactgacgc tcaataacct cttctaccag atcaattgat acatacatat
     4801 cattgctgac ctgttcagaa cgaatatagt ttcctttcat tggaatcgta acttccactt
     4861 tctggcgttc cttctctacg ctcagtgtta catagacatc tgtgtccgga gtgaagtatt
     4921 tctctaattt gtttaacttg tcctccactg catctttgat accatcggtt aattcaatgt
     4981 ttcttcctgt aatcttgatt ctcatgatgt ccaacccctt tgccgtttat ttgatacaga
     5041 tttatatcat ggttttatta tagcactttc cacaaatatt tcaatacaat atatcatttt
     5101 ttatatattt ttcagaatat ttatattttc ctgtaatatt cttgtaaaaa tgtgcatcat
     5161 tcgctggcac gatcaatatt acacatttaa caagggatgc aatgtcataa tgactcgcca
     5221 ttatgacatt gcatccctta tcatctgttc cgcttttttt gcttcctctt tggtaagctg
     5281 cggtgtatct tttaacacat aatccatgcc aagattatca tacttgacct tgccaagtgc
     5341 atgatatggc agtacttcca atttttccat attggaaagt gtctttagga agtgtccgag
     5401 ttccgtcaat tctgcctcct caaatgtgat gccgggaaca acgacatgac ggatccacac
     5461 cggctttttc ttctgatcta aatatcttgc aaatgccaga atattcttat tggaatgtcc
     5521 ggtcagtttc cggtgatcct cgtcacggat atgcttaatg tcaagcatta caagatctgt
     5581 gacatcaaga agcctgtcta ttttttccag tgtgatatct gatgtggctt ctccatcctc
     5641 cggaaatccc gggaacataa taccagacgt atctaaacag gtatggattc cgtgcgcctt
     5701 tgccttcgca aacagttccg tcagaaaatc gatctgaagc atcggctcgc caccggtggc
     5761 ggtaattcca ccagtccggt aaaacgaggc attgcgcagg aagcggtcga tgatctcgtc
     5821 cgcctccatc tgttttccat cagtcagcac ccatgtatcc gggttgtggc aatactggca
     5881 gcgcatcggg cagccctcga agaatacgac aaaacgcacc cccggaccgt ccacggtacc
     5941 aaatgattcc agagaatgaa tatagcccat tgtgatctcc ttatttttac atcagttcat
     6001 ggaatgttct tgcaattacc tcatcctgct gctctttggt cagtttgatg aagtttactg
     6061 cataacctga tacacggatc gtaagctgcg gatattcttc cggatgcttc tgtgcatcaa
     6121 gcagtgtttc cttatttaat acgtttacat ttaagtggtg accgcctttt tctgcatagc
     6181 cgtcaagcag tgccacaagg tttgtttcag agctttcctc cgtctttcca agtgcatccg
     6241 gcacgatggt aaaggtgttg gaaataccat cctgcgcatc cataaatggc atctttgcaa
     6301 cagaagctaa agaagcaact gcaccatttt tatcacgtcc gtgcattggg tttgcacccg
     6361 gagcaaacgc aacacctttc tttcttccat ctggggttgc tcctgtattc ttaccatagg
     6421 atacattgga tgtaatggta agaatggaag ttgttgcgat accaccgcga taggtgtgat
     6481 ttccttttac atatttgata aaggtatgaa gaacctcttt tgcgatctca tccacacggt
     6541 catcatcatt accatatttc gggaaatctc cctcaatctc aaagtctact gtaataccgt
     6601 tctcatcacg gatcggtttt acttttgcat atttaatggc agaaagggaa tctgctacta
     6661 cggaaaatcc tgcaataccg gttgcaaacc agcgtcttac ctgtttgtca tgtaatgcca
     6721 tctgcattct ctcgtagcag tatttgtcat gcatgtagtg aatgatgttt aatgcattga
     6781 catagacact tgcaagccat ttcatcatgt ctttgtattt atcccatacc tcgtcgtagt
     6841 caagatactc ggaagtgatc ggacgatatt tcggtcctac ctgtttgccg ctgatctcat
     6901 ccacaccacc gttgatcgca tagagtaaac attttgcaag gtttgcacgg gctccgaaga
     6961 actgcatctc ttttccgatt ctcatggaag atacgcagca tgcgataccg tagtcatcgc
     7021 cgtgaaccac acgcatgatg tcatcatttt cgtactggat cgcagaatgt ttgatggaaa
     7081 tctctgcaca gaactttttg aagttctccg gaagttttac agaccataaa acagtcaggt
     7141 ttggctccgg tgctgctccg atgttgttta aagtatttaa gtaacggtaa gacatcttgg
     7201 ttaccatatg tcttccatcc acaccgattc cggcaatcga ctctgttacc caggtaggat
     7261 ctccggcgaa aatactgttg tactccggtg tacgggcaaa ttttacgcag cgcagtttca
     7321 tgatgaactg gtcgatgatc tcctgaatct ctttctccgt gaatgtaccc tcacgaaggt
     7381 cgcgctctgc atagatgtct aagaacgtag aggtacgtcc tagactcatt gccgcaccgt
     7441 tctgctcttt gactgctgca aggtaggcaa aatatacagc ctgtgctgcc tcaagaacat
     7501 ttgttgccgg tttggaaata tcgcatccgt agatctttgc taattctttt aacattttaa
     7561 gggctctgat ctgctccgat aactcctcac gctcacggat aacatcggaa tacatgatgg
     7621 tgcgtgtgga atctaactgc tcctgcttat cttcgatcag acggtctaca ccgtaaagtg
     7681 caggtcttct gtagtcgccg atgatacgtc cgcgcccgta tgcatccgga agtccggtga
     7741 tgatatgtgc ggaacggcag gctctcatct ccggtgtata agcgtcaaac acacccgcat
     7801 tgtgtgtctt tctgtgtgtt gtgaaatatt ctaccacttc cgggtctact ttatacccgt
     7861 tatcttcaca tgccttaatt gccatacgga taccgccata aggctgtaag gaacgtttga
     7921 atggtttatc tgtctggaaa cctacgatct tctccttatc tttgtctaag tacgcaggtc
     7981 catgggaagt gatcgtggaa atgatctttg tatccatatc gagcacgccg ccggcctctc
     8041 tctcctgttt tgaaagctcg agtacatcct gccagagtgc tgtggtgtcc tctgtcggtc
     8101 cctccaagaa agagctgtca ccatcatatg gcttatagtt tctctggatg aagtctctga
     8161 cgtttacttc attctcccat gctccaccat taaaatctct ccattcgttt tgcattattt
     8221 ttcctcctgt ttgctgaaaa ctatggttta cctgtataaa acggatctga tcccccaata
     8281 tttttgtatt gctggaaaat attggtagtt atttctaact tttgttagtt agctctaacg
     8341 cagtgaatat atcatgttcc atcactgctt gtcaatatcc gcttcgtttc cggaactgtt
     8401 ctttttttca tacaaaagga ttcctgtaag aagaatatct ttaagaataa aagaaaccga
     8461 cagtccgggt tatctcgccc agacggtcgg cattgtaaac gttatacttc atgtggttct
     8521 tccacttttt ccgtcagtca tataacaatt agatgttata atttttgatt cattttttca
     8581 ataggtaaaa tgtaccaaaa aaaagcttat atcattgtgt aaattgctat gctgtttttt
     8641 tcttcctttt tgacctgata gagtgctgca tccgctctgt gatacagttc acggaagctt
     8701 gtgccatcct cagggccgaa tgcgatgcca atacttgctg tcggctcctc cgccattccg
     8761 atcatttctt tttgtctgcg cagccggtac agcacttcat ctgcctgccc ctgtatccac
     8821 atacggtctt ttacatccgg aagaaatact gcgaattcat ccccgcccat acgtccaatg
     8881 ctgacctgat taccgtagac ttcccttaaa atattagaca cactcataat gacgcggtcg
     8941 ccaacccagt ggccatacac atcattgacc tgcttaaaat tatccagatc aatagcaatg
     9001 tatgcataat tttgtccttc tgccactgac tccagttctt ctttgatacg atcttccatc
     9061 gtaccacggt ttaacagtct cgtcatggaa tctctggctg cacaatcccg taaatattct
     9121 ctttctctcg cgtaacgtct gtttttttcc actttctccg ttacatccgt gatcgtaata
     9181 taactgaccg gttttaactg cgaggatata acatccatgg ataccatcac acgaaaagac
     9241 agccactttt tatttccgtc tttcgtctct gtctgagcag tcagttcaaa tgactcccct
     9301 gtcagaatct cttcatgatg ctccctcatg accattctta agtcaatatc cacaaaccgg
     9361 ctccagccgt cctgtacttt ttcaataaat tcctccctcg tgtaaccgag catatggtac
     9421 gccatcgtat tcacataata caccttgcgt tttctgccct cactgctcac aacaagacca
     9481 aacggtacgt ttttcataac tttatgaaaa accttttcct ccaataccga gctttccatt
     9541 ctccctctcc cgttaaaaaa ttaactaatt gatcccccga acattatact acattacttt
     9601 aaaataaaaa agtattttta tgaatatttt tctttcttct agacttccat acttttttcc
     9661 tatataattt atctaattat ttttttactt aatggagaaa attagtatga aaataacatt
     9721 tttcacgcaa gaatggagaa ttttatgaaa attggcatta tttctgatac acacggtatt
     9781 ttccgtgaag agtggcaccg tcatttagac ggctgcgatt atctgatcca tgcaggcgat
     9841 ttctgtacgc agaaaaatta tgactgtttc cggaactttg gcattccgct ttatatggtc
     9901 cgaggcaaca atgaccgcgg tgactgggcc aaaaatcttc ctgaattttt acagttccgc
     9961 attggcggca agactttttt tctggttcat aatcagtttg atcttccatt tgacctgaca
    10021 gatgctgatt ttcttatctt tggtcatact catcactata cattttataa acgtttcaat
    10081 aaagtttata ttaatccggg cagtgccagt gacggacgtg gagattcgaa aagtcttgca
    10141 atcctgacac tttcaggcaa tgattacagt ttagaacgtg tcattctgtg atttttacag
    10201 attttgaaag gagaggattt ccttgttaca catcacttcg ttgaatgaag ggttagaact
    10261 ttttaaggca ctcggttctg atgtgagaat tgaaatttta aatattttgc tggaaaacga
    10321 caatatgagc atgaatgaac ttgcctcccg tttaaatatt acaaacggtg ccttaaccag
    10381 ccatatcaaa aaacttgaga actgcggact gatcacaaca tccagtgaat ctgctgttca
    10441 cggcaatcag aagatctgtt cgatccattt agataaaatc ctgatcgatt tagaaaagcc
    10501 tgccgaaatt gagaatgttt atcatacgga attaaaagtc ggccattata caaattatca
    10561 gatctgcccg acctgcgggc tcgcctccgc agatgccctg atcggcgagg tggacgatcc
    10621 gcggtatttt gaacatccgg accgctataa cgctgatatt ctatggttta cacgcggtta
    10681 tgttgaatat gccattccaa attttatccc ggcttccaaa aaaatcacac agatcacaat
    10741 ttccgcagaa cttagttccg aagcaccagg caccaacaat gactggcctt ccgatatcag
    10801 tttttactta aatgatattc atattggtga ctggacctcc cccggcgatt ttggcgatgt
    10861 gaagggtctg ttgacaccgg actggtggta tgcaaactgg aaccagtacg gattgctaaa
    10921 acaacttgtc atcaatcaaa aaggtaccta tatcgacggt ctcaaaatat ccgacgttaa
    10981 aatcgatgat ttccatctca actgccacag cagcatccgc ttccgcctgg ctgtggagga
    11041 cgatgccagg cacgtcggcg gacttacgat ctttggaaaa tcttttggca attacagcca
    11101 ggatatcaaa gtgagtctcg ggtacgcccc ggtggaggaa atgaagtaat attaccgcaa
    11161 taaaaaatgg taacagtccg tctgaactgt caccattttt tatatgggca ttttgatacg
    11221 gctgccgcgg cgcgcagctc tacatagcag ccgcacgcac cgcaggttcc cgcgtttaaa
    11281 agttcacagg ttttgcagac agtaagccgt ctctcatact cgctctctga tacctgatct
    11341 tcttttttga tcgcctcttt atatttctca atcatttttg catccgcttc cgccatttcg
    11401 cgcagcagac actttttaca gatctgtgcc atatgtcatc tccgcctgta attttcgtta
    11461 ctgttcatat ttccagtatg accagcagct aattttcccg ccattgctga cagttttttt
    11521 cttattttgc aagacgcagc tcgatcacac tgtttgccgg cattgtgaca ttcacgccgt
    11581 tttccgtctc ctcataggca gtaaaatctt tttctgtcac ggtatccggt gcctcaaatg
    11641 tgttatgtgc atgcatatcg gaatcggtta cgatctttgc ctcagtcaca tgatagccac
    11701 ggtttgcaag ctggatctcc accttttccg atgcctccac agagaggttg ttcatggtga
    11761 cggtgatcac accgtcttta tccatggata cggactctgt gatcttcggt actttccact
    11821 catccggtcc gatctcacct gccccggtca aagtgctctc taacaggtct gcgccctgat
    11881 ggtggcggta catatgcatg acatggtagg tcggtgtctt tatcatctgg ccgccctctg
    11941 tcagaagtac agactgtaaa acatttacca tctgtgctaa cgcagccatt ttgacacggt
    12001 cactgtgctt gttaaaaata tttaaggtga tacctgcaac aagtgcatca cgcaccgtat
    12061 tctgctgata caaaaatccc ggattggtgc ccggctcgca ggtataccag gtgccccact
    12121 cgtccacgat cataccgact tttttatccg gatcgtactc atccataatc gcaccgtggc
    12181 gttcgatcaa tgtctccata taaagcgcct tcgataatgt cttataccag acatccgcat
    12241 caaagtccgt agaacttcct ttgatctccc agccctccgg atgtacatag taatgaagtg
    12301 atagaccatc cataaatccg tgccactgct cagcatggtc aaatgccgta tttaacactc
    12361 cttttgtcca gtaatagtct gcaacatttg caccacagca gatctttttg atcggacggt
    12421 ccgggtgata attgcgcaca taggtctggt atctgcggta ctcatttgca taatattccg
    12481 gcgtcatatt tccgccgcat ccccagtttt cattgccgac accaaaatag tccactttcc
    12541 atggcgcctc atgtccgttt tcttttctca aatctgccat cggggagacg ccctcaaagg
    12601 tcatgtactc cacccactct gacatctcac ggacagttcc gcttccaaga ttgccgttaa
    12661 cgtaagtctt acagccgatc tgacggcaca gttccatata ttcatgtgtt ccgaaactgt
    12721 tatcttccac aacaccaccc cagtgtgtgt tgatcatttt tttacgcttt tccttcggtc
    12781 cgattccgtc catccagtga tattcgtccg caaagcagcc acccggccag cgcagtaccg
    12841 gaacttttaa ttcctttaat gcgtccacaa catcagtgcg catgccgttt acattcggaa
    12901 tctccgattt ttcgccgacg taaattccct cataaataca tctccccaga tgctccgaaa
    12961 aatgtccata gatttccggc tcaatacgac tctttttgtt ttcctcattg atgatcagtt
    13021 ttgccattgt tttctctcct tttttattta ttttcatagg aaaataccgg tcttccggct
    13081 tcatcccatt ttaccttcat aagcatcgca tgacgattcg gattgtacaa cggatctccg
    13141 ttaatttctg cctccgtccg cgcgtggtag accatgacgt catttccatc ttcatccatg
    13201 gtaaacgagt tgtgtcccgg cccgtaaatg cccagttttt cacaggtttt taataccggg
    13261 taacgctctt ttttccacaa acgcggatct aaaatgtccg catcctcatc gatggataac
    13321 attcccacac agtaatccac acccgtctcg ctcgccgagt atgttaagaa catttttccg
    13381 tcatgatgga tcacggcagg tccctcgttg acccagaacc ctttccgctc ccagtcgtaa
    13441 tccggcgtgg tcaaaagtac ctgcaccgtt tttaactgat tgccggattc catctttgca
    13501 atgtagagat ttgaaatcat tttgccgact ccgacctttt ctgcccagac ataataatat
    13561 tcacctttat tttcaaagac ggtcgcatcc agcgaaaatg cctcaaaaga aaactcatcc
    13621 tccgctgcgc gtttcatctt tccaagttcc acccactcat ccgtcagcgg atcgtccccg
    13681 ctgcactcta acacatatgg acggatcttc cagatatctt ccttctcgcc tcccgcaaaa
    13741 taaatatacc actttccaaa cagatagtgg atctccggtg cccagatatg ataactcatc
    13801 ggaccggact catgtttctt ccagatcatg acctcctctg ccccggaaag ttccgccagt
    13861 gatccggcac gtctcaatac gatcccgtca tacgccggaa ccgacgccgt aaaataatac
    13921 gagccgtccg tatgacggta aacatatgga tccgcacgct gtaaaatcca cggttcattg
    13981 tactttaaag atttttcatc tgacatgcag tatcctcccc tctgatgaca ttcgcactgt
    14041 ttctttctta tgacagtata ctccttattt tttgttttgt atagattatt ctaaaatatt
    14101 atatactttt ctaaaatcaa aaaacgcaga ctacatcacc aggcaaaaaa acagcggaag
    14161 cactctgcct ccgccatttt ttatttctca ctaatatttc tgtttttcaa agtatttctt
    14221 cgtctctgca actaccaccc cactcaaagc aacgagtgca acaaggttcg gcaatgccat
    14281 cagcccgtta aagatatctg cgatcgtcca tacagcagat accgtcataa atggtcctat
    14341 aaacactgca aggatataca gccagcgata tccctttaaa acagtctttt tgtccccaac
    14401 cagatattcc agacattttt cactgtaata attccatcca aggatcgtcg taaatgcgaa
    14461 gaatacaaga cataacatta acacaaaaga tgccacctgc tccgggaatg gcagtcctat
    14521 ctgaaatgct ttcgtggtta cagagacacc ttctaatccc atatcccagg ctcgtgtgat
    14581 cacgatggaa agtccggtca tcgtacagat gatcaccgtg tcaatgatcg ttcccagcat
    14641 ggatacaagt ccctgtgtca ccggctcatt tgtctttgcc gctgccgctg cgatcggcgc
    14701 actgccaagt cctgcctcat tcgaaaagat tccgcgggca attcccatct gcatggcgat
    14761 caggatcgat ccaagggttc cgcctgcagc cgcacgaagt ccaaatgcac tctgcacgat
    14821 ctctacgatt gctcccggaa ttgcgctaag atgcgtaaat agtatgatca gtaccacaac
    14881 gacataaagc agtgccataa aaggtaccac aacctgtgct actgtggaaa tacgcttaat
    14941 accgccaatg ataaccagtg ccacacacag tgtcagaata atacctgcga tcacaaccgt
    15001 ccaggaatag gttctgccaa acagttccac cgtccatgta ttctgcggat caaagaaatt
    15061 gttcacggca cttgtgatcc cgttgatctg cgtaaaagtt ccgattccaa gtaaacctac
    15121 tccgacaccg aaaaatgcaa aaatttttgc gagccatttc catttttcac ccattccgtt
    15181 ttcgatgtaa taaaacggtc ctccgacgat atgaccgtcc tttgccacaa cacggtattt
    15241 aattgcaagc agacactcgg aatatttcgt cgccgttcca agcagtgctg cgatccacat
    15301 ccagaacagt gcacccggtc ctccggcgac aagcgcggtt gccacgccga caatgttacc
    15361 tgttccgatc gttgcagaca atgctgtgca gagtgcgccg aaacttgaaa cttccccgtg
    15421 ttctccgttt ttttcatttg ccaccatatg ttttatggca agcggcagtt tcgtgatctg
    15481 aagtccacgc agccggatcg taagaaagat accaaccgct aagatcaaca cgatcagtgg
    15541 aactccccag acgaaatcat caatcgcttt taacatttgt acccgttcct ttcccaaaac
    15601 tttagatacg taccacatta ccatgggaaa gagttctttg caagtatttt atgctccgtc
    15661 tgccgtttct cacgtctttg ctttcatttt actcaaaata tttaacgccc cagacactct
    15721 catttgctcc aacagcagaa aatgtcatga catccgtgcc tgcttcatct ttcatctgac
    15781 aaaatacacc gttatattct ttttccccgt atgtgagcgt catataacag gtgccctgct
    15841 ccatactcca gatgccttct aagttttcgc cgtacacttt tccattctcc atcagtacca
    15901 gttttaccgg ctgtgcaatc ctggcactaa ttgaggttcc ctgatcaatc acatagtaag
    15961 ttcctgccac ttccgaaatg ccataaccgc tctctgcgat cgtctcaccg tccgtcgcat
    16021 acggaagcat acacggccat ccatcctgat tcagaaaata ctggtgtaca cgcggctcgt
    16081 gatattcctg tccgttgtca aagcgcgtgt ggtatacaat atatttcttt ccatcttcat
    16141 ccacaaaagc tgaattgtgc ccggtcgcca tatatgcctt attaagaccc ggcagataat
    16201 aattgccgga aagttttaag ccataagctg cattgtcatc ccacatcccc ggatatgccc
    16261 cattcatatc gacatactct ccatccaccg tttttgagcg gaacacacgc atctgatagc
    16321 cgccctctct cgtcagggaa ccataggaaa caaacagata ataatatccg ctttcctcat
    16381 catagagaat gtaaggtccc tcgatcgatt tgtgtccgcc gccaagcaga cgtttgccaa
    16441 aatacggatc cacaccgttt ttttcatctt ctttggggtg gatgaccagg cctgttttct
    16501 catcgatctc taacagaaaa atcccacccg accatgaacc gtagaccatc cacatttttc
    16561 cgtccgcatc ataaaaaacg gtcggatcga tcgcatttgg atatttctca tagttatatt
    16621 tatttcccgc catgatgtag ttcttttttg catagtcgat gtccacataa tcgagcacat
    16681 cggtcgcctc gatcgtatct tttgtaaatc cggaatagat gagcgctccc ttccatgtat
    16741 acggtccttc cggtttatct gaaaccgcat aacacagatt cgatgcattc caggtcgaag
    16801 acgtgcaaaa atacatgtaa tataagtcct gtgccctgtt atagaccacg tccggtgccc
    16861 agacatgata agtcccatcg tcagtcggta tcacagagtc tctgcttccc gtataatcaa
    16921 atacatgctc tgttccaagc agatcctcaa agatcggatt cgactgcgta tatccgtcac
    16981 cggtcgatgt ccagttccgc agatcctcag atgatgcccc tgacatatgc gatccgaaaa
    17041 tgtaataggt accgtccgcc tctatcacgg atggatcatg tacactgacg cccgccgtaa
    17101 tatccgccgt tttgattcca tcataactca ctgtaaaatc cttcgggatc ttctctcccc
    17161 ccgacagtgc cacccccgta agcactgcag caacccccaa tacaattcct gcataaaaaa
    17221 tgattttgct ttgttttctc atacggctcc tccatttctg tatgatatct aactctacaa
    17281 tag
//
