LOCUS       c00049_gnlPro..        15253 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FIAIMDAH_49.
ACCESSION   c00049_gnlPro..
VERSION     c00049_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:03:00
            Original ID  :: gnl|Prokka|FIAIMDAH_49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15253
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15253
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[18:5253]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      19..5253
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15253
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15253
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             19..921
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_1"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-12, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.9e-09, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1e-08, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.1e-08, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.3e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-05, bitscore: 16.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDTA
                     PQVKVAVPKAEVETPKAEV"
     CDS             982..2319
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_2"
                     /sec_met_domain="Fer4_10 (E-value: 4e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 8.1e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.3e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 9.6e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.5e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             2326..3318
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.3e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             3336..3980
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_4"
                     /sec_met_domain="FMN_bind (E-value: 4.7e-24, bitscore:
                     75.6, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKNMLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAV
                     VPGFDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEG
                     KIIDYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTI
                     TSRAFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             3922..4581
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_5"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.9e-71, bitscore:
                     229.4, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNNLLIPQLPKLWIHSALNKKGVEDMNNFKVMMNGIIKENPTFVL
                     LLGMCPTLGTTSSAINGMGMGLATMFVLICSNVVISAIKNLIPDMVRIPSFIVVIASFV
                     TLLQMIMQAYVPALYATLGLFIPLIVVNCIVLGRAEAFAAKNNPVASLFDGLGMGLGFT
                     IALTLLGAVREFLGTGKIFNLSILPEEYGMLVFVLAPGAFIALGYLIALINSMKKN"
     CDS             4669..5253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.3e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             5385..6419
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.1e-53, bitscore:
                     173.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKILVTGGTGYIGSHTVVELQNAGYEVVIIDNLSNSSADVVDN
                     IEKVSGIRPAFEELDCLDYAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVVAIRRILENKQKEKVEVFNIGTGRGLSVLELINA
                     FEKATGVKLNYQIVGRRAGDIEKVWANPELANNELGWKAETSIEDTLLSAWKWQLKLRE
                     RGIQ"
     CDS             complement(7054..7692)
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MAFLHTFLEFFSVTDNAGFYHFSQQVVAFTCTFSYTGKHREAVLL
                     LRNIINELLDKHRLAYTGATKQTDFTALAIWFQQVDNLDACIKHLLYGSQIFKLRGVAM
                     DGISTCTVQLLHAVDRVAHYVHQAAFDLCTYRHGDGASQRMHCHSSLQAVRTVHSNSTH
                     RVFTNVLLYLYNQSFAVRPFYFQCVVNTRQHHFCLRSFEIDVYYRPDYL"
     CDS             7699..8565
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="LSKVDYDEVAKSQVSLIFGQMNEPPGARQSVALSGLTVAESFRDM
                     GAETDGPRDILFFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTR
                     NGSITSVQAVYVPADDLTDPAPATTFTHLDATTVLSRKITELGIYPAVDPLESTSRILD
                     PHIVGVEHYEVAQRVKQILQRNKELQDIISILGMEELSDADRTLVNRARRVQRFLSQPF
                     AVAEQFTGVPGTMVSIEDTIKGFKMILDGEVDYLPEPAFLNVGTIEEAIEKGKKLLEQA
                     GGKTIKN"
     CDS             8582..8833
                     /locus_tag="ctg49_10"
                     /transl_table=11
                     /translation="MMKKLHLNIVSPEKELFNGEVESVTLPGTMGSFSILPQHAPIVSS
                     LGTGKLIYATDGEEHELDIQSGFVEMSNGRVAVCIEQQ"
     CDS             8875..9294
                     /locus_tag="ctg49_11"
                     /transl_table=11
                     /translation="VTITKRNYLLHTALLTVLIGIVGGWAYFSINPHHYFGGYPLIPLF
                     FFVFGVFMINMTESCRHRMPGRMLQIYLLMRVMRMLVSMIVMLFYCVAVREEARAFLLT
                     FIANYLIYLIYDSWFFFTFEANRKLKKKSNNEKIA"
     CDS             9287..10348
                     /locus_tag="ctg49_12"
                     /transl_table=11
                     /translation="LRNILTVILLALGMLLPATVRAENTVDVKEIVFGHIGDSYEWHIT
                     TWGETHVTIPLPVIVHSSTTGWHAFLSSRLEENGGSYEGFSIAPAGSKYEGKLVEYDAT
                     GNEIRPLDISITKVTLALLINSALLLLIILSVAHWYRKHPQGSAAPGGFIGFMEMFIMM
                     VNDDIIKSCVGPKYRKFAPYLLTAFFFIFINNIMGLIPFFPGGANVTGNIAITMVLAIC
                     TFLAVNIFGTKTYWKDIFWPDVPWWLKVPVPMMPFIEFFGIFTKPFALMIRLFANMLAG
                     HMAMLVLTCLIFISASMGPALNGTLTVASVLFNIFMNALELLVAFIQAYVFTMLSAVFI
                     GLAQEEHKEKAVK"
     CDS             10405..10662
                     /locus_tag="ctg49_13"
                     /transl_table=11
                     /translation="MLLSVLLQAAAAGVGVSKLGAAIGAGLAVIGAGVGIGKIGGSAME
                     AIARQPEASGDIRMNMIIAAALIEGVALLAVVVCLLVFFL"
     CDS             10764..11264
                     /locus_tag="ctg49_14"
                     /transl_table=11
                     /translation="LLLPDSGLLFWMLLSFGVVFVVLAKYGFPVITKMVEGRKTYIDQS
                     LEVAREANAQLSKLKEESEALIAAANKEQGRILREAMHERDKIIVEARKQAEAAAQKEL
                     DEVKKQIQQEKEEAIRDIRRQVAVLSVDIAEKIIRKNLDEKHEQMEMIDRMLDEVLAAS
                     KNN"
     CDS             11276..11836
                     /locus_tag="ctg49_15"
                     /transl_table=11
                     /translation="MDIGIVSMRYAKALMEYAKSMGAEDTLYKEFCMLDRSFRKHPDLR
                     MALENPILTIREKLTLICTAAVGDAPAGREFARFMTLVLKNRRENFLQYICLSFLDLYR
                     KDKHIGVGKLITAVPVSQEVRERIHDSASSLLHASMELQTEVDPSIEGGFIFDINDFRL
                     DASIATQLKKVKQQFIDKNRRIV"
     CDS             11967..13553
                     /locus_tag="ctg49_16"
                     /transl_table=11
                     /translation="MLSENIKVSEVSDILRKQLEGIDTRVQLDEIGTVLQVSDGVARIY
                     GLRNAEANELLEFDNGIKAIVMNLEEDNVGAVLLGPTDKIKEGFIVKRTKRIASIMVGE
                     GMLGRVIDPLGAPLDGKGLIGGELYEMPLERKAPGVIFRQPVNQPLQTGLKAVDAMIPI
                     GRGQRELIIGDRQTGKTAIAIDTIINQRANFDAGDPVYCIYVAIGQKGSTVASIVNTLH
                     QYGAMDYTIVVAATAGDPAALQYYAPFAGAAIGEYFRDTGRHALVVYDDLSKQAVAYRE
                     VSLILRRPSGREAYPGDIFYLHSRLLERAAKIISQEEVAREMNDLPDSLKGKVKGGGSL
                     TALPIIETQAGDVSAYIPTNVISITDGQIFLDTNLFNQGNRPAIDVGISVSRVGGNAQV
                     KAMKKVAGTLKIDQAQYRELEAFTKFSGDMDPVTALTIDKGQKNTRLLVQPQYSPMPVE
                     KQIAILYCGTHGLLRNVPLDKVSEFERNFLESLEMNYRMEVLDVLKTGAINDDVCKKIE
                     ETAEAVARQFM"
     CDS             13675..14565
                     /locus_tag="ctg49_17"
                     /transl_table=11
                     /translation="MSSLKEVKNRISSVKSTRQITSAMKMVASAKLHKAQGRIENMLPY
                     QRKLNEILTNFLRTDASFESPYTEKRPVTRVAVVAFSSNSSLCGAFNSNVAKMLERALE
                     DYQSLGKENILIYPVGRKMEEAVKKMGYVPQGSYQVMADKPSYVEAYELAEKLMHEFVE
                     KQIDHVELIYHHFKSMGSQVLLRENYLPIDLTQVAQEAAEDVPEDARSFNNDYIVEPSV
                     GELIAELLPKVLSQKIFTVLLDSNTSEHAARMLAMQTATDNANELIQDLTKQYNKSRQQ
                     AITNELLDIIGGSLK"
ORIGIN
        1 ttaataaaca actaatttat gaatgtaatt ctgattgcag tgatttcatt gggagttata
       61 gcgctggtat cggccgctat tctttacgtg gcttccaaga aattcgccgt gtatgaagat
      121 ccgcggattg cccaggtagc agaggtgctt ccccaggcaa attgcggtgg atgtggttac
      181 cccggttgta gcggatttgc agatgcttgc gtaaaggcag gttcgctgga tggtaaactt
      241 tgtccggtgg gtggacagcc cgtcatgaca aagattgccg agattctggg cttggatgcc
      301 gctgctgccg aacctatggt tgcggtggtg agatgtaatg gaacttgtgc caaccgtcct
      361 cgtgtgaacc aatacgatgg cgccaagagt tgtgccattg cggcttctct ctatggtggt
      421 gaaacgggtt gtagttatgg ctgtctggga tgcggcgact gtgtggctgc ctgccagttc
      481 gatgctatcc acatgaatcc ggagaccgga cttcccgaag tggatgagga aaagtgtacg
      541 gcttgtggag cttgtgccaa ggcttgtccg aaatctatta ttgaaatccg tcctcaaggc
      601 aagaaatcac gtcgtattta cgtacagtgt gtaaacaagg acaagggggc cgtagcacgc
      661 aaggcttgta ccgtggcatg tatcggttgc ggcaagtgtg tgaaggtttg tccgttcgag
      721 gctatcacgc tggaaaacaa tctggcttac attgacccca ataagtgtaa atcctgtcgc
      781 aagtgcgagg aagcttgtcc gcaaaacaca atcattgccc tcaacttccc gccgcgcaaa
      841 ccgaaggctg acgatacagc tccccaagta aaggttgcag ttcctaaagc tgaggttgag
      901 actcctaaag cagaggttta gacttcccaa gttgaggtat gaattaataa agtaaataaa
      961 cgactaaaaa tacagaattg tatgttgaag acattttcaa ttggtggagt ccatccacac
     1021 gaaaataaac tttcagcaca tcagcctatc atcaaggcag agattccggc caaggccgct
     1081 atcttgctgg gacagcacat cggtgctcct gccaagccta tcgttgccaa aggtgatgtt
     1141 gtgaaagtgg gtacaaagat tgccgagccc ggcggttttg tatcagcagc cattcattcg
     1201 tctgtcagcg ggaaagtcgc taagattgac acgattgtcg atgccagcgg ttacgccaag
     1261 cctgctatat tcattgacgt agaaggggat gaatgggaag aatccattga ccgttccgaa
     1321 acgttggtga aggaatgcag tctgacctcc gaggaaatcg tgaagaaaat cgctgatgcc
     1381 ggtatcgtag gtctgggcgg tgcatgcttc cctacgcagg tcaagttgtg tcctcctcct
     1441 gcattcaagg cagagtgtgt catcatcaac gccgtagagt gcgaaccgta tctgactgcc
     1501 gaccatcagc tgatgctgga acatgcggaa gaaattatgg taggtgtatc cattctgatg
     1561 aaggcggtaa aggtgaacaa ggcattcatc ggcattgaga acaataagcc cgatgccatc
     1621 cagctgatga cgaaggttgc ttccagctat gcaggtatcg aggtggtacc cttgaaggta
     1681 caatatccgc agggtggtga aaagcagttg attgatgctg tcatcagtcg ccaggttgca
     1741 gccggtgcgt tgcctatctc cacgggagct gtggtgcaga atgtgggtac cgcatttgcc
     1801 gtttaccagg ccgtacagaa gaacaaacct ctgtttgagc gtgtcattac cgtgaccggt
     1861 aagtcgttgg caaagccgtc caatttcctg gcacgtatcg gtacgccgat gaagcagctg
     1921 attgaagctt gcggcggttt gcccgaagat acgggtaaga ttatcggcgg tggcccgatg
     1981 atgggtaaag ctctggtaaa tacggatgta ccgacagcca aaggaagctc cggtattctg
     2041 attatgaacg agaaggaagc caagcgcggc gaagtacagc cttgtatccg ttgtgccaag
     2101 tgcgtgggag cctgcccgat ggggttggag ccgtatctgc tggctaccgt ttcggcccac
     2161 ggagattttg aaagagtaga gaaagaagac attatgtcgt gtatagaatg cggttcatgc
     2221 cagttcactt gtccttccaa ccgtccgatg ctggattata tccgcttggg taagggtaag
     2281 gtaggagcga tgatccgtgc acgtcaagct aaaaaataac gaagtatgaa taaattaatc
     2341 gtatcccttt cgccccacgt tcacggcggt gacagcgtga agaagaatat gtacggtgtg
     2401 cttatcgcat tgattccggc attcctcgtt tcgctttact ttttcggact gggtgcgctg
     2461 attgttacgg caacttccgt agcagcctgc ttgttctttg aatgggccat cggcaaattc
     2521 ctcatgaaaa aagagaccac aaccatcacc gacggctctg ccatcattac cggtgtgttg
     2581 ctggccttta acctgccttc caacctgccc atctggatta tcatccttgg tgccttgttt
     2641 gccatcgggg taggcaagat gtccttcgga ggtttgggtt gcaatccctt taaccctgca
     2701 ctggcaggac gtgtattcct gttgctttca ttccccgtgc agatgacgac atggccggct
     2761 gtaggccagt tgacagccta tacggatgcc acgacggctg ctacgccgct ggctattatg
     2821 aaaggtgtca tcaatggtgc tccgggcatg tccctgagcg accttccggg agctttcgac
     2881 cttctgatag gtaataatgg aggatgtctc ggtgaggtga gtgctttggc gctgctgctt
     2941 ggtttgttct acatgttgtg gaagaaaatc atcacctggc acattccggt atctattctg
     3001 gtgacggtat tcgtgttctc cggtatcatg tatctggtca atccggaact ttatgtatcc
     3061 ccggtcgtac agttgttgtc cggtggtctg atgctgggtg ctgtctttat ggctacggac
     3121 tacgtgactt ctccgatgag ccacaaaggt atgctgattt atggtgtttg catcggccta
     3181 ctgactgtca tcatccgtct gttcggtgca tatccggagg gtatgtcgtt tgccattctg
     3241 attatgaatg cgttcactcc gctcatcaac acctatgtta aacctaaacg ctttggggag
     3301 gtagcgaaga agaaatgaaa aagttagaat catccttgaa gaatatgttg ctggtactta
     3361 cgggcgttac cgcaatctcc gtagcgttgc tggcttatgt aaacgaattg acgaaggagc
     3421 ccattgcgca ggccaatgca aagaccttga gcgatgccgt aagtgcggtg gttccgggct
     3481 tcgacaatga ccccattgcc gagaagaaga tgcaggaagt aaacggagta cagtattctg
     3541 tatatcctgc caccaaaggt ggagaatata tcggagctgc tgtggaagct gttgccatgg
     3601 gttttggcgg tgagctgaaa gtgttggtcg gtttcgatgc tgaaggcaaa atcatcgact
     3661 actccttgtt gtcgcatgtg gaaactccgg ggttgggttc caaggctgcc gactggttca
     3721 agaaaggcaa taaaggtgac atcaccggca tgaatccggg tgaagctgca ttgacagtga
     3781 gcaaggacgg tggtaaagta gatgccatta cagcgtctac catcacctca cgtgcttttt
     3841 tgaatgcagt gaatgcggct tatgctgcct atgccggtca ggaaactgcc gacggcacta
     3901 ccggcgctac tcaaaagaat gttgaacaac ctgctgattc cgcagctccc gaagctgtgg
     3961 atacactcag cgctaaataa gaaaggagta gaagatatga ataattttaa agttatgatg
     4021 aacgggatta tcaaagagaa tcctacgttt gtactcctgc tgggtatgtg tcctacactg
     4081 ggtaccactt cctctgccat taacggtatg ggtatgggac tggctacaat gttcgtgctg
     4141 atatgttcca atgtggtgat ttctgccatc aagaatctga ttcccgatat ggtgcgtatc
     4201 ccttcattca ttgtagtcat agcatcattt gtgacactgt tgcagatgat aatgcaagct
     4261 tacgttcctg cattgtacgc cacactgggc ctgttcattc cgctgattgt tgtaaactgt
     4321 atcgtattgg gacgtgccga ggcatttgct gccaaaaaca atccggtggc ttccttgttc
     4381 gacggtctgg gcatgggctt gggctttacc attgcactga cattactggg tgccgtgcgt
     4441 gagttcctgg gaaccggcaa gatattcaac ttgagtatcc ttcccgaaga atacggcatg
     4501 ttggtatttg tccttgctcc gggtgcattc attgcattgg gctatctcat tgctttaatc
     4561 aacagtatga agaagaatta ataatgaaaa attaaaaatg aaaaaattga gaacgtatcg
     4621 gcggtaagct gccgggcttt taatttttag tttttaattc ttaatttaat gattatggaa
     4681 tatatattga tatttatctc ggcaatcttt gtaaacaaca tcgtattgtc gcaattcttg
     4741 ggaatttgcc cgttcttggg agtttccaag aaagtggaga ctgcattggg catgtcggca
     4801 gcggtggcat tcgtgctcac catcgccact atcgtgacat tccttattca gaagtatgtg
     4861 ctcgacgctt ttgatttggg ctatttgcag actattacct ttatcctggt gattgccgca
     4921 ttggtgcaga tggtagagat tatcctgaag aaagtttctc cttctctgta tcaggccttg
     4981 ggcgtgttcc tgccgttgat tactaccaac tgctgtattc tcggtgtggc tatccttgtt
     5041 atccaaaaag attatgattt gctgacggga gtggtttatg cattctccac ggcacttggt
     5101 ttcggcttgg cactgacact gtttgcaggc ctgcgcgagc aaatgagcct ggttagtgta
     5161 ccgaaaggta tgcagggtac tccgatagct ttgattactg ccggactgct ggcaatggca
     5221 ttcatgggct tttcgggggt tgtgaagatt taaagaagaa aaaacggaaa taaagtggaa
     5281 gggggataaa ctaaaattta tccccctttt tctgttttta ttaatttatt tccttacatt
     5341 tgtggcgtat tgataaccta aaagctaaat tatctatatt taatatgaaa gggaaaatct
     5401 tagttacggg tggaaccggt tatattggtt ctcacacggt ggtggaactt caaaacgcag
     5461 gttatgaagt tgttattatt gataatttgt caaactccag cgcagatgtt gtagataaca
     5521 tagagaaggt atcgggcatc cgccctgcat tcgaggaatt ggattgcttg gattatgccg
     5581 gtcttgacgc tgtgtttacc aaatataaag gcattaaagc catcattcac tttgcggcca
     5641 gcaaggctgt gggtgaatct gtccagaaac cgttgcttta ctatcgtaat aacctggttt
     5701 cactgataaa cctgctggaa ttgatgccga agcatggagt ggaaggtatc gtattctctt
     5761 cttcctgcac agtttacggc cagccggacg aacttccggt aacggaaaag gcacctatta
     5821 agaaagctga gtctccgtat ggaaacacga agcaaatcaa tgaagagatt gtacgtgata
     5881 cggttgcttc cggtgctccg ataaacgcca tcttgttgcg ttacttcaac ccgataggtg
     5941 cacaccccac agcattgctg ggagagttgc ctaacggtgt accgcagaac ttgattcctt
     6001 atcttaccca gaccgctatc ggcatccgtg agaaactgag cgtgtttggt gacgattatg
     6061 atactcccga cggttcttgt atccgcgact tcatcaatgt agtcgatttg gccaaagcac
     6121 acgtagtggc tatccgccgt atcttggaga acaagcagaa ggaaaaagtg gaagtattca
     6181 atatcggtac aggtcgtgga ctttccgtat tggaactgat taatgctttc gaaaaggcta
     6241 ccggtgtaaa actgaactat cagatagtag gtcggcgtgc cggtgatatt gagaaggtat
     6301 gggcaaaccc ggaattggca aacaatgaac tgggttggaa ggcagaaaca agtattgaag
     6361 atactttact ttctgcatgg aaatggcagt tgaagcttcg tgaaagaggt attcaatgac
     6421 aaactttgaa tttgtgtttt ttaacaaata ggcaataaac aaatgcctcc ccgcatttgt
     6481 ttataatgtg caaatcagcc tgaagctgtt tatgtatatg tgaatatccg taactagtac
     6541 gtatgcctcc ccggcataga caggtaagat tgcatagtag ttttgtcgtg ttttattttg
     6601 tgtttgtgtt gtgaataagc cttgtcgaga gacaaggctt attttttgta tattatatac
     6661 agaatctctg ttgtcaattc agtgtttttt cataagatgg gtaggcaatt cctttttctt
     6721 actaattgtt aactgacgtt atcatgtctg taacaatttg ttccaattgt agtattaatc
     6781 gttcaaaata gtcttttttg ttcaaaaaat gctatacacg gtaacaacta catgcaaatt
     6841 gtttatacat ttgcgttgtt gtttatgtaa ctattgggat gaacaaacca tagctgacaa
     6901 acgttaatag gtacgagtac atagctgatg aaagacgcga cttggctgac ttgttaatga
     6961 ggatacacgc gacttacaac ttagtattgg gaaaaataat taaggaaata tagaataaaa
     7021 agattgctta tgtcacagat tgtcggacat atctcacagg taatcgggcc tgtagtagac
     7081 gtctatttcg aaggaacgga ggcagaaatg atgttgccga gtattcacga cgcactggaa
     7141 ataaaaaggt cgaacggcaa aagactgatt gtagaggtac agcagcacat tggtgaaaac
     7201 acggtgcgta ctgttgctat ggacagtacg gacggcctgc agagaggaat gacagtgcat
     7261 ccgctgggag gccccatcac catgccgata ggtacacaaa tcaaaggccg cctgatgaac
     7321 gtagtgggcg actctatcga cggcatgaag gagttggacc gtacaggtgc ttatcccatc
     7381 catcgcgacc cccctaagtt tgaagatttg actaccgtac aagaggtgct ttatacaggc
     7441 atcaaggtta tcgacttgct ggaaccatat agcaagggcg gtaaaatcgg tctgtttggt
     7501 ggcgccggtg taggcaagac ggtgcttatc caagagctca ttaataatat tgcgaagaag
     7561 cagcacggct tctctgtgtt tgccggtgta ggagaacgta cacgtgaagg caacgacctg
     7621 ctgagagaaa tgatagaatc cggcgttatc cgttacggag aagaattcaa gaaaggtatg
     7681 gaggaaggcc attgggattt gtccaaagta gattatgacg aagtggccaa atcacaagtg
     7741 tctttgatat tcggtcagat gaacgaacct cccggtgcgc gtcagtccgt ggcattgtct
     7801 gggttgacgg tggccgagtc cttccgtgac atgggagcgg agacggacgg tccgcgtgac
     7861 attctgttct tcattgataa tatcttccgt ttcacccaag ccggttccga ggtttcggcc
     7921 ttgctgggcc gtatgccttc tgccgtaggc tatcagccga cactggcaac ggaaatgggt
     7981 gccatgcagg agcgtattac ctctacaaga aacggctcca tcacttccgt gcaggctgta
     8041 tatgtgcctg ccgatgactt gacggacccg gcacctgcca caacgtttac ccacctcgat
     8101 gccaccacgg tgttgagtcg taagattact gaacttggta tttatcctgc tgtggacccg
     8161 ttggaatcta cttcacgcat tctcgaccca cacatcgtgg gggtagaaca ctacgaagtg
     8221 gcacaacgtg taaaacaaat attgcagcgc aacaaggaat tgcaagacat tatctccatc
     8281 cttggtatgg aggaactctc tgatgccgac cgtacgttgg tgaaccgtgc acgtcgtgtg
     8341 cagcgtttcc tttcacagcc gtttgccgtt gccgagcagt ttacgggtgt cccaggtaca
     8401 atggtttcca ttgaggacac tatcaaaggc ttcaagatga ttcttgacgg agaggtggac
     8461 tacctgcccg aacctgcttt cttgaatgtg ggaaccattg aagaagccat tgagaagggt
     8521 aagaaactac tggagcaggc agggggaaaa acgattaaaa attaaaagtc tgggagcttt
     8581 gatgatgaaa aagttgcatt tgaatattgt ttcaccggag aaggaactct tcaacgggga
     8641 agtggaaagt gttacattgc cgggcactat gggctctttt tctatcctgc cgcagcatgc
     8701 accgattgta tcatcgttgg gaacggggaa attgatttac gcaacggacg gtgaggaaca
     8761 tgagttggat attcaaagcg gattcgtgga gatgagtaac ggaagggttg ccgtctgtat
     8821 agaacagcaa taggctatta aaaaattaaa aattaaaaaa tagaggttgt tggcgtgact
     8881 attactaaga gaaactactt attgcataca gcgctcttga cggtattgat aggaattgta
     8941 ggcggttggg cgtatttttc gataaatccg catcactatt tcggcggtta tccgctgatt
     9001 ccgcttttct tctttgtttt cggagtattc atgattaata tgaccgaaag ctgccgtcac
     9061 cggatgccag gacgaatgtt gcagatttat ctgctgatgc gtgtgatgag aatgctggtc
     9121 tccatgattg tgatgctgtt ttattgcgtt gcagtacgtg aggaagccag ggcgtttttg
     9181 ttgacgttta tagccaacta tctgatatat ttgatttatg attcctggtt cttcttcact
     9241 tttgaggcga atcggaaact gaaaaagaaa agtaacaatg aaaagattgc gtaacatact
     9301 gactgtaatt ctgctggcac tgggcatgtt gctacccgcc acggtgcggg ccgagaatac
     9361 ggtggacgtg aaggagattg tcttcgggca tatcggcgat tcttacgaat ggcacatcac
     9421 gacgtggggc gaaactcacg ttacgattcc tttgccggta atagtgcata gctctaccac
     9481 cggatggcat gcctttctat cctcacgtct ggaggagaac ggtggaagtt atgaaggctt
     9541 ttccatcgct cccgcaggaa gcaagtacga aggcaagctg gtggagtatg atgccaccgg
     9601 aaacgaaata cgcccgttgg acatctccat cacgaaggtg acactggctt tgctcatcaa
     9661 cagcgcattg ctgcttctca tcattttgag tgtggcgcac tggtatcgca agcacccgca
     9721 gggaagtgcc gctcccggtg gtttcatcgg gtttatggag atgtttatca tgatggtgaa
     9781 cgatgatatt ataaagagct gtgtcggtcc gaagtaccgt aaattcgcac cttacttgct
     9841 gacggccttc ttctttattt tcatcaacaa cattatgggg ctgattcctt tctttcccgg
     9901 aggggccaac gtgacgggaa atatagccat tacgatggta ttggccatct gtactttctt
     9961 ggccgtgaat atctttggaa ccaagactta ttggaaagat atcttttggc cggatgtgcc
    10021 ctggtggctg aaggtaccgg tccccatgat gccgtttatc gagttcttcg gtattttcac
    10081 caaaccgttt gctttgatga tacgtctttt tgccaatatg ctggcagggc acatggcaat
    10141 gctggtgctt acctgcctga tattcatctc ggccagtatg ggacctgctt tgaacggaac
    10201 gctgaccgtg gcatcggtgt tgttcaatat ctttatgaat gcacttgagt tgttggttgc
    10261 ctttatccag gcatatgtgt tcaccatgct gtcagccgtg ttcatcggtc tggcgcagga
    10321 agagcataag gagaaggcgg tgaagtgata cgattattgg gaatataaat attaataaaa
    10381 ataaccattt aaaaactgaa agttatgtta ctatctgtat tattgcaagc tgctgcggca
    10441 ggtgtgggag ttagtaaact gggtgcagcc attggtgctg gtttggctgt tattggtgct
    10501 ggtgtaggta ttggtaaaat cggcggttct gctatggagg ccattgcccg ccagccggaa
    10561 gcatccggag atatccgtat gaacatgatt attgccgctg ccttgattga aggtgttgct
    10621 ttgttggcag tagttgtgtg tttattggta ttctttttat aatgtacaat ctaccattta
    10681 ccatttacaa tttgtccgtg cagcatcacc gcgcagccaa attgtaaatc gtaaattgtc
    10741 aaatagtaaa taaaattatg tcattgttat tacccgatag tggtctgctg ttctggatgc
    10801 tcctttcatt cggtgtggtg tttgtggtgc ttgccaagta cggttttccc gttatcacca
    10861 agatggtgga aggtcgcaag acctacatcg accagtcttt ggaagtggca cgcgaagcaa
    10921 atgcccagct ctccaaactg aaagaggaga gtgaagcgtt gattgctgct gccaacaaag
    10981 aacaaggacg tattctgcgg gaggcgatgc atgagcgtga caagattatc gtcgaagcac
    11041 gcaagcaggc ggaagccgcc gcgcagaagg agctggacga agttaaaaag cagatacagc
    11101 aagagaagga agaggccatc cgcgatattc gccgccaggt ggcagtcttg tccgtagata
    11161 tagccgagaa aattatccgc aagaatctgg acgagaaaca tgagcagatg gagatgatag
    11221 accggatgtt ggatgaagtg ctggccgcaa gtaaaaacaa ttaattctca aagaaatgga
    11281 tataggaatc gtttcgatgc gttatgcgaa agcattgatg gaatatgcca agagcatggg
    11341 ggcagaagat actctgtaca aggagttttg tatgctcgac cgtagcttca ggaaacatcc
    11401 cgatttgcgc atggcattgg aaaaccccat cctgacgata cgtgagaagt taacacttat
    11461 ctgtaccgct gctgtggggg atgctcctgc gggccgtgag tttgcgcgtt tcatgaccct
    11521 ggtgttgaag aaccggcggg aaaactttct ccagtacatc tgcctgagtt ttctggattt
    11581 gtaccggaaa gacaagcata tcggtgtagg aaagctgata acagccgttc ccgtcagcca
    11641 ggaagtgcgg gagcgtattc atgacagtgc ttcctccctg ctgcatgcca gcatggagct
    11701 gcagactgaa gtggatccct ccattgaagg tggttttatc ttcgacatca acgacttccg
    11761 tctggatgcc agtattgcta cgcagcttaa gaaagtgaaa cagcagttca ttgataagaa
    11821 tagaagaatc gtgtgattta cgatttgaca atttacaatt tacttattta atagtcttgt
    11881 gatgcgtaag ttgtagaggt caaacagtat atgattcggg ttctttcaaa tagtaaatag
    11941 taaattgtaa aatagtaaat actaagatgt tgtctgaaaa tataaaagta agcgaagtct
    12001 ccgatattct ccgcaagcaa ctggaaggga ttgacacccg cgtacagttg gacgagattg
    12061 gcacggtact gcaagtcagt gacggtgtag cccgtatcta tgggttgcgc aatgccgaag
    12121 ccaacgagtt gttggagttc gacaacggca tcaaggccat tgtgatgaac ctcgaagagg
    12181 ataatgtggg tgctgtgttg cttggcccta cggataaaat caaggaaggc ttcattgtaa
    12241 agcgtaccaa gcgtattgct tccatcatgg tgggagaggg tatgctgggc cgtgtaatag
    12301 accctctggg tgcgccgctc gatggcaaag gactgatagg cggagaactt tatgaaatgc
    12361 cgctggaacg caaggcgccg ggagttatct tccgtcagcc ggtgaatcag ccgctacaga
    12421 ccggtctgaa ggctgtggat gccatgatac ctatcggccg tggacagcgt gagctgatta
    12481 tcggtgaccg ccagaccggt aagacggcca ttgccatcga taccatcatc aaccagcgtg
    12541 ccaattttga tgctggtgat ccggtatatt gcatttatgt agccattggc cagaaaggtt
    12601 ctaccgtagc ttctattgtg aataccctgc accagtacgg tgcgatggac tataccattg
    12661 tggtggctgc tacggcggga gacccggctg cattgcagta ttacgctccc tttgcagggg
    12721 ctgccatcgg agagtatttc cgtgataccg gccgtcatgc gctggtggtc tatgacgact
    12781 tgtccaagca ggcggtggcc tatcgtgaag tgtctctgat tctgcgccgt ccgtcaggac
    12841 gtgaggccta tccgggtgat atcttctatc tgcactcccg tttgttggaa cgtgcggcga
    12901 agattatcag ccaggaggaa gtggcacgcg agatgaacga cctgccggac agtctgaaag
    12961 gcaaggtgaa aggtggcggt tcgctgactg cattgcccat tatcgaaact caggcaggag
    13021 acgtgtctgc ctatatccca acgaatgtga tttcaatcac tgacgggcag atattccttg
    13081 atacgaacct cttcaaccag ggtaaccgtc cggccattga cgtgggtatc tctgtgagcc
    13141 gtgtgggtgg taatgcccaa gtcaaggcta tgaagaaggt ggcaggtaca ttaaagattg
    13201 accaggcaca gtaccgggag ctggaagcgt ttaccaagtt cagtggcgat atggaccccg
    13261 tgacggcatt gaccatcgac aagggacaga agaatacacg cctgctggta cagccccaat
    13321 acagcccgat gccggtagaa aagcagattg ccattcttta ttgcggcacg cacggcttgt
    13381 tgaggaatgt tcctttggac aaggtcagcg agtttgaacg caacttcctt gagtctcttg
    13441 agatgaacta tcgcatggag gtactcgacg ttttaaagac gggtgccatc aatgacgatg
    13501 tctgcaagaa gattgaggag acggcagagg cggttgcaag gcaattcatg taatttacga
    13561 ttggacgatt tacgatttac gattggggct actctatatg gtaagtggta aatcggctgc
    13621 aagcaaaagt aacttcaatc gtaaatcgta aataattaaa tcgtaaatag atatatgtct
    13681 tcactgaaag aggtaaaaaa tagaataagc tccgtcaaga gtacacgcca gataacatcg
    13741 gctatgaaga tggtggcatc tgccaaactg cataaggcgc aggggcggat tgagaatatg
    13801 ctgccttatc aacggaagct gaatgagatt ctgacgaact ttctgcgtac ggatgcttcc
    13861 ttcgagtcgc cctataccga gaaaagaccc gtgacgagag tagcggttgt ggcgttttcg
    13921 tccaatagtt ccttgtgcgg tgcattcaac tcgaatgtgg cgaagatgct ggaacgggct
    13981 ttggaagatt accagtcgct gggcaaggag aatattctga tatatcccgt tgggagaaag
    14041 atggaggaag ccgtcaagaa aatgggatat gtgccgcaag gcagctacca ggtgatggca
    14101 gacaagcctt cgtacgttga agcgtatgag ctggcagaga agttgatgca tgagtttgtg
    14161 gaaaagcaga ttgaccatgt ggagctgatt taccatcact tcaaatcgat gggttcgcag
    14221 gtgctgctcc gcgagaatta tctgcccatt gacctgacgc aagtagcgca ggaggcggca
    14281 gaagatgtac cggaggatgc ccgcagtttt aataatgatt acattgtgga accttccgtc
    14341 ggcgaactga tagcggaact tctgccaaaa gtgttgagtc agaagatatt taccgtgctt
    14401 ctcgattcca atacttcgga acatgctgcc cgtatgctag ccatgcagac ggcgacagat
    14461 aatgccaacg agttgattca agatttgacg aaacagtata acaagagccg tcagcaggcc
    14521 attacgaatg agctgctcga tattatcggc ggtagcttga aatagtccgg attgccccgt
    14581 aaagggcttt ctcaggatgg gtacaaataa atggaataat aggacaagga taacgaaata
    14641 agcgttatct ttgtcctatt atcatatatg gctactgatg aaatccgtat cattctgaga
    14701 gagagcggat tggttgaata ataaacatat caatggagaa taatcccgaa atagcgcttg
    14761 catggcaatt cattgaaaac acaggcactc atcttttttt gaccggcaag gcaggtaccg
    14821 gtaagacaac tttcctgcga aaactgaggg cagagagtcc gaaacggatg attgtacttg
    14881 caccgacggg aattgccgct atcaatgcag gcggtgtcac catccactcc tttttccaag
    14941 tacctttcgc tccttatgtg cccgaaagct cattcagcgc agatggcaag gcaacctacc
    15001 gttttcgtta cgggaaagag aaaattaaca ttatacgcag catagattta ttggtcatcg
    15061 atgaaatcag tatggtccgt gccgacttgc tcgattcggt ggatgccgtc ttgaggcggt
    15121 tccgcgaccg gaacaaaccc tttggcggcg tgcaactgct gatgattggc gacttacagc
    15181 agctgtctcc cgtagtgaaa gacgatgagt ggcagatgct gcgcaaatac tatgacacgc
    15241 cttatttctt ctc
//
