LOCUS       gnlProkkaBLCAAMBO_11   14111 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BLCAAMBO_11.
ACCESSION   gnlProkkaBLCAAMBO_11
VERSION     gnlProkkaBLCAAMBO_11
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 16:33:59
            Original ID  :: gnl|Prokka|BLCAAMBO_11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67454
            Orig. end    :: 81565
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14111
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10267]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14111
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14111
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             719..1567
                     /locus_tag="ctg11_53"
                     /transl_table=11
                     /translation="MNISEFNINDEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANALLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSKTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGYT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
     CDS             complement(1642..2418)
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 2e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_ctg11_54_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 82.4; E-value:
                     5.9e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_54"
                     /transl_table=11
                     /translation="MSNENKTIHDFEFNLICDFFSNMERQGPGSPEVTLKALSFVDGLT
                     DESLIADIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNLVAKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSLLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        complement(1984..2265)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_54_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-11"
                     /label="ctg11_54_oMT.1"
                     /locus_tag="ctg11_54"
                     /protein_end="145"
                     /protein_start="51"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(2652..2957)
                     /locus_tag="ctg11_55"
                     /transl_table=11
                     /translation="MDCENCAARIATVNNDDELREKTAKEWSVLNNTPEITPETIHCMG
                     CRADGVKFTYCSDYCAIRKCVYEKGFNTCGDCKELDTCQVVGAVLQHAPGARENLY"
     CDS             complement(3121..3273)
                     /locus_tag="ctg11_56"
                     /transl_table=11
                     /translation="MVGDSSLLQNSGVSGRWKQILLPPFQVASTAGQMPMDRGMQEVGG
                     SVEAK"
     CDS             3850..4176
                     /locus_tag="ctg11_57"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWRKELRTREKTKQTPCKLPDRVSRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             4541..4756
                     /locus_tag="ctg11_58"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             4770..8348
                     /locus_tag="ctg11_59"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGRKGNITVNATFEG
                     AGTDTRTTVNDKYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASND
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFN
                     TAPTTSTAAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVGTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             8595..9521
                     /locus_tag="ctg11_60"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             9548..9988
                     /locus_tag="ctg11_61"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             10001..10267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_62"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.2e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.4e-15, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             10276..11439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_63"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.2e-45, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             11462..13132
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.6; E-value:
                     3.6e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_64"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(13177..14088)
                     /locus_tag="ctg11_65"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
ORIGIN
        1 ataacgcggt tctataatca tcagattatg ttccatgtcg aaagaccatt gaaatatctg
       61 ggtgcggctc agcgcaatat tcagcaaatg cttctgtgtc cgttcttcca acacattcct
      121 aaaatagagt acaatcctca ccaattgtcc atcttcatga attcccacca tagcaccttg
      181 tatcagaaaa ctgataccac tctttaattc acgtataaag caattggtat ccaagggaat
      241 aatccgtaca tccctctccc gaagttgcag caaaagggct tccaacacat tctttttatc
      301 acataccact tccaataagt cagtgatatg ccgccctatc acatgctcat tcaattggag
      361 ttcattcatc acctgctgat tcagacgcca gatacaatct tccaaatcaa tcataataat
      421 gctgacgggc catgagttga acaactgctc ggagatggca tttattatac gtacttcttg
      481 aggaacattc ggattcatca gaattggttt atcatacaag gagcaaagtt cgggctaaaa
      541 tgcttatgcc acaaacaaac ccttataaat caatattcca ttttaatatg tatatattct
      601 attattcaca actttacctt atttaacaga gataagttga gcgtaatatt gattttaact
      661 gttacctctg tcatttatac attattatcc cccatttttg cgtcttaaaa tctccaacat
      721 gaatatatcc gaattcaata taaatgacga gttcattgcc tgcaatcata tcacaaccaa
      781 tgaactgaat ccgctagtgg aaaagccata ccacaccaag gccagtatct tcgctctatg
      841 caccaaagga gttctgaaaa ctatcataaa ccatactcaa ttcagggttg aagctaacgc
      901 cctcctagtt attcctcccg agaccttcgt acaattgcta cacacgtcag acgatgctga
      961 aatatatgtc gtcatatttt cccaacaact tatccagagt tcaggggccg gcaaggtcat
     1021 gatggataag tttcacatta taggcaaaca ctatattttt cctctatcga aaacggactt
     1081 ccagctttat gccgagttca tgacctattt gtcacacctc taccaaagaa cagaaagccc
     1141 ctcaagtcta gtttcattgc aaactctact gacctatctg ttacaaggta tatccgaact
     1201 ctgtccggaa cgccctagaa taaaagagac tccgggcagc aggcatttca accaataccg
     1261 catttttatc cgattggtac acacagacta tgtccgggag catcaagtgt cctattatgc
     1321 attgaaaatg aatatgagac cggcagctct ttgccgcctt gtcaaaaagg aatcaggata
     1381 tacagccatg gaaatcatca acaatactat catcatggat gccaaagcac aactttgtac
     1441 cgccaacact ccgataaagg atatagccgt gagtctaggt tttaataatg cggccttctt
     1501 caacaaattc tttaaacgtc atacgggaat acctcctcag aagttccgta catcctcaaa
     1561 acaataaaat ctactcaaaa cccaaaatgc ggatattctg tcctgagaat acccgcattc
     1621 ctcaataaga gaagtccgtc atcagcctac cttcttggca ataaagaaca cataaccgta
     1681 aaattcctta tacttgccgt acagttcatc ctcaatcatt tggagtaagc tgaactcttc
     1741 ggcaatttta ttaccggcat atttcttacg gaaaatctcc tgagccgcaa cctttgaagc
     1801 aaagtaatgc tctgtccagc aattctccgg cagaatgaat gtagcaacag ggagataacc
     1861 cgccttgtac aacttggcta ccagattggg aagtgtatcc atttcagaat aggcgtccat
     1921 ccagaagtca ttgatttccg caggacgttc gtccgtaaac catgaactct cggatacggc
     1981 aatataccct cccggtttca gatatttacg ccactccttc aagccacgtt caaagccgat
     2041 gttatagata gcaccttcac accaaatcat atccagctcc tcctcaccga aagggagggc
     2101 atccattgaa ccgacaattc cttttactct gtcctgcaag cccaactgcc ttgcattacg
     2161 gttgaagatg tcaataaagc cggggaaaag gtcaattccg gtaatctgtc ccggaacatg
     2221 gccagccaat accattgtct gaccacccgt tccacaaccg atatcggcaa taagggattc
     2281 atcggtaaga ccgtctacaa agctcaatgc cttcaacgtc acttcaggac tgccagggcc
     2341 ttgccgttcc atattggaga aaaagtcaca gattaaatta aattcgaaat cgtggatagt
     2401 tttattttcg ttactcattt tcttactata ttttgcatat acggaaagta tcacaacacc
     2461 ttcagcataa tatgcggatt aaacttgaat tataacaata gaaaaacact ctcgaaagaa
     2521 gttatccgag agtaaacgaa agggacaatc tgtgcatgga acacagattg tttacaaaac
     2581 caaatccgat ttaaatgtct ttgtcatact gcaaagataa gcaatatttt atttaatcaa
     2641 agattttacg gttaataaag attttccctt gcaccgggcg catgctgaag aaccgcacct
     2701 accacctggc aagtatccag ttccttacag tcgccacaag tattgaaacc tttttcgtac
     2761 acacatttgc ggatagcaca ataatcgctg caataggtaa acttcacccc gtctgcacgg
     2821 caccccatac aatggatggt ttccggcgta atttccggcg tattgttcag cacactccac
     2881 tctttggcgg ttttctctct cagctcatcg tcattattga cagtggctat acgggcggcg
     2941 caattttcgc aatccaaccc gcaacatgca attaattgtt tcatcacttg gttataacca
     3001 tttatgtgtt tctcatagca agcatttgtc tacctcctct ttatctgaat ttaagaggag
     3061 gcagacagcc atgctacaaa tatacggtta ttattgtgtg aatgccaaat taattttcca
     3121 tcactttgct tccacacttc cacccacctc ctgcatcccc ctgtccatcg gcatttgccc
     3181 tgcggtggaa gcaacctgaa aaggtggaag caaaatttgc ttccacctgc ctgaaacgcc
     3241 tgagttttgc agtaagctgc tatcccctac cataatactg catgcagatt acatgaatcg
     3301 gcaggttcgg ttttcctgca ttttcgggct tgtccttact gtgaagtcaa cagatatgga
     3361 gttggactgt aggggcatag taggagttat cgggagtcaa aggccgacta tgaataatgc
     3421 actctaatgt cttttacacc gttgtataat acgtttgcgc cttgtgcgca ataggttcgg
     3481 gctacgtact tcatccgcaa tagctctgga gttagtgacg cctaacggcc atgaacaacc
     3541 ctgcttacgg tcgtcaagcg atcgctttat ggccgaaagc agggttgttc atggccgtta
     3601 ggcgtcataa attccctatg ccacagcaga caaacaaagg gagaagagca aaggaatacc
     3661 tatgttttag ataaaaatcc acaagctttc actcgtgctc tccataggtt atgagagcag
     3721 gcttcgcgct ctgtgcgata aattcccatt tatcagcagg catactcact tacgaaactt
     3781 caattactta tataaattgt ttcagccaaa ggcagtacgg acatttgcaa aaatatggaa
     3841 agtcttatta tgaaaaattg ctatggcatc gacttccgtt cgtggcgtaa ggagctacgt
     3901 acacgcgaga aaaccaagca gacaccctgc aaactgccgg acagagtaag ccggagtttg
     3961 cagggtgttc tgtttaaagt atatcaaatc tctgttttaa ttttgcttaa aaagatttta
     4021 ttcagcttct tttcggtctg tcttcctctc tttattcgcc acatagccgc tatgctcctc
     4081 agaaaaacat cctcaaagac aatgcagaca gttactaaat atttgaagga gttatcggga
     4141 gttagaagtg ataactctcc taactcctat aaatgaaaga gacgtgagcc tttcccaaaa
     4201 aaaatagaga aacatagata cacttaaaca aaaaacaatt atctttgtca cgaatccgct
     4261 atagcgtagt gggtttattt acatattagt aagagcatta ttgaaattat cttctttatt
     4321 caaacttcgc aaatttgaaa atttccctga agataacaac aaggatgctc acgtctatgt
     4381 ttatatggtt ttctcccatc agggggatgg tatatacaca aacgacgtga gtgactgttg
     4441 tatatccagg gaaagggcaa tgcgaaggcc tgaataaagg atatacaaac atagttactc
     4501 acgttttttt tattgtttaa cctttaaata atttgtgtat atgaaacaga acacaccaga
     4561 cggtagagaa gcatacatca ctccgtctat cgaagttatc aaaatggaga atgaaggagt
     4621 cattgcaaca agcggcgaac cttaccatcc cattacgcgc tcctattcgg gcagcacctc
     4681 tacccatagc tacaattcgg catccagcag cgacttggaa gacctaatca atgacatctt
     4741 aaccgtagaa aactaagggg gacttcatta tgatgaaatt aagaaacctt atgcaagttg
     4801 cctgcatggc aactgctgcc ttgaccgcat tcagttgcag ccaagaggaa tttgaaaaca
     4861 gcgggcggaa aggaaacatc accgttaacg caacgtttga aggcgcaggt accgacaccc
     4921 gtactaccgt aaacgataaa tacaagattc tatggcaaga taccgatgcc ctagggttgt
     4981 tctgtagtaa tgcagaaagt aattatagca atacaaaatt agaatatgca agcggtgctg
     5041 gtcaaacttc cgccactttc aacggcagca agccaagcgg agaaacggct gtattctcca
     5101 tctatcctta ccaacaaaac atgagcgtaa gcggcaatac attgaccatg actctacctg
     5161 ccacgcttac aaattataac ggcagcagca atggcccgat gtatgccaag gtgacaaatc
     5221 ccgacaatct gagcgctctg tccttcaagc acatggcagc catgataaaa ctgaccgtca
     5281 acaagattcc ggcagaggcc actactttca agattattgc ctccaataac attgcaggta
     5341 cttgtacggt agacttaacc gcagcagacc cgatactgac ggtagcaagc aatggaagca
     5401 aggaaatcac tgcctccttc actgcttcaa acgatataaa atcgcgcaac ttctacattc
     5461 ctttgcccac aggtacttat agttccatca ctgcccaact gacgaatgga agcgacaagg
     5521 tatattttac caagacgctt aatgacaaaa tcttagggag aagagacata ttggtagtac
     5581 ctcctttgga ttgcgttgtt gtagatgcta caacccccag tgcgcttagt acagctttag
     5641 ctgattcaaa aaatctccca caagaagcac cgacagcagc aaccgtaacc gacattgcag
     5701 tcagcggcag cttcaatacc acttctggca gcaacgacgg catcgccatc ccggttttac
     5761 agaactcgga catcaacctg acgttcaata cagccccaac gaccagtact gccgctccgt
     5821 tgacgctgac cgacaagacc aataccagcg taagtgctcc cgccgccact gccaccaaca
     5881 gtgtatcctt ggctgtaccg gaaaccacag cagagcaaga agctccttct gtagccatca
     5941 ccatgccaag caccaccgtt acattggcag cagtaggcaa taaagccact tacaatgaag
     6001 tgactgccac taccgcccag cagacattga ttatcaatgc aggcgtcacc gtaaagaagc
     6061 tgactgtaaa aggcggtaac ttgaagatat atggaaaggt agaacaattg gtacacgatg
     6121 ccggcaatac cacaatctat ataataaaag gaactgaagc atcacttccg gcaacaatcg
     6181 acagcaaatt tgtagttcaa tccgacgtgg cagtcctaaa gaccgctttc gccaacggcg
     6241 aagattttaa attgtccgcc gatgccgaca tcacagggca aagcgtcagt gtacccgccg
     6301 gaaagtccgt ggttcttgac ttgaacggat atacactgac tgccgacaac agcgcaacag
     6361 gcaaaatcat cgtcttgggc aagatgacac tgaaggacag ctctaccgag aagaaaggca
     6421 agatagttgc cagccaggat tatacagcgg cttcttataa tggcagtctg attgaaatag
     6481 ccggtgaaga tgcctccatg accatggaaa gcggcaacat cagtgcagtc agagagactc
     6541 cggacagtaa cggccaatat ggcgtcggag tgacggacgg tggagacttc accatgacag
     6601 gcggcaagat agaagccgga tggtttgcag tggcaggcaa cggcaattac aagacgcaga
     6661 actccatcat caacatcaca gacggagaac tcatttctac tgctgactat gcagtctatc
     6721 tgccccaatc cggcacaacg accatcagtg gcggcaaggt ttatggtgcc gcaggaggtg
     6781 tatgcatcca acgaggcact ctgaatgtgg aaggtacagc cttgattacc agtaaaggca
     6841 caggtagcac cggcaactgg ggcgacggta ccggaggact ggactgcgcc gccatcaacg
     6901 taagtggagc atatggcatt gccacagtaa acatcaaagg cggtacactg attgccgaag
     6961 caaagtcact catcacagaa ggcaccactt atacaccggt catcaacgtt accggcggta
     7021 cattctccga cccaagcgcg ctgaagtaca tgaaggcaaa tgcaaatgtg aacataaagt
     7081 tgaccgccga caagacctgc ccgggattca agaccacaag cggacaaacc ttgacgatgg
     7141 acttaggcgg caagattctt acacttgctg acccgaccgt aggttccacc ggcaccgaaa
     7201 cgaacagctg tcaattactc gaaggttcaa acgttacttt caagaacgga acgctgaaga
     7261 gtgacaacaa caaaatcatg attcagaact actgcaacct gacattagat aatatgacag
     7321 tagaagacac aaatgcccaa tacgtagtaa gcaacaattg tggcaacata agcatcaaca
     7381 ataccactat caacgcagga agcaatgcga atcaatttgc attcgacgta tgcggctatg
     7441 caaagtacac tgctggagtc acggttacgg taagcggtac gagcgtcatc aatggaaaag
     7501 tggaaatttc caagagtgca ggaaataccg aacttatgaa gctgaatatc acaagcggta
     7561 ctttcaacgg tgacttaaag gtagatgcat ccgtgggaac cgaaaatgcc caaagtatca
     7621 tctctgtttc cggcggtaca ttctccgacc caagcgtact gaagtacatg gcaaccaacg
     7681 caactgtgga tataaaactt ctctcaaata tcaacatcgc caagacggag cttgccacag
     7741 gctacatatt gaatgctgca aacgcaacgg caaacttaaa cctgaatggc cacgacatca
     7801 tcaattcctc agaaacagct gatgccactc ctttcacaca aatctttact gtacagaacg
     7861 gaacactaaa catttcaggc aacggcaatg tgaagtgcga tgcatctgct acagcgaaag
     7921 acgatggtta tcgcatggta attgaagccc gaggatacgg gacagtaaat attcatggcg
     7981 gttcttacta taacacccag aaactgaaca cccagataga cctgatttat gcaagagaga
     8041 atgggaaaat caatatctat ggaggaacat ttgaatccgg caaatatggt acacccaaca
     8101 acgacacgga tggcagatac tgggtactga acttaaagaa tacagacaag aacactgcca
     8161 gcatccaggt gtccggtgga acgttcatca atttcaaccc ggcaaatccg aatatggacg
     8221 acaatgagtc ctatttggta acaggctacg aggttacccg tgacggcagt gtatatacag
     8281 cagcccacaa agtcggtgat gggaggaaag aatatattgt tggccaaaca agtcaggaga
     8341 accgataagc caaattctaa gaaaggaagc aatatatcct cgcaaaccaa acgaagagat
     8401 atcggaatcg ccttattact atcttttaga tgcggcggac agcggatttt cttttataga
     8461 tctgcgtcct ccgcgtctaa agaatgacaa caagacagtt gaaaaatctc tcaaatcttc
     8521 ctcattcaca caaacattca ttatttttct gagtagccca aagtatcatg aataacaact
     8581 aacaatcaaa acatatgaga atacagatat tggattatca agtaggaccg cacacctttc
     8641 gcatggtgaa accttccgac ttcaatatat tcaaggcgct gccttcactg attccgttca
     8701 tcacgacaat agacacgact caaaaagtaa tctttgaaac agagatagac gatgacgaaa
     8761 caacgacaaa acgaaccata gcgaaaactc ccgatgatat atgtttcaac tgggaagatg
     8821 ccgattgcat cattcgccct ttgccccaca gctcacacct tgtatccatc accccacgga
     8881 aaagcgggaa aaactattgg atggagtgca acgataactt caggcaatgc ttcatccacc
     8941 taccggcctg caggacagaa acaccggctc cggaaaacga aacgaacttc gtactgaaca
     9001 acttcttgat gatgctctat gccttcaatg ccgcccgcca ccatacactg ctgatgcatg
     9061 cctcggttgt cgctactgaa acaggcaaag gctacctctt cttagggaaa agcggcacgg
     9121 gcaaaagtac gcacaccggg ctctggctgc aacagttctc ggactgccat ctactgaacg
     9181 atgacaatcc gatagtacat gtggacagcc tcggcaagca agccactgtt ttcggttctc
     9241 cgtggagcgg aaagacacct tgctatcgga aagaatccat gaccgtaggc gccttcgtcc
     9301 gcttggaaca agcaccgcag aatgaaatag agcaagagag agcagcacat gctttcgcca
     9361 ccctcctccc ctcctgctct tgcctgaagc agaacaagga aatctataac gccattgtcg
     9421 ccactgtgac ggaacttgcc acgctggcac ccgtctatca tctgaaatgc ctgcccgacc
     9481 gtgaagcgac ggaactttgc agaaagacgg tagaaggata agttatgaat gatgaactga
     9541 acagccgatg aagaaaagca ttcccaacga gatattgctt cccgaagtgg cgcgtctcat
     9601 caaagaggga catacagtaa ccatcaccgt gcggggcaac agcatgaatc ctttcttagt
     9661 ggaccgccgt gaccgggtga cactgggcga tttcaccaca gaacagctgc aaccgggcgt
     9721 caccgtactg gcacgcgacc tgacggaacg catcgtcttt caccgcatca tccgtcggaa
     9781 cggagacata ctcatcctgc aaggcgacgg caacctcgcc cagaccgaag aaaccgacat
     9841 cggacgggta atgggcgtca tgaccgaagc catgcgaaaa gacaaacggt acaccgccga
     9901 cggcaaagtc tggaagctct actcctactg gtggatgaag ctaaaccccg ctcgccgctg
     9961 gctgctcgcc ctgttcagaa gaatataaaa caaaataacc atgaaaatca aacaaggatt
    10021 tatcctgcac cggataggcg atgactacat catcatgcaa gacggctcgt cgaacgtgga
    10081 cttcagcaaa gtcatcagcc tgaaccaaac ttccgccatg ctttggcaag agatagaaaa
    10141 caaagagttc gatacagaca gcgtgacaga agccctgacc agccgctatg atgtagataa
    10201 cgaatcggcc cgtcgcgatg cgcagaagtt tatcgactcc ctcgaccgcg aaggaatcat
    10261 agaataagga cggatatgca acacgctttc ttttcattgg tacgctccgg cctgtggggc
    10321 actccggcag accgacaact cttccggtcg gtctcgccgg acgactggga aaccgtgtac
    10381 cgcatggcaa actcacaagc cctgcttgca ctgacttttg acggcataag cagtctgccg
    10441 gccgaactgc gccctccacg cgtcctctat ctgaaatggg ctgcccggac tgcacagata
    10501 gaacaagcca acaaacgcct caaccagctt ctgcccgaac tcaataccct ttaccgggaa
    10561 gccgggctgc atcccgtact gctgaaaggg caaggcatcg gcaccaacta ccgcactccc
    10621 ttgcaccggc aatgcggaga catcgacatc tatttaggaa aacaagggca acccatagcc
    10681 aaccgcctcc tgctgcaaca aggcgccata gtcgagggag aagcgtccga caagcatgct
    10741 agctacagtt tgaaaggagt acacatcgag aaccaccgca tcatcctccg gctgaacagt
    10801 ccgcttgcca accggtactt tcagcagatt atcagaaaat ggtacccgca ggaaacagac
    10861 tatgccctat tctccgaaac cgggaaagag gactcgaagg ccgtcagtat cgccatacct
    10921 ccggccacct tcaatgcact ttatatcttc ctgcatgcct ttgtacattt cctgaacagc
    10981 ggaatcggcc tgcgccagct atgcgactgg acttgtctgc ttgccaatcg ccacaaagaa
    11041 atagatgcca ccaccctgct tcgccagttg caggacctcg gactattgca tgccgcacaa
    11101 gcattcggct acattgccgt cacccgactg ggattgcccg ctaaccggct tcctttcccc
    11161 ttggaaggca ccaagcagat aggagaacaa ttattggaag acatcctgtc taccggtaac
    11221 ttcgggcaac atgataaccg catcaagcca cgccccaaag gatattgggc aggaaagtgg
    11281 tacaccttct gccgcgccac ccgacgctgc aacgaactgc gtcaatttgc accgtacgaa
    11341 gcactctggt atcccgtgac tctgataggg ggaacgatag ctatacaaat aaaccgatca
    11401 aaaggagtaa aagacaagaa agcaaggaca aagaaataaa agaacccgga aaataaaagg
    11461 aatgaaaaag caacagaagg acaaaaaagt gaaaaaggac agacgtgaaa aacttaggta
    11521 tattcgagag gtatctgccg aacaacgcgg acgtatcctg ctaagttgcc tcaccggcat
    11581 tctgggcgtg gcctttgccc tagcctttat ctatgcaacc aaacgggtga tagacaccgc
    11641 taccggaata acagacgaca acctgacgca tatcgccgtt ctcaccgttg tcctgctgac
    11701 tgcccaatta ctgtgcggag ctgctgacac ttggataagt acccgtatgc agatagagac
    11761 gggcaacgcc cttcgccacc gcctcttctc gcgcttactg caaagccgct ggaacgaatt
    11821 ggagcgtttc cataccggag acgtagtgaa ccgggtagaa caagacacca ccgccatcgt
    11881 cacattgctc acctcttctg tcccggcatt catcgtcacg agtatacaac tgctggcagc
    11941 ctttctattc ttctactttt tagacccttc actgccatgg ctgattgttg ccatcctgcc
    12001 cgtctttcta tcaggcagcc gtttctatat gcgacgaatg aaacgctata cacatgatat
    12061 tcggaacagt gacggtcgca tccagtccgt catacaagag agcctgcaac atcgcatagt
    12121 gattaaaaca ttggaacaag gcgaacggca tctggacaaa ctcgatgact tgcaagacat
    12181 gctccacagc caagtcatgg gacgtacccg tttctcgctt tctgcccaca tgttagtggc
    12241 ccttgccttt tccggcggat acctcacggc ttttctttgg ggagccgttc acctcagcgc
    12301 aggctgtatc accttcggaa cgatgaccgc ctttttgcaa ttggtaggaa aagtccagcg
    12361 tcccgtgttc gacctctcac gcctgatacc ttccgtagtc aatgccctta ccgccataga
    12421 ccggctattg gaattggaaa gactgccggc agaagcggat ggtgacagca tattcctcgc
    12481 ctctaccccg gaactggaac tgaaagacgt gacttttcgc tacactcccg atgaccgtcc
    12541 ggtattcagc cgcttctcct gccgtttccc cgccggtagc tgcatagcta tagtcggaga
    12601 aacaggaaaa ggaaagacaa cgctcatccg gctattgttg gcactggcaa cgccacaaga
    12661 gggacagata ctcttgatac ccgccaaaca tccacttgaa accaatcata ccgtctctcc
    12721 gcaaacccgc aagaacttcg tatatgtccc gcaaggcaat acccttttca gcggaactat
    12781 ccgtgacaac ctgctgatgg gaaacccaca agcttctcaa gaagccatat atcaagccct
    12841 gcaaaccgcc accgccgact tcgtcttcca ccttcccgac ggcgtagact ccccactcag
    12901 cgaacgaggt ggtggactca gtgaaggaca agcccaacgc atcgccattg cccgcgctct
    12961 gctacgcccc ggaaacattc ttcttttaga tgaagccact tctgccctcg accccgacac
    13021 ggaacggctg ttaataaaaa acctgcgcag agactgcgca ggcaaaacat gtatcttcgt
    13081 cacccaccat ccggcagtag cggaggcatg cgaatctatt gtccgattat aatcagagaa
    13141 taagccccaa cgggtatctg cctttggtta acaaactcag aacagcttcg caggatactc
    13201 gcccgcatcc accaaagcct gaatcttgtc gactacactc tgacggtctt cgggataagt
    13261 cacaccgaac cacttgctgg ttgtatcaag cacttcgcag gtagcagtgc catcgttaat
    13321 cagcttatcc accatcagcg ggatgaagaa ttcgcttttc aggttctcca tattcttcgg
    13381 gtcgctcaag aaactcttga aaaactctgc actgtaagca aaataatcgg gagtgaaacc
    13441 ccagaagttc atgctgaccg gagtcgtctc gggagtggca gtccattcac cgttatcgtc
    13501 gatgtacttc acctcaccgt ccatgcgctg aatcttggta cgttccacta cggaagtcag
    13561 caggttgttc gcatccgttc cacacaatcc acgggatacg gtaccgctct cgctcaacgt
    13621 attgccgatg cggaagccta ccatggaata tacgtttttg gagccttcgg gaagggctgc
    13681 aaggaatttg cccattacct ggaaggagtc acgaccgtag aaatcgtcgc aattgataac
    13741 agcaaacggt tcctttatta catcggcacc catcattaca gcatggttgg ttccccaagg
    13801 tttggtacgg ccttcggggc aggtgaagcc ttcaggaagg tcatctatgg actggaatac
    13861 cagttcgcag ggaatatggc cttcgtattt ggaaataatc ttgtcgcgga agtcctgttc
    13921 aaaatcttta cggattacga aaacgagctt gccaaaaccg gcattgatgg catcgtaaat
    13981 agaataatcc atgatagttt cgccattcgg tcccaatccg tccaattgtt tcaagccacc
    14041 ataacggctg cccataccgg ctgccaataa gaataaagtt ggtttcatat tagttattat
    14101 ttaaaaaggt t
//
