LOCUS       c00195_gnlPro..         3712 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKHPODJK_195.
ACCESSION   c00195_gnlPro..
VERSION     c00195_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:08:15
            Original ID  :: gnl|Prokka|FKHPODJK_195
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3712
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..81
                     /locus_tag="ctg195_1"
                     /transl_table=11
                     /translation="ASLRAYARLVSSADKGAVRIVDDNEE"
     protocluster    1..3712
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[95:3500]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      96..3500
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3712
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3712
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             96..1850
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.8e-48, bitscore:
                     150.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSQTLRPEERRAASDPSMTGSKALIESFLQEGVETVFGYPGGA
                     IIPVYDALYDYRDRLRHILVRHEQGAVHAAQGYARVSGRVGVCLVTSGPGATNTVTGLA
                     DALMDSTPLVLVTGQVGSALLGTDAFQETNFIGITQAVTKWNCQVKRTEDIPAAIAKAF
                     YIARSGRPGPVVVDITKDAQCGTAPFRYEKITSIRSYLPAPAPDAERIAEAARLIDQAR
                     RPLVMVGQGVILGNAEAELRALLDKSGMPAASTLLGLSALPTDHPQNVGMLGMHGNYGP
                     NIKNQECDLLVAVGMRFDDRVTGNPAHFGANAKVIHLEIDPAEIGKIIPADVAVVGDVK
                     RSLPLITEXXXXTERIRKRNHSQWIAGFRACDQIEYEAVIRKAVHPAEGRIRMGEAVAA
                     VARAYRNDAVLVTDVGQQQMNAARYFGFRRTRSVVTSGGLGTMGFGLPAAIGAKLGAPD
                     REVVLFAGDGGLQMTIQELGTIFQSKIPVKIVLLNNSFLGMVRQWQELFYDRRYSFTEM
                     VNPDFGLIARGNGLSYRCVERREELDEAIAAMKASEGAFLLEVRVEGEENIFPMVPAGA
                     PVSEIRFE"
     CDS             1864..2415
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_3"
                     /sec_met_domain="ALS_ss_C (E-value: 9.8e-20, bitscore:
                     59.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQEYIITVFSENKVGLLSQITTVFTCRDVNIESLTTSESALQGI
                     HKFTIVVRTTPDQVDKLVRQVEKKIDVLKTFVYTPDEVVQQEIALYKVTRSRGVEQLVR
                     EHNVRILEIDEDYIVVEKTGHKADTQALFRLLQPYGVQQFVRSGTVAIIKSRRELLNEY
                     LEEIDRLRAESDEEGSKSEK"
     CDS             2454..3500
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg195_4"
                     /sec_met_domain="IlvN (E-value: 3.9e-47, bitscore: 148.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.6e-46, bitscore: 145.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKINFGGVEENVVTREEFPLEKALETLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFRVIVGQREGSASWDKAVADGWVPGQTLFGIEEAAERATIIQYLLSDAGQI
                     AVWPSIKKHLTPGKALYFSHGFGITYKERTGIVPPADVDVILIAPKGSGTSLRRMFLQG
                     RGLNSSYAVFQDATGRAFERVVALGIGVGSGYLFETDFKREVYSDLTGERGTLMGAIQG
                     IFAAQYDTLRANGHTPSEAFNETVEELTQSLMPLVSENGMDWMYANCSTTAQRGALDWW
                     KKFRDATKPVFEELYREVAAGNEAQRSIDLNSKPDYREKLNEELREMRESEMWQTGAVV
                     RKLRPENN"
     CDS             3635..3712
                     /locus_tag="ctg195_5"
                     /transl_table=11
                     /translation="MYSHDNRVVITLDAGGTNLVFGAMQA"
ORIGIN
        1 gcgtcgctgc gcgcctatgc ccggctggtc agctcggccg acaaaggcgc cgtacgtatc
       61 gtcgacgata acgaagaata aaaaacggac ccgcaatgaa tacctctcaa acactccgtc
      121 ccgaagagcg acgcgcggcc tccgacccct cgatgacggg atcgaaggcc ctgatcgaat
      181 catttctcca agagggcgtc gaaaccgttt tcggctatcc cggaggcgcg atcatccccg
      241 tctacgacgc gctttacgac taccgcgacc gcctgcgcca catcctcgta cgtcacgagc
      301 agggcgccgt gcacgccgca cagggctatg cccgcgtcag cggccgcgtc ggggtctgtc
      361 tggtgacctc gggtcccggc gccacgaaca ccgtgacggg gctggccgac gcgctgatgg
      421 actccacgcc gctggtgctc gtcaccggac aggtcggctc cgcgctgctg ggcaccgacg
      481 cctttcagga gaccaatttc atcggcatca cgcaggccgt caccaaatgg aactgccagg
      541 tcaagcgcac cgaggacatt cccgcggcca tcgccaaggc cttctacatc gcccgctcgg
      601 gccgtccggg tcccgtcgtg gtcgacatca ccaaggacgc acaatgcgga acagctccgt
      661 tccgctacga aaaaatcacc tcgatccgca gttacctccc cgcgcccgcc cccgacgcgg
      721 aacgcatcgc cgaagccgca cggctgatcg accaggcccg ccgtccgctg gtcatggtgg
      781 gtcagggcgt catcctgggc aacgccgaag ccgagctgcg ggcactgctc gacaagagcg
      841 gcatgcccgc cgcctcgacc ctgctgggtc tctcggccct gccgaccgac catccgcaaa
      901 acgtgggcat gctgggcatg cacggcaact acggacccaa catcaagaat caggagtgcg
      961 acctgctcgt ggccgtgggc atgcgtttcg acgaccgcgt gacggggaat cccgcgcatt
     1021 tcggcgccaa tgccaaggtg atccacctgg agatcgaccc cgcggagatc ggcaagatca
     1081 tcccggccga cgtggcggtc gtgggcgatg tgaaacgctc cctgccgctc atcaccgagn
     1141 nnnnnnnnnt caccgagcgt atccgcaaac gcaaccacag ccaatggatc gccggattcc
     1201 gcgcctgcga ccagatcgaa tacgaagccg tcatccgcaa ggccgtgcac cccgccgagg
     1261 ggcgtatccg catgggcgag gcggtcgccg ccgtggcccg ggcctaccgc aacgacgcgg
     1321 tgctggtgac cgacgtgggc cagcagcaga tgaacgccgc gcgctatttc ggattccgcc
     1381 gcacgcgcag cgtggtcacc tcgggcggtc tcggcacgat gggattcgga cttccggctg
     1441 ccatcggggc caagctgggc gcccccgacc gcgaagtcgt ccttttcgcc ggcgacggcg
     1501 gcctgcaaat gaccattcag gagctgggca cgatcttcca gtcgaagatc cccgtgaaaa
     1561 tcgtcctgct gaacaactcg ttcctcggca tggtgcgcca atggcaggag ctgttctacg
     1621 accgccgcta ctcctttacg gagatggtca accccgattt cgggctgatc gcccgcggca
     1681 acggcctttc gtaccgctgc gtcgaacggc gcgaggaact cgacgaggcc atcgccgcca
     1741 tgaaggcctc cgaaggcgcc ttcctgctcg aggtgcgcgt cgagggcgaa gagaacattt
     1801 tcccgatggt cccggcgggc gccccggtat cggaaatccg gttcgaataa aacgaaacag
     1861 cgtatggaac aggaatacat catcaccgtg ttttcggaga acaaggtggg cctgctgagc
     1921 cagatcacca ccgtcttcac ctgccgcgac gtgaacatcg agagcctcac aacctcggaa
     1981 tcggcgttgc agggcatcca caaattcacc atcgtggtcc gcaccacacc cgatcaggtc
     2041 gacaaactcg tgcggcaggt cgagaagaag atcgacgtgc tgaagacctt cgtctacacc
     2101 cccgacgagg tcgtgcagca ggagatcgcc ctctacaagg tgacccgcag ccggggcgtc
     2161 gaacaactcg tcagggaaca caacgtccgc attctggaga tcgacgagga ctacatcgtc
     2221 gtcgagaaga ccggccacaa ggccgacacg caggcgttgt tccgcctgct gcaaccctac
     2281 ggcgtacagc agttcgtgcg cagcggcacg gtggccatca tcaagtcgcg gcgcgagctg
     2341 ctgaacgagt accttgaaga aatcgaccgt ttaagggccg aatccgatga agaagggagc
     2401 aaaagcgaaa aataactttc agaacatata acaaactcaa aatcacgaaa atcatggcaa
     2461 agatcaattt cggcggcgtc gaagagaacg tcgtaacccg cgaggaattt cctctggaaa
     2521 aagcgctcga aacactcaag gacgagacca tcgccgtcat cggctacggc gtgcaaggcc
     2581 ccggacagtc gctcaacctg cgcgacaacg gattcagggt catcgtgggc cagcgcgaag
     2641 gctccgcgag ctgggacaag gccgtagccg acggctgggt gccgggccag acgcttttcg
     2701 gcatcgagga ggccgccgag cgcgccacga tcatccagta cctgctctcc gacgccgggc
     2761 agatcgccgt atggccttca atcaaaaagc acctcacgcc gggcaaggcc ctctatttct
     2821 cccacggctt cggcatcacc tacaaggagc gcacgggcat cgtgcccccg gccgatgtgg
     2881 acgtgatcct gatcgccccg aaaggctcgg gaacctcgct gcggcgcatg ttcctccagg
     2941 gccgcggact caattcgagc tatgcggtgt tccaggacgc cacgggccgc gccttcgaac
     3001 gcgtcgtggc gctgggcatc ggcgtgggtt cgggctacct gttcgaaacc gacttcaagc
     3061 gcgaggtcta ctccgacctc acgggcgagc gcggcacgct gatgggcgcc atccagggca
     3121 tcttcgccgc ccagtacgac acgctgcgcg ccaacggcca caccccctcg gaggccttca
     3181 acgaaacggt cgaggagctg acccagtcgc tcatgccgct ggtctcggag aacggcatgg
     3241 actggatgta cgccaactgt tcgaccacgg cccagcgcgg cgcgctggac tggtggaaga
     3301 agttccgcga cgccacgaag cccgtcttcg aagagctgta cagggaggtg gccgccggca
     3361 acgaggccca gcgttcgatc gacctgaaca gcaaacccga ctaccgcgag aagctcaacg
     3421 aggagctgcg cgagatgcgc gaaagcgaga tgtggcagac cggcgccgtc gtgcgcaagc
     3481 tgcgtcccga aaacaactga cacaaggcaa ggtcctgaaa aaggccggcg gcagcagtcg
     3541 ccggcctttt tcgcgcaatt cggttttgca cccgttcaat ttttatgtat ctttgcctgc
     3601 cggaacaccg gcaatccaaa caaaactact caatatgtac agccatgaca accgggtggt
     3661 catcaccctc gacgccggcg gcacgaacct cgttttcggc gccatgcagg cc
//
