LOCUS       c00055_gnlPro..        13092 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LOAAGADI_55.
ACCESSION   c00055_gnlPro..
VERSION     c00055_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:24:17
            Original ID  :: gnl|Prokka|LOAAGADI_55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4653
            Orig. end    :: 17745
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13092
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14653:17411]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12758
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13092
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13092
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(1098..2579)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_aromatic"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_8"
                     /sec_met_domain="Lyase_aromatic (E-value: 5.1e-190,
                     bitscore: 621.8, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHHHITAEHLSVGRVREILERRLPLALSDDARARIVRCREYLDR
                     KMENPERPIYGITTGFGSLCDISVGSDELSRLQQNLVMSHACGTGERVPSEIVRLILLL
                     KIQSLAYGHSGVQLATVERLVEFFNRGILPVVYQQGSLGASGDLAPLAHMSLPLLGLGE
                     VEYKGEVRPSAEVLAELGLEPIRLQSKEGLALLNGTQFMSAYGVWSLIHARRLSEWADR
                     IGALSLDAFDGRIEPFCDEVHLIRAHRGQLATARNVRGLLEGSELIVRPKHHVQDPYSF
                     RCMPQVHGASKDTIDYVESVLTTEINSTTDNPTVFPEEDMVVSAGNFHGQPIALAMDFL
                     AIALAELGNISERRTYKLISGARELPKFLVANPGLNSGFMIPQYTAASIVSQSKGLCMP
                     ASVDSIPSSQGQEDHVSMGSNAATKLWRVVCNTERVLAIELFNAAQAIEFRRPAHTSPE
                     LERMLADYRKEVPFIDNDEVMYPHIEASVRFLRGL"
     CDS             complement(2611..4650)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_9"
                     /sec_met_domain="Urocanase (E-value: 6.4e-91, bitscore:
                     293.5, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 4.6e-91, bitscore:
                     293.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 6.6e-61, bitscore:
                     193.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTREEFQNDIRAGIPDRLPAAKPYDKQINHAPKRKDILSDEEKTL
                     ALKNALRYFPVRHHAVLAKEFAEELRRYGRIYMYRLRPDYEMHARPIGEYPARCRQAAA
                     IMLMIQNNLDPRVAQHPHELITYGGNGAVFQNWAQYRLAMQYLSEMTENQTLVMYSGHP
                     LGLFPSHPDAPRVVVTNGMVIPNYSKPDDWERLNALGVSQYGQMTAGSYMYIGPQGIVH
                     GTTITVMNAARKRFTAGRTDTRGMLFVSSGLGGMSGAQPKAGNISGVVSVVAEINPKAA
                     QKRHEQGWVDELHEALDELIPRIRQAVKAKEVVSMAYVGNVVDLWERLAAEEIPVDLGS
                     DQTSLHNPWAGGYYPVGLSYEASNKMMAEEPGRFRECVQESLRRQVDAINKLTDRGMYF
                     FDYGNAFLLEASRAGAAVTGEGGRFRYPSYVQDIMGPMFFDYGFGPFRWVCTSGKPEDL
                     ETTDSLAAEVLEEIRKTAPDDIRGQLDDNIHWIREAGRNRLVVGSQARILYADCEGRVK
                     IAEAFNRAIAEGRITAPVVLGRDHHDVSGTDSPYRETSNIYDGSCLTADMAVQNVIGDA
                     FRGATWVSIHNGGGVGWGEVINGGFGMVIDGSEDAGRRIREMLLWDVNNGIARRSWARN
                     EGAVEAIRREMDRTPGLRVTLPVFADEELVREALNEQGGASDKL"
     CDS             complement(4652..6352)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTCD_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_10"
                     /sec_met_domain="FTCD_C (E-value: 7e-67, bitscore: 214.6,
                     seeds: 242, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQRIIECVPNFSEGRDKAVIRQITAAIEASGGVKLLDVDPGEAT
                     NRTVVTFVGEPEAVVEAAFAGVKRAAELIDMRRHKGAHPRMGATDVLPLIPIAGVTLAE
                     CAELARALARRIADELRIPTYCYEAAAFAPERKNLAVCRAGEYEALPEKLAHTASAPDF
                     GARPFDEGVARTGATTVGARDFLIAVNFNLNTTSTRRANAIAFDVREKGRPVREGNPIT
                     GRVVKDAAGNPVMQPGTLPATKAIGWFIEEYGIAQVSMNITDISRTPLHAAFDEVCRKA
                     DARGVRVTGTEIVGLVPKRALVEAGKYFLRKQRRSTGVAEEEIVRIAVKSMGLDDLKPF
                     DPAEKVIEYLLEAEVPKKRLIDMTCKAFAEETASESPAPGGGSIAAYMGALGAALGTMV
                     ANLSSHKAGWDDRWEEFSDWAERGQAVLAELLHLVDEDTAAFNRIMAVFAMPKSTDEEK
                     AARSAALQEATLYATEVPLRTMKAASRVFEIVRAMASEGNPNSVSDAGVGALAARSAVL
                     GACLNVKINAAGLKDRAVADALIAEADALAAEAVRLEAEVLQIVESKIG"
     CDS             complement(6541..8523)
                     /locus_tag="ctg55_11"
                     /transl_table=11
                     /translation="MENIQTKQYPCFKRWSRKNWSIFASLHRYVTIGVLSVGMSILLLA
                     TQGASAQTADTTAVLKTLRIREVGVTGSQTAPARNAQSHTPLFDRKAQAPAPVQTLEAA
                     LRLAPSVDVRERGGKGTQADIFIRGGSFDQTMVLLNGIDFTDARTGHQSHALPVDLDCI
                     SAVELIDGVPGVGAYAGAVNIRTAPLRSTYLRLEASGGQYSYGYGNLSGAVSAGRFSVL
                     GAASYRRSDGYRHNTDFSNYNAFVRATYDGGRAGFFDLQAGWQDRDFGSNGFYAAYNPD
                     QWEHTATALGSLRWLKTAGRFSLGAAASYRKNFDRYDWTRGTAMNRHNTDNVGAKLWAD
                     CDWAAGVTTVGGDYAFNHIYSTNLGDKLSVPEGHYTHAKARHTGNLWLRHAKRWRHFDA
                     AASAGVSLTPYGTSALWSLSAGYAPAAGLRLEAGAWQSMRLPTFTDLYYTSPAQINNLD
                     LTPEHAVTYRLGVDYLKRSWNLSAQAYYRSGRDIIDWVWREDMGSKWHSEQTSSLDTFG
                     IELAGGYTVSEGFLRRVTLSYGYITTDRNADVIAKSAMDFMRHKAALAVEVHFLRRMSL
                     ALTGSVYDRNGSYTHYPEPGNASLNEERDYKPYFLLDGRLQWEKGICRLYVDATNITDT
                     RYCDIGGIRLPGFWCTGGVTLTIGK"
     CDS             complement(8675..9967)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg55_12"
                     /sec_met_domain="PALP (E-value: 2e-28, bitscore: 89.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFTPTPYTLECVATGREFEDAGWMLADPQCKEPSLVRTKYARK
                     QIDVKPADWGLYRFSDWMPVRRILKGSSAPVTYKSKGLAAHLGLENLWITFNGWYPAIG
                     ATMSTCSFKETEAYSVCGRAAADERRVLVVASAGNTARAFAKVCSDNNIRLLLSVPYDN
                     IGALWFDQPLNPCVKLISCEKGGDYFDAIHLSDIALKSPGFYAEGGAKNVARRDGMACT
                     VLSAVTTIGRIPDYYFQAVGSGTGAIAAWEANMRLVEDGRFGRNTMKLMVAQNAPFVPM
                     YDAWQAASRKLLPYDDDKARRDAEIIDAKVLSNRRPPYSVTGGLFDALKATGGEVFVAT
                     NAMARKARKLFHELEGVDIYSAAGVALASLVNAVNAGKIEKDATVMLNVTGGGEEHFKE
                     GKELWYLKPSHVFPLEPDEADVVEKVEALFN"
     CDS             complement(10001..11140)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_13"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.2e-11,
                     bitscore: 34.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDFLKLPSPCYVLDEELLDRNLATVDRVRRESGAEIIVALKACA
                     MWSIFPELAKHSDGATASSAAEARLVFEEFGRPAHTYAPVYTDSNIDEILNCSDHITFN
                     SLSQFRRFGQKALINGISCGLRINPQYSPVETDLYNPCVPGSRLGVTAEQLAAHGGLPA
                     GVEGLHFHVLCESRPEHLQKALEAVETHFGAYLDRIKWLNMGGGHLMTASWYDCDRLIA
                     LLKAFRSRHPNLRLILEPGSAFTWRTGFLVSTVEDIVENGGVTTAMLDVSFACHMPDCL
                     EMPYKPAVIGAHEPADGEKRWRMGGTSCLAGDYCGDWAFDRELKVGERVVFEDMIHYTM
                     VKTTMFNGVHHPAIVIARRDGRTDVIREFGYEDFRNRMS"
     CDS             complement(11568..12758)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_14"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.4e-39, bitscore:
                     126.6, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3.6e-36,
                     bitscore: 114.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKALIIGAGGVGTVVTQKIAANPVFTDVMLASRTKSKCDAVAAA
                     IGGNRVKTAEVDADSVPQLCELFRAFKPDIVVNVALPYQDLTIMDACLECGCNYLDTAN
                     YEPKDEAHFEYSWQWAYQDRFKAAGLTAILGCGFDPGVTAIFTAYAAKHHFDEIHYLDI
                     VDCNAGNHGMAFATNFNPEINIREVTQKGRYYENGEWVVTEPHEIHKPLNYPGIGERES
                     YVIYHEELESLVKNYPTIRRARFWMTFGQEYLTHLRVIQNIGMARIDPIIYNGVEIVPI
                     QFLKAVLPDPKSLGANYHGQTSIGCRIKGLKDGKERTYYIYNNCDHEQAFKETGTQAVS
                     FTTGVPAALGASMWAKGLWRGAGVFNVEEFDPDPFLAELGEQGLPWHELFDVNLEV"
ORIGIN
        1 gcggctcaac cccatggcat aggcgccgtt gagcgtcgcg gcgttgatcg cctcggcggg
       61 ggtcatcttc atgcggatcg aggccagcga acagaccatg cgcatgttgc ccgagggcga
      121 cgacccgggg ttgtagtccg aagccagcgc cacgcccagc ccggcgtcga tcatcgcgcg
      181 cgccggagga tagctcatcc cgaggaagaa cgccgcgccc ggcagcagcg tcggcatggt
      241 cgccgcgccg cgcagcgcct cgatctcctc ccgtcccatg cgttcgaggt ggtccaccga
      301 cagggcgtcg caggccacgc ccacctgcac gccgcccgag acggccagtt cgttggcatg
      361 gattttcgcc cgcagcccca gtttgcgcgc agccttgagg atacgggccg tctcttcgac
      421 cgtgaaaaaa ccttcgtcgc agaagacgtc gacgaaatcg gccagccctt cggccgccac
      481 ggcgggcagc atttcgttgc acaccagatc gacatactcc ccctgccgtc cccggtaggc
      541 acgcgccacg gcatgcgccc cgaggaatgt ggcccgcacc tccagcggca cactttcgcg
      601 gatgcggcgg atgacgcgca gcatcttcag ctcgtccccg gtcgaaaggc cgtagccgct
      661 cttgatctcc acgcaccccg tacccatcgc cgcgatctcg cgcacgcgct ccatcgcctg
      721 cgcatagagt tcgtcctccg gagtctcgtg cagccggtcg gcggagttga gaatgccccc
      781 gccccgccgg gcgatctcct cgtacgacaa accgttgatc ttgtccagaa actcccgctc
      841 gcggctcccg gcgtagacca ggtgggtgtg cgagtcgcag aacgacggga agagcatgcc
      901 ccctgccgcg tcgacgacct cgtcggcggc gatgtcgccc agagagtcca tgcgtccgaa
      961 cgccgcgaaa cggccgtctt cagccagcag ccacgcgtcg tcgagcgtgc ccagcttgtt
     1021 catgtcggcg ccgcagcagc gcagacggcc cgtcgattcg atgccgacga tgcgggcgat
     1081 gttcttcacc agcagtctca taggccgcgg aggaatcgga cggaggcttc gatatgggga
     1141 tacatcacct cgtcgttgtc gatgaaggga acctctttgc gatagtcggc cagcattcgc
     1201 tccaactcgg gcgacgtatg cgccgggcgg cggaactcga tggcctgcgc ggcgttgaac
     1261 agctcgatgg ccagcacccg ttcggtgttg cagaccacgc gccagagctt cgtggcagcg
     1321 ttggaaccca tgctcacatg gtcctcctgc ccctgcgacg aggggatcga atcgaccgac
     1381 gcgggcatgc acagcccctt ggactggctc acgatcgacg ccgcggtata ctgcggaatc
     1441 ataaagccgc tgttcagccc ggggttcgcc acgaggaatt tgggcagttc gcgcgccccg
     1501 gagatcagtt tgtaggtgcg acgctcggag atgttgccca gctcggccag ggcgatcgcc
     1561 aggaaatcca tcgccagagc gatcggctgt ccgtggaaat tgcccgccga gacgaccatg
     1621 tcctcctcgg ggaagaccgt cggattgtcc gtcgtggagt tgatttccgt ggtcagcacg
     1681 ctctccacat agtcgatcgt gtccttcgag gctccgtgaa cctgcggcat gcagcggaac
     1741 gaataggggt cctgcacgtg gtgcttgggg cggacgatca gttcgctgcc ttcgagcagc
     1801 ccgcggacat tccgggccgt ggcgagctgc ccccggtggg cgcggatcag gtgcacctcg
     1861 tcgcagaaag gctcgatacg accgtcgaag gcgtctaacg acaacgcccc gatgcggtcg
     1921 gcccactcgc tcagccgccg ggcgtggatc agcgaccaga cgccgtaggc gctcataaac
     1981 tgcgtgccgt tcagcagcgc aaggccctct ttcgactgca accggatcgg ctccagcccc
     2041 agttcggcaa gcacttcggc cgaaggacgc acctcgccct tatactccac ctcgcccaac
     2101 cccagcagcg gcaggctcat atgtgccagc ggcgcgaggt cgcccgaagc gcccagcgaa
     2161 ccctgctgat agacgacggg caggatgccg cggttgaaaa actccacgag acgctccacc
     2221 gtcgccagct gcacgcccga atggccgtag gcgagcgact gtatcttgag cagcagaatc
     2281 agccgcacga tctccgaggg cacgcgctcc ccggttccgc aggcgtgcga catcacgagg
     2341 ttctgttgca ggcgcgacag ctcgtcgctg cccaccgaaa tatcgcacag cgacccgaaa
     2401 ccggtcgtga tgccgtagat cggccgctcg gggttctcca tcttgcggtc gaggtactcg
     2461 cggcagcgga cgatgcgcgc ccgggcgtcg tcgctcaacg cgagcggcag ccgccgttcg
     2521 aggatttcgc ggacgcgccc gaccgaaagg tgctccgcgg tgatatggtg atgttccatg
     2581 gatgacaatt caaaattcat aattcgaaat tcataattta tccgaagcgc cgccctgttc
     2641 gttcagcgcc tcgcggacaa gttcctcgtc ggcaaaaaca ggcagggtca cacgcagtcc
     2701 gggcgtgcgg tccatttcgc ggcggatggc ttcgacggcc ccttcgttac gcgcccagct
     2761 gcggcgcgcg atgccgttgt tgacgtccca cagcagcatt tcgcggatgc ggcggccggc
     2821 atcctccgaa ccgtcgatca ccatgccgaa gccgccgttg atcacctcgc cccagcccac
     2881 gccgcctccg ttgtggatcg aaacccacgt cgcgccgcgg aacgcatcgc cgatgacgtt
     2941 ctgcacggcc atgtcggccg tcaggcacga accgtcgtag atgttcgagg tctcgcggta
     3001 gggcgaatcg gttcccgaaa cgtcgtgatg gtcgcgcccc agcaccacgg gagccgtgat
     3061 gcggccctcg gcgatggccc ggttgaacgc ctcggcgatc ttcacgcgcc cttcgcagtc
     3121 ggcatagaga atgcgcgcct gcgacccgac gaccagccgg ttgcgcccgg cctcgcgaat
     3181 ccagtggata ttgtcgtcca gctgcccccg gatgtcgtcg ggagccgtct tccggatctc
     3241 ctccagcact tcggcggcca gagagtcggt cgtttcgagg tcttcgggct tccccgaggt
     3301 gcagacccag cggaacggcc cgaagccgta gtcgaagaac atgggtccca taatgtcctg
     3361 cacgtaggag ggatagcgga agcgtccgcc ctcgcccgtc accgcggccc cggcgcgcga
     3421 ggcttccagc aggaaggcat tgccgtagtc gaagaaatac attcccctgt cggtcaattt
     3481 gttgatggca tcgacctgcc gccgcagcga ctcctgcaca cactctctaa agcggcccgg
     3541 ctcctcggcc atcatcttgt tcgacgcctc gtagctcaac cccacgggat agtaaccgcc
     3601 cgcccagggg ttgtgcagcg aggtctggtc cgaacccagg tcgaccggaa tctcctccgc
     3661 ggccagccgc tcccagaggt ccacgacgtt gcccacatag gccatcgaca cgacctcttt
     3721 cgccttgaca gcctggcgga tacgcgggat cagctcatcc agcgcttcat gcagctcgtc
     3781 gacccatccc tgctcgtggc gtttctgcgc cgccttgggg ttgatctcgg cgacgaccga
     3841 caccacgccc gaaatattgc ccgccttggg ctgcgctccc gacatgccgc cgagacccga
     3901 cgagacgaac agcatcccgc gcgtatcggt gcggccggcc gtgaagcgtt tgcgcgcggc
     3961 gttcatcacc gtgatcgtcg tgccgtggac gatgccctgc ggcccgatat acatgtacga
     4021 cccggcggtc atctgcccgt actgcgacac cccgagggcg ttgagccgct cccagtcgtc
     4081 gggtttcgag tagttgggaa tcaccatgcc gttcgtaacc accacgcgcg gggcgtcggg
     4141 atgcgacggg aacagcccca gcggatgccc ggaatacatg accaaggttt gattttcagt
     4201 catttccgaa agatactgca tcgcaaggcg gtactgcgcc cagttctgga acacggcgcc
     4261 gttgccgccg taggtgatca gctcgtgggg atgctgggcg acccgcgggt cgaggttgtt
     4321 ctgaatcatc agcatgatgg ccgccgcctg ccggcagcgg gcgggatatt cgccgatcgg
     4381 acgcgcgtgc atctcgtagt cgggacgcag gcggtacata tagatacggc cgtagcggcg
     4441 cagctcctcg gcgaactcct tcgccagcac ggcgtggtgc ctgaccggaa aatagcgcag
     4501 ggcgtttttc agagccagcg tcttctcctc gtccgaaagg atgtccttgc gtttgggcgc
     4561 atggttgatc tgtttgtcat agggtttcgc ggcgggcagc cggtcgggaa tgcccgcgcg
     4621 aatgtcgttc tgaaactctt cgcgtgtcat attatccgat tttagattcg acgatctgca
     4681 agacctccgc ttcgagacgc acggcttcgg cggccagcgc atcggcttcg gcgatcagcg
     4741 catcggccac ggcacggtcc ttcagccccg cggcgttgat cttcacattg aggcacgccc
     4801 ccagcaccgc gctgcgggcc gccagcgcac ccacgccggc gtcggagacc gaattggggt
     4861 tgccctccga ggccatggcg cgcacgattt caaaaacccg cgaggcggcc ttcatcgtcc
     4921 gcagaggaac ctccgtggca tagagcgtcg cctcctgcaa cgcggcgctg cgcgccgcct
     4981 tctcctcgtc ggtcgacttg ggcatggcga aaaccgccat gatgcggttg aacgccgccg
     5041 tgtcctcgtc cacgaggtgc agaagctccg caagaacggc ctgcccccgt tcggcccagt
     5101 cggaaaactc ctcccagcgg tcgtcccacc ccgccttgtg cgacgagagg ttggcgacca
     5161 tcgtcccgag ggccgcgccc agcgcaccca tgtaggccgc gatcgagccg ccgcccggag
     5221 cgggagattc gctcgccgtc tcttcggcga acgccttgca ggtcatgtcg ataagccgct
     5281 tcttcggaac ctccgcttca agcaggtact cgatcacctt ctcggcagga tcgaacggct
     5341 tcaggtcgtc caatcccatc gacttgacgg caatgcggac gatctcctcc tcggcgacgc
     5401 ccgtcgagcg acgctgcttg cggaggaagt atttgccggc ttcgaccaaa gcccgtttcg
     5461 gaaccagccc cacgatttcg gtccccgtga cgcgcacgcc gcgggcgtcg gccttgcggc
     5521 acacctcgtc gaaagccgcg tggagcggcg tccgggagat gtcggtgatg ttcatcgaaa
     5581 cctgcgcgat gccgtactcc tcgatgaacc agccgatggc cttcgtggcc ggaagcgttc
     5641 cgggctgcat cacgggattt cccgcggcat ccttcaccac cctgcccgtg atgggattgc
     5701 cctcgcggac gggacgcccc ttttcgcgca cgtcgaaggc gatggcgttg gcgcggcgcg
     5761 tggaggtggt gttcaggttg aaattcacgg cgatcaggaa gtcgcgcgcc ccgacggtcg
     5821 tagctcccgt gcgggcgacc ccctcgtcga agggacgcgc cccgaaatcg ggcgcggatg
     5881 ccgtgtgcgc cagtttctcg ggcagggcct cgtactcccc ggcgcggcac acggcgaggt
     5941 ttttccgttc gggcgcaaag gccgcagcct cgtagcaata ggtcgggatg cgcagttcgt
     6001 cggcgatacg ccgggccagc gcacgcgcca gttcggcgca ctccgcaagc gtgacgcccg
     6061 caatcggtat cagcggcagc acgtcggtgg cccccatgcg gggatgcgcc cccttgtggc
     6121 ggcgcatgtc gatcagttcg gccgcccgct tcactccggc aaaagcggcc tcgacgaccg
     6181 cttcgggttc gccgacgaag gtcacgaccg tgcggttggt cgcctcgccg gggtccacgt
     6241 cgagcagttt gacgcccccg gaggcctcga tggccgcggt gatttgccgg atcacggcct
     6301 tatcgcgtcc ctcgctgaaa ttgggaacgc attcaatgat tctttgggac ataggatcgt
     6361 cgcatttaaa ttcttatact tcaaagataa ataataatcg ggagaaatcc gaaaaaaccg
     6421 taacaaaaca ggcggctttt tgcgaaaaac agaaaggccc ggtgcacaaa tgcaccgggc
     6481 caggattgca gccggaccga aatccggggg cggaagcgcc ccggtcccgg aaaagagagg
     6541 ttatttgccg atggtcagcg tcaccccgcc cgtacaccag aaacccggca ggcggattcc
     6601 gccgatgtcg cagtagcgcg tgtcggtgat gttcgtggcg tcgacataaa ggcggcagat
     6661 gcccttctcc cactggagac gtccgtcgag caggaaatag ggcttgtagt cgcgttcttc
     6721 gttaagggag gcgttgcccg gttcggggta atgcgtatag ctgccgttgc ggtcgtagac
     6781 cgagccggtc agcgcaagcg acatccgccg caggaaatgc acctccacgg ccaatgccgc
     6841 cttgtgacgc atgaaatcca tcgcgctttt ggcgatgacg tccgcgttcc ggtcggtcgt
     6901 gatgtagccg tacgagagcg tcacgcggcg caggaagcct tccgaaaccg tatagccgcc
     6961 cgcgagttcg atcccgaagg tatcgaggct gctcgtctgt tcggaatgcc acttgctgcc
     7021 catgtcctcg cgccagaccc agtcgatgat gtcgcgcccg gagcggtaat aggcttgcgc
     7081 cgaaaggttc cagctccgct tgaggtaatc cacaccaagt cggtatgtga ctgcgtgttc
     7141 cggcgtaaga tcgagattgt tgatctgcgc cggggaggtg tagtagaggt ccgtgaaggt
     7201 cggcaggcgc atcgactgcc acgccccggc ttcgaggcgc agcccggccg cgggggcata
     7261 gcccgccgaa aggctccaca gggccgaagt gccgtagggc gtgaggctca cgcccgccga
     7321 agccgccgcg tcgaaatgcc gccaccgctt ggcgtgccgc agccacaggt tgcccgtgtg
     7381 gcgcgccttg gcatgggtgt aatggccttc gggaaccgaa agcttgtcac ccagattggt
     7441 gctgtaaatg tggttgaaag catagtctcc gcccacggtg gtaacgcccg ccgcccagtc
     7501 gcagtcggcc cagagcttcg ctccgacatt gtccgtgttg tggcggttca tcgccgtgcc
     7561 gcgcgtccag tcgtagcggt cgaagttctt gcggtagctc gcggcggccc ccagcgaaaa
     7621 gcggcctgcg gttttcagcc accgcagcga ccccagggcc gtggcggtat gctcccactg
     7681 gtcgggattg taggccgcat agaaaccgtt ggagccgaaa tcgcggtcct gccacccggc
     7741 ctgcaagtcg aagaacccgg cccgcccgcc gtcgtaggtc gcccgtacga atgcgttgta
     7801 gttggagaaa tcggtattgt gccggtagcc gtcgctgcgg cggtacgaag ccgcgccgag
     7861 caccgagaag cgtcccgcac tcaccgcgcc cgaaagattc ccgtagccat agctgtactg
     7921 gccgcccgag gcttcgagac gcaggtaggt ggaccgcagc ggcgcggtgc ggatgttcac
     7981 cgcaccggcg taggctccga cgcccggaac gccgtcgatc agttcgacgg ccgaaatgca
     8041 gtcgaggtcg acgggcagcg cgtgtgactg atgcccggtg cgggcatcgg tgaaatcaat
     8101 gccgttgaga aggaccatgg tctggtcgaa agagcctccc cggatgaaga tgtcggcctg
     8161 cgttcccttg cctccgcgtt cgcggacatc gaccgaagga gcaaggcgca gggcggcttc
     8221 cagagtctgg acaggcgccg gggcctgggc tttccggtcg aaaagcgggg tgtgcgactg
     8281 ggcgttgcgc gcgggagccg tctgactccc ggtgacgccg acttcccgta tccgcaatgt
     8341 cttgaggaca gcggtcgtgt cggcagtctg cgcagacgca ccttgcgtcg caagcagcag
     8401 gatcgacatc ccgacagaga ggaccccgat agtcacataa cggtggagac tggcaaaaat
     8461 cgaccagttt ttgcgactcc aacgcttgaa gcaggggtac tgctttgttt ggatgttttc
     8521 catttgtttg aaatttggat taaaagtgaa aaaacgtccc aaccgggtcc ggctgctgat
     8581 ccccggttcg gacgcgcaaa ggtaacaaaa aaaacgggct atacaggccc gtttgtgtaa
     8641 atcgcacaga agcaatcagt caacccgctg tcattcagtt gaacagcgct tcgactttct
     8701 ccaccacatc cgcctcgtcg ggttcgagcg ggaagacgtg gctcggcttg agataccaca
     8761 gctccttacc ctccttgaag tgctcctcgc cgccgcccgt gacattgagc atgacggtgg
     8821 cgtccttctc gattttaccc gcgttcacgg cattgacgag cgacgccagc gcaacgcccg
     8881 ccgccgaata gatgtcgacg ccttcgagtt cgtggaacag cttgcgggcc ttgcgcgcca
     8941 tggcgttcgt ggccacgaaa acctcgccgc cggtggcttt cagcgcatcg aaaagaccgc
     9001 ccgtgacgct gtaaggcgga cggcggttcg aaagcacctt ggcgtcgatg atctccgcgt
     9061 cgcggcgcgc cttgtcgtcg tcgtaaggca gcagcttgcg cgatgccgcc tgccaggcgt
     9121 cgtacatcgg gacgaacggg gcgttctgcg ccaccatcag tttcatcgta ttccgcccga
     9181 agcggccgtc ctccaccaga cgcatgttag cctcccaagc ggcaatggcg cccgtgccgc
     9241 tgcccacagc ctggaaatag tagtcgggaa tgcggccgat ggtcgtcacg gccgaaagga
     9301 ccgtgcaggc catgccgtcg cgacgcgcga cgttcttggc gccgccctcg gcgtagaagc
     9361 cggggctttt cagcgcgatg tcgctcaaat ggatggcgtc gaaatagtcg ccgcccttct
     9421 cgcacgaaat gagtttcacg caggggttca gcggctggtc gaaccacagc gcgccgatat
     9481 tgtcgtaggg aaccgagagc agcagcctga tgttattgtc cgagcagacc ttggcgaagg
     9541 cccgggcggt gtttccggcc gaagccacca ccagcacgcg ccgttcgtcg gcagcggcgc
     9601 ggccgcagac cgaataggcc tcggtctcct tgaacgagca ggtcgacatc gtggccccga
     9661 tggccggata ccagccgttg aaggtgatcc agaggttttc cagcccgagg tgcgcggcga
     9721 ggcccttgct cttataggtc acgggagccg acgaaccttt gaggatacgc cgcacgggca
     9781 tccagtccga gaaacggtac aggccccagt cggcgggctt cacgtcgatc tgtttgcggg
     9841 cgtatttggt gcgcacgagc gaaggctcct tgcactgcgg gtcggcaagc atccagccgg
     9901 cgtcttcgaa ttcgcggccc gtggcgacac attccaacgt gtagggggta ggtgtgaaat
     9961 tttccatgaa gaggtttcgt atatctgaat tcaatattgt ctatgacatg cggttccgga
    10021 agtcctcgta gccgaattcg cggatgacgt cggtgcggcc gtcgcggcgc gcgatgacga
    10081 tggccggatg gtggacgccg ttgaacatcg tggtcttgac catcgtgtag tggatcatgt
    10141 cctcgaagac gacgcgctcc cccaccttca gctcgcggtc gaaagcccag tcgccgcagt
    10201 agtcgcccgc aaggcagctc gtgccgccca tgcgccagcg cttttcgccg tcggcaggtt
    10261 catgcgctcc gatgacggcg ggtttgtagg gcatttcgag gcagtcgggc atgtggcagg
    10321 cgaacgacac gtcaagcatc gccgtcgtca ccccgccgtt ctccacgatg tcctcgacgg
    10381 tcgaaaccag aaagcccgtg cgccacgtga aggcactgcc gggttcgagg atcagccgca
    10441 ggttcggatg gcgggacctg aacgccttca gcagggcgat caggcggtcg cagtcatacc
    10501 acgaggccgt catcaggtgg ccgccgccca tgttgagcca tttgatccgg tcgagatacg
    10561 ctccgaaatg cgtctcgacg gcctccagcg ccttttgcag atgctccggg cgcgattcgc
    10621 agaggacgtg gaaatgcagc ccctcgacac ccgccggaag tccgccgtgc gccgccagct
    10681 gttcggccgt gacgcccagc cgcgagccgg ggacgcaggg gttgtagagg tccgtctcga
    10741 cgggcgaata ctgcgggttg atccgcaggc cgcaggaaat gccgttgatc agggctttct
    10801 ggccgaagcg gcggaactgc gacagcgaat tgaacgtgat atgatcgctg caattgagga
    10861 tttcgtcgat attggagtcc gtgtagaccg gggcgtaggt gtgggcggga cgcccgaact
    10921 cctcgaaaac gagacgcgcc tcggcggcgg aacttgcagt cgcaccgtcg gaatgcttcg
    10981 ccagctcggg aaaaatgctc cacatggcgc aggccttcag ggcgacgata atttcggcgc
    11041 ccgattcccg gcgcacacgg tcgacagtcg ccaggttccg gtccagcagc tcctcgtcga
    11101 ggacgtagca cggtgaaggc agtttcagaa agtcaatcat cgaattgttt ttagttggat
    11161 ttcatccttc gttttctccg ctcggcataa tccgggcaaa cccggctctg ccctcgctca
    11221 acgaaaacgt ccaaaacagt tgcaaaagta gcaaaaacct cctgaaaacc acgctgcgca
    11281 ggcttggttt tcgggaaaat acgcatttat acttatcgct tgcgaaaccc ggtccggaaa
    11341 taagcatcgg agccggtcgc cggcaggggc atttcgggaa aagcggttct gcggaaaacg
    11401 atacgacagt tttgattttg gaggagcgga aaatcccgct gcggttttcg atcggtacgg
    11461 tgcatctgtc gtgcatcgtg aaaaatcccc ggatgggacg tacttcggca ctatccatcc
    11521 ggggattttg agggatgtgc ggcatctgcg ccgcaatctt caaaaaccta cacttcgaga
    11581 ttcacatcga acagctcgtg ccacggcagg ccctgctcgc ccagctcggc gaggaacgga
    11641 tcgggatcga actcctcgac gttgaacaca ccggcgccgc gccacagccc cttggcccac
    11701 atcgaagcgc ccaaagccgc cggaacgccc gtggtgaacg acacggcctg cgtgccggtc
    11761 tccttgaagg cttgttcgtg gtcgcagttg ttataaatat agtaggtgcg ctccttgccg
    11821 tccttcaggc ccttgatgcg gcagccgatc gaggtctggc cgtgatagtt ggcgcccagc
    11881 gacttgggat cgggaagaac cgccttaagg aactggatcg ggacgatctc gaccccgttg
    11941 tagatgatcg ggtcgatacg cgccatgccg atgttctgga tcacgcgcag gtgcgtcagg
    12001 tactcctgac cgaaggtcat ccagaagcgc gcacgccgga tcgtgggata gttcttcacg
    12061 agcgactcca actcctcgtg gtagatgacg tacgactcgc gctcgccgat gcccggataa
    12121 ttgagcggct tgtggatctc gtgcggctcg gtcaccaccc actctccgtt ctcgtaataa
    12181 cgccctttct gggtcacctc gcggatgttg atctcggggt tgaagttcgt ggcgaaagcc
    12241 atgccgtggt tgccggcgtt gcagtcgacg atgtcgaggt agtggatttc gtcgaaatgg
    12301 tgcttggcgg cataggccgt gaagatggcc gtcacgcccg ggtcgaaacc gcagccgagg
    12361 atcgccgtga gtcccgcggc cttgaagcgg tcctgatagg cccactgcca cgagtattcg
    12421 aaatgcgcct cgtccttcgg ctcgtagttg gccgtgtcga ggtagttgca gccgcattcg
    12481 aggcaggcgt ccatgatcgt gagatcctgg tacggaagcg ccacgttgac cacgatgtcg
    12541 ggtttgaacg cgcggaacag ttcgcacagc tgcggcacgc tgtcggcgtc gacctcggcg
    12601 gtcttcacgc ggttgccgcc gatggcggcc gcaacggcgt cgcatttgga tttggtacgg
    12661 ctggccagca tcacgtccgt gaagacggga ttggccgcga ttttctgcgt caccaccgtt
    12721 ccgacgccgc cggctccgat tatcagcgct ttacacatag aattattcgg ttttaaaagt
    12781 tagatttcat cttaacgcct acaaaaatat ccttttattt cggcaaaaca aaatccgcgc
    12841 gccaaatttc acgatcccgg ccggccgaaa ccgccggaag atgcccggac gcctatcgcc
    12901 tgcaggcggc agccggcagc cggaaaggca aaaaacacac ttttgcgcaa aatttgcagg
    12961 ccgggtattg gattttaaaa ataaatccgt acatttgcac caccaaaacg gaaacgattc
    13021 ccattttggc acacggagat tccgtagctc agctggtaga gcacaacact tttaatgttg
    13081 gggtcctggg tt
//
