LOCUS       c00022_gnlPro..        16520 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOFNDJFJ_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:11:56
            Original ID  :: gnl|Prokka|KOFNDJFJ_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 18687
            Orig. end    :: 35207
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16520
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[28687:33079]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14392
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..16520
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16520
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(66..956)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_19"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 3.7e-26, bitscore:
                     83.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDSITFGTGLKPGETRYPQVLATLMGPDFDVRGFGNPGKTAGDY
                     PGQAGRWYGSTREHKQALEFKADIYICNLGINDTGRWWNPELFSKGYDALLHAWKNANP
                     KTRFFAWGLLGPDYRGPLNKKAFPGNCYPDVRKYAGSDNGSSANRPEAEKLIAAVARKY
                     KVSLFDALHPLSDHPEWYVDGLHPTEQGARRIAEITFAKLAKSLRLKQPAPRLEPGTGN
                     VIINNPGNSGILLDGWKLTDGTNTLIFENSTVIHPKDRLIIAIGPETQKDPTKPLQIKS
                     AQSPAAFRLIPAKKY"
     CDS             complement(1065..2633)
                     /locus_tag="ctg22_20"
                     /transl_table=11
                     /translation="MNSFSNNPQTMRLHTSCILAAAIALHAAWADTPRFDRVFGSHMVL
                     PHGKNIPVSGTAAPNREITVTFGNTALKTKTDSKGKWSVTLPPMPPCATGQTLAAVQNG
                     DSAKLEDVLVGEVWLASGQSNMLFRLNQTTTAKEDIAASGDDQLRLLNNVPQAHTNNAP
                     YSAKDFDAVTTDNFYKGQWAASSPATSGPMTAVGYYFGKKLREGLGIPVGIIHSSLGGS
                     EIAAWIPRQVINANNSFRTLRGNHWLDSPLISDWVRGRARKNISPRLNQGSPDHPYKPA
                     FLYESGIAWTTALPITGVIWYQGESDAEIIDNAQNSMLLKTMISSWRKAFRNPEMPFVM
                     IQLPRINDPSKIRAGWPEFREMQDAVAKTVPKVYSVNTIDLGSTNSDVHPPFKRPVGER
                     AGNTALNKVYGKKIPCEGPALKAFKPSGSNILVQLDQAAGLTTTDGKEPAQFEIAGTDG
                     TYHPAAAEIINRKGNTAVIRLSSPEVKSPKHARYCWNRFVTPNLVNGNQLPARPFRTDE
                     PVLKK"
     CDS             complement(2614..3417)
                     /locus_tag="ctg22_21"
                     /transl_table=11
                     /translation="MVQIFPSEFMDKTPNKSQSSLLGIFINILLPVLILDYCSAGPANP
                     LERPEGESFWHIGPVWSLVIALSLPLVYGIRSLAVSRKFDLMSGVGMAGVLLTGVISIF
                     VIGPEGRIHSATPWLFAGKEALIPLILGAAVVVSRSAGTPLLNMFIYTPELFDVRRIEQ
                     TVAANGEERAYQKLLANSSWILAGTLVASSIGNFFLSLSFMSSVIQQPEAEQQVAYNAA
                     IGSITWWGFLIIGIPILAALVFIMTRLIKRLGRLTGLSRDELLLK"
     CDS             3906..5423
                     /locus_tag="ctg22_22"
                     /transl_table=11
                     /translation="MDGVSAVPIYGGASFRPQLDALRRGVQFVVGTPGRVMDLMESGAL
                     RLDGLRMLILDEADEMLDMGFLEDIERIAEAMPETKQTLFFSATMSPEINRLVSRFMKE
                     PIQISIERPTLTVPTIEQVYYEVVFSSRIEVLSRLLDTGKIKMGLVFANTKKVVDDVVD
                     GLTARGYPVDRLHGDMPQMMRERVMDSFRKGSLRLLVATDIAARGLDVDDVDAVVNFEL
                     PRDPEDYVHRIGRTARAGRKGKAITFVGRRDFSLMSRIERFIGVKLTPEPVLTAVQVDQ
                     LRTESLVDDILERLKPDAVLPEELKEVEAAPEAMAAALFDLLRERTHREVQPIPEDKPA
                     RRARRMPQTGEEAESPQKGDSWQHKGDTVTLFMNGGRMIGLRPKDIAGLFYNTVEMEKG
                     AVGDIRIFPKHSLIEVDASVAPLLLEALATATVCGYEVNVREDKGAPEYSGTPRSSRRN
                     GGFRNSYRGERDRSDRSGFRGNRGGFRSDRGERWGERSRRDDRKKRF"
     CDS             complement(5642..5794)
                     /locus_tag="ctg22_23"
                     /transl_table=11
                     /translation="MNFLIPQENYEERAQRIESPVLSAKNIREPAFTAGTTTTRHTAPM
                     SGFSG"
     CDS             5899..8007
                     /locus_tag="ctg22_24"
                     /transl_table=11
                     /translation="MGASGQATKPAARSVKTSKPNVIFILVDDMGWGDLDSNWSQQKLN
                     GRTVERKNEFKTPALSALAREGIQLRRHYSAAPVCAPARASLLLGVHQGNSRVVRNNRF
                     DQPIEDSHTLGTVMRDAGYDTAAIGKWGVGGGGQSHVPMTAGPHQRGFNYFYGILDHLA
                     GHFHYPSESRDVFEYNGYASNPEWKNIKDQVPQTAYSTDLFAARAKQWIVDQRKFARKT
                     GKPFFLYLAFPAPHGNLVVPGVPYPSGGGLKGGLQWVKKEGTESVNTAFDAKAEKNKDT
                     YIHPDNSRFPNDVAKRHSTMIRRVDDAVADLIRLLKDLKIDDNTMIVFSSDNGPHNEGG
                     ADSRHWHGAQNPQFFKSYGMMDGIKRDCWEGGMRVPTLVRWPARIPKGQISLHPGQFHD
                     WLATLADVAGVPVPARSDGVSLLPTLTGHADQQKPGIVYAEYNFAGKTPEYKDFLGEHK
                     GAQRGQQQIVFVDGLKGLRMGVKDADKDFMIFDTLNDPQESKDLASSKPELQARMKAAA
                     LSNRRASLPSKTVFDSALVPAVDVKGTVSPGLRWALYEGDFPWVPDFRQWKKPASAHGV
                     TPSPSVKMNGSDKRGVELTGYVKIPEDGAYTFYLTTDENKGSKAFVRLHGMELIDADKT
                     YEPGAEVSSDLGDRKNPVYLKAGLHPIRIGYVGNSGTASKLVLKWEGPGLSKKEIPASA
                     FSHGKESR"
     CDS             8016..8648
                     /locus_tag="ctg22_25"
                     /transl_table=11
                     /translation="MSDLYEYQAIDGSSKGPVDLVLLLRARNLGRLSNRTLVRKVPGGD
                     WRPLASFIPSMTVMDDDGEPSVLPDPGSEPGGADSGWSRKKYWICVIKAWCRFEGRAGK
                     GELHEVFSRVGVAWLAVAGVPSFAECGFFPSLVPWVELVSPLLYVVLAVLSIPLAATMV
                     RRLHDVGRSGFFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(8680..9645)
                     /locus_tag="ctg22_26"
                     /transl_table=11
                     /translation="MIFHHVFGLYALPAGVDTAWIAPQLTKAAPIFKICVPIFIFITGY
                     AMGWKTNSSPTFGSLIKTGFSHYFKFWKIYFLCLLLAILVSWAFPLPILPSVADMGWKN
                     GLLVVTGLRPCYPDWWYMALFAAATMALYPICAWITHHIAPVPSMAALLGVSLLFQSTA
                     HIPSLPGIAYSFPPFLPCFILGYMCAFLASRLSALSISQSLGAILLLALEILSIHLFSF
                     SKAKTLTVIFLSTLWCLPWITRKLRLTPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGT
                     QSISVVFIVTLVSSLLLAMAMQKLFNRMIPSNPQTQSKTL"
     CDS             9700..9795
                     /locus_tag="ctg22_27"
                     /transl_table=11
                     /translation="MLLKARNSKGREKAHLRRSSTDFQSEVNTLF"
     CDS             complement(10001..12784)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_28"
                     /sec_met_domain="Beta_elim_lyase (E-value: 9.2e-11,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 7e-174, bitscore: 569.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSLGYRTLDELIADIVPADIRMKAPLDLPAAKSETEALEELRS
                     ILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTAYTPYQPEIAQGRLEMLMNFQT
                     MVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANTFFVADTCHPQTISVIRTRAAF
                     QGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICDYTDFFSRVHATGALCVVAADL
                     MALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYMSCTDALKRRMPGRLIGMSIDT
                     LGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAFYAVYHGQEGLKRIGTEIHLK
                     TKSLYKALTEAGIAIKNKNFFDTLLLSVPGQADAMVQKALEAGYNIRRVDADHAAISLD
                     ETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQTPFCTEKAFNSYHSETEMMRY
                     IRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPEANSLHPFVPADQSEGIREMLS
                     VLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQKHAGEGHRNVCLIPTSAHGTNP
                     ASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLSCIMVTYPSTHGVYEQTIKELC
                     DIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNLHKTFAMPHGGGGPGIGPIGVA
                     EHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYLSMMGPDGLREATEMAILNANY
                     IAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLTVDDIAKRLMDYGFHGPTMSFP
                     VPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIINGTADKEDNVLKNSPHTAEMVSA
                     DEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDRNLVCTCDTVEEFSKAVEL"
     CDS             complement(12943..13323)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_29"
                     /sec_met_domain="GCV_H (E-value: 5.4e-48, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(13394..14392)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_30"
                     /sec_met_domain="GCV_T (E-value: 8.6e-79, bitscore: 255.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 3.7e-23, bitscore: 72.4,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVQYTGILDEHKAVRETCGIFDISHMGQFTVAGDSAAAWLNSML
                     TNDINKLNVGQGQYSVMLNDRAGVIDDLILYRMEPETFFVVVNASKIDEDFAWLSAHQP
                     AGVTLENHSDEYVGLAVQGPECGEVFSRVIPGVELPPRNGISRISAEGTDLIVCRTGYT
                     GEDGFEFFCPAKEGVKWFEAFLGAGAKPCGLGARDSLRLEMCYPLNGSDLSPDKTPLEA
                     GLGFFCALDTDFIGSDILREQKANGLSQRLAAIEYTGKGAPPRAHYAVHVPGGEAIGEL
                     TSGVLSPSLMKGIALAYLPAAHAKVGTELEIDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(14555..15676)
                     /locus_tag="ctg22_31"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVNPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVRDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(15735..16433)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_32"
                     /sec_met_domain="Peptidase_S11 (E-value: 2.5e-54, bitscore:
                     175.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALTGKVLFSHNGLQHRQVASTQKLVTAMVVMEHGSLDKKVVIQ
                     PSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARDTAGSVPRFAQLMNAKA
                     RQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNIICKRQYAFTRANGRTL
                     LLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIVVVLGCHPSRIWTESEN
                     LIRWALGYAV"
ORIGIN
        1 cgtgtgccgg gcttatggga acatgcagga gttccgcatg ttcccataaa cggttctgga
       61 agtttttaat attttttcgc aggaatgagg cggaaagctg caggggattg ggcggacttg
      121 atttgcaggg gcttggtcgg gtctttttga gtttccgggc caatggcgat gataagcctg
      181 tccttgggat gaatgacggt ggagttttca aagatgagcg tattggttcc gtccgtcagt
      241 ttccatccat ccaaaaggat gccggagttg cctgggttgt tgataatcac gttgccggtg
      301 cccggttcca atctgggggc gggctgctta agcctgaggc tttttgccag cttggcaaag
      361 gtgatttccg caatgcgccg tgcgccctgt tccgtagggt gcaacccgtc aacgtaccat
      421 tccggatggt cggagagcgg gtgcagcgcg tcaaagagac tgactttgta cttgcgcgct
      481 acggcggcaa tcagtttttc cgcttccggg cggttggcgg atgagccgtt gtccgagcct
      541 gcatatttac gtacgtccgg atagcagttg ccgggaaatg ccttcttgtt gagcgggccg
      601 cggtagtccg gccccagcag cccccaggca aagaaccgtg ttttgggatt ggcgtttttc
      661 cacgcatgaa gcagagcgtc atagcctttg gagaacagtt cggggttcca ccagcggccc
      721 gtgtcgttga tgccaaggtt gcagatataa atatccgcct tgaattccag ggcttgcttg
      781 tgttccctgg tgctgccgta ccagcgtcct gcctggcccg ggtagtcgcc tgccgttttt
      841 ccgggattgc cgaagcctct gacgtcaaag tccggcccca tgagtgtggc gagcacttgc
      901 ggataccggg tttctccggg tttaaggccg gtgccgaagg tgatactgtc ccccacgcag
      961 gctactttgg cgggagcagc ttgtgccgca atgcccagtg agagtgtggc tgtcagagaa
     1021 gcgaggataa gatgaaggtt catggagtga tggtgtggta aaagttattt tttcagaaca
     1081 ggttcgtccg tccggaaggg acgggcgggg agctggttgc cgttgaccag gttgggggtc
     1141 acgaaacggt tccagcaata ccgggcgtgt ttgggggatt ttacttccgg tgatgagagg
     1201 cggataacgg ctgtgttgcc tttcctgttt atgatttccg ctgcggcggg atgataagtt
     1261 ccgtccgtcc cggcaatttc aaactgggcc ggttctttgc cgtccgtggt ggtcagtccg
     1321 gcagcttgat ccagttgaac caggatgttg gaaccggaag gtttgaaggc cttgagggca
     1381 gggccttcac aggggatctt tttaccgtaa accttgttca gggcagtatt tcctgcacgt
     1441 tcccccacag ggcgcttgaa tggaggatga acgtcggaat tggtggagcc aagatcaatg
     1501 gtgttgacgc tgtaaacttt tggaacggtt ttggccacgg cgtcctgcat ttctcggaat
     1561 tccggccatc cggcacggat ttttgacggg tcgttgatgc gggggagctg gatcatgacg
     1621 aaaggcattt ccgggttacg gaaagctttt ctccaggagg agatcatggt tttcagcagc
     1681 atgctgtttt gggcattgtc aatgatctcc gcatcggatt cgccctgata ccagatgacg
     1741 cccgtgatgg ggagggccgt tgtccatgca atgccggatt cgtaaaggaa cgccggcttg
     1801 tagggatggt ccggagagcc ctggttcaga cgcggagaga tgtttttcct ggcccgtccc
     1861 ctcacccagt cggagataag gggggagtcc agccagtgat tgccgcgcag ggtgcggaag
     1921 ctgttgttgg cattaatgac ctgccggggg atccacgctg cgatttccga gcctcccagg
     1981 gaggagtgga tgatgcctac cggaatgccc agcccttcgc ggagtttttt cccgaagtag
     2041 tagcccacgg cagtcattgg ccctgaggtg gcgggagagc tggcggccca ttgcccttta
     2101 tagaagttgt ccgtggtgac ggcgtcaaag tctttcgcgg agtagggggc attgttggtg
     2161 tgggcttgcg gaacgttgtt gagcagacgg agctggtcgt ctccggaagc cgctatgtct
     2221 tctttggccg tcgtggtctg gttcagacgg aacagcatgt tggattggcc ggaagccagc
     2281 catacttccc ccacgagcac atcttccaat ttggcggagt ccccgttttg cacggccgcc
     2341 agcgtctggc ctgtggcgca gggaggcatg gggggcagcg tgacgctcca tttccccttg
     2401 gagtcggttt ttgttttcag ggcagtgttt ccaaaagtga cggttatttc cctgttgggg
     2461 gcggccgtac cggaaacggg aatgtttttc ccgtggggaa gtaccatatg ggaaccgaag
     2521 acccggtcga accggggcgt gtccgcccac gccgcatgaa gggcgatggc ggcagccagg
     2581 atgcatgaag tatggaggcg catggtttgg gggttatttg agaaggagtt catcccgcga
     2641 gaggccggtc agcctgccga gccgtttaat caggcgggtc atgatgaaga caagggctgc
     2701 caggatgggg attccgatga tcaggaagcc ccaccatgtg atgctgccga tggcggcgtt
     2761 gtaggccact tgctgttccg cttccggctg ttgtatgacg gaagacatga aagagaggct
     2821 caggaagaaa ttgccgatgg aggaggcaac cagtgtgccc gccagaatcc aggacgagtt
     2881 tgccagcagt ttctgataag cccgttcctc gccgttggcg gccaccgttt gttctatcct
     2941 gcgcacgtcg aataattccg gcgtgtagat aaacatgttg agaaggggcg tgccggcgga
     3001 ccgggagacg acgaccgccg cccccaggat aagggggatc agggcttctt ttccggcgaa
     3061 cagccagggt gtggcgctgt ggatgcgccc ttccggcccg atgacgaaga tgctaatgac
     3121 gcccgtcagc agcacgccgg ccatgcctac gccggacatc aggtcaaatt tcctggagac
     3181 ggccagggaa cggatgccat agacgagggg gagggaaagg gcgatgacga gagaccatac
     3241 cgggccgata tgccagaaac tttctccctc cggacgttcc aagggattgg cggggcctgc
     3301 gctgcagtag tccagaatca gtaccgggag gaggatgttg atgaaaattc ccagcaggga
     3361 ggactgtgat ttgtttggcg ttttatccat gaattcggag ggaaatattt gtaccatatg
     3421 cgaatgcgcc cctgcaagtt gcaaccccgt gtgtgacagt aaagaccaga agcggggaga
     3481 gccgtttttt tattcgcagg cggctttgcg gaaatcgtgg catctacggt atcttccgtt
     3541 cttttggctg gacacgggag ggaagaatgt tcagcttctt ccgtgacttt gacagatcat
     3601 ttttccccat gactcaaaca tcttcttttt cggctcttgg tatttcaccg gagattctgg
     3661 aggctatcga agtgctcggc ttcgatactc cttcctccat tcaggagcag gcgattcccg
     3721 ccgcgatcag tggggccgat attgtggggc tgtcccatac gggttccgga aaaacgcttg
     3781 ccttcgccat tccggccctg gagtgcattg agcctgagga acgctgcgtt caggtgctgg
     3841 ctctttgtcc tactcgggaa ctggccgttc agatttgccg ggaggtggac aagcttgctt
     3901 tatttatgga cggcgtttcc gccgtcccca tttacggggg ggcttctttc cgtccgcaac
     3961 tggacgccct gcgccgcggg gtgcagtttg tggtggggac gcccggacgc gtcatggatc
     4021 tgatggagtc gggggcatta aggctggacg gactccgcat gctgattctg gatgaggcgg
     4081 acgagatgct ggatatgggt tttctggaag acatcgaacg cattgcggag gccatgccgg
     4141 aaacgaagca gaccctgttt ttttccgcta ccatgtctcc ggaaatcaac cgtctggtga
     4201 gcaggttcat gaaggagccc atccagattt ccattgaacg gcctacgctg acggtgccta
     4261 ccattgaaca ggtttattac gaagtggtgt tttcctcccg gattgaggta ctcagccggc
     4321 tgcttgacac cggaaagatt aaaatggggc tggtgttcgc caataccaaa aaggtggtgg
     4381 atgacgtggt ggacggtctg acggcccgcg gttatccggt ggatcgcctt catggggata
     4441 tgccccagat gatgagggag cgcgtgatgg attccttccg caaggggagc ctgcgccttc
     4501 tggtggcgac ggatattgcc gctcgcggcc tggatgtgga cgatgtggat gccgtggtga
     4561 attttgaatt gccgcgtgat ccggaggatt acgtgcaccg catcggccgc acggcacgcg
     4621 ccggccgcaa ggggaaggcc atcacttttg tggggcgccg tgatttttcc ctgatgagcc
     4681 gcattgaacg tttcatcggc gttaagttga ctccggaacc tgtgttgact gccgttcagg
     4741 tggaccagct ccggacagag tccctggtgg atgatatcct ggaacgtctc aagccggatg
     4801 ccgtgctgcc ggaggaattg aaggaagtgg aggctgcgcc ggaggccatg gctgcggccc
     4861 tgtttgactt gctccgggaa cgtacgcacc gggaagtgca gcccattccg gaagacaagc
     4921 ccgcccgcag ggcgcggcgt atgccgcaga ccggggagga ggcggagagc ccgcagaagg
     4981 gtgattcctg gcagcataag ggggatacgg ttacgctgtt tatgaatgga ggccggatga
     5041 ttggcttgcg gcccaaagac atagccgggt tattttacaa tacggtggaa atggaaaagg
     5101 gagccgtggg cgatatccgg attttcccca agcattccct gatagaagtg gacgcttccg
     5161 tggcgcccct gcttctggag gccctggcga cggctaccgt ctgcggctat gaagttaatg
     5221 tccgtgaaga caagggggct ccggaatatt ccggaactcc gcgctcttcc cgccgcaatg
     5281 gaggattccg caacagttac cgcggagagc gggaccgcag tgaccggagc ggattcaggg
     5341 gaaaccgcgg gggcttccgc agtgaccgcg gcgaacgctg gggcgaacgt tcccgcaggg
     5401 acgacaggaa gaagcgtttc tgatgccttc gctattccgg acagggttat taacgctgtt
     5461 ccggaattgg cgcggacatt ttggaacgtt ccggttcatg attgctgttt ccgccggttt
     5521 ctgtattttc tgcccggcgg ggggattgcc gnnnnnnnnn nattcaggat aaagcatggc
     5581 cgggcggggc tggtgaccgg ggcgccggga atgcaggagg aattttctcc cattcctggc
     5641 ttcagccaga aaagccgctc attggtgcag tatggcgggt tgtagttgtt ccggctgtga
     5701 aggctggttc cctgatgttt tttgccgata atactggcga ttcaatcctc tgtgcccttt
     5761 cctcgtaatt ttcttgaggg atgagaaaat tcatgtaaga taacgcttta ttttaacgtc
     5821 ttttttagag tctattttct ttgaatcatg aagctggtat ctttactatc cgttcttctg
     5881 acttccctgg ttccgtgcat gggtgcttcc gggcaggcaa cgaagccggc tgcccggtct
     5941 gtcaaaactt caaaacccaa tgttattttc attctggtgg acgacatggg ctggggtgat
     6001 ctggattcca actggagcca gcagaagctg aatggccgga cggtggagag aaagaacgag
     6061 ttcaagactc ctgccctgtc cgctctggct cgggagggga ttcagctgcg ccgtcattat
     6121 tccgccgctc cggtttgcgc tccggcgcgc gcctccctgc tgctgggggt gcaccagggg
     6181 aattcccgcg tggtgagaaa caaccgtttc gaccagccta ttgaagattc ccatacgctg
     6241 ggtaccgtga tgcgtgatgc cgggtatgat actgccgcca ttggcaaatg gggtgtaggc
     6301 ggcggaggcc agagccatgt gcccatgacc gccggccccc atcagcgggg attcaattat
     6361 ttttacggta tcctggacca tttggcaggg cattttcact atccttccga atcccgtgac
     6421 gttttcgaat acaacggtta cgcttccaat cccgagtgga aaaatatcaa ggaccaggtg
     6481 ccccagacgg cttattccac ggatttattt gccgcccgcg ccaagcagtg gattgtggac
     6541 cagcgcaagt tcgcccgcaa gaccggaaag ccgtttttcc tgtacctggc ttttccggcg
     6601 ccccacggca atctggtggt tccgggggtt ccctatcctt ccggcggcgg attgaaagga
     6661 ggcctgcaat gggtaaagaa ggaaggcacg gaatccgtga atacggcttt tgacgccaag
     6721 gcggaaaaga ataaggatac ctatattcat ccggacaatt cccgtttccc gaatgatgtg
     6781 gccaaacgtc attccaccat gatccgccgc gtggacgatg ccgtggctga tttgatccgt
     6841 ctgctgaaag atttgaagat tgacgataat acgatgatcg ttttctcgtc cgacaatggc
     6901 ccccacaatg agggtggcgc cgactccagg cactggcacg gagcgcaaaa tccgcagttt
     6961 ttcaagagtt atggcatgat ggacggtatt aagcgcgatt gctgggaagg aggcatgcgc
     7021 gtgcctacgc tggtacgctg gcccgcccgc attcccaaag ggcagatcag cctgcatcct
     7081 ggacagttcc atgactggct ggctacgctg gcggatgtcg ccggggtgcc ggttccagcc
     7141 cgcagtgacg gcgtttccct gctgccgacg ctgaccggtc atgcggacca gcagaagccc
     7201 ggcattgttt atgccgaata taatttcgcc ggcaaaacgc cggagtataa ggatttcctg
     7261 ggcgaacaca agggagcgca gcgaggccag cagcagattg tttttgtgga tggattgaaa
     7321 ggcttgcgca tgggggtgaa ggatgcggac aaggatttca tgatttttga tactttgaat
     7381 gatccgcagg aaagcaaaga tctcgcatcc tccaagccgg aacttcaggc ccgcatgaaa
     7441 gccgccgctt tgtccaatcg ccgggcttcc cttccttcca aaacagtgtt tgattctgcg
     7501 ctggtgcctg ccgtggatgt gaagggaacc gtttctcccg ggttgcgatg ggccttgtat
     7561 gagggggatt ttccctgggt accggatttc cgccagtgga agaagcctgc ttccgcccat
     7621 ggcgtgacgc cttccccatc cgtgaaaatg aacggttcgg acaagcgcgg tgtggagctg
     7681 acgggatatg tgaagattcc agaggacgga gcatatacgt tttatctgac cacggatgaa
     7741 aataagggca gcaaggcttt tgtccgtctg cacggcatgg aattgattga cgcggacaaa
     7801 acttatgagc cgggggccga ggtctcctcc gatctgggtg accggaagaa tcccgtttat
     7861 ttgaaagctg gacttcatcc catccgcatt ggctatgtgg ggaactccgg tactgcctcc
     7921 aaactggttt tgaagtggga aggtcccggt ttgtccaaga aggagattcc cgcctccgcc
     7981 ttcagccacg ggaaggaatc caggtaagcg tccccatgag cgatctgtac gagtatcagg
     8041 caattgacgg ttcttccaaa ggcccggttg acctggtgct tttgctgcgg gcccgtaacc
     8101 tcggccgcct gtccaaccgg actttggtcc ggaaggttcc cggcggagac tggaggcctc
     8161 tggcctcttt tatcccctcc atgactgtta tggatgatga tggggagccc tccgttctgc
     8221 cggatcccgg ttcagagcct ggaggcgccg actccggctg gagcaggaag aagtactgga
     8281 tatgcgtcat caaggcatgg tgccgttttg agggccgtgc cgggaaaggg gagctgcacg
     8341 aggttttttc cagagtgggg gttgcgtggc tggccgtggc gggagtcccc tcttttgcgg
     8401 aatgcggttt tttcccgtcc ctggttccgt gggttgagct ggtttcccct ctgctgtacg
     8461 tggtgctcgc cgtgctgtct attccgctgg cggctaccat ggtccggcgt ctgcatgatg
     8521 tcgggaggag cggctttttc ctggtttttc tggccgttcc cttcataggg tggctgctgt
     8581 tgtggtattt atcccatggg gaaagccgga ttggagaaaa taagtacgga gatccccctt
     8641 ggaattaaga ggtgttggaa tccggacctt gtaaagttgc tacaaagttt ttgactgcgt
     8701 ttgcggattt gagggaatca tccggttaaa aagtttttgc atggccatgg ccagcagaag
     8761 ggaggagacc agcgtcacga tgaatactac gctgatgctt tgggttccat agaggtccca
     8821 gctgaagtgg tagccgaaaa tgaatctgtg attcagccac ataagtgcgg aataagttcc
     8881 cagcagcgtc aagagcggtg tgaggcggag tttccgggtt atccaaggca gacaccagag
     8941 ggtggagaga aagataaccg tcagggtttt ggcttttgaa aaactgaaga gatggatgga
     9001 tagtatttca agagccagca acaggattgc tcccaagctt tgggaaattg aaagagcaga
     9061 gaggcgtgaa gccagaaagg cgcacatgta gccgagaatg aagcagggca ggaaaggagg
     9121 gaaggaatag gcgattcccg gcaggctggg aatgtgggcc gtactttgaa ataaaaggga
     9181 cactcccagc agagctgcca tggacgggac aggcgcaatg tgatgcgtga tccacgcaca
     9241 gattggataa agggccatgg tggctgccgc gaaaagagcc atgtaccacc agtcgggata
     9301 acagggcctc aatcctgtta cgacaagcag gccatttttc caacccatgt cggcaacgga
     9361 tggcaaaatg ggcaagggga atgcccagga aaccagaata gccagaagga ggcataagaa
     9421 ataaattttc cagaatttaa agtaatggga aaagcctgtt ttaatgaggg aaccgaaggt
     9481 tggggatgaa tttgttttcc atcccatagc gtaccccgtg atgaaaataa aaatgggcac
     9541 gcaaatttta aagatgggag cggctttggt aagctgggga gcaatccatg ccgtatccac
     9601 acctgcgggt agagcgtata agccgaagac atgatgaaag atcatgaaga gaattccata
     9661 ccctttgagg atagcggaat cttccctgga aaaagaaaga tgctgttgaa ggccaggaac
     9721 agtaagggca gagaaaaagc tcatctgaga cgtagctcaa cggatttcca atccgaagtc
     9781 aacactctat tttgagaaca aatgggtcat caaaatgaaa ggggaggaaa agcggggtgg
     9841 gagaaatgtt ccttttttct ttttcaaccc atattgtttt tgggcttaat tgttttctgg
     9901 atatgtttgc tctttcggat tggaaatccg attcttgaac ataagaaaaa ggctgctcca
     9961 aatgaatgga acagcctttt tgaaaggaag gatgagattt ttataactct acggccttgg
    10021 agaattcctc caccgtgtcg caggtgcaga ccagattgcg gtctccgtac acattatcca
    10081 cccggcctac atacggccag aatttgtgaa taaggagacc ggagaccgga taagccgctt
    10141 cactgcggga gtaggggtgc cgccattcgt cggcggagac catttctgcg gtatggggcg
    10201 agtttttcag gacgttgtct tccttgtctg ccgtaccgtt gataatggcc gtgatttccg
    10261 catgaatgcg ttccatggct tcaatgaagc ggtccagttc ttttttgggt tccgattccg
    10321 tcggctccac catcagggtg cccggaacgg ggaaggacat ggtggggccg tggaagccgt
    10381 agtccatgag ccttttggca atgtcatcca ccgtgaggcc ggcgtcatga gtgagctggc
    10441 gcggatccag aatgcattca tgcgccacca gccccttgtt gccggagtag agaaccggga
    10501 agagatgtcc gagtttcttg gcaatgtagt tggcgttaag gatggccatt tccgtggctt
    10561 ccctgaggcc gtccggcccc atcatggaga ggtacatcca gcagatggcg gcgatggagg
    10621 cgcttcccca cgccgcagac gctacggccc cttcttcatg gcccagcgtg aggtgcccgg
    10681 gcaggaaggg tacgaggtgt tccgctacgc cgatgggccc gatgccggga ccgccgccgc
    10741 cgtgcggcat ggcaaaggtt ttatgcaggt tcaggtggca gacgtccgcg ccaatgcagc
    10801 cggggcaagt cagacctacc tgggcattca tgttggcgcc gtccatgtac acctggccgc
    10861 cattggcatg gacgatgtcg cagagttcct tgattgtctg ttcatatacc ccgtgcgtgg
    10921 aggggtacgt gaccatgatg caggagagat tgtccttatg ggcttccgcc tgggatttca
    10981 ggtctgccat gtcgatgttg cctctttcgt cgcatttgac gggcaccacc ttgaggccgg
    11041 ccatggcgga ggatgcggga tttgttccgt gggcggaggt gggaatgagg cagacattgc
    11101 ggtggccttc tccggcgtgc ttctggtagc ggcggatggc cagtagcccg gcatattccc
    11161 ctgcggcgcc ggcgttgggc tggagggata cggcggcaaa gccggtgatt ttcgccagac
    11221 ggtcggacag gacggagagc atttcccgga tgccttccga ctggtccgcc ggaacaaagg
    11281 gatgcaggga gttggcttcc ggccacgtga tgggaatcat ttcagaggcg gcgttcagct
    11341 tcatcgtgca ggagcccaga gggatcatgg cttcatttag agccaggtcc cgggattcca
    11401 ggcggcggat gtagcgcatc atttccgttt cggaatggta ggagttgaaa gccttttccg
    11461 tgcagaaagg cgtctggcgc gtgtggacgg gatcccaggc aggagcgtcg caatcgcagg
    11521 cagcggatgt ttccgcacct gcaagggcgg aggccagtgc cgctatatcc gcacaggttg
    11581 cggtttcatc cagagagatg gctgcgtggt cggcatccac cctgcggatg ttgtacccgg
    11641 cttccagggc tttttgcacc atggcgtccg cttgtccggg aacggacagc agcagggtgt
    11701 caaagaagtt tttgttttta atggcgatgc cggcttccgt gagcgccttg tacaggcttt
    11761 tggttttcaa gtggatttcc gtgccgatgc gtttgaggcc ttcctgtccg tggtatacgg
    11821 cgtaaaaggc ggcaagcacg gccaggagca cctgggcggt gcagatgttg gaggtcgcct
    11881 tgtcgcggcg aatatgctgt tccctcgttt gcagggccag gcggtaggcc gggcggccca
    11941 gggtatctat ggacatgccg ataaggcggc cgggcatgcg gcgtttgaga gcgtccgtgc
    12001 aggacatgta ggcggcatgg gggccgccga agcccattgg gatgccgaag cgctgcgtgt
    12061 tgccgatgca gatatcggct ccgaaggcgc cgggttcccg gatgacggta agggccatga
    12121 gatccgccgc cacgacgcag agcgcgcccg tggcatgcac gcgggaaaag aagtccgtgt
    12181 agtcgcagat gcggccgagc gtgtccggat attggacaag cactccggcc agatccgcac
    12241 cgatggatgc ggggtcaaag gatgagcaat ctcccacgat gatgttaacg ccctggaagg
    12301 cggcgcgggt acggatgacg ctgatggtct ggggatggca ggtgtccgcc acaaagaagg
    12361 tgtttgcttt ggggcgcgcg ttccggcaca tggtgacggc ttctgctgct gcggtgcctt
    12421 catccagcag ggaggcgttc gctaccggca gccctgtcag ggaagagacc atggtctgga
    12481 aattcatgag catttccagc cgtccctggg cgatttccgg ttgataaggg gtgtaggccg
    12541 tgtaccagcc ggggttctcc agtacattgc ggaggatgac ggagggagtg atggtgccgt
    12601 aatagccctg gccaatgaag gttttcagga gcttgttttt ccgcagaatg gaacggagtt
    12661 cctccagggc ttccgtttcc gatttggctg cgggcaggtc cagcggggcc ttcatgcgga
    12721 tatctgcggg gacgatgtcc gcaatgagtt cgtcaagcgt ccggtagccg aggctgtcaa
    12781 gcatttcccg gcgttcttcc ccctgggggc cgatgtgccg gctggcaaaa tctgagtggg
    12841 tattcatgtg gtatctctgg ctggtaatag cgtccggccg cgggacgggc caaacaaaat
    12901 gccccgggat ggaatcaccg gggcggggga ggaaagaatg gttcaggagc agtattcctc
    12961 gtaatccgtg gcgttcatca tatcttccgt ttccgtggga acgtccaggc ggattttgta
    13021 cagccagcct gcgccgtagg ggtcggagtt aatgagggag gggtcattgg aaagctcttc
    13081 attcacttcc aggatttctc ctgaaacggg ggtgtacacg tcgctggcgg ctttgacaga
    13141 ttccacgacg gcgacggggt cgccggccgc gacggtggcg cctacttcgg gaaggtctac
    13201 aaagacgaca tcggagagtt cggcctgggc atggtctgaa atgccgatgg tgccgatgtc
    13261 cccgtcaatt tcaatccatt cgtgatcctt ggaatacagc agattttctg gtacgtcgtg
    13321 cataagatgt aattgtttga agtgagagtg tagtaaaatg aggtgtttgt cagtttattt
    13381 ttgcgccgtc gtgtcagcct tttttataaa agggtttttt tacgaccacg gccggaaatt
    13441 tccttcccct tacgtcaatt tccagctccg tgccgacctt ggcatgggcg gcaggcaggt
    13501 aggccagggc aatacccttc atcagcgaag gagagagcac gccgctggta agttctccga
    13561 tggcttctcc gccggggacg tgaacggcat aatgggcgcg gggaggggct cccttgccgg
    13621 tgtattcaat agccgccagc cgctggctga gaccgttggc tttttgttcc cggaggatat
    13681 cggaaccgat gaaatccgta tccagcgcgc agaagaagcc gagcccggct tccagaggcg
    13741 tcttgtccgg agagaggtcg gagccgttca gaggatagca catttccaga cgcagactgt
    13801 cgcgggcgcc caggccgcag ggtttggctc ctgctccaag aaaggcttca aaccatttga
    13861 cgccttcctt agccgggcag aagaattcaa aaccatcttc cccggtatag ccggtgcggc
    13921 agacaatgag atccgtccct tccgccgaga tgcgggaaat tccattgcgg gggggaagtt
    13981 ccacaccggg gatgacgcgg gagaatactt ctccgcattc gggaccttga acagccagcc
    14041 ccacgtattc gtcggagtgg ttttccaggg ttacgcctgc aggttgatgg gcggaaagcc
    14101 atgcgaagtc ttcatcaatc ttggaggcgt tcaccactac gaagaaggtt tccggttcca
    14161 tccggtacag gataaggtcg tcaatgactc cggctctgtc attgagcatg acggagtatt
    14221 gcccctgccc tacattcaat ttgttgatgt cattggtcag catggagttc agccaggccg
    14281 cggcagaatc gccggctacc gtgaactgcc ccatgtggga gatgtcaaag atgccgcagg
    14341 tttcgcgcac tgctttgtgt tcgtccagaa tgccggtgta ctgcaccggc atattccagc
    14401 cggcaaaagg aaccattctg gctcccagtt caacgtgttt agctgccagg ggggtggatt
    14461 tgacgtctgt atcagtcatg aggcgatgtg aaggttgtga gcaatctgcc ccttatatca
    14521 gtaaaagtca atggaattcc ggtaacgctt ccgtctagac attgaagcgg aattcgataa
    14581 cgtccccgtc tttgacgaca tattcttttc cttcgatgcg cagcttgccg tgttccctcg
    14641 ctccggcctt gccgccacag gaaaccaggt cgtcgtagtg cactacctct gcggcgataa
    14701 aaccgcgttc aaagtccgtg tggataacgc cggccgcctg aggtgctttt gccccggacg
    14761 gaatggtcca ggcccgcgtt tccttgattc ccgtggtgag gtaggtgcgc aggcccagaa
    14821 ggtggtacac ggcccggatg aggtcggaaa cgccggaatc ccgcacgccc agggattcca
    14881 gaaattcgcg ggattcttcc tccgagacgt cgatgagttc ctcttcaatc cgggcagaga
    14941 tgacaatggc ttccgcgttg tggtgttccg ctacgtattt tttcacctgg gagacgtagg
    15001 gatgggcgtc cgggttggag atggcgtccg ccagttcgtc ttcattgaca ttgcaggcga
    15061 aaatgctttt tttatccgaa agcagctgga aggaatggag cagcttgcgt tcatcgtcgt
    15121 ccagctgcgg ttcaagggtg agggcgggat tgccttcgtt caggtggggc aggagtttgg
    15181 tgatgagggc cacttcggcc ttggcttcct tgtcgccgct gcgtgccttg cgttcgcggg
    15241 aagagagtct cttttccatg gtggcgatat ccgccagaat gagttccgag ttgatgatgt
    15301 caatgtcgcg cagaggattc acggaaccga gttcatgaat gatatcatca ttgtcaaagc
    15361 agcggactac ctgcacgatg gcgtccactt cacgaatgtt cgccagaaac tggttgccca
    15421 ggccggcgcc ttccgaggcg cccttgacca ggccggcaat atccacgaat tcaataagcg
    15481 tggggatgat tttttcagaa ccggacatgt cggaaagaac ctgcaggcgg ggatccggga
    15541 ctgttaccat acccacgttc gggtcaatgg tgcagaaggg atagttggcc gcctgggcct
    15601 tgcgcgtccg ggtgaccgca ttgaatagag tggatttgcc gacgttgggg agacctacaa
    15661 tacctgcctg taacataggc aggactgata gcgggtcacg ccgtgaaagt caaataccaa
    15721 ttgccgacgg gcatttatac ggcgtatccc agagcccatc tgatcaggtt ttccgattcc
    15781 gtccagatac gggacggatg gcagccgagg acgacgacga tgacatggcg cccgttgacg
    15841 ccggctgagg aaaccaggca gcgtccggcg gcgttcgtgt atccagtttt catcccggta
    15901 acccaggggt tctgggtgag cagcttgttg gtgtttctca acagaagcgt tctgccgttg
    15961 gcgcgggtaa aggcatattg gcgtttgcag ataatattgc gcagttccgg gttgcggtac
    16021 acgtaatagg cgcagcgggc catgtcaatg gcagtggaat attgatctgc cgggaggccg
    16081 ttgggattgg cgaagcgtga gttgtacatg cccatctgcc gggctttggc attcatcaac
    16141 tgggcgaaac ggggaacgga acccgccgta tcgcgggcca gcgccagggc tacgtcgttg
    16201 aaactgcgga tcatcatggc attgagcagt tcgcggcgtg aatagacttc ccccgcccgg
    16261 aatcccagtt tggtggggtc cgccttggta tcggaaggct ggatgaccac ttttttgtcc
    16321 aggctgccgt gttccatcac gaccatggct gtcacgagtt tctgcgtgct ggctacctgg
    16381 cggtgctgga ggccgttgtg ggaaaagagc actttgccgg taagggcgtc catgacgcag
    16441 gcactggcgc agcggggcgt gcgcggggcg cttgagggga tggctacagg gcgtgtgggg
    16501 aaattggccg gtcgggggag
//
