## Tue Jul  9 18:00:06 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_036756085.1/GCA_036756085.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_036756085.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_036756085.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NFPJHIIC_00001	111105.HR09_03760	7.12e-126	370.0	COG1002@1|root,COG1002@2|Bacteria,4NIMJ@976|Bacteroidetes,2FQV9@200643|Bacteroidia,22ZSZ@171551|Porphyromonadaceae	976|Bacteroidetes	V	restriction	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00002	111105.HR09_03765	1.83e-23	102.0	COG1061@1|root,COG1061@2|Bacteria,4NE28@976|Bacteroidetes,2FMAJ@200643|Bacteroidia,22ZYX@171551|Porphyromonadaceae	976|Bacteroidetes	L	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,ResIII,T5orf172
NFPJHIIC_00003	877414.ATWA01000036_gene1437	0.0	1303.0	COG1061@1|root,COG1061@2|Bacteria,1U2DR@1239|Firmicutes,24CD7@186801|Clostridia,26A3A@186813|unclassified Clostridiales	186801|Clostridia	L	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,ResIII,T5orf172
NFPJHIIC_00004	357809.Cphy_0959	2.53e-133	394.0	28MIB@1|root,2ZAV3@2|Bacteria,1VEA9@1239|Firmicutes,24XM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
NFPJHIIC_00005	1410612.JNKO01000021_gene2808	1.22e-190	551.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,2PQR5@265975|Oribacterium	186801|Clostridia	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24,HTH_DeoR
NFPJHIIC_00006	657322.FPR_09610	3.05e-48	154.0	2CZEX@1|root,32SNV@2|Bacteria,1VEBP@1239|Firmicutes,24Q7Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00007	657322.FPR_09630	1.88e-52	165.0	COG1925@1|root,COG1925@2|Bacteria,1VNNY@1239|Firmicutes	1239|Firmicutes	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NFPJHIIC_00008	657322.FPR_09640	0.0	1040.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia,3WN1N@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NFPJHIIC_00009	657322.FPR_09650	0.0	894.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,3WKXE@541000|Ruminococcaceae	186801|Clostridia	H	PRD domain	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
NFPJHIIC_00010	1408437.JNJN01000011_gene1146	1.65e-123	363.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,25VK7@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFPJHIIC_00011	1123313.ATUT01000004_gene91	2.63e-269	741.0	COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,3VNX5@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NFPJHIIC_00012	657322.FPR_09670	6.24e-168	470.0	COG1349@1|root,COG1349@2|Bacteria,1V25D@1239|Firmicutes,24GWY@186801|Clostridia,3WRTQ@541000|Ruminococcaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NFPJHIIC_00013	657322.FPR_09680	9.07e-177	492.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
NFPJHIIC_00014	657322.FPR_09690	1.09e-151	427.0	COG1309@1|root,COG1309@2|Bacteria,1VJYD@1239|Firmicutes,24SNN@186801|Clostridia,3WP6U@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00015	657322.FPR_09700	3.68e-169	504.0	COG5263@1|root,COG5263@2|Bacteria,1V1J6@1239|Firmicutes,24G0Y@186801|Clostridia	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00016	97138.C820_00139	3.36e-18	84.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
NFPJHIIC_00017	657322.FPR_09720	1.82e-164	460.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,24G6Q@186801|Clostridia,3WJ5E@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
NFPJHIIC_00018	657322.FPR_09730	1.99e-299	817.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3WHWQ@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFPJHIIC_00019	718252.FP2_13750	0.0	1637.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFPJHIIC_00020	657322.FPR_09750	0.0	1541.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WHAB@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFPJHIIC_00021	657322.FPR_09760	4.29e-135	382.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,3WG96@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
NFPJHIIC_00022	657322.FPR_09780	5.68e-287	794.0	COG1418@1|root,COG3599@1|root,COG1418@2|Bacteria,COG3599@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
NFPJHIIC_00024	657322.FPR_09800	4.75e-143	413.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3WHQY@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
NFPJHIIC_00025	718252.FP2_14030	4.28e-280	769.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHTA@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NFPJHIIC_00026	748224.HMPREF9436_01116	2.33e-185	521.0	COG1961@1|root,COG1961@2|Bacteria,1VX7M@1239|Firmicutes,252DN@186801|Clostridia	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00027	657322.FPR_25010	1.19e-186	518.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFPJHIIC_00028	657322.FPR_25000	9.76e-256	701.0	2DW54@1|root,33YJJ@2|Bacteria,1VXQX@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00032	457415.HMPREF1006_00066	4.58e-160	490.0	COG1353@1|root,COG1353@2|Bacteria	2|Bacteria	J	crispr-associated protein	csm1	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
NFPJHIIC_00033	657322.FPR_24960	1.16e-102	297.0	COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,24R4K@186801|Clostridia,3WQNQ@541000|Ruminococcaceae	186801|Clostridia	L	Pfam:DUF310	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
NFPJHIIC_00034	657322.FPR_24950	1.5e-159	447.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia,3WPKV@541000|Ruminococcaceae	186801|Clostridia	L	RAMP superfamily	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NFPJHIIC_00035	657322.FPR_24940	7.77e-234	643.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia,3WPNR@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NFPJHIIC_00036	657322.FPR_24930	3.86e-283	773.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia,3WPY4@541000|Ruminococcaceae	186801|Clostridia	L	RAMP superfamily	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NFPJHIIC_00037	657322.FPR_24920	1.44e-178	497.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia,3WKX0@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
NFPJHIIC_00038	657322.FPR_24910	8.19e-158	455.0	COG1517@1|root,COG1517@2|Bacteria,1UYKN@1239|Firmicutes,249ZK@186801|Clostridia,3WKZT@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated (Cas) DxTHG family	-	-	-	-	-	-	-	-	-	-	-	-	Cas_DxTHG
NFPJHIIC_00040	657322.FPR_24890	8.15e-149	418.0	2EIAU@1|root,33C28@2|Bacteria,1VM81@1239|Firmicutes,2527Y@186801|Clostridia,3WKZU@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated (Cas) DxTHG family	-	-	-	-	-	-	-	-	-	-	-	-	Cas_DxTHG
NFPJHIIC_00042	657322.FPR_24870	2.49e-312	851.0	COG3505@1|root,COG3505@2|Bacteria,1UZB3@1239|Firmicutes,24915@186801|Clostridia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
NFPJHIIC_00043	657322.FPR_24860	1.56e-259	714.0	COG2885@1|root,COG2885@2|Bacteria,1VHI1@1239|Firmicutes,24SNI@186801|Clostridia	186801|Clostridia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
NFPJHIIC_00047	391295.SSU05_0325	4.38e-70	227.0	COG1073@1|root,COG1073@2|Bacteria,1V6QE@1239|Firmicutes,4IJ93@91061|Bacilli,1WTYG@1307|Streptococcus suis	91061|Bacilli	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
NFPJHIIC_00048	1235792.C808_00423	6.17e-143	413.0	COG0657@1|root,COG0657@2|Bacteria,1TSTM@1239|Firmicutes,24NKW@186801|Clostridia	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NFPJHIIC_00049	1211844.CBLM010000036_gene2076	1.04e-07	49.3	2DCYS@1|root,2ZFV3@2|Bacteria,1W2YY@1239|Firmicutes,3VUAC@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00050	1232436.CAPF01000061_gene1317	2.24e-33	123.0	COG1309@1|root,COG1309@2|Bacteria,2HW77@201174|Actinobacteria,4CY2T@84998|Coriobacteriia	84998|Coriobacteriia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00051	411483.FAEPRAA2165_02541	3.61e-50	159.0	2CZEX@1|root,32T68@2|Bacteria,1VB18@1239|Firmicutes,24MZP@186801|Clostridia,3WPUQ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00052	657322.FPR_02930	0.0	950.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NFPJHIIC_00053	718252.FP2_26960	3.39e-17	73.9	28ZHZ@1|root,2ZM9E@2|Bacteria,1W50Q@1239|Firmicutes,255D3@186801|Clostridia,3WR9B@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00054	657322.FPR_02950	9.75e-81	240.0	COG1321@1|root,COG1321@2|Bacteria,1VH4R@1239|Firmicutes,24SPR@186801|Clostridia,3WMMY@541000|Ruminococcaceae	186801|Clostridia	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repress,MarR_2
NFPJHIIC_00055	1378168.N510_01236	1.65e-43	163.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
NFPJHIIC_00056	657322.FPR_02960	8.17e-222	615.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	envE	-	3.1.4.46,3.2.1.18,3.2.1.8	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	-	R01030,R01470,R04018	RC00017,RC00028,RC00077,RC00425	ko00000,ko00001,ko01000,ko02042	-	GH33	-	GHL10,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin,SLH
NFPJHIIC_00057	657322.FPR_02970	0.0	1150.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WH64@541000|Ruminococcaceae	186801|Clostridia	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
NFPJHIIC_00058	657322.FPR_02980	3.61e-286	785.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1VE78@1239|Firmicutes,25DNA@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
NFPJHIIC_00059	657322.FPR_02990	2.41e-213	591.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NFPJHIIC_00060	657322.FPR_03000	0.0	1241.0	28N4Z@1|root,2ZBA9@2|Bacteria,1V60W@1239|Firmicutes,24HJB@186801|Clostridia,3WP63@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00061	657322.FPR_03010	0.0	1383.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGVQ@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NFPJHIIC_00062	657322.FPR_03020	0.0	952.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3WGMX@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
NFPJHIIC_00063	657322.FPR_03030	1.15e-115	332.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3WJC2@541000|Ruminococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
NFPJHIIC_00064	748224.HMPREF9436_02483	1.57e-107	312.0	COG1309@1|root,COG1309@2|Bacteria,1V7J5@1239|Firmicutes,24JZZ@186801|Clostridia,3WKDX@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00066	657322.FPR_03060	0.0	1931.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WHMA@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
NFPJHIIC_00067	657322.FPR_03070	1.61e-221	611.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3WG9A@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NFPJHIIC_00068	657322.FPR_03080	4.37e-264	724.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFPJHIIC_00069	657322.FPR_03090	1.3e-239	659.0	COG0673@1|root,COG0673@2|Bacteria,1UGN1@1239|Firmicutes,249ZU@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFPJHIIC_00070	657322.FPR_03100	1.09e-249	684.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NFPJHIIC_00071	748224.HMPREF9436_00914	3.74e-163	466.0	2DV4W@1|root,33U20@2|Bacteria,1VUE7@1239|Firmicutes,25097@186801|Clostridia,3WP8N@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00072	748224.HMPREF9436_00913	0.0	1167.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG86@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NFPJHIIC_00073	657322.FPR_21670	3.52e-124	354.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NFPJHIIC_00074	657322.FPR_21660	0.0	897.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
NFPJHIIC_00075	657322.FPR_21650	0.0	901.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NFPJHIIC_00076	657322.FPR_21640	1.51e-94	276.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WJCC@541000|Ruminococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NFPJHIIC_00077	657322.FPR_21630	2.11e-272	744.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NFPJHIIC_00078	657322.FPR_21620	0.0	1266.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3WH8C@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NFPJHIIC_00079	657322.FPR_21610	0.0	1187.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NFPJHIIC_00080	657322.FPR_21590	1.7e-115	330.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,3WISH@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
NFPJHIIC_00081	657322.FPR_21580	2.2e-117	337.0	COG0482@1|root,COG0482@2|Bacteria	2|Bacteria	J	sulfurtransferase activity	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NFPJHIIC_00082	657322.FPR_21570	4.06e-93	271.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NFPJHIIC_00083	657322.FPR_21560	0.0	1431.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NFPJHIIC_00084	657322.FPR_21550	6.63e-122	348.0	2EJZS@1|root,33DQA@2|Bacteria,1VHWG@1239|Firmicutes,24STU@186801|Clostridia,3WMHW@541000|Ruminococcaceae	186801|Clostridia	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
NFPJHIIC_00085	748224.HMPREF9436_00897	4.03e-162	459.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
NFPJHIIC_00086	657322.FPR_21530	1.63e-235	649.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3WGF8@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NFPJHIIC_00087	657322.FPR_21520	5.2e-132	374.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NFPJHIIC_00088	657322.FPR_21510	6.48e-99	287.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WK0P@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
NFPJHIIC_00089	657322.FPR_21500	0.0	1325.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NFPJHIIC_00090	657322.FPR_21490	1.52e-68	211.0	COG3027@1|root,COG3027@2|Bacteria,1VGM3@1239|Firmicutes,24T2P@186801|Clostridia,3WM0A@541000|Ruminococcaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
NFPJHIIC_00091	657322.FPR_25510	2.66e-175	489.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3WNW2@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NFPJHIIC_00092	411471.SUBVAR_04806	2.34e-207	582.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0N@1239|Firmicutes,24GNF@186801|Clostridia,3WNMP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFPJHIIC_00093	397288.C806_03281	2.99e-154	452.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,27J9K@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	effD	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00094	397288.C806_03275	3.98e-150	430.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.30	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00088,M00572	R01361,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NFPJHIIC_00095	1226325.HMPREF1548_04369	6.49e-18	84.0	COG1309@1|root,COG1309@2|Bacteria,1V7J5@1239|Firmicutes,24JZZ@186801|Clostridia,36KF2@31979|Clostridiaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00096	657322.FPR_25480	1.49e-310	846.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WHUT@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
NFPJHIIC_00097	657322.FPR_25470	0.0	920.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,24EDK@186801|Clostridia,3WNX0@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
NFPJHIIC_00098	657322.FPR_25460	0.0	1439.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WNIG@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFPJHIIC_00099	657322.FPR_25450	0.0	1218.0	COG3507@1|root,COG3507@2|Bacteria,1TQBJ@1239|Firmicutes,24CFJ@186801|Clostridia,3WNRJ@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
NFPJHIIC_00100	657322.FPR_25440	1.46e-202	560.0	COG1082@1|root,COG1082@2|Bacteria,1TRMY@1239|Firmicutes,24CP4@186801|Clostridia,3WP0G@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFPJHIIC_00101	657322.FPR_25430	0.0	1750.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,3WHJG@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-rhamnosidase N-terminal domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
NFPJHIIC_00102	657322.FPR_25420	5.82e-272	745.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia,3WIIJ@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFPJHIIC_00103	657322.FPR_25410	0.0	890.0	COG5434@1|root,COG5434@2|Bacteria,1V4PZ@1239|Firmicutes,24CQH@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
NFPJHIIC_00104	657322.FPR_25400	7.94e-290	794.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFPJHIIC_00105	657322.FPR_25390	2.83e-110	318.0	COG3090@1|root,COG3090@2|Bacteria,1TUNV@1239|Firmicutes,25N0I@186801|Clostridia,3WQH9@541000|Ruminococcaceae	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFPJHIIC_00106	657322.FPR_25380	1.92e-240	661.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,3WRTV@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFPJHIIC_00107	1203606.HMPREF1526_02993	1.97e-84	263.0	COG2140@1|root,COG2207@1|root,COG2140@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,24ISI@186801|Clostridia,36VKV@31979|Clostridiaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFPJHIIC_00109	718252.FP2_29970	1.28e-166	493.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFPJHIIC_00110	657322.FPR_31360	0.0	1276.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFPJHIIC_00111	657322.FPR_31370	1.16e-118	339.0	COG1994@1|root,COG1994@2|Bacteria,1VK5P@1239|Firmicutes,24UYF@186801|Clostridia	186801|Clostridia	S	Peptidase M50	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
NFPJHIIC_00112	657322.FPR_31380	6.14e-122	348.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24RH8@186801|Clostridia,3WPUG@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NFPJHIIC_00113	657322.FPR_31390	0.0	1524.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NFPJHIIC_00114	657322.FPR_31400	9.19e-76	226.0	COG1555@1|root,COG1555@2|Bacteria,1UQNT@1239|Firmicutes,258F9@186801|Clostridia,3WMJR@541000|Ruminococcaceae	186801|Clostridia	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
NFPJHIIC_00115	657322.FPR_31410	5.2e-188	523.0	COG0561@1|root,COG0561@2|Bacteria,1V8Z5@1239|Firmicutes	1239|Firmicutes	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFPJHIIC_00116	657322.FPR_31420	3.01e-225	620.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFPJHIIC_00117	657322.FPR_31430	1.94e-99	290.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WJWG@541000|Ruminococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NFPJHIIC_00118	748224.HMPREF9436_01479	0.0	1881.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
NFPJHIIC_00119	657322.FPR_31450	2.14e-136	393.0	COG3599@1|root,COG3599@2|Bacteria,1VGCY@1239|Firmicutes,24TVY@186801|Clostridia,3WM0J@541000|Ruminococcaceae	186801|Clostridia	D	DivIVA domain protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
NFPJHIIC_00120	657322.FPR_31460	4.88e-196	543.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
NFPJHIIC_00121	657322.FPR_31470	3.29e-104	301.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3WJJD@541000|Ruminococcaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
NFPJHIIC_00122	657322.FPR_31480	9.69e-309	842.0	COG0845@1|root,COG0845@2|Bacteria,1V9GB@1239|Firmicutes,24HX2@186801|Clostridia,3WJMC@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00123	748224.HMPREF9436_01474	4.03e-178	501.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NFPJHIIC_00124	657322.FPR_31500	0.0	1190.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NFPJHIIC_00125	657322.FPR_31510	0.0	1700.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NFPJHIIC_00126	657322.FPR_31520	1.79e-92	270.0	COG3679@1|root,COG3679@2|Bacteria,1VDFJ@1239|Firmicutes,24MY6@186801|Clostridia,3WJJP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NFPJHIIC_00127	748224.HMPREF9436_01419	2.73e-212	593.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
NFPJHIIC_00128	657322.FPR_13020	1.17e-220	608.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,24A7U@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFPJHIIC_00130	411483.FAEPRAA2165_01076	1.19e-99	291.0	2DMMK@1|root,32SFZ@2|Bacteria,1VARW@1239|Firmicutes,24NN3@186801|Clostridia,3WPMY@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00131	657322.FPR_12990	4.38e-303	827.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NFPJHIIC_00132	657322.FPR_12980	1.5e-101	296.0	COG4720@1|root,COG4720@2|Bacteria,1VBF6@1239|Firmicutes,25FRN@186801|Clostridia,3WSQ6@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NFPJHIIC_00133	657322.FPR_12970	0.0	1155.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,3WHMS@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase family M3	pz-A	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
NFPJHIIC_00136	657322.FPR_12950	2.29e-190	530.0	2DMNS@1|root,32SQE@2|Bacteria,1VDD5@1239|Firmicutes,24Q5C@186801|Clostridia,3WQDG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00137	657322.FPR_12940	1.85e-158	446.0	2E77V@1|root,32VJN@2|Bacteria,1VA37@1239|Firmicutes,24P5M@186801|Clostridia,3WKQS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00138	657322.FPR_12930	1.15e-120	344.0	2C8MG@1|root,32X91@2|Bacteria,1VD66@1239|Firmicutes,24NA1@186801|Clostridia,3WKPS@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00139	657322.FPR_12920	1.64e-120	344.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,3WKHH@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFPJHIIC_00140	748224.HMPREF9436_02194	1.82e-183	515.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NFPJHIIC_00141	657322.FPR_12890	7.59e-193	537.0	COG1149@1|root,COG2878@1|root,COG1149@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
NFPJHIIC_00142	657322.FPR_12880	3.97e-137	389.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3WIFG@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NFPJHIIC_00143	657322.FPR_12870	1.75e-150	424.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3WHAI@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NFPJHIIC_00144	657322.FPR_12860	1.54e-119	342.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3WKJX@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
NFPJHIIC_00145	657322.FPR_12850	6.23e-218	602.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3WGC0@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NFPJHIIC_00146	748224.HMPREF9436_02161	9.26e-309	842.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,MTHFR_C,RnfC_N,SLBB
NFPJHIIC_00149	657322.FPR_12810	5.69e-137	386.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3WICX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00150	657322.FPR_12800	0.0	1268.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WNVD@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NFPJHIIC_00151	657322.FPR_12790	6.58e-67	208.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFPJHIIC_00152	748224.HMPREF9436_03012	4.07e-266	734.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia,3WHRP@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
NFPJHIIC_00153	657322.FPR_21090	7.39e-187	520.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia	186801|Clostridia	M	serine-type D-Ala-D-Ala carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
NFPJHIIC_00154	657322.FPR_21080	1.24e-278	763.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NFPJHIIC_00155	657322.FPR_21070	3.74e-210	581.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,3WH2P@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
NFPJHIIC_00156	657322.FPR_21060	5.43e-295	805.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
NFPJHIIC_00157	748224.HMPREF9436_03007	7.82e-87	256.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3WK80@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
NFPJHIIC_00158	657322.FPR_21040	0.0	1621.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,3WHIF@541000|Ruminococcaceae	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NFPJHIIC_00160	657322.FPR_21020	0.0	1092.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3WGTX@541000|Ruminococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NFPJHIIC_00162	657322.FPR_20990	9.78e-151	424.0	COG3764@1|root,COG3764@2|Bacteria,1VBCZ@1239|Firmicutes,24M77@186801|Clostridia,3WK15@541000|Ruminococcaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFPJHIIC_00163	657322.FPR_20980	6.49e-222	613.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NFPJHIIC_00164	748224.HMPREF9436_02936	6.88e-73	223.0	COG1846@1|root,COG1846@2|Bacteria,1UQ0B@1239|Firmicutes,257MR@186801|Clostridia,3WMF0@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
NFPJHIIC_00165	657322.FPR_20960	0.0	1392.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGF7@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFPJHIIC_00166	657322.FPR_20950	0.0	1118.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFPJHIIC_00167	657322.FPR_20940	1.43e-222	613.0	COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,24G8Z@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFPJHIIC_00168	657322.FPR_29320	2.2e-158	460.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
NFPJHIIC_00169	657322.FPR_29310	1.78e-244	674.0	COG2433@1|root,COG2433@2|Bacteria,1UK5K@1239|Firmicutes,25FKU@186801|Clostridia,3WSNW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NFPJHIIC_00170	657322.FPR_29300	3.52e-311	847.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NFPJHIIC_00171	411483.FAEPRAA2165_00771	0.0	973.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NFPJHIIC_00172	657322.FPR_29280	7.62e-171	478.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
NFPJHIIC_00173	657322.FPR_29270	0.0	940.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,3WIHF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
NFPJHIIC_00174	657322.FPR_29260	1.82e-170	476.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,3WH0B@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFPJHIIC_00175	657322.FPR_29250	1.63e-264	728.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
NFPJHIIC_00176	657322.FPR_29240	1.23e-175	492.0	COG0614@1|root,COG4822@1|root,COG0614@2|Bacteria,COG4822@2|Bacteria,1UK9K@1239|Firmicutes,25FRK@186801|Clostridia,3WJHV@541000|Ruminococcaceae	186801|Clostridia	HP	small periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00177	657322.FPR_29230	9.08e-260	713.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NFPJHIIC_00178	657322.FPR_29220	1.63e-218	605.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3WI1U@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NFPJHIIC_00179	657322.FPR_29210	0.0	1229.0	COG1120@1|root,COG1903@1|root,COG1120@2|Bacteria,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3WH1E@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
NFPJHIIC_00180	657322.FPR_29200	1.97e-176	492.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NFPJHIIC_00181	657322.FPR_29190	3.82e-230	634.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WHCR@541000|Ruminococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
NFPJHIIC_00182	657322.FPR_29180	4.65e-181	504.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3WHE5@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-3B	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NFPJHIIC_00183	657322.FPR_29170	2.98e-163	458.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,3WJ9U@541000|Ruminococcaceae	186801|Clostridia	H	reductase	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,4.99.1.4	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05150,R05812	RC01012,RC01034,RC01280	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiJ,NAD_binding_7
NFPJHIIC_00184	657322.FPR_29160	2.76e-270	741.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3WGQY@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
NFPJHIIC_00185	657322.FPR_30410	4.06e-35	120.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,256ZU@186801|Clostridia,3WR05@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NFPJHIIC_00186	748224.HMPREF9436_01551	3.29e-208	585.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WGCP@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NFPJHIIC_00187	748224.HMPREF9436_01550	1.4e-166	469.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,3WG7R@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NFPJHIIC_00188	657322.FPR_30380	9.59e-101	292.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3WK9U@541000|Ruminococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NFPJHIIC_00189	657322.FPR_30370	4.91e-78	233.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3WKSG@541000|Ruminococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
NFPJHIIC_00190	657322.FPR_30360	1.84e-120	347.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
NFPJHIIC_00191	748224.HMPREF9436_01545	4.16e-61	194.0	2E6BB@1|root,32FH3@2|Bacteria,1V7J4@1239|Firmicutes,24J8Z@186801|Clostridia,3WKIY@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
NFPJHIIC_00193	657322.FPR_30330	1.92e-240	662.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WJA7@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AE (spore_III_AE)	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
NFPJHIIC_00195	657322.FPR_30310	1.78e-30	108.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NFPJHIIC_00197	748224.HMPREF9436_01539	2.4e-113	336.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
NFPJHIIC_00198	748224.HMPREF9436_01538	0.0	1212.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NFPJHIIC_00199	657322.FPR_30270	0.0	972.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHVR@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
NFPJHIIC_00200	657322.FPR_30250	1.35e-149	421.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
NFPJHIIC_00201	657322.FPR_30240	6.76e-213	587.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
NFPJHIIC_00202	657322.FPR_30230	0.0	1165.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NFPJHIIC_00203	657322.FPR_30220	1.45e-181	504.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NFPJHIIC_00204	657322.FPR_30210	1.17e-247	680.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NFPJHIIC_00205	657322.FPR_30200	1.07e-299	820.0	COG0144@1|root,COG0144@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
NFPJHIIC_00206	657322.FPR_30190	1.08e-153	435.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NFPJHIIC_00207	657322.FPR_16680	6.74e-120	359.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NFPJHIIC_00208	657322.FPR_16670	4.05e-135	383.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3WIGD@541000|Ruminococcaceae	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NFPJHIIC_00209	657322.FPR_16660	4.05e-208	575.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3WHU4@541000|Ruminococcaceae	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
NFPJHIIC_00210	657322.FPR_16650	1.32e-57	181.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NFPJHIIC_00211	411483.FAEPRAA2165_01008	2.94e-113	325.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WIH7@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NFPJHIIC_00212	657322.FPR_16630	1.68e-157	442.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NFPJHIIC_00213	657322.FPR_16620	3.98e-92	270.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NFPJHIIC_00214	657322.FPR_16610	8.66e-130	368.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3WJ0G@541000|Ruminococcaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NFPJHIIC_00215	657322.FPR_16600	4.49e-46	149.0	COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,24UI4@186801|Clostridia,3WM9N@541000|Ruminococcaceae	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NFPJHIIC_00216	411483.FAEPRAA2165_01014	1.26e-28	102.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3WKQN@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
NFPJHIIC_00217	657322.FPR_16580	4.39e-268	733.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NFPJHIIC_00218	657322.FPR_16570	9.85e-197	545.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3WGBW@541000|Ruminococcaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NFPJHIIC_00219	748224.HMPREF9436_02467	3.78e-96	281.0	COG4506@1|root,COG4506@2|Bacteria,1VCRX@1239|Firmicutes,24NFZ@186801|Clostridia,3WK9H@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1934
NFPJHIIC_00220	657322.FPR_16550	0.0	1189.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3WHFX@541000|Ruminococcaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NFPJHIIC_00221	657322.FPR_16540	2.76e-247	678.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WGDN@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NFPJHIIC_00222	657322.FPR_16530	3.62e-137	388.0	COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia,3WGMJ@541000|Ruminococcaceae	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase HD sub domain	yfbR	-	3.1.3.89	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	-	R01569,R01664,R01968,R02088,R02102,R10776	RC00017	ko00000,ko00001,ko01000	-	-	-	HD_2,HD_3
NFPJHIIC_00223	657322.FPR_16520	0.0	1609.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24C9R@186801|Clostridia,3WH8M@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NFPJHIIC_00224	657322.FPR_16510	6.45e-230	637.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3WIFV@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NFPJHIIC_00225	657322.FPR_16500	2.57e-203	565.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NFPJHIIC_00226	657322.FPR_16490	5.39e-184	513.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NFPJHIIC_00227	657322.FPR_16480	8.36e-123	352.0	COG1802@1|root,COG1802@2|Bacteria,1V5DF@1239|Firmicutes,24HJU@186801|Clostridia,3WRUX@541000|Ruminococcaceae	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFPJHIIC_00228	657322.FPR_20770	1.18e-226	627.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3WJKQ@541000|Ruminococcaceae	186801|Clostridia	S	basic membrane	tmpC	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NFPJHIIC_00229	748224.HMPREF9436_00937	0.0	944.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NFPJHIIC_00230	657322.FPR_20790	4.58e-253	697.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHM5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NFPJHIIC_00231	657322.FPR_20800	7.42e-203	563.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WHCN@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NFPJHIIC_00232	657322.FPR_20810	2.15e-147	417.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,3WJVW@541000|Ruminococcaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
NFPJHIIC_00233	657322.FPR_20820	2.06e-161	454.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,3WI2V@541000|Ruminococcaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
NFPJHIIC_00234	657322.FPR_20830	2.94e-186	516.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3WK04@541000|Ruminococcaceae	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NFPJHIIC_00235	657322.FPR_20840	1.48e-138	397.0	2BCB7@1|root,325WH@2|Bacteria,1VU5S@1239|Firmicutes	657322.FPR_20840|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00236	657322.FPR_20850	1.43e-200	557.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WIHH@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NFPJHIIC_00237	657322.FPR_20860	4.86e-237	653.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WITY@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NFPJHIIC_00238	657322.FPR_20870	1.53e-241	663.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFPJHIIC_00239	657322.FPR_20880	2.35e-244	670.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFPJHIIC_00240	657322.FPR_20890	0.0	918.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3WHJ3@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type oligopeptide transport system periplasmic component	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
NFPJHIIC_00242	657322.FPR_20910	0.0	1145.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NFPJHIIC_00243	657322.FPR_20920	3.77e-217	599.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3WH7J@541000|Ruminococcaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NFPJHIIC_00244	657322.FPR_20930	1.75e-204	581.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TT1Q@1239|Firmicutes,249N4@186801|Clostridia,3WHHS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
NFPJHIIC_00245	657322.FPR_01900	6.21e-266	727.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
NFPJHIIC_00246	657322.FPR_01910	2.31e-95	278.0	COG3682@1|root,COG3682@2|Bacteria,1VQ59@1239|Firmicutes,24WQW@186801|Clostridia,3WMD3@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NFPJHIIC_00247	657322.FPR_01920	0.0	905.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WGKI@541000|Ruminococcaceae	186801|Clostridia	C	citrate synthase	gltA2	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NFPJHIIC_00248	657322.FPR_01930	8.81e-98	285.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00249	748224.HMPREF9436_01806	1.98e-213	596.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
NFPJHIIC_00250	657322.FPR_01950	0.0	1381.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
NFPJHIIC_00251	657322.FPR_01960	0.0	1607.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NFPJHIIC_00252	657322.FPR_01970	2.5e-162	454.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3WGED@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location Cytoplasmic, score	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NFPJHIIC_00253	657322.FPR_01980	8.11e-152	426.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3WHYJ@541000|Ruminococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
NFPJHIIC_00254	657322.FPR_01990	3.34e-145	409.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,3WNBN@541000|Ruminococcaceae	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
NFPJHIIC_00255	657322.FPR_02000	0.0	903.0	COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia,3WJ7Y@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10192	ko02010,map02010	M00202,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
NFPJHIIC_00256	657322.FPR_02010	3.49e-219	605.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,248DR@186801|Clostridia,3WISE@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K02025,ko:K10193	ko02010,map02010	M00202,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	-	BPD_transp_1
NFPJHIIC_00257	657322.FPR_02020	4.01e-210	580.0	COG0395@1|root,COG0395@2|Bacteria,1TSYB@1239|Firmicutes,24AKM@186801|Clostridia,3WIYF@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10194	ko02010,map02010	M00202	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.11	-	-	BPD_transp_1
NFPJHIIC_00258	657322.FPR_02030	1.14e-172	484.0	COG2169@1|root,COG2169@2|Bacteria,1UK9J@1239|Firmicutes,25BJT@186801|Clostridia,3WKTP@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NFPJHIIC_00259	748224.HMPREF9436_01368	1.91e-288	806.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
NFPJHIIC_00260	657322.FPR_19720	1.9e-104	302.0	COG0737@1|root,COG0737@2|Bacteria,1VC1M@1239|Firmicutes,24PE1@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	SLH
NFPJHIIC_00261	657322.FPR_19710	0.0	867.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3WH7R@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NFPJHIIC_00262	657322.FPR_19700	0.0	951.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia	186801|Clostridia	E	amino acid	NPD5_3681	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NFPJHIIC_00263	657322.FPR_19690	7.72e-156	437.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3WH3Z@541000|Ruminococcaceae	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFPJHIIC_00264	657322.FPR_19680	3.71e-110	316.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NFPJHIIC_00265	748224.HMPREF9436_01363	1.48e-63	196.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia,3WK16@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
NFPJHIIC_00266	657322.FPR_19660	1.41e-75	226.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,24Q04@186801|Clostridia,3WM4U@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00267	657322.FPR_19650	7.81e-89	260.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WKPB@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NFPJHIIC_00268	657322.FPR_19640	1.35e-191	531.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3WJFW@541000|Ruminococcaceae	186801|Clostridia	S	HAD hydrolase, family IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFPJHIIC_00269	657322.FPR_19630	1.28e-193	538.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3WSC5@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NFPJHIIC_00270	1304872.JAGC01000009_gene297	6.57e-06	55.1	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42RKJ@68525|delta/epsilon subdivisions,2WNN5@28221|Deltaproteobacteria,2MB03@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFPJHIIC_00273	657322.FPR_19580	0.0	1866.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGE7@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
NFPJHIIC_00274	657322.FPR_19570	3.41e-193	536.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3WGSS@541000|Ruminococcaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
NFPJHIIC_00276	657322.FPR_19560	2.77e-57	198.0	COG1961@1|root,COG1961@2|Bacteria,1TRVQ@1239|Firmicutes,249AZ@186801|Clostridia,3WGI0@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFPJHIIC_00277	657322.FPR_25340	0.0	1175.0	COG4289@1|root,COG4289@2|Bacteria,1TSHI@1239|Firmicutes,24C95@186801|Clostridia,3WNAB@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264
NFPJHIIC_00278	657322.FPR_25330	8.28e-298	810.0	COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,248Z1@186801|Clostridia,3WN7Z@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
NFPJHIIC_00279	657322.FPR_25320	0.0	1254.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WP1V@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFPJHIIC_00280	657322.FPR_25310	2.32e-201	558.0	COG0395@1|root,COG0395@2|Bacteria,1TPIF@1239|Firmicutes,25C5D@186801|Clostridia,3WSB1@541000|Ruminococcaceae	186801|Clostridia	P	Carbohydrate ABC transporter membrane protein 2, CUT1 family	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFPJHIIC_00281	748224.HMPREF9436_01911	8.28e-222	611.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,25C59@186801|Clostridia,3WJAA@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFPJHIIC_00282	657322.FPR_25290	3.18e-299	818.0	COG1653@1|root,COG1653@2|Bacteria,1TQ6X@1239|Firmicutes,24B3P@186801|Clostridia,3WNQA@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-)	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
NFPJHIIC_00283	657322.FPR_25280	0.0	1189.0	COG2972@1|root,COG2972@2|Bacteria,1TQZM@1239|Firmicutes,247ZV@186801|Clostridia,3WN4N@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
NFPJHIIC_00284	657322.FPR_25270	1.46e-299	817.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TPDP@1239|Firmicutes,24A5I@186801|Clostridia,3WK9T@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFPJHIIC_00285	657322.FPR_25260	0.0	1239.0	COG4225@1|root,COG4225@2|Bacteria,1UXGZ@1239|Firmicutes,25D7M@186801|Clostridia	186801|Clostridia	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
NFPJHIIC_00286	657322.FPR_25250	2.15e-195	541.0	2DBRG@1|root,2ZAKM@2|Bacteria,1UQ8F@1239|Firmicutes,24CHJ@186801|Clostridia,3WN9M@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00287	748224.HMPREF9436_01919	0.0	872.0	2DJT4@1|root,32UDS@2|Bacteria,1VDA1@1239|Firmicutes,24SD3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00289	657322.FPR_17350	0.0	1191.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,PrpR_N,Sigma54_activ_2,Sigma54_activat
NFPJHIIC_00290	657322.FPR_17360	2.7e-296	808.0	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,25CF7@186801|Clostridia	186801|Clostridia	S	Putative sugar-binding N-terminal domain	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
NFPJHIIC_00291	657322.FPR_17370	2.21e-304	827.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,1UZJR@1239|Firmicutes,24CZ3@186801|Clostridia,3WP79@541000|Ruminococcaceae	186801|Clostridia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
NFPJHIIC_00292	657322.FPR_17380	1.76e-277	759.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NFPJHIIC_00293	657322.FPR_17390	7.92e-218	601.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,3WGIU@541000|Ruminococcaceae	186801|Clostridia	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NFPJHIIC_00294	657322.FPR_17400	1.85e-265	726.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,3WIJ8@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
NFPJHIIC_00295	657322.FPR_17410	1.41e-284	780.0	COG1055@1|root,COG1055@2|Bacteria	2|Bacteria	P	arsenite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
NFPJHIIC_00296	657322.FPR_17420	1.58e-81	241.0	COG0800@1|root,COG0800@2|Bacteria,1V5NJ@1239|Firmicutes,24NKP@186801|Clostridia	186801|Clostridia	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00297	657322.FPR_17430	9.77e-197	549.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NFPJHIIC_00298	657322.FPR_17440	9.79e-199	553.0	COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,24AKZ@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFPJHIIC_00299	657322.FPR_17450	1.24e-204	567.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia,3WNP8@541000|Ruminococcaceae	186801|Clostridia	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
NFPJHIIC_00300	657322.FPR_17460	0.0	913.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3WG8J@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NFPJHIIC_00301	657322.FPR_30580	1.46e-34	119.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3WKMJ@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
NFPJHIIC_00304	657322.FPR_30610	0.0	865.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3WG8G@541000|Ruminococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
NFPJHIIC_00305	657322.FPR_30620	1.21e-281	770.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WGCI@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NFPJHIIC_00306	748224.HMPREF9436_01574	2.26e-133	385.0	COG0860@1|root,COG0860@2|Bacteria,1V4XQ@1239|Firmicutes,24KYC@186801|Clostridia,3WRIQ@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
NFPJHIIC_00307	657322.FPR_30640	0.0	1410.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3WGD7@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
NFPJHIIC_00308	657322.FPR_30650	6.35e-176	490.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3WJ6A@541000|Ruminococcaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NFPJHIIC_00309	411483.FAEPRAA2165_02333	1.09e-199	555.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
NFPJHIIC_00310	657322.FPR_30670	1.95e-114	328.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
NFPJHIIC_00311	748224.HMPREF9436_01579	6.24e-212	588.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3WHAN@541000|Ruminococcaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
NFPJHIIC_00312	657322.FPR_30700	1.17e-67	205.0	COG1695@1|root,COG1695@2|Bacteria,1V9XX@1239|Firmicutes,24RE5@186801|Clostridia,3WK2V@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NFPJHIIC_00313	657322.FPR_30710	9.97e-119	339.0	2DN4N@1|root,32UIA@2|Bacteria,1VA2T@1239|Firmicutes,24JJM@186801|Clostridia,3WJZR@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
NFPJHIIC_00315	657322.FPR_30730	2.69e-188	523.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
NFPJHIIC_00316	657322.FPR_30740	3.07e-241	664.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,3WJ0T@541000|Ruminococcaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NFPJHIIC_00317	657322.FPR_30750	2.5e-51	161.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3WMI7@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NFPJHIIC_00318	748224.HMPREF9436_01585	1.52e-33	125.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NFPJHIIC_00319	657322.FPR_15880	3.34e-286	782.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
NFPJHIIC_00320	657322.FPR_15870	8.49e-79	234.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NFPJHIIC_00321	657322.FPR_15860	3.88e-283	774.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WH1M@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
NFPJHIIC_00322	748224.HMPREF9436_01317	7.67e-84	261.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,249DU@186801|Clostridia,3WKV2@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
NFPJHIIC_00323	657322.FPR_15830	3.59e-163	458.0	295NP@1|root,2ZT02@2|Bacteria,1W38K@1239|Firmicutes,2569B@186801|Clostridia,3WQQ1@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00324	657322.FPR_15820	3.91e-251	692.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NFPJHIIC_00325	657322.FPR_15810	1.28e-137	390.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3WKZM@541000|Ruminococcaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NFPJHIIC_00326	657322.FPR_15800	5.18e-114	327.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,3WJEI@541000|Ruminococcaceae	186801|Clostridia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NFPJHIIC_00327	657322.FPR_15790	3.63e-220	606.0	COG0561@1|root,COG0561@2|Bacteria,1TRXT@1239|Firmicutes,24SES@186801|Clostridia,3WRI6@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFPJHIIC_00328	657322.FPR_15780	1.1e-199	554.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
NFPJHIIC_00329	657322.FPR_15770	3.84e-185	514.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NFPJHIIC_00330	657322.FPR_15760	1.48e-272	744.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3WGZU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NFPJHIIC_00331	657322.FPR_15750	4.87e-300	820.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NFPJHIIC_00332	657322.FPR_15740	1.13e-221	611.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3WGNP@541000|Ruminococcaceae	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NFPJHIIC_00334	748224.HMPREF9436_02894	7.79e-99	294.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NFPJHIIC_00336	657322.FPR_06340	7.47e-162	457.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NFPJHIIC_00337	657322.FPR_06350	1.66e-131	373.0	COG0778@1|root,COG0778@2|Bacteria,1V3VK@1239|Firmicutes,25BI4@186801|Clostridia,3WM21@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NFPJHIIC_00339	657322.FPR_06370	4.33e-91	268.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia,3WM0F@541000|Ruminococcaceae	186801|Clostridia	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
NFPJHIIC_00340	657322.FPR_06380	1.74e-180	503.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3WJWQ@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
NFPJHIIC_00341	657322.FPR_06390	1.58e-192	537.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3WIW1@541000|Ruminococcaceae	186801|Clostridia	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
NFPJHIIC_00342	411483.FAEPRAA2165_03034	4.93e-208	579.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3WGFP@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
NFPJHIIC_00343	657322.FPR_06410	2.37e-142	403.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3WIUE@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
NFPJHIIC_00344	657322.FPR_06420	1.96e-315	858.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NFPJHIIC_00345	657322.FPR_06430	2.71e-233	640.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	AA_kinase,HTS
NFPJHIIC_00346	657322.FPR_06440	1.73e-214	591.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,3WHUR@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NFPJHIIC_00347	657322.FPR_06450	2.18e-127	361.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3WIDH@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NFPJHIIC_00348	748224.HMPREF9436_02320	5.26e-162	460.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3WGAX@541000|Ruminococcaceae	186801|Clostridia	H	Pyridoxal kinase	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
NFPJHIIC_00351	657322.FPR_06490	5.62e-217	608.0	COG1145@1|root,COG2221@1|root,COG4624@1|root,COG1145@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3WGZI@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
NFPJHIIC_00352	718252.FP2_08390	2.35e-37	129.0	COG0745@1|root,COG0745@2|Bacteria,1VH87@1239|Firmicutes,24T6J@186801|Clostridia,3WQ3D@541000|Ruminococcaceae	186801|Clostridia	KT	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NFPJHIIC_00354	411483.FAEPRAA2165_00913	2.39e-78	233.0	COG1476@1|root,COG1476@2|Bacteria,1UK9D@1239|Firmicutes,25FRC@186801|Clostridia,3WMKB@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFPJHIIC_00355	411483.FAEPRAA2165_00916	4.98e-112	322.0	COG1595@1|root,COG1595@2|Bacteria,1V4NR@1239|Firmicutes,24RRU@186801|Clostridia,3WKQW@541000|Ruminococcaceae	186801|Clostridia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NFPJHIIC_00357	411483.FAEPRAA2165_00918	1.5e-157	442.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes	1239|Firmicutes	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NFPJHIIC_00358	411483.FAEPRAA2165_00919	3.19e-200	553.0	COG1475@1|root,COG1475@2|Bacteria,1UYXH@1239|Firmicutes,24B4U@186801|Clostridia,3WI4E@541000|Ruminococcaceae	186801|Clostridia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00359	411483.FAEPRAA2165_00920	4.22e-41	135.0	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes,24URE@186801|Clostridia,3WM8T@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NFPJHIIC_00360	748224.HMPREF9436_01074	2.53e-246	677.0	COG4974@1|root,COG4974@2|Bacteria,1UK9E@1239|Firmicutes,25FRD@186801|Clostridia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NFPJHIIC_00362	657322.FPR_20010	7.76e-189	524.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3WKFF@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
NFPJHIIC_00363	657322.FPR_20000	0.0	1295.0	COG0737@1|root,COG0737@2|Bacteria,1UK63@1239|Firmicutes,25FMA@186801|Clostridia	186801|Clostridia	F	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
NFPJHIIC_00364	657322.FPR_19990	1.27e-273	750.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3WGNK@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFPJHIIC_00365	657322.FPR_19980	4.29e-174	486.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFPJHIIC_00366	657322.FPR_19970	0.0	1105.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,3WHII@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NFPJHIIC_00367	657322.FPR_19960	7.32e-91	266.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
NFPJHIIC_00368	657322.FPR_19950	6.52e-91	283.0	COG1053@1|root,COG4939@1|root,COG1053@2|Bacteria,COG4939@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind
NFPJHIIC_00369	657322.FPR_05370	0.0	1508.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,3WQA7@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	M00309,M00541	R08571,R10961	RC00242,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
NFPJHIIC_00370	657322.FPR_05380	4.48e-145	409.0	COG0437@1|root,COG0437@2|Bacteria,1TT1R@1239|Firmicutes,24FGW@186801|Clostridia,3WMM7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
NFPJHIIC_00372	657322.FPR_05400	4.13e-180	501.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,3WPB6@541000|Ruminococcaceae	186801|Clostridia	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
NFPJHIIC_00373	657322.FPR_05410	0.0	1136.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3WGIC@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
NFPJHIIC_00374	657322.FPR_05420	0.0	872.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFPJHIIC_00375	657322.FPR_05430	0.0	980.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3WHJQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
NFPJHIIC_00376	657322.FPR_05440	0.0	1208.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3WHCI@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NFPJHIIC_00377	657322.FPR_05450	4.67e-204	566.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3WH8H@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFPJHIIC_00378	657322.FPR_05460	1.07e-59	189.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3WIVJ@541000|Ruminococcaceae	186801|Clostridia	K	COG COG1349 Transcriptional regulators of sugar metabolism	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NFPJHIIC_00379	1123399.AQVE01000007_gene1099	4.2e-11	71.6	COG1835@1|root,COG1835@2|Bacteria,1N70C@1224|Proteobacteria,1SE0F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFPJHIIC_00380	657322.FPR_21840	2.52e-237	652.0	COG1597@1|root,COG1597@2|Bacteria,1V1DP@1239|Firmicutes,25CN2@186801|Clostridia,3WIT5@541000|Ruminococcaceae	186801|Clostridia	I	Lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NFPJHIIC_00381	657322.FPR_21830	0.0	1450.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WGYI@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
NFPJHIIC_00382	657322.FPR_21820	8.28e-172	483.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,25CUP@186801|Clostridia,3WJ66@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
NFPJHIIC_00383	657322.FPR_21810	1.4e-259	711.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00384	657322.FPR_21800	2.11e-283	780.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WHZY@541000|Ruminococcaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
NFPJHIIC_00385	657322.FPR_21780	0.0	933.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WGU8@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NFPJHIIC_00386	657322.FPR_21770	0.0	876.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WGP4@541000|Ruminococcaceae	186801|Clostridia	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NFPJHIIC_00387	657322.FPR_21760	3.95e-309	843.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WGW3@541000|Ruminococcaceae	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
NFPJHIIC_00388	657322.FPR_21750	4.56e-121	353.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3WI1M@541000|Ruminococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
NFPJHIIC_00390	657322.FPR_27930	1.25e-85	252.0	arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,24KJW@186801|Clostridia,3WKZS@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_1
NFPJHIIC_00391	657322.FPR_27940	0.0	1401.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,3WJ3P@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase class C	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
NFPJHIIC_00392	657322.FPR_27950	5.38e-271	742.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia,3WHGF@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFPJHIIC_00393	657322.FPR_27960	2e-242	668.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WJT0@541000|Ruminococcaceae	186801|Clostridia	M	mechanosensitive ion channel	-	-	-	ko:K16052,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3,1.A.23.4	-	-	MS_channel
NFPJHIIC_00394	657322.FPR_27970	9.13e-133	377.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NFPJHIIC_00395	657322.FPR_27980	0.0	886.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WIF4@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00396	657322.FPR_27990	5.57e-220	607.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WGWB@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 4	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NFPJHIIC_00397	657322.FPR_28000	3.54e-196	545.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NFPJHIIC_00398	657322.FPR_28010	3.31e-125	359.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
NFPJHIIC_00399	657322.FPR_28020	5.7e-118	339.0	COG0212@1|root,COG0212@2|Bacteria	2|Bacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
NFPJHIIC_00400	657322.FPR_28030	1.78e-303	827.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WGJK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
NFPJHIIC_00401	657322.FPR_28040	9.51e-119	339.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,3WJWD@541000|Ruminococcaceae	186801|Clostridia	H	cob(I)yrinic acid a,c-diamide adenosyltransferase	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
NFPJHIIC_00402	748224.HMPREF9436_01534	3.48e-36	136.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3WGEC@541000|Ruminococcaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
NFPJHIIC_00403	657322.FPR_27660	2.54e-211	592.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3WPUP@541000|Ruminococcaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NFPJHIIC_00404	657322.FPR_27670	0.0	1382.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WI09@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NFPJHIIC_00405	657322.FPR_27680	0.0	1509.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3WGUK@541000|Ruminococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
NFPJHIIC_00406	657322.FPR_27690	3.18e-106	306.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NFPJHIIC_00407	657322.FPR_27700	1.47e-150	422.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3WHAR@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NFPJHIIC_00408	657322.FPR_27710	0.0	989.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFPJHIIC_00409	657322.FPR_27720	8.96e-223	614.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
NFPJHIIC_00410	657322.FPR_27730	7.52e-72	218.0	2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
NFPJHIIC_00411	748224.HMPREF9436_00960	9.6e-120	347.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,3WHY1@541000|Ruminococcaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
NFPJHIIC_00412	657322.FPR_27750	7.71e-52	164.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3WKJ9@541000|Ruminococcaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NFPJHIIC_00413	657322.FPR_27760	2.34e-47	152.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3WKNC@541000|Ruminococcaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
NFPJHIIC_00414	428125.CLOLEP_03271	1.62e-08	54.7	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
NFPJHIIC_00415	657322.FPR_27780	5.35e-91	268.0	291HZ@1|root,2ZP4H@2|Bacteria,1W64S@1239|Firmicutes,256EU@186801|Clostridia,3WQKY@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00416	657322.FPR_27790	4.49e-61	188.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24WD9@186801|Clostridia,3WMHC@541000|Ruminococcaceae	186801|Clostridia	D	septum formation initiator	-	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
NFPJHIIC_00417	748224.HMPREF9436_00966	9.5e-92	272.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,3WJUX@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
NFPJHIIC_00418	657322.FPR_10610	6.66e-113	323.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,3WIYS@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
NFPJHIIC_00419	657322.FPR_10620	2.7e-295	806.0	COG0169@1|root,COG0703@1|root,COG0169@2|Bacteria,COG0703@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
NFPJHIIC_00420	657322.FPR_10630	9.48e-262	718.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NFPJHIIC_00421	657322.FPR_10640	4.42e-248	681.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NFPJHIIC_00422	657322.FPR_10650	6.01e-246	676.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NFPJHIIC_00424	657322.FPR_10670	1.34e-182	507.0	2DJT4@1|root,32UDS@2|Bacteria,1VDA1@1239|Firmicutes,24SD3@186801|Clostridia,3WK3G@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00425	657322.FPR_10680	3.13e-168	470.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WI78@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NFPJHIIC_00426	657322.FPR_10690	2.51e-197	547.0	COG5578@1|root,COG5578@2|Bacteria,1UK80@1239|Firmicutes,25FQ0@186801|Clostridia,3WM07@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NFPJHIIC_00427	657322.FPR_10700	0.0	946.0	COG3271@1|root,COG3271@2|Bacteria,1V1IQ@1239|Firmicutes,24FBU@186801|Clostridia,3WNEZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
NFPJHIIC_00428	657322.FPR_10710	3.33e-140	396.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJ2R@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NFPJHIIC_00429	748224.HMPREF9436_01990	1.76e-287	792.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WHF6@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00430	657322.FPR_10730	2.24e-148	419.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia,3WJCX@541000|Ruminococcaceae	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NFPJHIIC_00431	657322.FPR_24130	0.0	906.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WGD4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NFPJHIIC_00432	657322.FPR_24140	3.63e-214	590.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia,3WIE7@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFPJHIIC_00433	657322.FPR_24150	2.38e-310	845.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NFPJHIIC_00436	657322.FPR_24180	0.0	1003.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NFPJHIIC_00437	657322.FPR_24190	4.49e-196	544.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3WHYW@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFPJHIIC_00438	657322.FPR_24200	3.28e-195	542.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3WI3F@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFPJHIIC_00439	657322.FPR_24210	2.78e-308	842.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
NFPJHIIC_00440	657322.FPR_24220	8.7e-233	641.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WH56@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFPJHIIC_00441	657322.FPR_24230	1.08e-139	394.0	COG0125@1|root,COG0125@2|Bacteria,1VI7E@1239|Firmicutes	1239|Firmicutes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,dNK
NFPJHIIC_00442	657322.FPR_06520	1.58e-92	281.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NFPJHIIC_00443	657322.FPR_06530	8.87e-88	258.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3WJSW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00444	657322.FPR_06540	8.53e-120	342.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
NFPJHIIC_00445	411483.FAEPRAA2165_01715	8.45e-38	126.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WKID@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
NFPJHIIC_00446	657322.FPR_06560	0.0	898.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3WGI9@541000|Ruminococcaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
NFPJHIIC_00447	657322.FPR_06570	0.0	893.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NFPJHIIC_00448	657322.FPR_06580	6.84e-147	414.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WJFE@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NFPJHIIC_00449	657322.FPR_06590	4.66e-117	335.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
NFPJHIIC_00450	657322.FPR_06600	3.47e-208	579.0	COG0226@1|root,COG0226@2|Bacteria,1VT8I@1239|Firmicutes,24IAW@186801|Clostridia,3WJDA@541000|Ruminococcaceae	186801|Clostridia	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NFPJHIIC_00452	657322.FPR_06620	2.7e-316	863.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGNN@541000|Ruminococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00453	657322.FPR_06630	5.16e-116	342.0	COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae	186801|Clostridia	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
NFPJHIIC_00454	657322.FPR_06640	3.12e-195	543.0	2EP6H@1|root,33GT7@2|Bacteria,1VPJU@1239|Firmicutes,24X7H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00455	657322.FPR_27910	0.0	1151.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
NFPJHIIC_00457	657322.FPR_27890	0.0	1464.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,3WI0H@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type bacteriocin transporter	-	-	-	ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
NFPJHIIC_00458	657322.FPR_27880	5.3e-104	300.0	COG4978@1|root,COG4978@2|Bacteria,1VFVB@1239|Firmicutes,24P4E@186801|Clostridia,3WQ9A@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00459	657322.FPR_27870	8.44e-244	672.0	COG0845@1|root,COG0845@2|Bacteria,1V5WK@1239|Firmicutes,25D23@186801|Clostridia,3WNT3@541000|Ruminococcaceae	186801|Clostridia	M	HlyD family secretion protein	-	-	-	ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
NFPJHIIC_00460	657322.FPR_27860	0.0	895.0	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3WPAR@541000|Ruminococcaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
NFPJHIIC_00461	657322.FPR_27850	0.0	1174.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
NFPJHIIC_00462	657322.FPR_27840	1.17e-119	343.0	2B6MH@1|root,31ZJY@2|Bacteria,1VA4Q@1239|Firmicutes,24T66@186801|Clostridia,3WRG6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00463	657322.FPR_27830	2.51e-202	560.0	28PVZ@1|root,2ZCGE@2|Bacteria,1UPNZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00464	657322.FPR_27820	1.96e-20	88.6	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3WGN5@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
NFPJHIIC_00465	748224.HMPREF9436_00284	1.31e-31	117.0	COG1475@1|root,COG1475@2|Bacteria,1UV1E@1239|Firmicutes,25E14@186801|Clostridia,3WSHU@541000|Ruminococcaceae	186801|Clostridia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00466	748224.HMPREF9436_00285	7.16e-66	202.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24MWU@186801|Clostridia,3WPMW@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NFPJHIIC_00467	657322.FPR_18680	1.45e-46	149.0	2DQQ0@1|root,3380Y@2|Bacteria,1VF3K@1239|Firmicutes,24S1C@186801|Clostridia	186801|Clostridia	S	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NFPJHIIC_00468	657322.FPR_18670	3.15e-277	758.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247VU@186801|Clostridia,3WIAF@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
NFPJHIIC_00473	657322.FPR_18630	1.76e-164	460.0	COG1396@1|root,COG1396@2|Bacteria,1V2ZX@1239|Firmicutes,24EC9@186801|Clostridia,3WIEA@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NFPJHIIC_00474	657322.FPR_18620	3.26e-65	205.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,zinc_ribbon_2
NFPJHIIC_00475	657322.FPR_18610	2.15e-166	464.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJQD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
NFPJHIIC_00477	657322.FPR_18590	7.08e-251	689.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24E1V@186801|Clostridia,3WPUU@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
NFPJHIIC_00478	657322.FPR_18580	3.37e-273	750.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,3WJFN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
NFPJHIIC_00479	657322.FPR_18570	3.07e-119	340.0	COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,24N5U@186801|Clostridia,3WPZP@541000|Ruminococcaceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
NFPJHIIC_00480	657322.FPR_18560	3.36e-116	340.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3WH26@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NFPJHIIC_00481	657322.FPR_27570	4.49e-112	321.0	COG0454@1|root,COG0456@2|Bacteria,1V1VV@1239|Firmicutes,25CUX@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFPJHIIC_00482	657322.FPR_27580	4.95e-306	834.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,3WM35@541000|Ruminococcaceae	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NFPJHIIC_00483	657322.FPR_27590	0.0	989.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NFPJHIIC_00485	657322.FPR_27610	0.0	1110.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NFPJHIIC_00486	657322.FPR_27620	5.39e-272	745.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
NFPJHIIC_00487	657322.FPR_27630	1.11e-206	572.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
NFPJHIIC_00488	657322.FPR_27640	9.56e-303	827.0	COG4856@1|root,COG4856@2|Bacteria,1V9AC@1239|Firmicutes,25Q6T@186801|Clostridia,3WHS9@541000|Ruminococcaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
NFPJHIIC_00489	657322.FPR_27650	0.0	1033.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
NFPJHIIC_00490	657322.FPR_11690	1.22e-102	299.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WHQ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NFPJHIIC_00491	411483.FAEPRAA2165_02825	1.82e-182	508.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WGEW@541000|Ruminococcaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NFPJHIIC_00492	748224.HMPREF9436_00345	6.09e-53	166.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WK1D@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NFPJHIIC_00493	411483.FAEPRAA2165_02822	7.03e-19	77.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia,3WM8G@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
NFPJHIIC_00494	411483.FAEPRAA2165_02821	5.98e-80	238.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WJ08@541000|Ruminococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NFPJHIIC_00495	411483.FAEPRAA2165_02820	1.78e-88	260.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
NFPJHIIC_00496	411483.FAEPRAA2165_02819	7.23e-135	382.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NFPJHIIC_00497	748224.HMPREF9436_00340	9.41e-223	615.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NFPJHIIC_00498	657322.FPR_11770	2.75e-72	217.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3WIRR@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NFPJHIIC_00499	657322.FPR_11780	4.12e-310	845.0	COG0457@1|root,COG0457@2|Bacteria,1VJFJ@1239|Firmicutes,25AZN@186801|Clostridia,3WS60@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00500	657322.FPR_11790	2.31e-166	465.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,3WGQR@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_00501	657322.FPR_11800	0.0	899.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WGC1@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFPJHIIC_00502	657322.FPR_11810	9.36e-227	624.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3WHQ1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
NFPJHIIC_00503	657322.FPR_11820	1.08e-220	610.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3WGK1@541000|Ruminococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NFPJHIIC_00504	1031711.RSPO_c02830	6.73e-17	87.8	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1K3A8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_00505	748224.HMPREF9436_01521	3.02e-233	643.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NFPJHIIC_00506	657322.FPR_28100	0.0	1002.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
NFPJHIIC_00507	657322.FPR_28110	4.97e-70	211.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WJW1@541000|Ruminococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
NFPJHIIC_00508	657322.FPR_28120	1.03e-138	392.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WHNZ@541000|Ruminococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
NFPJHIIC_00509	657322.FPR_28130	2.48e-111	320.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NFPJHIIC_00511	657322.FPR_28140	3.83e-127	361.0	COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,24IDK@186801|Clostridia,3WIF9@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
NFPJHIIC_00512	411483.FAEPRAA2165_03436	1.91e-145	416.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3WI03@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NFPJHIIC_00513	657322.FPR_28160	0.0	1026.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3WGSV@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NFPJHIIC_00514	657322.FPR_28170	4.69e-220	610.0	28JX7@1|root,2Z9MQ@2|Bacteria,1UZRY@1239|Firmicutes,24AWA@186801|Clostridia,3WPXC@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00515	657322.FPR_28190	4.55e-166	468.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WIDR@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NFPJHIIC_00516	748224.HMPREF9436_03308	3.99e-36	128.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NFPJHIIC_00517	657322.FPR_06310	1.58e-262	718.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WG9H@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NFPJHIIC_00518	657322.FPR_06300	1.81e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WIGV@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NFPJHIIC_00519	657322.FPR_06290	4.2e-303	826.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
NFPJHIIC_00520	657322.FPR_06280	0.0	1101.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3WGCZ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NFPJHIIC_00521	657322.FPR_06260	0.0	1176.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG9V@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NFPJHIIC_00523	657322.FPR_06240	6.31e-310	844.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WGNF@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NFPJHIIC_00524	657322.FPR_06220	4.56e-140	404.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,3WHYR@541000|Ruminococcaceae	186801|Clostridia	S	Major Facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
NFPJHIIC_00525	657322.FPR_28940	0.0	916.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
NFPJHIIC_00526	748224.HMPREF9436_01249	8.65e-96	285.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,3WKAS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
NFPJHIIC_00527	657322.FPR_28920	2.05e-132	377.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WK2C@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NFPJHIIC_00528	657322.FPR_28910	1.26e-244	672.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NFPJHIIC_00529	657322.FPR_28900	6.08e-253	694.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NFPJHIIC_00530	657322.FPR_28890	4.7e-39	129.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3WKJ4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
NFPJHIIC_00531	657322.FPR_28880	6.31e-223	614.0	COG0539@1|root,COG0539@2|Bacteria,1UV93@1239|Firmicutes,249P6@186801|Clostridia,3WH6M@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NFPJHIIC_00532	657322.FPR_28870	2.29e-125	357.0	COG3432@1|root,COG3432@2|Bacteria,1VDQ8@1239|Firmicutes,24R9Q@186801|Clostridia,3WK5T@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4364)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
NFPJHIIC_00533	748224.HMPREF9436_01257	4.62e-312	857.0	COG0370@1|root,COG0370@2|Bacteria,1UK3W@1239|Firmicutes,25FIS@186801|Clostridia,3WSQ3@541000|Ruminococcaceae	186801|Clostridia	P	Stage IV sporulation protein A (spore_IV_A)	spoIVA	-	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
NFPJHIIC_00534	657322.FPR_28850	0.0	882.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3WRU0@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
NFPJHIIC_00535	657322.FPR_28840	2.84e-65	202.0	COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,24874@186801|Clostridia,3WHU2@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
NFPJHIIC_00537	657322.FPR_12490	1.24e-237	654.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
NFPJHIIC_00538	657322.FPR_12500	0.0	1036.0	COG0438@1|root,COG0438@2|Bacteria,1V8AN@1239|Firmicutes,24IIP@186801|Clostridia	186801|Clostridia	M	Glycosyl-transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_5,Glycos_transf_1
NFPJHIIC_00540	657322.FPR_12520	5.57e-270	738.0	COG3594@1|root,COG3594@2|Bacteria,1VEEI@1239|Firmicutes,24UA2@186801|Clostridia,3WR41@541000|Ruminococcaceae	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFPJHIIC_00541	657322.FPR_12530	0.0	991.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,24IFY@186801|Clostridia,3WRIU@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
NFPJHIIC_00542	657322.FPR_12540	7.32e-46	148.0	COG0236@1|root,COG0236@2|Bacteria,1VMEW@1239|Firmicutes,24WDM@186801|Clostridia	186801|Clostridia	IQ	Acyl carrier protein	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFPJHIIC_00543	657322.FPR_12550	9.52e-286	780.0	COG1020@1|root,COG1020@2|Bacteria,1VIM0@1239|Firmicutes,24UTC@186801|Clostridia,3WMHY@541000|Ruminococcaceae	186801|Clostridia	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00544	657322.FPR_12560	1.93e-249	687.0	COG0738@1|root,COG0738@2|Bacteria,1UZWI@1239|Firmicutes,24H3U@186801|Clostridia,3WMSR@541000|Ruminococcaceae	186801|Clostridia	G	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFPJHIIC_00545	657322.FPR_05120	5.97e-132	375.0	COG0681@1|root,COG0681@2|Bacteria,1V542@1239|Firmicutes,24I8N@186801|Clostridia,3WIUD@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
NFPJHIIC_00546	657322.FPR_05110	1.49e-66	208.0	2EMVY@1|root,31QVD@2|Bacteria,1TV7K@1239|Firmicutes,259W4@186801|Clostridia,3WQSZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00548	748224.HMPREF9436_02799	3.03e-47	158.0	COG5263@1|root,COG5263@2|Bacteria,1VFMJ@1239|Firmicutes,24T8X@186801|Clostridia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Flg_new
NFPJHIIC_00550	657322.FPR_05080	5.88e-164	459.0	COG1802@1|root,COG1802@2|Bacteria,1V90H@1239|Firmicutes,24B32@186801|Clostridia,3WQIB@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NFPJHIIC_00551	657322.FPR_05070	8.46e-198	547.0	COG2746@1|root,COG2746@2|Bacteria,1TT5E@1239|Firmicutes,25CER@186801|Clostridia,3WK3S@541000|Ruminococcaceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
NFPJHIIC_00552	657322.FPR_05060	1.49e-225	621.0	COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,1UK9F@1239|Firmicutes,25FRE@186801|Clostridia,3WSPZ@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFPJHIIC_00554	657322.FPR_05040	1.1e-144	408.0	2C1S2@1|root,2ZJNT@2|Bacteria,1V2MG@1239|Firmicutes,24KZ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00556	657322.FPR_05020	2.6e-184	512.0	2AYHW@1|root,2ZC56@2|Bacteria,1V2NU@1239|Firmicutes,24FWP@186801|Clostridia,3WRIM@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NFPJHIIC_00557	657322.FPR_20230	0.0	1670.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3WGZA@541000|Ruminococcaceae	186801|Clostridia	M	peptidoglycan binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,SpoIID
NFPJHIIC_00558	657322.FPR_20220	3.86e-172	479.0	COG3409@1|root,COG3409@2|Bacteria,1V14F@1239|Firmicutes,24ASJ@186801|Clostridia,3WK7I@541000|Ruminococcaceae	186801|Clostridia	M	peptidoglycan binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
NFPJHIIC_00559	657322.FPR_20210	3.37e-115	330.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3WIVQ@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
NFPJHIIC_00560	657322.FPR_20200	6.12e-230	633.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3WG9C@541000|Ruminococcaceae	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFPJHIIC_00562	657322.FPR_20180	5.25e-175	487.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
NFPJHIIC_00563	748224.HMPREF9436_00863	2.73e-86	256.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,3WSQI@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
NFPJHIIC_00564	657322.FPR_20160	1.21e-205	568.0	COG3947@1|root,COG3947@2|Bacteria,1URI4@1239|Firmicutes,24GP6@186801|Clostridia,3WJC3@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_00565	657322.FPR_20140	8.84e-43	139.0	COG4877@1|root,COG4877@2|Bacteria,1VEY1@1239|Firmicutes,24MV0@186801|Clostridia,3WKKV@541000|Ruminococcaceae	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like,RHH_5
NFPJHIIC_00566	657322.FPR_20130	5.06e-237	653.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,248UU@186801|Clostridia,3WI4C@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
NFPJHIIC_00567	657322.FPR_20120	2.67e-152	437.0	COG2379@1|root,COG2379@2|Bacteria,1TSQH@1239|Firmicutes,249XX@186801|Clostridia,3WGPY@541000|Ruminococcaceae	186801|Clostridia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
NFPJHIIC_00568	748224.HMPREF9436_02221	2.6e-188	523.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
NFPJHIIC_00569	411483.FAEPRAA2165_01090	2.65e-214	590.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,24A00@186801|Clostridia,3WGGI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
NFPJHIIC_00570	657322.FPR_14550	7.93e-248	680.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
NFPJHIIC_00571	657322.FPR_14560	9.45e-234	642.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,3WHMB@541000|Ruminococcaceae	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
NFPJHIIC_00572	657322.FPR_14570	6.98e-211	583.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,3WJGV@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFPJHIIC_00573	657322.FPR_14580	7.83e-159	444.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NFPJHIIC_00574	657322.FPR_14590	1.19e-154	434.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia,3WM22@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFPJHIIC_00575	411483.FAEPRAA2165_01540	8.96e-150	422.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia,3WHIR@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
NFPJHIIC_00576	657322.FPR_14610	6.38e-130	369.0	COG1309@1|root,COG1309@2|Bacteria,1V7CM@1239|Firmicutes,24K3K@186801|Clostridia,3WMJU@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00577	657322.FPR_14620	1.07e-60	192.0	2C176@1|root,2ZD1S@2|Bacteria,1W5ZC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00578	657322.FPR_14630	4.76e-159	447.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3WJ1B@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
NFPJHIIC_00579	657322.FPR_14640	4.57e-31	115.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3WINQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00580	657322.FPR_13740	6.48e-29	112.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
NFPJHIIC_00581	411483.FAEPRAA2165_02496	1.42e-70	211.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
NFPJHIIC_00582	657322.FPR_13760	6.86e-232	639.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase group 2 family protein	-	-	-	ko:K19427	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
NFPJHIIC_00583	657322.FPR_13770	0.0	895.0	2EIXX@1|root,338RG@2|Bacteria,1VJYN@1239|Firmicutes,25DS0@186801|Clostridia	186801|Clostridia	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
NFPJHIIC_00584	1280673.AUJJ01000012_gene1897	2.26e-93	290.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,4C0RF@830|Butyrivibrio	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NFPJHIIC_00585	657322.FPR_13790	2.89e-293	800.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
NFPJHIIC_00586	657322.FPR_13800	0.0	1167.0	COG3206@1|root,COG3206@2|Bacteria,1V867@1239|Firmicutes,24G2T@186801|Clostridia,3WRY8@541000|Ruminococcaceae	186801|Clostridia	M	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFPJHIIC_00587	657322.FPR_13810	9.14e-300	819.0	2EXX1@1|root,33R64@2|Bacteria,1VTQG@1239|Firmicutes,24Q1J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00588	657322.FPR_13820	1.31e-244	671.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJTI@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NFPJHIIC_00589	657322.FPR_04980	7.87e-303	843.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3WH08@541000|Ruminococcaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
NFPJHIIC_00590	657322.FPR_04970	6.09e-199	553.0	COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WG7J@541000|Ruminococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
NFPJHIIC_00591	657322.FPR_04960	3.16e-178	496.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,3WNRZ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
NFPJHIIC_00592	657322.FPR_04950	5.48e-236	649.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WGP5@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NFPJHIIC_00593	657322.FPR_04940	0.0	1658.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NFPJHIIC_00594	657322.FPR_04930	7.31e-38	126.0	COG1141@1|root,COG1141@2|Bacteria,1VGNV@1239|Firmicutes,259E5@186801|Clostridia,3WQRA@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
NFPJHIIC_00595	657322.FPR_04920	2.64e-79	235.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3WK00@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
NFPJHIIC_00596	657322.FPR_04910	4.34e-189	528.0	2EC5R@1|root,3364D@2|Bacteria,1VGAK@1239|Firmicutes,24SS9@186801|Clostridia,3WKX9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00597	657322.FPR_04900	1.22e-247	679.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3WIR8@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
NFPJHIIC_00598	657322.FPR_04890	1.61e-45	150.0	2BVE9@1|root,32QU0@2|Bacteria,1V90X@1239|Firmicutes,24KRK@186801|Clostridia,3WQ96@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
NFPJHIIC_00599	748224.HMPREF9436_00889	4.07e-49	171.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3WGCV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	apu	-	2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R02112,R03122,R05196,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31,GH77	-	Alpha-amylase,Alpha-amylase_N,Glyco_hydro_77,Malt_amylase_C
NFPJHIIC_00600	657322.FPR_21460	1.7e-101	294.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3WKQY@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NFPJHIIC_00601	657322.FPR_21450	1.82e-155	443.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NFPJHIIC_00603	657322.FPR_21430	0.0	877.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3WHCB@541000|Ruminococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NFPJHIIC_00604	748224.HMPREF9436_01339	0.0	1166.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3WGZ4@541000|Ruminococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
NFPJHIIC_00605	748224.HMPREF9436_01338	1.12e-248	697.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WGTJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NFPJHIIC_00606	657322.FPR_21400	5.73e-202	558.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3WGBQ@541000|Ruminococcaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
NFPJHIIC_00607	657322.FPR_10440	1.92e-209	580.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3WGGT@541000|Ruminococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NFPJHIIC_00608	657322.FPR_10430	2.17e-145	409.0	COG0454@1|root,COG0456@2|Bacteria,1VGV3@1239|Firmicutes,24RSS@186801|Clostridia,3WKI5@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFPJHIIC_00609	657322.FPR_10420	2.2e-170	476.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3WKKW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NFPJHIIC_00610	657322.FPR_10410	0.0	1194.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NFPJHIIC_00611	657322.FPR_10400	1.71e-300	822.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
NFPJHIIC_00612	657322.FPR_10390	3.26e-68	206.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NFPJHIIC_00613	657322.FPR_10380	0.0	1067.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3WGXZ@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
NFPJHIIC_00615	657322.FPR_31130	7.52e-82	249.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3WGB3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NFPJHIIC_00616	657322.FPR_31120	9.9e-209	577.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
NFPJHIIC_00617	748224.HMPREF9436_01517	7.58e-187	521.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
NFPJHIIC_00618	657322.FPR_31090	7.3e-217	599.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3WHUA@541000|Ruminococcaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NFPJHIIC_00619	657322.FPR_31080	0.0	2323.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NFPJHIIC_00620	657322.FPR_31070	2.6e-233	642.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NFPJHIIC_00621	657322.FPR_31060	3.56e-86	253.0	COG2315@1|root,COG2315@2|Bacteria,1V79C@1239|Firmicutes,257W8@186801|Clostridia,3WK2N@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NFPJHIIC_00622	657322.FPR_31050	2.45e-47	157.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3WGC2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
NFPJHIIC_00623	657322.FPR_31050	5.91e-75	227.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3WGC2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
NFPJHIIC_00624	657322.FPR_18260	3.98e-93	284.0	COG3757@1|root,COG3757@2|Bacteria,1V4GP@1239|Firmicutes,24FYR@186801|Clostridia,3WIS8@541000|Ruminococcaceae	186801|Clostridia	M	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Glyco_hydro_25,SH3_3
NFPJHIIC_00625	657322.FPR_18250	2.26e-135	385.0	2BB2P@1|root,324IU@2|Bacteria,1UQTN@1239|Firmicutes,257SI@186801|Clostridia,3WMSF@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4830
NFPJHIIC_00626	657322.FPR_18240	1.72e-53	167.0	COG1925@1|root,COG1925@2|Bacteria,1VYCG@1239|Firmicutes,251I2@186801|Clostridia,3WKJQ@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NFPJHIIC_00627	657322.FPR_18230	0.0	1053.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WGQS@541000|Ruminococcaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NFPJHIIC_00628	657322.FPR_18220	1.7e-113	325.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3WRU9@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFPJHIIC_00629	657322.FPR_18210	4.33e-153	430.0	COG5660@1|root,COG5660@2|Bacteria,1VKXY@1239|Firmicutes,24UK9@186801|Clostridia,3WMGN@541000|Ruminococcaceae	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NFPJHIIC_00632	657322.FPR_18170	8.94e-308	839.0	COG0739@1|root,COG0739@2|Bacteria,1V7QV@1239|Firmicutes,24M4A@186801|Clostridia,3WNIT@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NFPJHIIC_00633	657322.FPR_18160	3.6e-30	107.0	28ZEN@1|root,2ZM68@2|Bacteria,1W2T3@1239|Firmicutes,257D2@186801|Clostridia,3WRA6@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00634	748224.HMPREF9436_02018	2.24e-209	583.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
NFPJHIIC_00635	657322.FPR_18140	5.76e-252	695.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3WGDY@541000|Ruminococcaceae	186801|Clostridia	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NFPJHIIC_00636	657322.FPR_16840	1.24e-62	192.0	COG0776@1|root,COG0776@2|Bacteria,1VZ6B@1239|Firmicutes,253S5@186801|Clostridia,3WQ7M@541000|Ruminococcaceae	186801|Clostridia	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NFPJHIIC_00637	657322.FPR_16830	0.0	2186.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
NFPJHIIC_00638	657322.FPR_16820	1.18e-274	750.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WH1G@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NFPJHIIC_00639	657322.FPR_16810	5.13e-138	390.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,3WJAM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NFPJHIIC_00640	657322.FPR_16800	4.4e-217	599.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NFPJHIIC_00641	657322.FPR_16790	3.86e-190	527.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3WGW1@541000|Ruminococcaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iHN637.CLJU_RS17580	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NFPJHIIC_00642	718252.FP2_15390	4.37e-207	572.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3WH6X@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
NFPJHIIC_00643	657322.FPR_16760	1.83e-266	730.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3WGV4@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NFPJHIIC_00644	748224.HMPREF9436_00979	6.64e-190	527.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.3.1.108	ko:K03521,ko:K22431	-	-	-	-	ko00000,ko01000	-	-	-	ETF
NFPJHIIC_00645	657322.FPR_29610	3.01e-274	751.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
NFPJHIIC_00646	657322.FPR_29600	6.21e-208	575.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
NFPJHIIC_00647	657322.FPR_29590	5.43e-183	509.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3WI8Y@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
NFPJHIIC_00648	657322.FPR_29580	6.18e-282	771.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
NFPJHIIC_00649	657322.FPR_29570	4.65e-123	351.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3WJBF@541000|Ruminococcaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NFPJHIIC_00650	657322.FPR_29560	0.0	897.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase C-terminal domain	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
NFPJHIIC_00651	657322.FPR_29550	5.11e-270	743.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3WGFR@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NFPJHIIC_00652	657322.FPR_29940	6.35e-126	358.0	COG0454@1|root,COG0456@2|Bacteria,1VGZX@1239|Firmicutes,24I40@186801|Clostridia,3WMBR@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFPJHIIC_00653	657322.FPR_29930	5e-174	486.0	COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,24C86@186801|Clostridia,3WJ26@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
NFPJHIIC_00654	657322.FPR_29920	3.13e-224	618.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NFPJHIIC_00655	657322.FPR_29910	4.43e-100	290.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3WIXA@541000|Ruminococcaceae	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
NFPJHIIC_00656	657322.FPR_29900	1.38e-309	843.0	COG3290@1|root,COG3290@2|Bacteria,1UZ59@1239|Firmicutes,24A0V@186801|Clostridia,3WMIF@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFPJHIIC_00657	657322.FPR_29890	8.72e-174	484.0	COG3279@1|root,COG3279@2|Bacteria,1UYHU@1239|Firmicutes,24CBK@186801|Clostridia,3WRIR@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFPJHIIC_00658	748224.HMPREF9436_01275	3.98e-297	814.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFPJHIIC_00659	657322.FPR_29870	3.01e-187	521.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3WHAC@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFPJHIIC_00660	657322.FPR_29860	2.97e-86	254.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,3WJU2@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
NFPJHIIC_00661	657322.FPR_29850	2.05e-148	420.0	2DPRU@1|root,3334J@2|Bacteria,1VGDR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
NFPJHIIC_00662	657322.FPR_29840	2.44e-64	199.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
NFPJHIIC_00663	657322.FPR_05280	3.52e-151	426.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3WIYG@541000|Ruminococcaceae	186801|Clostridia	P	Molybdate ABC transporter	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
NFPJHIIC_00664	657322.FPR_05270	5.53e-243	668.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
NFPJHIIC_00665	657322.FPR_05260	4.52e-81	239.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia	186801|Clostridia	S	protein with conserved CXXC pairs	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
NFPJHIIC_00666	657322.FPR_05250	1.1e-297	812.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,3WHBX@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
NFPJHIIC_00667	657322.FPR_05240	0.0	945.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,3WH8P@541000|Ruminococcaceae	186801|Clostridia	C	FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
NFPJHIIC_00668	657322.FPR_05230	1.12e-123	353.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,3WPST@541000|Ruminococcaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
NFPJHIIC_00669	657322.FPR_05220	1.34e-301	821.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFPJHIIC_00670	657322.FPR_05210	0.0	1634.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NFPJHIIC_00671	657322.FPR_12680	3.06e-195	548.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NFPJHIIC_00673	657322.FPR_12710	0.0	1364.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
NFPJHIIC_00674	748224.HMPREF9436_01369	6.78e-131	379.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NFPJHIIC_00675	748224.HMPREF9436_01370	0.0	1231.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WST3@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SBP_bac_3,SnoaL_3
NFPJHIIC_00676	657322.FPR_12740	1.98e-166	468.0	COG0111@1|root,COG0111@2|Bacteria,1TPUC@1239|Firmicutes,253BG@186801|Clostridia,3WJ87@541000|Ruminococcaceae	186801|Clostridia	EH	dipicolinic acid synthetase, A subunit	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N
NFPJHIIC_00677	657322.FPR_12750	7.84e-133	377.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia,3WHFH@541000|Ruminococcaceae	186801|Clostridia	H	Dipicolinic acid synthetase, B subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
NFPJHIIC_00678	657322.FPR_14890	2.55e-166	466.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NFPJHIIC_00679	657322.FPR_14880	1.26e-217	601.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NFPJHIIC_00680	657322.FPR_14870	3.65e-251	689.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3WRV6@541000|Ruminococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
NFPJHIIC_00681	657322.FPR_14860	7.25e-213	589.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,3WGKK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
NFPJHIIC_00682	657322.FPR_14850	2.51e-211	585.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3WHBA@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
NFPJHIIC_00683	657322.FPR_14840	5.43e-228	628.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,3WSKG@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
NFPJHIIC_00684	657322.FPR_14830	9.52e-205	566.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3WGZ8@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
NFPJHIIC_00685	657322.FPR_14820	3.48e-44	143.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFPJHIIC_00686	657322.FPR_14810	2.05e-304	832.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WHE3@541000|Ruminococcaceae	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NFPJHIIC_00688	748224.HMPREF9436_02394	1.98e-232	644.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NFPJHIIC_00689	657322.FPR_16700	3.41e-312	851.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WNCZ@541000|Ruminococcaceae	186801|Clostridia	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NFPJHIIC_00690	657322.FPR_16710	3.23e-254	700.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NFPJHIIC_00692	657322.FPR_16730	0.0	1571.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WIEK@541000|Ruminococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,PAS_3,Response_reg
NFPJHIIC_00693	657322.FPR_16740	2.78e-60	190.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3WHD9@541000|Ruminococcaceae	186801|Clostridia	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
NFPJHIIC_00695	657322.FPR_03900	1.59e-115	331.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3WK62@541000|Ruminococcaceae	186801|Clostridia	S	Mitochondrial PGP phosphatase	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
NFPJHIIC_00696	411483.FAEPRAA2165_01681	5.46e-27	99.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3WKHJ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NFPJHIIC_00697	657322.FPR_03880	0.0	1747.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NFPJHIIC_00698	657322.FPR_03870	1.39e-83	247.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3WJVU@541000|Ruminococcaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
NFPJHIIC_00699	657322.FPR_03860	3.09e-282	775.0	COG1316@1|root,COG1316@2|Bacteria,1VBCT@1239|Firmicutes,25MDF@186801|Clostridia,3WKBP@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NFPJHIIC_00700	657322.FPR_03840	1.08e-132	376.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3WJZX@541000|Ruminococcaceae	186801|Clostridia	H	HD superfamily hydrolase involved in NAD metabolism	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
NFPJHIIC_00701	657322.FPR_03830	9.43e-146	411.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3WJ7X@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NFPJHIIC_00702	657322.FPR_03820	1.79e-61	189.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3WKIM@541000|Ruminococcaceae	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
NFPJHIIC_00703	657322.FPR_03810	5.4e-73	222.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NFPJHIIC_00705	748224.HMPREF9436_03314	0.0	978.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGTD@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFPJHIIC_00706	657322.FPR_12180	1.8e-248	684.0	COG0790@1|root,COG0790@2|Bacteria,1VEK9@1239|Firmicutes	1239|Firmicutes	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
NFPJHIIC_00707	657322.FPR_12190	0.0	1138.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,24CZN@186801|Clostridia,3WMZG@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NFPJHIIC_00708	657322.FPR_12200	3.2e-49	156.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia,3WKND@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
NFPJHIIC_00709	657322.FPR_12210	4.39e-225	622.0	2DBS1@1|root,2ZANX@2|Bacteria,1UZPQ@1239|Firmicutes,24D5T@186801|Clostridia,3WMAI@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00710	657322.FPR_12220	1.8e-76	231.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,3WISA@541000|Ruminococcaceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
NFPJHIIC_00711	657322.FPR_12230	7.92e-15	72.8	COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,248GG@186801|Clostridia,3WN10@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,TAT_signal
NFPJHIIC_00712	657322.FPR_28740	8.57e-188	523.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3WI77@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NFPJHIIC_00713	657322.FPR_28730	3.93e-181	505.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3WHJ9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NFPJHIIC_00714	657322.FPR_28720	8.61e-251	688.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NFPJHIIC_00715	657322.FPR_28710	2.78e-208	578.0	2B6VY@1|root,31ZVP@2|Bacteria,1V9UC@1239|Firmicutes,25DFR@186801|Clostridia,3WSGI@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
NFPJHIIC_00716	657322.FPR_28700	2.28e-90	277.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3WIU9@541000|Ruminococcaceae	186801|Clostridia	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
NFPJHIIC_00718	657322.FPR_28690	3.33e-187	522.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3WI9V@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3
NFPJHIIC_00719	748224.HMPREF9436_00109	8.91e-174	491.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFPJHIIC_00720	411483.FAEPRAA2165_01623	2.24e-45	145.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NFPJHIIC_00721	657322.FPR_21300	0.0	1765.0	COG5434@1|root,COG5434@2|Bacteria,1UFEM@1239|Firmicutes,24EYH@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
NFPJHIIC_00722	748224.HMPREF9436_00103	5.8e-170	482.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia	186801|Clostridia	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFPJHIIC_00723	657322.FPR_21280	5.82e-183	510.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24FGY@186801|Clostridia,3WRMJ@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NFPJHIIC_00724	657322.FPR_21270	0.0	968.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NFPJHIIC_00725	657322.FPR_21260	5.47e-125	355.0	2EDD1@1|root,3379C@2|Bacteria,1W2ES@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00726	657322.FPR_21250	4.09e-157	452.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3WGE9@541000|Ruminococcaceae	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NFPJHIIC_00728	657322.FPR_17910	9.72e-121	345.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3WITH@541000|Ruminococcaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
NFPJHIIC_00729	657322.FPR_17900	1.41e-255	706.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,3WHRI@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NFPJHIIC_00730	657322.FPR_17890	2.67e-144	408.0	COG4720@1|root,COG4720@2|Bacteria,1USKD@1239|Firmicutes,24A2K@186801|Clostridia,3WKAY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NFPJHIIC_00731	657322.FPR_17880	0.0	930.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WHQS@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
NFPJHIIC_00732	748224.HMPREF9436_00673	1.68e-116	343.0	2FCAY@1|root,344EI@2|Bacteria,1VZI3@1239|Firmicutes,252RF@186801|Clostridia,3WQBB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00734	657322.FPR_17840	0.0	876.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WH5C@541000|Ruminococcaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFPJHIIC_00735	657322.FPR_14900	3.03e-52	174.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NFPJHIIC_00736	657322.FPR_14910	7.17e-109	313.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3WJ8D@541000|Ruminococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
NFPJHIIC_00737	657322.FPR_14920	8.89e-246	675.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
NFPJHIIC_00738	657322.FPR_14930	0.0	999.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
NFPJHIIC_00739	657322.FPR_14940	4.77e-216	595.0	COG0152@1|root,COG0152@2|Bacteria,1VTBC@1239|Firmicutes,24ZTC@186801|Clostridia,3WH16@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
NFPJHIIC_00740	657322.FPR_14950	8.99e-114	326.0	COG1846@1|root,COG1846@2|Bacteria,1VA2S@1239|Firmicutes,25CPK@186801|Clostridia,3WM6Y@541000|Ruminococcaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
NFPJHIIC_00741	657322.FPR_14960	0.0	1067.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGE4@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFPJHIIC_00744	657322.FPR_20630	5.38e-131	372.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24JF9@186801|Clostridia,3WJRT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
NFPJHIIC_00745	657322.FPR_20640	1.24e-47	152.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,3WKHX@541000|Ruminococcaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NFPJHIIC_00746	657322.FPR_20650	1.37e-173	485.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3WGQ0@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NFPJHIIC_00747	657322.FPR_20660	6.54e-157	441.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3WGM5@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NFPJHIIC_00748	748224.HMPREF9436_02912	6e-105	313.0	2APHA@1|root,31EK9@2|Bacteria,1VIZ2@1239|Firmicutes,258XE@186801|Clostridia,3WKUY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U4
NFPJHIIC_00750	657322.FPR_20700	0.0	1261.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NFPJHIIC_00751	657322.FPR_20710	1.19e-77	231.0	COG5341@1|root,COG5341@2|Bacteria,1VII9@1239|Firmicutes,24SGZ@186801|Clostridia,3WQHY@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
NFPJHIIC_00753	314265.R2601_26956	1.06e-40	165.0	28J1Q@1|root,2Z8YK@2|Bacteria,1R29N@1224|Proteobacteria,2TV1C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00754	657322.FPR_24640	1.67e-117	337.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3WK8P@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
NFPJHIIC_00755	657322.FPR_24630	0.0	1219.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WGHX@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NFPJHIIC_00756	657322.FPR_24620	1.33e-171	479.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,24HKY@186801|Clostridia,3WJVM@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFPJHIIC_00758	657322.FPR_24600	0.0	954.0	COG2755@1|root,COG2755@2|Bacteria,1VG8J@1239|Firmicutes,24RJ2@186801|Clostridia,3WNI1@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Lipase_GDSL_2
NFPJHIIC_00759	748224.HMPREF9436_01043	7.2e-130	372.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFPJHIIC_00760	657322.FPR_24580	2.71e-72	217.0	2E9SM@1|root,333YT@2|Bacteria,1VNW8@1239|Firmicutes,25BUJ@186801|Clostridia,3WS91@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00761	657322.FPR_21110	5.52e-176	498.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,3WGKT@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
NFPJHIIC_00762	657322.FPR_21120	8.01e-255	698.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NFPJHIIC_00763	657322.FPR_21130	2.78e-65	199.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3WJUU@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NFPJHIIC_00764	411483.FAEPRAA2165_02204	8.65e-53	166.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3WJU0@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NFPJHIIC_00765	657322.FPR_21150	1.27e-315	858.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WH1H@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
NFPJHIIC_00766	657322.FPR_21160	4.57e-90	264.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
NFPJHIIC_00768	657322.FPR_21180	0.0	1012.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NFPJHIIC_00769	657322.FPR_21190	4.12e-170	475.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WHDN@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NFPJHIIC_00770	657322.FPR_21200	6.15e-57	176.0	COG4115@1|root,COG4115@2|Bacteria,1VAM5@1239|Firmicutes,24N6K@186801|Clostridia	186801|Clostridia	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	YoeB_toxin
NFPJHIIC_00771	657322.FPR_21210	1.9e-51	162.0	COG2161@1|root,COG2161@2|Bacteria,1VCZ4@1239|Firmicutes,24PB9@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
NFPJHIIC_00772	657322.FPR_06680	0.0	1571.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NFPJHIIC_00773	657322.FPR_06690	1.14e-74	223.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3WJJW@541000|Ruminococcaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NFPJHIIC_00774	657322.FPR_06700	6.61e-123	350.0	COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,25QBJ@186801|Clostridia,3WIP6@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
NFPJHIIC_00775	657322.FPR_06710	0.0	1216.0	COG0658@1|root,COG0658@2|Bacteria,1VGSX@1239|Firmicutes,249H4@186801|Clostridia,3WKE7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
NFPJHIIC_00776	657322.FPR_06720	9.44e-236	649.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3WJ8A@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NFPJHIIC_00777	657322.FPR_06730	5.09e-139	393.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,3WIWX@541000|Ruminococcaceae	186801|Clostridia	L	Ribonuclease M5	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
NFPJHIIC_00778	748224.HMPREF9436_03175	1.85e-75	231.0	COG1191@1|root,COG1191@2|Bacteria,1VZE1@1239|Firmicutes,25442@186801|Clostridia,3WQK3@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
NFPJHIIC_00779	657322.FPR_29630	7.15e-127	368.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae	186801|Clostridia	C	Electron transfer flavoprotein FAD-binding domain	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
NFPJHIIC_00780	657322.FPR_29640	7.11e-225	619.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia,3WK59@541000|Ruminococcaceae	186801|Clostridia	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Dockerin_1
NFPJHIIC_00781	748224.HMPREF9436_00983	4.27e-130	371.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
NFPJHIIC_00782	657322.FPR_29660	1.72e-242	665.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3WG8N@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
NFPJHIIC_00783	657322.FPR_29670	0.0	1151.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
NFPJHIIC_00784	657322.FPR_29680	2.62e-242	667.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NFPJHIIC_00786	657322.FPR_18080	4.65e-71	214.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NFPJHIIC_00787	657322.FPR_18070	1.01e-228	631.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
NFPJHIIC_00788	657322.FPR_18060	7.85e-96	280.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3WJNA@541000|Ruminococcaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NFPJHIIC_00789	657322.FPR_18050	1.04e-181	507.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia,3WIZM@541000|Ruminococcaceae	186801|Clostridia	M	Serine-type D-Ala-D-Ala carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Big_2,VanY
NFPJHIIC_00790	657322.FPR_18040	1.15e-82	249.0	2C9HT@1|root,2ZDJ9@2|Bacteria,1W4SA@1239|Firmicutes,255IW@186801|Clostridia,3WQUU@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
NFPJHIIC_00791	748224.HMPREF9436_02030	0.0	904.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
NFPJHIIC_00792	657322.FPR_18020	3.17e-281	768.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
NFPJHIIC_00795	657322.FPR_17970	5.67e-45	155.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3WH82@541000|Ruminococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
NFPJHIIC_00796	657322.FPR_02220	1.55e-212	594.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NFPJHIIC_00797	748224.HMPREF9436_01646	0.0	1259.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3WGNX@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFPJHIIC_00798	657322.FPR_02200	1.02e-169	473.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFPJHIIC_00799	657322.FPR_02190	0.0	1268.0	COG3509@1|root,COG3509@2|Bacteria,1V9NZ@1239|Firmicutes,24RU6@186801|Clostridia,3WPZX@541000|Ruminococcaceae	186801|Clostridia	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
NFPJHIIC_00800	748224.HMPREF9436_02584	3.35e-105	312.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
NFPJHIIC_00801	657322.FPR_11240	1.68e-145	421.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WH1I@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFPJHIIC_00803	657322.FPR_11220	3.05e-235	646.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia,3WJP8@541000|Ruminococcaceae	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
NFPJHIIC_00804	748224.HMPREF9436_00247	0.0	1125.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
NFPJHIIC_00805	657322.FPR_11180	1.06e-66	201.0	29PJD@1|root,30AHI@2|Bacteria,1VC64@1239|Firmicutes,24N2Y@186801|Clostridia,3WQ27@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
NFPJHIIC_00806	657322.FPR_11170	5.13e-64	194.0	2B2ZF@1|root,32PN8@2|Bacteria,1V7B5@1239|Firmicutes,24JQY@186801|Clostridia,3WKHW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00807	657322.FPR_11160	0.0	995.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WGJQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NFPJHIIC_00808	657322.FPR_11150	4.43e-56	176.0	2DZF8@1|root,32V97@2|Bacteria,1VK00@1239|Firmicutes,24NVD@186801|Clostridia,3WM6X@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00809	657322.FPR_11150	6.96e-19	80.1	2DZF8@1|root,32V97@2|Bacteria,1VK00@1239|Firmicutes,24NVD@186801|Clostridia,3WM6X@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00810	657322.FPR_11140	7.68e-39	129.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3WKZF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NFPJHIIC_00811	657322.FPR_11130	2.61e-57	195.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,2486F@186801|Clostridia,3WGI2@541000|Ruminococcaceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
NFPJHIIC_00812	657322.FPR_10600	3.16e-79	243.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14395	DAHP_synth_1
NFPJHIIC_00813	657322.FPR_10590	4.68e-298	814.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
NFPJHIIC_00814	657322.FPR_10580	6.99e-208	574.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3WI06@541000|Ruminococcaceae	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
NFPJHIIC_00815	657322.FPR_10570	1.98e-234	644.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,3WH18@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	WYL
NFPJHIIC_00816	657322.FPR_10560	0.0	1286.0	COG0464@1|root,COG0542@1|root,COG0464@2|Bacteria,COG0542@2|Bacteria,1TPQZ@1239|Firmicutes,24BQK@186801|Clostridia,3WGEZ@541000|Ruminococcaceae	186801|Clostridia	O	ATPase, AAA family	-	-	-	-	-	-	-	-	-	-	-	-	AAA
NFPJHIIC_00817	657322.FPR_10550	2.31e-52	170.0	2CHRH@1|root,2ZES1@2|Bacteria,1W4VA@1239|Firmicutes,257KM@186801|Clostridia,3WRBD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00818	657322.FPR_10540	1.03e-237	652.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NFPJHIIC_00819	657322.FPR_10530	1.78e-53	178.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3WGTH@541000|Ruminococcaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NFPJHIIC_00821	657322.FPR_30560	1.43e-249	684.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WGMR@541000|Ruminococcaceae	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
NFPJHIIC_00822	657322.FPR_30550	1.53e-266	729.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WGVU@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NFPJHIIC_00823	657322.FPR_30540	2.35e-211	584.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3WGWA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NFPJHIIC_00824	657322.FPR_30530	2.6e-181	504.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
NFPJHIIC_00825	657322.FPR_30520	2.97e-304	830.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NFPJHIIC_00826	657322.FPR_30510	1.9e-99	289.0	COG0527@1|root,COG0527@2|Bacteria,1V6AQ@1239|Firmicutes,24PYP@186801|Clostridia,3WKNF@541000|Ruminococcaceae	186801|Clostridia	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_7
NFPJHIIC_00827	657322.FPR_30500	9.63e-130	369.0	COG2190@1|root,COG2190@2|Bacteria,1W092@1239|Firmicutes,25EGH@186801|Clostridia,3WSQZ@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
NFPJHIIC_00828	657322.FPR_30490	2.88e-65	209.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
NFPJHIIC_00829	657322.FPR_30130	1.66e-73	220.0	29NZE@1|root,309XJ@2|Bacteria	2|Bacteria	S	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_4
NFPJHIIC_00830	657322.FPR_30120	0.0	939.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NFPJHIIC_00831	657322.FPR_30110	1.09e-33	120.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
NFPJHIIC_00832	657322.FPR_30100	3.81e-268	739.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
NFPJHIIC_00833	748224.HMPREF9436_01003	2.61e-207	602.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,3WS66@541000|Ruminococcaceae	186801|Clostridia	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
NFPJHIIC_00834	657322.FPR_30080	8.45e-210	581.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NFPJHIIC_00835	657322.FPR_30070	8.96e-90	267.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NFPJHIIC_00836	657322.FPR_31040	1.86e-202	570.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
NFPJHIIC_00837	657322.FPR_30880	3.23e-153	432.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3WIDD@541000|Ruminococcaceae	186801|Clostridia	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
NFPJHIIC_00838	657322.FPR_30870	3.04e-59	183.0	2CCD5@1|root,32RVD@2|Bacteria,1UPQI@1239|Firmicutes,25HM0@186801|Clostridia,3WREV@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
NFPJHIIC_00839	657322.FPR_30860	2.6e-194	539.0	COG1091@1|root,COG1091@2|Bacteria,1TQSX@1239|Firmicutes,24G9Q@186801|Clostridia,3WN5F@541000|Ruminococcaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NFPJHIIC_00840	748224.HMPREF9436_01593	8.42e-302	827.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3WGM2@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
NFPJHIIC_00841	657322.FPR_30830	5.17e-142	402.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NFPJHIIC_00842	657322.FPR_30820	3.93e-179	500.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NFPJHIIC_00843	657322.FPR_30810	3.16e-112	322.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3WJ5N@541000|Ruminococcaceae	186801|Clostridia	C	[2Fe-2S] binding domain	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NFPJHIIC_00844	748224.HMPREF9436_02899	1.92e-141	413.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WGJC@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00845	718252.FP2_01780	0.0	1081.0	COG1511@1|root,COG1511@2|Bacteria,1TPMH@1239|Firmicutes,249KI@186801|Clostridia,3WHUZ@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glug
NFPJHIIC_00846	1519439.JPJG01000022_gene547	0.0	974.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,2N6D3@216572|Oscillospiraceae	186801|Clostridia	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NFPJHIIC_00847	748224.HMPREF9436_03256	1.72e-40	137.0	2EFE1@1|root,3396U@2|Bacteria,1VK14@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00848	657322.FPR_17830	6.4e-134	389.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00849	657322.FPR_17820	6.26e-290	791.0	COG0657@1|root,COG0657@2|Bacteria,1UEU5@1239|Firmicutes,24BRQ@186801|Clostridia	2|Bacteria	I	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NFPJHIIC_00850	657322.FPR_17810	3.89e-207	572.0	COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,24CT5@186801|Clostridia,3WHUG@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase	rlmA	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
NFPJHIIC_00851	657322.FPR_17800	0.0	966.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3WGP7@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
NFPJHIIC_00852	657322.FPR_17790	0.0	881.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,3WGM6@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NFPJHIIC_00853	657322.FPR_17780	9.43e-228	631.0	COG1306@1|root,COG1306@2|Bacteria,1UFJZ@1239|Firmicutes,24TYT@186801|Clostridia,3WJIH@541000|Ruminococcaceae	186801|Clostridia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
NFPJHIIC_00854	748224.HMPREF9436_00453	8.76e-36	126.0	COG4657@1|root,COG4657@2|Bacteria,1VE3F@1239|Firmicutes,24PA9@186801|Clostridia,3WM1P@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NFPJHIIC_00855	657322.FPR_08840	3.17e-156	438.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NFPJHIIC_00856	657322.FPR_08850	1.35e-239	657.0	COG0008@1|root,COG0008@2|Bacteria,1TVW7@1239|Firmicutes,24BG2@186801|Clostridia,3WHX2@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NFPJHIIC_00857	657322.FPR_08860	0.0	914.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,3WNWV@541000|Ruminococcaceae	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	3.2.1.122,3.2.1.86	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	-	R00837,R00838,R00839,R05133,R05134,R06113	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GH4,GT4	-	Glyco_hydro_4,Glyco_hydro_4C
NFPJHIIC_00858	657322.FPR_08870	0.0	1010.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WN0C@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	glvC	-	2.7.1.199,2.7.1.208	ko:K02749,ko:K02750,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	M00266,M00268	R02738,R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.10,4.A.1.1.16,4.A.1.1.3,4.A.1.1.4,4.A.1.1.8	-	-	PTS_EIIB,PTS_EIIC
NFPJHIIC_00859	657322.FPR_08880	5.24e-191	530.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,3WIEJ@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	licT	-	-	ko:K03480,ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NFPJHIIC_00860	657322.FPR_08890	3.41e-115	333.0	2EHNH@1|root,33BEA@2|Bacteria,1VQC1@1239|Firmicutes,24X4U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00861	657322.FPR_08900	4.87e-132	382.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3WGBS@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
NFPJHIIC_00862	657322.FPR_30480	0.0	991.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
NFPJHIIC_00863	657322.FPR_30470	6.8e-110	316.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
NFPJHIIC_00864	657322.FPR_30460	2.51e-199	552.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3WHYS@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
NFPJHIIC_00865	748224.HMPREF9436_01556	8.86e-176	491.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NFPJHIIC_00866	657322.FPR_30440	0.0	1269.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WGVF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NFPJHIIC_00867	657322.FPR_30430	1.39e-101	295.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,3WJXW@541000|Ruminococcaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
NFPJHIIC_00868	657322.FPR_30420	1.19e-156	442.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
NFPJHIIC_00870	748224.HMPREF9436_00533	7.03e-213	587.0	2DT94@1|root,33J9A@2|Bacteria,1W4B6@1239|Firmicutes,256YX@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4428
NFPJHIIC_00871	657322.FPR_07770	4.62e-298	818.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WHZY@541000|Ruminococcaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
NFPJHIIC_00873	411483.FAEPRAA2165_03118	4.46e-305	838.0	2EJ3B@1|root,33CUJ@2|Bacteria,1VZS4@1239|Firmicutes,253ZC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00874	657322.FPR_13550	1.25e-243	671.0	COG5492@1|root,COG5492@2|Bacteria,1VKK8@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Laminin_G_3,SLH
NFPJHIIC_00876	657322.FPR_13570	4.35e-94	274.0	COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia	186801|Clostridia	M	Peptidase M15A	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
NFPJHIIC_00877	748224.HMPREF9436_00408	1.29e-31	112.0	2DRAZ@1|root,33B0U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00878	657322.FPR_13590	6.31e-51	161.0	2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,24S49@186801|Clostridia,3WQWC@541000|Ruminococcaceae	186801|Clostridia	S	SPP1 phage holin	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
NFPJHIIC_00879	657322.FPR_13600	6.16e-131	372.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3WJNY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NFPJHIIC_00880	657322.FPR_13610	7.53e-239	656.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia,3WNFX@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase NAD-binding domain protein	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFPJHIIC_00881	657322.FPR_13620	1.86e-212	587.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
NFPJHIIC_00882	657322.FPR_13630	9.83e-280	765.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WGXA@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
NFPJHIIC_00883	748224.HMPREF9436_01345	0.0	1805.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WGS6@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NFPJHIIC_00884	657322.FPR_26430	0.0	1308.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NFPJHIIC_00885	657322.FPR_26420	2.59e-170	475.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3WJ3Y@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	HHH,RadC
NFPJHIIC_00886	657322.FPR_26410	3.89e-242	664.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3WH5D@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFPJHIIC_00887	657322.FPR_10050	6.15e-40	131.0	2EGE3@1|root,33A60@2|Bacteria	2|Bacteria	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00888	657322.FPR_10040	2.72e-189	525.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3WIGB@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NFPJHIIC_00889	657322.FPR_10030	5.52e-285	778.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NFPJHIIC_00890	657322.FPR_10020	0.0	1073.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NFPJHIIC_00891	657322.FPR_10010	2.26e-193	536.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	ytrP	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF_2,GAF_3,GGDEF,HAMP
NFPJHIIC_00892	657322.FPR_10000	6.26e-96	280.0	2BRQ4@1|root,32KPS@2|Bacteria,1V8GJ@1239|Firmicutes,24JFQ@186801|Clostridia,3WKHT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00893	657322.FPR_09990	1.46e-220	607.0	COG1208@1|root,COG1208@2|Bacteria,1UIRX@1239|Firmicutes,25EQU@186801|Clostridia,3WHF0@541000|Ruminococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
NFPJHIIC_00894	657322.FPR_29950	0.0	1653.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NFPJHIIC_00895	657322.FPR_29960	2.69e-182	507.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,3WGNR@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
NFPJHIIC_00896	657322.FPR_29970	6.41e-163	455.0	COG0125@1|root,COG0125@2|Bacteria,1V2D5@1239|Firmicutes,25CJJ@186801|Clostridia,3WIE4@541000|Ruminococcaceae	186801|Clostridia	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
NFPJHIIC_00897	657322.FPR_29980	2.13e-189	526.0	2F8HG@1|root,340WA@2|Bacteria,1VXQT@1239|Firmicutes,2529I@186801|Clostridia,3WPPF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00898	657322.FPR_29990	1.75e-257	707.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,3WHZ1@541000|Ruminococcaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
NFPJHIIC_00899	748224.HMPREF9436_00757	1.06e-51	165.0	COG0745@1|root,COG0745@2|Bacteria,1VH87@1239|Firmicutes,24T6J@186801|Clostridia,3WQ3D@541000|Ruminococcaceae	186801|Clostridia	KT	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NFPJHIIC_00901	748224.HMPREF9436_00541	0.0	985.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NFPJHIIC_00902	748224.HMPREF9436_00540	1.3e-243	671.0	2A16U@1|root,30PCV@2|Bacteria,1UQIU@1239|Firmicutes,258AC@186801|Clostridia,3WMB4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00905	748224.HMPREF9436_00536	3.8e-173	486.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,25CUP@186801|Clostridia,3WJ66@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
NFPJHIIC_00906	657322.FPR_07800	3.18e-103	306.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00908	411483.FAEPRAA2165_02255	2.93e-313	855.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,3WKCH@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
NFPJHIIC_00909	657322.FPR_23930	0.0	1631.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WRX8@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	lacZ	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFPJHIIC_00910	657322.FPR_23920	1.48e-123	353.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia,3WQFN@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00911	699218.HMPREF0889_1470	3.43e-17	80.5	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4H41Y@909932|Negativicutes	909932|Negativicutes	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
NFPJHIIC_00912	657322.FPR_23900	2.44e-136	389.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NFPJHIIC_00913	657322.FPR_28830	1.1e-297	815.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_00914	748224.HMPREF9436_01428	9.04e-99	291.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WG7F@541000|Ruminococcaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NFPJHIIC_00917	657322.FPR_28790	3.68e-119	341.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,3WIP4@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
NFPJHIIC_00918	657322.FPR_28780	5.1e-121	347.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,3WJQS@541000|Ruminococcaceae	186801|Clostridia	P	Chromate transporter	chrA2	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NFPJHIIC_00919	657322.FPR_28770	1.92e-120	345.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,3WJQU@541000|Ruminococcaceae	186801|Clostridia	P	Chromate transporter	chrA1	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NFPJHIIC_00920	657322.FPR_28760	2.15e-181	504.0	COG3884@1|root,COG3884@2|Bacteria,1VGWN@1239|Firmicutes,24S03@186801|Clostridia,3WM1V@541000|Ruminococcaceae	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
NFPJHIIC_00921	657322.FPR_28750	4.14e-107	318.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WH4E@541000|Ruminococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NFPJHIIC_00922	657322.FPR_15030	0.0	2270.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NFPJHIIC_00923	657322.FPR_15040	6.29e-141	397.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WIEP@541000|Ruminococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NFPJHIIC_00925	657322.FPR_15060	7.69e-142	404.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,3WGU5@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
NFPJHIIC_00926	657322.FPR_02410	0.0	1311.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,3WSBH@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
NFPJHIIC_00927	411483.FAEPRAA2165_02932	2.03e-126	363.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,3WJ04@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
NFPJHIIC_00928	748224.HMPREF9436_02532	3.2e-44	145.0	2BACE@1|root,323SU@2|Bacteria,1UH7E@1239|Firmicutes,257YA@186801|Clostridia,3WKG9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00929	657322.FPR_02440	0.0	1207.0	COG0286@1|root,COG0286@2|Bacteria,1V60T@1239|Firmicutes,24I05@186801|Clostridia,3WMIZ@541000|Ruminococcaceae	186801|Clostridia	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00930	748224.HMPREF9436_00251	4.8e-26	100.0	2EFE1@1|root,3396U@2|Bacteria,1VK14@1239|Firmicutes,253R2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00932	657322.FPR_10470	3.38e-273	748.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,3WJ3G@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
NFPJHIIC_00933	657322.FPR_10480	4.02e-158	442.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NFPJHIIC_00934	657322.FPR_10490	4.29e-231	637.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24AI7@186801|Clostridia,3WMXA@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFPJHIIC_00935	748224.HMPREF9436_02120	1.32e-122	355.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	rcoM2	GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02477,ko:K21696	-	-	-	-	ko00000,ko02022,ko03000	-	-	-	EAL,LytTR,Response_reg
NFPJHIIC_00936	657322.FPR_10520	5.91e-282	778.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WHK3@541000|Ruminococcaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
NFPJHIIC_00937	657322.FPR_13640	2.49e-302	826.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NFPJHIIC_00938	657322.FPR_13650	0.0	904.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
NFPJHIIC_00939	657322.FPR_13660	0.0	1285.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3WGDU@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NFPJHIIC_00940	657322.FPR_13670	2.16e-136	386.0	COG1309@1|root,COG1309@2|Bacteria,1VB8P@1239|Firmicutes,25AZM@186801|Clostridia,3WS6S@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00942	657322.FPR_13470	1.24e-43	152.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NFPJHIIC_00943	411483.FAEPRAA2165_00713	2.35e-47	152.0	29GWS@1|root,303UH@2|Bacteria,1TV9P@1239|Firmicutes,25A3V@186801|Clostridia,3WR4T@541000|Ruminococcaceae	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
NFPJHIIC_00944	657322.FPR_13450	1.03e-111	321.0	2E0RM@1|root,335S7@2|Bacteria,1VJ0P@1239|Firmicutes,24T08@186801|Clostridia,3WMKS@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
NFPJHIIC_00945	657322.FPR_13440	1.63e-177	494.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NFPJHIIC_00946	657322.FPR_13430	2.72e-56	175.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
NFPJHIIC_00947	657322.FPR_13420	1.75e-99	290.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24IT1@186801|Clostridia,3WS1Z@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NFPJHIIC_00948	657322.FPR_13410	8.65e-119	340.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NFPJHIIC_00949	657322.FPR_13400	0.0	968.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
NFPJHIIC_00950	657322.FPR_13390	7.99e-191	531.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NFPJHIIC_00951	748224.HMPREF9436_00325	5.68e-184	522.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3WNHD@541000|Ruminococcaceae	186801|Clostridia	O	peptidylprolyl isomerase	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
NFPJHIIC_00952	657322.FPR_11880	5.26e-280	765.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3WG9F@541000|Ruminococcaceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
NFPJHIIC_00953	657322.FPR_11890	6.69e-202	558.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NFPJHIIC_00954	657322.FPR_11900	1.43e-124	355.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3WI2S@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NFPJHIIC_00955	657322.FPR_11910	1.14e-83	247.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WK31@541000|Ruminococcaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NFPJHIIC_00956	657322.FPR_11920	3.95e-273	748.0	COG2199@1|root,COG2199@2|Bacteria,1V2R7@1239|Firmicutes,24GA5@186801|Clostridia,3WKMH@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFPJHIIC_00958	657322.FPR_24420	1.49e-251	690.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WGBA@541000|Ruminococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
NFPJHIIC_00959	657322.FPR_24410	5.81e-251	690.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
NFPJHIIC_00960	657322.FPR_24400	2.2e-273	748.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
NFPJHIIC_00961	657322.FPR_24390	1.63e-133	382.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NFPJHIIC_00962	657322.FPR_05350	1.06e-255	704.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3WIJX@541000|Ruminococcaceae	186801|Clostridia	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
NFPJHIIC_00963	411483.FAEPRAA2165_01265	2.03e-100	293.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,3WKCP@541000|Ruminococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
NFPJHIIC_00964	657322.FPR_05330	1.09e-253	694.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
NFPJHIIC_00965	657322.FPR_05320	7.3e-111	319.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3WJ9J@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
NFPJHIIC_00966	657322.FPR_05310	2.41e-234	644.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WHWT@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
NFPJHIIC_00967	657322.FPR_05300	8.64e-225	619.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NFPJHIIC_00968	657322.FPR_05290	4.23e-176	494.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3WISF@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
NFPJHIIC_00969	657322.FPR_02040	1.81e-214	600.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia,3WI0S@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
NFPJHIIC_00970	657322.FPR_02050	3.48e-294	800.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia,3WH3B@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
NFPJHIIC_00971	657322.FPR_02060	8.26e-154	435.0	COG0739@1|root,COG0739@2|Bacteria,1V7NW@1239|Firmicutes,24K65@186801|Clostridia	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NFPJHIIC_00972	657322.FPR_02070	3.68e-247	683.0	COG2271@1|root,COG2271@2|Bacteria,1TQZE@1239|Firmicutes,25E40@186801|Clostridia,3WP80@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFPJHIIC_00973	657322.FPR_02080	1.39e-148	418.0	COG1309@1|root,COG1309@2|Bacteria,1TWE4@1239|Firmicutes,24C3H@186801|Clostridia,3WM9Z@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFPJHIIC_00975	657322.FPR_20720	4.32e-118	354.0	COG1316@1|root,COG4223@1|root,COG1316@2|Bacteria,COG4223@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,3WJ6Y@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_PPF,LytR_cpsA_psr,NMT1
NFPJHIIC_00976	657322.FPR_20730	1.48e-217	600.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NFPJHIIC_00977	748224.HMPREF9436_00932	3.44e-304	847.0	COG3583@1|root,COG4942@1|root,COG3583@2|Bacteria,COG4942@2|Bacteria,1UK5Q@1239|Firmicutes,25FKW@186801|Clostridia	186801|Clostridia	D	G5	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
NFPJHIIC_00978	657322.FPR_20750	1.01e-167	469.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3WHNA@541000|Ruminococcaceae	186801|Clostridia	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NFPJHIIC_00979	657322.FPR_20760	1.3e-99	289.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
NFPJHIIC_00981	657322.FPR_07590	1.26e-157	443.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3WGU7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NFPJHIIC_00982	657322.FPR_07580	1.34e-154	434.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NFPJHIIC_00983	657322.FPR_07570	0.0	939.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NFPJHIIC_00985	397290.C810_02915	1.66e-78	245.0	2E8K9@1|root,332XY@2|Bacteria,1VDJS@1239|Firmicutes,24PSM@186801|Clostridia,27QST@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00986	1235792.C808_03987	5.01e-42	147.0	2FFQ3@1|root,347ME@2|Bacteria,1W137@1239|Firmicutes,252VZ@186801|Clostridia,27S9G@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00987	552398.HMPREF0866_00157	1.56e-48	166.0	2DJT4@1|root,32UDS@2|Bacteria,1VDA1@1239|Firmicutes,24SD3@186801|Clostridia,3WK3G@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_00988	1235792.C808_03985	1.25e-143	416.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,27JY6@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFPJHIIC_00989	552398.HMPREF0866_00159	6.58e-169	478.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFPJHIIC_00990	397290.C810_02909	7.37e-163	462.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,27KJ7@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10234	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
NFPJHIIC_00991	657322.FPR_20500	1.25e-67	205.0	COG3668@1|root,COG3668@2|Bacteria,1VA8N@1239|Firmicutes,24NW1@186801|Clostridia,3WKMP@541000|Ruminococcaceae	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
NFPJHIIC_00992	657322.FPR_20510	0.0	1022.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WHCF@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFPJHIIC_00993	657322.FPR_16110	9.2e-268	732.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
NFPJHIIC_00994	657322.FPR_16120	4.41e-155	436.0	COG0670@1|root,COG0670@2|Bacteria,1V6E1@1239|Firmicutes,25CU4@186801|Clostridia,3WSEF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
NFPJHIIC_00995	657322.FPR_16130	2.21e-192	535.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,3WJ0Q@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFPJHIIC_00996	657322.FPR_13710	0.0	1020.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WRQU@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NFPJHIIC_00997	657322.FPR_13720	0.0	873.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGRQ@541000|Ruminococcaceae	186801|Clostridia	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
NFPJHIIC_00998	657322.FPR_13730	2.04e-273	749.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
NFPJHIIC_00999	657322.FPR_21330	2.33e-300	822.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFPJHIIC_01000	657322.FPR_21340	0.0	1086.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1V4RJ@1239|Firmicutes,24IFN@186801|Clostridia,3WGT2@541000|Ruminococcaceae	186801|Clostridia	KLT	PASTA domain protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NFPJHIIC_01001	657322.FPR_21350	0.0	1009.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NFPJHIIC_01002	657322.FPR_21360	1.62e-235	689.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NFPJHIIC_01004	657322.FPR_00390	4.44e-293	832.0	COG4591@1|root,COG4591@2|Bacteria,1UJX6@1239|Firmicutes,24A96@186801|Clostridia	186801|Clostridia	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFPJHIIC_01005	657322.FPR_00400	9.81e-106	311.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFPJHIIC_01006	657322.FPR_25600	3.59e-203	562.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia,3WQ0E@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFPJHIIC_01007	657322.FPR_25590	1.28e-22	92.8	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia,3WQCH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01008	657322.FPR_29760	5.98e-83	257.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,3WGSM@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
NFPJHIIC_01009	657322.FPR_29770	3.67e-131	372.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NFPJHIIC_01010	657322.FPR_29780	0.0	1585.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WGJD@541000|Ruminococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
NFPJHIIC_01011	657322.FPR_29790	6.3e-70	212.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NFPJHIIC_01012	657322.FPR_29800	5.07e-188	521.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,2494P@186801|Clostridia	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NFPJHIIC_01013	657322.FPR_29810	1.08e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3WMCT@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4250)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
NFPJHIIC_01014	657322.FPR_30060	0.0	1294.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NFPJHIIC_01015	657322.FPR_30050	1.04e-64	197.0	COG1873@1|root,COG1873@2|Bacteria,1TUA5@1239|Firmicutes,259AT@186801|Clostridia,3WMB7@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein, YlmC YmxH family	-	-	-	-	-	-	-	-	-	-	-	-	PRC
NFPJHIIC_01016	657322.FPR_30040	7.56e-148	416.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3WKIQ@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
NFPJHIIC_01017	657322.FPR_30030	2.31e-34	117.0	291XB@1|root,2ZPGX@2|Bacteria,1W4VH@1239|Firmicutes,255C3@186801|Clostridia,3WQUH@541000|Ruminococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
NFPJHIIC_01018	657322.FPR_30020	3.55e-99	287.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3WJGD@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
NFPJHIIC_01019	718252.FP2_06210	5.68e-118	344.0	COG3503@1|root,COG3503@2|Bacteria,1V8H3@1239|Firmicutes,24JRC@186801|Clostridia,3WJIA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
NFPJHIIC_01020	657322.FPR_30000	2.88e-115	339.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3WGFB@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NFPJHIIC_01022	657322.FPR_09220	6.58e-130	369.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,3WJNN@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NFPJHIIC_01023	748224.HMPREF9436_01064	2.12e-135	386.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NFPJHIIC_01024	657322.FPR_09200	1.56e-161	452.0	COG1802@1|root,COG1802@2|Bacteria,1V90H@1239|Firmicutes,24B32@186801|Clostridia,3WQIB@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NFPJHIIC_01025	657322.FPR_09190	1.15e-123	353.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3WJ0X@541000|Ruminococcaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NFPJHIIC_01026	657322.FPR_09180	7.46e-27	108.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WGW0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NFPJHIIC_01027	657322.FPR_31190	0.0	914.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
NFPJHIIC_01030	657322.FPR_31160	1.67e-315	860.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
NFPJHIIC_01031	657322.FPR_31150	2.39e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3WI7X@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_01032	657322.FPR_08980	9.14e-130	378.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NFPJHIIC_01035	657322.FPR_08970	1.57e-157	441.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24HZR@186801|Clostridia,3WJQC@541000|Ruminococcaceae	186801|Clostridia	S	phosphoglycolate phosphatase, bacterial	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFPJHIIC_01036	657322.FPR_08960	0.0	875.0	2DVGZ@1|root,33VUK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01038	657322.FPR_08940	1.1e-158	444.0	COG0569@1|root,COG0569@2|Bacteria,1V30C@1239|Firmicutes,24GDX@186801|Clostridia,3WJ1Y@541000|Ruminococcaceae	186801|Clostridia	C	TrkA N-terminal domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NFPJHIIC_01039	657322.FPR_08930	1.07e-94	276.0	COG0569@1|root,COG0569@2|Bacteria,1V2ZF@1239|Firmicutes,24GNX@186801|Clostridia,3WIPU@541000|Ruminococcaceae	186801|Clostridia	C	TrkA N-terminal domain protein	trkA2	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
NFPJHIIC_01040	748224.HMPREF9436_00402	1.67e-224	619.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,3WJ9D@541000|Ruminococcaceae	186801|Clostridia	S	G5 domain	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
NFPJHIIC_01041	748224.HMPREF9436_00405	0.0	904.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,SLH
NFPJHIIC_01044	748224.HMPREF9436_00407	3e-89	261.0	COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia	186801|Clostridia	M	Peptidase M15A	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
NFPJHIIC_01045	748224.HMPREF9436_00408	1.2e-39	132.0	2DRAZ@1|root,33B0U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01046	748224.HMPREF9436_00409	5.45e-47	151.0	2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,24S49@186801|Clostridia,3WQWC@541000|Ruminococcaceae	186801|Clostridia	S	SPP1 phage holin	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
NFPJHIIC_01047	657322.FPR_18540	2.35e-127	361.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NFPJHIIC_01048	657322.FPR_18530	1.41e-65	207.0	COG3940@1|root,COG3940@2|Bacteria,1UK7X@1239|Firmicutes,25FPU@186801|Clostridia,3WMMK@541000|Ruminococcaceae	186801|Clostridia	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
NFPJHIIC_01049	657322.FPR_18520	3.71e-117	335.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3WJCA@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NFPJHIIC_01050	657322.FPR_18510	5.59e-119	339.0	COG0454@1|root,COG0456@2|Bacteria,1V4Y1@1239|Firmicutes,24H0B@186801|Clostridia,3WKQG@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NFPJHIIC_01051	657322.FPR_18500	3.93e-60	185.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24S4A@186801|Clostridia,3WQK5@541000|Ruminococcaceae	186801|Clostridia	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
NFPJHIIC_01052	657322.FPR_18490	7.91e-117	335.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WJ0K@541000|Ruminococcaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NFPJHIIC_01053	657322.FPR_18480	4.25e-217	598.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,3WIHT@541000|Ruminococcaceae	186801|Clostridia	Q	FAH family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
NFPJHIIC_01054	657322.FPR_19720	3.11e-90	266.0	COG0737@1|root,COG0737@2|Bacteria,1VC1M@1239|Firmicutes,24PE1@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	SLH
NFPJHIIC_01055	657322.FPR_25650	0.0	1256.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFPJHIIC_01056	657322.FPR_25670	0.0	912.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3WNFC@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFPJHIIC_01057	657322.FPR_06170	2.26e-67	210.0	COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,24DHZ@186801|Clostridia,3WRQW@541000|Ruminococcaceae	186801|Clostridia	ET	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)	-	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
NFPJHIIC_01058	657322.FPR_06160	4.06e-68	206.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3WJEP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NFPJHIIC_01059	657322.FPR_06150	2.44e-186	526.0	COG4709@1|root,COG4709@2|Bacteria,1TU53@1239|Firmicutes,24WP7@186801|Clostridia,3WKRK@541000|Ruminococcaceae	186801|Clostridia	U	Protein of unknown function (DUF1700)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NFPJHIIC_01060	657322.FPR_06140	0.0	1214.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WH2A@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
NFPJHIIC_01061	411483.FAEPRAA2165_01222	4.88e-54	169.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WK5I@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NFPJHIIC_01062	657322.FPR_06120	2.54e-195	546.0	COG0336@1|root,COG0454@1|root,COG0336@2|Bacteria,COG0456@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3WH8Z@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NFPJHIIC_01063	657322.FPR_09860	1.25e-82	243.0	COG1917@1|root,COG1917@2|Bacteria,1V7FN@1239|Firmicutes	1239|Firmicutes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NFPJHIIC_01064	657322.FPR_09870	3.41e-190	528.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3WHXZ@541000|Ruminococcaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
NFPJHIIC_01065	657322.FPR_09880	6.08e-178	496.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,3WHWH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
NFPJHIIC_01066	657322.FPR_09890	1.02e-256	703.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
NFPJHIIC_01070	657322.FPR_11930	0.0	2178.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
NFPJHIIC_01071	657322.FPR_11940	1.36e-242	665.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,3WJ0Z@541000|Ruminococcaceae	186801|Clostridia	E	Renal dipeptidase family protein	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
NFPJHIIC_01072	657322.FPR_11950	1.95e-174	487.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3WJEH@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
NFPJHIIC_01073	718252.FP2_07390	2.93e-140	397.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
NFPJHIIC_01074	657322.FPR_31270	9.41e-296	809.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NFPJHIIC_01075	657322.FPR_31260	3.34e-139	393.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3WGQP@541000|Ruminococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NFPJHIIC_01076	657322.FPR_31250	0.0	867.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NFPJHIIC_01077	657322.FPR_04810	2.46e-249	682.0	COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,2502I@186801|Clostridia,3WSPW@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFPJHIIC_01078	657322.FPR_04820	0.0	975.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,3WHMM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
NFPJHIIC_01079	748224.HMPREF9436_00158	1.6e-79	252.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24M3C@186801|Clostridia,3WPC0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 9.97	epsJ2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFPJHIIC_01080	748224.HMPREF9436_02839	6.53e-134	395.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,3WIMY@541000|Ruminococcaceae	186801|Clostridia	H	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
NFPJHIIC_01081	657322.FPR_08760	9.83e-134	380.0	2E1BB@1|root,32AJH@2|Bacteria,1V8VB@1239|Firmicutes,24K6A@186801|Clostridia,3WPQM@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
NFPJHIIC_01082	657322.FPR_08770	0.0	915.0	28JJB@1|root,2Z9CE@2|Bacteria,1UYKT@1239|Firmicutes,25DS9@186801|Clostridia,3WMYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01086	748224.HMPREF9436_00164	3.74e-69	211.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3WKMB@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
NFPJHIIC_01087	657322.FPR_11100	2.49e-180	502.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WIKF@541000|Ruminococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NFPJHIIC_01088	657322.FPR_11110	8.7e-278	761.0	2DNZ4@1|root,32ZV4@2|Bacteria,1VGWE@1239|Firmicutes,24QUP@186801|Clostridia,3WIIM@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01089	657322.FPR_11120	1.2e-130	374.0	2EFRU@1|root,339HT@2|Bacteria,1VJRN@1239|Firmicutes,24WAI@186801|Clostridia,3WMDS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
NFPJHIIC_01091	657322.FPR_09260	8.97e-20	87.4	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WHBI@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
NFPJHIIC_01093	657322.FPR_09280	6.1e-143	404.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3WJZD@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
NFPJHIIC_01094	657322.FPR_09290	1.44e-208	579.0	COG0470@1|root,COG0470@2|Bacteria,1V7FD@1239|Firmicutes,24NVX@186801|Clostridia,3WIJC@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
NFPJHIIC_01095	657322.FPR_09300	2.61e-73	224.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,3WK0Y@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
NFPJHIIC_01097	657322.FPR_19790	0.0	868.0	COG1686@1|root,COG1686@2|Bacteria,1V97N@1239|Firmicutes,24KE3@186801|Clostridia,3WRI2@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NFPJHIIC_01098	657322.FPR_19800	5.94e-176	489.0	COG1409@1|root,COG1409@2|Bacteria,1TPVN@1239|Firmicutes,24AB4@186801|Clostridia,3WSPY@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
NFPJHIIC_01099	657322.FPR_19810	7.56e-243	667.0	COG0438@1|root,COG0438@2|Bacteria,1V74B@1239|Firmicutes,2517N@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
NFPJHIIC_01100	657322.FPR_19820	3.82e-52	173.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,3WRX3@541000|Ruminococcaceae	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFPJHIIC_01101	657322.FPR_19820	5.03e-189	530.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,3WRX3@541000|Ruminococcaceae	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFPJHIIC_01102	657322.FPR_19830	1e-92	289.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NFPJHIIC_01103	657322.FPR_09380	0.0	2333.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,3WGTT@541000|Ruminococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
NFPJHIIC_01104	657322.FPR_14780	3.24e-291	798.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24Z3A@186801|Clostridia,3WMZ9@541000|Ruminococcaceae	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NFPJHIIC_01105	748224.HMPREF9436_02243	5.21e-101	307.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WHMP@541000|Ruminococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NFPJHIIC_01106	657322.FPR_14750	0.0	900.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NFPJHIIC_01107	657322.FPR_14740	3.05e-86	275.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NFPJHIIC_01108	657322.FPR_30180	9.81e-129	365.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3WJGJ@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NFPJHIIC_01109	657322.FPR_30170	0.0	1468.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NFPJHIIC_01110	657322.FPR_30160	3.48e-128	365.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NFPJHIIC_01111	657322.FPR_30150	5.98e-55	172.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
NFPJHIIC_01112	657322.FPR_30140	7.15e-199	552.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NFPJHIIC_01113	657322.FPR_05470	0.0	983.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,3WNUW@541000|Ruminococcaceae	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
NFPJHIIC_01114	657322.FPR_05480	6.35e-220	610.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
NFPJHIIC_01115	657322.FPR_05490	2.99e-149	421.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WKCU@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NFPJHIIC_01116	748224.HMPREF9436_00402	9.21e-201	560.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,3WJ9D@541000|Ruminococcaceae	186801|Clostridia	S	G5 domain	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
NFPJHIIC_01117	657322.FPR_13530	0.0	1009.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,SLH
NFPJHIIC_01118	657322.FPR_24670	3.75e-134	382.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,3WIFZ@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NFPJHIIC_01119	748224.HMPREF9436_01053	9.63e-196	545.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3WHW9@541000|Ruminococcaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NFPJHIIC_01120	657322.FPR_24700	4.69e-261	716.0	COG1589@1|root,COG1589@2|Bacteria,1UHVF@1239|Firmicutes,25E4A@186801|Clostridia,3WIXM@541000|Ruminococcaceae	186801|Clostridia	M	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
NFPJHIIC_01122	657322.FPR_24720	6.02e-250	688.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3WKX1@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
NFPJHIIC_01123	657322.FPR_04750	3.81e-151	426.0	COG1191@1|root,COG1191@2|Bacteria,1V296@1239|Firmicutes,24GTU@186801|Clostridia,3WGPV@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NFPJHIIC_01124	657322.FPR_04760	9.26e-98	284.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3WJC6@541000|Ruminococcaceae	186801|Clostridia	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
NFPJHIIC_01125	657322.FPR_04770	1.84e-65	199.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3WKRQ@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
NFPJHIIC_01126	657322.FPR_04780	9.54e-285	780.0	COG0285@1|root,COG0285@2|Bacteria	2|Bacteria	H	dihydrofolate synthase activity	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,Mur_ligase_C,Mur_ligase_M
NFPJHIIC_01127	411483.FAEPRAA2165_03500	6e-66	206.0	COG5652@1|root,COG5652@2|Bacteria,1VBNW@1239|Firmicutes,25827@186801|Clostridia,3WKKI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NFPJHIIC_01128	657322.FPR_04800	4.53e-267	752.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NFPJHIIC_01129	657322.FPR_17940	1.31e-245	676.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3WI1X@541000|Ruminococcaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
NFPJHIIC_01130	657322.FPR_17950	1.51e-118	342.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3WJK5@541000|Ruminococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NFPJHIIC_01131	657322.FPR_17960	0.0	1141.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NFPJHIIC_01132	657322.FPR_14730	6.55e-102	296.0	2EI49@1|root,33BVM@2|Bacteria,1UKGE@1239|Firmicutes,24UMT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01133	657322.FPR_14720	3.99e-231	636.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WH07@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NFPJHIIC_01134	411471.SUBVAR_05613	5.84e-47	155.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
NFPJHIIC_01135	657322.FPR_14700	2.81e-75	228.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3WK11@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01136	657322.FPR_14690	1.59e-129	368.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WJC4@541000|Ruminococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
NFPJHIIC_01137	657322.FPR_12250	7.57e-197	547.0	COG0847@1|root,COG0847@2|Bacteria,1UK7S@1239|Firmicutes,25FPM@186801|Clostridia,3WSNQ@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
NFPJHIIC_01138	657322.FPR_12260	2.23e-157	441.0	COG0398@1|root,COG0398@2|Bacteria,1V7VE@1239|Firmicutes,24NGJ@186801|Clostridia	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
NFPJHIIC_01139	657322.FPR_12270	1.12e-219	607.0	COG0544@1|root,COG0544@2|Bacteria	2|Bacteria	D	peptidyl-prolyl cis-trans isomerase activity	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NFPJHIIC_01142	748224.HMPREF9436_00095	1.18e-173	486.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NFPJHIIC_01143	657322.FPR_11270	2e-301	823.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL,WD40
NFPJHIIC_01144	657322.FPR_11280	1.81e-128	365.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,24HEU@186801|Clostridia,3WJ3B@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0340 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF436
NFPJHIIC_01145	657322.FPR_11290	1.55e-162	456.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WGKD@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NFPJHIIC_01146	657322.FPR_11300	0.0	1153.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFPJHIIC_01147	657322.FPR_25950	0.0	976.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
NFPJHIIC_01148	657322.FPR_25940	3.31e-103	300.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NFPJHIIC_01149	657322.FPR_25920	3.25e-107	309.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NFPJHIIC_01151	657322.FPR_16210	6.02e-53	174.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHCD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NFPJHIIC_01152	657322.FPR_16220	6.97e-157	439.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3WJHA@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFPJHIIC_01154	657322.FPR_16260	1.08e-101	295.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3WIJW@541000|Ruminococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NFPJHIIC_01155	657322.FPR_26130	6.08e-230	634.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3WIE9@541000|Ruminococcaceae	186801|Clostridia	D	Stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NFPJHIIC_01156	748224.HMPREF9436_03164	4.69e-161	459.0	2DW9C@1|root,33Z5T@2|Bacteria,1VBX0@1239|Firmicutes,24Q8T@186801|Clostridia,3WQE2@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01157	718252.FP2_32150	2.72e-14	74.7	COG2755@1|root,COG2755@2|Bacteria,1UM8B@1239|Firmicutes,25GBV@186801|Clostridia,3WRMU@541000|Ruminococcaceae	186801|Clostridia	E	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
NFPJHIIC_01158	657322.FPR_26100	4.46e-193	536.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NFPJHIIC_01159	657322.FPR_26200	7.18e-233	640.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,3WIK6@541000|Ruminococcaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFPJHIIC_01160	657322.FPR_26190	0.0	1305.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
NFPJHIIC_01161	657322.FPR_26180	1.6e-243	674.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WGDW@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NFPJHIIC_01162	657322.FPR_12110	8.86e-210	579.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,3WJ88@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NFPJHIIC_01163	657322.FPR_12100	2.02e-52	165.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,3WKXC@541000|Ruminococcaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NFPJHIIC_01164	657322.FPR_12090	3.59e-150	424.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
NFPJHIIC_01165	748224.HMPREF9436_01715	1.43e-44	147.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
NFPJHIIC_01166	657322.FPR_12060	1.49e-97	283.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WJN5@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NFPJHIIC_01168	748224.HMPREF9436_00613	4.52e-250	693.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,3WGB4@541000|Ruminococcaceae	186801|Clostridia	M	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
NFPJHIIC_01169	657322.FPR_11350	7.76e-122	348.0	2C1SC@1|root,345JP@2|Bacteria,1VZK9@1239|Firmicutes,253BJ@186801|Clostridia,3WQEZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01170	657322.FPR_11360	1.7e-208	577.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFPJHIIC_01171	657322.FPR_11370	1.61e-130	370.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WJKD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NFPJHIIC_01172	657322.FPR_29360	1.87e-30	110.0	COG1896@1|root,COG1896@2|Bacteria,1UIAE@1239|Firmicutes,25EFH@186801|Clostridia,3WSPD@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NFPJHIIC_01173	657322.FPR_29370	6.2e-129	365.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24KJU@186801|Clostridia	186801|Clostridia	M	acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
NFPJHIIC_01174	657322.FPR_29380	2.43e-265	725.0	COG0657@1|root,COG0657@2|Bacteria,1U1GT@1239|Firmicutes,24E51@186801|Clostridia,3WM2Q@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NFPJHIIC_01175	718252.FP2_18630	1.07e-225	636.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NFPJHIIC_01177	657322.FPR_25750	0.0	882.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WH5C@541000|Ruminococcaceae	186801|Clostridia	E	amino acid carrier protein	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFPJHIIC_01178	657322.FPR_25740	1.83e-296	811.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WGJC@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_01179	657322.FPR_25730	4.48e-131	371.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3WIK0@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoesterase	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NFPJHIIC_01180	411471.SUBVAR_05884	4.88e-155	437.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
NFPJHIIC_01181	657322.FPR_10180	2.4e-120	344.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,24ID8@186801|Clostridia,3WJDF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
NFPJHIIC_01182	657322.FPR_10190	4.04e-205	567.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3WGJB@541000|Ruminococcaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NFPJHIIC_01183	657322.FPR_28950	1.08e-126	364.0	COG0789@1|root,COG0789@2|Bacteria,1V6W4@1239|Firmicutes,24F6T@186801|Clostridia,3WKHZ@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	hmrR	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFPJHIIC_01184	657322.FPR_28960	7.92e-187	521.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GMY@186801|Clostridia,3WJXS@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NFPJHIIC_01187	657322.FPR_28970	0.0	1172.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,25FRJ@186801|Clostridia,3WKMI@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFPJHIIC_01188	657322.FPR_28980	4.13e-63	206.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NFPJHIIC_01189	657322.FPR_00470	6.32e-55	171.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,3WM3Z@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AbrB family	-	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
NFPJHIIC_01190	657322.FPR_00460	5.24e-231	635.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
NFPJHIIC_01191	657322.FPR_00450	2.63e-213	590.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3WGMA@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
NFPJHIIC_01192	748224.HMPREF9436_02140	1.96e-154	434.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3WIJ0@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_01193	657322.FPR_00430	9.53e-206	569.0	2DCDQ@1|root,2ZDSD@2|Bacteria,1V33B@1239|Firmicutes,25BJU@186801|Clostridia,3WMNK@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NFPJHIIC_01194	657322.FPR_31240	2.69e-78	243.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae	186801|Clostridia	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
NFPJHIIC_01195	657322.FPR_31230	0.0	1449.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3WGN7@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
NFPJHIIC_01196	657322.FPR_31220	1.83e-106	307.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
NFPJHIIC_01198	657322.FPR_31200	6.79e-118	340.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,24H1Q@186801|Clostridia,3WJ0A@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
NFPJHIIC_01199	657322.FPR_02380	9.49e-240	668.0	2DRD9@1|root,33BA4@2|Bacteria,1VQ0D@1239|Firmicutes,24UYQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01201	657322.FPR_02360	0.0	1255.0	2A4BH@1|root,30SX6@2|Bacteria,1V5JA@1239|Firmicutes,24IBE@186801|Clostridia,3WR7A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01204	657322.FPR_25840	2.96e-208	576.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3WH28@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
NFPJHIIC_01205	657322.FPR_25830	4.67e-232	639.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NFPJHIIC_01206	657322.FPR_25820	1.81e-85	252.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WJYA@541000|Ruminococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NFPJHIIC_01207	657322.FPR_25810	4.66e-252	711.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NFPJHIIC_01208	411483.FAEPRAA2165_03203	2.51e-217	617.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NFPJHIIC_01210	411483.FAEPRAA2165_03204	0.0	1300.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3WHGR@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
NFPJHIIC_01211	657322.FPR_03380	5.62e-55	172.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3WKHQ@541000|Ruminococcaceae	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01212	748224.HMPREF9436_02340	3.03e-78	239.0	COG0648@1|root,COG0648@2|Bacteria,1UZNN@1239|Firmicutes,24A1E@186801|Clostridia,3WH4K@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV	Nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NFPJHIIC_01213	657322.FPR_03920	1.81e-132	375.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3WGN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NFPJHIIC_01214	657322.FPR_03930	2.91e-72	223.0	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24MNV@186801|Clostridia,3WJTE@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01215	657322.FPR_03940	1.05e-63	194.0	2DG94@1|root,337GI@2|Bacteria,1VHDH@1239|Firmicutes,24RH0@186801|Clostridia,3WKWR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01216	657322.FPR_03950	1.07e-208	577.0	COG2755@1|root,COG2755@2|Bacteria,1VCJD@1239|Firmicutes,25B7F@186801|Clostridia,3WS5V@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFPJHIIC_01217	657322.FPR_03960	2.89e-186	530.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NFPJHIIC_01218	657322.FPR_03580	1.22e-213	597.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
NFPJHIIC_01219	657322.FPR_03570	4.39e-130	371.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,3WJSP@541000|Ruminococcaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
NFPJHIIC_01220	657322.FPR_03560	3.69e-111	319.0	COG3409@1|root,COG3409@2|Bacteria,1VMBN@1239|Firmicutes,24V9S@186801|Clostridia	186801|Clostridia	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
NFPJHIIC_01221	411483.FAEPRAA2165_03180	1.31e-229	638.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NFPJHIIC_01222	657322.FPR_18470	1.75e-73	228.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHF9@541000|Ruminococcaceae	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NFPJHIIC_01223	657322.FPR_18450	0.0	1217.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NFPJHIIC_01224	657322.FPR_18440	2.51e-157	441.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3WI50@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
NFPJHIIC_01225	657322.FPR_16360	3.16e-56	181.0	COG1028@1|root,COG1028@2|Bacteria,1TQ3V@1239|Firmicutes,24ARQ@186801|Clostridia,3WIKB@541000|Ruminococcaceae	186801|Clostridia	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NFPJHIIC_01226	657322.FPR_16370	7.66e-221	615.0	COG3206@1|root,COG3206@2|Bacteria,1V8AX@1239|Firmicutes,25EXZ@186801|Clostridia,3WJXV@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
NFPJHIIC_01227	657322.FPR_16380	3.63e-115	330.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24MBJ@186801|Clostridia,3WRU8@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATPase subunit of terminase (gpP-like)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFPJHIIC_01230	657322.FPR_16410	3.61e-125	357.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3WJPD@541000|Ruminococcaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
NFPJHIIC_01231	657322.FPR_02290	0.0	1011.0	COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia,3WPQU@541000|Ruminococcaceae	186801|Clostridia	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
NFPJHIIC_01233	657322.FPR_06040	2.95e-87	259.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3WGYU@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
NFPJHIIC_01234	657322.FPR_06050	8.47e-301	822.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WHF4@541000|Ruminococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_01235	748224.HMPREF9436_02582	1.6e-171	484.0	COG0031@1|root,COG0031@2|Bacteria,1VQV3@1239|Firmicutes,24XIE@186801|Clostridia,3WP2E@541000|Ruminococcaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	PALP
NFPJHIIC_01236	657322.FPR_06070	2.82e-83	246.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3WKPX@541000|Ruminococcaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
NFPJHIIC_01237	657322.FPR_30770	1.69e-135	384.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3WJCH@541000|Ruminococcaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
NFPJHIIC_01238	657322.FPR_30780	2.45e-244	671.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3WI1B@541000|Ruminococcaceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
NFPJHIIC_01239	657322.FPR_30790	1.05e-157	443.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01240	748224.HMPREF9436_01589	1.59e-241	682.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NFPJHIIC_01241	657322.FPR_17760	4.95e-160	449.0	COG4660@1|root,COG4660@2|Bacteria,1VNRD@1239|Firmicutes,24WZ3@186801|Clostridia,3WS16@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NFPJHIIC_01242	657322.FPR_17750	1.71e-241	664.0	COG4658@1|root,COG4658@2|Bacteria,1V59Z@1239|Firmicutes,24HKP@186801|Clostridia,3WJIV@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the NqrB RnfD family	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NFPJHIIC_01243	657322.FPR_17740	8.39e-151	424.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NFPJHIIC_01244	657322.FPR_17730	2.27e-162	465.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WSMC@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFPJHIIC_01245	657322.FPR_11460	0.0	1134.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3WG7T@541000|Ruminococcaceae	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
NFPJHIIC_01246	657322.FPR_11450	1.93e-170	477.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
NFPJHIIC_01247	411483.FAEPRAA2165_02494	1.58e-120	347.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3WKA4@541000|Ruminococcaceae	186801|Clostridia	S	SAM-dependent methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
NFPJHIIC_01248	657322.FPR_28070	1.81e-139	393.0	COG1573@1|root,COG1573@2|Bacteria,1V267@1239|Firmicutes,24DFW@186801|Clostridia,3WIGX@541000|Ruminococcaceae	186801|Clostridia	L	Uracil-DNA glycosylase	udgA	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NFPJHIIC_01249	657322.FPR_28060	8.06e-258	707.0	COG1474@1|root,COG1474@2|Bacteria,1UHVJ@1239|Firmicutes,25E4E@186801|Clostridia,3WGJ4@541000|Ruminococcaceae	186801|Clostridia	LO	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01250	657322.FPR_31650	9.36e-226	621.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3WHUE@541000|Ruminococcaceae	186801|Clostridia	C	pyruvate formate lyase activating	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NFPJHIIC_01252	657322.FPR_15910	3.09e-244	671.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3WGY4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
NFPJHIIC_01253	657322.FPR_15900	1.04e-123	353.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3WJ0F@541000|Ruminococcaceae	186801|Clostridia	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
NFPJHIIC_01254	657322.FPR_15890	0.0	977.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NFPJHIIC_01255	657322.FPR_18380	3.18e-148	417.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3WIVV@541000|Ruminococcaceae	186801|Clostridia	F	Orotate phosphoribosyltransferase	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NFPJHIIC_01257	657322.FPR_17660	4.1e-152	428.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3WI24@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NFPJHIIC_01258	657322.FPR_17650	0.0	1172.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NFPJHIIC_01259	657322.FPR_17640	6.33e-46	147.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NFPJHIIC_01260	657322.FPR_17630	1.38e-71	215.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NFPJHIIC_01261	657322.FPR_13480	1.67e-273	748.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NFPJHIIC_01262	657322.FPR_13490	7.98e-258	710.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NFPJHIIC_01263	657322.FPR_13510	1.35e-248	697.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NFPJHIIC_01264	657322.FPR_02810	1.58e-142	402.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247VU@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
NFPJHIIC_01266	748224.HMPREF9436_02515	1.74e-212	591.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	CinA,MoCF_biosynth,Sortase,SpoIID
NFPJHIIC_01267	748224.HMPREF9436_00723	4.99e-180	502.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,3WJP7@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NFPJHIIC_01268	411483.FAEPRAA2165_01193	2.44e-245	674.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,3WK7V@541000|Ruminococcaceae	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFPJHIIC_01269	748224.HMPREF9436_00720	3.23e-121	347.0	COG3090@1|root,COG3090@2|Bacteria,1V3SM@1239|Firmicutes,24AP0@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFPJHIIC_01270	411483.FAEPRAA2165_01191	1.34e-281	773.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFPJHIIC_01271	657322.FPR_11050	5.79e-78	240.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3WGXE@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NFPJHIIC_01272	657322.FPR_11060	5.86e-227	623.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NFPJHIIC_01273	657322.FPR_11070	1.69e-195	542.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG9K@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NFPJHIIC_01274	657322.FPR_11080	1.31e-216	598.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG8V@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	cbiO	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NFPJHIIC_01275	657322.FPR_06000	5.29e-282	771.0	2DF4U@1|root,2ZQGY@2|Bacteria,1UFDY@1239|Firmicutes,251JV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01276	657322.FPR_06010	7.15e-95	276.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WK7G@541000|Ruminococcaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NFPJHIIC_01277	657322.FPR_06020	6.81e-160	449.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
NFPJHIIC_01278	657322.FPR_06030	1.79e-105	304.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WJA1@541000|Ruminococcaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NFPJHIIC_01279	657322.FPR_19850	0.0	1134.0	COG0187@1|root,COG0187@2|Bacteria,1TQ6U@1239|Firmicutes,249NI@186801|Clostridia,3WH8Y@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NFPJHIIC_01280	657322.FPR_26320	9.76e-195	553.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NFPJHIIC_01281	657322.FPR_26330	1.25e-208	577.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NFPJHIIC_01282	657322.FPR_26340	0.0	912.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NFPJHIIC_01283	657322.FPR_26350	4.73e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3WJYM@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
NFPJHIIC_01284	657322.FPR_20520	3.26e-106	306.0	COG2731@1|root,COG2731@2|Bacteria,1VFU3@1239|Firmicutes,24JDR@186801|Clostridia,3WQG1@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
NFPJHIIC_01286	657322.FPR_20540	2.76e-208	582.0	COG3290@1|root,COG3290@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3WIB6@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFPJHIIC_01287	657322.FPR_20560	5.51e-172	480.0	COG3279@1|root,COG3279@2|Bacteria,1VEBW@1239|Firmicutes,24NE6@186801|Clostridia,3WM2U@541000|Ruminococcaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFPJHIIC_01288	411483.FAEPRAA2165_01030	9.32e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,3WIQ8@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_01289	411483.FAEPRAA2165_01031	3.32e-212	587.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3WGJ6@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	bcrA_2	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
NFPJHIIC_01290	657322.FPR_26370	1.05e-174	487.0	COG4200@1|root,COG4200@2|Bacteria,1V273@1239|Firmicutes,24HVF@186801|Clostridia,3WKNS@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NFPJHIIC_01291	657322.FPR_26030	4.83e-163	456.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFPJHIIC_01292	657322.FPR_26040	3.15e-255	700.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
NFPJHIIC_01293	657322.FPR_26050	2.79e-177	494.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
NFPJHIIC_01295	657322.FPR_21710	1.45e-233	643.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WHIU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFPJHIIC_01296	657322.FPR_21720	9.45e-198	548.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,248PG@186801|Clostridia,3WRIK@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFPJHIIC_01297	657322.FPR_21730	6.98e-104	300.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3WJQ9@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
NFPJHIIC_01298	657322.FPR_21740	1.3e-77	246.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WH1A@541000|Ruminococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
NFPJHIIC_01299	657322.FPR_12640	1.43e-230	636.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3WHKQ@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NFPJHIIC_01300	657322.FPR_12650	3.12e-193	538.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3WGTF@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NFPJHIIC_01301	657322.FPR_12660	3.93e-218	606.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport systems periplasmic component	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
NFPJHIIC_01302	657322.FPR_08750	6.17e-29	114.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,3WPGY@541000|Ruminococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
NFPJHIIC_01303	657322.FPR_08740	3.01e-309	844.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,3WH9E@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_01304	657322.FPR_08730	3.04e-128	364.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,3WK6H@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NFPJHIIC_01306	657322.FPR_08710	4.34e-213	589.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,3WRR7@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFPJHIIC_01307	657322.FPR_03610	2.97e-119	349.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WGAJ@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
NFPJHIIC_01308	657322.FPR_03620	6.13e-201	557.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WH6J@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NFPJHIIC_01309	411483.FAEPRAA2165_03172	7.8e-31	109.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,3WKT4@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
NFPJHIIC_01310	657322.FPR_03640	2.08e-159	446.0	2DWX0@1|root,342AY@2|Bacteria,1UBPC@1239|Firmicutes,259A2@186801|Clostridia,3WPTT@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01311	657322.FPR_03650	3.5e-64	196.0	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes,24V04@186801|Clostridia,3WMSX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NFPJHIIC_01312	657322.FPR_17570	0.0	1019.0	COG0040@1|root,COG3705@1|root,COG0040@2|Bacteria,COG3705@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3WH70@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
NFPJHIIC_01313	657322.FPR_17580	1.51e-85	253.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3WGSZ@541000|Ruminococcaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
NFPJHIIC_01314	657322.FPR_17590	1.98e-87	258.0	COG1846@1|root,COG1846@2|Bacteria,1V6UN@1239|Firmicutes,24JGS@186801|Clostridia,3WIVE@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
NFPJHIIC_01315	657322.FPR_05840	0.0	987.0	COG2217@1|root,COG2217@2|Bacteria,1UZUH@1239|Firmicutes,24DMV@186801|Clostridia,3WGP6@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01316	748224.HMPREF9436_01850	1.66e-280	773.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WHK6@541000|Ruminococcaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFPJHIIC_01317	411483.FAEPRAA2165_00647	8.62e-70	221.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3WGUY@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
NFPJHIIC_01318	657322.FPR_29440	0.0	921.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
NFPJHIIC_01319	748224.HMPREF9436_02966	1.54e-130	376.0	2BBZZ@1|root,325IJ@2|Bacteria,1URJQ@1239|Firmicutes,259G0@186801|Clostridia,3WQ3T@541000|Ruminococcaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
NFPJHIIC_01320	657322.FPR_09980	7.26e-115	329.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia,3WJW3@541000|Ruminococcaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFPJHIIC_01321	657322.FPR_09970	2.87e-83	246.0	COG2169@1|root,COG2169@2|Bacteria,1UK9A@1239|Firmicutes,25FR9@186801|Clostridia,3WS6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFPJHIIC_01322	657322.FPR_09960	1.22e-146	414.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WIXN@541000|Ruminococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NFPJHIIC_01323	657322.FPR_09950	6.61e-181	503.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WGH2@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
NFPJHIIC_01324	657322.FPR_09940	5.1e-67	210.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3WGN2@541000|Ruminococcaceae	186801|Clostridia	P	phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NFPJHIIC_01325	657322.FPR_11970	1.14e-83	247.0	COG1266@1|root,COG1266@2|Bacteria,1VKW2@1239|Firmicutes,24QJG@186801|Clostridia,3WM89@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NFPJHIIC_01326	657322.FPR_11980	3.77e-118	337.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WJHQ@541000|Ruminococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
NFPJHIIC_01327	748224.HMPREF9436_00309	7.73e-149	429.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,3WIP8@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
NFPJHIIC_01328	657322.FPR_10160	1.8e-246	687.0	COG0583@1|root,COG2365@1|root,COG0583@2|Bacteria,COG2365@2|Bacteria,1V851@1239|Firmicutes,24P75@186801|Clostridia,3WM6J@541000|Ruminococcaceae	186801|Clostridia	K	Pfam:Y_phosphatase3C	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	HTH_1,LysR_substrate,Y_phosphatase3
NFPJHIIC_01329	657322.FPR_10150	0.0	1354.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3WGSN@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,PUD
NFPJHIIC_01330	748224.HMPREF9436_01971	4.54e-66	206.0	2ERJG@1|root,33J4Z@2|Bacteria,1VMR6@1239|Firmicutes,25P9S@186801|Clostridia,3WQ0K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01332	657322.FPR_10990	3.61e-34	117.0	2CHQ1@1|root,32YKW@2|Bacteria,1VG7A@1239|Firmicutes,24RG3@186801|Clostridia,3WKVF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01333	657322.FPR_10980	1.45e-93	273.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3WMN1@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
NFPJHIIC_01334	657322.FPR_10970	0.0	1023.0	COG3675@1|root,COG3675@2|Bacteria,1VCNZ@1239|Firmicutes,24U5I@186801|Clostridia,3WQ4X@541000|Ruminococcaceae	186801|Clostridia	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
NFPJHIIC_01335	657322.FPR_19880	5.86e-191	531.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NFPJHIIC_01336	657322.FPR_19890	0.0	1395.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WSRM@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NFPJHIIC_01337	718252.FP2_19460	4.01e-108	322.0	COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter	-	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
NFPJHIIC_01338	748224.HMPREF9436_03158	1.06e-201	559.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WI95@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
NFPJHIIC_01339	748224.HMPREF9436_03159	2.72e-206	571.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WHFG@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
NFPJHIIC_01340	657322.FPR_27520	1.13e-32	113.0	2E6GH@1|root,3313R@2|Bacteria,1VJ41@1239|Firmicutes,24S7U@186801|Clostridia,3WMQ0@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01341	657322.FPR_09370	2.31e-151	429.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3WHA4@541000|Ruminococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
NFPJHIIC_01342	657322.FPR_09360	8.06e-17	73.2	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3WMHU@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NFPJHIIC_01343	657322.FPR_09350	3.26e-156	438.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3WH2K@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
NFPJHIIC_01344	657322.FPR_09340	1.13e-190	530.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3WGFD@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NFPJHIIC_01345	748224.HMPREF9436_00200	1.21e-83	250.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3WM2W@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NFPJHIIC_01346	657322.FPR_10060	6.84e-82	254.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3WIV4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NFPJHIIC_01347	657322.FPR_10070	0.0	1761.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,3WSRG@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg
NFPJHIIC_01348	657322.FPR_24350	9.72e-166	464.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,3WGU3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
NFPJHIIC_01349	657322.FPR_24360	6.61e-167	466.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3WGUN@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NFPJHIIC_01350	657322.FPR_24370	1.04e-117	338.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
NFPJHIIC_01351	657322.FPR_24380	1.98e-173	483.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3WGF5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NFPJHIIC_01352	657322.FPR_18430	1.37e-151	431.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3WGDG@541000|Ruminococcaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NFPJHIIC_01353	657322.FPR_18420	1.07e-191	531.0	COG2819@1|root,COG2819@2|Bacteria,1UY7T@1239|Firmicutes,25BJ8@186801|Clostridia	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NFPJHIIC_01354	657322.FPR_18410	1.41e-203	560.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,2494P@186801|Clostridia,3WJ6V@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NFPJHIIC_01355	657322.FPR_02090	6.82e-44	153.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NFPJHIIC_01356	657322.FPR_02100	4.98e-146	412.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
NFPJHIIC_01357	657322.FPR_02110	4.92e-148	416.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WS6N@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NFPJHIIC_01359	657322.FPR_15490	0.0	1030.0	COG1203@1|root,COG1203@2|Bacteria,1TSVP@1239|Firmicutes,24C2Z@186801|Clostridia	186801|Clostridia	L	CRISPR system CASCADE complex protein CasA	casA	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
NFPJHIIC_01360	657322.FPR_15500	1.78e-146	412.0	2DP12@1|root,33037@2|Bacteria,1UIAU@1239|Firmicutes,25EFZ@186801|Clostridia,3WQ1R@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
NFPJHIIC_01361	657322.FPR_15510	5.49e-240	661.0	COG1857@1|root,COG1857@2|Bacteria,1TSM0@1239|Firmicutes,24DJI@186801|Clostridia	186801|Clostridia	L	CRISPR system CASCADE complex protein CasC	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
NFPJHIIC_01362	657322.FPR_31540	6.75e-92	268.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WKYJ@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NFPJHIIC_01363	657322.FPR_31550	2.02e-308	840.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NFPJHIIC_01364	657322.FPR_31560	2.14e-164	459.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
NFPJHIIC_01365	411483.FAEPRAA2165_00254	1e-114	332.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NFPJHIIC_01366	657322.FPR_09140	7.54e-44	142.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3WKWG@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NFPJHIIC_01367	657322.FPR_09150	6.41e-261	716.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WHXU@541000|Ruminococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NFPJHIIC_01368	657322.FPR_09160	1.47e-54	170.0	2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,24MQP@186801|Clostridia,3WKJK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	-	-	-	-	-	-	-	-	-	-	-	-	DUF370
NFPJHIIC_01369	680646.RMDY18_00050	1.88e-16	90.1	2DXS1@1|root,32V40@2|Bacteria,2HAC0@201174|Actinobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01370	657322.FPR_12040	6.1e-228	627.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3WGRE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NFPJHIIC_01371	411483.FAEPRAA2165_03465	7.23e-51	160.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3WJXE@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
NFPJHIIC_01372	657322.FPR_12020	9.55e-88	258.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,3WKK1@541000|Ruminococcaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
NFPJHIIC_01373	657322.FPR_12010	1.25e-74	223.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NFPJHIIC_01374	657322.FPR_12000	1.31e-150	433.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NFPJHIIC_01375	748224.HMPREF9436_02838	7.03e-156	436.0	COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia,3WJ7K@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
NFPJHIIC_01376	748224.HMPREF9436_02839	0.0	1140.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,3WIMY@541000|Ruminococcaceae	186801|Clostridia	H	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
NFPJHIIC_01377	657322.FPR_05200	4.62e-188	523.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia,3WMR7@541000|Ruminococcaceae	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NFPJHIIC_01378	657322.FPR_05190	1.05e-49	158.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
NFPJHIIC_01379	748224.HMPREF9436_00471	7.3e-99	289.0	2BDCF@1|root,32717@2|Bacteria,1USX3@1239|Firmicutes,25040@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01381	748224.HMPREF9436_02567	5.48e-206	576.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WGZG@541000|Ruminococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NFPJHIIC_01382	657322.FPR_06210	6.68e-195	540.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3WM3U@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NFPJHIIC_01383	657322.FPR_10090	5.82e-190	529.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
NFPJHIIC_01384	748224.HMPREF9436_02129	9.52e-145	410.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,3WISN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
NFPJHIIC_01385	657322.FPR_10110	1.36e-241	663.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,24AVD@186801|Clostridia,3WRII@541000|Ruminococcaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
NFPJHIIC_01386	657322.FPR_26310	2.61e-94	277.0	COG0711@1|root,COG0711@2|Bacteria,1VEI8@1239|Firmicutes	1239|Firmicutes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NFPJHIIC_01387	657322.FPR_26300	2.19e-38	129.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WKSD@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
NFPJHIIC_01388	657322.FPR_26290	1.95e-150	424.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3WIAV@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NFPJHIIC_01389	657322.FPR_26270	5.47e-103	298.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3WK7E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NFPJHIIC_01390	657322.FPR_31710	3.96e-195	542.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NFPJHIIC_01391	657322.FPR_31700	1.63e-174	486.0	COG0727@1|root,COG0727@2|Bacteria,1V0FA@1239|Firmicutes,24CDU@186801|Clostridia,3WKMK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NFPJHIIC_01392	657322.FPR_23880	3.16e-46	149.0	COG1314@1|root,COG1314@2|Bacteria,1VP2Z@1239|Firmicutes,24UWV@186801|Clostridia	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
NFPJHIIC_01393	657322.FPR_23870	0.0	980.0	COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,25CAC@186801|Clostridia,3WI5D@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NFPJHIIC_01395	657322.FPR_11250	6.63e-163	456.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3WGIQ@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFPJHIIC_01396	657322.FPR_02910	2.81e-36	123.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NFPJHIIC_01397	657322.FPR_02900	9.62e-142	399.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3WJ9N@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
NFPJHIIC_01398	657322.FPR_02890	1.15e-134	382.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,24FY8@186801|Clostridia,3WK6K@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PRK
NFPJHIIC_01399	748224.HMPREF9436_02509	3.45e-194	541.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02615	GDP_Man_Dehyd
NFPJHIIC_01400	657322.FPR_01340	2.92e-232	639.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFPJHIIC_01401	657322.FPR_01350	9.46e-298	814.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFPJHIIC_01402	411483.FAEPRAA2165_00348	3.1e-09	56.6	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
NFPJHIIC_01403	657322.FPR_02130	8.49e-125	356.0	COG2246@1|root,COG2246@2|Bacteria,1TTFB@1239|Firmicutes,258CB@186801|Clostridia,3WMEE@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
NFPJHIIC_01405	657322.FPR_02150	4.67e-155	435.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
NFPJHIIC_01406	657322.FPR_02160	1.94e-16	79.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,251V9@186801|Clostridia,3WJ37@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFPJHIIC_01407	748224.HMPREF9436_00427	0.0	936.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
NFPJHIIC_01408	748224.HMPREF9436_00425	1.79e-173	484.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia,3WM22@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFPJHIIC_01409	657322.FPR_00940	1.58e-117	347.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3WHPN@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
NFPJHIIC_01410	657322.FPR_00950	6.35e-276	756.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NFPJHIIC_01412	657322.FPR_16880	1.12e-216	598.0	COG1266@1|root,COG1266@2|Bacteria,1V416@1239|Firmicutes,24MKP@186801|Clostridia,3WMQU@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NFPJHIIC_01413	657322.FPR_16870	5.4e-63	193.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3WJX0@541000|Ruminococcaceae	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
NFPJHIIC_01414	657322.FPR_16860	4.63e-144	407.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3WKBG@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFPJHIIC_01415	657322.FPR_16850	5.89e-205	571.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3WGD9@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
NFPJHIIC_01416	657322.FPR_05000	1.39e-120	354.0	COG3581@1|root,COG3581@2|Bacteria,1TRVV@1239|Firmicutes,24947@186801|Clostridia,3WH15@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NFPJHIIC_01417	657322.FPR_04990	2.78e-218	602.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes	1239|Firmicutes	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01418	657322.FPR_29020	4.15e-298	813.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3WGJ7@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
NFPJHIIC_01419	657322.FPR_29030	3.12e-115	330.0	COG2954@1|root,COG2954@2|Bacteria,1VJMJ@1239|Firmicutes,257RA@186801|Clostridia,3WJIX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01420	748224.HMPREF9436_01440	2.43e-108	315.0	COG0705@1|root,COG0705@2|Bacteria,1V1C3@1239|Firmicutes,24GPR@186801|Clostridia,3WJQT@541000|Ruminococcaceae	186801|Clostridia	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
NFPJHIIC_01422	657322.FPR_28300	3.59e-21	83.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3WMB3@541000|Ruminococcaceae	186801|Clostridia	S	RSAM-modified six-cysteine peptide	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
NFPJHIIC_01425	748224.HMPREF9436_01606	1.93e-78	249.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	ushA	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
NFPJHIIC_01426	411483.FAEPRAA2165_00432	2.36e-246	682.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3WHZ5@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFPJHIIC_01427	657322.FPR_03370	3.08e-302	827.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WG82@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
NFPJHIIC_01428	411483.FAEPRAA2165_02501	5.42e-160	462.0	COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,24826@186801|Clostridia,3WHF1@541000|Ruminococcaceae	186801|Clostridia	T	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
NFPJHIIC_01429	657322.FPR_11410	3.27e-150	424.0	COG0347@1|root,COG0347@2|Bacteria,1V20Y@1239|Firmicutes,24G40@186801|Clostridia,3WKCD@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
NFPJHIIC_01430	657322.FPR_11420	5.63e-196	545.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,3WSC6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NFPJHIIC_01431	657322.FPR_11430	4.95e-57	176.0	COG1251@1|root,COG1251@2|Bacteria,1W1DD@1239|Firmicutes,25EHF@186801|Clostridia,3WSM6@541000|Ruminococcaceae	186801|Clostridia	C	Hydrid cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
NFPJHIIC_01432	657322.FPR_05500	1.82e-115	337.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3WHGJ@541000|Ruminococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFPJHIIC_01433	657322.FPR_05510	1.37e-141	399.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NFPJHIIC_01434	657322.FPR_05520	7.7e-111	320.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3WK3X@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
NFPJHIIC_01435	657322.FPR_05530	1.4e-158	444.0	COG0546@1|root,COG0546@2|Bacteria,1V7EI@1239|Firmicutes,24K0E@186801|Clostridia,3WPBF@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NFPJHIIC_01438	657322.FPR_12380	0.0	915.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NFPJHIIC_01439	657322.FPR_12390	2.76e-104	301.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WITG@541000|Ruminococcaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NFPJHIIC_01440	657322.FPR_12400	1.59e-212	591.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WG87@541000|Ruminococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NFPJHIIC_01441	657322.FPR_15630	0.0	1026.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia,3WGH9@541000|Ruminococcaceae	186801|Clostridia	C	Mannitol dehydrogenase	-	-	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NFPJHIIC_01442	657322.FPR_00500	0.0	1020.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
NFPJHIIC_01443	657322.FPR_00510	6.34e-142	399.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3WIIU@541000|Ruminococcaceae	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NFPJHIIC_01444	657322.FPR_02850	2.18e-215	594.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3WGQ3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NFPJHIIC_01445	657322.FPR_02860	2.06e-234	643.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3WGZV@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NFPJHIIC_01448	657322.FPR_18270	2.5e-236	652.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3WGJT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
NFPJHIIC_01449	657322.FPR_02230	0.0	1324.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
NFPJHIIC_01451	657322.FPR_06500	8.68e-316	859.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
NFPJHIIC_01452	657322.FPR_12160	5.95e-56	189.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFPJHIIC_01453	657322.FPR_12150	1.01e-37	135.0	COG1826@1|root,COG1826@2|Bacteria,1VHQF@1239|Firmicutes,24QW5@186801|Clostridia	186801|Clostridia	U	mttA/Hcf106 family	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
NFPJHIIC_01454	657322.FPR_12140	2.4e-33	115.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
NFPJHIIC_01455	748224.HMPREF9436_00295	5.51e-158	446.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,24KCD@186801|Clostridia	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
NFPJHIIC_01456	657322.FPR_12120	7.33e-73	237.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NFPJHIIC_01457	748224.HMPREF9436_00082	1.86e-183	513.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WGTZ@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NFPJHIIC_01458	657322.FPR_08990	1.63e-199	553.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NFPJHIIC_01459	748224.HMPREF9436_02405	2.52e-215	603.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WGHH@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
NFPJHIIC_01460	748224.HMPREF9436_02403	1.8e-191	533.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NFPJHIIC_01462	657322.FPR_15700	7.54e-211	583.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFPJHIIC_01463	657322.FPR_15690	4.65e-185	514.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
NFPJHIIC_01464	657322.FPR_29100	1.36e-143	404.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJCY@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
NFPJHIIC_01465	657322.FPR_29110	2.23e-71	214.0	COG2087@1|root,COG2087@2|Bacteria,1UQZG@1239|Firmicutes,258SR@186801|Clostridia,3WMDV@541000|Ruminococcaceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NFPJHIIC_01466	657322.FPR_29120	8.01e-175	488.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3WIUR@541000|Ruminococcaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NFPJHIIC_01467	657322.FPR_29130	2.81e-112	323.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3WK4Z@541000|Ruminococcaceae	186801|Clostridia	H	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NFPJHIIC_01469	657322.FPR_14680	5.97e-77	232.0	COG0431@1|root,COG0431@2|Bacteria,1UK51@1239|Firmicutes,25FKA@186801|Clostridia,3WN56@541000|Ruminococcaceae	186801|Clostridia	C	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFPJHIIC_01470	657322.FPR_20310	6.35e-46	148.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFPJHIIC_01471	657322.FPR_20320	3.91e-210	579.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WGGA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NFPJHIIC_01472	657322.FPR_31620	2.82e-190	528.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3WIBU@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
NFPJHIIC_01473	657322.FPR_31610	5.55e-220	608.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NFPJHIIC_01474	657322.FPR_31600	2.88e-148	421.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	dnaD	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2,HTH_36
NFPJHIIC_01475	657322.FPR_26060	1.55e-41	144.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WHNT@541000|Ruminococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
NFPJHIIC_01476	657322.FPR_26070	1.94e-186	534.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
NFPJHIIC_01478	657322.FPR_09920	1.62e-170	481.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3WIXR@541000|Ruminococcaceae	186801|Clostridia	P	Phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	Big_5,PBP_like_2
NFPJHIIC_01481	748224.HMPREF9436_02262	7.55e-48	160.0	2ES3K@1|root,33JNI@2|Bacteria,1VKAS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01482	657322.FPR_01310	2.41e-260	714.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,24DMY@186801|Clostridia,3WPF4@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFPJHIIC_01483	657322.FPR_13030	3.62e-161	462.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHD5@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NFPJHIIC_01484	657322.FPR_12360	3.41e-257	706.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia,3WJWA@541000|Ruminococcaceae	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NFPJHIIC_01485	657322.FPR_12340	2.97e-44	152.0	COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,2490M@186801|Clostridia	186801|Clostridia	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NFPJHIIC_01486	718252.FP2_31170	4.87e-22	94.0	COG1418@1|root,COG3599@1|root,COG1418@2|Bacteria,COG3599@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
NFPJHIIC_01488	657322.FPR_15570	1.62e-70	213.0	COG2198@1|root,COG2198@2|Bacteria,1TUB8@1239|Firmicutes,24W35@186801|Clostridia	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NFPJHIIC_01490	657322.FPR_15560	3.14e-157	441.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,3WJ7R@541000|Ruminococcaceae	186801|Clostridia	E	Vitamin B12 dependent methionine synthase activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
NFPJHIIC_01491	657322.FPR_29330	1.17e-115	331.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NFPJHIIC_01492	657322.FPR_29340	5.93e-190	526.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3WIZJ@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NFPJHIIC_01493	657322.FPR_29350	2.21e-100	291.0	2FDXA@1|root,345XQ@2|Bacteria,1VYRW@1239|Firmicutes,253D4@186801|Clostridia,3WQHI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01494	657322.FPR_28310	4.42e-15	73.6	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3WGAH@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NFPJHIIC_01495	657322.FPR_28320	0.0	904.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3WHCW@541000|Ruminococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	-	-	4.1.1.18,4.1.1.19	ko:K01582,ko:K01583,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	M00133	R00462,R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NFPJHIIC_01496	657322.FPR_28330	1.01e-142	403.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,249B1@186801|Clostridia	186801|Clostridia	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
NFPJHIIC_01501	657322.FPR_20400	1.1e-298	814.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NFPJHIIC_01502	657322.FPR_20390	7.48e-57	187.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NFPJHIIC_01503	657322.FPR_05890	2.62e-35	124.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3WJFT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
NFPJHIIC_01504	657322.FPR_05880	7.09e-185	515.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3WGUI@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NFPJHIIC_01505	657322.FPR_05870	6.92e-148	416.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NFPJHIIC_01506	657322.FPR_10950	2.75e-213	588.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3WJHN@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFPJHIIC_01507	657322.FPR_10940	3.69e-179	498.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3WK2R@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NFPJHIIC_01512	657322.FPR_05830	1.07e-172	485.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
NFPJHIIC_01513	411483.FAEPRAA2165_01829	6.18e-19	83.2	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NFPJHIIC_01514	657322.FPR_19910	8.28e-291	795.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3WHYK@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NFPJHIIC_01516	657322.FPR_24740	0.0	1373.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
NFPJHIIC_01517	657322.FPR_26000	0.0	864.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3WGPD@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
NFPJHIIC_01518	657322.FPR_25990	1.46e-103	308.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3WGTW@541000|Ruminococcaceae	186801|Clostridia	F	AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
NFPJHIIC_01519	657322.FPR_08700	0.0	964.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3WHDM@541000|Ruminococcaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
NFPJHIIC_01520	748224.HMPREF9436_01804	6.28e-148	440.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
NFPJHIIC_01521	748224.HMPREF9436_01702	2.65e-15	71.2	COG0847@1|root,COG0847@2|Bacteria,1V0CE@1239|Firmicutes,24AR6@186801|Clostridia,3WQ12@541000|Ruminococcaceae	186801|Clostridia	L	K02342 DNA polymerase III subunit epsilon	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978,RNase_T
NFPJHIIC_01522	748224.HMPREF9436_01700	2.98e-115	331.0	2DKU6@1|root,30BEK@2|Bacteria,1V5I4@1239|Firmicutes,24HYE@186801|Clostridia	186801|Clostridia	S	CRISPR system CASCADE complex protein CasE	casE	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
NFPJHIIC_01523	657322.FPR_20610	2.32e-301	820.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
NFPJHIIC_01524	657322.FPR_20600	6.02e-193	540.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3WGMN@541000|Ruminococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
NFPJHIIC_01525	657322.FPR_09080	1.63e-237	655.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NFPJHIIC_01526	748224.HMPREF9436_00078	3.77e-68	206.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NFPJHIIC_01527	657322.FPR_08690	2.81e-121	353.0	28JHK@1|root,2Z9B4@2|Bacteria,1TS7Y@1239|Firmicutes,249S0@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01528	657322.FPR_08680	8.21e-216	596.0	COG0583@1|root,COG0583@2|Bacteria,1V09D@1239|Firmicutes,24H18@186801|Clostridia,3WJMG@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFPJHIIC_01530	657322.FPR_16180	1.42e-51	170.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,3WGIU@541000|Ruminococcaceae	186801|Clostridia	EM	Belongs to the DapA family	nanA	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
NFPJHIIC_01531	657322.FPR_16190	5.76e-107	308.0	COG2731@1|root,COG2731@2|Bacteria,1VCI9@1239|Firmicutes,24QNC@186801|Clostridia,3WM8D@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
NFPJHIIC_01532	657322.FPR_16200	1.5e-162	455.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3WJ12@541000|Ruminococcaceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
NFPJHIIC_01533	657322.FPR_05560	0.0	872.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NFPJHIIC_01534	657322.FPR_05550	2.73e-96	290.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,3WH2H@541000|Ruminococcaceae	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
NFPJHIIC_01535	657322.FPR_29750	1.33e-253	697.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24AZ4@186801|Clostridia,3WNAA@541000|Ruminococcaceae	186801|Clostridia	H	aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NFPJHIIC_01536	657322.FPR_25720	1.28e-190	532.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,3WMZU@541000|Ruminococcaceae	186801|Clostridia	H	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
NFPJHIIC_01537	657322.FPR_25710	3.88e-212	587.0	COG0524@1|root,COG0524@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,3WMTE@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	-	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
NFPJHIIC_01538	657322.FPR_26010	5.33e-109	343.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
NFPJHIIC_01540	397290.C810_02908	3.76e-294	815.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,27JZY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1
NFPJHIIC_01541	657322.FPR_28270	4.12e-80	253.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
NFPJHIIC_01542	657322.FPR_12620	1.12e-59	189.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3WHG1@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
NFPJHIIC_01543	657322.FPR_12610	1.09e-252	692.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3WHV3@541000|Ruminococcaceae	186801|Clostridia	E	aspartate-ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
NFPJHIIC_01544	748224.HMPREF9436_00550	4.51e-67	209.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,3WK0Y@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
NFPJHIIC_01545	657322.FPR_12420	3.71e-74	221.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3WK9V@541000|Ruminococcaceae	186801|Clostridia	P	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NFPJHIIC_01546	657322.FPR_12410	6.81e-111	317.0	28YYK@1|root,2ZKRH@2|Bacteria,1W3K6@1239|Firmicutes,255EI@186801|Clostridia,3WR29@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFPJHIIC_01547	657322.FPR_03600	4.11e-105	304.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,3WIWV@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
## 1376 queries scanned
## Total time (seconds): 207.0696897506714
## Rate: 6.65 q/s