LOCUS       c00046_gnlPro..         9553 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFPJHIIC_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:55:17
            Original ID  :: gnl|Prokka|NFPJHIIC_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9553
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9553
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:5597]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..5597
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..9553
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9553
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(2..451)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 120.6;
                     E-value: 2.3e-37)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_1"
                     /sec_met_domain="ETF (E-value: 3.7e-38, bitscore: 120.6,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADFNEYKGVWVFCEQRQGALMSTDFELVSEARKLADELGCEVTG
                     LLLGDNVEGIAKELGGYGADKVLVCDSPLLKDYTTDAYAKVVCDMVNEYKPEVLLIGAT
                     NIGRDLGPRCAARLHTGLTADATHLDIDTAKYIDFLKESSTIDLSK"
     CDS             complement(473..1267)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 156.6;
                     E-value: 2e-48)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="ETF (E-value: 3.3e-49, bitscore: 156.6,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVCVKQVPDTSGKVSVKPDGTLDRASMATITNPDDLNALEAA
                     LKLKDATGCEVVVVTMGPPPAEGMLRELLARGADKAVLVSGREFGGSDTFATSQILAAA
                     VNKIGVGPEDVVFCGRQAIDGDTAQVGPQIAEKLHLPQVTYVADIQKDGNTLTVKRMLE
                     DGYMMVKVQTPCLLTCIKELNQPRYMSVNGIFTCYDKPMEVFDYNALKDDPLIEVDTIG
                     LKGSPTNVFKSFTPPQKGAGTMLKGDDTAAQLAGILAKKHLI"
     CDS             complement(1285..2454)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3e-50, bitscore:
                     159.8, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.7e-30, bitscore:
                     93.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-40, bitscore:
                     128.4, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLSKQQQMVQKMYREFAENEVKPLAKKVDAEEYFPKETVEKM
                     GKLGMMGIYFPTEVGGAGGDVLSYVMAVEELSKVCGTTGVIVSAHTSLCAAPIYENGTP
                     EQKAKYLPKLCSGEWLGAFGLTEPGAGTDAQGQQTIAKEDGDYWVLNGSKIFITNAGFA
                     DVFIVIAVTDNVLDKRGRPTKLCSAFIVERTDPGFSVGKAEDKMGIRGSSTCELIFEDC
                     RIPKDRMLGVRGKGFQLAMATLDGGRIGIASQALGIAEGALEETIAYVKERKQFGRAIA
                     AFQNTQFELAEMKARVEAAKYLVYAAALKKQQAMDGAKVRYSVEAAQAKLIAARTASDV
                     TRRCLQLFGGYGYTRDYPIERMMRDAKITEIYEGTSEVQMMVISGALLK"
     CDS             complement(2559..3431)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_4"
                     /sec_met_domain="HCDH (E-value: 7.6e-35, bitscore: 109.0,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 2.1e-61, bitscore: 196.4,
                     seeds: 60, tool: rule-based-clusters)"
                     /sec_met_domain="F420_oxidored (E-value: 5e-08, bitscore:
                     23.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGVIGAGTMGQGIAKAFAQVEGNTVALCDIKQEWAENGLAKIK
                     KGYEKLVAKGKMTQEKADAIVAAITPGLKEDLCADCDLVVEAAFEDMKVKQTTFGELDK
                     ICKPECVFASNTSSLSITEIGKGLSRPLIGMHFFNPADRMKLIEVIAGCNTPAETVEKI
                     KEISVAIGKSPVQVNEAAGFVVNRILIPMINEAAFIKMEGVSDIAGIDTAMKLGANHPM
                     GPLELGDFIGLDICLAIMDVLYNETGDSKYRACPLIRKMVRGGNLGCKTGKGFYVYNAD
                     RTKTPVDQL"
     CDS             complement(3471..4256)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_5"
                     /sec_met_domain="EC1_2-faecali (E-value: 1.8e-93, bitscore:
                     301.8, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFVKTEVQGAVEIITIDRPKALNALNPEVLADLKAAFEAVDQET
                     VRCIVLTGEGDKSFVAGADIGSMSTMTKAEGEAFGKLGNDVFLMIEHFPIPVIAAVNGF
                     ALGGGNELAMSCDFRICSDNAVFGQPEVGLGITPGFGGTQRLARLVGMGMAKQLVYSAL
                     NIKADEAYRIGLVNAVYPQAELMENVLKLAGKIAKNAPIAVRNCKKAMNDGISLPIEKA
                     VEVEEKLFGDCFETHDQQEGMACFLSREKPKPKAVFTNN"
     CDS             complement(4380..5597)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="Thiolase_N (E-value: 3.2e-94, bitscore:
                     304.4, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 4.6e-49, bitscore:
                     154.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIVIASACRTAIGKFGGTLANVPAVELGSIVIKEALNRANVKP
                     EQVDHVYMGCVIQAGLGQNVARQAALKAGLPIETPAVTVNVVCGSGLNCVNMAAQMIEA
                     GDADIVVAGGMENMDMAPFALQKARYGYRMGAPMGKSEIVDTMVNDALWDACGFNKHMG
                     MTAENVCTNETYQKKYGYSPITREMLDEFSYNSQLKADKAIKDGAFKDEIVPVVIKGKK
                     GDTVFDTDEGPRLTPVEKLATLKPAFTKDGIVTAGNSSAINDGAAALVVMSEEKAKELG
                     VKPLATWVAGALAGVEPEVMGLGPIAATKKVMAKTGMTVADMDLVEANEAFAAQSIAVG
                     EALGFDKDKLNVNGGAIALGHPVGASGARILVTLLYAMKHRGAHKGLATLCIGGGMGCA
                     TIVEMD"
     CDS             complement(5639..6178)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_7"
                     /sec_met_domain="CTP_transf_like (E-value: 3.2e-26,
                     bitscore: 81.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATAVYPGSFDPVTKGHLDIIKRAAKINDHLIVAVLINSAKHPLF
                     TVEERVAMLQECCKNIPNVTVESFDGLTVEFAKKRHASVMVRGLRAVTDFENEIQLAQT
                     NHALMPGIETMFLATSIKWSYLSSTIVKEAAYYGSDISKFVTPNVEKAVSEKYAQLRER
                     EKSDTAKMPQGVLING"
     CDS             6681..8027
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hyd_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AcetylCoA_hydro"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 7.9e-62,
                     bitscore: 197.2, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 4.2e-29,
                     bitscore: 91.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKELYAQKLMTAAQAAALVKSGDWVDYGWAVNTPVAVDAELAK
                     RLPELEGVNFRGGILMWVPEIFQIDDPAAHMTWNSWHMGGIERKAIAQGFSFYSPIRYS
                     ELPRYYRESNDPVDVAVFQVTPMDEHGYFNFGPSASHLGAVCEKAKKIIVEVNTNMPRC
                     LGGMENCVHVSQVSGIVEGANPPIGQMAAAGAATEVDLKVANLIVPQIPNGACLQLGIG
                     GMPNAIGGLIAQSDLKDLGVHTEMYVDAFVDIAKAGKINGSRKQLDKGRQVYAFGAGTQ
                     KMYDYLNDNPECMSAPVDYTNDIRSISALDNFISINNAVDIDLFGQVNAESAGVKHISG
                     AGGQLDFVLGAYLSKGGKSFICLSSTFFNKKTGQLESRIRPTLENGSIVTDTRANVHYL
                     CTEYGCVNLKGLTSWEKAEALISVAHPDFREELIREAEKLHIWRRSNKI"
     CDS             8079..9338
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MDKKPHIKPYLYGMLAGFGAIALSIIFFFLIYRFDGFGSAISTLT
                     GILMPFIYGAVIAYLLKPVCNSIENFLRRFIPEKMNGLINALSVALTILFGLLLVYALV
                     MMIVPQLITSVTTLYYTAQANITKFMNWANHLEFIEKNEQITELLNSAYAALNTNLDTW
                     NTWLKNTLLPSMQNILSGAAIGVLNVVTVAKNLIIGIIVAVYMLASRKRFVQQGKLVLH
                     SIVRPRWAQLVTEEVKYADKMFGGFINGKIMDSAIIGVLCYIGCLIFKFPSALLVSVII
                     GVTNVIPFFGPFIGAIPATLLILIQSPIKALWFVLFVLVLQQLDGNIIGPKILGNTTGL
                     SSFWVLFAILLFGGLWGFVGMIVGVPLFAVIYDVIKKLVIHGLQRHQELTLLNSYHDQF
                     GDPADDAAAQPAASQPAENQ"
     CDS             9434..9553
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MNIGFWLCGVLVIPFVIIGVLFAIFKEKAAKFVSGFNSLP"
ORIGIN
        1 gcttggacag gtcgatggtg gagctctcct tcaggaagtc gatgtacttt gcagtatcga
       61 tatccagatg ggtagcgtcg gcggtcaggc cggtgtgcag acgggctgcg cagcgggggc
      121 cgaggtcacg gccaatgttg gtagcgccga tcagcagcac ctcaggcttg tactcgttga
      181 ccatatcgca cacgacctta gcgtatgcat cggtggtgta atccttcagc agggggctgt
      241 cgcagaccag aaccttgtcg gcaccgtagc cgcccagttc cttggcaatg ccctcaacgt
      301 tgtcacccag cagcaggccg gtgacctcgc agcccagctc gtcggccagc ttacgggcct
      361 cgctaaccag ctcgaagtca gtggacatca gtgcgccctg gcgctgctcg caaaagaccc
      421 atacgccctt gtattcgtta aaatcagcca ttgtaatcct atgctccttt catcagatca
      481 ggtgcttctt ggccaggata ccagccagct gtgcggcagt atcgtcgccc ttcagcatgg
      541 tgcctgcgcc cttctgcgga ggagtgaagg acttaaagac gttcgtcgga gaacccttca
      601 gaccgatggt atcgacctcg atcagcggat cgtccttcag tgcgttgtaa tcgaacactt
      661 ccatgggctt gtcgtagcag gtgaagatgc cattgacgct catgtaacgg ggctggttca
      721 gctccttgat gcaggtcagc aggcagggag tctgcacctt gaccatcatg tagccgtcct
      781 ccagcatacg cttcacggtc agggtgttgc catccttctg gatgtcagcc acataggtga
      841 cctgcggcag atgcagcttt tcagcgatct gggggccgac ctgtgcggta tcgccatcga
      901 ttgcctgacg gccgcagaac acaacgtcct cggggccaac gccgatctta ttgacagcag
      961 cagccaggat ctggctggtt gcaaaggtat cggaaccgcc gaactcacgg ccggagacca
     1021 gaacagcctt atcagcgccg cgggccagca gctcacgcag catgccctct gccggcgggg
     1081 gacccatggt gacaacaacg acctcgcagc cggtggcgtc cttcagtttc agggcggcct
     1141 ccagagcgtt caggtcatcg gggttggtga tggttgccat ggatgcacga tccagagtgc
     1201 catcgggctt gacggacacc ttgccggagg tatcaggaac ctgctttaca caaacaattg
     1261 ctttcattgt aactcttgcc tcccttactt cagcagcgcg ccggaaatga ccatcatctg
     1321 cacttcgctg gtgccctcgt agatctcggt gatcttggca tcacgcatca tgcgctcgat
     1381 ggggtagtca cgggtgtagc cgtaaccacc gaacagctgc aggcaacggc gggtcacatc
     1441 gcttgcggtg cgggccgcga tcagcttagc ctgtgcagcc tcgacgctgt aacgaacctt
     1501 tgcgccatcc atagcctgct gcttcttcag agcggcagca taaaccagat acttagcagc
     1561 ctcaacacga gccttcatct cagccagctc gaactgggtg ttctggaaag cggcgatggc
     1621 acgaccgaac tgcttgcgct ccttgacgta agcaatggtc tcctccagag cgccctcggc
     1681 aatgcccaga gcctgagaag cgattccgat acggccaccg tccagcgtag ccatagccag
     1741 ctggaagccc ttgccgcgca cgcccagcat acgatccttc gggatgcggc aatcctcaaa
     1801 gatcagctca caggtagaag aaccgcggat acccatcttg tcctctgcct taccaacaga
     1861 gaagcccggg tcggtgcgct ccacgatgaa ggcggagcag agcttggtgg gacggccgcg
     1921 cttatccagc acgttatcgg taacggcgat gacgatgaac acatcagcaa agccggcgtt
     1981 ggtgatgaag atcttggagc cgttcagcac ccagtaatcg ccatcttcct tggcaatggt
     2041 ctgctgaccc tgtgcatcgg taccagcgcc cggctcggtc aggccgaaag cgcccagcca
     2101 ctcgccgctg cacagcttcg gcaggtactt agccttctgc tcgggggtgc cgttctcgta
     2161 aatgggagca gcgcacaggc tggtgtgagc agagacgatg acaccggtgg tgccgcagac
     2221 cttgctcagc tcctccacgg ccatgacgta ggacagcaca tcgccgcctg caccgccgac
     2281 ctcagtcggg aaatagatgc ccatcatgcc cagcttgccc atcttttcga cggtctcctt
     2341 ggggaagtat tcctctgcgt caaccttctt tgccagaggc ttgacttcgt tctcagcaaa
     2401 ctcgcggtac attttctgca ccatctgctg ctgcttggac agagtaaaat ccatcgctat
     2461 atcctcctaa cgggtctttt tcatttaccg gaattgcccg gtgcaaacaa attcctcccg
     2521 gccgcttttc cacggtcggg agaaacgttt atcagaattt acagctggtc aacaggggtc
     2581 ttggtgcggt ctgcgttgta aacgtagaag cccttaccgg tcttgcagcc cagattgccg
     2641 ccgcgcacca tcttgcggat cagcgggcag gcacggtact tgctgtcgcc ggtctcgttg
     2701 tacagcacgt ccataatggc caggcagata tccagaccga tgaagtcgcc cagctccagg
     2761 ggacccatgg ggtggttagc gcccagcttc atagcggtgt cgatgccagc gatatcggaa
     2821 acgccctcca tcttgatgaa ggcagcctcg ttgatcatgg ggatcaggat gcggttgacc
     2881 acaaagccgg cagcctcgtt gacctgaacg gggctcttgc cgatggcaac ggagatctcc
     2941 ttgatcttct caacggtctc agcgggagtg ttgcagcctg cgatgacctc gatcagcttc
     3001 atgcggtctg cggggttgaa gaagtgcata ccgatcaggg gacgagacag acccttgccg
     3061 atctcggtaa tggacagaga agaagtgttg gaagcgaaga cgcactcggg cttgcagatc
     3121 ttatccagct cgccgaaggt ggtctgcttg accttcatat cctcgaaagc agcctcaacg
     3181 accagatcgc agtctgcgca cagatcttcc ttcaggcccg gggtgatggc ggcaacgatt
     3241 gcgtcggcct tctcctgagt catctttccc ttagcgacca gcttctcgta gcccttcttg
     3301 atctttgcca gaccattctc ggcccactcc tgcttgatgt cgcacagagc aacagtgttg
     3361 ccctcaacct gtgcaaatgc ctttgcgatg ccctgaccca tagtgccagc gccgataaca
     3421 ccgatcttca taggaaatct ctcctttaat atcaaaaatt atgtaatgga ttagttgttg
     3481 gtgaacactg ccttgggctt cggtttctca cgggacagga agcaggccat gccctcctgc
     3541 tggtcgtggg tctcgaagca atcgccgaac agcttctcct cgacctcaac agccttctcg
     3601 atgggcaggc tgatgccgtc gttcattgcc ttcttgcagt tgcgcacagc aatgggagcg
     3661 ttctttgcga tcttgccggc cagcttcagg acattctcca tcagctcagc ctgcggatac
     3721 acggcgttga ccagaccgat gcggtaagcc tcgtcagcct tgatgttcag agcagagtag
     3781 accagctgct ttgccatgcc catgccaacc agacgagcca gacgctgggt gccgccgaag
     3841 cccggggtga tgcccagacc gacttccggc tgaccgaaca cagcgttgtc agagcagatg
     3901 cggaaatcgc agctcatagc cagctcgttg ccgccgccca gtgcaaagcc gttgacggct
     3961 gcgatgacgg ggatggggaa atgctcgatc atcaggaaca catcattgcc cagcttgccg
     4021 aaggcctcgc cttctgcctt agtcatggtg ctcatagaac cgatatcagc accagcaacg
     4081 aagctcttgt cgccttcgcc ggtcagaacg atgcagcgga cagtctcctg atcgactgcc
     4141 tcaaaagcag ccttcaggtc agccagaacc tcggggttca gggcgttcag tgccttggga
     4201 cggtcgatgg taatgatctc aacagcgccc tgcacctcgg tttttacaaa tgccattgtg
     4261 aaaacctcca tttcatacag ttcagttttt tcaaaacagc ccccggaacg cgggagagct
     4321 ctccggttcc ctccggcgct ccgggtctgt ggttcagtca ggattcagag aaagagtgct
     4381 tagtccatct caacgatggt agcgcagccc atgccgccgc cgatgcacag ggtagccaga
     4441 cccttgtgag caccacggtg cttcatagcg tacagcaggg tgaccagaat acgagcgccg
     4501 gaagcgccga ccgggtgacc cagagcgatt gcgccgccgt tgacgttcag cttgtcctta
     4561 tcaaagccca gagcctcgcc gacagcgatg gactgtgctg cgaatgcctc gttggcctcg
     4621 accagatcca tatcagcaac ggtcatgccg gtcttggcca tgaccttctt ggtagcagcg
     4681 atggggccca gacccatgac ctcgggctca acgcctgcca gagcaccggc gacccaggtt
     4741 gccagaggct tcacgcccag ctccttagcc ttctcctcgc tcatgacgac cagagcagca
     4801 gcgccgtcgt tgatggcgga agagttgccg gcggtcacga tgccgtcctt ggtgaaagcg
     4861 ggcttcaggg tagccagctt ctcgaccggg gtcagacggg ggccttcatc ggtatcgaac
     4921 acggtgtcgc ccttcttgcc cttgatgaca acaggaacga tctcgtcctt gaaggcgccg
     4981 tccttgatgg ccttgtcagc cttcagctgg ctgttgtatg agaactcgtc cagcatctca
     5041 cgggtgatgg ggctgtagcc gtacttcttc tgataggtct cgttggtgca gacgttctca
     5101 gcggtcatgc ccatgtgctt gttgaagccg caggcatccc acagtgcatc gttgaccatg
     5161 gtatccacga tctcgctctt gcccatggga gcgcccatgc ggtagccata gcgagccttc
     5221 tgcagtgcga agggagccat gtccatgttc tccatgccgc ctgcaacaac gatatcagca
     5281 tcgcctgcct cgatcatctg agcagccatg ttcacgcagt tcagaccaga gccgcagacc
     5341 acgttgacgg tgacggcggg ggtctcgatg ggcagaccag ccttcagggc agcctgacga
     5401 gcgacgttct ggcccagacc agcctgaatg acgcagccca tgtaaacatg atcgacctgc
     5461 tcgggcttga cgtttgcacg gttcagagct tccttgataa cgatggagcc cagctcaaca
     5521 gcgggaacgt tggccagagt gccaccgaac ttgccgatag cggtgcggca tgcagatgcg
     5581 ataacgatct ttttcatgtg aatagcctcc tgaattgtgt atgtgtgtta cttatcggtt
     5641 acccatttat caaaacgccc tgcggcattt ttgcggtatc agatttttcc ctctcccgga
     5701 gctgtgcgta tttttcgctg acggcttttt ccacattggg tgtgacgaac ttgctgatgt
     5761 cactgccgta gtacgccgct tcctttacga tggtggagga aagataactc catttgatgc
     5821 tggtggcaag gaacatggtc tcgatgccgg gcatcagtgc gtggttggtc tgcgcaagct
     5881 ggatctcgtt ttcaaagtcc gttactgccc gcagcccgcg caccattacg gatgcgtgac
     5941 gcttttttgc gaactccacg gtcaggccgt cgaaactttc cacggtcacg ttggggatgt
     6001 tcttgcagca ttcctgtagc atagccaccc gctcttccac tgtgaacagc ggatgcttgg
     6061 cgctgttgat cagcaccgcc acaatgaggt ggtcgttgat ctttgctgcg cgtttgatga
     6121 tatcaaggtg tcccttggtg accggatcga acgacccggg ataaactgct gttgccatcg
     6181 gtcagtgtcc tccttgtgcg ctgtaattac taagcgcgat gtggttctgc catgatagca
     6241 ctttccagcc ttgggtgcaa cctgaaactg ctgcggtgcg ttttatcgtt aaattttaaa
     6301 cgaatcatcc cgcactgctc cgcagttgct tcccacgcta ttagtaaagc acatcgtcaa
     6361 aattttatca agtctttttc tcaacttttt tgttttttgc gtaccaaaca atccccacac
     6421 aaagctaaga aaactgttca ttctgctata ctggctgttt tttagccaaa actattgatt
     6481 ctacactttg ttaatgttat aactaagttg agctgttctg cgcagagcgg agcacacact
     6541 gctgccttgt ttataaggtt accatacaga tgtggcaaaa cggtgtgcat tccgcaaaac
     6601 aggcgtaaaa cggctgcata atttgtccgc acagaattgt ttacaattct tttatgtatt
     6661 ttaagagagg atggtttata atggattgca aggaactgta cgcacagaag cttatgactg
     6721 ctgcgcaggc tgccgctctg gtcaaaagcg gcgactgggt ggattacggc tgggctgtga
     6781 acacccctgt ggccgtggac gccgagctgg caaaacgcct gccggagttg gaaggagtca
     6841 acttccgggg cggcatcctg atgtgggtgc cggagatctt ccagatcgac gaccccgctg
     6901 cccacatgac ctggaacagc tggcacatgg gcggcattga gcgcaaggcc attgcgcagg
     6961 gcttctcctt ctactccccc atccgctact ctgagctgcc ccgctactac cgcgagagca
     7021 atgaccccgt ggatgtggca gtatttcagg tgacccccat ggacgagcat ggctacttca
     7081 acttcggtcc cagcgcttcg catctgggtg ctgtgtgcga aaaggccaag aagatcatcg
     7141 tggaggtcaa caccaatatg ccgcgctgcc ttggcggcat ggagaactgc gtacacgttt
     7201 ctcaggtaag cggcatcgtg gagggcgcaa atccccccat cggccagatg gcagctgccg
     7261 gtgccgctac cgaggtggac ctgaaggtag ccaacctcat cgtgccgcag atccccaacg
     7321 gtgcctgcct gcagctgggc atcggcggta tgcccaatgc catcggcggg ctgattgcac
     7381 agagtgatct gaaggatctg ggcgtgcaca ccgaaatgta tgtggatgcc tttgtggata
     7441 ttgccaaggc cggcaagatc aacggcagcc gcaagcagct ggacaagggc cgtcaggtct
     7501 acgcctttgg tgccggcacc cagaagatgt acgattacct gaacgataac ccggagtgta
     7561 tgtctgcccc ggtggactac actaacgaca tccgcagcat ttccgcactg gacaacttta
     7621 tttccatcaa caatgccgtg gatatcgacc tgtttggtca ggtgaatgcc gaaagcgccg
     7681 gtgtgaagca catttccggc gcaggcggtc agctggactt cgtgctgggc gcataccttt
     7741 ccaagggcgg caagagcttt atctgcctgt cctccacctt ctttaataaa aagaccggcc
     7801 agctggaaag ccgtatccgt cccacgctgg agaatggcag catcgttacc gacacccgtg
     7861 ccaatgtgca ctatctgtgc accgagtatg gctgtgtgaa cctgaagggc ttgacctctt
     7921 gggaaaaggc cgaggctctg atcagcgtgg cacacccgga cttccgcgag gagctgatcc
     7981 gcgaggctga aaagctgcac atctggcgca gaagcaacaa aatttaataa gcgctgtggg
     8041 tattcccgct gcccgcagca ggaatggagt ttgtcatgat ggacaaaaag ccgcacatca
     8101 aaccgtatct ctatgggatg ctcgcagggt ttggtgccat tgcactgagc atcatcttct
     8161 ttttccttat ttaccgcttt gacggctttg gctcggccat ctctaccctg accggcatcc
     8221 tgatgccctt tatctacggt gccgtcattg cctatctgct caagccggtg tgcaacagca
     8281 tcgaaaactt tctgcgccgg ttcatcccgg aaaagatgaa cggtctgatc aacgcgctgt
     8341 ccgtggcgct taccatcctg ttcgggcttt tgctggtgta tgcactggtc atgatgatcg
     8401 tgccgcagct cattaccagc gtgactaccc tgtactacac cgcgcaggcc aacattacaa
     8461 agttcatgaa ctgggcaaac catctggagt ttattgaaaa gaacgaacag atcacggagc
     8521 tgctcaattc ggcttacgct gccctgaata ccaatctgga cacatggaac acatggctca
     8581 agaacaccct gctgccctcc atgcagaaca ttctgagcgg cgcagccatt ggtgtgctga
     8641 acgtggtgac ggtggccaag aacctgatca tcggcatcat cgtggcggtg tatatgctgg
     8701 ccagccgcaa gcggttcgtg cagcagggca agttggtgct gcacagcatc gtccgccccc
     8761 gctgggcgca gctggtcact gaggaagtga agtacgcaga caaaatgttc ggcggtttca
     8821 tcaacggcaa gatcatggac tctgccatca tcggcgtgct gtgctatatc ggctgcctga
     8881 tcttcaagtt ccccagtgcg ctgctggtat cggtgatcat cggtgtgacc aacgtgatcc
     8941 ccttcttcgg cccctttatc ggtgccattc ccgccacgct gctcatcctc atccagagcc
     9001 ccatcaaggc gctgtggttc gtgctgttcg tgctggtttt gcagcagctg gacggcaaca
     9061 tcatcggacc caagattctg ggcaacacca ccggcctttc cagcttctgg gtactgttcg
     9121 ccatcctgct gtttggcggc ctgtggggtt ttgtgggcat gatcgtgggt gtgccgctgt
     9181 tcgccgttat ctacgacgtc atcaaaaagc tggtcattca cggcttgcag cgccatcagg
     9241 agctgaccct gctgaacagc tatcacgacc agttcggcga ccccgcagac gatgcagccg
     9301 cacagcccgc tgcatcgcaa cctgctgaga accagtaaac cttccctgcc ccgcatcaga
     9361 gctcttccga tgcggggtat tttttaatca tattacaaat tataaatcgg aatttgtgaa
     9421 ggaggaacat actatgaata tagggttttg gctatgtgga gttttggtta ttccatttgt
     9481 gattatagga gtgttatttg caatatttaa agaaaaagcg gctaaatttg tttcgggatt
     9541 taattcatta ccg
//
