LOCUS       c00152_gnlPro..         4005 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFPJHIIC_152.
ACCESSION   c00152_gnlPro..
VERSION     c00152_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:55:17
            Original ID  :: gnl|Prokka|NFPJHIIC_152
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4005
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4005
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4003]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4003
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4005
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4005
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..685)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg152_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1.8e-83, bitscore:
                     268.9, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGTYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLA"
     CDS             complement(852..1871)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg152_2"
                     /sec_met_domain="IlvN (E-value: 2.4e-75, bitscore: 239.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4e-66, bitscore: 209.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHENFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVCELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             complement(1970..2533)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg152_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.1e-29, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKSLERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHMQKPPQEVRSVQLPPPGARRA"
     CDS             complement(2549..4003)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg152_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.2e-52, bitscore:
                     163.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLATSGPGATNLVTGIATAYMDSVPMVAFTGNVPTSSIGKDGFQE
                     AYIEGITVPITKHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPKDVTAAVCEFTP
                     KQPEPIRTVTTYNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLRDLLHKAEIPAT
                     YTLMAAGVVPYGDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDRVALNPKTFAKN
                     ATIIQIDIDASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPEWMKMIQSWQAQDYH
                     PVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSRGFITSGGLGTM
                     GFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIITVIFNNSVLGMV
                     RQWQTNFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFADAMQQKGPTWI
                     ECIIDKDEKVLPMIPGGGDINDIIME"
ORIGIN
        1 ttgccagctg caggcgcttg gagtacacag ccgggatggt gccgttgccg ggcagggcaa
       61 tgccgatggc ctcgcacagg cagttcatgc tgttggcggt gtacataccg gagcagctgc
      121 cgcagctggg gcagcagttg caggtgcagt cttccagctg ctcgtcggtg atcataccgg
      181 ccttataggc acccacggcc tcgaacatct tggaaaggct cacttcctcg ccgccgtaag
      241 taccggccag catggggccg ccggagcaga ccacagcggg cacatccatg cgcaccgctg
      301 ccatcaccat gccgggcacg atcttatcgc agttgggcac cagcacaagg ccgtccagct
      361 ggtgtgccat cagcatggtc tccacactgt cgcagatcag ctcgcgggag gccagagagt
      421 acttcatgcc cacatgaccc atggcaatgc cgtcgcatac accgatggcg gggatcagga
      481 tgggcgtacc gccggccatc tgcacaccgg ccttgacggc ctcggcgatc ttatccagat
      541 tcatgtgtcc gggcacgatc tcgctgtaag cgctcaccac gccgatgagg gggcgttcca
      601 gctcctccgg ggtgtagccc agcgcataaa acaggctgcg gttgggcgcg cgctccgagc
      661 ccttggtcac gttgtcactt ctcattgcaa atcctctttt ctgataaagc cctctccgtc
      721 acggctgcgc cgtgccacct ctcccgaggg ggagaggttt tcgcggagga gctataaggt
      781 tcccttttca acaaaaactc cccctttcgg gggagctggc cgccgaaagg cggcctgaga
      841 gggttttcct cttacttctt cagccagctc atcatgctgc gcagctcagc acccaccttc
      901 tcgatgggca gctcggcctc catacggcgc ttggcaagga agtgcacctt gcggccgccc
      961 ttggggctca tctcggtcag gaactcggaa gcaaaggtgc cgtcctggat ctcggtcaga
     1021 accttcttca tctccttgcg ggtctcctcg gtgatcaggc gcttgccggt gcggtaatcg
     1081 ccgtactcag cggtgttgga gatggagtag cgcatcttgg agaagccgcc ctcgttgatc
     1141 aggtcaacga tcagcttcat ctcgtggcag gtctcaaagt atgccatctc gggctcgtag
     1201 ccagcctcca ccagcgtatc gaagcctgcg tggatcagct cgcagacacc gccgcacaga
     1261 actgcctgct cgccgaacag gtcggtctcg gtctcctcct tgaaggtggt ctgcaggatg
     1321 cctgcacggc ctgcgccgat gccggaagcg tatgccagag cgatatcctt ggccttgccg
     1381 gtgtagtcct gctccacgca gatcagagag gggcagccct caccctcggt gtacaggcgg
     1441 cggacgatgt ggccggggcc cttgggagcg atcatgatga cgtccacgtt cttgggagcg
     1501 gtgatggtct tgaagtggat gttgaagccg tgtgcaaagg ccagtgcctt gccctcggtc
     1561 atgtagggag caacctgcgt gttgtagata tcggcgcaca gctcgtcggg caccagcatc
     1621 atgacaacat caccggcctt ggcagcctct tccacttcca tcaccttgaa gttttcgtgg
     1681 gtggcagcga actcagaagc ctttgcccag tgggcagagc ccttgcgcag gccgaccaca
     1741 acgttgacgc cgctctcggc cagattctca gagtgtgcat gaccctggct gccgaagccg
     1801 atgacagcga cggtcttgcc gtccagcacg ccgaggttgc agtcggaatc gtagtatttc
     1861 ttgatagcca taatcgttag tctcctttta cattaactgg ttggtttatc ttccggtctt
     1921 gtatgctctg ttctatcttt cgctcaccct gagcggaaaa gcaaagtaat tatgcccgtc
     1981 ttgcgcccgg cgggggcagc tggacggagc gcacctcctg cggcggcttc tgcatatgct
     2041 ggtgcatccc gccgcgctcc agtgcggtaa cgccggtgcg gcactgctca aggatgttgt
     2101 agccctcgaa cattttcaaa aatgcgtcca gcttgtccgg ccggccgatg agttcaaaca
     2161 ccatgctgtc cggggaaaga tcaatgatct ttgccttgta aatgcaggcg atctcccgca
     2221 gctccgtgcg gttgtgcacg tccgattcca ccttgagcag cagcagctcc cgctccagcg
     2281 atttttcgct gtccagcacg aacacctgcc gggtgacttc cagccgctca gtctgcagca
     2341 ccagctgctg caaggccttt tcatcgctgg taatggtcac cgtgatgcgg ctgactgccg
     2401 ggtcgttggt ggcggacacc gtaaggctgt cgatattgaa gccgcggcgg cagaacaggc
     2461 tggacacccg ggccagaacg ccgctctggt tgtccaccag caggctgatg accctgcgct
     2521 gatcagattc catgatgctg tgtcctcctt attccatgat gatgtcgttg atatcgccgc
     2581 cgccggggat catgggcagc accttttcgt ccttgtcaat gatgcactcg atccaagtgg
     2641 ggcctttctg ctgcatggca tccgcaaacg cttcctgaaa ctccggcaga ttggtgcagc
     2701 ggtagccctt caggccaaag ccgtctgcca gcttgacaaa atcggtcttg cggtgggggt
     2761 cggtctggct gtaacgcttg ccgtaaaagt tggtctgcca ctggcgcacc atgcccagca
     2821 ccgagttgtt gaagatgacc gtgatgatgg gcagctcgta gctgacggcg gtgcaggctt
     2881 cgttcaggtt catgtggaag gaggcgtcgc cggtaaacat caccacacgc tgctggcgtc
     2941 ccagtgccat ctgggcacca atggcagcgc cgtagccaaa gcccatggtg ccaaggccgc
     3001 cgctggtgat aaagccgcgg ctcttggtgt ggcgcaggta ctgcgccgcc cacatctggt
     3061 gctggcccac atcggtaaca tacacggcgt cggggccgca ctggttgcac acctcgccga
     3121 tgacctgatg gggcatcagc cgggtggggt cggacacggg gtggtaatcc tgtgcctgcc
     3181 agctctggat catcttcatc cattccgggt gcttggcggg cttgatctgg ggcagcatgg
     3241 cgttcagcac ataggctgca tcgcccacga tggaaagatc cacgtccacg ttcttgccca
     3301 gctcgctggc gtcaatatcg atctggatga tggtggcgtt tttggcaaag gtcttggggt
     3361 tcagcgccac gcggtcggag aagcgggtgc ccaccgcgat gagcacatcg cactctgcca
     3421 ccgcccggtt ggaggtgtag cagccgtgca tacccagcat tcccagattc atcgggtcac
     3481 catagggcac aacgcctgcg gccatcaggg tgtaggtagc ggggatctcc gccttgtgca
     3541 gcagatcccg caacggctgg cagctggctg cgctgcgcac gccgccgcca aagtacacca
     3601 gcggacgctg tgcggcgttg atgaggtctg ccgcccagtg cacctgctcc tcattatagg
     3661 tagttacggt gcggatgggc tccggctgct tgggggtgaa ctcgcacact gctgcggtca
     3721 cgtccttggg gatatccacc agcaccgggc ccttgcggcc gctctgcgca atgcggaaag
     3781 ctgcccgcat ggtgtcagcc aagtcctcta cccggcgcac cgtgaagtta tgctttgtga
     3841 tgggcaccgt gatgccctcg atgtacgctt cctgaaagcc gtccttgccg atactgctgg
     3901 tgggcacgtt gccggtaaag gccaccatgg gcaccgagtc catataggcg gtggcaatgc
     3961 cggtgaccag attggtggca cccgggccgc tggtagccag cacca
//
