LOCUS       c00023_gnlPro..        15510 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHMINLCA_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:15:54
            Original ID  :: gnl|Prokka|FHMINLCA_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15510
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15510
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2460:5510]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2461..5510
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15510
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15510
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..95)
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MTHIQKTAPGPPTTMAVATPARFPVPTRLAS"
     CDS             complement(192..773)
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MPLSEASGTPPNRMMKAVQVQMTSVSVKTPRVWISPCFTGCETWA
                     VAATFGAEPIPASLLKSPRLMPCINAAPTAPPSVCSQPKASATISSSTSGSRPRLNSTT
                     PSASTMYPSAIIGTITPLTRAMRRMPPKMMSSVSAVSTTPTHTRSAPKAPSHAAQIVLL
                     CTELKANPKVTEISTANSTPIHLRPRPRSM"
     CDS             complement(1186..2340)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MKNRLPDLNVPARERIGWVDLLRVIACFLVVFSHSCDAFVAVFDS
                     DRATFLQGALAGSFVRACVPLFVMMSGVLLLPVRTGTGAFYRKRIGRVLLALVFWSLTL
                     PVLYYLYMRYVGTSSPSIDPALFTGEATLHKMWTFVFNFCYDTTPLWYLYMLIGLYLIM
                     PLISPWLERASRRELQSVLAIWGLTLLLPYVKMLAPALGYTGNYGNTGLYGVCDWNEFG
                     TFHYVSGFAGYLVLAFYLVKFPPAWNWRKTLGICIPTFLAGYLATGLGYVVMQKHFPGN
                     YAYLEIVWYFAGINVFMMTAPVFILVQKAAARPRAWLSRLAGATFGIYLCHFIFVQAGY
                     DLVQRIPGLPALARIALIACGAFAVSWAVVRLMQRWSVTRRLVE"
     CDS             complement(2461..3186)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 71.9;
                     E-value: 2.1e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.4e-27, bitscore:
                     87.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAGAG
                     TLTDPAEILRMAVDQKPFFGRRGGVTFSGGEPTFQAAELVPLVKSLKEAGIHVCIDSNG
                     GVWNPAVEELLGLVDLVLLDVKQADSERHRALTGRENAQTLRTAAWLEAHGKPFWLRYV
                     LVPGISDAEADIRALGERLGGYKSVERVELLPYHTLGVHKYEAMGLEYKLRDVRENTPE
                     QLDRAAALLREYFPTVVVN"
     CDS             complement(3282..5510)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_5"
                     /sec_met_domain="Gly_radical (E-value: 4.5e-46, bitscore:
                     146.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFIDGLWSKEINVTSFVQTNITPYLGDASFLAGPTERTKH
                     IWNLCLKALEEERQHNGVRALDNKTVSTVTSHKAGYIDRENELIVGLQTDELLKRAIKP
                     FGGINVVSRACKENGVEVDEKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGTDRLIEAKQEDLRNLTGPMTDARIRLREEVAEQIKALKDIR
                     TMGEYYGLDLSRPAHSAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GTIDESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTILWSPELPQGFKDFCAKVSADTSSIQYENDDLMREVRHS
                     DDYGIACCVSFQDIGRQIQFFGARTNLAKALLLAINEGRCENTGTLMVKGIPALSEGPL
                     RFEEVMRNYKMVLKEIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIALDSLSAIKYARVTPRRNAEGLTEAFDIEGEFPCYGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRLKGVAFAPGANPMHGRDKSGAIAS
                     LASVAKMRYRDSQDGISNTFSIVPKSLGPTAGERIENLVTMLDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFTKLSREHQLEVISRSFHERM"
     CDS             5740..6177
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MKRFWIALLGAGLFATAAFAGGDEVPVRMHELPDAAKTLVKKYFH
                     DIEVVSATMEKGVAPSYEVKLADGTEIDFDARGEWTDVERPGGVVPDGLIPQPILKFVA
                     ANYPGRHVRGVERDGRNHEVSLDNGLELKFNRRFRLVETDH"
     CDS             6355..6771
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MEELSLTTPALLFSAVSLILLAYTNRFLSYAQLVRTLKEQHLQHP
                     SKVTRAQIDNLRRRLHLTRTMQLLGVTSLFLCVVTMFLIYVGLMLLSAYVFGAALLLLV
                     GSLGVSIWEIQISVRALEIHLKDMENPLDKRDSE"
     CDS             complement(6881..7063)
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MPIRHRADNPPKPSFEKESFKKRRVTKMQRVRHFSETTDPYLCTV
                     KTGEPDSQVGFRLHK"
     CDS             complement(7063..9288)
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MSPLFTAIVVILALLAVMGIVVGVANDAVNFLNSALGSKVAPRRV
                     ILWVAAAGILVGTLTSSGMMEVARSGVFYPGQFSFQEIMMLFLGMMLGNVLLLDLYNTL
                     GLPTSTTVSMVFGLLGAAVAAALFRIAGDPGTSLQDLSQFINTGKAMVIIAAILLSVAL
                     AFVAGTLFMYISRLIFSFRYAAVFRRWGAVWCGISLAGILYFALFKGLKSSGLIPTSVS
                     AYVGDHVLVTLLAFWAAASLLLYIFQRMRLNIMRITILSGTFSLALAFAGNDLVNFIGV
                     PLAGYDAWRIAGEAGSETMMMGALEAPARANFLLLGVSGLIMVLTLFFSKKSQHVTETE
                     LSLASQHEGDERFGSTLISRSLVRATLVMNTMWTGLIPARVQKAIDRRFEPLPAEERSS
                     APYDMVRAVVNLTAASILIAIATSYKLPLSTTYVVFMVAMGSSLADRSWGRESAVYRIT
                     GVMAVISGWFITALGGFLIALAVTALLLWGGWIAVAALTALCAWLLVRSHLKTPGLKEE
                     AEKALLPLETAETPDEVLCACIGEVCTTMQEVTRIYNRTLVAVFKENRKVLKEMVRDSN
                     RLFEEARIRKYNVMPTLRRLQRCDIDTGHFYVQVTDYLSEVTKALIHITRPAFEHIDNN
                     HEGMSKEQIVDLMRVNDQVEAIFDKINDMLATKDFSDLDLVLEMRDKLFDTIVEAIKSQ
                     LRRINDVPSGSTRAGVLYLTILNETKTMMLQSRNLLKSQQYFLEAKK"
     CDS             complement(9622..11070)
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="MATALKHKLSYHRRLFLLLLVFSWTLVGCFILFQYGREKHFKAER
                     LDAQLQLFNLRMLDAVNAGAPPDAFIARSGAPCEGVRVTLIDPAGHVVFDNSLDTLPGA
                     NHLDRPEVAEALARGTGYTIRRHSESTDRNYFYSAMRGDRYIVRSAVPYSVPLGEILAT
                     DREFLWFMLGVTLLMSVAGYFATRRLGQNITRLNEFAERAERSERIDDLPAFPHDELGE
                     ISSHIIRLYARLQKTTADRDREHALALHEEQEKIRIKKQLTNNINHELKTPVAAIQGYL
                     ETLLANPSLDAQRRTDFLKKSAAQTERLRRLLADISTITRMDEASQLIQKERVVLNDLI
                     AEVTADMELKPADQRLRVNIDFPQQVEIVGSPSLLTSIFRNLADNAAAYSGGRDIFIRL
                     LSDTPEECTVSFADNGIGIGEEHLPHIFERFYRIDKGRSRKQGGTGLGLAIVKNAVAIH
                     GGTITARERERGGLEFVFTLKKHS"
     CDS             complement(11048..11728)
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MAKHKILVVDDEESLCEILQFNLEVEGYEADVAYSAEQALRMHPE
                     RYSLILLDVMMGEMSGFRMAQLLKADPETARVPVIFCTAKDSEDDTVAGLNIGADDYIT
                     KPFSVREVLARVRSVLRRTSAARAESESIRFEGLEIDLRRKVCTLDGKELQLTKKEFEI
                     LALLLSNRGVIFSREEILRRIWSDEVIVLDRTVDVNITRLRRKVGPYGEHIVTRLGYGY
                     GFEA"
     CDS             complement(11931..12995)
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MNDIQPITLPGIDPRRPLVIAGPCSAETEEQVLDTARSLAAEGIR
                     ICRAGLWKPRTKPGGFEGVGEAGIAWLQRVKRETGMYTSTEVATREHVATALKGGVDLL
                     WIGARTAANPFAMQEIADALRGTDVPVLVKNPVSPDLELWIGAIERIYNAGIRRIGAIH
                     RGFTSIDKSLYRNHPMWAIPIELHRRLPRLPIFCDPSHIGGKRELIAPLSQQAMDLGFD
                     GLIIEAHCSPDCAWSDKAQQVTPEALAYIIRNLVIRDESITTESLTELRSQIDKLDDQL
                     LELLSRRMRVSRDIGQYKKEHNMPVLQTQRYEELLARRAGQAGQMGMDREFMRTVLQAI
                     HEESIRQQMEVLGK"
     CDS             complement(13072..13917)
                     /locus_tag="ctg23_13"
                     /transl_table=11
                     /translation="MEQIAIQGIAGCYHETAARGYFADREIEVLPCLSFDELFARMAAD
                     PALLGIAAIENTIAGSLLPNHELLQQSRARIIGEQKLRISHVLAALPGQTPDDIAEVRS
                     HPIALMQCGDFLKTLPGMKIVERDDTAGSAREIAEGRLAGTAAICGADAARLYGLEILR
                     RGIETNKHNFTRFLLLADERRAAEFADPAHTDKASLLFTLPHTRGSLSKVLTVLSFYDI
                     NLTKIQSLPIIGREWEYRFYVDVTFDDPMRYRQAIDAARPLTSDFRILGEYAECPNPAI
                     "
     CDS             complement(14157..14906)
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MHIHVNTASEHLRDFAERLPELFDREGEVLHAGRNTIKAFEAEGE
                     RLVVKRFKRPNLLRAVIYTFFRRSKARRSYEHAVRLRALGVDSPEPVAWSEYRRRGLLC
                     DSYYVSRRSDYTPLSQTTARFPAAGTLPVLEAFARFTVQLHEKGIEHRDFNHGNILWDR
                     TPAGAYRFQLIDINRMHFDDRPLSSRACMINLRRLSCPAVAFLYILDRYAETRGWDVDD
                     TLLRGTFFRLAFGRRKQLRKRFRHRKG"
     CDS             complement(14971..15072)
                     /locus_tag="ctg23_15"
                     /transl_table=11
                     /translation="MPVRNRTRPSGKRSAFSARHPMKSAFLFRFRTT"
     CDS             complement(15109..15369)
                     /locus_tag="ctg23_16"
                     /transl_table=11
                     /translation="VLRAVAGDGRRGRGLRPETGHAQRFRLHKITYMRGTRPFQTACNP
                     HMWRYRASGPATTVRIEVADSFGRTSTKTMTRPKAFHIRMR"
ORIGIN
        1 tcgctggcca gccgcgtcgg cacggggaat ctcgcgggcg tcgccacggc catcgtcgtc
       61 gggggacccg gcgcggtctt ctggatgtgg gtcatcgccc ttgtgggcgt cgcgagcgct
      121 ttcgtcgagt cgaccctcgc gcagctttac aaacgccgcg gcagggactc tttcatcggc
      181 ggcccggcct actacatgga acgcggtctc gggcggaggt ggatgggcgt gctgttcgcc
      241 gtgctgatct ccgtgacctt cggattcgcc ttcaactcgg tgcagagcaa cacgatctgc
      301 gccgcgtggg agggagcttt cggcgccgat cgtgtgtggg tgggcgtcgt gctcacggcg
      361 ctgacgctgc tcatcatctt cggcggcata cggcgcattg cgcgtgtcag cggcgtgatc
      421 gtcccgatta tggcgctggg gtacatcgtg ctggcgctgg gcgtcgtgct gttcaacctc
      481 gggcggctgc ccgaagtgct ggaactgatc gttgccgacg ctttcggctg ggagcagacg
      541 ctgggaggcg cggtcggcgc ggcgttgatg cagggcatca agcggggact tttcagcaac
      601 gaggccggta tgggttcggc cccgaacgtc gccgccacgg cccacgtttc gcaccccgtg
      661 aagcagggac ttatccagac cctcggggtc ttcaccgata cgctcgtcat ctgcacctgc
      721 acggccttca tcatcctgtt cgggggcgtt cccgacgctt cgctcaacgg cattcagctg
      781 acgcaggcgg ctctggagag cgagatcggt cctgcgggcg gggtgttcgt cgccgtggcg
      841 atcttcctgt tcgccttttc gtcgatcatc ggcaattatt actacggcga agccaacatc
      901 cgcttcatca ctccgcggcc gtgggcgctg acgctctacc ggatgctggt cggcgcgatg
      961 gtgctcttcg gatccttggc gacgctcgat ctggcatgga gcctggccga tgtgacgatg
     1021 gcgctgatga cgctgtgcaa tctggcggcg atcgtgctgc tgggccgtca ggccttcctg
     1081 ctgctggccg actacacggc ccagaagcgg cagggcatca aaaatccggt cttcacgaaa
     1141 gaccggattc ccgaattgaa gacaaggccg agtgctggta gcgcattact ccaccagccg
     1201 gcgcgtcacg ctccaccgct gcatcagccg caccaccgcc cagctcacgg cgaaggctcc
     1261 gcaggcgatc agcgcgatgc gcgccagcgc gggaagtccc ggaatccgct gcacgaggtc
     1321 gtagccggcc tgaacgaaga tgaagtggca gagatagatg ccgaacgtcg cgcccgccag
     1381 ccgcgagagc catgcgcggg gccgtgcggc ggccttctgc acgaggatga agaccggggc
     1441 ggtcatcata aagacgttga tgccggcgaa ataccagacg atttcgaggt aggcgtagtt
     1501 gcccggaaaa tgtttctgca tcaccacgta acccagcccc gtggcgaggt atccggcgag
     1561 gaaggtcggg atgcagatgc ccaatgtctt gcgccagttc catgcgggcg ggaatttcac
     1621 gaggtagaag gccagtacga ggtaaccggc gaagcccgag acgtagtgga acgtgccgaa
     1681 ctcgttccag tcgcagacgc cgtaaagccc cgtgttgccg taattgcccg tgtagccgag
     1741 cgccggggcg agcatcttca cgtagggcag cagcagcgtc aggccccaga tcgcgaggac
     1801 gctctgcaac tcgcgccgcg aggcccgctc gagccacggg ctgatcagcg gcatgatcag
     1861 ataaagtcct atcagcatat agagatacca gagcggcgtg gtgtcgtagc agaagttgaa
     1921 gacgaaggtc cacatcttgt gcagcgtcgc ttcgccggtg aacagcgcgg ggtcgatcga
     1981 cggactggag gtcccgacgt agcgcatata caggtagtag agcacgggca gcgtcagcga
     2041 ccagaagacc agcgccagga ggacgcggcc gatccgcttg cggtagaaag cccccgttcc
     2101 ggtccgcacg ggcagcagca gcacgcccga catcatcacg aacagcggca cgcaggcccg
     2161 gacgaaactg cctgccaacg ctccttgcag gaaggtggcg cggtcgctgt cgaacacggc
     2221 gacgaaggcg tcgcagctgt gggagaagac caccagaaag caggcgatca cgcgcaggag
     2281 gtccacccag ccgatgcgtt cgcgggccgg gacgttcagg tcgggaagtc ggttcttcat
     2341 tgtcgcagaa atggatttcc ggcgaaggta cgaaaaaaat ccgggaccgc cgtgcgtttt
     2401 cgccgcggcg tcccggattt ttcgttgtcc gcactccctc cggcggacgt ccccttcggg
     2461 tcagttgacc accaccgtcg ggaagtattc gcgcagcagg gccgcggcgc ggtcgagctg
     2521 ttcgggggtg ttctcccgca cgtcgcggag tttgtactcc agccccatcg cctcgtactt
     2581 atgcactccg agggtgtggt aggggagcag ttcgacccgc tcgaccgact tgtagccgcc
     2641 gaggcgttcg cccagcgcac ggatgtcggc ttcggcgtcg ctgatgcccg gaaccagcac
     2701 gtagcgcagc cagaagggtt ttccgtgggc ttcgagccag gcggccgtgc ggagcgtctg
     2761 cgcgttttcg cgtccggtga gggcgcggtg gcgttcggaa tcggcctgct tcacgtccag
     2821 cagcaccagg tcgaccagcc ccagcagctc ttcgacggcc gggttccaca ccccgccgtt
     2881 cgagtcgatg cagacgtgga tgccggcctc cttcaacgac tttacgagcg gaacgagttc
     2941 cgcagcctgg aaggtgggtt ccccgcccga gaaggtcacg ccgccgcgcc gcccgaagaa
     3001 gggcttctgg tcgacggcca tgcgcaggat ctccgcaggg tcggtcaatg tgcccgctcc
     3061 ggcctcgatc gtgtcggggt tggcgcagta gagacagcgg aaattgcagc cttggaggaa
     3121 aacgacgagc cggagtcccg gcccgtcgaa tgttcccatg gattcgtaag aatgtacacg
     3181 aagcatgatt gttccttgtt tttgaataag ggggttcggg cgcaaaccgg gttccggtat
     3241 gcaaatcctg cgcccgcccc taaaagcggc ttttcaagcc gttacatcct ttcgtggaag
     3301 ctgcggctga tgacttcgag ctggtgttcg cggctcaact tggtgaagtt cacggcgtag
     3361 cccgagacgc ggatcgtcaa ctgcggatat ttctcggggt gctccatggc gtcttcgagc
     3421 atctcgcggt tcagtacgtt gacgttcagg tggtgtgcgc ccttggtgaa atagccgtcg
     3481 agcatcgtca cgaggttctc gatacgctct ccggccgtcg ggccgagcga tttgggcacg
     3541 atcgagaagg tgttcgaaat accgtcctgc gagtcgcggt aacgcatctt ggccaccgag
     3601 gcgagcgaag cgatggcgcc gctcttgtcg cggccgtgca tcgggttggc tcccggggcg
     3661 aaggccacgc ccttgaggcg tccgtcgggc gttgcgccgg tcttcttgcc gtacatcacg
     3721 ttcgaggtga tcgtcagcag cgacagcgtc gggcgggcgt tcttgtagac gggcagcttc
     3781 ttcagctcct cgctgaagta gtagacgagg tccacgccca ggtggtcgac acggtcgtcg
     3841 ttgttgccgt agcaggggaa ttcaccctcg atgtcgaagg cttcggtgag cccctcggcg
     3901 ttgcggcggg gcgtcacgcg ggcgtatttg atggccgaga gcgagtcgag ggcgatcgag
     3961 agaccggcca cgccgtaggc gagattgatg cggggatcgg tgtcgacgaa tgccatctgg
     4021 gccttctcgt agtagtactt gtcgtgcatg tagtggatga tgttcatggc ctcgttgtag
     4081 acgcgggcga tctccttgag caccatcttg tagttgcgca tcacctcttc gaagcgcagc
     4141 ggaccctccg acagcgccgg aatgcccttg accatcagcg tgccggtgtt ctcgcagcga
     4201 ccttcgttaa tggccagcag cagggccttg gccaggttgg tgcgggcgcc gaagaactgg
     4261 atctggcggc cgatgtcctg gaacgagacg cagcaggcga tgccgtagtc gtccgagtgg
     4321 cgcacttcgc gcatcaggtc gtcgttctcg tactggatcg agctggtgtc ggccgaaacc
     4381 ttggcgcaga agtccttgaa tccctgcggc agctcggggc tccagagaat cgtgaggttc
     4441 ggttcgggcg aaggaccgag gttgtagagc gtttgcagga agcggaacga ggtcttcgtc
     4501 accttcgtgc ggccgtcgtt gaagcgtccg ccgatggcct cggtcaccca cgtcgggtcg
     4561 ccggcgaaga tgtcgttgta ggactgcatg cgcaggtggc gcaccatgcg cagcttgatg
     4621 acgaactggt cgatcagctc ctgggcgaac gactcgtcga tcgtcccgtg cgcgaggtcg
     4681 tattcgatga agatgtcgag gaacgacgat acgttgccca gcgacatggc ggctccgtcc
     4741 tgctccttga cggcggccag gtaggccatg tagacccact gcacggcctc ctgcgccgaa
     4801 tgcgccggac ggctgaggtc cagtccgtag tattcgccca tcgtgcggat gtccttcagg
     4861 gccttgatct gctcggcgac ctcttcgcgc aggcggatgc gggcgtcggt catcgggccg
     4921 gtgaggttgc ggaggtcctc ctgcttggcc tcgatcaggc ggtcggttcc gtagagggcc
     4981 agacggcggt agtcgccgat gatgcggccg cgggcgtagt tgtcgggaag acccgtcagg
     5041 aagcccagcg agcggaacga gcggatctcc tcggtgtaga cgtcgaacac gccgtcgttg
     5101 tgcgtcttgc ggtagtgggt gaagatgtcc ttcaccttct cgtcgacctc cacgccgttc
     5161 tccttgcagg cgcgcgatac gacattgatg ccgccgaaag gtttgatggc gcgcttgagc
     5221 agttcgtcgg tttgaaggcc cacgatcagc tcgttttcgc ggtcgatgta gccggccttg
     5281 tgcgaggtga cggtcgaaac ggtcttgttg tccagcgcgc ggacgccgtt atgctgacgc
     5341 tcctcttcga gggccttgag gcagaggttc cagatgtgct tcgttcgctc ggtaggtcct
     5401 gcgaggaacg aggcgtcgcc caggtagggg gtgatgtttg tctgtacgaa gctcgtcacg
     5461 ttgatctctt tgctccaaag cccgtcgata aaggttttgt tcagttccat agatgatatt
     5521 gttcgttttg agatgataat tgtcctattt cggtcggcaa agatacgtta tttttttcac
     5581 accggccaaa gagcggttac aattttttat aaaaatttaa aaaataccta cgatcaggta
     5641 ttgacggcgc cttccgggac atgcaatagt tacaggaagg cgttgcggcg tttgtggccc
     5701 tgcttttgca ggggcgggag tgtataaata cgaaaaacga tgaaaagatt ctggattgcc
     5761 ctgctgggtg cggggctttt tgcgacggcg gcgttcgccg gcggtgacga agttccggtc
     5821 aggatgcacg aactgcccga tgcggcgaag acgttggtga aaaagtattt tcacgacatc
     5881 gaggtggttt ccgccacgat ggagaagggc gtggccccga gctatgaggt gaagttggcc
     5941 gacggtacgg agatcgactt cgacgcccgc ggcgagtgga ccgatgtcga gcggccgggg
     6001 ggtgtcgtgc cggacgggct gattccgcag ccgatcctga aattcgtggc tgcgaactat
     6061 ccggggcggc acgtccgggg tgtcgaacgc gacggccgca accatgaggt ctccctcgac
     6121 aacggactgg aactgaaatt caaccgccgt ttccggctgg tggagaccga tcactgacgg
     6181 ccgacgattg gtgcggcgga ttacggcccg ggggtttgag ttgcgcatcc ggcccccggg
     6241 tcccgccgct ttgtaaggtg aaaggtgtaa gatgaaaggt gaatttttca tttacaacct
     6301 ttcaccttcg gctttgataa aaagcgtatc tttgcagcgt aaatcccgat aacgatggaa
     6361 gaactctcgc ttacgacccc cgccctgctg ttttcggccg tgtcgctgat tctgctggcc
     6421 tacaccaacc ggtttctgtc ctatgcgcaa ttggtgcgca cgctcaagga gcagcatttg
     6481 cagcacccct cgaaggtgac gcgcgcgcag atcgacaacc tccgccggcg gctccacctc
     6541 acgcgcacga tgcagttgct gggcgtcacg agcctgttcc tgtgcgtggt gacgatgttt
     6601 ctgatctacg tggggctgat gctgctttcg gcttatgtct tcggtgcggc gttgctgctg
     6661 ctggtcggtt cgctgggcgt ttcgatctgg gagattcaga tctcggtccg ggcgctggag
     6721 attcacctca aggatatgga gaacccgctt gacaagcggg attcggaata attgtccggt
     6781 cgtgttcaag ccgccctttt ttaagggtga tttagcgaag cggcatcttt tgacaaaaac
     6841 gaagatgccg cgacgtcgcg tcactgcatc tcccactaac ctacttatgt aacctaaaac
     6901 caacttgtga atccggttct ccggttttca cagtgcaaag atacgggtcc gtcgtttcgc
     6961 tgaaatgacg gacccgttgc attttcgtta cacggcgctt tttgaagctc tccttttcaa
     7021 aggagggttt gggtggattg tctgcacgat ggcgtatcgg cattattttt tggcctccag
     7081 aaaatattgc tgcgatttga gcaggttgcg cgactggagc atcatcgtct tcgtctcgtt
     7141 gaggatcgtg aggtagagca ccccggcgcg ggtgctgccc gacgggacgt cgttgatgcg
     7201 ccgcagctgg ctcttgatcg cctcgacgat cgtgtcgaag agcttgtcgc gcatttcgag
     7261 caccagatcg aggtccgaga aatccttcgt cgccagcatg tcgttgatct tgtcgaaaat
     7321 cgcctccacc tggtcgttca cgcgcatcag gtcgacgatc tgctccttcg acatgccctc
     7381 gtggttgttg tcgatgtgtt cgaatgccgg gcgcgtgatg tggatcaggg ccttggtcac
     7441 ctccgaaagg tagtccgtga cctgcacgta gaagtgcccc gtgtcgatgt cgcaccgttg
     7501 caggcggcgc agcgtcggca tgacgttgta tttgcggatg cgggcctcct cgaaaagacg
     7561 gttcgagtcg cgcaccatct ccttgagcac cttgcggttc tccttgaaga cggctaccag
     7621 cgtgcggttg tagatgcgcg tgacctcctg catcgtcgtg cagacctcgc cgatgcaggc
     7681 gcacagcacc tcgtcggggg tctcggccgt ttcgagcggc agcagggcct tttcggcctc
     7741 ctctttcagt ccgggcgtct tgaggtggct gcggacgagc agccaggcgc agagcgccgt
     7801 gagggctgcc acggcgatcc agccgcccca cagcagcagg gctgtcacgg ccagcgcgat
     7861 gaggaatcct ccgagcgccg tgatgaacca ccccgagatg acggccatca cgcccgtgat
     7921 gcggtagacg gcgctttcgc ggccccacga gcggtcggcg agcgacgatc ccatggccac
     7981 catgaagacc acgtaggtcg tcgacagcgg cagtttgtag gaggtggcga tggcgatcag
     8041 gatcgacgcg gcggtgaggt tgaccacggc gcggaccatg tcgtaggggg ccgacgaacg
     8101 ctcctcggca gggagcggct cgaaacgccg gtcgatggcc ttctgaaccc gcgccggaat
     8161 cagcccggtc cacatcgtgt tcatcaccag cgtcgcgcgc accagactgc gcgaaatgag
     8221 ggtcgaaccg aagcgttcgt cgccctcgtg ctgcgaggcg agcgacagtt cggtctcggt
     8281 gacgtgctgc gactttttcg agaagaacaa cgtcagcacc atgatcagtc ccgagacgcc
     8341 cagcagcagg aagttggccc gggcgggagc ttcgagcgcc cccatcatca tcgtttcgct
     8401 gcccgcctcg ccggcgatgc gccaggcgtc gtagccggcc agcggcacgc cgatgaagtt
     8461 caccaggtcg ttgcccgcga aggcaagggc cagcgagaag gttcccgaca ggatcgtgat
     8521 gcgcatgatg ttgagccgca tgcgctggaa aatgtagagg aggagcgacg ccgcggccca
     8581 gaaggcgagg agcgtcacga ggacgtggtc gccgacgtag gccgaaacgg aggtcgggat
     8641 cagtcccgag cttttcaacc ccttgaacag cgcgaaatag aggattccgg ccagcgagat
     8701 gccgcaccag acggctcccc agcggcggaa gacggcggcg tagcggaacg agaagatgag
     8761 gcgcgaaatg tacatgaaaa gcgttccggc cacgaaggcc agcgccaccg acaacaggat
     8821 cgccgcgatg atgaccatgg ctttgcccgt gttgatgaac tgcgagaggt cctgcaagga
     8881 ggtccccggg tcgccggcga tgcggaacag ggcggcggcg acggcggcgc ccagcagacc
     8941 gaagaccatc gacacggtgg tcgaggtggg cagtcccagc gtgttgtaga ggtccagtag
     9001 cagcacgttg cccagcatca tgcccagaaa cagcatcata atctcctgaa aggagaactg
     9061 tccggggtag aagacgccgc tgcgggcgac ctccatcatg ccgctcgagg tgagcgtgcc
     9121 gaccagaatg ccggcggctg cgacccagag gatcacgcgg cgcggtgcga ctttcgagcc
     9181 gagggccgag ttgaggaagt tgacggcgtc gttggcgacg cccacgacga tgcccatcac
     9241 ggccagcagg gccaggatga cgacgattgc ggtgaatagc ggggacatgg attatccgtt
     9301 ttcgtaattg ttatggttct ttaccgttgc aaaggtccga aaccgatgtt acaaaggcgt
     9361 tacaggggcg ttgcggggga gtgaaaaaat atcggggagc ggtaaaaaac cgatccggcc
     9421 gcctgtccgg ccgcgtgcga caactgcagg cgacaggcga gcgcaatcgc ttgcgaattg
     9481 ccgggccgcc acagcagtca aggcgtgtgt ttttgcgcct taactccccg ccgaggcggg
     9541 gagtcagggg tggctccgat tcgtaatcgc agccaaaggc tgcgaatgcg gccgggcggg
     9601 ttgtcgtgta gctggaattt gttaactgtg tttcttcaat gtgaagacga actccagccc
     9661 gccgcgttcg cgttcgcggg ccgtgatcgt gccgccgtgg atcgcaacgg cgtttttgac
     9721 gatcgccagc cccagtcccg tgccgccctg tttgcgcgat cggcccttgt cgatgcggta
     9781 gaagcgttcg aagatgtgcg gcaggtgctc ctcgccgatg ccgatgccgt tgtcggcgaa
     9841 cgagaccgtg cactcttcgg gggtgtcgga aagcagccgg atgaagatgt cgcgtccgcc
     9901 ggaataggcc gcggcgttgt ccgcgaggtt gcggaatatt gatgtcagca gcgacgggct
     9961 gccgacgatc tcgacctgct gcgggaagtc gatgttcacc cgcagccgct ggtcggcggg
    10021 tttcagttcc atgtcggccg tgacttcggc gatcaggtcg ttcagcacga cgcgctcctt
    10081 ctggatcagc tggctcgcct cgtccatgcg cgtgatggtc gagatgtcgg ccagcagacg
    10141 ccgcagacgc tcggtctgtg cggcgctttt tttcaggaag tccgtgcgtc tttgcgcgtc
    10201 gagcgacggg ttggccagca gtgtttccag atagccctga atcgctgcca cgggggtctt
    10261 cagctcgtgg ttgatgttgt tggtgagctg tttcttgatg cgtattttct cctgttcctc
    10321 gtgcagcgcg agggcgtgct cgcggtcgcg gtcggcagtg gttttttgca gacgggcgta
    10381 gaggcggatg atgtggctcg atatttcgcc cagttcgtcg tgaggaaatg ccgggaggtc
    10441 gtcgatccgc tcgctccgct cggcccgttc ggcgaattcg ttcagccggg tgatgttctg
    10501 gcccaggcgg cgcgtggcga aatagcccgc cacgctcatc agcagcgtca cgcccagcat
    10561 gaaccagagg aattcgcggt cggtggccag gatttcaccc agcggcacgg agtagggtac
    10621 ggccgaacgg acgatgtagc ggtcgccccg catggccgag tagaaatagt tgcggtcggt
    10681 gctttcggag tggcggcgga tggtgtaccc cgtcccgcgg gccagcgcct cggcgacctc
    10741 ggggcggtca aggtggttcg cgccgggcag cgtgtcgagc gaattgtcga aaacgacgtg
    10801 tcccgccggg tcgatcagcg tcacgcgcac tccttcgcag ggtgcgccgg agcgggcgat
    10861 gaaggcgtcg gggggcgcgc ccgcattcac ggcgtcgagc atccgcaagt tgaaaagctg
    10921 caactgcgcg tcgagccgct cggccttgaa gtgcttttcg cgcccgtact ggaaaaggat
    10981 gaaacacccc accagcgtcc acgaaaagac gagcagcagc aggaacagcc gccggtggta
    11041 ggaaagttta tgcttcaaag ccgtagccat agcccaggcg cgttacgatg tgttccccgt
    11101 aaggcccgac tttacggcgc aggcgtgtga tgttcacgtc gaccgtgcgg tcgaggacga
    11161 tcacctcgtc gctccagatg cggcgcagga tctcctcgcg tgaaaagatc acgccccggt
    11221 tcgagagcag cagagccagg atttcgaact ccttcttggt gagttgcagc tccttgccgt
    11281 cgagcgtgca gactttgcgc cggaggtcga tctccagacc ttcgaagcgg atgctttcgg
    11341 attcggcgcg tgcggcggac gtgcggcgca gtacactgcg cacgcgggcc agcacttcgc
    11401 ggaccgaaaa gggtttggtg atgtagtcgt cggctccgat gttcagcccg gccaccgtgt
    11461 cgtcctcgga gtccttcgcg gtgcagaaga tcacggggac ccgggccgtt tcgggatcgg
    11521 ctttcaggag ctgcgccatc cgaaagccgc tcatctcgcc catcataacg tccagcagga
    11581 tcagcgaata gcgttcggga tgcatccgga gggcctgctc ggcgctgtat gccacgtcgg
    11641 cttcgtagcc ttcgacttcg aggttgaatt gcaggatttc gcacagcgac tcttcatcgt
    11701 cgaccaccag gattttgtgt tttgccataa atgcgggttt gagtccgcag caaatttacg
    11761 catcattcac cgatgttgca tgcccccggc atgacattta accgaaatgt aatgttgtct
    11821 catgcgcttt tgcggtcaag aagcgcaggg ggcctttgcc ggatgcctgc aaaaaaccga
    11881 aaaggccccc ggcggccggg agcctttcgt gtcgggcgac gcgggaaaac ctatttcccc
    11941 agcacctcca tctgctggcg gatcgactcc tcgtggatgg cctgcaggac ggtgcgcatg
    12001 aactcgcggt ccatgcccat ctgcccggcc tgcccggcgc ggcgggccag cagctcctcg
    12061 taacgctgcg tttgcaggac gggcatgttg tgctcctttt tgtactgtcc gatgtcgcgc
    12121 gagacgcgca tgcggcgcga gagcagctcc agcagctggt cgtcgagctt gtcgatctgc
    12181 gaacgcagtt cggtgaggct ctcggtggtg atcgactcgt cgcggatcac caggttgcgg
    12241 atgatatagg ccagcgcctc gggggtcacc tgctgggcct tgtcgctcca ggcgcagtcg
    12301 ggcgagcagt gggcttcgat gatcagtccg tcgaacccga ggtccatggc ctgctgcgac
    12361 agcggggcga tcagctcgcg cttgcctccg atgtggctcg ggtcgcagaa gatcggcagg
    12421 cgggggaggc ggcggtgcag ctcgatggga atggcccaca tcgggtggtt gcggtagagg
    12481 ctcttgtcga tcgacgtgaa cccgcggtgg atggccccga tgcggcggat gccggcgttg
    12541 tagatgcgct cgatggcgcc gatccacagc tcgaggtcgg ggctgacggg gtttttcacc
    12601 agcaccggga cgtccgttcc gcgcagggcg tcggcgatct cctgcatggc gaaggggttg
    12661 gccgccgtgc gtgcgccgat ccacagcagg tcgacgccgc ctttcagcgc cgtggcgacg
    12721 tgctcgcggg tggccacttc ggtcgaggtg tacatgcccg tttcgcgttt cacgcgctgg
    12781 agccaggcga tgcccgcctc tccgacgcct tcgaagccgc cgggtttggt gcggggcttc
    12841 cagagtccgg cgcggcagat gcggatgcct tcggctgcca gcgagcgggc cgtgtcgagg
    12901 acctgctctt cggtttcggc gctgcacggg cctgcgatta ccagggggcg ccgggggtcg
    12961 attcccggga gtgtgatggg ttgaatgtcg ttcatggttg cgttattttt gtttgttttt
    13021 ttagtgtctt tcctttttcc ggctgcttgc ggtgcgcggc gttccggggc gtcagatcgc
    13081 ggggttgggg cattcggcgt attcgccgag aatgcggaag tcgctggtga gaggccgtgc
    13141 ggcgtcgatg gcctgccggt aacgcatcgg gtcgtcgaac gtcacgtcga cgtagaagcg
    13201 gtattcccac tcgcgcccga tgatgggcag cgactgtatt ttggtgaggt tgatgtcgta
    13261 gaacgagagg acggtgagca ccttggagag gctcccccgg gtgtgcggaa gggtgaagag
    13321 cagagaggct ttgtcggtgt gggcgggatc ggcgaattcc gcggcgcggc gctcgtcggc
    13381 gagcaggagg aagcgtgtga agttgtgttt gttggtctcg atgccccgcc ggaggatttc
    13441 gagtccgtag agacgggctg cgtcggcgcc gcagatggcc gccgtgcctg cgaggcgtcc
    13501 ctcggcgatt tcgcgcgcgc tgcctgcggt gtcgtccctt tcgacgatct tcatgccggg
    13561 gagggttttc aggaaatcgc cgcactgcat cagggcgatc gggtgcgagc ggacttcggc
    13621 gatgtcgtcg ggcgtctgcc cggggagggc cgccaagacg tgcgagatgc ggagtttctg
    13681 ttcgccgatg atccgggcgc ggctctgttg caggagctcg tggttgggca gcaggctgcc
    13741 ggcgatggtg ttttcgatgg ccgcgatgcc cagcagcgcc ggatcggcgg ccatccgggc
    13801 gaacaactcg tcgaaactca agcagggcag cacctctatt tcccggtctg cgaaatagcc
    13861 gcgcgccgcc gtttcgtgat agcatcctgc gatgccctgt attgcgattt gttccataat
    13921 ggtttgaaaa agaaaatccc gctcaaccga gcgggatttt cgtgtcatat taatctatac
    13981 tatctgtata cagttaattg catgcgatcc cgctttttcc cttgctataa aagaaaaagt
    14041 aataaaaata gtatgcaaaa ccgtatgctc tcatcattcg atggctttta tcgttggcaa
    14101 atgtagcgaa ataatccgta aaaccaaacg tccgccgtat tttttttgcg aaaaaatcag
    14161 cccttgcggt gccggaaccg cttgcgcaac tgcttgcggc ggccgaacgc cagccggaag
    14221 aaggtcccgc gcagcagcgt gtcgtcgaca tcccatccgc gcgtttcggc gtagcggtcg
    14281 aggatgtaga ggaatgccac ggcggggcag gacaaccgcc ggaggttgat catgcaggcc
    14341 cgggaggaaa ggggccggtc gtcgaaatgc atgcggttga tgtcgatcag ctggaagcgg
    14401 taggcgcccg cgggggtgcg gtcccagagg atgttgccgt ggttgaagtc ccggtgctcg
    14461 atgcctttct cgtggagctg cacggtgaag cgggcgaagg cctccagcac gggcagggtc
    14521 cccgctgcgg ggaagcgtgc ggtggtctgc gacagcgggg tgtagtcgga gcgccgcgag
    14581 acgtagtagc tgtcgcagag cagtccgcgg cggcggtatt cgctccatgc gacgggttcg
    14641 ggcgaatcga cgcccagcgc ccggagccgc acggcgtgtt cgtacgagcg gcgggccttg
    14701 ctccggcgga agaaggtgta gatgacggcc cgcagcaggt tcgggcgctt gaaccgtttg
    14761 acgaccagcc gttctccctc cgcctcgaag gctttgatcg tgttgcgtcc cgcgtgcagg
    14821 acctcgcctt cccggtcgaa gagttcgggc aggcgttccg cgaagtcccg caggtgttcc
    14881 gaggccgtat tgacgtgaat gtgcattgcg gtgttttttc tgtagcaaag gtacgcaccc
    14941 gcggcgtaag gcgttagtcc tgtttgattg ttaagttgtt ctgaaacgga aaagaaaggc
    15001 ggatttcatc gggtggcgtg cggagaacgc gctccttttc cccgaaggcc gggtgcggtt
    15061 ccggacgggc atgaaacgag cggaactttt tccgctcgtt ttcgggattt atctcatccg
    15121 gatgtggaac gctttggggc gtgtcatcgt cttcgtggag gtgcggccga acgagtcggc
    15181 gacttcgatg cggacggtcg tcgcaggtcc cgaggcgcgg taacgccaca tgtgggggtt
    15241 gcaggccgtc tggaacggtc tggtgccgcg catgtaggtg atcttgtgca gccgaaatcg
    15301 ttgggcgtga ccggtctccg ggcgaagccc tcggccgcgg cggccgtcgc cagcgacagc
    15361 gcgcagcacc ggtttttcgg aaacgggttt ccgtggggcg cgttatttcg aagaggggtc
    15421 gaatacgaag atgttctggt agtgtttcgt attgtcggcg gtgattccgc gggccgtgta
    15481 tcccaggtag agcttgtcct tgcagacctt
//
