LOCUS       c00053_gnlPro..        13754 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHMINLCA_53.
ACCESSION   c00053_gnlPro..
VERSION     c00053_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:15:54
            Original ID  :: gnl|Prokka|FHMINLCA_53
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3088
            Orig. end    :: 16842
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13754
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13088:16841]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13753
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13754
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13754
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1306..2844
                     /locus_tag="ctg53_3"
                     /transl_table=11
                     /translation="MLKIRIAIPFAGLALTACGQSEAGRPNVIYVFPDQYRNSSLGFWS
                     DPEFAAEVGWKGDPVATPNLDRFAREATVLTEAVSNFPVSSPHRGMLLSGMYPERNGVV
                     LNCMSERPESSLREDVECIGDVFSAAGYDCAYIGKLHADFPTKNNPQRPGTYVSDAVPE
                     WDAYTPPERRHGFNYWYSYGTYDVHKHPHYWDTDGNRHDVDEWSPRHEVSKAIEYIENK
                     GGVRDPEKPFLMMIGMNPPHSPYASTDDCDLEGYERYKDKSLTELLVRDNADTTMAKAA
                     AVRYYFANVSGIDREFGRLLAALDRAGLTENTIVVFASDHGETMTSHSTDDPKNSIWRE
                     SLNIPFLVRYPGRVPHRVDDLLLSTPDIMPTLLGLAGLGERIPAGVEGRDYSAVLRQDA
                     VQPERPRAALYMRNLDGGRDADGLVRGFFAQARGVKTATHTMELRIDRDGTLERVLMFD
                     DAADPYQLHNLAPEEHPALFAALCRELAVLLRDNDDVWFREGVLSDVVPYDTNN"
     CDS             2858..5434
                     /locus_tag="ctg53_4"
                     /transl_table=11
                     /translation="MNKLFLWIAAASAFVLQSCENTDGIRDEIGSLRDRVIALEAKIGS
                     VNTSIVALHKLMDESTIIVGIEPNAKGYEIELSDGTRLPVILGEKIEALVPVMGIDAEG
                     YWTVSLDGGATSERLKVGGEYVSAWPVSGGDHRPGAEGVTPQLKVSADGEWLVSLDGGA
                     TYAPLLQNGQPVNALGDKVVVSYSSAFKSVTYDATTGLLAVELLDGEKLTLPVFDDFGL
                     TVTASDNETFRLGETRAFEVVQNNVAEAVIDAPAGWTAVLGETTLTVKAPATFDAASQQ
                     AAVSVTVYSDRKYRKLVTLNVTLLDEQVDANAALAWRNFKAGTADNVLLDYSYAGYKHG
                     EEAPADVWGLGYKVYNVVDYGADPTGVRSSRGALAALLKELKLSGRSDAGANLANANAR
                     AVIYFPEGRFVLHNDDDNVVDPTSANQKYTDSKGNNRSEEIFIRGGYFVLKGAGRGKTT
                     LVMDTPNLPNNSEQMWSSPMMINIKHNSGLSDLTTVTGDAARGTFSVEVASAAGIGKGD
                     WVCLSLSNNDPTLVAQELAPHRVEGNMTDIQTITVEDYHQVASVSGNRVTFAEPIMYAV
                     EAKWGWKIRKYPHYEHVGVEDLTFEGRSKENFGHHASWEDDGAYKPLNMMRLTDSWIRR
                     VDFRGVSEALSIVSSANCSAYDIEISGNRGHSGVRSQSSSRIFIGKVCDRSRGQAVSPP
                     YTSTGYFENAGQYHASGVSNTSLGAVLWNNTWGDDAFFESHSRQPRATLVDRCTGGFVQ
                     WRFGGDETNVPNHLGDLTIWNLNATRAAHDFGAEPFKWWLSSDKWWKTMPPIIVGFHGA
                     AVTFDESAEQVKYLESNGAAVEPLSLYEAQLRQRLGYVPAWLNSLK"
     CDS             5455..7704
                     /locus_tag="ctg53_5"
                     /transl_table=11
                     /translation="MKKYLILIFVALAAVFQSCDNNDDLWDAIDDLKSRVQALETQVDA
                     LNGNIEALQKLYGGATISKVETSDGKYVVTLTNGETIELVQGSEAEAVIPIVSINDKGE
                     WQVSTDNGATFTSLGVKAVAEDGTTPRFRIDEATGYWQVSYDGGTSFENVKDTKGQPVK
                     AIGSGTVTDKFFEEVKVDGGDLYIRLLGGEELRIPIVNDFFCRIVTPTEGVQTFDAGAT
                     KRFVVEIRGVEQVKLSAPEGWSARLTDAVDERAELIVTAPAAVTRATADTSKDVAIEAF
                     AAGGLSTVAKIQVESTGTAPAAPTVAVTNSATVEPTQSALTFDVAPSANADGWKYLCLK
                     STEAAPDAARVLAEGTAGAGTGVTVRNLEANTAYTIYVVAYAGDLTSEVASVGNTTAEA
                     PVTAETDYYQDYQDGKDIALGDLTINKTVYPEAQLLKPSELTAAIITAGGLIFVDNSDA
                     ADLSFTISGASINMGDIVLIGRYPERAQATISGPELRCKYNAAFKNLHIAASGNYNLFT
                     TTNATYDPTLHVEDCTVDAAYNVVYDSHNTQNFKSVYFGNSIVKMTVANKPFYSTKAKD
                     AHTQQLIRLDNNVFYAETPLQNYLINCGDRSQAFQTTRLQVEVTNNTIYNIYQPNIMIR
                     AYVLAGLTVTKNVGYYTGVTAKNYLTGVYDTAGFTADKAEVTYNYLYTAPVSDTNFWSA
                     KHTGSYTPANNQMGDGVEAPFSSMDAAKGYFPVDASVVKTGAGATYDTKAWFKAE"
     CDS             complement(7782..8747)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PMI_typeI"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_6"
                     /sec_met_domain="PMI_typeI (E-value: 1e-13, bitscore: 40.7,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKFQPILKSLIWGGEKIAPYKGIATDQRNIGESWELSGVKDNES
                     VVAEGPEAGTSLPELIARHGAALLGKANYGRFGEEFPLLIKFIDARQDLSIQVHPNDEL
                     AWERHKSKGKTEMWYVVSADKDAHLRSGFSKQVTPAEYEASVGDNTITDILADYKIAPG
                     NVFFLPAGRVHSIGAGSFIAEIQQTSNITYRIYDFNRRDANGNTRELHTELAKGAIDYT
                     VLPDYRTHYEPAQDTRVELVSCPYFTTSLYDLTRPETLDLASLDSFVVAICIEGRGTLT
                     DDSGAAVPVHQGETVLIPASARSLAFTPDGGMKILTSWIG"
     CDS             complement(8760..9866)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_functions="other (smcogs) SMCOG1034:Repressor, ORF,
                     Kinase (Score: 71.3; E-value: 3.1e-22)"
                     /gene_kind="other"
                     /locus_tag="ctg53_7"
                     /sec_met_domain="ROK (E-value: 5.4e-23, bitscore: 71.3,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSHDNRVVITLDAGGTNLVFGAMQANKFIVEPITLPSHAENLDK
                     CLATMVEGFQAVIDRLSEKPVAISFAFPGPADYPNGIIGGYLPNFPSFREGVALGPFLE
                     AKFGIPVYINNDGDLFAYGEALGGALPEVNARLEALGSPKKYKNLVGYTFGTGLGVGLV
                     IDNRLNRGDNSCVETFCLRHKKMPEIIVEDGASIRAVKRVYGEASGDVNHTFEPKDICE
                     IAEGKRPGDVEAAKKAFAEMGEIAGDAMATAVTLVDGLIVIGGGITAARKWIMPSLLNE
                     LRSKMHQLNGNELNRVQMKVYDLDDETEFREFAKGAQRPLKVYGTDRYVAYDPQKRIGV
                     TISKLGASQAISVGAYAFALSQLDTENA"
     CDS             complement(10001..11047)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_8"
                     /sec_met_domain="IlvN (E-value: 8.6e-47, bitscore: 148.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.8e-46, bitscore: 145.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKINFGGVEENVVTREEFPLEKALETLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFRVIVGQREGSASWDKAVADGWVPGQTLFGIEEAAERATIIQYLLSDAGQI
                     AVWPSIKKHLTPGKALYFSHGFGITYKERTGIVPPADVDVILIAPKGSGTSLRRMFLQG
                     RGLNSSYAVFQDATGRAFERVVALGIGVGSGYLFETDFKREVYSDLTGERGTLMGAIQG
                     IFAAQYDTLRANGHTPSEAFNETVEELTQSLMPLVSENGMDWMYANCSTTAQRGALDWW
                     KKFRDATKPVFEELYREVAAGNEAQRSIDLNSKPDYREKLNEELREMRESEMWQTGAVV
                     RKLRPENN"
     CDS             complement(11086..11637)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_9"
                     /sec_met_domain="ALS_ss_C (E-value: 2.1e-19, bitscore:
                     59.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQEYIITVFSENKVGLLSQITTVFTCRDVNIESLTTSESALQGI
                     HKFTIVVRTTPDQVDKLVRQVEKKIDVLKTFVYTPDEVVQQEIALYKVTRSRGVEQLVR
                     EHNVRILEIDEDYIVVEKTGHKADTQALFRLLQPYGVQQFVRSGTVAIIKSRRELLNEY
                     LEEIDRLRAESDEEGSKSEK"
     CDS             complement(11651..13387)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_10"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.1e-47, bitscore:
                     149.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSQTLRPEERRTASDPSMTGSKALIESFLQEGVETVFGYPGGA
                     IIPVYDALYDYRDRLRHILVRHEQGAVHAAQGYARVSGRVGVCLVTSGPGATNTVTGLA
                     DALMDSTPLVLVTGQVGSALLGTDAFQETNFVGITQAVTKWNCQVKRTEDIPAAIAKAF
                     YIARSGRPGPVVVDITKDAQCGTAPFRYEKITSIRSYLPAPAPDAERIAEAARLINQSR
                     RPLVMVGQGVILGNAETELRALLDKSGMPAASTLLGLSALPTDHPQNVGMLGMHGNYGP
                     NIKNQECDLLVAVGMRFDDRVTGNPAHFGANAKVIHLEIDPAEIGKIIPADVAVVGDVK
                     RSLPLITERIRKRDHSQWIAGFRACDQIEYEAVIRKAVHPAEGRIRMGEAVAAVARAYR
                     NDAVLVTDVGQQQMNAARYFGFRRTRSVVTSGGLGTMGFGLPAAIGAKLGAPDREVVLF
                     AGDGGLQMTIQELGTIFQSKIPVKIVLLNNSFLGMVRQWQELFYDRRYSFTEMVNPDFG
                     LIARGNGLSYRCVERREELDEVIAAMKASEGAFLLEVRVEGEENIFPMVPAGAPVSEIR
                     FE"
     CDS             complement(13403..13753)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_11"
                     /sec_met_domain="ILVD_EDD (E-value: 1.6e-38, bitscore:
                     122.0, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TSYLKSKHLDKACALITDGRFSGGTSGLSIGHVSPEAASGGEIAV
                     VRTGDEIEIDIPGRSIRLAVDDAEIAARMAAQERFRPAGRDRRVPASLRAYARLVSSAD
                     KGAVRIVDDNEE"
ORIGIN
        1 cccgaacctt cgcctgcggg gaaccgcgtc tacggctaca atgcctcggt gtcgcaccgg
       61 cgcgccgact ggctggtgac cgtcgcgggc cacagccgct atctctggtc ggcggagatt
      121 taccagggag ccaaccacta cggtcgctac ctgacgcacg gcagcatgca gctgcttgca
      181 gacggcgatc ccgtgagcgc cttcggcagc gggttccggc aggagggctg ggactggcgg
      241 cacattcccg ggacgacggc gctcgaaatc ccgatggagc ggatgaaggc cgatatccgg
      301 aacgtcgaca ccgcgtcggg ctacgaggag atgctcctct ccgacgaggc cttcgccgga
      361 ggcgtcagcc acaggggccg cgacggggtg ttcgcgatgg aactccacga gcacgacaaa
      421 tacaacggtt cgctgcgggc gcgcaagtcg tggtttttct tcgacaaccg catcgtctgt
      481 atgggttccg acatcgaaaa caaggccgag ggcggtgtgc atacgacgct gttccagaat
      541 tttctggcgg acgcggccga tccgctcgtc gtgaacggcg aggcggtgac gcagttcccc
      601 taccgggccg aacttgcggg cggcgccgtc ctgcgcgaca acctgcgcaa cgcttacttc
      661 gtgccgaaag gtagggtagt cgtttcgaaa tcacttcagc gttcgctcga cgaggagacc
      721 gacgccccga cgcagaacaa tttcgcaacg gcgtggatag atcacggcag cgggtccgtc
      781 agcggcggcg ggtacgaata catgctggcc gtgcacgctt cggacgaaga ggcggtccgc
      841 tacgcgcggg aacttcccta cgaggtgctg cgccgcgacg cctcggcgca tatcctgcgc
      901 gacaggctgt cgggcattac gggctatgcc ctttttgcgg ccggtaaggt gggcgagggg
      961 ttgctggaaa gcgtttcgct gccttcgctg gtgatgatcg gcggggatgg cgaagggctg
     1021 acggtgagcg ctgcggaccc cgacctgcgt ttctacgagg ggccgagcga cgaggtgttc
     1081 gatgccgacg gcaggcgcgc cgagcggagc gtctactccc gcaagtggat cgacaatccc
     1141 tcgggagagt cgcagctgga ggtcgtgatc cgcggccgct ggcagtccgc agacgatagg
     1201 ccggagtgcc ggatcgaacc cgcgggcgaa aacaccgctt tgatcttcac gagccgcgaa
     1261 ggtgcgacgc gcgaagtgaa cctgattgaa atgaaataag acacgatgtt gaaaattaga
     1321 attgcaattc cgtttgcggg cctcgccctg acggcctgcg ggcagtcgga ggccgggcgc
     1381 cccaacgtga tctacgtatt tccggaccag tatcgcaact cctcgctggg gttctggagc
     1441 gatccggagt tcgccgccga ggtggggtgg aagggcgatc cggtcgcaac gcccaacctc
     1501 gaccgcttcg cccgcgaagc cacggtgctg accgaggcgg tgagcaattt ccccgtgagc
     1561 agcccccacc ggggcatgtt gctttcgggc atgtatcccg agcggaacgg cgtggtgctg
     1621 aactgcatgt cggagcgtcc cgaaagttcg ctgcgcgagg acgtcgagtg tatcggcgac
     1681 gtcttctcgg cggcgggcta cgactgcgcc tacatcggca agctgcacgc cgacttcccg
     1741 acgaagaaca acccccagcg tccgggaacc tacgtcagcg acgccgttcc cgagtgggac
     1801 gcctacacgc cgcccgaacg ccgccacggg ttcaactact ggtactccta cggcacctac
     1861 gacgtgcaca agcatcccca ttactgggat accgacggca accgtcacga tgtcgacgag
     1921 tggtcgccgc ggcacgaagt ttcgaaagcc atcgaatata tcgaaaacaa gggcggcgtg
     1981 cgcgatcccg aaaaaccgtt cctgatgatg atcggcatga atccgccgca ttcgccctac
     2041 gcttcgaccg acgactgcga cctggaaggg tatgaacgtt acaaggacaa gtcgctgacc
     2101 gaactgctcg tgcgcgacaa cgccgacacg acgatggcca aggccgccgc cgtgcgttac
     2161 tatttcgcca acgtgagcgg tatcgaccgt gagttcggcc gcctgctcgc tgcgctggac
     2221 agggcggggc ttacggagaa cacgatcgtg gtcttcgctt cggaccacgg cgagacgatg
     2281 accagccatt cgaccgacga ccccaagaac tcgatctggc gcgaatcgct gaacattccc
     2341 tttctggtgc gctatccggg gcgggtgccg caccgtgtgg acgatctgct gctctcgacg
     2401 cccgacatca tgccgacgct gctggggctg gcgggcctcg gggagcggat tcccgcgggt
     2461 gtagaggggc gcgactactc ggccgtgctg cggcaggacg ccgtgcagcc cgaacgcccg
     2521 cgcgcagccc tttacatgcg caacctcgac ggcgggcgcg atgccgacgg cctggtccgc
     2581 ggcttcttcg cccaggcgcg cggcgtgaag accgcaacgc atacgatgga gctgcgtatc
     2641 gaccgcgacg ggacgctcga acgcgtgctg atgttcgacg atgcggccga tccctaccag
     2701 ctgcacaacc tcgcgccgga ggagcatccc gcgctgttcg ccgcgctgtg ccgcgaactg
     2761 gccgtgttgc tgcgcgacaa cgacgacgtg tggttccgcg agggcgtctt gtccgacgtg
     2821 gttccctatg atacgaataa ctaacaatca atcggatatg aataaattgt ttttgtggat
     2881 tgcagcggcc tcggcctttg tgttgcaatc gtgtgagaac accgacggca tccgcgacga
     2941 gatcgggagc ctgcgcgacc gggtgattgc gctggaggcg aagatcggca gcgtgaacac
     3001 ctccatcgtg gcgctccaca agttgatgga cgagtcgacg atcatcgtcg ggatcgaacc
     3061 caacgcaaag gggtacgaga tcgagttgag cgacggaacc cggctgcccg tcatcctcgg
     3121 tgagaagatc gaggcgctgg ttcccgtcat gggcatcgac gccgagggct actggaccgt
     3181 gagcctcgac ggcggagcca cttccgagcg gctgaaggtc ggcggagagt acgtttcggc
     3241 atggcccgtt tcgggcggcg accataggcc cggcgccgag ggcgtcaccc cgcagctgaa
     3301 ggtttcggcc gacggggagt ggctcgtgag cctcgacggc ggggcgacct acgcgccgct
     3361 tttgcaaaac ggacagccgg tcaatgcctt gggggataaa gtcgtcgtca gttacagttc
     3421 ggctttcaag tcggtgactt acgacgcgac gaccggactt ttggcggtcg aactgctcga
     3481 cggcgaaaaa ctcacgcttc ccgtcttcga cgatttcgga ctgacggtga cggcttccga
     3541 caacgagact ttccgcctcg gggagacccg ggccttcgag gtcgtgcaga acaacgtcgc
     3601 cgaggcggtg atcgacgcgc ctgcgggctg gacggccgtg cttggcgaga cgacgctgac
     3661 ggtcaaggct cccgcgacgt tcgacgccgc ttcgcagcag gcggcggtct cggtgacggt
     3721 ctattcggac aggaaatacc ggaaactcgt cacgctgaac gtgacgctgc tcgacgagca
     3781 ggtggatgcc aacgccgctc tggcatggcg gaattttaag gccggaactg cggataacgt
     3841 cctgctcgat tattcgtatg ccggttacaa gcacggcgag gaggctccgg ccgatgtctg
     3901 gggactgggc tacaaggttt acaacgtcgt cgactacggc gccgatccca cgggcgtcag
     3961 gtcctcgcgc ggggcgttgg cagcgctgct caaggagctg aaactctccg ggcggagcga
     4021 tgcgggggcg aacctcgcga atgccaatgc ccgggcggtg atctatttcc ccgaggggcg
     4081 tttcgtcctc cacaacgacg acgacaacgt ggtggaccca acatccgcca accagaaata
     4141 caccgactcg aaggggaaca accgcagcga ggagattttc attcgcgggg gttatttcgt
     4201 gctcaagggc gcgggccgcg gcaagacgac gctcgtcatg gacacgccca acctgccgaa
     4261 caactcggag cagatgtggt cgtcgcccat gatgatcaat atcaagcaca attcgggact
     4321 ttcggacctc acgacggtga cgggcgacgc cgcacgcggc acgttctcgg tggaggtggc
     4381 ttcggcggcc ggcatcggga agggcgactg ggtgtgcctt tcgctttcga acaacgaccc
     4441 gacgctggtg gcgcaggagc tggcgccgca ccgggtcgag ggaaacatga ccgatattca
     4501 gaccattacg gtcgaggact atcaccaggt ggcttccgta agcggcaacc gcgtgacctt
     4561 cgccgaaccg atcatgtacg ccgtggaggc caaatggggc tggaaaatcc gcaagtatcc
     4621 ccattatgaa catgtcggcg tcgaggacct cacgttcgag ggccgctcga aggagaactt
     4681 cggccaccac gcttcgtggg aggacgacgg ggcctacaag ccgctcaaca tgatgcgtct
     4741 gaccgattcg tggattcgcc gcgtcgattt caggggcgtc agcgaggcgt tgtcgatcgt
     4801 gtcgagcgcc aactgctcgg cctacgacat cgagatcagc ggcaaccgcg gccactcggg
     4861 cgtgcgctcg cagtcctcgt cgcgcatctt catcggcaag gtctgcgacc gcagccgcgg
     4921 gcaggctgtc tcgccgccct atacgagcac ggggtatttc gaaaacgccg gacagtacca
     4981 cgcctcgggt gtgtcgaaca cctcgctggg ggccgtgctg tggaacaaca cgtggggtga
     5041 cgacgccttc ttcgagtcgc actccaggca gccgcgcgcc acgctcgtcg accgttgcac
     5101 gggcggattc gtgcaatggc gtttcggcgg cgacgaaacc aacgtgccca accacctggg
     5161 cgacctgacg atctggaatc tgaacgccac gcgtgcggcg cacgatttcg gggccgaacc
     5221 gttcaagtgg tggctctcct cggacaagtg gtggaagacc atgccgccga tcatcgtcgg
     5281 attccacggc gcggcggtca ccttcgatga gagcgccgaa caggtgaaat acctcgaaag
     5341 caacggcgcg gccgtcgagc cgctgtcgct ctacgaagcg cagctgcgcc agcggttagg
     5401 gtatgtcccc gcatggctca attcattgaa atagaataaa aaaccaaaca tattatgaaa
     5461 aagtatctga tcctgatctt cgtcgcgctg gctgcggttt tccagtcgtg cgacaacaac
     5521 gacgacctgt gggatgcgat cgacgacctg aagagccgcg tgcaggcgct cgaaacgcag
     5581 gtcgacgcgc tgaacggcaa catcgaggcg ttgcagaaac tctacggcgg cgccacgatc
     5641 tccaaggtcg agacctccga tggcaaatac gtcgtcacgc tgaccaacgg cgagaccatc
     5701 gaactggtgc agggcagcga ggccgaggcc gtgattccga tcgtctcgat caacgacaag
     5761 ggcgagtggc aggtgtcgac cgacaacgga gccacgttca cctcgctcgg cgtgaaggcc
     5821 gtggccgagg acggcacgac gccccggttc cgcatcgacg aggccaccgg ctactggcag
     5881 gtgagctacg acggcggcac ctccttcgaa aatgtgaagg acaccaaggg ccagcccgtc
     5941 aaggccatcg gctcgggtac ggtgaccgac aagttcttcg aggaggtgaa ggtcgacggc
     6001 ggcgacctct atatcaggct gctcggcggc gaggaactgc gcattccgat cgtgaacgat
     6061 ttcttctgcc ggatcgtcac gccgaccgag ggtgtgcaga cgttcgacgc cggggccacc
     6121 aaacgtttcg tggtggagat ccgaggtgtc gagcaggtga aactgtcggc tcccgagggc
     6181 tggtcggcac gcctgaccga tgccgtggat gagagggccg aactgatcgt gacggccccc
     6241 gcagccgtga cccgcgccac ggccgacacg tcgaaggacg tggcgatcga ggcctttgcg
     6301 gccggcgggc tttcgacggt ggccaaaatc caggtcgaga gcactggaac ggctcccgcc
     6361 gctccgacgg ttgcggtgac caactccgcg acggtcgaac ccacgcagtc ggcgctgacc
     6421 ttcgacgttg cgccctcggc caatgccgac ggctggaaat acctctgcct caaatcgacg
     6481 gaagcggctc ccgacgccgc cagggtcctt gccgaaggca cggccggtgc gggtacgggc
     6541 gtgacggtca ggaatctcga agccaatacg gcctatacga tctacgtggt cgcctatgcc
     6601 ggcgatctga cgagcgaggt ggcaagcgtc gggaacacga cggcggaggc tcccgttacc
     6661 gccgagacgg actactacca ggattatcag gacgggaaag acatcgcgct gggcgacctg
     6721 acgatcaata agacggtcta tccggaagcg cagctgctca agccctccga actgaccgct
     6781 gcgatcatta cggccggagg tttgattttc gtcgacaact ccgatgctgc cgatctgtcg
     6841 ttcacgattt cgggcgcgtc gatcaatatg ggcgacatcg tgctgatcgg ccgttatccc
     6901 gaacgtgcgc aggcgacgat ctccgggccg gaactgcgtt gcaagtacaa tgcggctttc
     6961 aagaacctgc atatcgcagc ctcgggcaat tacaacctct ttacgacgac caatgccacc
     7021 tatgatccga cgctgcatgt cgaggattgt accgtggatg ccgcctacaa tgtggtttac
     7081 gattcgcaca atacgcagaa tttcaagagt gtctatttcg ggaattcgat cgtgaagatg
     7141 accgtcgcca acaagccgtt ctattcgacc aaggcgaagg acgcgcatac gcagcagttg
     7201 attcgtctgg ataacaacgt attttatgcc gaaacgcctt tgcagaacta cctgatcaac
     7261 tgcggggaca ggtcgcaggc attccagacg acccggcttc aggtcgaggt gacgaacaat
     7321 acgatttata acatttacca gccgaacatt atgatccggg cttatgtcct cgcagggctg
     7381 accgtgacca agaatgtcgg gtattatacc ggtgttaccg cgaaaaatta tctgacgggt
     7441 gtgtatgaca cggccggatt tacggctgac aaggcggagg taacctataa ttacctctac
     7501 accgcgccgg tcagcgatac gaatttctgg tcggcgaagc ataccggaag ctacacgcct
     7561 gcaaacaacc agatgggcga cggcgtggaa gctccgttct cttcgatgga tgcggcgaag
     7621 gggtatttcc cggtcgacgc ttcggtggtg aagacgggtg cgggagcgac ctacgacacg
     7681 aaggcgtggt tcaaggcgga gtaattccgg cttgccgtaa cgaaaaactc cggcctgcat
     7741 tttcgcaggc cggagttttt tcgttgagcc gaagaggcgg atcagccgat ccagcttgtc
     7801 agaatcttca tgccgccgtc gggcgtgaag gcgagcgaac gggccgaagc cggaatcagg
     7861 accgtttcgc cctggtgcac cggaaccgct gcgccgctgt cgtcggtgag cgtaccgcgg
     7921 ccctcgatgc aaatcgccac gacgaacgag tcgagcgacg cgaggtcgag cgtctcgggg
     7981 cgggtcagat cgtagagcga cgtggtgaaa taagggcacg acaccagctc tacgcgcgtg
     8041 tcctgcgccg gctcgtaatg cgtccggtaa tcgggcagca cggtgtagtc gatggcgccc
     8101 ttcgccagtt cggtgtgcag ttcgcgggtg ttgccgttgg catcgcggcg gttgaaatcg
     8161 tagatgcggt aggtgatgtt cgaggtctgc tggatttcgg cgatgaacga ccccgcgccg
     8221 atcgagtgca cacgtcccgc gggcaggaaa aacacgttgc ccggtgcgat cttgtagtcg
     8281 gccaggatgt ccgtgatggt gttgtccccg acgctggcct cgtactcggc cggcgttacc
     8341 tgcttcgaga agcccgaacg caggtgcgcg tccttatccg ccgacaccac gtaccacatt
     8401 tcggtcttgc ccttggattt gtggcgttcc catgccagct catcgttcgg gtgcacctgg
     8461 atcgagagat cctgccgggc gtcgatgaac ttgatcagca gcgggaactc ctcgccgaaa
     8521 cgcccgtagt tggctttgcc caacagcgcc gcgccgtggc gggcgatcag ttccgggagc
     8581 gatgtcccgg cttcggggcc ttcggcgacg acggactcgt tgtccttgac gcccgaaagc
     8641 tcccagcttt cgccgatgtt gcgctggtcg gtggcgattc ccttgtaagg ggcgatcttc
     8701 tcgccgcccc agatcaggga tttcagaatc ggttgaaatt tatacatggt cgatctattt
     8761 tatgcgtttt ccgtgtcgag ctggctcaag gcgaaagcgt atgctccgac cgaaatggct
     8821 tggctcgcgc cgagtttcga aatggtcacg ccgatgcgtt tttgcgggtc gtaggccacg
     8881 tagcggtccg tgccgtagac tttcaggggc cgctgcgcgc ccttggcgaa ttcgcggaat
     8941 tcagtctcgt cgtccagatc gtaaaccttc atctgcacgc ggttcaactc gttgccgttg
     9001 agctggtgca tcttcgaacg cagctcgttc agcaggctgg gcatgatcca tttgcgggcc
     9061 gccgtgatgc cgccgccgat gacgatcagg ccgtccacca gcgtcacggc cgtagccatg
     9121 gcgtcgccgg cgatctcgcc catttcggca aaagccttct tcgcggcctc gacatctccc
     9181 gggcgtttac cctcggcgat ttcgcagata tctttcggtt cgaaggtgtg gttcacgtcg
     9241 cccgaagctt cgccgtagac gcgtttcacg gcacggatcg acgccccgtc ctcgacgatg
     9301 atttcgggca ttttcttgtg acgcaggcag aacgtctcga cgcatgagtt gtcgccgcgg
     9361 ttcagccggt tgtcgatcac aaggcccacg ccgagtcccg tgccgaaggt gtagccgacg
     9421 aggtttttgt atttcttcgg gcttcccagc gcttcgagcc gggcgttgac ctcgggcagg
     9481 gcgcctccca gcgcctcgcc gtaggcgaac aggtcgccgt cgttgttgat gtataccggg
     9541 atgccgaatt ttgcttcgag gaacggaccc agcgccacgc cttcgcggaa cgacgggaag
     9601 ttgggcagat aaccgccgat gatgccgttc ggatagtcgg ccgggccggg gaatgcgaaa
     9661 ctgatggcta cgggtttttc ggacagacgg tcgatgacgg cctggaaccc ttcgaccatc
     9721 gtcgcgaggc atttgtcgag gttctcggca tgcgacggga gggtgatcgg ctccacaatg
     9781 aatttgttgg cctgcatggc gccgaaaacg aggttcgtgc cgccggcgtc gagggtgatg
     9841 accacccggt tgtcatggct gtacatattg agtagttttg tttggattgc cggtgttccg
     9901 gcaggcaaag atacataaaa attgaacggg tgcaaaaccg aattgcgcga aaaaggccgg
     9961 cgactgctgc cgccggcctt tttcaggacc ttgccttgtg tcagttgttt tcgggacgca
    10021 gcttgcgcac gacggcgccg gtctgccaca tctcgctttc gcgcatctcg cgcagctcct
    10081 cgttgagctt ctcgcggtag tcgggtttgc tgttcaggtc gatcgaacgc tgggcctcgt
    10141 tgccggcggc cacctccctg tacagctctt cgaagacggg tttcgtggcg tcgcggaact
    10201 tcttccacca gtccagcgcg ccgcgctggg ccgtggtcga acagttggcg tacatccagt
    10261 ccatgccgtt ctccgagacc agcggcatga gcgactgggt cagctcctcg accgtttcgt
    10321 tgaaggcctc cgagggggtg tggccgttgg cgcgcagcgt gtcgtactgg gcggcgaaga
    10381 tgccctggat ggcgcccatc agcgtgccgc gctcgcccgt gaggtcggag tagacctcgc
    10441 gcttgaagtc ggtttcgaac aggtaacccg aacccacgcc gatgcccagc gccacgacgc
    10501 gttcgaaggc gcggcccgtg gcgtcttgga acaccgcata gctcgaattg agtccgcggc
    10561 cctggaggaa catgcgccgc agcgaggttc ccgagccttt cggggcgatc aggatcacgt
    10621 ccacatcggc cgggggcacg atgcccgtgc gctccttgta ggtgatgccg aagccgtggg
    10681 agaaatagag ggccttgccc ggcgtgaggt gctttttgat tgaaggccat acggcgatct
    10741 gcccggcgtc ggagagcagg tactggatga tcgtggcgcg ctcggcggcc tcctcgatgc
    10801 cgaaaagcgt ctggcccgga acccagccgt cggctacggc cttgtcccag ctcgcggagc
    10861 cttcgcgctg gcccacgatg accctgaatc cgttgtcgcg caggttgagc gactgtccgg
    10921 ggccttgcac gccgtagccg atgacggcga tggtctcgtc cttgagtgtt tcgagcgctt
    10981 tttccagagg aaattcctcg cgggttacga cgttctcttc gacgccgccg aaattgatct
    11041 ttgccatgat tttcgtgatt ttgagtttgt tatatgttct gaaagttatt tttcgctttt
    11101 gctcccttct tcatcggatt cggcccttaa acggtcgatt tcttcaaggt actcgttcag
    11161 cagctcgcgc cgcgacttga tgatggccac cgtgccgctg cgcacgaact gctgtacgcc
    11221 gtagggttgc agcaggcgga acaacgcctg cgtgtcggcc ttgtggccgg tcttctcgac
    11281 gacgatgtag tcctcgtcga tctccagaat gcggacgttg tgttccctga cgagttgttc
    11341 gacgccccgg ctgcgggtca ccttgtagag ggcgatctcc tgctgcacga cctcgtcggg
    11401 ggtgtagacg aaggtcttca gcacgtcgat cttcttctcg acctgccgca cgagtttgtc
    11461 gacctgatcg ggtgtggtgc ggaccacgat ggtgaatttg tggatgccct gcaacgccga
    11521 ttccgaggtc gtgaggctct cgatgttcac gtcgcggcag gtgaagacgg tggtgatctg
    11581 gctcagcagg cccaccttgt tctccgaaaa cacggtgatg atgtattcct gttccatacg
    11641 ctgtttcgtt ttattcgaac cggatttccg ataccggggc gcccgccggg accatcggga
    11701 aaatgttctc ttcgccctcg acgcgcacct ccagcaggaa ggcgccttcg gaggccttca
    11761 tggcggcgat gacctcgtcg agttcctcgc gccgttcgac gcagcggtac gaaaggccgt
    11821 tgccgcgggc gatcagcccg aaatcggggt tgaccatctc cgtaaaggag tagcggcggt
    11881 cgtagaacag ctcctgccat tggcgcacca tgccgaggaa cgagttgttc agcaggacga
    11941 ttttcacggg gatcttcgac tggaagatcg tgcccagctc ctgaatggtc atttgcaggc
    12001 cgccgtcgcc ggcgaaaagg acgacttcgc ggtcgggggc gcccagtttg gccccgatgg
    12061 ccgccggaag tccgaatccc atcgtgccga gaccgcccga ggtaaccacg ctgcgcgtgc
    12121 ggcggaatcc gaaatagcgc gcggcgttca tctgctgctg gcccacgtcg gtcaccagca
    12181 ccgcgtcgtt gcggtaggcc cgggccacgg cggcgaccgc ctcgcccatg cggatacgcc
    12241 cctcggcggg gtgcacggcc ttgcggatga cggcttcgta ttcgatctgg tcgcaggcgc
    12301 ggaatccggc gatccattgg ctgtggtcgc gtttgcggat acgctcggtg atgagcggca
    12361 gggagcgttt cacatcgccc acgaccgcca cgtcggccgg gatgatcttg ccgatctccg
    12421 cggggtcgat ctccaggtgg atcaccttgg cgttggcgcc gaaatgcgcg ggattccccg
    12481 tcacgcggtc gtcgaaacgc atgcccacgg ccacgagcag gtcgcactcc tggttcttga
    12541 tgttgggacc gtagttgccg tgcatgccca gcatgcccac gttttgcgga tggtcggtcg
    12601 gcagggccga gagacccagc agggtcgagg cggcgggcat gccgctcttg tcgagcagcg
    12661 cccgcagctc ggtttcggcg ttgcccagga tgacgccctg acccaccatg accagcggac
    12721 ggcgggactg gttgatcagc cgtgcggctt cggcgatgcg ttccgcgtcg ggtgcgggcg
    12781 cggggaggta gctgcggatc gaggtgattt tttcgtagcg gaacggagct gttccgcatt
    12841 gtgcgtcctt ggtgatgtcg accacgacgg gacccggacg gcccgagcgg gcgatgtaga
    12901 aggccttggc gatggccgcg ggaatgtctt cggtgcgctt gacctggcag ttccacttgg
    12961 tgacggcctg cgtgatgccg acgaaattgg tctcctgaaa ggcgtcggtg cccagcagcg
    13021 cggagccgac ttgtccggtg acgagcacca gcggcgtgga gtccatcagc gcgtcggcca
    13081 gccccgtcac ggtgttcgtg gcgccgggac ccgaggtcac cagacagacc ccgacgcggc
    13141 cgctgacgcg ggcatagccc tgtgcggcgt gcacggcgcc ctgctcgtga cgcacgagga
    13201 tgtggcgcag gcggtcgcga tagtcgtaaa gcgcgtcgta gacggggatg atcgcgcctc
    13261 cgggatagcc gaaaacggtt tcgacgccct cttggagaaa tgattcgatc agggccttcg
    13321 atcccgtcat cgaggggtcg gaggccgtgc gtcgctcttc gggacggagt gtttgagagg
    13381 tattcattgc gggtccgttt ttttattctt cgttatcgtc gacgatacgt acggcgcctt
    13441 tgtcggccga gctgaccagc cgggcatagg cgcgcagcga cgccggaacg cggcggtcgc
    13501 ggccggcggg gcggaagcgt tcctgtgcgg ccatgcgggc ggcgatctcc gcgtcgtcga
    13561 ccgcgaggcg gatcgagcgg ccggggatgt cgatctcgat ctcatcgccc gtgcggacga
    13621 cggcgatctc tccgcccgag gcggcttccg gcgagacgtg gccgatcgaa agccccgagg
    13681 ttccgcccga gaaacgcccg tcggtgatca gcgcgcaggc cttgtcgagg tgtttcgact
    13741 tgaggtacga cgtg
//
