LOCUS       c00059_gnlPro..        13092 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHMINLCA_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:15:54
            Original ID  :: gnl|Prokka|FHMINLCA_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13092
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13092
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[334:3092]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      335..3092
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13092
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13092
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             2..118
                     /locus_tag="ctg59_1"
                     /transl_table=11
                     /translation="TQDPNIKSVVLYQLSYGISVCQNENRFRFGGANVRIYF"
     CDS             335..1525
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_2"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.1e-39, bitscore:
                     126.6, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.8e-36,
                     bitscore: 114.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCKALIIGAGGVGTVVTQKIAANPVFTDVMLASRTKSKCDAVAAA
                     IGGNRVKTAEVDADSVPQLCELFRAFKPDIVVNVALPYQDLTIMDACLECGCNYLDTAN
                     YEPKDEAHFEYSWQWAYQDRFKAAGLTAILGCGFDPGVTAIFTAYAAKHHFDEIHYLDI
                     VDCNAGNHGMAFATNFNPEINIREVTQKGRYYENGEWVVTEPHEIHKPLNYPGIGERES
                     YVIYHEELESLVKNYPTIRRARFWMTFGQEYLTHLRVIQNIGMARIDPIIYNGVEIVPI
                     QFLKAVLPDPKSLGANYHGQTSIGCRIKGLKDGKERTYYIYNNCDHEQAFKETGTQAVS
                     FTTGVPAALGASMWAKGLWRGAGVFNVEEFDPDPFLAELGEQGLPWHELFDVNLEV"
     CDS             1953..3092
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_3"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 9.8e-12,
                     bitscore: 34.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDFLKLPSPCYVLDEELLDRNLATVDRVRRESGAEIIVALKACA
                     MWSIFPELAKHSDGATASSAAEARLVFEEFGRPAHTYAPVYTDSNIDEILNCSDHITFN
                     SLSQFRRFGQKALINGISCGLRINPQYSPVETDLYNPCVPGSRLGVTAEQLAAHGGLPA
                     GVEGLHFHVLCESRPEHLQKALEAVETHFGAYLDRIKWLNMGGGHLMTASWYDCDRLIA
                     LLKAFRSRHPNLRLILEPGSAFTWRTGFLVSTVEDIVENGGVTTAMLDVSFACHMPDCL
                     EMPYKPAVIGAHEPADGEKRWRMGGTSCLAGDYCGDWAFDRELKVGERVVFEDMIHYTM
                     VKTTMFNGVHHPAIVIARRDGRTDVIREFGYEDFRNRMS"
     CDS             3126..4427
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_4"
                     /sec_met_domain="PALP (E-value: 9.7e-27, bitscore: 83.6,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFTPTPYTLECVATGREFEDAGWMLADPQCKEPSLVRTKYARK
                     QIDVKPADWGLYRFSDWMPVRRILKGSSAPVTYKSKGLAAHLGLENLWITFNGWYPAIG
                     ATMSTCSFKETEAYSXXXVCGRAAADERRVLVVASAGNTARAFAKVCSDNNIRLLLSVP
                     YDNIGALWFDQPLNPCVKLISCEKGGDYFDAIHLSDIALKSPGFYAEGGAKNVARRDGM
                     ACTVLSAVTTIGRIPDYYFQAVGSGTGAIAAWEANMRLVEDGRFGRNTMKLMVAQNAPF
                     VPMYDAWQAASRKLLPYDDDKARRDAEIIDAKVLSNRRPPYSVTGGLFDALKATGGEVF
                     VATNAMARKARKLFHELEGVDIYSAAGVALASLVNAVNAGKIEKDATVMLNVTGGGEEH
                     FKEGKELWYLKPSHVFPLEPDENDVVEKVEALFN"
     CDS             4579..6561
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MENIQTKQYPCFKRWSRKNWSVFASLHRYVTIGVLSVGMSILLLA
                     TQGASAQTVDTTAVLKTLRIREVGVTGSQTAPARNAQSHTPLFDRKAQAPAPVQTLEAA
                     LRLAPSVDVRERGGKGTQADIFIRGGSFDQTMVLLNGIDFTDARTGHQSHALPVDLDCI
                     SAVELIDGVPGVGAYAGAVNIRTAPLRPTYLRLEASGGQYGYGYGNLSGAVSAGRFSVL
                     GAASYRRSDGYRHNTDFSNYNAFVRATYDGGRAGFFDLQAGWQDRDFGSNGFYAAYNPD
                     QWEHTATALGSLRWLKTAGRFSLGAAASYRKNFDRYDWTRGTAMNRHNTDNVGAKLWAD
                     CDWAAGVTTVGGDYAFNHIYSTNLGDKLSVPEGHYTHAKARHTGNLWLRHAKRWRHFDA
                     AASAGVSLTPYGTSALWSLSAGYAPAAGLRLEAGAWQSMRLPTFTDLYYTSPAQINNLD
                     LTPEHAVTYRLGVDYLKRSWNLSAQAYYRSGRDIIDWVWREDMGSKWHSEQTSSLDTFG
                     IELAGGYTVSEGFLRRVTLSYGYITTDRNADVIAKSAMDFMRHKAALAVEVHFLRRMSL
                     ALTGSVYDRNGSYTHYPEPGNASLNEERDYKPYFLLDGRLQWEKGICRLYVDATNITDT
                     RYCDIGGIRLPGFWCTGGVTLTIGK"
     CDS             6757..8457
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTCD_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="FTCD_C (E-value: 2e-65, bitscore: 209.5,
                     seeds: 242, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQRIIECVPNFSEGRDKAVIRQITAAIEASGGVKLLDVDPGEAT
                     NRTVVTFVGEPEAVVEAAFAGVKRAAELIDMRRHKGAHPRMGATDVLPLIPIAGVTLAE
                     CAELARALARRIADELRIPTYCYEAAAFAPERKNLAVCRAGEYEALPEKLAHTASAPDF
                     GVRPFDEGVARTGATTVGARDFLIAVNFNLNTTSTRRANAIAFDVREKGRPVREGNPIT
                     GRVVKDAAGNPVMQPGTLPATKAIGWFIEEYGIAQVSMNITDISRTPLRAAFDEVCRKA
                     DARGVRVTGTEIVGLVPKRALVEAGKYFLRKQRRSTGVAEEEIVRIAVKSMGLDDLKPF
                     DPAEKVIEYLLEAEVPKKRLIDMTCKAFAEETASESPAPGGGSIAAYMGALGAALGTMV
                     ANLSSHKAGWDDRWEEFSDWAERGQAVLAELLHLVDEDTAAFNRIMAVFAMPKSTDEER
                     AARAAALQEATLYATVVPLRTMKAASRVFEIVRAMASEGNPNSVSDAGVGALAARSAVL
                     GACLNVKINAAGLKDRAVADALIAEAEALAAEAVRLEAEVLQIVESKIG"
     CDS             8459..10498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Urocanase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_7"
                     /sec_met_domain="Urocanase (E-value: 5e-91, bitscore:
                     293.5, seeds: 148, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_C (E-value: 3.6e-91, bitscore:
                     293.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Urocanase_N (E-value: 5.2e-61, bitscore:
                     193.6, seeds: 71, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTREEFQNDIRAGIPDRLPAAKPYDKRINHAPKRKDILSDEEKAL
                     ALKNALRYFPVRHHAVLAKEFAEELRRYGRIYMYRLRPDYEMHARPIGEYPARCRQAAA
                     IMLMIQNNLDPRVAQHPHELITYGGNGAVFQNWAQYRLAMQYLSEMTENQTLVMYSGHP
                     LGLFPSHPDAPRVVVTNGMVIPNYSKPDDWERLNALGVSQYGQMTAGSYMYIGPQGIVH
                     GTTITVMNAARKRFTAGRTDTRGMLFVSSGLGGMSGAQPKAGNISGVVSVVAEINPKAA
                     QKRHEQGWVDELHEALDELIPRIRQAVKAKEVVSMAYVGNVVDLWERLAAEEIPVDLGS
                     DQTSLHNPWAGGYYPVGLSYEASNKMMAEEPGRFRECVQESLRRQVDAINKLTDRGMYF
                     FDYGNAFLLEASRAGAAVTGEGGRFRYPSYVQDIMGPMFFDYGFGPFRWVCTSGKPEDL
                     ETTDSLAAEVLEEIRKTAPDDIRGQLDDNIHWIREAGRNRLVVGSQARILYADCEGRVK
                     IAEAFNRAIAEGRITAPVVLGRDHHDVSGTDSPYRETSNIYDGSCLTADMAVQNVIGDA
                     FRGATWVSIHNGGGVGWGEVINGGFGMVIDGSEDAGRRIREMLLWDVNNGIARRSWARN
                     EGAVEAIRREMDRTPGLRVTLPVFADEKLVREALNEQGGASDKL"
     CDS             10530..12011
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_aromatic"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_8"
                     /sec_met_domain="Lyase_aromatic (E-value: 1.4e-189,
                     bitscore: 620.0, seeds: 479, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHHHITAEHLSVGRVREILERRLLLALSDDARARIVRCREYLDR
                     KMENPERPIYGITTGFGSLCDISVGRDELSRLQQNLVMSHACGTGERVPSEIVRLILLL
                     KIQSLAYGHSGVQLATVERLVEFFNRGILPVVYQQGSLGASGDLAPLAHMSLPLLGLGE
                     VEYKGEVRPSAEVLAELGLEPIRLQSKEGLALLNGTQFMSAYGVWSLIHARRLSEWADR
                     IGALSLDAFDGRIEPFCDEVHLIRAHRGQLATARNVRGLLEGSELIARPKHHVQDPYSF
                     RCMPQVHGASKDTIDYVESVLTTEINSTTDNPTVFPEGDMVVSAGNFHGQPIALAMDFL
                     AIALAELGNISERRTYKLISGARELPKFLVANPGLNSGFMIPQYTAASIVSQSKGLCMP
                     ASVDSIPSSQGQEDHVSMGSNAATKLWRVVCNTERVLAIELFNAAQAIEFRRPAHTSPE
                     LERMLADYRKEVPFIDNDEVMYPHIEASVRFLRGL"
ORIGIN
        1 aacccaggac cccaacatta aaagtgttgt gctctaccag ctgagctacg gaatctccgt
       61 gtgccaaaat gagaatcgtt tccgttttgg tggtgcaaat gtacggattt atttttaaaa
      121 tccaataccc ggcctgcaaa ttttgcgcaa aagtgtgttt tttgcctttc cggctgccgg
      181 atgccgcctg caggcgatag gcgtccgggc atcttccggc ggtttcggcc ggccgggatc
      241 gtgaaatttg gcgcgcggat tttgttttgc cgaaataaaa ggatattttt gtaggcgtta
      301 agatgaaatc taacttttaa aaccgaataa ttctatgtgt aaagcgctga taatcggagc
      361 cggcggcgtc ggaacggtgg tgacgcagaa aatcgcggcc aatcccgtct tcacggacgt
      421 gatgctggcc agccgtacca aatccaaatg cgacgccgtt gcggccgcca tcggcggcaa
      481 ccgcgtgaag accgccgagg tcgacgccga cagcgtgccg cagctgtgcg aactgttccg
      541 cgcgttcaaa cccgacatcg tggtcaacgt ggcgcttccg taccaggatc tcacgatcat
      601 ggacgcctgc ctcgaatgcg gctgcaacta cctcgacacg gccaactacg agccgaagga
      661 cgaggcgcat ttcgaatact cgtggcagtg ggcctatcag gaccgcttca aggccgcggg
      721 actcacggcg atcctcggct gcggtttcga cccgggcgtg acggccatct tcacggccta
      781 tgccgccaag caccatttcg acgaaatcca ctacctcgac atcgtcgact gcaacgccgg
      841 caaccacggc atggctttcg ccacgaactt caaccccgag atcaacatcc gcgaggtgac
      901 ccagaaaggg cgttattacg agaacggaga gtgggtggtg accgagccgc acgagatcca
      961 caagccgctc aattatccgg gcatcggcga gcgcgagtcg tacgtcatct accacgagga
     1021 gttggagtcg ctcgtgaaga actatcccac gatccggcgt gcgcgcttct ggatgacctt
     1081 cggtcaggag tacctgacgc acctgcgcgt gatccagaac atcggcatgg cgcgtatcga
     1141 cccgatcatc tacaacgggg tcgagatcgt cccgatccag ttcctcaagg cggttcttcc
     1201 cgatcccaag tcgctgggcg ccaactatca cggccagacc tcgatcggct gccgcatcaa
     1261 gggcctgaag gacggcaagg agcgcaccta ctatatttat aacaactgcg accacgaaca
     1321 agccttcaag gagaccggca cgcaggccgt gtcgttcacc acgggcgttc cggcggcttt
     1381 gggcgcttcg atgtgggcca agggcctctg gcgcggcgcc ggtgtgttca acgtcgagga
     1441 gttcgatccc gatccgttcc tcgccgagct gggcgagcag ggcctgccgt ggcacgagct
     1501 gttcgatgtg aatctcgaag tgtaggtttt tgaagattgc ggcgcagatg ccgcacatcc
     1561 ctcaaaatcc ccggatggat agtgccgaag tacgtcccat ccggggattt ttcacgatgc
     1621 acgacagatg caccgcaccg atcgaaaacc gcagcgggat tttccgctcc tccaaaatca
     1681 aaactgtcgt atcgttttcc gcagaaccgc ttttcccgaa atgcccctgc cggcgaccgg
     1741 ctccgatgct tatttccgga ccgggtttcg caagcgataa gtataaatgc gtattttccc
     1801 gaaaaccaag cctgcgcagc gtggttttca ggaggttttt gctacttttg caactgtttt
     1861 ggacgttttc gttgagcgag ggcagagccg ggtttgcccg gattatgccg agcggagaaa
     1921 acgaaggatg aaatccaact aaaaacaatt cgatgattga ctttctgaaa ctgccttcac
     1981 cgtgctacgt cctcgacgag gagctgctgg accggaacct ggcgactgtc gaccgtgtgc
     2041 gccgggaatc gggcgccgaa attatcgtcg ccctgaaggc ctgcgccatg tggagcattt
     2101 ttcccgagct ggcgaagcat tccgacggtg cgactgcaag ttccgccgcc gaggcgcgtc
     2161 tcgttttcga ggagttcggg cgtcccgccc acacctacgc cccggtctac acggactcca
     2221 atatcgacga aatcctcaat tgcagcgatc atatcacgtt caattcgctg tcgcagttcc
     2281 gccgcttcgg ccagaaagcc cttatcaacg gcatttcctg cggcctgcgg atcaacccgc
     2341 agtattcgcc cgtcgagacg gacctctaca acccctgcgt ccccggctcg cggctgggcg
     2401 tcacggccga acagctggcg gctcacggcg gacttccggc gggtgtcgag gggctgcatt
     2461 tccacgtcct ctgcgaatcg cgcccggagc atctgcaaaa ggcgctggag gccgtcgaga
     2521 cgcatttcgg agcgtatctc gaccggatca aatggctcaa catgggcggc ggccacctga
     2581 tgaccgcctc gtggtatgac tgcgaccgcc tgatcgccct gctgaaggcg ttcaggtccc
     2641 gccatccgaa cctgcggctg atcctcgaac ccggcagtgc cttcacgtgg cgcacgggct
     2701 ttctggtttc gaccgtcgag gacattgtgg agaacggcgg ggtgacgacg gcgatgctcg
     2761 acgtgtcgtt cgcctgccac atgcccgact gcctcgaaat gccctacaaa cccgccgtca
     2821 tcggagcgca tgaacctgcc gacggcgaaa agcgctggcg catgggcggc acgagctgcc
     2881 ttgcgggcga ctactgcggc gactgggctt tcgaccgcga gctgaaggtg ggggagcgcg
     2941 tcgtcttcga ggacatgatc cactacacga tggtcaagac cacgatgttc aacggcgtcc
     3001 accatccggc catcgtcatc gcgcgccgcg acggccgcac cgacgtcatc cgcgaattcg
     3061 gctacgagga cttccggaac cgcatgtcat agacaatatt gaattcagat atacgaaacc
     3121 tcttcatgga aaatttcaca cctaccccct acacgttgga atgtgtcgcc acgggccgcg
     3181 aattcgaaga cgccggctgg atgcttgccg acccgcagtg caaggagcct tcgctcgtgc
     3241 gcaccaaata cgcccgcaaa cagatcgacg tgaagcccgc cgactggggc ctgtaccgtt
     3301 tctcggactg gatgcccgtg cggcgtatcc tcaaaggttc gtcggctccc gtgacctata
     3361 agagcaaggg cctcgccgcg cacctcgggc tggaaaacct ctggatcacc ttcaacggct
     3421 ggtatccggc catcggggcc acgatgtcga cctgctcgtt caaggagacc gaggcctatt
     3481 cnnnnnnnnn ngtctgcggc cgcgccgctg ccgacgaacg gcgcgtgctg gtggtggctt
     3541 cggccggaaa caccgcccgg gccttcgcca aggtctgctc ggacaataac atcaggctgc
     3601 tgctctcggt tccctacgac aatatcggcg cgctgtggtt cgaccagccg ctgaacccct
     3661 gcgtgaaact catttcgtgc gagaagggcg gcgactattt cgacgccatc catttgagcg
     3721 acattgcgct gaaaagcccc ggcttctacg ccgagggcgg cgccaagaac gtcgcgcgcc
     3781 gcgacggcat ggcctgcacg gtcctttcgg ccgtgacgac catcggccgc attcccgact
     3841 actatttcca ggccgtgggc agcggcacgg gcgccattgc cgcctgggag gccaacatgc
     3901 gtctggtgga ggacggccgc ttcgggcgga atacgatgaa gctgatggtg gcgcagaacg
     3961 ccccgttcgt tccgatgtac gacgcctggc aggcggcatc gcgcaagctg ctgccttacg
     4021 acgacgacaa ggcgcgccgc gacgcggaga tcatcgacgc caaggtgctt tcgaaccgcc
     4081 gtccgcctta cagcgtcacg ggcggtcttt tcgatgcgct gaaagccacc ggcggcgagg
     4141 ttttcgtggc cacgaacgcc atggcgcgca aggcccgcaa gctgttccac gaactcgaag
     4201 gcgtcgacat ctattcggcg gcgggcgttg cgctggcgtc gctcgtcaat gccgtgaacg
     4261 cgggtaaaat cgagaaggac gccaccgtca tgctcaatgt cacgggcggc ggcgaggagc
     4321 acttcaagga gggcaaggag ctgtggtatc tcaagccgag ccacgtcttc ccgctcgaac
     4381 ccgacgaaaa cgacgtcgtg gagaaggtcg aggcgctgtt caactgaatg acagcgggtt
     4441 gactgattgc ttctgtgcga tttacacaaa cgggcctgtg tagcccgttt tttttgttac
     4501 ctttgcgcgt ccgaaccggg gatcagcagc cggacccggt tcggacgttt tttcactttt
     4561 aacccaaatt tcaaacaaat ggaaaacatc caaacaaagc agtacccctg cttcaagcgt
     4621 tggagtcgca aaaactggtc ggtttttgcc agcctccacc gttatgtgac tatcggggtc
     4681 ctctctgtcg ggatgtcgat cctgctgctt gcgacgcaag gtgcgtccgc gcagactgtc
     4741 gacacgaccg ctgtcctcaa gacattgcgg atacgggaag tcggcgtcac cgggagtcag
     4801 acggctcccg cgcgcaacgc ccagtcgcac accccgcttt tcgaccggaa agcccaggcc
     4861 ccggcgcctg tccagactct ggaagccgcc ctgcgccttg ctccttcggt cgatgtccgc
     4921 gaacgcggag gcaagggaac gcaggccgac atcttcatcc ggggaggctc tttcgaccag
     4981 accatggtcc ttctcaacgg cattgatttc accgatgccc gcaccgggca tcagtcccac
     5041 gcgctgcccg tcgacctcga ctgcatttcg gccgtcgaac tgatcgacgg cgttccgggc
     5101 gtcggagcct acgccggtgc ggtgaacatc cgcaccgcgc cgctgcggcc cacctacctg
     5161 cgtctcgaag cctcgggcgg ccagtacggc tatggctacg ggaatctttc gggcgcggtg
     5221 agtgcgggac gcttctcggt gctcggcgcg gcttcgtacc gccgcagcga cggctaccgg
     5281 cacaataccg atttctccaa ctacaacgca ttcgtacggg cgacctacga cggcgggcgg
     5341 gccgggttct tcgacttgca ggccgggtgg caggaccgcg atttcggctc caacggtttc
     5401 tatgcggcct acaatcccga ccagtgggag cataccgcca cggccctggg gtcgctgcgg
     5461 tggctgaaaa ccgcaggccg cttttcgctg ggggccgccg cgagctaccg caagaacttc
     5521 gaccgctacg actggacgcg cggcacggcg atgaaccgcc acaacacgga caatgtcgga
     5581 gcgaagctct gggccgactg cgactgggcg gcgggcgtta ccaccgtggg cggagactat
     5641 gctttcaacc acatttacag caccaatctg ggtgacaagc tttcggttcc cgaaggccat
     5701 tacacccatg ccaaggcgcg ccacacgggc aacctgtggc tgcggcacgc caagcggtgg
     5761 cggcatttcg acgcggcggc ttcggcgggc gtgagcctca cgccctacgg cacttcggcc
     5821 ctgtggagcc tttcggcggg ctatgccccc gcggccgggc tgcgcctcga agccggggcg
     5881 tggcagtcga tgcgcctgcc gaccttcacg gacctctact acacctcccc ggcgcagatc
     5941 aacaacctcg atcttacgcc ggaacacgca gtcacatacc gacttggcgt ggattacctc
     6001 aagcggagct ggaacctttc ggcgcaagcc tattaccgct ccgggcgcga catcatcgac
     6061 tgggtctggc gcgaggacat gggcagcaag tggcattccg aacagacgag cagcctcgat
     6121 accttcggga tcgaactcgc gggcggctat acggtttcgg aaggcttcct gcgccgcgtg
     6181 acgctctcgt acggctacat cacgaccgac cggaacgcgg acgtcatcgc caaaagcgcg
     6241 atggatttca tgcgtcacaa ggcggcattg gccgtggagg tgcatttcct gcggcggatg
     6301 tcgcttgcgc tgaccggctc ggtctacgac cgcaacggca gctacacgca ttaccccgaa
     6361 ccgggcaacg cctcccttaa cgaagagcgc gactacaagc cctatttcct gctcgacgga
     6421 cgtctccagt gggagaaggg catctgccgc ctttatgtcg acgccacgaa catcaccgac
     6481 acgcgctact gcgacatcgg cggaatccgc ctgccgggtt tctggtgtac gggcggggtg
     6541 acgctgacca tcggcaaata accctccgaa gtcggggcgc atccgcttgc ggagcgtttc
     6601 cggatttcgt ccggctgcaa tcctggcccg gtgcatttgt gcaccgggcc tttctgtttt
     6661 cgcaaaaagc cgcctgtttt gttacggttt tatcggaatt tttccgaata ttgtttatct
     6721 ttgaagtatt ggaatttaaa taaaacagac gatcctatgt cccaaagaat cattgaatgc
     6781 gttcccaatt tcagcgaggg gcgcgataag gccgtgatcc ggcaaatcac cgcggccatc
     6841 gaggcctccg ggggcgtcaa actgctcgac gtggaccccg gcgaggcgac caaccgcacg
     6901 gtcgtgacct tcgtcggcga acccgaagcg gtcgtcgagg ccgcttttgc cggggtgaag
     6961 cgggcggccg aactgatcga catgcgccgc cacaaggggg cgcatccccg catgggggcc
     7021 accgacgtgc tgccgctgat accgattgcg ggcgtcacgc ttgcggagtg cgccgaactg
     7081 gcgcgcgcgc tggcccggcg tatcgccgac gaactgcgca tcccgaccta ttgctacgag
     7141 gctgcggcct ttgcgcccga acggaaaaac ctcgccgtgt gccgcgccgg ggagtacgag
     7201 gccctgcccg agaaactggc gcacacggca tccgcgcccg atttcggggt gcgtcccttc
     7261 gacgaggggg ttgcccgcac gggagccacg accgtcgggg cgcgcgactt cctgatcgcc
     7321 gtgaatttca acctgaacac cacctccacg cgccgcgcca acgccatcgc cttcgacgtg
     7381 cgcgaaaagg ggcgtcccgt ccgcgagggc aaccccatca cgggcagggt ggtgaaggat
     7441 gccgcgggaa atcccgtgat gcagcccgga acgcttccgg ccacgaaggc catcggctgg
     7501 ttcatcgagg agtacggcat cgcgcaggtc tcgatgaaca tcaccgacat ctcccggacg
     7561 ccgctccgcg cggctttcga cgaggtgtgc cgcaaggccg acgcccgcgg cgtgcgcgtc
     7621 acggggaccg aaatcgtggg gctggttccg aaacgggctt tggtcgaagc cggcaaatac
     7681 ttcctccgca agcagcgtcg ctcgacgggc gtcgccgagg aggagatcgt ccgcattgcc
     7741 gtcaagtcga tgggattgga cgacctgaag ccgttcgatc ctgccgagaa ggtgatcgag
     7801 tacctgcttg aagcggaggt tccgaagaag cggcttatcg acatgacctg caaggcgttc
     7861 gccgaagaga cggcgagcga atctcccgct ccgggcggcg gctcgatcgc ggcctacatg
     7921 ggtgcgctgg gcgcggccct cgggacgatg gtcgccaacc tctcgtcgca caaggcgggg
     7981 tgggacgacc gctgggagga gttttccgac tgggccgaac gggggcaggc cgttcttgcg
     8041 gagcttctgc acctcgtgga cgaggacacg gcggcgttca accgcatcat ggcggttttc
     8101 gccatgccca agtcgaccga cgaggagagg gcggcgcgcg ccgcggcttt gcaggaggcg
     8161 acgctctatg ccacggtggt tcccctgcgg acgatgaagg ccgcctcgcg ggtttttgaa
     8221 atcgtgcgcg ccatggcctc ggagggcaac cccaattcgg tctccgacgc cggcgtgggt
     8281 gcgctggcgg cccgcagcgc ggtgctgggg gcgtgcctca atgtgaagat caacgccgcg
     8341 gggctgaaag accgtgccgt ggccgatgcg ttgatcgccg aagccgaggc gctggccgcc
     8401 gaagccgtgc gtctcgaagc ggaggtcttg cagatcgtcg aatctaaaat cggataatat
     8461 gacacgcgaa gagtttcaga acgacattcg cgcgggtatt cccgaccggc tgcccgccgc
     8521 gaaaccctat gacaaacgga tcaaccatgc gcccaaacgc aaggacatcc tttcggacga
     8581 ggagaaggcg ctggccctga aaaacgccct gcgctatttt ccggtcaggc accacgccgt
     8641 gctggcgaag gagttcgccg aggagctgcg ccgctacggc cgtatctata tgtaccgcct
     8701 gcgtcccgac tacgagatgc acgcgcgtcc gatcggcgaa tatcccgccc gctgccggca
     8761 ggcggcggcc atcatgctga tgattcagaa caacctcgac ccgcgggtcg cccagcatcc
     8821 ccacgagctg atcacctacg gcggcaacgg cgccgtgttc cagaactggg cgcagtaccg
     8881 ccttgcgatg cagtatcttt cggaaatgac tgaaaatcaa accttggtca tgtattccgg
     8941 gcatccgctg gggctgttcc cgtcgcatcc cgacgccccg cgcgtggtgg ttacgaacgg
     9001 catggtgatt cccaactact cgaaacccga cgactgggag cggctcaacg ccctcggggt
     9061 gtcgcagtac gggcagatga ccgccgggtc gtacatgtat atcgggccgc agggcatcgt
     9121 ccacggcacg acgatcacgg tgatgaacgc cgcgcgcaaa cgcttcacgg ccggccgcac
     9181 cgatacgcgc gggatgctgt tcgtctcgtc gggtctcggc ggcatgtcgg gagcgcagcc
     9241 caaggcgggc aatatttcgg gcgtggtgtc ggtcgtcgcc gagatcaacc ccaaggcggc
     9301 gcagaaacgc cacgagcagg gatgggtcga cgagctgcat gaagcgctgg atgagctgat
     9361 cccgcgtatc cgccaggctg tcaaggcgaa agaggtcgtg tcgatggcct atgtgggcaa
     9421 cgtcgtggac ctctgggagc ggctggccgc ggaggagatt ccggtcgacc tgggttcgga
     9481 ccagacctcg ctgcacaacc cctgggcggg cggttactat cccgtggggt tgagctacga
     9541 ggcgtcgaac aagatgatgg ccgaggagcc gggccgcttt agagagtgtg tgcaggagtc
     9601 gctgcggcgg caggtcgatg ccatcaacaa attgaccgac aggggaatgt atttcttcga
     9661 ctacggcaat gccttcctgc tggaagcctc gcgcgccggg gccgcggtga cgggcgaggg
     9721 cggacgcttc cgctatccct cctacgtgca ggacattatg ggacccatgt tcttcgacta
     9781 cggcttcggg ccgttccgct gggtctgcac ctcggggaag cccgaagacc tcgaaacgac
     9841 cgactctctg gccgccgaag tgctggagga gatccggaag acggctcccg acgacatccg
     9901 ggggcagctg gacgacaata tccactggat tcgcgaggcc gggcgcaacc ggctggtcgt
     9961 cgggtcgcag gcacgcattc tctatgccga ctgcgaaggg cgcgtgaaga tcgccgaggc
    10021 gttcaaccgg gccatcgccg agggccgcat cacggctccc gtggtgctgg ggcgcgacca
    10081 tcacgacgtt tcgggaaccg attcgcccta ccgcgagacc tcgaacatct acgacggttc
    10141 gtgcctgacg gccgacatgg ccgtgcagaa cgtcatcggc gatgcgttcc gcggcgcgac
    10201 gtgggtttcg atccacaacg gaggcggcgt gggctggggc gaggtgatca acggcggctt
    10261 cggcatggtg atcgacggtt cggaggatgc cggccgccgc atccgcgaaa tgctgctgtg
    10321 ggacgtcaac aacggcatcg cgcgccgcag ctgggcgcgt aacgaagggg ccgtcgaggc
    10381 catccgccgc gaaatggacc gcacgcccgg actgcgtgtg accctgcctg tttttgccga
    10441 cgagaaactt gtccgcgagg cgctgaacga acagggcggc gcttcggata aattatgaat
    10501 ttcgaattat gaattttgaa ttgtcatcca tggaacatca ccatatcacc gcggagcacc
    10561 tttcggtcgg gcgcgtccgc gaaatcctcg aacggcggct gctgctcgcg ttgagcgacg
    10621 acgcccgggc gcgcatcgtc cgctgccgcg agtacctcga ccgcaagatg gagaaccccg
    10681 agcggccgat ctacggcatc acgaccggtt tcgggtcgct gtgcgacatt tcggtgggcc
    10741 gcgacgagct gtcgcgcctg caacagaacc tcgtgatgtc gcacgcctgc ggaaccgggg
    10801 agcgcgtgcc ctcggagatc gtgcggctga ttctgctgct caagatacag tcgctcgcct
    10861 acggccattc gggcgtgcag ctggcgacgg tggagcgtct cgtggagttt ttcaaccgcg
    10921 gcatcctgcc cgtcgtctat cagcagggtt cgctgggtgc ttcgggcgac ctcgcgccgc
    10981 tggcacatat gagcctgccg ctgctggggc tgggcgaggt ggagtataag ggcgaggtgc
    11041 gtccctcggc cgaagtgctt gccgaactgg ggctggagcc gatccggttg cagtcgaaag
    11101 agggccttgc gctgctgaac ggcacgcagt ttatgagcgc ctacggcgtc tggtcgctga
    11161 tccacgcccg gcggctgagc gagtgggccg accgcatcgg ggcgttgtcg ttagacgcct
    11221 tcgacggtcg tatcgagcct ttctgcgacg aggtgcacct gatccgcgcc caccgggggc
    11281 agctcgccac ggcccggaat gtccgcgggc tgctcgaagg cagcgaactg atcgcccgcc
    11341 ccaagcacca cgtgcaggac ccctattcgt tccgctgcat gccgcaggtt cacggagcct
    11401 cgaaggacac gatcgactat gtggagagcg tgctgaccac ggaaatcaac tccacgacgg
    11461 acaatccgac ggtcttcccc gagggagaca tggtcgtctc ggcgggcaat ttccacggac
    11521 agccgatcgc tctggcgatg gatttcctgg cgatcgccct ggccgagctg ggcaacatct
    11581 ccgagcgtcg cacctacaaa ctgatctccg gggcgcgcga actgcccaaa ttcctcgtgg
    11641 cgaatcccgg gctgaacagc ggctttatga ttccgcagta taccgcggcg tcgatcgtga
    11701 gccagtccaa ggggctgtgc atgcccgcgt cggtcgattc gatcccctcg tcgcaggggc
    11761 aggaggacca tgtgagcatg ggttccaacg ctgccacgaa gctctggcgc gtggtctgca
    11821 acaccgaacg ggtgctggcc atcgagctgt tcaacgccgc gcaggccatc gagttccgcc
    11881 gtccggcgca cacgtcgccc gagttggagc gaatgctggc cgactatcgc aaagaggttc
    11941 ccttcatcga caacgacgag gtgatgtatc cccatatcga agcctccgtc cgattcctcc
    12001 gcggcctatg agactgctgg tgaagaacat cgcccgcatc gtcggcatcg aatcgacggg
    12061 ccgtctgcgc tgctgcggtg ccgacatgaa caagctgggc atgctcgacg acgcgtggct
    12121 gctggctgaa gacggccgtt tcgcggcgtt cggacgcatg gactctctgg gcgacatcgc
    12181 cgccgacgag gtcgtcgacg cggcaggggg catgctcttt ccgtcgttct gcgactcgca
    12241 cacccacctg gtctacgccg ggagccgtga gcgggagttt ctggacaaga tcaacggttt
    12301 gtcgtacgag gagatcgccc ggcggggcgg gggcattctc aactctgccg accggctgca
    12361 cgagacttcg gaggacgaac tctatgcgca ggcgatggag cgcgtgcgcg agatcgcggc
    12421 gatgggtacg gggtgcgtgg agatcaagag cggctacggc ctttcgaccg gggacgagct
    12481 gaagatgctg cgcgtcatcc gccgcatccg cgaaagcgtg ccgctggagg tgcgggccac
    12541 gttcctcggg gcgcatgccg tggcgcgtgc ctaccgggga cggcaggggg agtatgtcga
    12601 tctggtgtgc aacgaaatgc tgcccgccgt ggcggccgaa gggctggccg atttcgtcga
    12661 cgtcttctgc gacgaaggtt ttttcacggt cgaagagacg gcccgtattc tcaaggccgc
    12721 gcgcaaactg gggctgcggg cgaaaatcca tgccaacgaa ctggccgtct cgggcggcgt
    12781 gcaggtgggc gtggcctgcg acgccctgtc ggtggaccac ctcgaacgca tgggacggga
    12841 ggagatcgaa gcgttgcgcg gcgcggcgac catgccgacg ctgctgccgg gcgcggcgtt
    12901 cttcctcggg atgagctatc ctccggcgcg cgcgatgatc gacgccgggc tgggcgtggc
    12961 gctggcttcg gactacaacc ccgggtcgtc gccctcgggc aacatgcgca tggtctgttc
    13021 gctggcctcg atccgcatga agatgacccc cgccgaggcg atcaacgccg cgacgctcaa
    13081 cggcgcctat gc
//
