LOCUS       c00035_gnlPro..        14906 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IIKKHECN_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 00:58:50
            Original ID  :: gnl|Prokka|IIKKHECN_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14906
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14906
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1278:4906]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1279..4906
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..14906
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14906
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             106..1020
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MKKIISLLVLVLSMGIYTGCGKENTEIENSRMEEQTTPENSENDE
                     IHLEDELNIDFTCDYSESIKEDVDDVVAASTSLQEELTNMEKVTQKYTPLAEAAQTQGE
                     MNVAAHWLYTIWDTELNNLWSRLSSSADRQTKEKLLAEQRNWIDLKEEVTLLNIGSREE
                     NGSMYPLLQDSYLEEITKNRAYVLARELAKIKGEDFAMPEVSAKYGTFVDNQGTGDIYS
                     SLITRQNWEGTDEAVISIYRQGEMEGSFVDHGNGELSFTSEDGSVKGMIKIDGWNGASF
                     KVTETYGESPFSAGEEFEFPFAV"
     CDS             complement(1279..3756)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_2"
                     /sec_met_domain="PFOR_II (E-value: 1.9e-22, bitscore: 70.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1e-55, bitscore: 179.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.3e-12, bitscore:
                     37.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKIMYDSGNELAAFAAKQINYHVMGYYPITPSTQIAENLDVM
                     GAEGLHDIALIAAEGEHSAAGICYGASAAGGRVFNATSANGLLYALEQFPVQSGTRMPM
                     VMNVACRTVSGPLCIKGDHSDVMYLLNTGWIILFADEPQKVYDFNLLGLKLAEAVRLPV
                     AVAFDGFFTSHQKRKCLVFENDDTVTRYIGEKLSCDNPKVSAFAGTGTCGAAGELPYAS
                     VLDLAHPVSIGSYMNEPDVINNRYQLHLAMEAARNKLPKLFTEYAALSGRELSFCGAYR
                     HEDAEVLLFVLGSSYHTAMEAVDRLRQDGIAAGVITLYVLRPFPAKELRVLCHNASTIL
                     AADRQDSYGAGGGNMSLELKAALSSLPHPPRILSRIYGLGGKDFFVEDALALFKEALSP
                     DAPAFDYYGVTAGTDAPDAADSAGTSFSGTDAVTAVSHPAASINEDMISSASGRADRTI
                     ADQASGTSGKADQSMAAPAMQPQYFKPVTKEESSPGLTTCTFDPATGKMKVSGGSVKDT
                     TAMPMRVAPGHGACPGCGIPINVNLLLKGIEGNVVLLFQTGCGMVVTTGYPKTAFRVPF
                     LHNLFQNGAATLSGVVEAFHQRQKRGEYPDGEITFVMVSGDGGMDIGMGSALGTALRGH
                     KLIIFEYDNGGYMNTGYQLSYSTPLGAKSSTSHVGKTQYGKNFFHKDTPELMAATHIPY
                     VATVAESNPADFIRKAAKAAAYSREFGTAYIKALSACPLNWNDKPNLERSVIAAAVDCC
                     YFPLYEIEHGITVLNYDPASSNKKIPVTEWLGMMGRTRHLLKEEYRSVTEEIQKEIDRR
                     YARLKARAEHPLL"
     CDS             complement(3815..4906)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="POR (E-value: 3.3e-25, bitscore: 79.8,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_7 (E-value: 1.3e-09, bitscore: 29.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.3e-09, bitscore: 27.6,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00011, bitscore: 13.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNTLSLPVTNENGSYEIRLESIGGLGANLCGKMLGELGALSLSL
                     NSLSFSSYGSEKRGSPVKAYVRWCADDRPLRVNSPVTRPHLLGIFHGGLIGTYPVLEGV
                     TVDTKIVLNTPLSADEAADKYHISIGELYCLDALVLAMESHSRINMVMLGALVRASGFI
                     PPEAAETLCRDTIGKKYPALIEANLAGLRLGYENVKMAQGDRNLAPLPDAPADRYAWGY
                     ANAPIGGVNPRIGSTVSNDLTASREGYIPLFIQEKCINCGLCDTACPDMVFQFAPGTYR
                     GKNCMVNRGLDYYHCKGCLRCVEVCPTNALVPALEKDYPEKPHFLPNQHLLPDAIRYQT
                     VGANSWITSDSFTDEKRVDGGVV"
     CDS             5086..6225
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MMDNMLQKITDFIKKETVLTIATAFAVASAFWVHPGPQYVGYIDW
                     RVLGILLSLMLIVAGFQSNGLFDAIGSRLLAKTKNTAQLMLVLVFLCFFSSMFITNDVA
                     LLTFVPFACTILQKCHQERLIVTTFVLQTLAANLGSMLTPVGNPQNLYLYSISGAGLGE
                     FIGWMAPYTLVSGVLLLLVVFVLSAGKRRISLETGALLQTSGAAGRKKNGIYLALFVLS
                     LLSVARVLPWELMLAVVLIVLIFTDRAVFLQVDYCLLFTFISFFIFIGNMGNIEAVRSV
                     LQSLVAGRELAVGIGASQIISNVPATLLLADFTHNLKNLTIGVNLGGLGTLIASMASLI
                     SYKIYAHNYNKTKGRYLLWFTIANVLFLAVLVLVYVFIS"
     CDS             6269..7186
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="MENTTEERMENTTETRMGGMDMSDKKMNAESLRGTVCVLLSAVCF
                     STGGVLIKSIPWSSVTIQGARSIFSVLVVGCYMLLRRQKFVWNKTVLFGAVCNTVMAFA
                     FVAATKLTTAANAIVLQFTEPVFVILLMWLIFHKKPGRDAVFACAGVFAGILCFFYTSL
                     DAGVMAGNLLAILSGLAYALVMMQKKFRGADFESSLLVSCALSAAIGIPFYGQESEMSL
                     HIWFFVLLLGVVQFGLSYVFLSRGLDAVSPVTASLTSTIEPILNPVLVAVFYGETIGAT
                     AVIGALLVVGSATVYNVRQAKKAA"
     CDS             7635..9059
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="EutA (E-value: 4.7e-177, bitscore: 580.1,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTEEILSAGIDIGTSTTQLVFSRMILQNTGGFGRIPQIKVVSKE
                     VIYESEIYFTPLSSREEIDGERVHEIIKKEYEKAGVCPADLATGAVIITGETSRKRNAE
                     SVVRAIADVAGEFVVATAGADLESVLAGKGAGAADLSQKTGKRVVNLDIGGGTTNICVF
                     EDGNMVDTACLDIGGRLIRVKDGRVIYMAPKLQWLCGRLEIDLAEGGTAEPEKLRRLTA
                     AMAELLAEAVHLAPEAAELSYMQTNHLLADGTPSDIVMFSGGVAACFGEEEDLFRYGDI
                     GILLAQAIRKNEAFRRAAVTDARETMRATVIGAGNYSMNISGSTIEYTTKPFPLKNIPV
                     VKLPLEREEEIEKLPENMHRALLLYREDQEKDRQVALAMKGLKCPTFAQVQRIAELIAD
                     QYVRECGMDRHLILVLEEDIGKAIGQALHHRLKEKCSVICIDGISCGSGDFIDLGEPVA
                     SGNVIPVIVKTLIFNG"
     CDS             9069..10436
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_7"
                     /sec_met_domain="EutB (E-value: 4e-202, bitscore: 662.3,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILKTRMLGQTYEFKDVKDVLAKASEKKSGDELAGVGAESALERI
                     AAKEVLAQLTVADLTEHPVVPYEEDAVTRIIQDDIDETVYGTIRDRTIQEMREWILCDA
                     TDSGALMRASRGMTSEVIAGISKIMSNMDLILAGSKIRVTATCNTTIGTENVLASRLQP
                     NHPVDDVEGVAASTLEGLSYGIGDAVIGLNPAIDTVDSTLAIWKVLGDIRDKYEIPTQT
                     CVLSHVTTQMEALRTGQGSADLCFQSIAGSEAALSAFGINTGMLSEAEMLFREEGPAKG
                     PNVMYFETGQGSELSSSAAFGSDQQTMECRCYGLARHYHPFLVNTVVGFMGPEYIYDTK
                     QLTRAALEDVFCGHLHGLPMGCDVCYTNHMPTDQNDSETILTLLGTAGVHYVMGLPQAD
                     DIMLMYQSTSYHDVASIRQLLKKEPIPEFKAWLEKRGIWENGHLGPNAGDPSIFFK"
     CDS             10451..11236
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) EutC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_8"
                     /sec_met_domain="EutC (E-value: 4.7e-77, bitscore: 249.0,
                     seeds: 176, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKETACLRDITETDIMEYMQVEHPHNEKELWKMKHATPARIGI
                     GRCGARYTTEAQLRFLAAHAAANDAVFNEVPKEVVKELGVFEVRTRCSNKNEMLLRPDW
                     GREFLPDARQKIAENCIHHPQVQIYFGDGLCSPSIKANIPDLFPTIKMGLEDKGITVGT
                     PFFVRYCRVNTARTIGPLLDAEVTCVLIGERPGLLTSESMSAYIAYHARPDMLESEYTV
                     VSNISRHGVPPVEAAAHIADLIAQILEKKKSGVEFSKAE"
     CDS             11320..12801
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_9"
                     /sec_met_domain="AA_permease_2 (E-value: 4e-46, bitscore:
                     148.2, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNEGGQLVRALGLKESISMTIGTVVGVGLFTCGSSQIGYVGSG
                     IIVITFLSLLISIWPCLIYGEMSAALPCAGGTYNYAKRGLNRVWANLAGWHYIISVVGI
                     GAGETLAFSNYFKILFGELGINIEGVDSRIIAIVLVLFFLILNFRGIEMSGKAQTGFIF
                     FFWGCAVAWFLYMIPHIHLDYFGGIAMDSLPPFKEMMYIFGLVWWCYTGFETCVSMGAE
                     TKYPQYTLPRALKVSVFLVFAVNALFQWFLVGLVPHEFYHILAVADAPYAEGLRAAGLV
                     GFPIILLCIGIAFGGDLSTINPGIAAPARYIYTMAEDGSLPKFLCKVHPKYKTPYMAVL
                     VVGIINIILIATGSINYIASVSLISLAVCYMIGCLAYLGLKKHYPDMNRPYRAPAGTVG
                     CYVTIAAYTIILIFADRIALLTAAVVTVAAIVYWALFTRKHENKIPSIEEEIGILEEPS
                     PQEKAKMDKEYRIWKAGTILVTVIALGIYIIPVLF"
     CDS             12830..14392
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_10"
                     /sec_met_domain="Amidohydro_3 (E-value: 3.6e-55, bitscore:
                     178.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLYEGNILTCDKENRIAHYLLEDQGKILYCGDELPAGCVAAERV
                     STGEGALIPPFVDSHIHFASYATFHAGLNVMNARSNEEILQMLREHVKKTKEKLVIGFG
                     ASPYSVSDGHLVRRVQLDEVCPDKPLFLVKYDGHACVVNTVLLNEVRGKVQHLRGFHED
                     TGEMNQEAFFAVSDYITASLSTVQLVAHMQKALDDLAARGIGMIHTVSGVGFARDLDVD
                     LERFFARGITNGMQMRVFMQTLDVNKAVKRKLPRIGGCFETALDGCFGSMDAALLSPYE
                     NTSDCGVLYYSDEKVTEFCKAANRAGLQIEMHAIGDKAFVQAVRAIKAALDDLPREDHR
                     HTIIHACLPTAEEIAVCERYHINLAVQTAFIDWPQEPDSYLEQILGERAGRLNPIRTFC
                     EHGLILSAGSDGPCTDPDPLLWMYKACNHSNPAESISVQQALRMCTYNGYYTTFDERER
                     XXXXAGKIADMVLLDRNPYDIPKEELASVKVKQLYLRGQEYKKGNGGGAAQILRGMIKR
                     GKC"
ORIGIN
        1 aatccgtggg acagagaata ccggaaaaag aaatcgctaa cttcaagttt gtagagcgaa
       61 tggaaacaca ggatgaagaa aagaaaatat ggggagaggt aatatatgaa aaaaataatc
      121 tctctgctgg tactggtgtt aagcatggga atttataccg gatgtggtaa agagaataca
      181 gaaatcgaaa attcccgcat ggaagaacaa actacacctg agaacagtga aaacgatgag
      241 attcatttgg aggatgaact gaatatagat tttacttgcg attattctga gagtattaag
      301 gaagatgtag acgatgtagt agcggcttcc acatctctgc aggaagagtt gacgaatatg
      361 gagaaggtca cacaaaagta tacgccatta gctgaggcgg cacaaacgca gggcgaaatg
      421 aatgtagccg ctcattggct ctatacgata tgggatacgg aactgaataa tctctggagc
      481 agattgagta gttcagcgga ccggcagacg aaggagaagc ttctggcaga gcagagaaac
      541 tggatagatc tgaaagaaga agtgacttta ttaaatattg gttccagaga agaaaacggt
      601 agtatgtatc cgcttttaca ggactcttat ctggaggaaa ttacaaaaaa cagggcgtat
      661 gttcttgcaa gagagctggc gaagataaaa ggggaagact ttgctatgcc ggaagtttcc
      721 gcaaagtacg gaacctttgt agataatcag ggaaccggtg atatatacag ttctctgatc
      781 accagacaga attgggaagg aacagatgaa gcggtgatct ctatttacag acagggggaa
      841 atggaaggaa gctttgtgga tcatggaaat ggagaactga gctttacatc agaagacgga
      901 agtgtaaaag gaatgatcaa aatcgacgga tggaatggcg caagttttaa agttacggaa
      961 acatacggag aatctccgtt ttctgcagga gaagaatttg aatttccttt tgccgtttga
     1021 tttgtgatga tctgtgtctt ttcaggcttt gagcactccg cgggtgtgcc cgcggagtgt
     1081 caaagcgtgg caagagacac ggaatggagt ggaaagggcg gcaggaagaa attcctgccg
     1141 ctttttcaat taccggtctg gctatgagca tccggacaca gcatcccgcc ggccggatgc
     1201 tctctgtgcg cttacagaag cggatgctcg gcgcgcgctt taagccggtc gtagcgccgg
     1261 tagatctcct ctgtgcgcct acagaagcgg atgctcggcg cgcgccttaa gacgggcgta
     1321 gcggcggtca atctccttct ggatctcctc ggtcacggag cggtactcct ccttcagcag
     1381 atgcctggtg cgtcccatca tacccagcca ttctgtgaca gggattttct tattgctcga
     1441 agcaggatca taattcagca ctgtgatgcc atgttcgatt tcgtagagcg gaaaataaca
     1501 gcagtctacg gcggcagcaa tgacgctccg ctccagattg ggcttatcat tccagtttaa
     1561 cggacaggcg gacagcgcct tgatataggc agtgccaaac tctctggaat aggcggcggc
     1621 ttttgccgct ttccggataa aatcggccgg atttgattct gcgaccgtgg cgacataggg
     1681 aatgtgggtt gcggccatca gctccggtgt gtccttgtgg aagaagttct tgccgtactg
     1741 cgtctttccg acatgggaag tagaactctt tgcgccgagc ggtgtggagt aggagagctg
     1801 gtagccggta ttcatgtagc cgccgttatc gtactcaaaa atgatcagct tatgaccgcg
     1861 cagggcggtg ccgagtgccg atcccatacc gatatccatg ccgccgtcac cgctcaccat
     1921 cacaaaggta atctcgccgt ccggatattc cccgcgcttc tggcgctggt gaaacgcctc
     1981 cacaacgccg cttagggtcg ccgcgccgtt ctgaaacaga ttgtgcagaa atggaacgcg
     2041 gaacgcggtt ttggggtagc cggttgtcac taccatgccg cagccggtct gaaacagcag
     2101 gacgacattt ccctcgatgc cctttaacag gaggtttaca ttgatcggaa tgccgcagcc
     2161 cgggcaggca ccgtgtcccg gtgcgacgcg catcggcatg gcggtcgtat cttttacgga
     2221 gccgccggag actttcattt tcccggttgc gggatcaaag gtgcaggtgg tgagacccgg
     2281 cgaggattct tcctttgtga caggcttaaa atactgcggc tgcatcgccg gagctgccat
     2341 cgactggtca gccttgccgg aagtgcccga agcctggtcc gctattgtgc ggtcagccct
     2401 gccggaggca cttgaaatca tatcttcgtt gatagaggct gccgggtgtg aaaccgccgt
     2461 caccgcgtct gtcccggaga aagatgtccc tgcggaatct gccgcatccg gtgcatccgt
     2521 gccggcagtg acgccgtagt aatcgaacgc cggagcgtcc ggcgagagtg cctctttaaa
     2581 gagggcgagg gcgtcctcca cgaaaaagtc cttgccgccg agaccgtaga tccggcttaa
     2641 aatgcgcggc gggtgcggca gggaagagag agcggccttt aattcaagcg acatgttgcc
     2701 gcccccggcg ccgtagctgt cctgccggtc tgctgccaga atcgtggaag cattgtggca
     2761 gagcacccga agttccttag cggggaacgg gcgcagaacg tagagggtga tcacgcctgc
     2821 cgctatgccg tcctgccgca gccggtcgac ggcttccatg gcggtatggt aggaggaacc
     2881 gagcacgaaa agcagaacct cggcgtcctc gtgccggtag gcaccgcaga aggaaagttc
     2941 cctgccggag agggcggcat attctgtaaa cagcttcggc agcttgtttc tcgcggcttc
     3001 catggcgaga tggagctggt agcggttatt gatgacatcc ggctcgttca tataggaacc
     3061 gatggaaacc ggatgcgcga gatctaagac gctggcgtaa ggaagctccc cggcggcgcc
     3121 gcaggtgccg gtgccggcaa atgcggagac cttcgggttg tcacaggaaa gcttttcccc
     3181 gatatagcgg gtgacggtgt catcattctc aaatacaagg cacttgcgct tctgatggct
     3241 cgtaaaaaag ccgtcgaacg cgactgcgac cgggagacgg acagcctcgg caagctttag
     3301 accgagcagg ttaaaatcat agactttctg cggttcatcg gcaaaaagaa tgatccagcc
     3361 tgtgttgagc agatacatga cgtcgctgtg atcgcctttg atgcacaaag ggccggaaac
     3421 cgtgcggcat gcaacattca tgaccatcgg catgcgtgtg ccggactgca ccggaaactg
     3481 ttctaaggcg tacaaaagcc cgttggcgct ggtggcatta aatacacggc ctccagcggc
     3541 tgaggcgccg tagcagatgc cggcggcgct gtgttctccc tcggcggcga tcagggcaat
     3601 gtcgtgaagc ccctccgcgc ccatgacatc cagattttcc gcaatctgtg tagagggcgt
     3661 gatcggataa taccccatga cgtgatagtt gatctgcttt gcggcaaatg cagcaagctc
     3721 attgccgctg tcatacataa ttttttgttt ttccatatca ttctccattc tgcagacgct
     3781 gtgcgccggt acgattcacg ggtgctgcct gcatttatac gacgcctccg tcgacccgct
     3841 tttcgtcggt aaaagaatcg cttgtgatcc aggaattcgc accgacggtc tgatagcgga
     3901 tggcgtcggg cagcagatgc tgattcggaa gaaaatgcgg tttttccggg taatcttttt
     3961 cgagtgccgg cacgagtgca ttggtggggc agacttccac acagcgcagg cagcccttgc
     4021 agtgatagta gtcaagcccc cggttgacca tgcagttttt tccgcggtag gtgccgggag
     4081 caaactggaa gaccatatcc gggcatgccg tgtcacacag tccgcagttg atacattttt
     4141 cctgaataaa aaggggaatg tacccttcgc gcgaggcggt cagatcgttg gagacggtgc
     4201 ttccgatccg cggattgacg ccgccgatcg gagcgttggc atagccccaa gcataccggt
     4261 ccgccggggc gtccggcaga ggggcgaggt tgcggtcgcc ctgagccatt ttgacatttt
     4321 catatcccag gcgcagaccc gcgagattgg cttcgatgag tgcgggatat tttttcccga
     4381 tcgtatcgcg gcagagcgtt tcggcagctt ccggcgggat aaatccgctg gcgcgcacca
     4441 gagcaccgag catgaccatg ttgatgcggg aatgactttc catcgcaagt acgagcgcat
     4501 ccagacaata gagttctccg atggaaatat ggtatttatc tgccgcctcg tcagcggaca
     4561 agggggtatt taatacgatt ttggtgtcta cggtgacgcc ctccaagacc gggtaggtgc
     4621 cgatcagtcc cccgtgaaag atgccaagca gatgcggccg ggtcacgggg ctgttgacgc
     4681 gcagcgggcg gtcatcggcg caccagcgga catacgcctt gaccggtgaa ccgcgctttt
     4741 cggagccgta gctggaaaag cttaaggaat tgagcgaaag cgacagtgcg ccgagctccc
     4801 cgagcatttt tccgcagaga ttggcgccca gcccgccgat gctctccagg cggatctcat
     4861 aggagccgtt ttcatttgtg acaggtaagg ataatgtatt tttcacgtaa atctccattc
     4921 ctgcgcgggc agctgtgcat gggaaaatga caggcaccgg ctgtgcgcat acagcgataa
     4981 caggctatct tgtggtagta tgccgcattt tcagaaaaaa atcctatgca agtgcaaaaa
     5041 agagaagtaa aataggaaag gaatttttac aatgaaacag aaaagatgat ggacaacatg
     5101 ttgcagaaga tcacagattt tataaaaaaa gaaacggtac tcacgatcgc cacagccttc
     5161 gctgtggcat cggcattctg ggtgcacccg ggtccgcagt acgtgggcta cattgactgg
     5221 cgcgtgctcg gcattttgct gtcgctgatg ctgattgtgg caggatttca gagcaacgga
     5281 ctgttcgatg cgatcggcag ccggcttctg gcaaagacca aaaataccgc gcagctgatg
     5341 ctggtgcttg tttttttgtg ctttttttcc agtatgttta tcacaaacga cgtcgcactt
     5401 ctgacgtttg tgccgtttgc gtgcacgatc ctgcagaaat gccaccagga gcggctgatt
     5461 gtgacaacgt ttgtgctgca gacgcttgca gcgaatctgg ggagcatgct gacgccggtc
     5521 gggaatccgc agaatctgta tctttacagc atctccggtg ccgggctggg tgaatttatc
     5581 ggatggatgg cgccgtatac gctcgtgtca ggtgtgcttc tgctgcttgt cgtgttcgtg
     5641 ctcagtgcgg gcaagcgccg gatctcgctg gagacggggg cacttttgca gacgtccgga
     5701 gcagccggca ggaagaaaaa cgggatttat ctggcgctct ttgtgctaag tctgctttcg
     5761 gtagcgcggg tgcttccgtg ggagctaatg ctcgccgtgg tgctcattgt actcattttt
     5821 acggatcgcg cggtgttttt gcaggtggat tactgtctgc tgtttacgtt tatcagtttc
     5881 ttcatcttca tcggcaatat ggggaatatc gaggcggtac ggtctgtcct gcaaagtctt
     5941 gtggcgggca gggaactggc ggtcggcatc ggtgcgagcc agatcatcag caatgttccc
     6001 gcgaccctgc ttctggcaga ttttacgcac aatctgaaaa atcttacgat cggcgtgaat
     6061 ctgggcggac tgggaacgct catcgcttcg atggcgagcc tgatctctta taagatctac
     6121 gcgcacaatt ataataagac caaggggcgg tatctcctgt ggtttacgat cgcaaacgta
     6181 ctgtttctgg cagtactcgt gctggtctat gtttttatct cataggaagt ggcagtagca
     6241 cagatgggag aatccggcag aagagcggat ggagaatacg acagaagagc ggatggagaa
     6301 tacgacagaa acccggatgg gaggaatgga tatgagtgat aaaaaaatga atgcggaaag
     6361 tctgcgggga acggtttgcg tactgttatc ggcagtctgt ttcagcaccg gaggcgtttt
     6421 aatcaagtcg attccgtggt cgtcggtgac gatccaggga gcgcgcagta ttttctcggt
     6481 gctggttgtg ggatgttaca tgcttctgcg ccgccagaag tttgtgtgga ataagacggt
     6541 gctcttcggt gcggtgtgca atacggtgat ggcgtttgcc tttgtggcgg cgaccaagct
     6601 cacgacggct gccaatgcga tcgtgctgca gttcacagag ccggtgtttg tcattctcct
     6661 gatgtggctg atctttcaca aaaagccggg gcgggacgcg gtgtttgcct gcgcgggagt
     6721 ctttgccggg attctctgct tcttttatac gtcgctggat gccggagtca tggcggggaa
     6781 tctgcttgcg attctctcag gacttgccta tgcgcttgtg atgatgcaga agaaattccg
     6841 cggagcggac tttgaatcat cacttctggt gtcctgcgcg ctgagcgcgg cgatcggaat
     6901 cccgttttac gggcaggaga gcgagatgtc gctgcatatc tggttcttcg tgctgctgct
     6961 cggcgtggtg cagttcggac tgtcctatgt gtttttgtcg cggggactgg acgcagtctc
     7021 tccggtcacg gcgtcgctga cctcgacgat cgagccgatc ttaaatccgg ttctggtggc
     7081 tgttttttat ggggagacaa tcggcgcaac ggctgtcatt ggcgccctgc tggtggtcgg
     7141 ttcggcgacg gtctataatg taaggcaggc aaaaaaagcc gcctaagtac ctacaaaaag
     7201 gcgggaagaa gccacacaaa aggtacaaaa aagacaaaaa tatatgagca gccggtaaaa
     7261 tatttgttaa aaaaggaatt gctgaataaa aagtgtcatg ctataataac ttttaaattc
     7321 agatatcaga tgacatgtgc aagggagcac cgcggtagcg gctgctctct ttttttttgt
     7381 aattaggaaa cttcgttcct attacataaa aaagctcccc ggggatgcgc actgcggcgg
     7441 agacgaaaga tgtcgcaaga gcgacccgcc gcaggcggag aatcctgcag gcagggttct
     7501 tatttattcc ataggaaata ccagattgca ctaagatgta aaagccgggc tgccgcagat
     7561 aaaaaaccac cgcgcaatta tatggtgagc ggcagacgca gacaaaaaag aacagttttt
     7621 ggaggaggag aagaatgcag acggaagaga ttttaagtgc cggaattgat attggaacgt
     7681 cgacgacgca gcttgtgttc agcaggatga ttctccagaa cacaggcgga tttggcagaa
     7741 ttccacagat caaggtagtg tccaaggagg tcatttacga gagtgagatt tattttacac
     7801 cgctgtcatc ccgggaggag attgatgggg agcgcgtgca tgagattata aaaaaggagt
     7861 atgagaaggc gggcgtttgt ccggcagatc ttgcaaccgg agccgtcatc atcacggggg
     7921 agacttcccg gaaaagaaat gccgagtcgg tagtacgggc gattgccgac gtggcgggag
     7981 agtttgtcgt ggcgacagcg ggagcggatc tggagtctgt tttggcagga aaaggtgcgg
     8041 gagccgcaga tttgtcccaa aagacgggga agcgggtagt caatctggat atcggcggcg
     8101 gcacgacaaa tatctgtgtc tttgaggacg gaaatatggt tgatacggca tgcctcgaca
     8161 tcggcggcag actgatccgc gtgaaggacg gcagagtgat ctacatggcg ccaaagctgc
     8221 aatggctgtg cggcaggctt gagattgatc ttgcggaggg cgggacggca gaaccggaaa
     8281 agctgcgcag actcaccgct gcgatggcgg aacttcttgc ggaggcagtg catctggcgc
     8341 cagaggcagc agagctttcc tacatgcaga ccaaccatct tctggcggat ggcacgccgt
     8401 ccgatattgt gatgttctcc ggtggggtgg cggcatgctt cggggaagag gaggatctgt
     8461 tccgctatgg ggacatcgga atccttttgg cgcaggcgat ccggaagaac gaagcgtttc
     8521 gccgggcggc agtgacggat gcgcgggaaa ccatgcgggc gacggtgatc ggcgcaggaa
     8581 actacagcat gaacatttcc ggaagtacga ttgagtacac gacgaaaccg tttccgttaa
     8641 aaaatattcc ggtggtgaag cttccactgg agcgtgagga agagattgaa aaactgccgg
     8701 aaaacatgca ccgggcgctt ctgctttacc gggaggatca ggaaaaagac cggcaggtgg
     8761 cgcttgccat gaaggggtta aagtgcccta ctttcgcaca ggtacaaaga atagcagaac
     8821 tgattgcaga ccagtatgtc agggagtgcg gcatggacag gcatctgatc ctggtgcttg
     8881 aggaggatat cggaaaagca atcgggcagg cgctgcatca cagactgaaa gagaagtgca
     8941 gcgttatctg catcgatgga atcagctgcg ggagcggaga ttttattgat ctgggcgaac
     9001 cggttgcatc gggtaacgtc attcccgtga tagtaaagac attgatattt aatggttagg
     9061 agcagcttat gatattaaag acacggatgc tggggcagac ctatgaattt aaggatgtaa
     9121 aagatgtgct ggcaaaggcg agcgagaaaa aatcgggaga cgagctggca ggcgtcgggg
     9181 cggagagcgc cttagagcgg attgccgcca aggaggtgct ggcgcagctg accgtggcag
     9241 atttaacaga gcatcctgta gtgccctacg aggaggatgc ggtgacgcgg atcattcagg
     9301 atgatatcga tgaaacggtc tacggcacga tcagggacag aacgatccag gagatgcggg
     9361 agtggattct ctgtgacgcc acagacagcg gggcgctgat gcgcgcaagc cggggaatga
     9421 ccagcgaagt gattgccggg atttccaaga ttatgagcaa tatggatctg attcttgccg
     9481 gaagcaagat ccgggtgacg gcgacctgca ataccacgat cggcacggaa aacgtgcttg
     9541 cgtcgagact gcagcccaat catccggtag atgatgtgga aggcgtggca gccagcacct
     9601 tagagggact cagctacggc atcggtgacg ccgtcatcgg actgaatccg gcaattgata
     9661 cggtggacag cacacttgcg atctggaaag tgctcgggga catccgggat aaatatgaga
     9721 ttccgacaca gacctgtgtg ctctcacatg tgacaacaca gatggaagcg cttagaaccg
     9781 ggcagggaag cgccgattta tgtttccagt cgattgcggg atcggaggcg gcgctctcgg
     9841 cgtttggcat caataccggg atgctgtcgg aggcggagat gctgtttcgg gaggagggac
     9901 cggcaaaggg tcccaacgtc atgtattttg agaccgggca gggttcggaa ctgtcatcct
     9961 cggcggcgtt tggcagcgat cagcagacga tggaatgcag atgttacggt ctggcacggc
    10021 actatcaccc gtttctggtg aacacggtgg taggtttcat gggaccggag tatatctacg
    10081 acaccaagca gctcacgagg gcggcgctcg aggacgtctt ctgtgggcat ctgcacggac
    10141 tgccgatggg atgcgacgta tgttatacga accacatgcc gaccgatcag aacgactcgg
    10201 agacgatcct gacacttctg ggaacggcgg gcgttcacta tgtgatggga ctgccgcagg
    10261 cggatgatat tatgctgatg tatcagtcca ccagctatca cgatgtggcg agtatccggc
    10321 agctgctgaa aaaggagccg ataccggagt ttaaagcatg gcttgaaaaa cggggcatct
    10381 gggaaaacgg gcatctcggt ccgaacgccg gagacccgtc catattcttt aaataggagg
    10441 aacgggattt atgagtgaaa aagagaccgc ctgcctccgc gatattacag agacagacat
    10501 tatggaatat atgcaggtgg agcacccgca caatgaaaag gagctttgga agatgaagca
    10561 tgcgacgccc gcgcggatcg ggatcggacg gtgcggcgca cgctatacga ccgaggcaca
    10621 gctccggttt ctggcggcgc atgcggcggc aaacgacgcg gtgttcaatg aagtgccaaa
    10681 ggaagtggta aaggaacttg gcgtttttga ggtgcggaca agatgttcca ataaaaacga
    10741 aatgcttctc cgcccggact ggggcaggga gtttttgccg gatgccagac aaaaaattgc
    10801 ggaaaactgc attcaccatc cgcaggttca gatttatttt ggcgacggtc tgtgctcgcc
    10861 gtccatcaag gcgaacatac cggatctgtt tccaaccata aaaatgggtc tggaggataa
    10921 gggaattacc gtcgggacgc cgtttttcgt gcgttattgc agagtgaata ccgcgcggac
    10981 gatcggaccg ctcctggatg cggaggtaac ctgcgtgctc atcggagagc gcccgggtct
    11041 tctgacgtcg gagagcatgt cggcatatat cgcctaccat gcaagaccgg acatgcttga
    11101 gtcggagtat acggttgtat cgaatatcag caggcatggt gtgccgccgg tggaggcggc
    11161 cgcgcatatt gcggatctga tcgcacagat cctggaaaag aaaaaaagcg gcgtagaatt
    11221 ttcaaaagca gaataaagac atggttgcga aggagcacag gcgggacgtc tgtgctcttt
    11281 ttctatagaa gcagcaagac ggacaaagga ggatacgtta tggagaaaaa cgaaggaggt
    11341 cagctggtgc gtgctctcgg actgaaagag tcgatcagta tgacgatagg aacggtagta
    11401 ggagtgggac tgtttacctg tggttcctca cagattggat atgtcggatc ggggattatt
    11461 gtaattacat ttttatccct gctcatctcg atctggccct gtctgatcta cggcgagatg
    11521 tcggcggcac ttccgtgtgc cggaggtact tacaattatg cgaagcgcgg actcaaccgg
    11581 gtctgggcga acctggcagg ctggcattac atcatctctg tggtcggcat cggtgcgggt
    11641 gagacactgg cattttccaa ttattttaaa attctgtttg gagaactcgg catcaatatc
    11701 gagggcgtgg attcgcggat cattgcgatt gttctggtcc tgtttttcct gatcttaaac
    11761 ttccggggaa ttgagatgtc cggaaaagcg cagacgggat tcattttctt cttctggggc
    11821 tgtgccgtgg catggttctt atatatgata ccgcacattc acctggacta tttcggcggg
    11881 atcgccatgg attccctgcc gccgtttaag gaaatgatgt acattttcgg actggtatgg
    11941 tggtgctata ccggatttga gacctgtgta tcgatgggtg cggagacgaa atatccgcag
    12001 tatacgcttc cgagagcgtt aaaagtatcg gtattccttg tatttgcagt caacgcgtta
    12061 ttccagtggt ttcttgtcgg actggtgccg cacgagtttt accacatcct tgcagtggca
    12121 gacgcaccgt atgcggaggg actccgggct gccggactgg tgggcttccc gatcattctg
    12181 ctctgcatcg gcattgcatt cggcggcgat ctctccacca tcaatccggg aattgcggca
    12241 ccggcgcgct acatctacac gatggcggag gacggttccc tgccgaagtt cttgtgcaag
    12301 gtacatccga agtataagac accgtatatg gcggttcttg tggtcggcat catcaatatt
    12361 atcctgattg caacagggtc aatcaattat atcgcgtcgg tatcgctgat ctcactcgca
    12421 gtatgttata tgattggctg tctggcttac cttggcttaa agaaacacta tccggatatg
    12481 aaccggccgt acagggcgcc ggcaggaacg gtcggatgct atgtcacgat tgcagcctac
    12541 actattattc tgattttcgc agaccgcata gcgcttctga cggcggcggt tgtgactgtg
    12601 gcagcgattg tctactgggc gcttttcacc agaaagcatg agaataagat tccgtccatt
    12661 gaggaggaga tcggtatcct cgaggagccg tccccccagg aaaaggcaaa gatggacaag
    12721 gagtaccgga tctggaaagc cggcacgatc cttgtgacgg tgatagcact tggcatttac
    12781 attattccgg tcttatttta aaatttaagg gattggaaag gagcacggta tgagacttta
    12841 tgagggtaac attttaacct gtgacaaaga gaaccggatt gcacattatc tgttggagga
    12901 tcaggggaaa atcctttact gcggggacga gctgccggcc ggctgtgtgg cggcggagcg
    12961 cgtgtccacc ggggaggggg cattgattcc gccgtttgtg gacagtcata tccatttcgc
    13021 aagttacgcg acgtttcatg ccgggctcaa tgtcatgaat gcgcggagca atgaggagat
    13081 tcttcagatg ctccgagagc atgtgaagaa aacgaaggaa aagctggtga tcgggtttgg
    13141 cgcatcgccg tattccgtgt cagacggaca tctggtgcgc agggtgcagc tggatgaggt
    13201 gtgtcccgac aaaccgctct ttctggtaaa gtatgacggt cacgcgtgtg tcgtcaacac
    13261 ggtgctgtta aacgaagtgc gcggcaaggt gcagcatctg cgcggttttc atgaggatac
    13321 cggggagatg aaccaggagg catttttcgc cgtctcggat tatatcacag cttcgctctc
    13381 tacggtgcag ctggtggcgc acatgcagaa ggcgctggac gatctggctg cgcgcggcat
    13441 cggcatgatt catacggtca gcggcgtcgg ctttgcgaga gatctggacg tcgatctgga
    13501 gcgttttttt gcgcgcggca tcacaaacgg catgcagatg cgcgtgttta tgcagacgct
    13561 cgatgtgaat aaggcggtaa agcggaagct tccgagaatc gggggctgtt ttgagacagc
    13621 gcttgacgga tgcttcggtt ccatggatgc ggcactgctc tcgccgtatg aaaacacgtc
    13681 ggactgcggc gtactctact attcggatga aaaagtgacg gaattctgta aggcggcaaa
    13741 ccgcgccggt ctgcagatcg agatgcacgc gatcggcgat aaggcgtttg tgcaggcggt
    13801 gcgtgccatc aaggcggcgc ttgacgatct gcccagagaa gatcacagac atacgatcat
    13861 ccatgcatgt ctgccgactg cggaggagat tgcggtctgt gagcggtatc acatcaatct
    13921 ggcagtgcag acggcgttca ttgactggcc gcaggagccg gacagctatc tggagcagat
    13981 cctcggagag cgtgcgggca ggctgaatcc gatccgcaca ttctgcgaac acggactgat
    14041 tttaagtgcg ggatcggacg gaccctgcac agatccggac ccgcttttat ggatgtataa
    14101 ggcatgcaat cacagcaatc cggcagaatc catctccgtg cagcaggcgc tgcgcatgtg
    14161 tacctacaac ggatattaca cgacctttga tgagagggag cgcnnnnnnn nnnaagcggg
    14221 gaaaatagcg gacatggtgt tgctggaccg caatccttac gacatcccga aggaggaact
    14281 ggcttccgtc aaagtgaagc agctctacct gcgggggcag gaatataaaa aaggaaacgg
    14341 cggcggagcc gcacagattc tgcgcggaat gataaagcgg ggaaaatgct gaccggcatt
    14401 tttcccagtt aggacaatct tacagacatt ttacatttcc cttttaaatt ttacacaaca
    14461 tacccgggca attttacaaa cctccgatat gatagaagaa ataagaagct atcatatcgg
    14521 aggtttttgt atacatggaa aaacagacac tggtatgggc gcaccgcggt gcaagcggct
    14581 acgcgcctga aaatacactg gaagcatttc agaaagcggt tgagatgggc gcagacggcg
    14641 tggagctgga tgtgcagctc acaaaggatg gagagctggt tgtcatccac gacgagacgg
    14701 ttgaccgcac cagcgatggc agcggctggg ttaaggattt tacatacgcg agaatttcca
    14761 ggtttaatta caaccggacg cataaggaag ggtacgagcg ggcgatgatt ccgacgctcg
    14821 aggaagtcta tgagctgcta aagccgacgg ggcttacgat caatgtggaa ttaaagaccg
    14881 gcgtggtctt ttatccggag atcgaa
//
