LOCUS       c00048_gnlPro..        22680 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HOMOEMGA_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:09:35
            Original ID  :: gnl|Prokka|HOMOEMGA_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22680
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22680
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6742:12680]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6743..12680
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..22680
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22680
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..98
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="ARERDSSNISILKHPFAAVALFTIDDLLFGI"
     CDS             complement(703..834)
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MSLRKIVSLSTDNSGHDISETVDANQCRMETSLPVTKQTAKSK"
     CDS             complement(1353..2942)
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILARVYLVMQNWDGAYNEAKIVYDQHSQLMTREQYRSGFDDMISGNYAEV
                     VWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGPIYSFLDYFVDEQFVKLFEEKEDR
                     YQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQSATRPEVCLMRGAEMLLIMAEAAA
                     QKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDINVERRKELICEGQAGFYDLVRLQ
                     KRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIGTLESNDYRFFCQIPQMEILNNDA
                     ISESDQNPWSGQ"
     CDS             complement(2961..5240)
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MNPNLEYVWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYF
                     FSGGYLDDQGYGNRQYYKRYSFRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANF
                     TTTLSSPWLRNEDNTGWVVSEKTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFD
                     NNMGHILSAQVNTEFTLPFNLKFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILAD
                     GGYASRYNFNKRSTTWNNVLSGEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGK
                     YELSNTTKNFGVSGGRDKYSLLSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTF
                     WSTGGSWRISKEGFMEDLKWIDNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTY
                     ESDDLYLKSGLKPSTYPTPDLKWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYK
                     ELPLSAQVGSASGYNMNIGDLRNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLP
                     TGPYTYSGTACTYKMEEGKSLYEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEV
                     TTDDFVYCGSAIPKVFGAITNNFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGV
                     IQELVEDRWRQPGDADVLIPRWSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSL
                     TRKALVENLRVYVTGNNLLTFGPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMV
                     GIQITL"
     CDS             complement(5237..6241)
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXISMKITYCMTAMGILT"
     CDS             complement(6743..7789)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="IlvN (E-value: 2.4e-48, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.6e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(7831..8562)
                     /locus_tag="ctg48_7"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(8599..9153)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_8"
                     /sec_met_domain="ALS_ss_C (E-value: 2.2e-18, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(9166..10866)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_9"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(10893..12680)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_10"
                     /sec_met_domain="ILVD_EDD (E-value: 4.6e-218, bitscore:
                     715.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGARALWRANGMKEEQFGKPIIAIVNSFTQFVPGHVHLHEIGQQ
                     VKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHKADAMVC
                     ISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLIDAMIEAADDSISDEQV
                     EKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVATHANRTRLFKKAAKMIV
                     DNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVLHLLAVAHEAEVDFTMK
                     DIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAGLVDGSVKRADGLTLNE
                     AIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELDTDRATGCIRDVEHAYV
                     KDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDAACEGILKDQVVSGDVV
                     VITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGGTSGLSIGHISPEAAAG
                     GAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTKAFTPPFRQRTVSKALK
                     AYAKMVASADKGGVRIVED"
     CDS             complement(13046..14398)
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="LFEGLAMEKLEQDWLEYPILHLDLNAERYSEASSLDSILQRHLNL
                     WEDTWGKDEREKTLSDRFIGVIRRAKARSGRRVVILVDEYDKPLLQAIGDELLQDEYRS
                     ILKPFYGVLKTMDGDIRFALLTGVTKFGKVSVFSDLNNLMDISMDDRYVEICGMTETEI
                     HAYMEQGVLDLTRNLQMDYEEVCMELKRRYDGYHFTHRSQGMYNPFSLLNTFAKSDFGD
                     YWFETGTPSYLVELLKHTDYDLYNMAHTETNADVLNSIDAVSRNPIPVIYQSGYLTIKS
                     YNPRFKIYTLGFPNQEVEEGFLNYLLPYYTSVNVIDTSFQLFKFIKEIESGDVDAFLSR
                     LQSFFADTPYELIRNLEVHYQNVLFIVFKLVGFYVKVEYRTSRGRIDLVLQTDHYIYIM
                     EFKLDGTTEEAMRQIEEKQYALPFASDERKLFKIGVNFDNETRNIAGWSVD"
     CDS             complement(14669..15265)
                     /locus_tag="ctg48_12"
                     /transl_table=11
                     /translation="VVVVCNVLVAGCASGKVFDRVEKIPHRKVGLLLGTAPVTPWGTKN
                     LYFTYRIDAAVKLFHAKKVDYFIVSGDNHSTDYDEPTCMRDSLVACGVPDERIISDYVG
                     FRTLDLEVRCKAIFGQDSVTVISQSFHNERAIYLAGHNQIDAIAFNAQDVTSVWTTWLR
                     GHSRELLARVKIFIDLIIGKQPRFWGEKVKIPEIR"
     CDS             complement(15787..17022)
                     /locus_tag="ctg48_13"
                     /transl_table=11
                     /translation="VKFKQALIIMEKLDDMKLTVLYIEYRNFFIDVLSRFYGFEKYDIY
                     HYSEILNVDELCRNEALNWDMYLIEFWGKEKINWEYLSGNKCLSWTADLFDKYYDYWEW
                     DILSSNEGIFWNELLLNKYKSKLNWNLLSLNKSLPWSIDFINRYVDRLNWVNLSANLSL
                     PWSDYLLEYYENLWDWNLISANPSLPWTDDLIIKYMDRLNWAGLSMNPALPWSSEFIQK
                     YKYNWIWGYSSDWVMTDDIGLCGNSGIHWNEELIEMFDGFIDWGELSLNTGDMWNECLI
                     DKYLCKLHWEECWCPPLGMGGLSSNPSLPWSLDFVDKYKPYLNIKEICSNMSFPWREED
                     FRNNNGGIINDCDKSYWKLLSMNEGLPWSVGVLYDNRCWFDWNLMKGNVKVYDNCLSVL
                     EKEKMKFLLELV"
     CDS             17489..17638
                     /locus_tag="ctg48_14"
                     /transl_table=11
                     /translation="VDTDSYPLGKNHSSSHSHVSSADTTMPAGWDSSTGMTVHLPYNVH
                     TNRV"
     CDS             complement(18049..18573)
                     /locus_tag="ctg48_15"
                     /transl_table=11
                     /translation="VGEISQRYGNRLAGLWMDDGIGYYPNGASFEKIAKAAKSGNKELA
                     ICFNSWILPKLTDFQDYYAGELGLSLASAGVNDPSLPLDGDGLFHGGPQDGLQATFSGT
                     LEPGDWTHIYKDSIIGDPVLSIDELTQVVKESNKRKNLPMINVRIYQDGTISPKSYALL
                     KELNNRISKGE"
     CDS             complement(18573..19577)
                     /locus_tag="ctg48_16"
                     /transl_table=11
                     /translation="MKGRSELLLIGPSYIRKIRMKKQFIYFLSLFVMCLAACSNPVDPT
                     ALNLDSANINRLIPFRGELNNGVKQLYPEEPYKAFWAENWKTPEQSISWKVNTDGEDYM
                     AEMIVSVNRMGDGEETELVLSNGTDSVICRINTTGWQRCRFPRPLHFNKGTSVLSLKIG
                     KPGKQDDFNVYLYSLEVTRPETYEQLRAEATSLRSNTSWMADLPYGFFFHWNSKSMPQS
                     GEPLAYEDAVNNFDVDRFARTVYECGGKLIFFTTSWAEYYFPAPIQAIDSILPGRTTKR
                     DLVADLSDALGKYGXXXXXXXXXXXXVMEIKNGGTSSIIHVIMQEICLQMWKR"
     CDS             complement(19592..21025)
                     /locus_tag="ctg48_17"
                     /transl_table=11
                     /translation="MKTLIKNILLAVPVILSASCSDWLEEDPKTFISPSSFYQTVEDFD
                     GALKGLYPQGQNLNLTEVFADYNDKPESAEQVGDIWANNPGYGFYAFRNAWSGPYSTIK
                     NANMILESIEDKDFTAETKNRIIGEAKCLRAWSYFTLVQFFGDVPLRDKVVTSDADVAI
                     DRTPQADIYQFIFDDILDAEQKLPEEAQDMGRVNKWVVKAIMARIYLTSAGFPMNQKEN
                     YAKAKEKALEVINSGQYSLMPTFDKVFKTERYTAETIWAQLFSAPDSYSGMHNESSPIG
                     SQTALYLPTDAFIASFDKGDMRKEWGIKPEYVNAKGNKVIARTYYNKYINEEYLEQELP
                     ASNTNILTWQTQLIRLAEMYLIAAEAENEINGPAGAYQYINAIRKRARVDQNDPTNVPD
                     LSGLSQDQFREAVLLERQHELYEEGFAWYDLKRTQTFDKVQKARGSRLNVPIGAYNNTW
                     LIPDTEILNNNIPQNPDYR"
ORIGIN
        1 gagcacggga acgggatagt tcaaatattt ctatattgaa acatcctttt gctgcggttg
       61 ccttgtttac tattgatgat ttactttttg ggatataaaa gccaagtcct atccggagaa
      121 catactattg gatacaaagc gtcaggagag ttcctggaag ttaaaggatt gtcaaaatga
      181 tattttatgt atgtgctgaa ggaattgtac gggcaaaggg aaatgtcgat ctgtttttat
      241 agaaatctcg ccgacttacc tttgttcgct ttgacctgat tgttgcaata ttcatatcac
      301 aaaaaatgta tattatctat gattgttacc catataccac atctattcat aatttattaa
      361 catattgcta ttttacacac acatcaaaaa gcggttgctc tggaaataaa aactgtctaa
      421 aaacatatga ttttcttttt taaaagcact aattgaggtg tttttcttct ctaaacgaat
      481 aaaaactcca ctacaataga aatttatctc agtttaaacg aaattgaaat ctgtttaaac
      541 taaaattttc ttcggtttaa acgagataaa aagtcgatat cagatatctg ttatgttaat
      601 aaatgtatgc ttcccttttc tagaatgaac aaataaaaaa taagtctgtt tcctccaaag
      661 gccatttaca ctcataatat tcatatatca ttcattttta tatcattttg attttgccgt
      721 ctgtttggtt acaggaagtg aagtttccat acgacactga tttgcatcaa ccgtttcact
      781 gatatcatgt ccactattat cggttgaaag agaaactatt tttcgcaatg acatacgttt
      841 actggtaatt ctggatcagg tgaaaatact ggattccacg catcgccagc gcctgacctt
      901 tgatgtgttt tttctgtggt acaaatatta tcaggcaact ctttccgata tttattatga
      961 gagataaacc ggatttattt tctactaacc ctttcgacat acgaaaaaag aagtaatctg
     1021 gagccggaag taatcgaaaa gattgccaaa gcattagata tacccgaaga agcaattacg
     1081 gaactaggcg aagccacttc cattaatatc ttttccggca cctggcaaga taatgctaat
     1141 tgccagaatt ataatcctac atttaacccc ttagaaaaag tcgttgaatt atacgaacgt
     1201 ttattgaaag cggagcagga gaaggtggcc atgttacagg aagtgctaaa ggacaaaaag
     1261 taaaacagtg aacatcaaat gttacaaata aaagagaggg aggcatgtaa taaacacctc
     1321 cctctctttt atttatttac aacagatgaa acttactgcc cgctccacgg attctgatct
     1381 gattcggaga tcgcatcatt attcaggatt tccatttgcg ggatttggca gaagaaacgg
     1441 taatcgttcg actccagcgt ccctatcggt tgcggatcga gcgcattata tccgttcaga
     1501 tactgcatgc cccatacgta atgtccggca ggattggtag ttgattcacc gatacgaacc
     1561 aatctctttt gcaggcgcac caggtcataa aaaccggctt gtccttcaca gatcaactct
     1621 ttacggcgtt ccacattgat gtcttccagc aaagcttcgc ctccggcatt ggttgtcggg
     1681 gtagcattac gcgccacctg caaacggttc agcagattca gagcctcgcc ggagttaccc
     1741 ttttgggcag cagcctccgc cataatcagc agcatttcgg ctccgcgcat caggcagact
     1801 tccggacggg tggcgctttg aataacgctt ccgccgtctt caccataatg cttgtatttg
     1861 tcgaaagccc attttgtatt gatttccgta ttcgcattgt tcgtacgttt ccagaactgg
     1921 taacggtctt ctttttcttc aaatagtttc acaaactgct catccacgaa gtagtcaagg
     1981 aacgagtaga taggaccatc ggcataaccc tcgccgtagc tggcatcctg gttataccag
     2041 aaattgaact gcgtactacc gcccaggtta ttatcggcgg tatatttcat ggcccatacc
     2101 acttccgcat aattgccgga gatcatatcg tcgaaaccgg aacggtattg ttcgcgggtc
     2161 atcaactggc tgtgctggtc gtagacgatc ttggcttcat tgtaagcgcc gtcccagttc
     2221 tgcatcacca gataaacacg ggccaggatt cccgaacata ttttggagtt gatcagccac
     2281 atatcgtccg gattataatc ggcaagcaat gttttagccg tcgtcaggtc ggacacaatc
     2341 tgggtataga cttcctctac agtagaaaaa cctttatggg attcatcatc ggaagaggta
     2401 cgcaggatca ccccacgctt gcttttagct atcgcatacg tctgctggta attctggatc
     2461 agatggaaat actggattcc acgcatcgcc aacgcctggc ctttgatatg ttttttctgt
     2521 gtttcatcac cggcggcggc atccacattg gtcaggatga tattggcacg gttgatcaca
     2581 ttatagcaca tcgaccagat ttttgaggca tttccgtcag cctgtgtttt tgagttggaa
     2641 tactggtatg ctgttacctg atcacctccc atattggtat ggctgatcac gtcggcacca
     2701 ctcgcatcga catacatctg gaatccggga agaccggcat acacacggtc tcctttatca
     2761 gtattaaaat acagctgctt ataggctgaa gtcaatactt tttccaactg ggagacattc
     2821 cccagtacat cttcatcgtt tactttcacg taggagctgg ttgtcaggtc gtcgttacat
     2881 ccggtcaggg ccataccagc aaaaaccagg gacaggaagg atatatttat aaatcgtttc
     2941 ataaatatca ttttttacgt ttacaatgtg atttgaatac cgaccatata cagtcttctc
     3001 gaaccctgaa taccgttatc ggtttcagca ttaccgttat aactgttacc cattatacct
     3061 gtttcggggt ctgtgtagcg ttttttggca ggaccgaaag tcaacaggtt attaccggtt
     3121 acataaacac gcaggttttc taccagggcc ttgcgggtaa ggctcttagg cagcgtatag
     3181 cctaatgtca ggtttctcag acgccagtag tggttgtcga atacgaagtt atctgcatat
     3241 tttaccgtcg cgccatactg gttgtacgac caacgtggga taagcacatc cgcatcgccc
     3301 ggctgacgcc atctgtcctc aaccaactcc tgtatcacac cgacacccgg acggttcatg
     3361 atacgttctt tatatgtata gtccgatatt ttggaaccat aagaataata gaacatgaac
     3421 gacaggtcga tccctttgaa ctggaagtta ttggtgatag caccgaacac tttgggaatc
     3481 gcggagccac agtacacaaa atcgtctgtc gttacttctt cctgcttttc cgtacgtttc
     3541 caaccgccgt taccatcgcg gatcaaccag ccgggtactc cggtttccgg attaacaccg
     3601 tcgtactggg gagcgataaa ttcatacaga gacttgcctt cctccatctt gtaggtacag
     3661 gcggtaccag aataagtgta aggacctgta ggcaaataag tcacctcatt tttcagcgta
     3721 ctcatgttgg catcgatatc ccatctgaaa tctttcgttg taaggatatt cgcattcaat
     3781 gtgatttcaa tcccgctatt acgcaggtca ccgatattca tattataccc ggatgcacta
     3841 ccaacctggg cagagagagg cagttcctta taatacaaca agtcatggga agtacgggaa
     3901 taatattcca ctgtaccgct aagtcggttg aatacggaaa aatctaaacc gatattccat
     3961 tgctgattac tttcccactt caagtccggt gtcggatagg tagatggttt taaaccggat
     4021 ttcagataca ggtcatcact ttcataagta ccctggtatc cgtaaaggac ttcatcccct
     4081 gccttaccat tcgattcacg cacgatcagc ttatcattac cagtcgtacc gtaactacca
     4141 cgcaacgaaa ggttatcaat ccatttcagg tcttccataa aaccttcttt cgatattcgc
     4201 catgaaccgc ctgtcgacca gaatgtaccc cagcgatgat cggagctgaa acgggaagaa
     4261 ccatcctcac gaagtgaagc ggacaagtaa tacttattca agaagttata atcgacctta
     4321 ccaaagaacg aaagcagaga gtatttatca cgtccgccgg aaacaccgaa gttcttggtg
     4381 gtattcgata attcatattt acccagttcc atgatacctt caccccaacc ttgttcgtag
     4441 tgggagtccc aggtatacca ctcatgtccg accagacctg aaatcgtatg gtcaccaatc
     4501 atccattcac cagacaatac attattccag gtggtggaac gtttattgaa attataacgg
     4561 ctggcataac caccgtctgc cagtatagaa ataccataag gtgcagtctg tccgctgcca
     4621 tgtacggcgg aagtatattg catggtacga taccagtaat cgtcaatatt caaagccgaa
     4681 cggaatttca ggttgaaagg aagagtaaac tctgtattta cctgagcaga caggatatgc
     4741 cccatattgt tatcgaaact gtcatcgttc ggattatccc aataatcacc cgagttattc
     4801 aggatatggg caccaaagaa gttattggta tatttaccgt aactgtacat ccgttcccct
     4861 gttttttcag aaacgaccca accggtatta tcttcattac gtaaccaggg tgaagacaaa
     4921 gtcgtcgtaa agttagccgc acggctggca ccaccggaaa ggttctggcg atgacgcgaa
     4981 taagaaaggc taccggccac tttccaccaa tcgaacaact ctgtactcag gttggtacgg
     5041 aaagaataac gtttataata ctgccggtta ccatatccct ggtcgtccag ataaccgccg
     5101 gagaagaaat aggctgtttt tccaccattg gcctgaccac ttatatccac actataatcc
     5161 tggcgcagtt tacgggagaa gatagctttg tagacatccc aatcatcttc atcccagaca
     5221 tattccagat taggattcat gtaaggattc ccattgccgt catgcaatac gtaattttca
     5281 ttgatatnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngc atattcatgc
     5401 cgtcataaag aagggcatca taatacaagg cataccaggt attttccagc tgctggtacg
     5461 gatcggcttt tttcggattc ttgacagcat tatccgaagt accccaacct ccgcggaagt
     5521 taatacgcgg tttttctgat ttaccccgct tggttgtaat cattacgacg ccgtttgctg
     5581 cacgcgaacc gtagagcgaa gtggccgccg catccttcag caccgtcatc gattctatgt
     5641 ccgtaggatt gatctgattc agttttccat cgtaaggcat cccgtccaca atatataacg
     5701 gatcggcctt tccggacatg gaagcaatac cacggatctc cacacgggca tcagctccgg
     5761 ggttaccctg tacattcaca acattcacac cggcactcat cccctgcaat gcttccgcaa
     5821 agccggagcc catgatcttt tcgagttttt cagcttttac aacggaggcc gatccggtga
     5881 aggttgattt cttagccgtt ccataggcta cgacaacgac ttcatccagg tcctgtgtcg
     5941 catcacttaa ttttacattt aaaatagatt gtccgttcca agtgatctcc tgagtggcca
     6001 ggccgacaaa ggaaataaca ataaccgctc cccgccgaac attatccagc gtaaactttc
     6061 catcgatatc ggttatcgta ccgatagtgg ttcctttcac tacaacagaa gctccggcga
     6121 caggtcccat ctggtcctct accaggccgg ttaccttatt accctgttgt actaccatcg
     6181 tttccggacc tgtaggattg gcagcaatcg cacctgccgc acctaataat acagaaatca
     6241 ttagtgatct aattagtttt gagttggtcc acatagctaa attcaagtct ttaattaaat
     6301 aaaattaatc acaatagcgt tcatttcatt agaggttaca cttttctaag ataaaagtga
     6361 ctggcataca tttcaataaa ataaagttaa ctaaaacaaa gatatactga tcattacaca
     6421 caacatcctt ctatatttcc actctacaaa ctacagtatc tccatcagca aatataactt
     6481 atcattattt aatacaagca taattatgta tatttattgc tctaataaat atattttaac
     6541 caccatttaa ttgatttttt tatctaaaat ccacattcaa acaatgacat acatattggg
     6601 atgaaaaatc aataacagtt gcaatcaaaa acatttttta accattaacg cattacataa
     6661 accataaaaa aacggcaacc cgaaaagccg gattgccgtt tttatatcac aaaatgttta
     6721 actattaatg tatcaccatt tattagttgt tttcaggacg aagtttacga acaacagcac
     6781 ctgcacgcca catttcactt tcgcgaagag cagccagttc tttttccaga ccttcacgat
     6841 agtcaggctt gctgtttgtg tcgatagaac gctgtgcttc gttaccgcag gcaacttcgc
     6901 tatacaactt ctggaacacc ggttttgtag catcgtggaa cgggcccatc cagtccaaag
     6961 caccacgctg tgcagttgtt gaacagtttg catacatcca gtccataccg ttttctgcga
     7021 acaacggcat caatgactga gtcagttctt ctactgtttc attgaatgct tcagaaggtt
     7081 cgtgaccgtt ttcacgcaaa gtttcgtact gagccaacag taatccctgg atagctccca
     7141 tcaaagtacc acgttcgccg gtcaggtcag aataaacttc tttcttgaat gttgtttcaa
     7201 acaagtaacc agaaccaaca ccgataccca gtgcaatcac gcgatcccat gctttgcctg
     7261 ttgcatcctg gaagattgcg tagcttgagt tcagaccacg accctgcaag aacatacggc
     7321 gcagtgaagt acctgaacct ttcggagcaa ccaggattac gtctacatca gcaggaggga
     7381 tgatgtttgt acgttctttg taagtgatac cgaatccgtg agagaaatac aaagccttac
     7441 ccggagtcag gtattttttg atgcgcggcc aaacttcaat ctgagcagca tctgaaagca
     7501 gatactggat gatagttgct ttttcgcatg cttcttcgat atcgaacagt gtttcgcccg
     7561 gtacccaacc gtcagcaacg gccttttccc aggtcttacc acctttacgt tgtcctacaa
     7621 ttacgttaaa accgttgtcg cgcaggttca ggctctggcc aggaccttgt acgccgtaac
     7681 ctattacagc gattgtttcg tctttcaata cttctcttgc cttttccaac ggaaattctt
     7741 cgcgggttac tacgttttcg tcaacgccgc caaaattcat tactgccatt ttctttttac
     7801 tattaaaatg tatataaaat aatttgtttt tcagatccag gtaacggcag cgcggctgat
     7861 ggctttgccg tcgttacaga ttgccatatt atatttatcg agggatactt cctggttatg
     7921 gagagtcagc tccatcccat actttccttc ggactgataa gctatttcga aacggcttat
     7981 ctctttttct cggaacagac tgatatcgaa caagtcgagc aggtgttcca tgtatttgat
     8041 actgttcagg tggccgttta cgtccaggtc actatacttc acacggtaag gttcgccgga
     8101 agtgttgttt tccaccggag caattttacc cggtttttca atcggacagg gacggtcggt
     8161 gatataagca ctcaggccct ccacatcgag caaggtcggg cggcgggttt ccatatcgat
     8221 agccgcccag atagagcggg caaagccaaa ggtcttgcct tcgccgttca ccagttcaaa
     8281 gcaacggctg gtaaacaact taccgacctc atccacccag gtatataaag ttacggattc
     8341 agacatggca ggataagaag tcatctcgat agccagacgg gaaagaaccc aggcggtatg
     8401 cctttcggtc atatcgttat atccgaatcc acggtcggcg gcatggcaag aagcagcatg
     8461 caacaaataa gttccgatca tagggattgt aatacgtccc cggaagtccg tcagataaga
     8521 ctctgttacg aaatgaaatt ctcctacttt gttcttctcc ataatttact ttatttacaa
     8581 aatgtttcct tattattctc agacatgttt ttcctgcaac ttcttttcca ttgcagataa
     8641 catgtcgctc agacgttcta ccttactctt cgttatagca acgcgtccgg aacggataaa
     8701 ttgcaggaca ccgatcgtct cactcaattc tttaaacaaa gcctgtgtct catcataatg
     8761 accactcttt tccaacacca cacaatcctc attcatttca aggatacggg cattgtactt
     8821 acggatcaga tcctcaaccg tccccatctt gataaagagt tcggtactca gtttataaag
     8881 agcgatttcc tggtaaacca ggtcttcatc cgtattataa taggctttca ggatatccac
     8941 acgcttgtcg atctgtttta cgaccttgtc gatcgtatcc tcgtcggcaa aggtagtaat
     9001 tgtaaactta tgtattccct ttatagcaga gggagaaaca gaaagcgtct caatgttcag
     9061 ttgccggcgc gtaaagataa cagttatctg attcagaaga ccaacagtgt tttccgaaaa
     9121 gataataacg gtatataatt gttttgtatt catagtttct cctccttact tatcacccaa
     9181 aatcatgttt gtcacgcttc ctccggccgg aaccatcgga tataccatac cacaagtttc
     9241 cacattggca accaacatat aggcaccatc gtgattcaac atttcagcaa tcgcctcatc
     9301 caagtcttcc cgtttatcta ccgcacggga agcaatacca aaagccttgg ctatcgctac
     9361 aaaatccgga ttcttcatga tggtattcga ataccgttcg ttgaagaaca gctcctgcca
     9421 ctggcgtacc attcccagga aattgttgtt aagaacgatg atctttacat tcagattttc
     9481 ctgcatgata gttcccaact cctggatagt catctggata ccaccgtcgc cggtaaagaa
     9541 acagaccgta cggtcaggcg ctcccagctt cgctccaatg gcggcgggaa ggccaaagcc
     9601 catcgttccc aaacctcctg aagtaactac gctgcgtgtt tgtttatatt tgaaatagcg
     9661 aacacccatc atctggttct gacctacatc cgtaaccaga atcgcatcat tatcggttgc
     9721 ttcggaaacc ttacggacta cttcgcccat tttcagttgg ccttcggtag gatagagttc
     9781 tttttctatt accttattat attcctcttt ttcatccggt tcgaattcag cattccattc
     9841 cggacgcttc cgttcttcca gtaaagccgt aatcatcgga atcgtatgct tggcatttcc
     9901 cagcactttc acgtcgaccg gcacattctt tccgatctcc gaattgtcga tatccaggtg
     9961 gataatcttt gcctgcttgg cataagtctt caggtcgccg gttacgcgat catcgaaacg
    10021 cataccgata gcaatcagca cgtcacattc gtttgtcttg cggttcggtc cgacatttcc
    10081 atgcatcccc aacatacctt tatttaatgg gaagtccgaa ggtaatgcag acaagcccaa
    10141 tacggtagaa ccggctggta tatcgttttt caacaagaat tctttcagtt cttcttcagc
    10201 tcctcccagg ataaccccct gccctaccag acagaatggc tttttggcat tatttatcaa
    10261 tgaagcagcc gcctcgatac gttcctccct gatatccggt tcaggttggt aactacgaac
    10321 ataatccact ttctgatact cataatctac caaacccacc tgtgcatctt tcgccaaatc
    10381 cagtaccaca ggtcccgggc gaccggtcga tgcgatatag aaagcacggg aaacggccca
    10441 agcaatttct tccgggcggc gtatctggta agcccatttg gtaatcggtt gtgtgatacc
    10501 gatcacatca acttcctgga aagcatctgt tccaagcagc ggagacggaa cctggccggc
    10561 aatcaccacc atcggtgtac tgtccatcag cgcatcggca ataccagtga tggtattggt
    10621 tgccccggga cccgaagtaa ccaccgttac tcccactttt ccggaaacac gggcatatcc
    10681 ctgtgcagca tgtgttgcac cttgttcgtg gcgcaccaga atatgtttta actgatctct
    10741 gtaatcgtat aaactatcgt aaattggtat cgcctgccca cccggataac cgaagatagt
    10801 atctactcct tcagcgatca gcgctttcag caaagcttcc gaaccggtta tcttttgttt
    10861 gtccatctct aaaatatagt atttggtgtt tattaatctt ctactattcg tacaccgccc
    10921 ttatcggccg aagcaaccat ctttgcatat gctttcagtg ctttcgatac cgtacgttgg
    10981 cggaaaggag gtgtaaaggc ttttgttccg cgggcttctt ccgcttcacg gcgtttggcc
    11041 agttcttcgt ctgtcacctt tacatgtatg gttctttcgg gaatattaat ttcgataata
    11101 tcgccgtctt tcactaagcc aatcgctccg cctgcagccg cttcgggaga aatatgtccg
    11161 attgacaaac ccgatgttcc accgctgaag cgtccgtctg tgattaacgc acattcttta
    11221 cccagatgtt tactctttat ataagaggta ggatacaaca tttcctgcat acccggacca
    11281 cccttaggac cttcataggt gataacgacg acatcgccgg agacgacttg atctttcagg
    11341 ataccttcgc aagcggcatc ctgcgaatcg aatactttgg cagggccggc aaaacggaag
    11401 atactttcat ctaccccggc tgttttaacc acacaaccgt cctgtgcaat atttccatac
    11461 agaacagcca gaccgccgtc tttcacataa gcatgttcca catcgcggat acatccggtt
    11521 gcacggtcgg tatccagttc tttataataa ctttcctgcg atccgagcac cagattgaaa
    11581 cggtgggccg gagcactttt ataaatattg attgcttctt ccgttacatt tacagaggta
    11641 atgcagtatt ggtcgatagc ctcattcaaa gtcagaccat ccgcacgttt cacggaaccg
    11701 tccaccagac cggcttttac cagctcattc ataataccga taatacctcc ggcacggttc
    11761 acatcttcca catgataaga acaactcgga gccactttac agataaccgg tgttttgcgt
    11821 gaaagcatat cgatgtcttt cattgtaaaa tcgacttccg cttcatgagc cacggccaac
    11881 aggtgaagga ctgtattcgt cgatcccccc atggcaatat ccagcgacat agcattcaga
    11941 aaggcctgac gggtggcaat actgcgaggc aatacggaat catcgccgtc acgataatat
    12001 ttaaaggcat tatcaacaat catcttcgcg gcttttttga acaggcgggt acggttggca
    12061 tgtgttgcaa caactgttcc gttgccggga agagccaatc caatcgcttc gttcagacag
    12121 ttcatagagt tagccgtgaa cataccagaa cagcaaccgc aggtcgggca agcggaacgt
    12181 tccacctttt ctacttgttc atcgctgata gaatcgtcag ccgcttcaat catggcgtcg
    12241 atcaaatcga gtgcacgtcc gtccagatta ccggcttcca tcggaccgcc ggatacaaag
    12301 attgtcggaa tattcagacg catactggcc atcagcatac ccggagtaat cttgtcgcag
    12361 ttactgatac aaaccattgc atcagcctta tgcgcattca ccatatattc cacactgtca
    12421 gcaatgatgt cgcgggaagg cagagaataa agcattccgt cgtgtcccat agcaataccg
    12481 tcatcaatag cgatcgtatt aaattctgcg gcaaagcaac cgagcttttc gatttccgct
    12541 tttacctgct gtccgatctc gtgtagatgc acatggcccg gtacaaactg ggtaaatgaa
    12601 ttcacaatgg caatgatcgg tttaccgaac tgttcttctt tcatgccgtt ggcacgccat
    12661 aatgcacggg ctccggccat acgtctgcct tctgtgctat aggagcttct taacggattc
    12721 ttcatcatat ctgtttttat cttttagtca ataaaaaagc ccttctctat atggagaaag
    12781 gcttaagaaa tatcttttac gacttcacaa cttcttacac acctttctcc ttacctacta
    12841 atgactagaa ggaccaccac gagaataata tgtaatacat tgttcatcat cttttcttat
    12901 cgtctttatt ttgtttgacg ctgcaaatgt agaataataa tttgtacgag caaaggattt
    12961 aaaagaaaaa tcttactttt tctttcattt atcaataaaa gagggcggtt catcttgcat
    13021 tttaacagta ttattaaaat ctacatcaat cgaccgacca accggctatg ttccgtgttt
    13081 cattatcaaa gttcacccct atcttaaaaa gtttccgttc atccgaggca aaaggcaagg
    13141 catactgctt ctcttcgatc tgcctcatcg cctcctctgt cgtgccatcc aacttaaact
    13201 ccattatata aatgtaatga tcggtttgca acaccaggtc aatgcgacca cgggaagtac
    13261 gatattccac cttcacatag aaaccgacca gtttgaagac gatgaacagg acgttctggt
    13321 agtgcacttc cagatttcga atcaattcat atggcgtatc ggcaaaaaaa ctttgcaacc
    13381 ggctaaggaa agcatccaca tccccagact cgatttcttt aatgaattta aaaagctgga
    13441 aggaagtatc aataacattg acagaagtgt aatatggaag caaataattc agaaacccct
    13501 cttctacttc ctgatttgga aagcccaatg tatatatttt aaatctagga ttataggatt
    13561 tgatcgtcaa ataaccactt tggtaaataa ccggtatcgg gttacgcgaa acggcatcga
    13621 tactgttcaa cacatctgca ttcgtttccg tatgtgccat attgtacaag tcatagtcgg
    13681 tatgcttcaa cagctcgacc aagtaagagg gggtacctgt ctcaaaccag taatctccaa
    13741 agtcagactt cgcaaatgtg tttaacaaac tgaacggatt gtacatgcct tgcgacctat
    13801 gagtaaaatg ataaccatca taacggcgtt tcaattccat gcaaacttct tcataatcca
    13861 tttgcagatt acgagtcaaa tccaacaccc cttgttccat atacgcatgg atttccgtct
    13921 cggtcatacc acaaatctca acataacgat catccatcga aatatccatc aaattgttca
    13981 aatcactgaa cacacttact ttaccgaact ttgtcacacc tgtcagcaaa gcaaaacgga
    14041 tatcaccgtc catcgtcttc aacaccccat aaaacggttt taatatagaa cggtattcat
    14101 cctgcaacag ctcatcccca atagcctgca acaaaggttt gtcgtattca tccaccaaaa
    14161 tgaccacacg ccttcccgat cgagcttttg cccggcggat cacccctata aaacgatcgg
    14221 acaaagtctt ttcccgttca tcttttcccc atgtatcttc ccacaggttc aaatgacgtt
    14281 gcaaaatact atccaaggac gaagcctccg aatacctctc cgcatttaaa tccaaatgca
    14341 atatcggata ctccaaccaa tcctgttcca gcttctccat cgccaatccc tcgaacaact
    14401 cctccttacc ctgaaaatag gcctccaaag tcgaaaccaa caacgatttg ccgaaacggc
    14461 gcggacgact caggaagtaa taactcccgg tcttcaccat ttgataaatc aacgctgttt
    14521 tatcaacata gagatacccc tccttacgaa tcttctcgaa attttgtatg ccaataggat
    14581 aaagtgcagc cataaaccgt ttttatatta tctatcaaga caaaggtaac ttatttttta
    14641 tcaataagta tcttattata ttacattttc atcggatttc cggaatcttg accttctccc
    14701 cccaaaaacg gggttgctta ccaataatca agtctataaa tattttaacc cgagccaaaa
    14761 gctcacgact atgtcccctc aaccaggttg tccacacaga agtcacatct tgggcattga
    14821 atgcaatcgc atctatttga ttatgacccg ccaaatagat cgcacgctcg ttatgaaaag
    14881 actgcgaaat aacagtaacg ctatcctgtc caaaaatggc tttacatcgc acttccaaat
    14941 caagcgttcg aaaaccgaca taatccgaaa taattcgctc atccggtaca ccacaggcaa
    15001 ctaacgaatc acgcatacaa gtcggctcat cataatctgt tgaatgatta tcaccactta
    15061 caataaagta atcaaccttt tttgcatgaa acaatttgac tgccgcatca atacgatacg
    15121 taaaataaag atttttcgtt ccccaaggag taaccggagc agtccccaac aacaaaccga
    15181 ctttacgatg tggtatcttt tccaccctgt caaatacctt acctgaggca caacctgcca
    15241 ccaacacgtt acaaactaca accactatgt ttatgacaga aatgagcaga aataatggtt
    15301 aattgtatga ttttcttctt actttgaatt actttttttc acagacttgc tcttttatta
    15361 taaaggattg tcaccaacaa aataacaatc ctaataaaac aatctatttc ttcttaggaa
    15421 tatttttgta aaaggcatat agcaaaggta ttatttccag acatatccaa agccataagc
    15481 atgtcatatt tcatttgaca ggaaagcttc cgtcttcacc aatcattacc ggataaaaca
    15541 tatcatccct gcaaagaacg attgctccaa cctatcagag taatataaat tttgcagact
    15601 gtattaacta ataatatttt cactgtcccc aaaatacgat gtcatatttt tcaacacacg
    15661 atctttactt gtattagcat agcaatagac ttttctataa aatataggcg catattcttt
    15721 tcttcagctt cgtcacttat ataactatcc tacccaatca tccacgacca ttttttgata
    15781 cttcaatcaa actaattcaa gtaaaaattt catcttttct ttttctaaaa cacttaaaca
    15841 gttatcgtat actttcacat ttcctttcat tagattccaa tcaaaccaac atctattatc
    15901 atatagtact cctacagacc aaggtaaacc ttcattcata ctcaataatt tccagtaaga
    15961 tttatcacaa tcatttatta ttccaccatt attatttcta aaatcctctt cacgccaagg
    16021 gaaagacata ttagaacaaa tttcttttat atttaaataa ggtttatatt tatccacaaa
    16081 gtccaagctc caaggcaatg aaggattact actgagacct cccataccca aaggaggaca
    16141 ccagcattct tcccaatgca atttacataa atatttatca atcaaacatt cattccacat
    16201 atctcctgta tttaaactaa gctctcccca atcaataaaa ccatcaaaca tctctatcaa
    16261 ttcctcattc cagtgaatac ccgaattgcc acataaacct atatcatcgg tcattaccca
    16321 atctgatgaa tatccccaga tccagttata tttatacttt tgtataaact cagaactcca
    16381 aggtaacgct ggattcatac ttaatccagc ccaatttaaa cgatccatat atttaatgat
    16441 taaatcatca gtccaaggca acgatggatt ggcacttatc aagttccaat cccataaatt
    16501 ctcataatat tccaacaaat agtcagacca aggcaatgac agattagcac ttaaattaac
    16561 ccaatttaat ctatcaacat agcgatttat aaaatcaatt gaccacggta acgatttatt
    16621 taagctcaac aaattccaat ttaacttaga tttatactta ttaagcagca actcattcca
    16681 gaatattccc tcattagaag acaagatatc ccattcccaa taatcataat atttatcaaa
    16741 aagatctgct gtccatgaca aacacttatt tccactcaaa tattcccaat taattttttc
    16801 tttaccccaa aattctatca gatacatatc ccaatttaaa gcttcatttc tacacaattc
    16861 atcaacattc aaaatttcac tataatgata tatatcatat ttttcaaaac cataaaatct
    16921 acttaataca tcaataaaaa aatttctata ttcaatatat aatacagtta atttcatatc
    16981 atccaacttt tccataataa ttagagcctg tttaaatttc acagtttgaa ataaataaag
    17041 tgtttcctct ttctgctaaa ataattattt ttaattacta agtttcaaat aattatgtat
    17101 tgtacggatt tagaagaaac acagtggcaa gttatcaaga aaatcttgaa cttgcaagaa
    17161 agaaagcgaa aatacagggc aaccgcacca aaatagttct cgcccgaaag aaaacggatg
    17221 gggaaatgtt ctttttttga taagtgnnnn nnnnnncaac acaaaacacc gttttacata
    17281 attgaaatgg tagtttaaaa tcaatgagaa agtccgcgac ggaaacaatc ttccccctcc
    17341 atggttttca tacctctgcc ttcacactcg taacacactg tattatatcc ttttgtggtg
    17401 aaaccagcct tttcactatt gtttttggaa ccgtaacagg aacccttccg atgagtaggc
    17461 atctgtgggg aaatagatag ttatctatgt ggacacggat agttatccgt tggggaagaa
    17521 ccactcgtct tcacacagtc atgtgagtag tgctgacact acgatgccgg ccggatggga
    17581 tagcagtacc ggtatgacgg tacacctacc ctataacgta cataccaata gggtataggg
    17641 taccggacgc tactttacag ggtataatct gccggaatat aggggaaaaa ccgtacgtat
    17701 tcttgggaaa agccgtacgc atttgttcga acaacatttt atcacccttt actctttctt
    17761 cactacaaat aactgtttta taatatgtta tagacggtga aaggtgaaat taaatttata
    17821 aaactccatt gggagattga ttttttcccc taaaaacgag aaggtgtgtc aaaacactat
    17881 taccgaacgc agacggagcg cagacaataa ttatttttta ataaaagttt gtgcctgtct
    17941 gcgtgttctg agtcgttagc gttcagtaat tactattttg acacatcacc caatcaattg
    18001 aattcttatt tctgagcctc cattcgcttc atattcgata atttccggtc attctccttt
    18061 actgatacga ttgttcagtt ctttcaacaa agcatacgat ttcggagaaa tcgttccatc
    18121 ctgataaatc cggacattaa tcatcggaag attttttcgt ttgttagatt ctttcactac
    18181 ctgcgtcaat tcgtcaatgg aaagaacagg atcaccgata atggaatctt tataaatgtg
    18241 cgtccagtca cccggctcca atgttccgga gaaagttgcc tgtaagccat cctgagggcc
    18301 accgtgaaac aatccgtccc catccaacgg aagagaagga tcgttaacac cggcactggc
    18361 caaagacaaa cccagttcgc cagcataata atcctgaaag tccgtcagtt tcggcaatat
    18421 ccaggaatta aaacaaatcg ccaactcctt atttccactt ttggcggctt tagcaatctt
    18481 ttcaaacgaa gcgccgttag gataataacc gataccgtca tccatccaca aaccggccag
    18541 acgatttcca taccgctggc taatctctcc cactatcttt tccacatttg taaacaaatc
    18601 tcctgcatta tcacgtgtat aatgctgctt gtcccaccat tctttatctc catgacnnnn
    18661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnccgtatt tacccaacgc atcagataaa
    18721 tcagccacta aatctctctt tgtggtacgc cccggcaaaa tagaatcgat tgcctgtatc
    18781 ggagccggga aataatattc cgcccacgac gttgtaaaaa atatcaactt cccgccacat
    18841 tcgtaaacag ttcgtgcaaa gcggtccaca tcaaagttat tgaccgcatc ctcataggct
    18901 aacggctctc ctgactgagg catactcttt gaattccagt ggaagaaaaa gccataaggc
    18961 aaatccgcca tccaggatgt attactgcga agtgatgtag cttccgcccg cagctgctca
    19021 taagtctccg gccgggtgac ttccaacgag tacagataca cattaaaatc atcctgctta
    19081 ccgggtttgc caatctttaa agataaaacg gaagtcccct tattaaaatg taaaggacgg
    19141 gggaaccggc aacgctgcca tccggttgta tttatccggc aaataacact gtccgttcca
    19201 ttggataata ccaactccgt ttcttcccca tctcccatcc ggttgacaga aacgatcatt
    19261 tcagccatgt agtcttcacc gtccgtattg actttccagg atattgactg ctcgggagtt
    19321 ttccagttct ccgcccagaa tgctttataa ggttcttccg gataaagttg tttcacacca
    19381 ttattcagtt ctccacgaaa aggaatcaac cggtttatgt tcgccgaatc caggtttaat
    19441 gccgtcggat caaccggatt actgcaagcg gccagacaca taacaaacaa agacaaaaaa
    19501 taaataaatt gctttttcat tcgtatttta cggatatagg aagggccaat caataataac
    19561 tcagaccggc ccttcatgta ttctacatta attatctgta atccggattc tgaggtatgt
    19621 tgttattcag aatttcggta tcaggaatca accaagtatt gttgtaagca ccgatgggga
    19681 cattcaatct gctgccacgc gctttctgta ccttatcgaa tgtctgggta cgtttcaaat
    19741 cgtaccaggc aaaaccctct tcatacaatt catgctgacg ttccagcaga acggcttcac
    19801 ggaactggtc ctgagaaagt ccgctcaagt caggcacgtt tgtcgggtcg ttctggtcga
    19861 cacgggcacg tttacggata gcattgatat attgataagc accggccggt ccgtttatct
    19921 cattttcagc ttcggcggca atcagataca tttcagccaa acgaatcaat tgagtctgcc
    19981 aggtcaaaat attggtatta gatgctggca actcctgttc cagatactct tcattgatat
    20041 acttattata atatgtacgc gcgatgactt tatttccttt cgcatttaca tattcaggtt
    20101 taattcccca ttctttacgc atatcacctt tatcgaagct ggcgataaaa gcatctgtcg
    20161 gaagatacaa ggctgtctgg ctgccaatcg gtgaagattc attatgcata ccgctatagc
    20221 tatcgggagc ggaaaacaac tgagcccaga tagtttcagc cgtataacgt tccgtcttaa
    20281 agactttatc gaaggtaggc atcaaagaat actgaccgct gttgattact tcaagcgctt
    20341 tctctttggc tttcgcataa ttttctttct gattcatcgg gaagccggct gatgtcagat
    20401 agatacgtgc cataatcgct tttacgaccc atttatttac acgtcccata tcctgcgctt
    20461 cttccggaag tttttgttcc gcatccagaa tatcgtcaaa aataaactga tagatatcag
    20521 cctgcggcgt acggtctatt gccacgtcgg catcactggt cacgacttta tcccgcaaag
    20581 ggacatctcc aaagaactgg accaatgtaa aataagacca ggcacgcaaa catttcgcct
    20641 caccgataat acgattcttg gtttcggcag taaaatcctt atcttctatc gactccaata
    20701 tcatattcgc attctttatc gtactgtatg ggccggacca ggcatttcta aaggcataaa
    20761 aaccatatcc cggattattt gcccagatat ccccgacctg ttcagccgat tcaggcttat
    20821 cattatagtc ggcaaaaact tccgtcagat tcagattttg tccctgagga tataaccctt
    20881 tcaaagctcc gtcaaaatct tccaccgttt gatagaagga agagggagaa ataaatgttt
    20941 tcgggtcttc ttccagccaa tcggagcaag aagcagacag aataaccggt acagccagca
    21001 atatattttt aatcagtgtt ttcattcttt tcatacgtat taaaatttaa cctgtaaacc
    21061 caaagtaaat gatttcgcag acgggtaaac ccctctgtcc catccgttca cggcagaaga
    21121 cgtccaggat gcttccgggt cataatgaga atagcttgta atcgtaatca gattctgtcc
    21181 gctcagataa accgagatat taggtttacg ggaacccgcg aaccattgag acggcaacgt
    21241 ataagccagt ttgatatctt tgaatcgcag atacgaaccg ttttccaccc aaaccgaact
    21301 cgggtcaccg aaggccagat aatccttggt cgcaacagaa gcacgtgcat atttggcatt
    21361 cggattttca ggagtccaat ggttttccca gacatctttg cggatattcc atgtgccacc
    21421 gatattagtg atacttttat taaattcatt aacgatatca ccaccaacac tacctattaa
    21481 caggaatgat aactcgaagt tattccaatt gataatattc gtcagaccga aagtaaactt
    21541 aggctgcgta tttgcaataa tcgttttatc acctgttgta ataccagctt tcccgtccgt
    21601 gtctttatac cggtaatcac ctgctttctt ggttgcttcg ccattcaaac gagcttcttc
    21661 atccgtctga taaatacctt ctatttcgta gccatacaat tggaacggag ctttaccgac
    21721 aaacagaggg aaccagtttc cgccaccgat aggagcatct atccgctgaa tcttatttcc
    21781 atacacatcc gaacccaaat ctttcacgat tgatctattg gatgtaatat tcaaattagt
    21841 cgtccagttc acttttcctt tcatattgat tgtattgata gatatttcaa aacctttatt
    21901 atcaatacgt cctaagtttc tcagcataga agaatatccg gaagacgggg gaagagtcgc
    21961 attatacagc aaatcgcgcg tttgtttcca ataatagtca aaaccgatat tcaggcggtt
    22021 ggaaaagaat ccgaagtcga cacctatatc cgtttgtgta gttgtttccc atttcaagtc
    22081 gtcgtttgcc atggaggata aaccgaaacc aatatctttt ccatcaccga aaataggacc
    22141 ggaagttccc agacgggcga aagtctgata cgggctaata gattgattac cggtctgtcc
    22201 gatactggca cgcagtttca gattgctcag ccaatcaata tcttgcataa aattctcttc
    22261 cgacaaacgc caggccaatg cggcggaagg gaagaaagcg aatttatggt tcttactgaa
    22321 tttagacgaa ccgtcatatc gtgcggtgac agtcaacaga tatctttcca tcaggttata
    22381 attggcacgt cccaggaaag aagccatccg gtaatcgctg taaccggaag acggagttcc
    22441 gggtgtagaa gctactccca aattattcgt ttcatagaca tcgcgcagaa atcctgtacc
    22501 tgagccgccc aaatcattat actgataggt ctggaaagta acaccaccca tcaggttcaa
    22561 tgcatgattc ttattgaacc gcttgtcgta ggtcaaaata ttctcattaa taatagtata
    22621 ataattagat tttgacttag acgcatcacc atccaattta cctccggcag acaaaccaat
//
