Select genomic region:
Overview
5.1
10.1
13.1
14.1
15.1
44.1

### Identified primary metabolite regions

c00005_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_5)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 5.1 | Putrescine2spermidine | Aliphatic_amine | 5,328 | 29,570 | Arginine2putrescine R. gnavus | PUTR | 100%

c00010_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_10)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 10.1 | Pyruvate2acetate-formate | SCFA | 52,427 | 67,166 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%

c00013_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_13)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 13.1 | acetate2butyrate | SCFA | 21,246 | 47,489 | Acetate to butyrate C. sporogenes | BUT | 100%

c00014_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_14)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 14.1 | Rnf_complex | E-MGC | 26,377 | 51,354 | Rnf complex C. sporogenes | RNF | 83%

c00015_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_15)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 15.1 | Others_HGD_unassigned | Putative | 1 | 22,434 |

c00044_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_44)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 44.1 | TPP_AA_metabolism | Putative | 1 | 13,208 | Threonine to propionate E. coli | PROP | 20%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 5.1 | Putrescine2spermidine | Aliphatic_amine | 5,328 | 29,570 | Arginine2putrescine R. gnavus | PUTR | 100%
Region 10.1 | Pyruvate2acetate-formate | SCFA | 52,427 | 67,166 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 13.1 | acetate2butyrate | SCFA | 21,246 | 47,489 | Acetate to butyrate C. sporogenes | BUT | 100%
Region 14.1 | Rnf_complex | E-MGC | 26,377 | 51,354 | Rnf complex C. sporogenes | RNF | 83%
Region 15.1 | Others_HGD_unassigned | Putative | 1 | 22,434 |
Region 44.1 | TPP_AA_metabolism | Putative | 1 | 13,208 | Threonine to propionate E. coli | PROP | 20%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_4)
  c00006_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_9)
  c00011_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_12)
  c00016_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_43)
  c00045_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|LNFEIKGE_60)

Compact view
c00005_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 5,328 - 29,570 nt. (total: 24,243 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00010_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 52,427 - 67,166 nt. (total: 14,740 nt) Show pHMM detection rules used
Region on contig edge.
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00013_gnlPro.. - Region 1 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 21,246 - 47,489 nt. (total: 26,244 nt) Show pHMM detection rules used
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00014_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 26,377 - 51,354 nt. (total: 24,978 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00015_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 22,434 nt. (total: 22,434 nt) Show pHMM detection rules used
Region on contig edge.
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00044_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 13,208 nt. (total: 13,208 nt) Show pHMM detection rules used
Region on contig edge.
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.