LOCUS       c00003_gnlPro..        15452 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NBGLNEMP_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:37:47
            Original ID  :: gnl|Prokka|NBGLNEMP_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15452
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..126
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="WNDELRSALCSLALLIPYYYILWLNKSRMGKKFSFSVRPMN"
     protocluster    1..15452
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[163:5452]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      164..5452
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15452
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15452
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             164..1120
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.5; E-value:
                     9e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_2"
                     /sec_met_domain="Fer4_7 (E-value: 2.5e-12, bitscore: 38.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-09, bitscore: 27.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.9e-08, bitscore: 25.7,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2e-08, bitscore: 25.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 4.3e-11, bitscore: 33.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-05, bitscore: 16.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRIYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALXXXXXXXXXXXXX
                     XXXXXNFPPRKPKADDAAPQVKVAAPKAEVETPKAEV"
     CDS             1181..2518
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="Fer4_10 (E-value: 8.2e-09, bitscore: 27.1,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.4e-15, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.9e-49, bitscore:
                     158.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.7e-29, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00013, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVAAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPIAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             2525..3517
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 7.4e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             3514..4179
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="FMN_bind (E-value: 8.7e-24, bitscore:
                     75.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLESSLKNMLLVLTGVTAISVALLAYVNELTKEPIAQANAKTL
                     SDAVSAVVPGFDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVL
                     VGFDAEGKIIDYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVD
                     AITASTITSRAFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             4214..4780
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.5e-70, bitscore:
                     227.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISAIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPALYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPVASLFDGLGMGLGFTIALTLLGAVREFLGTGKIFNLSILPEEYGML
                     VFVLAPGAFIALGYLIALINSMKKN"
     CDS             4868..5452
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.9e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             5584..6618
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.6e-53, bitscore:
                     173.6, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKILVTGGTGYIGSHTVVELQNAGYEVVIIDNLSNSSADVVDN
                     IEKVSGIRPAFEELDCLDYAGLDAVFTKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEIV
                     RDTVASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVVAIHRILENKQKEKVEVFNIGTGRGLSVLELINA
                     FEKATGVKLNYQIVGRRAGDIEKVWANPELANNELGWKAETSIEDTLLSAWKWQLKLRE
                     RGIQ"
     CDS             7229..8764
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MSQIVGHISQVIGPVVDVYFEGTEAEMMLPSIHDALEIKRSNGKR
                     LIVEVQQHIGENTVRTVAMDSTDGLQRGMTVHPLGGPITMPIGTQIKGRLMNVVGDSID
                     GMKELDRTGAYPIHRDPPKFEDLTTVQEVLYTGIKVIDLLEPYSKGGKIGLFGGAGVGK
                     TVLIQELINNIAKKQHGFSVFAGVGERTREGNDLLREMIESGVIRYGEEFKKGMEEGHW
                     DLSKVDYDEVAKSQVSLIFGQMNEPPGARQSVALSGLTVAESFRDMGAETDGPRDILFF
                     IDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTRNGSITSVQAVYVP
                     ADDLTDPAPATTFTHLDATTVLSRKITELGIYPAVDPLESTSRILDPHIVGVEHYEVAQ
                     RVKQILQRNKELQDIISILGMEELSDADRTLVNRARRVQRFLSQPFAVAEQFTGVPGTM
                     VSIEDTIKGFKMILDGEVDYLPEPAFLNVGTIEEAIEKGKKLLEQAGGKTIKN"
     CDS             8781..9032
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MMKKLHLNIVSPEKELFNGEVESVTLPGTMGSFSILPQHAPIVSS
                     LGTGKLIYATDGEEHELDIQSGFVEMSNGRVAVCIEQQ"
     CDS             9074..9493
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="VTITKRNYLLHTALLTVLIGIVGGWAYFSINPHHYFGGYPLIPLF
                     FFVFGVFMINMTESCRHRMPGRMLQIYLLMRVMRMLVSMIVMLVYCVAVREEARAFLLT
                     FIANYLIYLIYDSWFFFTFEANRKLKKKSNNEKIA"
     CDS             9477..10547
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="MKRLRNILTVILLALGMLLPATVRAENTVDVKEIVFGHIGDSYEW
                     HITTWGETHVTIPLPVIVHSSTTGWHAFLSSRLEENGGSYEGFSIAPAGSKYEGKLVEY
                     DATGNEIRPLDISITKVTLALLINSALLLLIILSVAHWYRKHPQGSAAPGGFIGFMEMF
                     IMMVNDDIIKSCVGPKYRKFAPYLLTAFFFIFINNIMGLIPFFPGGANVTGNIAITMVL
                     AICTFLAVNIFGTKTYWKDIFWPDVPWWLKVPVPMMPFIEFFGIFTKPFALMIRLFANM
                     LAGHMAMLVLTCLIFISASMGPALNGTLTVASVLFNIFMNALELLVAFIQAYVFTMLSA
                     VFIGLAQEEHKEKAVK"
     CDS             10604..10861
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="MLLSVLLQAAAAGVGVSKLGAAIGAGLAVIGAGVGIGKIGGSAME
                     AIARQPEASGDIRMNMIIAAALIEGVALLAVVVCLLVFFL"
     CDS             10957..11463
                     /locus_tag="ctg3_14"
                     /transl_table=11
                     /translation="MSLLLPDSGLLFWMLLSFGVVFVVLAKYGFPVITKMVEGRKTYID
                     QSLEVAREANAQLSKLKEESEALIAAANKEQGRILREAMHERDKIIVEARKQAEAAAQK
                     ELDEVKKQIQQEKEEAIRDIRRQVAVLSVDIAEKIIRKNLDEKHEQMEMIDRMLDEVLA
                     ASKNN"
     CDS             11475..12035
                     /locus_tag="ctg3_15"
                     /transl_table=11
                     /translation="MDIGIVSMRYAKALMEYAKSMGAEDTLYKEFCMLDRSFRKHPDLR
                     MALENPILTIREKLTLICTAAVGDAPAGREFARFMTLVLKNRRENFLQYICLSFLDLYR
                     KDKHIGVGKLITAVPVSQEVRERIHDSASSLLHASMELQTEVDPSIEGGFIFDINDFRL
                     DASIATQLKKVKQQFIDKNRRIV"
     CDS             12166..13752
                     /locus_tag="ctg3_16"
                     /transl_table=11
                     /translation="MLSENIKVSEVSDILRKQLEGIDTRVQLDEIGTVLQVSDGVARIY
                     GLRNAEANELLEFDNGIKAIVMNLEEDNVGAVLLGPTDKIKEGFIVKRTKRIASIMVGE
                     GMLGRVIDPLGAPLDGKGLIGGELYEMPLERKAPGVIFRQPVNQPLQTGLKAVDAMIPI
                     GRGQRELIIGDRQTGKTAIAIDTIINQRANFDAGDPVYCIYVAIGQKGSTVASIVNTLH
                     QYGAMDYTIVVAATAGDPAALQYYAPFAGAAIGEYFRDTGRHALVVYDDLSKQAVAYRE
                     VSLILRRPSGREAYPGDIFYLHSRLLERAAKIISQEEVAREMNDLPDSLKGKVKGGGSL
                     TALPIIETQAGDVSAYIPTNVISITDGQIFLDTNLFNQGNRPAIDVGISVSRVGGNAQV
                     KAMKKVAGTLKIDQAQYRELEAFTKFSGDMDPVTALTIDKGQKNTRLLVQPQYSPMPVE
                     KQIAILYCGTHGLLRNVPLDKVSEFERNFLESLEMNYRMEVLDVLKTGAINDDVCKKIE
                     ETAEAVARQFM"
     CDS             13874..14764
                     /locus_tag="ctg3_17"
                     /transl_table=11
                     /translation="MSSLKEVKNRISSVKSTRQITSAMKMVASAKLHKAQGRIENMLPY
                     QRKLNEILTNFLRTDASFESPYTEKRPVTRVAVVAFSSNSSLCGAFNSNVAKMLERALE
                     DYQSLGKENILIYPVGRKVEEAVKKMGYVPQGSYQVMADKPSYVEAYELAEKLMHEFVE
                     KQIDHVELIYHHFKSMGSQVLLRENYLPIDLTQVAQEAAEDVPEDARSFNNDYIVEPSV
                     GELIAELLPKVLSQKIFTVLLDSNTSEHAARMLAMQTATDNANELIQDLTKQYNKSRQQ
                     AITNELLDIIGGSLK"
ORIGIN
        1 tggaatgacg agctgcgttc tgcactttgt tcgctggcac ttcttatacc ttattattat
       61 atattgtggc tgaacaagtc gcggatgggt aagaagttct cattctccgt acgaccgatg
      121 aactaactaa taataaaaca aataattaat aaacaactaa tttatgaatg taattctgat
      181 tgcagtgatt tcattgggag ttatagcgct ggtatcggcc gctattcttt acgtggcttc
      241 caagaaattc gccgtgtatg aagatccgcg gattgcccag gtagcagagg tgcttcccca
      301 ggcaaattgc ggtggatgtg gttaccccgg ttgtagcgga tttgcagatg cttgcgtaaa
      361 ggcaggttcg ctggatggta aactttgtcc ggtgggtgga cagcccgtca tgacaaagat
      421 tgccgagatt ctgggcttgg atgccgctgc tgccgaacct atggttgcgg tggtgagatg
      481 taatggaact tgtgccaacc gtcctcgtgt gaaccaatac gatggcgcta agagttgtgc
      541 cattgcggct tctctctatg gtggtgaaac gggttgtagt tatggctgtc tgggatgcgg
      601 cgactgtgtg gctgcctgcc agttcgatgc tatccacatg aatccggaga ccggacttcc
      661 cgaagtggat gaggaaaagt gtacggcttg tggagcttgt gccaaggctt gtccgaaatc
      721 tattattgaa atccgtcctc aaggcaagaa atcacgtcgt atttacgtac agtgtgtaaa
      781 caaggacaag ggggccgtag cacgcaaggc ttgtaccgtg gcatgtatcg gttgcggcaa
      841 gtgtgtgaag gtttgtccgt tcgaggctat cacgctggaa aacaatctgg cttacattga
      901 ccccaataag tgtaaatcct gtcgcaagtg cgaggaagct tgtccgcaaa acacaatcat
      961 tgccctcnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1021 naacttcccg ccgcgcaaac cgaaggctga cgatgcagct ccccaagtaa aggttgcagc
     1081 tcctaaagct gaggttgaga ctcctaaagc agaggtttag acttcccaag ttgaggtatg
     1141 aattaataaa gtaaataaac gactaaaaat acagaattgt atgttgaaga cattttcaat
     1201 tggtggagtc catccacacg aaaataaact ttcagcacat cagcctatca tcaaggcaga
     1261 gattccggcc aaggccgcta tcttgctggg acagcacatc ggtgctcctg ccaagcctat
     1321 cgttgccaaa ggtgatgttg tgaaagtggg tacaaagatt gccgagcccg gcggttttgt
     1381 atcagcagcc attcattcgt ctgtcagcgg gaaagtcgct aagattgaca cgattgtcga
     1441 tgccagcggt tacgccaagc ctgctatatt cattgacgta gaaggggatg aatgggaaga
     1501 atccattgac cgttccgaaa cgttggtgaa ggaatgcagt ctgacctccg aggaaatcgt
     1561 gaagaaaatc gctgatgccg gtatcgtagg tctgggcggt gcatgcttcc ctacgcaggt
     1621 caagttgtgt cctcctcctg cattcaaggc agagtgtgtc atcatcaacg ccgtagagtg
     1681 cgaaccgtat ctgactgccg accatcagct gatgctggaa catgcggaag aaattatggt
     1741 aggtgtatcc attctgatga aggcggtaaa ggtgaacaag gcattcatcg gcattgagaa
     1801 caacaagccc gatgccatcc agctgatgac gaaggttgct tccagctatg caggtatcga
     1861 ggtggtaccc ttgaaggtac aatatccgca gggtggtgaa aagcagttga ttgatgctgt
     1921 catcagtcgc caggttgcag ccggtgcgct gcctatctcc acgggagctg tggtgcagaa
     1981 tgtgggtacc gcatttgccg tttaccaggc cgtacagaag aacaaacctc tgtttgaacg
     2041 tgtcattacc gtgaccggta agtctctggc aaagccgtcc aatttcctgg cacgtatcgg
     2101 tacgccgatg aagcagctga ttgaagcttg cggcggtctg cccgaagata cgggtaagat
     2161 tatcggcggt ggcccgatga tgggtaaagc tctggtaaat acggatgtac cgatagccaa
     2221 aggaagctcc ggtattctga ttatgaacga gaaggaagcc aagcgcggcg aagtacagcc
     2281 ttgtatccgt tgtgctaagt gcgtgggagc ctgcccgatg gggttggagc cgtatctgct
     2341 ggctaccgtt tcggcccacg gagattttga aagagtagag aaagaagaca ttatgtcgtg
     2401 tatagaatgc ggttcatgcc agttcacttg tccttccaac cgtccgatgc tggattatat
     2461 ccgcttgggt aagggtaagg taggagcgat gatccgtgca cgtcaagcta aaaaataacg
     2521 aagtatgaat aaattaatcg tatccctttc gccccacgtt cacggcggtg acagcgtgaa
     2581 gaagaatatg tacggtgtgc ttatcgcatt gattccggca ttcctcgttt cgctttactt
     2641 tttcggactg ggtgcgctga ttgttacggc cacttccgta gcagcctgct tgttctttga
     2701 atgggccatc ggcaaattcc tcatgaaaaa agagaccaca accatcaccg acggctctgc
     2761 catcattacc ggtgtgttgc tggcctttaa cctgccttcc aacctgccca tctggattat
     2821 catccttggt gccttgtttg ccatcggggt aggcaagatg tccttcggag gtttgggttg
     2881 caatcccttt aaccctgcac tggcaggacg tgtgttcctg ttgctttcat tccccgtgca
     2941 gatgacgaca tggccggctg taggccagtt gacagcctat acggatgcca cgacggctgc
     3001 tacgccgctg gctattatga aaggtgtcat caatggtgct ccgggcatgt ccctgagcga
     3061 ccttccggga gctttcgacc tgctgatagg taataatgga ggatgtctcg gtgaggtgag
     3121 tgctttggcg ctgctgcttg gtttgttcta catgttgtgg aagaaaatca tcacctggca
     3181 cattccggta tctattctgg tgacggtatt cgtgttctcc ggtatcatgt atctggtcaa
     3241 tccggaactt tatgtatccc cggtcgtaca gttgttgtcc ggtggtctga tgctgggtgc
     3301 tgtctttatg gctacggact acgtgacttc tccgatgagc cacaaaggta tgctgattta
     3361 tggtgtttgc atcggcctac tgactgtcat catccgtctg ttcggtgcat atccggaggg
     3421 tatgtcgttt gccattctga ttatgaatgc gttcactccg ctcatcaaca cctatgttaa
     3481 acctaaacgc tttggggagg tagcgaagaa gaaatgaaaa agttagaatc atccttgaag
     3541 aatatgttgc tggtacttac gggcgttacc gcaatctccg tagcgttgct ggcttatgta
     3601 aacgaattga cgaaggagcc cattgcgcag gccaatgcaa agaccttgag cgatgccgta
     3661 agtgcggtgg ttccgggctt cgacaatgac cccatcgccg agaagaagat gcaggaagta
     3721 aacggagtac agtattctgt atatcctgcc accaaaggcg gagaatatat cggagctgct
     3781 gtggaagctg ttgccatggg ttttggcggt gagctgaaag tgttggtcgg tttcgatgct
     3841 gaaggcaaaa tcatcgacta ctccttgttg tcgcatgtgg aaactccggg gttgggttcc
     3901 aaggctgccg actggttcaa gaaaggcaat aaaggtgaca tcaccggcat gaatccgggt
     3961 gaagctgcat tgacagtgag caaggacggt ggtaaagtag atgccattac agcgtctacc
     4021 atcacctcac gtgctttttt gaatgcagtg aatgcggctt atgctgccta tgccggtcag
     4081 gaaactgccg acggcactac cggcgctact caaaagaatg ttgaacaacc tgctgattcc
     4141 gcagctcccg aagctgtgga tacactcagc gctaaatgag aaaggagtag aagatatgaa
     4201 taattttaaa gttatgatga acgggattat caaagagaat cctacgtttg tactcctgct
     4261 gggtatgtgt cctacactgg gtaccacttc ctctgccatt aacggtatgg gtatgggact
     4321 ggctacaatg ttcgtgctga tatgttccaa tgtggtgatt tctgccatca agaatctgat
     4381 tcccgatatg gtgcgtatcc cttcattcat tgtagtcata gcatcatttg tgacactgtt
     4441 gcagatgata atgcaagctt acgttcctgc attgtacgcc acactgggcc tgttcattcc
     4501 gctgattgtt gtaaactgta tcgtattggg acgtgccgag gcatttgctg ccaaaaacaa
     4561 tccggtggct tccttgttcg acggtctggg catgggcttg ggctttacca ttgcactgac
     4621 attactgggt gccgtgcgtg agttcctggg aaccggcaag atattcaact tgagtatcct
     4681 tcctgaagaa tacggcatgt tggtatttgt ccttgctccg ggtgcattca tcgcattggg
     4741 ctatctcatt gctttaatca acagtatgaa gaagaattaa taatgaaaaa ttaaaaatga
     4801 aaaaattgag aacgtatcgg cggtaagctg ccgggctttt aatttttagt ttttaattct
     4861 taatttaatg attatggaat atatattgat atttatctcg gcaatctttg taaacaacat
     4921 cgtattgtcg caattcttgg gaatttgccc gttcttgggg gtttccaaga aagtggagac
     4981 tgcattgggc atgtcggcag cggtggcatt cgtgctcacc atcgccacta tcgtgacatt
     5041 ccttattcag aagtatgtgc tcgacgcttt tgatttgggc tatttgcaga ctattacctt
     5101 tatcttggtg attgccgcat tggtgcagat ggtagagatt atcctgaaga aagtttctcc
     5161 ttctctgtat caggccttgg gcgtgttcct gccgttgatt actaccaact gctgtattct
     5221 cggtgtggct atccttgtta tccaaaaaga ttatgatttg ctgacgggag tggtttatgc
     5281 attctccacg gcacttggtt tcggcttggc actgacactg tttgcaggcc tgcgcgagca
     5341 aatgagcctg gttagtgtac cgaaaggtat gcagggtact ccgatagctt tgattactgc
     5401 cggactgctg gcaatggcat tcatgggctt ttcgggggtt gtgaagattt aaagaagaaa
     5461 aaacggaaat aaagtggaag ggggataaac taaaatttat cccccttttt ctgtttttat
     5521 taatttattt ccttacattt gtggcgtatt gataacctaa aagctaaatt atctatattt
     5581 aatatgaaag ggaaaatctt agttacgggt ggaaccggtt atattggttc tcacacggtg
     5641 gtggaacttc aaaacgcagg ttatgaagtt gttattattg ataatttgtc aaactccagc
     5701 gcagatgttg tagataacat agagaaggta tcgggcatcc gccctgcatt cgaggaattg
     5761 gattgcttgg attatgccgg tcttgacgct gtgtttacca aatataaagg cattaaagcc
     5821 atcattcact ttgcggccag caaggctgtg ggtgaatctg tccagaaacc attgctttac
     5881 tatcgtaata acctggtttc actgataaac ctgctggaat tgatgccgaa gcatggagtg
     5941 gaaggtatcg tattctcttc ttcctgcaca gtttacggcc agccggacga acttccggta
     6001 acggaaaagg cacctattaa gaaagctgag tctccgtatg gaaacacgaa gcaaatcaat
     6061 gaagagattg tacgtgatac ggttgcttcc ggtgctccga taaacgccat cttgttgcgt
     6121 tacttcaacc cgataggtgc acaccccaca gcattgctgg gagagttgcc taacggtgta
     6181 ccgcagaact tgattcctta tcttacccag accgctatcg gcatccgtga gaaactgagc
     6241 gtgtttggtg acgattatga tactcccgac ggttcttgta tccgcgactt catcaatgta
     6301 gtcgatttgg ccaaagcaca cgtagtggct atccaccgta tcttggagaa caagcagaag
     6361 gaaaaagtgg aagtattcaa tatcggtaca ggtcgtggac tttccgtatt ggaactgatt
     6421 aatgctttcg aaaaggctac cggtgtaaaa ctgaactatc agatagtagg tcggcgtgcc
     6481 ggtgatattg agaaggtatg ggcaaacccg gaattggcaa acaatgaact gggttggaag
     6541 gcagaaacaa gtattgaaga tactttactt tctgcatgga aatggcagtt gaagcttcgt
     6601 gaaagaggta ttcaatgaca aactttgaat ttgtgttttt taacaaatag gcaataaaca
     6661 aatgcctccc cgcatttgtt tataatgtgc aaatcagcct gaagctgttt atgtatatgt
     6721 gaatatccgt aactagtacg tatgcctccc cggcatagac aggtaagatt gcatagtagt
     6781 tttgtcgtgt tttattttgt gtttgtgttg tgaataagcc ttgtcgagag acaaggctta
     6841 ttttttgtat attatataca gaatctctgt tgtcaattca gtgttttttc ataagatggg
     6901 tgggcaattc ctttttcttg ctaattgtta actgacgtta tcatgtctgt aacaatttgt
     6961 tccaattgta gtattaatcg ttcaaaatag tcttttttgt tcaaaaaatg ctatacacgg
     7021 taacaactac atgcaaattg tttatacatt tgcgttgttg tttatgtaac tattgggatg
     7081 aacaaaccat agctgacaaa cgttaatagg tacgagtaca tagctgatga aagacgcgac
     7141 ttggctgact tgttaatgag gatacacgcg acttacaact tagtattggg aaaaataatt
     7201 aaggaaatat agaataaaaa gattgcttat gtcacagatt gtcggacata tctcacaggt
     7261 aatcgggcct gtagtagacg tctatttcga aggaacggag gcagaaatga tgttgccgag
     7321 tattcacgac gcactggaaa taaaaaggtc gaacggcaaa agactgattg tagaggtaca
     7381 gcagcacatt ggtgaaaaca cggtgcgtac tgttgctatg gacagtacgg acggcctgca
     7441 gagaggaatg acagtgcatc cgctgggagg ccccatcacc atgccgatag gtacacaaat
     7501 caaaggccgc ctgatgaacg tagtgggcga ctctatcgac ggcatgaagg agttggaccg
     7561 tacaggtgct tatcccatcc atcgcgaccc ccctaagttt gaagatttga ctaccgtaca
     7621 agaggtgctt tatacaggca tcaaggttat cgacttgctg gaaccatata gcaagggcgg
     7681 taaaatcggt ctgtttggtg gcgccggtgt aggcaagacg gtgcttatcc aagagctcat
     7741 taacaatatt gcgaagaagc agcacggctt ctctgtgttt gccggtgtag gagaacgtac
     7801 acgtgaaggc aacgacctgc tgagagaaat gattgaatcc ggcgttatcc gttacggaga
     7861 agaattcaag aaaggtatgg aggaaggcca ttgggatttg tccaaagtag attatgacga
     7921 agtggccaaa tcacaagtgt ctttgatatt cggtcagatg aacgaacctc ccggtgcgcg
     7981 tcagtccgtg gcattgtctg ggttgacggt ggccgagtcc ttccgtgaca tgggagcgga
     8041 gacggacggt ccgcgtgaca ttctgttctt cattgataat atcttccgtt tcacccaagc
     8101 cggttccgag gtttcggcct tgctgggccg tatgccttct gccgtaggct atcagccgac
     8161 actggcaacg gaaatgggtg ccatgcagga gcgtattacc tctacaagaa acggctccat
     8221 cacttccgtg caggctgtat atgtgcctgc cgatgacttg acggacccgg cacctgccac
     8281 aacgtttacc cacctcgatg ccaccacggt gttgagtcgt aagattactg aacttggtat
     8341 ttatcctgct gtggacccgt tggaatctac ttcacgcatt ctcgacccac acatcgtggg
     8401 ggtagaacac tacgaagtgg cacaacgtgt aaaacaaata ttgcagcgca acaaggaatt
     8461 gcaagacatt atctccatcc ttggtatgga ggaactctct gatgccgacc gtacgttggt
     8521 gaaccgtgca cgtcgtgtgc agcgtttcct ttcacagccg tttgccgttg ccgagcagtt
     8581 tacgggtgtc ccaggtacaa tggtttccat tgaggacact atcaaaggct tcaagatgat
     8641 tcttgacggg gaggtggact acctgcccga acctgctttc ttgaatgtgg gaaccattga
     8701 agaagccatt gagaagggta agaaactact ggagcaggca gggggaaaaa cgattaaaaa
     8761 ttaaaagtct gggagctttg atgatgaaaa agttgcattt gaatattgtt tcaccggaga
     8821 aggaactctt caacggggaa gtggaaagtg ttacattgcc gggcactatg ggctcttttt
     8881 ctatcctgcc gcagcatgca ccgattgtat catcgttggg aacggggaaa ttgatttacg
     8941 caacggacgg tgaggaacat gagttggata ttcaaagcgg attcgtggag atgagtaacg
     9001 gaagggttgc cgtctgtata gaacagcaat aggctattaa aaaattaaaa attaaaaaat
     9061 agaggttgtt ggcgtgacta ttactaagag aaactactta ttgcatacag cgctcttgac
     9121 ggtattgata ggaattgtag gcggttgggc gtatttttcg ataaatccgc atcactattt
     9181 cggcggttat ccgctgattc cgcttttctt ctttgttttc ggagtattca tgattaatat
     9241 gaccgaaagc tgccgtcacc ggatgccggg acgaatgttg cagatttatc tgctgatgcg
     9301 tgtgatgaga atgctggtct ccatgattgt gatgctggtt tattgcgttg cagtacgtga
     9361 ggaagccagg gcgtttctgt tgacgtttat agccaactat ctgatatatt tgatttatga
     9421 ttcctggttc ttcttcactt ttgaggcgaa tcggaaactg aaaaagaaaa gtaacaatga
     9481 aaagattgcg taacatactg actgtaattc tgctggcact gggcatgttg ctacccgcca
     9541 cggtgcgggc cgagaatacg gtggacgtga aggagattgt cttcgggcat atcggcgatt
     9601 cttacgaatg gcacatcacg acgtggggcg aaactcacgt tacgattcct ttgccggtaa
     9661 tagtgcatag ctctaccacc ggatggcatg cctttctatc ctcacgtctg gaggagaacg
     9721 gtggaagtta tgaaggcttt tccatcgctc ccgcaggaag caagtacgaa ggcaagctgg
     9781 tggagtatga tgccaccgga aacgaaatac gcccgttgga catctccatc acgaaggtga
     9841 cactggcttt gctcatcaac agcgcattgc tgcttctcat cattttgagt gtggcgcact
     9901 ggtatcgcaa gcacccgcag ggaagtgccg ctcccggtgg tttcatcggg tttatggaga
     9961 tgtttatcat gatggtgaac gatgatatta taaagagctg tgtcggtccg aagtaccgta
    10021 aattcgcacc ttacttgctg acggccttct tctttatttt catcaacaac attatggggc
    10081 tgattccttt ctttcccgga ggggccaacg tgacgggaaa tatagccatt acgatggtat
    10141 tggccatctg tactttcttg gccgtgaata tctttggaac caagacttat tggaaagata
    10201 tcttttggcc ggatgtgccc tggtggctga aggtaccggt ccccatgatg ccgtttatcg
    10261 agttcttcgg tattttcacc aaaccgtttg ctttgatgat acgtcttttt gccaatatgc
    10321 tggcagggca catggcaatg ctggtgctta cctgcctgat attcatctcg gccagtatgg
    10381 gacctgcttt gaacggaacg ctgaccgtgg catcggtgtt gttcaatatc tttatgaatg
    10441 cacttgagtt gttggttgcc tttatccagg catatgtgtt caccatgctg tcagccgtgt
    10501 tcatcggtct ggcgcaggaa gagcataagg agaaggcggt gaagtgatac gattattggg
    10561 aatataaata ttaataaaaa taaccattta aaaactgaaa gttatgttac tatctgtatt
    10621 attgcaagct gctgcggcag gtgtgggagt tagtaaactg ggtgcagcca ttggtgctgg
    10681 tttggctgtt attggtgctg gtgtaggtat tggtaaaatc ggcggttctg ctatggaggc
    10741 cattgcccgc cagccggaag catccggaga tatccgtatg aacatgatta ttgccgctgc
    10801 cttgattgaa ggtgttgctt tgttggcagt agttgtgtgt ttattggtat tctttttata
    10861 atgtacaatc taccatttac catttacaat ttgtccgtgc agcatcaccg cgcagccaaa
    10921 ttgtaaatcg taaattgtca aatagtaaat aaaattatgt cattgttatt acccgatagt
    10981 ggtctgctgt tctggatgct cctttcattc ggtgtggtgt ttgtggtgct tgccaagtac
    11041 ggttttcccg ttatcaccaa gatggtggaa ggtcgcaaga cctacatcga ccagtctttg
    11101 gaagtggcac gcgaagcaaa tgcccagctc tccaaactga aagaggagag tgaagcgttg
    11161 attgctgctg ccaacaaaga acaaggacgt attctgcggg aggcgatgca tgagcgtgac
    11221 aagattatcg tcgaagcacg caagcaggcg gaagccgccg cgcagaagga gctggacgaa
    11281 gttaaaaagc agatacagca agagaaggaa gaggccatcc gcgatattcg ccgccaggtg
    11341 gcagtcttgt ccgtagatat agccgagaaa attatccgca agaatctgga cgagaaacat
    11401 gagcagatgg agatgataga ccggatgctg gatgaagtgc tggccgcaag taaaaacaat
    11461 taattctcaa agaaatggat ataggaatcg tttcgatgcg ttatgcgaaa gcattgatgg
    11521 aatatgccaa gagcatgggg gcagaagata ctctgtacaa ggagttttgt atgctcgacc
    11581 gtagcttcag gaaacatccg gatttgcgca tggcattgga aaaccccatc ctgacgatac
    11641 gtgagaagtt aacacttatc tgtaccgctg ctgtggggga tgctcctgcg ggccgtgagt
    11701 ttgcgcgttt catgaccctg gtgttgaaga accggcggga aaactttctc cagtacatct
    11761 gcctgagttt tctggatttg taccggaaag acaagcatat cggtgtagga aagctgataa
    11821 cagccgttcc cgtcagtcag gaagtgcggg agcgcatcca tgacagtgct tcctccctgc
    11881 tgcatgccag catggagctg cagactgaag tggatccctc cattgaaggt ggttttatct
    11941 tcgacatcaa cgacttccgt ctggatgcca gtattgctac gcagcttaag aaagtgaaac
    12001 agcagttcat tgataagaat agaagaatcg tgtgatttac gatttgacaa tttacaattt
    12061 acttatttaa tagtcttgtg atgcgtaagt tgtagaggtc aaacagtata tgattcgggt
    12121 tctttcaaat agtaaatagt aaattgtaaa atagtaaata ctaagatgtt gtctgaaaat
    12181 ataaaagtaa gcgaagtctc cgatattctc cgcaagcaac tggaagggat tgacacccgc
    12241 gtacagttgg acgagattgg cacggtactg caagtcagtg acggtgtagc ccgtatctat
    12301 gggttgcgca atgccgaagc caacgagttg ttggagttcg acaacggcat caaggccatt
    12361 gtgatgaacc tcgaagagga taatgtgggt gctgtgttgc ttggccctac ggataaaatc
    12421 aaggaaggct tcattgtaaa gcgtaccaag cgtattgctt ccatcatggt gggagagggt
    12481 atgctgggcc gtgtaataga ccctctgggt gcgccgctcg atggcaaagg actgataggc
    12541 ggagaacttt atgaaatgcc gctggaacgc aaggcgccgg gagttatctt ccgtcagccg
    12601 gtgaatcagc cgctacagac cggtctgaag gctgtggatg ccatgatacc tatcggccgt
    12661 ggacagcgtg aactgattat cggtgaccgc cagaccggta agacggccat tgccatcgat
    12721 accatcatca accagcgtgc caattttgat gctggcgatc cggtatattg catttatgta
    12781 gccattggcc agaaaggttc taccgttgcc tctatcgtga ataccctgca ccagtacggt
    12841 gcgatggact ataccattgt ggtggctgct acggcgggag acccggctgc attgcagtat
    12901 tacgctccct ttgcaggggc tgccatcgga gagtatttcc gtgataccgg ccgtcatgcg
    12961 ctggtggtct atgacgactt gtccaagcag gcggtggcct atcgtgaagt gtctctgatt
    13021 ctgcgccgtc cgtcaggacg tgaggcctat ccgggtgata tcttctatct gcactcccgt
    13081 ttgttggaac gtgcggcgaa gattatcagc caggaggaag tggcacgcga gatgaacgac
    13141 ctgccggaca gtctgaaagg caaggtgaaa ggtggcggtt cgctgactgc attgcccatt
    13201 atcgaaactc aggcaggaga cgtgtccgcc tatatcccaa cgaatgtgat ttcaatcact
    13261 gacgggcaga tattccttga tacgaacctc ttcaaccagg gtaaccgtcc ggccattgac
    13321 gtgggtatct ctgtgagccg tgtgggtggt aatgcccaag tcaaggctat gaagaaggtg
    13381 gcaggtacat taaagattga ccaggcacag taccgggagc tggaagcgtt taccaagttc
    13441 agtggcgata tggaccccgt gacggcattg accatcgaca agggacagaa gaatacacgc
    13501 ctgctggtac agccccaata cagcccgatg ccggtagaaa agcagattgc cattctttat
    13561 tgcggcacgc acggcttgtt gaggaatgtt cctttggaca aggtcagcga gtttgaacgc
    13621 aacttccttg agtctcttga gatgaactat cgcatggagg tactcgacgt tttaaagacg
    13681 ggtgccatca atgacgatgt ctgcaagaag attgaggaga cggcagaggc ggttgcaagg
    13741 caattcatgt aatttacgat tggacgattt acgatttacg attggggcta ctctatatgg
    13801 taagtggtaa atcggctgca agcaaaagta acttcaatcg taaatcgtaa ataattaaat
    13861 cgtaaataga tatatgtctt cactgaaaga ggtaaaaaat agaataagct ccgtcaagag
    13921 tacacgccag ataacatcgg ctatgaagat ggtggcatct gccaaactgc ataaggcgca
    13981 ggggcggatt gagaatatgc tgccttatca acggaagctg aatgagattc tgacgaactt
    14041 tctgcgtacg gatgcttcct tcgagtcgcc ctataccgag aaaagacccg tgacgagagt
    14101 agcggttgtg gcgttttcgt ccaatagttc cttgtgcggt gcattcaact cgaatgtggc
    14161 gaagatgctg gaacgggctt tggaagatta ccagtcgctg ggcaaggaga atattctgat
    14221 atatcccgtt gggagaaagg tggaggaagc cgtcaagaaa atgggatatg tgccgcaagg
    14281 cagctaccag gtgatggcag acaagccttc gtacgttgaa gcgtatgagc tggcagagaa
    14341 gttgatgcat gagtttgtgg aaaagcagat tgaccatgtg gagttgattt accatcactt
    14401 caaatcgatg ggttcgcagg tgctgctccg cgagaattat ctgcccattg acctgacgca
    14461 agtagcgcag gaggcggcag aagatgtacc ggaggatgcc cgcagtttta ataatgatta
    14521 cattgtggaa ccttccgtcg gcgaactgat agcggaactt ctgccaaaag tgttgagtca
    14581 gaagatattt accgtgcttc tcgattccaa tacttcggaa catgctgccc gtatgcttgc
    14641 catgcagacg gcgacagata atgccaacga gttgattcaa gatttgacga aacagtataa
    14701 caagagccgt cagcaggcca ttacgaatga gctgctcgat attatcggcg gtagcttgaa
    14761 atagtccgga ttgccccgta aagggctttc tcaggatggg tacaaataaa tggaataata
    14821 ggacaaggat aacgaaataa ccgctatctt tgtcctatta tcatatatgg ctactgatga
    14881 aatccgtatc attctgagag agagcggatt ggttgaataa taaacatatc aatggagaat
    14941 aatcccgaaa tagcgcttgc atggcaattc attgaaaaca caggcactca tctttttttg
    15001 accggcaagg caggtaccgg taagacaact ttcctgcgaa aactgagggc agagagtccg
    15061 aaacggatga ttgtacttgc accgacggga attgccgcta tcaatgcagg cggtgtcacc
    15121 atccactcct ttttccaagt accttttgct ccttatgtgc ccgaaagctc attcagcgca
    15181 gatggcaagg caacctaccg ttttcgttac gggaaagaga aaatcaacat tatacgcagc
    15241 atagatttat tggtcatcga tgaaatcagt atggtccgtg ccgacttgct cgattcggtg
    15301 gatgccgtct tgaggcggtt ccgcgaccgg aacaaaccct ttggcggcgt gcaactgctg
    15361 atgattggcg acttacagca gctgtctccc gtagtgaaag acgatgagtg gcagatgctg
    15421 cgcaaatact atgacacgcc ttatttcttc tc
//
