LOCUS       c00174_gnlPro..         5054 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ANJMKACL_174.
ACCESSION   c00174_gnlPro..
VERSION     c00174_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:45:09
            Original ID  :: gnl|Prokka|ANJMKACL_174
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5054
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5054
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[646:4789]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      647..4789
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5054
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5054
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..608)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg174_1"
                     /sec_met_domain="IlvN (E-value: 7.9e-48, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKINFGGVEENVVTREEFPLEKALETLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFRVIVGQREGSASWDKAVADGWVPGQTLFGIEEAAERATIIQYLLSDAGQI
                     AVWPSIKKHLTPGKALYFSHGFGITYKERTGIVPPADVDVILIAPKGSGTSLRRMFLQG
                     RGLNSSYAVFQDATGRAFERVVALGIGVGSGYLFETDFK"
     CDS             complement(647..1198)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg174_2"
                     /sec_met_domain="ALS_ss_C (E-value: 9.8e-20, bitscore:
                     59.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQEYIITVFSENKVGLLSQITTVFTCRDVNIESLTTSESALQGI
                     HKFTIVVRTTPDQVDKLVRQVEKKIDVLKTFVYTPDEVVQQEIALYKVTRSRGVEQLVR
                     EHNVRILEIDEDYIVVEKTGHKADTQALFRLLQPYGVQQFVRSGTVAIIKSRRELLNEY
                     LEEIDRLRAESDEEGSKSEK"
     CDS             complement(1212..2948)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg174_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.7e-48, bitscore:
                     150.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSQTLRPEERRAASDPSMTGSKALIESFLQEGVETVFGYPGGA
                     IIPVYDALYDYRDRLRHILVRHEQGAVHAAQGYARVSGRVGVCLVTSGPGATNTVTGLA
                     DALMDSTPLVLVTGQVGSALLGTDAFQETNFIGITQAVTKWNCQVKRTEDIPAAIAKAF
                     YIARSGRPGPVVVDITKDAQCGTAPFRYEKITSIRSYLPAPVPDAERIAEAARLIDQAR
                     RPLVMVGQGVILGNAEAELRALLDKSGMPAASTLLGLPALPTDHPQNVGMLGMHGNYGP
                     NIKNQECDLLVAVGMRFDDRVTGNPAHFGANAKVIHLEIDPAEIGKIIPADVAVVGDVK
                     RSLPLITERIRKRDHSQWIAGFRACNQIEYEAVIRKAVHPAEGRIRMGETVAAVARAYR
                     NDAVLVTDVGQQQMNAARYFGFRRTRSVVTSGGLGTMGFGLPAAIGAKLGAPDREVVLF
                     AGDGGLQMTIQELGTIFQSKIPVKIVLLNNSFLGMVRQWQELFYDRRYSFTEMVNPDFG
                     LIARGNGLSYRCVERREELDEAIAAMKASEGAFLLEVRVEGEENIFPMVPAGAPVSEIR
                     FE"
     CDS             complement(2963..4789)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg174_4"
                     /sec_met_domain="ILVD_EDD (E-value: 6.1e-220, bitscore:
                     719.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHTLKSAVTTTGRRMAGARSLWRANGMREEQFGRPVIGIANSFT
                     QLVPGHVHLHEIGQYVKQRIEALGCFAAEFNTIAVDDGIAMGHDGMLYSLPSREIIADS
                     VEYMASAHKIDALVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGKFQGRGVDLID
                     AMVMGADETCSDAQIAEIERCACPGCGSCSGMFTANSMNCLTEALGLSLPGNGTIVATH
                     VNRRRLFEDAAALIVRNAERYYFEGDERVLPRSIATKSAFENAMSLDIAMGGSTNTVLH
                     LLAVAHEAGVDFTMQDIDRLSRRVPVLCKVAPNSHYHIQDVNRAGGIFAILGELDRAGL
                     LDTSVLRVDGRTLGEAIPACDILNPAAADAARRRALGAPAGHYSRELGAQHSYYEEPDT
                     DRTAGCIRDVEHAYFRDGGLAVLTGNIARQGCVVKTAGVDEKLFVFRGPARVYESQEQA
                     MNGILADEVQPGEVVVIRYEGPKGGPGMQEMLYPTSYLKSKHLDKACALITDGRFSGGT
                     SGLSIGHVSPEAASGGEIAVVRTGDEIEIDIPGRSIRLAVDDAEIAARMAAQERFRPAG
                     RDRRIPASLRAYARLVSSADKGAVRIVDDNEE"
     CDS             complement(4903..5052)
                     /locus_tag="ctg174_5"
                     /transl_table=11
                     /translation="QKASGITGRPGLHADALSQKTNKHGKPAMNALNHSNIHVITLLLV
                     VLRR"
ORIGIN
        1 cgcttgaagt cggtttcgaa caggtagccc gaacccacgc cgatgcccag cgccacgacg
       61 cgttcgaagg cgcggcccgt ggcgtcctgg aacaccgcat agctcgaatt gagtccgcgg
      121 ccctggagga acatgcgccg cagcgaggtt cccgagcctt tcggggcgat caggatcacg
      181 tccacgtcgg ccgggggcac gatgcccgtg cgctccttat aggtgatgcc gaagccgtgg
      241 gagaaataga gggccttgcc cggcgtgagg tgctttttga ttgaaggcca tacggcgatc
      301 tgcccggcgt cggagagcag gtactggatg atcgtggcgc gctcggcggc ctcctcgatg
      361 ccgaaaagcg tctggcccgg aacccagccg tcggctacgg ccttgtccca gctcgcggag
      421 ccttcgcgct ggcccacgat gaccctgaat ccgttgtcgc gcaggttgag cgactgtccg
      481 gggccttgca cgccgtagcc gatgacggcg atggtctcgt ccttgagtgt ttcgagcgct
      541 ttttccagag gaaattcctc gcgggttacg acgttctctt cgacgccgcc gaaattgatc
      601 tttgccatgg ttttcgtgat ttttagtttg ttatatgttc tgaaagttat ttttcgcttt
      661 tgctcccttc ttcatcggat tcggccctta aacggtcgat ttcttcaagg tactcgttca
      721 gcagctcgcg ccgcgacttg atgatggcca ccgtgccgct gcgcacgaac tgctgtacgc
      781 cgtagggttg cagcaggcgg aacaacgcct gcgtgtcggc cttgtggccg gttttctcga
      841 cgacgatgta gtcctcgtcg atctccagaa tgcggacgtt gtgttccctg acgagttgtt
      901 cgacgccccg gctgcgggtc accttgtaga gggcgatctc ctgctgcacg acctcgtcgg
      961 gggtgtagac gaaggtcttc agcacgtcga tcttcttctc gacctgccgc acgagtttgt
     1021 cgacctggtc gggtgtggtg cggaccacga tggtgaattt gtggatgccc tgcaacgccg
     1081 attccgaggt cgtgaggctc tcgatgttca cgtcgcggca ggtgaagacg gtggtgatct
     1141 ggctcagcag gcccaccttg ttctccgaaa acacggtgat gatgtattcc tgttccatac
     1201 gctgtttcgt tttattcgaa ccggatttcc gataccgggg cgcccgccgg gaccatcggg
     1261 aaaatgttct cttcgccctc gacgcgtacc tccagcagga aggcgccttc ggaggctttc
     1321 atggcggcga tggcctcgtc gagttcctcg cgccgttcga cgcagcggta cgaaaggccg
     1381 ttgccgcggg cgatcagccc gaaatcgggg ttgaccatct ccgtaaagga gtagcggcgg
     1441 tcgtagaaca gctcctgcca ttggcgcacc atgccgagga acgagttgtt cagcaggacg
     1501 attttcacgg ggatcttcga ctggaagatc gtgcccagct cctgaatggt catttgcagg
     1561 ccgccgtcgc cggcgaaaag gacgacttcg cggtcggggg cgcccagctt ggccccgatg
     1621 gccgccggaa gtccgaatcc catcgtgccg agaccgcccg aggtaaccac gctgcgcgtg
     1681 cggcggaatc cgaaatagcg cgcggcgttc atctgctgct ggcccacgtc ggtcaccagc
     1741 accgcgtcgt tgcggtaggc ccgggccacg gcggcgaccg tctcgcccat gcggatacgc
     1801 ccctcggcgg ggtgcacggc cttgcggatg acggcttcgt attcgatctg gttgcaggcg
     1861 cggaatccgg cgatccattg gctgtggtcg cgtttgcgga tacgctcggt gatgagcggc
     1921 agggagcgtt tcacatcgcc cacgaccgcc acgtcggccg ggatgatctt gccgatctcc
     1981 gcggggtcga tctccaggtg gatcaccttg gcgttggcgc cgaaatgcgc gggattcccc
     2041 gtcacgcggt cgtcgaaacg catgcccacg gccacgagca ggtcgcactc ctggttcttg
     2101 atgttgggac cgtagttgcc gtgcatgccc agcatgccca cgttttgcgg atggtcggtc
     2161 ggcagggccg ggagacccag cagggtcgag gcggcgggca tgccgctctt gtcgagcagc
     2221 gcccgcagct cggcttcggc gttgcccagg atgacgccct gacccaccat gaccagcgga
     2281 cggcgggcct ggtcgatcag ccgtgcggct tcggcgatgc gttccgcgtc ggggacgggc
     2341 gcggggaggt aactgcggat cgaggtgatt ttttcgtagc ggaacggagc tgttccgcat
     2401 tgtgcgtcct tggtgatgtc gaccacgacg ggacccggac ggcccgagcg ggcgatgtag
     2461 aaggccttgg cgatggccgc gggaatgtcc tcggtgcgct tgacctggca gttccatttg
     2521 gtgacggcct gcgtgatgcc gatgaaattg gtctcctgaa aggcgtcggt gcccagcagc
     2581 gcggagccga cctgtccggt gacgagcacc agcggcgtgg agtccatcag cgcgtcggcc
     2641 agccccgtca cggtgttcgt ggcgccggga cccgaggtca ccagacagac cccgacgcgg
     2701 ccgctgacgc gggcatagcc ctgtgcggcg tgcacggcgc cctgctcgtg acgtacgagg
     2761 atgtggcgca ggcggtcgcg gtagtcgtaa agcgcgtcgt agacggggat gatcgcgcct
     2821 ccgggatagc cgaaaacggt ttcgacgccc tcttggagaa atgattcgat cagggccttc
     2881 gatcccgtca tcgaggggtc ggaggccgcg cgtcgctctt cgggacggag tgtttgagag
     2941 gtattcattg cgggtccgtt ttttattctt cgttatcgtc gacgatacgt acggcgcctt
     3001 tgtcggccga gctgaccagc cgggcatagg cgcgcagcga cgccggaatg cggcggtcgc
     3061 ggccggcggg gcggaagcgt tcctgtgcgg ccatgcgggc ggcgatctcc gcgtcgtcga
     3121 ccgcgaggcg gatcgagcgg ccggggatgt cgatctcgat ctcatcgccc gtgcggacga
     3181 cggcgatctc tccgcccgag gcggcttccg gcgagacgtg gccgatcgaa agccccgagg
     3241 ttccgcccga gaaacgcccg tcggtgatca gcgcgcaggc cttgtcgagg tgtttcgact
     3301 tgaggtacga cgtggggtag agcatctcct gcatgcccgg gccgcccttg gggccttcgt
     3361 agcggatgac gaccacttcg cccggctgca cctcgtcggc gagaatgccg ttcatggcct
     3421 gctcctgcga ttcgtaaacg cgcgccgggc cgcggaagac gaacagtttt tcgtccacgc
     3481 cggcggtttt gacgacgcag ccctgccggg cgatgttgcc cgtcagcacg gccagtccgc
     3541 cgtcgcggaa ataggcgtgc tccacgtcgc ggatgcagcc cgccgtgcga tcggtgtcgg
     3601 gttcttcgta gtaggagtgc tgtgcgccca gctcgcggct gtaatggcct gccggggcgc
     3661 cgagcgcgcg gcgtcgcgcg gcgtcggcgg ctgccgggtt gagaatgtcg caggccggga
     3721 tcgcttcgcc cagcgtgcgc ccgtcgacgc gcaggaccga ggtgtcgagc agtccggcac
     3781 ggtcaagctc gcccagaatg gcgaagatgc ctccggcgcg gttgacgtcc tggatgtggt
     3841 agtgcgagtt gggggcgacc ttgcagagca ccgggacccg gcgcgaaagg cggtcgatgt
     3901 cctgcatcgt gaaatcgacg ccggcctcgt gggccacggc cagcaggtgc aggaccgtgt
     3961 tggtcgagcc gcccatggcg atgtctaacg acatggcgtt ttcgaaggcg gacttcgtgg
     4021 cgatcgaacg cggaagcacc cgctcgtcgc cctcgaagta gtaacgttcg gcattgcgga
     4081 cgatgagcgc cgcagcgtcc tcgaacagcc ggcggcgatt gacgtgggtg gcgacgatcg
     4141 tgccgttgcc cggcagcgag agacccagcg cctcggtcag acagttcatc gagttggccg
     4201 tgaacatgcc cgagcacgat ccgcagccgg ggcaggcgca gcgctcgatc tcggcgatct
     4261 gcgcgtcgct gcacgtctcg tcggccccca tcaccatggc gtcgatcagg tcgacgccgc
     4321 ggccctgaaa ttttccggcc tccatcggcc cgcccgagac gaagaccgtc gggatgttga
     4381 gccgcatggc ggccatcagc atgccggggg tgatcttgtc gcagttcgaa atgcagacca
     4441 gcgcgtcgat cttgtgggcg gaggccatgt actcgacgct gtcggcgatg atctcgcgcg
     4501 aaggcagcga gtagagcatg ccgtcgtggc ccatggcgat gccgtcgtcg acggcgatgg
     4561 tgttgaactc cgcggcgaag cacccgaggg cttcgatgcg ctgtttgaca tattgtccga
     4621 tttcgtgcag gtgtacgtgc cccggcacga gttgggtgaa cgaattggcg atgccgatga
     4681 ccggccggcc gaactgttct tcgcgcatgc cgttggcgcg ccagaggctt ctggctcccg
     4741 ccatccggcg gcccgtcgtg gtgacggcgc ttttgagtgt gtgtttcatc tttccgtttt
     4801 cgtttcagtc tcctgccggg tccggtcctg taacaaaaaa acctttcccc ggtgggagaa
     4861 aggctttatt ttcaatcaac tatgcacgcc acctttctcc cgttatctcc gaaggacgac
     4921 gagcagcagg gtaatgacgt gaatattcga atgattcagg gcgttcatag ccggttttcc
     4981 gtgtttgttc gttttctgtg acagtgcatc cgcgtgcagg ccgggtctcc ctgttatgcc
     5041 ggatgctttc tgtc
//
