LOCUS       c00103_gnlPro..        13214 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDOHGMOA_103.
ACCESSION   c00103_gnlPro..
VERSION     c00103_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:13:48
            Original ID  :: gnl|Prokka|MDOHGMOA_103
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13214
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13214
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3407](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3407
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13214
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13214
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             3..3407
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_1"
                     /sec_met_domain="PFOR_II (E-value: 3.8e-19, bitscore: 58.3,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.8e-70, bitscore: 226.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 6e-32, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-05, bitscore: 14.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9.3e-26, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMI
                     PNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLA
                     GVAHLATIKSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMK
                     PVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAER
                     VIIAMGSVTEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRT
                     KEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNH
                     FTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHC
                     QAYFSYDSKKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNG
                     SFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFF
                     RITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDD
                     AKAENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWN
                     AENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCL
                     GCGNCADICPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQ
                     FATPLFEFSGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKG
                     HGPAWANSLFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNM
                     LDAEKTKELAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGL
                     DHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYG
                     YVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVK
                     CGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFK
                     AAEENAKWRYNSYKRLARENWGADTAE"
     CDS             3532..3720
                     /locus_tag="ctg103_2"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(3731..4591)
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(4619..5449)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg103_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.3e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(5446..6672)
                     /locus_tag="ctg103_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7145..8431
                     /locus_tag="ctg103_6"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(8394..8726)
                     /locus_tag="ctg103_7"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(8754..11507)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_8"
                     /sec_met_domain="Peripla_BP_1 (E-value: 6.1e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(11840..13066)
                     /locus_tag="ctg103_9"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGPHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 agaacatctt cggcgaaaca gtattggtac aggaaatgca atctgaaggt ggtgctgccg
       61 gtgcagttca cggttctctt caggctggtg cattgactac tacttacact gcttctcagg
      121 gtcttctttt gatgatccct aacatgtaca agattgccgg tgaattcttg ccttgtgtat
      181 tccacgtttc tgctcgtaca ctggcttctc acgcattgtg tatcttcggt gaccatcagg
      241 acgtaatgtc agctcgtcaa accggcttcg ctatgttggc agaaggttct gtacaggaag
      301 ttatggattt ggcaggtgtt gctcatctgg ctactatcaa atcacgcgtt ccgttcatga
      361 acttcttcga tggtttccgt acttctcacg aaatccagaa gatcgaaatg ttggaaaacg
      421 acgacctcgc tccgctgatc gaccaggaag ctttggctga attccgtgcc cgtgcactga
      481 atccgatgaa gccggttgcc cgtggtatgg ctgaaaaccc cgaccacttc ttccaacatc
      541 gtgaatcatg caataactac tatgaagcag ttcctgctat cgtagaagaa tacatgaacg
      601 aaatttccaa gatcacaggc cgcaaatacg gtttgttcga ttactacggt gcagaagatg
      661 cagaacgcgt aattatcgca atgggttctg taactgaagc tgcccgcgaa gctatcgacc
      721 acttggtagc aaacggcgaa aaagtaggta tggttgccgt acacttgtat cgtccgttct
      781 ctgctaaaca cttcctggct gctgtaccca agactgcaaa gagcatcgca gtgcttgacc
      841 gtacaaaaga accgggtgct aacggcgaac ctctttacct tgacgttaaa gactgcttct
      901 atggcgcaga aaatgctcct gttatcgttg gcggtcgcta cggtctgggt tctaaagata
      961 caactccggc acagatcatc tctgtattcg agaacttggc tatgccaatg ccgaagaacc
     1021 acttcactat cggtatcgta gacgacgtta cgttcacttc tcttcctcag aaagaagaaa
     1081 tcgctctggg cggtgaaggt atgttcgaag ctaaattcta cggtctgggt gctgacggta
     1141 ctgtaggtgc caacaagaac tctgttaaga ttatcggtga caacaccgac aaacactgtc
     1201 aggcttactt ctcttacgac tccaagaagt cgggtggttt cacttgttct cacttgcgtt
     1261 tcggtgatac tccgatccgt tctacttact tggtaaatac tccgaacttc gttgcttgtc
     1321 acgttcaggc ttacctgcac atgtacgacg taacacgtgg tttgcgtaag aacggttctt
     1381 tcttgctgaa taccatctgg gaaggcgaag aactggctaa gaacctgcct aacaaggtga
     1441 agaaatactt tgcacagaac aacatctctg tatactatat caacgcaact cagattgcaa
     1501 tggaaattgg tttgggcaac cgtaccaata caatccttca gtctgcattc ttccgtatca
     1561 caggcgtaat ccctgtagat caagctgttg aacagatgaa gaaattcatc gttaagtctt
     1621 acggcaagaa gggtgaagac gttgttaaca agaactacgc tgctgtagac cgcggtggtg
     1681 aatacaagac tctgactgtc gatcctgctt gggctaacct gccggatgat gcaaaagcag
     1741 aaaacaatga tcctgctttc atcaacgaag tagttcgtcc gatcaatgca caggacggtg
     1801 acttgctgcc ggtatctgca ttcaagggta tcgaagacgg tacttggtat caaggtactt
     1861 ccaaatacga aaaacgtggt gtagctgcat tcgttcccga atggaatgct gaaaactgta
     1921 ttcagtgtaa caagtgtgct tacgtttgtc ctcacgcttc tatccgtccg ttcgtactcg
     1981 atgctgaaga gcagaagggt gctaagttcg agcaactgaa agctgtaggt aaagcattcg
     2041 atggtatgac attccgtatt caggtagacg ttctcgattg tctgggttgc ggtaactgtg
     2101 ccgacatctg tccgggtaat ccgaagaagg gtggcaaggc attgaccatg aaacaccttg
     2161 aaagccagtt ggccgaagct gataactgga cttactgcgc tgaaaacgtg aagagcaaac
     2221 aacacctggt agacatcaag gctaacgtga agaactctca gttcgcaact ccgttgtttg
     2281 agttctcagg cgcttgctcc ggttgtggtg aaactccgta cgtgaaactg atttctcagt
     2341 tgttcggtga ccgtgaaatg gttgctaacg ctacaggatg ttcttctatc tactccggtt
     2401 cagttccttc tactccgtac actatgaacg aaaagggtca cggtcctgca tgggctaact
     2461 ccttgttcga agacttctgt gaatttggtc tgggtatgga actggctaac gaaaagatgc
     2521 gtgcccgtct ggtgaaagta atgaacgaag ctatcgcttc tgattgctgc ccggctgaat
     2581 acaaagaagt atttgctgaa tggatcaaca atatgctgga tgcagaaaag actaaggaac
     2641 tggccgaaaa gatcattccg atggtagaag ctgctaaaga taaatgcaac cactgcaagc
     2701 aaatcgctga tctgcaacaa tatcttgtta aacgcagcca atggatcatc ggtggtgacg
     2761 gtgcttctta tgatatcggt tacggtggtc ttgaccatgt aatcgcttcc ggtaaggacg
     2821 ttaacatcct tgtattggat actgaggttt actctaacac aggtggtcag tcttctaaag
     2881 ctactccggt aggcgctatc gctaagtttg ctgctgcagg taagcgtgta cgtaagaaag
     2941 acctcggtct gatggctact acttacggtt atgtatatgt tgctcagatt gctatgggtg
     3001 ctgaccaggc tcagactctg aaagctatcc gtgaagctga agcatatccg ggaccatcac
     3061 tgatcatcgc ttacgctcca tgtatcaacc acggtctgaa agccggtatg ggtaagagcc
     3121 aggaagaaga agaaaaggct gttaagtgcg gttactggca cttgtggcgt tacaaccctg
     3181 ctttggaaga agaaggcaag aatccgttcc aactggatag caaagaacct aactgggaag
     3241 acttccaagg tttcttgaag ggtgaagttc gttacgcttc tgtaatgaaa caatatcctg
     3301 ctgaagctga agaactgttt aaagctgctg aagaaaacgc taaatggcgt tacaacagct
     3361 acaaacgtct tgccagagaa aactggggag ctgatacagc tgaataataa gtagaaatac
     3421 tttgtacata ataaaaggca ggaatcctgg aaacagattc ctgccttttt tgtttatatc
     3481 ttagaagtaa cgattacttc tcacgaagat attcattaaa actctaaaga tatgatcgga
     3541 tttgttattt ggattatcgg tttgatactg actttcagag ctgccataga gatttggaat
     3601 ataaatgcgg ctgtagagaa aagacttata gcgattgtat taatcgttct taccagctgg
     3661 ctgggactac ttttctacta cttctatggt aaagaaagaa tggcgggatg gttgaagtag
     3721 tgtttgcata tcaatctttc tcaggaatcc aactgttcac cagttcctga tgttcttcca
     3781 tccattgacg ggcagcctgt ctttccgttg tctgcgcctc ttccagagca gtcattaagg
     3841 agctgatttc cgcatctgtc agacgaatgt tgcccaaaag ttcggcagca aaagggtctt
     3901 tctcgctaaa acctttccat gctatggtat gaatggattc cgtatttcca tatatcagct
     3961 tcgggtcctg aagaactttc agcttgaaac ggtcgaacat ccagtgaggc gtccatcccg
     4021 tcacgacaat ccagtctttc ttatcaatcg ctttctttag ggaagcagtc atggcaggtc
     4081 cgctcgaagt catcagttta taatccaatc catagtcttt gatggcctga tcggtagctt
     4141 tcataatacc ggctccggca tcaataccga caatctgacc ggagaaacgt tccttttccg
     4201 cgttcagttc ttcgattgag ttgatcgtaa cgtaatccgg aaccaccagc ccgatacggg
     4261 caccatcata aatatccccg ataacttcga gtttatcccc gtattgtttc atataatctt
     4321 ccatagtgac aggcatccag acatccataa atacgtctgc tttcttacgg gagatagagg
     4381 taaatatagg tgcaaggtcg gcattcagca actttacatc gtacccctga tcttcaaaaa
     4441 tcgctttggc aaggtttgtc attgcaatac cttccgacca gttggcataa gcgatactta
     4501 tcttcttact ctttccgttg tctccgcagg aaacgaaggt taagagtatg ccggcaataa
     4561 acattgccgc aatcattttt atcttattca ttgattattc ctttctttgg tgtgattctt
     4621 atttcttttt actttttctg ttatctgcca taccctgagt gatgcggtcc agcacgatcg
     4681 ccaatatcac gactgcgata ccgccttcaa atccgagtcc gattttcatt tgggtgatac
     4741 ctttcagcac gatttctccc aatcctccgg cagaaatcat ggcagcaatc actaccatcg
     4801 aaagtgacat catgatcgtc tggttgattc ccgtcagaat agtaggcaac gccaaaggca
     4861 attgcacctt ataaagaagc tgccagggag tagctccaaa agagcgggag gcttctacta
     4921 cgtttttagg aacctgacga atgcccagac cggtcagacg aaccacagga ggcattgcaa
     4981 agatgatggt ggcaaaagct cccggcacag ttcccaatcc gaagaataga acggcaggaa
     5041 tcagatagac aaaggcaggc attgtctgca taaagtcgag gacagggcgc attatcttgt
     5101 tacaacgatc actgttggca gtccagattc ccaacggaac gcctaaaagc aatgccagac
     5161 aagtggaaga aagtaccaat gccaatgtct gcatcgtttc ttcccaaaag cccatgccgt
     5221 aaataagcaa taaacccaag agggtaaata cggctgtccc cttacccgac ttaaaccagg
     5281 cgagcgcagc cagcactgca attgtgatat aaaaaggtat tccaaacagt acgtgctgaa
     5341 aaccgtctat gaatcctccg atccccatgc tgagagcatc aaaaaaggaa gcaaaatgtt
     5401 ctgtgagcca attaatggca gtctctatat attgtccgat atttatcata attctattgc
     5461 gttttgaatg atttcattaa tttcttcttt atcttttccc gttacttcga tgatcaatga
     5521 ggaaagtggc actacgcctt caaactcccg attctcattt acgacccaga ttggcgagtt
     5581 cgtttttgtc atcaacggaa gaatatcttc cagcaccgta tcacccagca ctgaatgaac
     5641 ttcatgcctt actacggact cgatggagcg gatttgctct tttcgtagtt tcagcaagtc
     5701 attcaaccgc acctctccta ctaacagatt attggaatcg actaccggaa gaacggtcag
     5761 attccgttcg cgcatcttac ggatcagcac ctccgggcct tctttcttca aacgtgccac
     5821 tatgggttta tctaccataa cagaggaagc tgttataatc ttgcttcgat ctacattctc
     5881 cacaaatcgt tctacataag cgttggcagg ttcggtcagg atttcttccg atgtaccgat
     5941 ttgtacaatt tctccatcct tcatgatagc aatccggtca cccaatttaa tcgcttcact
     6001 caggtcgtga gtaataaaga caatcgtttt tttcatcttc gactgcaaag tcagcagttc
     6061 atcctgcatc tgcacacgga tcaaaggatc gagtgccgag aaggcctcat ccatcaacag
     6121 gacttcggga ttattggcca aagcccgcgc cagcccgaca cgctgctgca tcccacccga
     6181 cagttcactt accatctgat tctcgtagcc tttcagcccc accagttgca tgctttccat
     6241 cgctttctgc tcccgttctc ccttttttac tccctgtagt tcgagcccga aagctatatt
     6301 atgcaagaca gaacggtgag gaagcagacc gaagttctga aagaccatag ccagttcttt
     6361 ccggcgaatc tgcaacagtt ccttatccga cactttggct atgtctgttc cattgataat
     6421 cacttctccg gaagtagggc gtatcaaacg gttgatgcag cggagtaaag tggactttcc
     6481 actaccggac agccccataa tgacgaatat ttcgccttca ttaatggaaa gattcgcatc
     6541 tttcaccgca actgtacatc cggtcgcttt caatatttca ctttttgttt taccttcttt
     6601 caacatcttc aaagccttct gcttctcatt gccaaaaacc agatagagat ctttaatttc
     6661 tattttactc atacaataaa atggtttagg ttattaaaat aatatacaca gcaagacaag
     6721 aacaaacgat aacaggaatc tttctttata tcgtataaag ttctgattta aatacgggac
     6781 aaataacaat gaatcccgaa ataattaata aaatgattat tgacagactg agtaattaaa
     6841 aaaggaatag aatttgataa gataatcctt tcaacgaata gcaaaaaata gcatttttat
     6901 gtataaaaac agcctgttcc agtatcttgc tggcacaaag atacaaaaaa cggattaaac
     6961 atacaaatta tattcaaaat ccggggcata cagagggctt tatttgtaat gatatggaaa
     7021 gtttccgggt aatattcccc tatcactcag caaaatagaa caaaccggca gataaatata
     7081 aaacaagttt gaatatttca cttaaacacc gtatatttgg cgtcaataac taaactagat
     7141 ttatatgttc aacagggcta ttacaatttt cctggggaag gataattgtc attacacaac
     7201 aaaagaaaaa caaacaggta ctgccacact agacgacaaa agccaagtac agttccttag
     7261 taaaaagaac cccaaaatgc cgtttttcta tagccggcgg aatctctaca tgataggttt
     7321 cctgctcgct tttatagtga ctctgctcga atttatacga ggacggcatc aaaactttat
     7381 ggtcttctcg gacgctactc aattcttctg gcaaggcatc agcccataca caactgaatt
     7441 tgtagaagct cacggacgct acttccttta ttctccagtt ttcacggtat tgttcgctcc
     7501 gtttgcgtat ctgcctgcat ggctgggacc tttcgcgtgg aatctattca attattcgct
     7561 gttctttatg gcgatcttca cgctgcccca acaattcacc cagcagcaga aatgccgtat
     7621 gttccttttt ctgttactga ttttaggaca aagtttactt tcatttcagt ataacataac
     7681 ggtagcctat ttattcttat tcgcctatac gttattggaa aaagaccgtg gatttctggc
     7741 tgttctgtta atcatgattt cgggatgtac caaagtatat ggaattttcg aactggcatt
     7801 gttgctgtgc tatcctcacg tatggcgtaa ctttggctat gccgttacaa tgggcattgt
     7861 attgcttgca ttaccgttaa taaaaatagc tcctgcagat ttgctcccct attatgaaga
     7921 atggtgccat agtcttgctg ttcatcagtc cgccggagct tatgattcat ttttctatgc
     7981 ccgccccatt gcagcatgga cattgccaca cttccgtgca cttcagatag gaatgctcgg
     8041 cttgctgact ctgctctttt tggggaattt ccgcaaatgg tcgtcttttg ccttccgtgc
     8101 ccaggctttg ggcattctca tgggctgggt agtattactg agtgactccg ccgagaagca
     8161 tacctatatt atcgcattgg caggtttcat gctctggtat tggagcagac caacacgtac
     8221 cgcaacagac aagattctat tttggtgctg ttttgtgctg ttatgtatcg ttcctatcga
     8281 catattcgtc cctgtaccca tcagagattt cattaccagg accttatggc ttcatgtatg
     8341 ggttttcttt attgtatgga tacggatgat atggcttacc ttccttgcat ccttcattca
     8401 tccacgtgcc acaaatgttc tttcagatta acgcatccgt tagctttgaa agaaacttct
     8461 tctgccagca agagttgttt ttgttccacc caaccgggca ccagccttcc ggtggaattt
     8521 acaactctat ggcagggaat ggataattca tccggcactt ctttcaatgc acgtcccacc
     8581 atccgcgagc attggggtgc ccccaacagc aaagcaatac ctccataagt agatactttt
     8641 cccacaggta tctgggatac gacttcgtac acttccttcc gaaaggattc ggaaaagctc
     8701 tctttatcta ctttataatc tttcatatat ccctctttac gatatcaatg aaatcatcct
     8761 ttccttttca ggaaatctgt cgggctctct ccaaactgct ctttatagca cttggcgaaa
     8821 taagaaggtg aactgaaacc gacttcataa ccaatctccg ctacggtcat gtccgaagaa
     8881 gcaagcaaag aagctgcctt cttcaaacgg gcgatacgga gcaattcatt cggagagtag
     8941 ttagtcaatg atttaatctt gcgataaagc tgcacacggc ttagtcccat gtctttgccc
     9001 aagtcctcca cattcaaacc ggagtctccc attttctctt caatcaatga cttgaatctt
     9061 tctacaaaat ccttgtccat atcgcagaca tcttcttttg ccaatgtctg cccgtcacca
     9121 aagaactgtt tcagacgacg gtgagaatcg atcagattgc ggacacgtgc cagcaacagc
     9181 tgtgaactga acggctttga aatataagaa tccgcaccac cgtcatatcc ctgaatacgc
     9241 tgttcgtcca gtgaacacgc tgtcagcaga ataaccggaa tatgacaggt ctgtaactca
     9301 cttttcagcc ggcggcaaca ttcaatgcca tcaatgcccg gcatcatcac atcagaaatg
     9361 atcaggtccg gaacatactt catagcctta cggattcctt cggagccgtc tgccgcttca
     9421 atcaccgtat agtctgtatg caacaacgta tggacatacg aacggatatc ctcattatca
     9481 tcaataatca gtacggacgg tttggaagag tcatatcctt tttccagttc ttcctcttcc
     9541 gccaatagaa catctgttgt acgggaatcc gcagaaacaa gggtggtatc cggttcggca
     9601 gcaacagcct cacaagactg tacaggcagt tcaacggtaa agaccgtgcc ctgtttctca
     9661 tcgctctcta cggagatcat accaccgtgc atttctacga aggcttttac caatgccagt
     9721 ccgattcccg aaccggtatg gtgcatatcg atcttataga aacggtcgaa tacattgcga
     9781 atatgttcgg cagaaatcat agaaccggta tttgccaccg tgaaacgtat ccatcgcttg
     9841 tcctctttac taagggaaga cagacggacg gctattttcc cgttttccgg tgtaaactta
     9901 aaggcattgg acagaagatt gaaataaata cgttccagct tctccatgtc tgccagtgta
     9961 tgataatccg tatccggcat actatcaaaa gaaaaatgga tatgcttctt acgggctgcc
    10021 gcctgaaaag actcattcca tccttcgaaa gaagaaagga catccaccgt aaccggagta
    10081 tattccatct tgccgttttc atatttacgg aaatccagaa tctgattgac cagacgcaga
    10141 aggatattca catttcgctg aatcagcatg agcatccggt gctgatctcc actcaatgtc
    10201 ttgtccgcca ataaatgttc taccgggtcg gcaaccaatg tcaacggagt acggaagtcg
    10261 tgagaaatat tggtgaaaaa gaccagcttg gcatgggtag cttcttccag ttgatgagag
    10321 agctgtatca attggtcacg ctgttcttcc agtttgtcac gctgctcttc caattgctgc
    10381 ttctgcttaa aaagctcttt attcaagcga ttcttagagc ggagtgattt ataaacgacc
    10441 aataataagc cggctaccaa taaaaggata atcagactgc cgtataaaac tacctgttgt
    10501 gtagctacct gagagaggta tccaccgata cgtccgttga gcgtttcaat ctttttatcg
    10561 agttcggaaa tgtgtgtggt ctgcaactgc atgacgtgtg cgttggtacg gtccacaaca
    10621 gcggtattca tcaccgtttc tttgggatag ggtttcttct ccagaatgtc catagccagt
    10681 tgcagtacct tatcgccatt ggtcggatag ataaaggtgg catccagcac actgtccagt
    10741 accagttcca gtccgtttcc cttacccggc aaggcatcta tgccgacaaa aatcatttcc
    10801 ttctcccgcc ctgccatctt tgctgcctga taggcacccg gagcgatacg gtcattatgg
    10861 gcatacacag catcaatctt aggatgcctc cgaagcatac tatccatttc tatctctgcc
    10921 ggaccacgtt cccacgcagc atccgcttta tcaatcagct ttatatccgg gaatttactg
    10981 atggcagcca taaatccctg atgccgttcc attgcaggag tcgaaccgct caatcctgtc
    11041 agttctacta tatttccctt cccttttaga ctggaggcaa tatagtttcc taccgaacga
    11101 ccgatttcat aattatcggc tccgatatag gcagtatatt tatccgaaag aatcttccgg
    11161 tctacaagaa taacggggat gcctttctga taagcttctt ctacaatcgg agtcatagga
    11221 gcagcttcgt tagcggaaat aatcagcaga tcgactcctt cgtccataaa ataatggaca
    11281 tcttccgcct gcttactgtt atcatcccct gccgaacgga tttccaccga aacaccatta
    11341 taaaacatcg cttcccgaag aatctcatca ttcatcttat gtcgccatga atcatcgctg
    11401 cattgagcca ccccaatacg aaaacggggt gtatcctgcc ggcaagccgt catcccgatt
    11461 aaaccaaaca gcaccagcat ccacttcaga tatctcatcg tcttcatcta tctcatcatt
    11521 tcatagttct ttctgtaatc caattaagaa caaaaataag aaataatact gtaaagttct
    11581 ctaacttcag ctatttatta ttctaaaaag aaggaaagca gtcctctttc agaccatcgg
    11641 aaagtattaa caaaagtata aagcgtaaaa caaacactta atcaatgtta taaaacatag
    11701 cgttttactt ggataatttg cagatttcac agaagtccgt atctttgcac tgtgtttttc
    11761 atagtattag atttaaggtt aacaaaggtt ggagcaaggc gttgctcctt tttttatgcc
    11821 ctgacctttc atctaccggt tagttttcat cccattcctt ttccagttta ccatcaatag
    11881 tgtagcgttt ccatcgtcct acacggcgac cattcttata ttccccacat tcacgaagct
    11941 ggtcattctt tacataacga gcttcgaacg gtccgttctg ccttccgttc acataggtag
    12001 aagtttccca ataatcaaag cggttgctca ctatcagccg tcgttccttg ccatgcaatc
    12061 tgccggcctg ataggtagct tcatatctca attcaccatt ttccagatta tattcacggt
    12121 ataaaccgtc tttacgatcg ttcttcatat aatattcttt ctgccttacc ccacttccgt
    12181 tggcaaatga gacatggggt ccatcttctt ttccatccag ataggtttca atcatcagcg
    12241 tatctccgct ttcagcaaaa gtagtccacc gaccattctt ctttccattc ttataactac
    12301 ccagtatacg tggcgagcca aacgtaaaca cggacgaata ttcaccgtcc tgcaaacctt
    12361 cttcattgaa ataaacggtc tcatacaaat catatgtacc tttcagaaaa gtatactgtt
    12421 tgcctacctg cttcccgtcc ttgtaattat gctctttccg caaagtaccg tcagattcgt
    12481 acgacagttg cttcccgtgc tctttcccca tccggaagtt tctttcactt tccacttttc
    12541 cggtagtaaa gtaacttttg ctcgtaccat ccagcttacc ttccttatag gacttttctt
    12601 ctttcagctt accgtcaaac ttggagttaa tcttgaagag gccatccttc cgcccttctt
    12661 tataacttcc ttccgttatt aatatattgt ccacatattc tttgtatccg ccatcataaa
    12721 aaccatcttt aaaagatgcc agcacatagg cggaatgata accatctatg atgcgatgtt
    12781 cgccattcaa tgctttttcc gttttcagtt cctgaaacaa cagtctgcca tcgcctacat
    12841 taacaacaga tacctgatcg atcttatatt ccttttgcgc aaacaaagga agagcaagat
    12901 ataaaaacaa aaatacgttc cagctttttg atctgaggaa gttcgaaatg tgtttcataa
    12961 agtagttttc tctttttgat ttattattta aaaacctgcc gcaaagatag gcaatcggct
    13021 tataaaacaa ggcaagaaag agggggacaa ttagaaaaaa gaacatctgt tattatcatt
    13081 ctaataatta acagattaag tagtaaatca aaacacaggg aagggggaca tttactgaaa
    13141 taagaaacag aaaagaagat gaattctaag tcctctccaa acaatatcta taaaatctta
    13201 cccaagttta cgaa
//
